The Additional Ring Shares The 5,10- Or 5,19-positions Of The Cyclopentanohydrophenanthrene Ring System Patents (Class 552/512)
  • Sulphur analogues of 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) for treating excess of glucocorticoids
    Patent number: 7479486
    Abstract: The present invention is related to novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues, their use as antiglucocorticoids for the treatment and/or prophylaxis of disease associated to an excess of glucocorticoids. In particular, the invention relates to the use of novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues for treating Cushing's syndrome, iatrogenic hypercortisolism or depression. Also the present invention is related to methods of preparing the novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: January 20, 2009
    Assignee: Laboratoires Serono SA
    Inventors: Gerardo Burton, Carlos P. Lantos, Adriana Silvia Veleiro
  • Sulfur analogues of 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) for treating excess of glucocorticoids
    Patent number: 7053228
    Abstract: The present invention is related to novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues, their use as antiglucocorticoids for the treatment and/or prophylaxis of disease associated to an excess of glucocorticoids. In particular, the invention relates to the use of novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues for treating Cushing's syndrome, iatrogenic hypercortisolism or depression. Also the present invention is related to methods of preparing the novel 21-hydroxy-6,19-oxidoprogesterone (21OH-6OP) analogues.
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: May 30, 2006
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Gerardo Burton, Carlos P. Lantos, Adriana Silvia Veleiro