The Additional Oxygen Is In A -c(=o)o- Group Patents (Class 554/107)
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Patent number: 11845892Abstract: Use of complex polyester amines and polyester quaternary ammonium compounds as corrosion inhibitors for metal surfaces, and a method for protecting a metal surface from corrosion by contacting the metal surface with said corrosion inhibitor.Type: GrantFiled: August 5, 2021Date of Patent: December 19, 2023Assignee: CLARIANT INTERNATIONAL LTDInventors: Dirk Leinweber, Tobias Platen, Nihal N. Obeyesekere, Matthias Krull
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Patent number: 10894900Abstract: A polyamide composition for use in sealants, adhesives and high solids coatings.Type: GrantFiled: May 19, 2020Date of Patent: January 19, 2021Assignee: Elementis Specialties, Inc.Inventors: Wouter Ijdo, Yanhui Chen, James Heck, Carlos Feito, Elke Piron
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Patent number: 10696862Abstract: A polyamide composition for use in sealants, adhesives and high solids coatings.Type: GrantFiled: August 21, 2019Date of Patent: June 30, 2020Assignee: Elementis Specialties, Inc.Inventors: Wouter Ijdo, Yanhui Chen, James Heck, Carlos Feito, Elke Piron
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Patent number: 9027757Abstract: The invention relates to the use of a composition of A) at least one quaternary ammonia compound comprising at least one organic radical bonded to the ammonia nitrogen atom and optionally comprising heteroatoms and having 1 to 36 carbon atoms, and B) at least one amine alkoxylate ester of formula (1) or a salt thereof, where A, B are, independently of each other, a C2- through C5-alkylene radical R1, a C8- through C24-alkyl radical or alkenyl radical R2, R3, R4 independent of each other, H, or a C8- through C24-acyl radical, with the stipulation that at least one of the radicals R2, R3 or R4 stands for a C8- through C24-acyl radical, and x, y, z, independently of each other, stand for a whole number from 0 through 50, with the stipulation that x+y+z is a whole number from 1 through 100, in quantities of 10 through 5000 g/tonne of ore as a collector in silicate floation.Type: GrantFiled: October 6, 2009Date of Patent: May 12, 2015Assignee: Clariant Finance (BVI) LimitedInventors: Klaus-Ulrich Pedain, Uwe Dahlmann
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Patent number: 8956646Abstract: In various embodiments, the present invention provides zwitterionic lipids, encapsulants incorporating these zwitterionic lipids and such encapsulants encapsulating one or more bioactive agent. An exemplary bioactive agent is a nucleic acid. Also provided are pharmaceutical formulations of the encapsulants and methods of using such formulations to deliver a bioactive agent to a subject in treating or diagnosing disease in that subject.Type: GrantFiled: August 15, 2011Date of Patent: February 17, 2015Assignee: The Regents of the University of CaliforniaInventors: Francis C. Szoka, Jr., Colin Walsh, Vincent Venditto, Juliane Nguyen, Emily Perttu
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Publication number: 20140308304Abstract: The present invention relates to novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides, to facilitate the cellular uptake and endosomal escape, and to knockdown target mRNA both in vitro and in vivo. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.Type: ApplicationFiled: December 7, 2012Publication date: October 16, 2014Inventors: Muthiah Manoharan, Kallanthottathil G. Rajeev, Muthusamy Jayaraman, Akin Akinc, Shigeo Matsuda, Martin Maier
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Publication number: 20140154940Abstract: A controlled release biocidal salt of a first component comprises a cation of a N?—(C1-C22) alkanoyl di-basic amino acid alkyl (C1-C22) ester cationic biocidal molecule and a second component comprising an anion of a monomeric anionic molecule having insignificant biocidal activity. The salt is characterized such that when the salt is exposed to an aqueous medium, the salt partially dissolves thereby releasing biocidal ions in an amount sufficient to exceed the MIC or MBC of a target bacteria being controlled, and further characterized as leaving a residual reservoir of undissolved salt capable of releasing more biocidal ions as the salt is consumed or otherwise removed from the environment encompassing the target bacteria. The preferred cationic biocidal molecule comprises N?-lauroyl-L-arginine ethyl ester (“LAE”).Type: ApplicationFiled: February 10, 2014Publication date: June 5, 2014Applicant: Nevada Naturals Inc.Inventors: Anthony J. Sawyer, Richard F. Stockel
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Publication number: 20130274492Abstract: The present invention relates to the use of a product obtainable by the reaction of a fatty acid, or mixture of acids, having the formula R1COOH (I); and a dicarboxylic acid or a derivative thereof having the formula (IIa) or (IIb) with an alkoxylated fatty amine having the formula (III) or a partial or wholly quaternised derivative thereof; optionally said reaction between the fatty acid, the dicarboxylic acid and the alkoxylated fatty amine is being followed by a further reaction step wherein part or all of the nitrogen atoms are quaternised by reaction with an alkylating agent R5X; as a corrosion inhibitor for metal surfaces. The present invention also relates to such products and to methods for their production.Type: ApplicationFiled: December 23, 2011Publication date: October 17, 2013Applicant: AKZO NOBEL CHEMICALS INTERNATIONAL B.V.Inventors: Per-Erik Hellberg, Natalija Gorochovceva
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Publication number: 20130237681Abstract: The present invention relates to novel amides having secondary amino groups, a process for preparing them, adducts of these amines and their uses. The amides can be prepared in a simple way from readily available starting materials. They and their adducts have, in particular, a low viscosity and are suitable as constituent of polyurethane and polyurea compositions having excellent processability and high flexibility, and also as constituent of epoxy resin compositions, in particular coatings.Type: ApplicationFiled: December 13, 2011Publication date: September 12, 2013Applicant: SIKA TECHNOLOGY AGInventor: Urs Burckhardt
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Publication number: 20130216607Abstract: In various embodiments, the present invention provides zwitterionic lipids, encapsulants incorporating these zwitterionic lipids and such encapsulants encapsulating one or more bioactive agent. An exemplary bioactive agent is a nucleic acid. Also provided are pharmaceutical formulations of the encapsulants and methods of using such formulations to deliver a bioactive agent to a subject in treating or diagnosing disease in that subject.Type: ApplicationFiled: August 15, 2011Publication date: August 22, 2013Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Francis C. Szoka, JR., Colin Walsh, Vincent Venditto, Juliane Nguyen, Emily Perttu
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Publication number: 20130072704Abstract: The present invention relates to a composition containing a particulate solid, a non-polar organic medium, and a compound obtained/obtainable by reacting an aromatic amine with hydrocarbyl-substituted acylating agent, wherein the hydrocarbyl-substituted acylating agent is selected from the group consisting of an oligomer or polymer from condensation polymerisation of a hydroxy-substituted C10-30 carboxylic acid into a polyester, an optionally hydroxy-substituted C10-30 carboxylic acid, a C10-30-hydrocarbyl substituted acylating agent, and a polyolefin-substituted maleic anhydride. The invention further provides compositions for inks, thermoplastics, plasticisers, plastisols, crude grinding and flush.Type: ApplicationFiled: November 16, 2012Publication date: March 21, 2013Applicant: LUBRIZOL ADVANCED MATERIALS, INC.Inventor: Lubrizol Advanced Materials, Inc.
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Publication number: 20130072703Abstract: The present invention relates to a composition containing a particulate solid, a non-polar organic medium, and a compound obtained/obtainable by reacting an aromatic amine with hydrocarbyl-substituted acylating agent, wherein the hydrocarbyl-substituted acylating agent is selected from the group consisting of an oligomer or polymer from condensation polymerisation of a hydroxy-substituted C10-30 carboxylic acid into a polyester, an optionally hydroxy-substituted C10-30 carboxylic acid, a C10-30-hydrocarbyl substituted acylating agent, and a polyolefin-substituted maleic anhydride. The invention further provides compositions for inks, thermoplastics, plasticisers, plastisols, crude grinding and flush.Type: ApplicationFiled: November 16, 2012Publication date: March 21, 2013Applicant: LUBRIZOL ADVANCED MATERIALS, INC.Inventor: Lubrizol Advanced Materials, Inc.
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Publication number: 20120318750Abstract: The present invention provides methods for decreasing amounts of metal ions in liquid materials and in porous solid materials surrounded by a liquid, by utilization of sequestering agents that form complexes with said metal ions as well as methods for removing and optionally recovering said metal ions from the complexes. Further, there are provided novel sequestering agents and compositions comprising sequestering agents of the present disclosure.Type: ApplicationFiled: December 10, 2010Publication date: December 20, 2012Applicant: ChemseQ International ABInventors: Ida Helena Högberg, Nils Frederik Andersson, Kjell Håkan Edlund, Sten Erik Hedenström, Hans Magnus Norgren
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Publication number: 20120164072Abstract: Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.Type: ApplicationFiled: May 4, 2010Publication date: June 28, 2012Inventors: Charles Linder, Sarina Grinberg, Eliahu Heldman
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Publication number: 20120129220Abstract: The present invention is aimed to provide a method for industrially producing a useful substance (protein etc.) utilizing a bacterium such as Escherichia coli in the presence of a surfactant and a surfactant to be used in this method for producing a useful substance. The present invention is a method for producing a useful substance into a culture solution by secretion by a bacterium in the culture solution, wherein the culture solution contains a surfactant (A), and a dried cell density based on the volume of the culture solution is 1.5 to 500 g/L. More preferably, the present invention is a method for producing a useful substance wherein the surfactant (A) is at least one agent selected from the group consisting of an amphoteric surfactant, an anionic surfactant, and a nonionic surfactant having an HLB value of 0 to 13.Type: ApplicationFiled: May 26, 2010Publication date: May 24, 2012Applicant: Sanyo Chemical Industries, Ltd.Inventors: Fusamitsu Yanagihara, Shunichiro Yamaguchi
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Publication number: 20110286958Abstract: Polymeric platinum amidomalonate complexes, where the platinum is in +2 or +4 oxidation state, and where the complexes optionally contain tumor seeking groups, are useful in the treatment of cancer.Type: ApplicationFiled: May 16, 2011Publication date: November 24, 2011Inventors: Paul Sood, N. Rao Ummaneni, Bruce Thurmond, Ryszard Zarzycki
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Publication number: 20110223257Abstract: The present invention relates to releasable fusogenic lipids and nanoparticle compositions containing the same for the delivery of oligonucleotides and methods of modulating gene expression using the same. In particular, this invention relates to releasable fusogenic lipids containing an imine linker and a zwitterionic moiety.Type: ApplicationFiled: November 17, 2009Publication date: September 15, 2011Applicant: ENZON PHARMACEUTICALS, INC.Inventors: Hong Zhao, Weili Yan, Lianjun Shi, Dechun Wu, Maksim Royzen
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Publication number: 20110136726Abstract: A novel class of antimicrobial polymeric agents which are designed to exert antimicrobial activity while being stable, non-toxic and avoiding development of resistance thereto and a process of preparing same are disclosed. Further disclosed are pharmaceutical compositions containing same and a method of treating medical conditions associated with pathological microorganisms, a medical device, an imaging probe and a food preservative utilizing same. Further disclosed are conjugates of an amino acid residue and a hydrophobic moiety residue and a process of preparing same.Type: ApplicationFiled: February 21, 2011Publication date: June 9, 2011Applicant: Technion Research & Development Foundation Ltd.Inventors: Amram MOR, Inna Radzishevsky
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Patent number: 7951842Abstract: This invention relates to the use of compounds of the general formula (I): R?—CONH—X—NR2R3—R4—Y in which R1 represents an alkyl moiety containing 11 to 21 carbon atoms, X stands for a (CH2)n- group and n is an integer from 1 to 6, R2 and R3 independently represent an alkyl moiety with 1 to 4 carbon atoms or an hydrogen atom, Y stands for a COO— group, in cosmetic compositions, characterized in that the compound of formula (I): is prepared by reacting the oil from Theo-broma grandiflorum with an amine of the formula (II): H2N—X—NR2R3 and subsequently reaction with sodium monochloroacetic acid.Type: GrantFiled: September 9, 2005Date of Patent: May 31, 2011Assignees: Cognis Brasil Ltda., Natura Cosmeticos S.A.Inventors: Rosa Maria Teixeira Tagé Biaggio, Setsuo Sato, Juliana Bucchi Alencastre, Carlos Alberto Moura, Henrique Sales, Tiago Costa Beber, Rosa Maria da Cunha Canto Friedlander, Tereza Maria de Senne Peranovich Victorio, Edjane dos Santos Lima
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Publication number: 20100286419Abstract: An improved thickening composition for organic systems, including paints and coatings, is described. The additive provides paints and coatings more than adequate viscosity improvement without affecting intercoat adhesion characteristics.Type: ApplicationFiled: July 15, 2010Publication date: November 11, 2010Applicant: ELEMENTIS SPECIALTIES, INC.Inventors: Mahalingam SANTHANAM, Wilbur Mardis
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Patent number: 7799565Abstract: The present invention provides lipid-based formulations for delivering, e.g., introducing, nucleic acid-lipid particles comprising an interference RNA molecule to a cell, and assays for optimizing the delivery efficiency of such lipid-based formulations.Type: GrantFiled: June 7, 2005Date of Patent: September 21, 2010Assignee: Protiva Biotherapeutics, Inc.Inventors: Ian MacLachlan, Lorne R. Palmer, James Heyes
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Publication number: 20100160213Abstract: The invention provides lipophilic conjugates comprising a peptide coupled to a fatty acid, the peptide comprising at least two positively charged amino acid residues, said peptide after conjugation to the fatty acid possessing antibacterial, antifungal, and/or anticancer activity higher than prior to conjugation. The lipophilic conjugates are suitable for treatment of infections caused by pathogenic organisms such as bacteria and fungi. The lipophilic conjugates are also suitable for sanitation, as disinfectants, or for food preservation.Type: ApplicationFiled: January 11, 2010Publication date: June 24, 2010Inventors: Yechiel Shai, Dorit Avrahami
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Patent number: 7714154Abstract: The present invention describes compounds produced from an amino acid molecule and a fatty acid molecule. The compounds being in the form of amino-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting amino acids or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental amino acids with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.Type: GrantFiled: April 8, 2008Date of Patent: May 11, 2010Assignee: Northern Innovations and Formulations Corp.Inventor: Joseph MacDougall
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Patent number: 7476749Abstract: The present invention describes compounds produced from a Creatinol molecule and a fatty acid molecule. The compounds being in the form of Creatinol-fatty compounds bound by an ester linkage, or mixtures thereof produced by reacting Creatinol or derivatives of Creatinol with an appropriate fatty acid in the presence of dichloromethane and an acid catalyst. The administration of such molecules provides supplemental Creatinol with enhanced bioavailability and having additional benefits conferred by the specific fatty acid.Type: GrantFiled: December 18, 2007Date of Patent: January 13, 2009Inventors: Marvin A. Heuer, Ken Clement, Shan Chaudhuri
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Patent number: 7465820Abstract: The present invention relates to heparin-binding calixarene compounds of general Formula (I) in which R, R1, L and n have the meanings indicated in the description and their use in the biomedical field.Type: GrantFiled: September 16, 2004Date of Patent: December 16, 2008Assignee: Consiglio Nazionale Delle RicercheInventors: Francesca Cunsolo, Grazia Maria Letizia Consoli, Corrada Geraci, Tommaso Mecca
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Patent number: 7314945Abstract: The present invention describes compounds produced from a creatine molecule and a fatty acid molecule. The compounds being in the form of creatine-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting creatine or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental creatine with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.Type: GrantFiled: February 20, 2007Date of Patent: January 1, 2008Assignee: Multi Formulations Ltd.Inventors: Shan Chaudhuri, Joseph MacDougall, Jason Peters, James Ramsbottom
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Patent number: 6916777Abstract: Novel fatty acids and derivatives thereof such as salts, new surfactant systems comprising one or more of these compounds, consumer products such as laundry products, personal care products, pharmaceutical compositions, industrial cleaners, and the like comprising said compounds or surfactant systems.Type: GrantFiled: April 24, 2003Date of Patent: July 12, 2005Assignee: The Procter & Gamble CompanyInventors: Daniel Stedman Connor, Jeffrey John Scheibel, Deborah Jean Back, Toan Trinh, Phillip Kyle Vinson, Roland George Severson, Thomas Anthony Cripe, James Charles Theophile Roger Burckett-St. Laurent, Mark Robert Sivik, Errol Hoffman Wahl, Gayle Marie Frankenbach, Marc Johan Declercq, Hugo Jean Marie Demeyere
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Patent number: 6696606Abstract: A solid phase synthetic method for preparing arylretinamides is provided. The method comprises reacting hexachloroacetone with a solvent-suspended resin-bound triphenylphosphine to provide a suspension comprising an activated chlorinating reagent; reacting retinoic acid with the activated chlorinating reagent to provide retinoyl chloride; adding pyridine and a select arylamine to the resulting mixture; and stirring the resulting mixture for a time and at a temperature sufficient for the select arylamine to react with the retinoyl chloride and provide the arylretinamide. Also provided, are select arylretinamides that can be prepared by the present method, and methods of using such arylretinamides to induce apoptosis in cancer cells.Type: GrantFiled: July 8, 2002Date of Patent: February 24, 2004Assignee: The Ohio State University Research FoundationInventors: Robert W. Curley, Jr., Serena M. Mershon
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Patent number: 6569411Abstract: Serine carbonates of formula I are precursors for organoleptic compounds, masking agents and antimicrobial agents. Further they are alternative substrates for malodor producing enzymes. The symbols in formula I are defined in claim 1.Type: GrantFiled: August 15, 2002Date of Patent: May 27, 2003Assignee: The Gillette CompanyInventors: Georg Frater, Denise Anderson, Frank Kumli, Jens Wittenberg, Virginia Streusand Goldman
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Patent number: 6562780Abstract: Esters derived from alkanolamines, dicarboxylic acids and fatty alcohols and the cationic surfactants obtainable therefrom. Novel alkanolamine esters based on the esterification reaction of alkanolamines, optionally alkoxylated, dicarboxylic acids and fatty alcohols, optionally alkoxylated, as well as the cationic surfactants and esterquats obtainable therefrom, are described. The cationic surfactants and esterquats thus obtained exhibit a high degree of efficacy in softening and conditioning natural and synthetic fibers such as textiles, paper and hair, and are therefore usable in treatments for softening and conditioning the said fibers. Novel aqueous fabric-softening compositions which contain the cationic surfactants and esterquats mentioned, optionally in combination with other active softening substances, are also described.Type: GrantFiled: April 22, 2002Date of Patent: May 13, 2003Assignee: Kao CorporationInventors: María José Osés Bermejo, Josep Ferrer Vilaret, Marisa Tomás Mumbr{overscore (u)}
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Publication number: 20030078417Abstract: The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for treating or prophylactically inhibiting phospholipase mediated injury, injury due to oxidation, and inflammation. In a very specific sense, this invention provides compositions and methods of making these compositions that are inhibitors of phospholipase.Type: ApplicationFiled: January 10, 2002Publication date: April 24, 2003Inventors: Richard C. Franson, Raphael M. Ottenbrite
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Publication number: 20030049310Abstract: The present invention relates to synthetic cationic lipids, liposome formulations and the use of such compounds to introduce functional bioactive agents into cultured cells.Type: ApplicationFiled: August 20, 2002Publication date: March 13, 2003Applicant: Vanderbilt UniversityInventor: Xiang Gao
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Patent number: 6489495Abstract: This invention relates to the synthesis of novel cationic, amphiphilic lipids and their application as gene transfer vehicles in vitro and in vivo. For this a series of different lipids (diglycerides, steroids) were synthesized by modification with variable cationic molecules (amino acids, biogenic amines). Compounds of this kind are, due to their capability of producing complexes with polynucleotides (DNA, RNA, Antisense oligonucleotides, ribozymes etc) suitable as vectors for gene transfer (transfection).Type: GrantFiled: July 3, 2001Date of Patent: December 3, 2002Assignee: Max-Delbrück-Centrum für Molekulare MedizinInventors: Manfred Schneider, Oliver Keil, Regina Reszka, Detlef Groth
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Patent number: 6458837Abstract: The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to the present invention are stable lipophilic diesters comprising a covalent conjugate of a BAPTA and a pharmaceutically acceptable alcohol. The diesters are useful in a method for treating a condition or disease related to an excess of divalent metal ions, and in particular for the treatment of a condition or disease related to elevated levels of intracellular calcium ions, such as in brain or cardiac ischemia, stroke, epilepsy, Alzheimer's disease or cardiac arrhythmia and in open heart surgery.Type: GrantFiled: March 27, 2000Date of Patent: October 1, 2002Assignee: D-Pharm Ltd.Inventors: Alexander Kozak, Israel Shapiro
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Patent number: 6355629Abstract: The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to intracellular enzyme activity. The prodrug may be used in a technique for treating a condition or disease in a mammal related to supranormal intracellular enzyme activity, whereby on administering it to a human having such condition or disease, the bond is broken in response to such activity, and the pharmacologically active compound is activated selectively within cells having such supranormal intracellular enzyme activity.Type: GrantFiled: February 6, 2001Date of Patent: March 12, 2002Assignee: D-Pharm Ltd.Inventor: Alexander Kozak
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Publication number: 20020002296Abstract: The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for treating or prophylactically inhibiting phospholipase mediated injury, injury due to oxidation, and inflammation. In a very specific sense, this invention provides compositions and methods of making these compositions that are inhibitors of phospholipase.Type: ApplicationFiled: January 12, 2000Publication date: January 3, 2002Inventors: Richard C. Franson, Raphael M. Ottenbrite
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Publication number: 20020002297Abstract: Polyquaternaries which are obtained by reacting at least one alkyldialkanolamine with a mixture of acids comprising at least one fatty acid and at least one dicarboxylic acid are disclosed. The inventive quaternaries have improved properties, such as softness, dispersibility and high biodegradeability; therefore, the inventive esterquats are highly useful as a component in rinse cycle fabric softeners, dryer sheets, hair conditioners, paper debonders and other applications in which a high degree of softness is required.Type: ApplicationFiled: June 1, 2001Publication date: January 3, 2002Inventor: Robert O. Keys
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Patent number: 6268516Abstract: This invention relates to the synthesis of novel cationic, amphiphilic lipids and their application as gene transfer vehicles in vitro and in vivo. For this a series of different lipids (diglycerides, steroids) were synthesized by modification with variable cationic molecules (amino acids, biogenic amines). Compounds of this kind are, due to their capability of producing complexes with polynucleotides (DNA, RNA, Antisense oligonucleotides, ribozymes etc) suitable as vectors for gene transfer (transfection).Type: GrantFiled: March 30, 1999Date of Patent: July 31, 2001Assignee: Max-Delbruck-Centrum fur Molekulare MedizinInventors: Manfred Schneider, Oliver Keil, Regina Reszka, Detlef Groth
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Patent number: 6207173Abstract: Lysine derivatives, salts of the derivatives, their optical isomers of D or L configuration, or their mixtures, the derivatives containing an Ne-alkoxy or Ne-alkenoxycarbonyl group and having the formula: in which: R represents a linear or branched C13-C24 alkyl radical or alkenyl radicals, are used in cosmetic, pharmaceutical, hygiene or food compositions, particularly compact compositions.Type: GrantFiled: April 23, 1999Date of Patent: March 27, 2001Assignee: L'OrealInventors: Michel Philippe, Thierry Bordier
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Patent number: 6187938Abstract: The invention relates to amino acid derivatives of general formula (I), wherein R1 is H or CH3, X is H or NR2R3, wherein R2 is H, CH3, COH or COCH3 and R3 is H, CH3 or COO—Z wherein Z is R2R3 NH+CHR1(CH2)nCOO(CH2)mCH2Y; Y is H, CH3 or NHR4, wherein R4 a COO—NH3+CH2(CH2)mOOC(CH2)nCH3, the meaning of group (CH2)m being selected from alkyls, secondary alkyls, monocycloalkyls, bicycloalkyls and tricycloalkyls having from 4 to 15 carbon atoms and n having a value of from 3 to 14.Type: GrantFiled: December 21, 1999Date of Patent: February 13, 2001Assignee: Bochemie, s.r.o.Inventors: Alexandr Hrabálek, Pavel Dole{haeck over (z)}al, Old{haeck over (r)}ich Farsa, Ale{haeck over (s)} Krebs, Ale{haeck over (s)} Kroutil, Martin Roman, Zde{haeck over (n)}ka {haeck over (S)}klubalová
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Patent number: 6150542Abstract: The invention relates to agents preventing (the formation of) human malodor. In particular, the invention relates to the use of several classes of compounds which can act as such agents in cosmetic products, such as deodorants and antiperspirants. These compounds are normally odorless or nearly so, but upon contacting the skin as for example, in skin care compositions or in personal care compositions, they prevent malodor.The compounds under consideration are compounds of the formula:X--(Z).sub.n --CO--NH--CH--(COO--Y)--CH.sub.2 CH.sub.2 CONH.sub.2I.Type: GrantFiled: April 13, 1999Date of Patent: November 21, 2000Assignee: Givaudan Roure (International) SAInventors: Gonzalo Acuna, Georg Frater, Peter Gygax
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Patent number: 5925339Abstract: The invention relates to agents preventing (the formation of) human malodor. In particular, the invention relates to the use of several classes of compounds which can act as such agents in cosmetic products, such as deodorants and antiperspirants. These compounds are normally odorless or nearly so, but upon contacting the skin as for example, in skin care compositions or in personal care compositions, they prevent malodor. The compounds under consideration are compounds of the formulaX--(Z).sub.n --CO--NH--CH--(COO--Y)--CH.sub.2 CH.sub.2 CONH.sub.2IThe definition of the substituents is given in the specification.Type: GrantFiled: June 19, 1997Date of Patent: July 20, 1999Assignee: Givaudan Roure SAInventors: Gonzalo Acuna, Georg Frater, Peter Gygax
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Patent number: 5869716Abstract: Esterquats based on natural fats and oils can be directly produced by subjecting fatty acid glyerine ester to ester interchange, in the presence of alkaline and/or alkaline earth boron hydrides and hypophosphoric acid or their alkaline and/or alkaline earth salts and possibly free fatty acid, with hydroxy-functionalised tertiary amines and quaternising the resultant products in the manner known per se.Type: GrantFiled: September 16, 1996Date of Patent: February 9, 1999Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Rafael Pi Subirana, Joaquim Bigorra Llosas, Antonio Trius Oliva
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Patent number: 5741816Abstract: Disclosed is a hair-growing (restoration) agent which comprises a carnitine compound represented by the formula (I): ##STR1## wherein R.sup.1 to R.sup.3 each represent an alkyl group having 1 to 6 carbon atoms; R.sup.4 represents an aliphatic acyl group having 3 to 31 carbon atoms which may be substituted; R.sup.5 represents an alkyl group having 3 to 31 carbon atoms which may be substituted, or an alkenyl group having 3 to 31 carbon atoms which may be substituted; and X.sup.- represents an anion of a pharmaceutically acceptable acid,as an active ingredient.Type: GrantFiled: June 6, 1995Date of Patent: April 21, 1998Assignee: Tanabe Seiyaku Co., Ltd.Inventors: Kenji Tsujihara, Kunio Saito, Satoshi Furuuchi
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Patent number: 5670472Abstract: Disclosed are compounds of the formula (I) ##STR1## useful as fabric softening compounds which exhibit enhanced biodegradability.Type: GrantFiled: May 26, 1995Date of Patent: September 23, 1997Assignee: Witco CorporationInventor: Robert O. Keys
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Patent number: 5654452Abstract: Aromatic acid-derived lipophilic polyhalogenated compounds are provided for use as contrast agents in diagnostic imaging or as therapeutic agents. These compounds are particularly useful when incorporated into an oil-in-water emulsion for tissue-specific delivery to the liver. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm and having a composition simulating naturally-occuring chylomicron remnants.Type: GrantFiled: June 7, 1995Date of Patent: August 5, 1997Assignee: Molecular Biosystems, Inc.Inventors: Rolf Lohrmann, Dung K. Hong
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Patent number: 5625085Abstract: Esters of alkanoyl L-carnitines wherein the alkanoyl is a saturated or unsaturated, straight or branched alkanoyl having 2-26 carbon atoms, optionally .omega.-substituted with trialkylammonium, dialkylsulfonium, hydroxyl, carboxyl, halogen, methanesulfonyl and hydroxysulfonyl, are useful for preparing pharmaceutical compositions for the treatment of endotoxic shock.Type: GrantFiled: July 14, 1994Date of Patent: April 29, 1997Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.Inventors: Piero Foresta, Vito Ruggiero, Maria O. Tinti, Nazareno Scafetta
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Patent number: 5578234Abstract: The present invention relates to dryer-activated fabric softening compositions and articles, having improved antistatic and/or softening effects, for use in an automatic clothes dryer, especially those comprising, as essential ingredients: (A) fabric softener consisting essentially of: (1) from about 5% to about 95% of preferably biodegradable quaternary ammonium compound selected from the group consisting of the compounds of Formulas I, II, III, and mixtures thereof; (2) from 0% to about 95% highly ethoxylated and/or propoxylated, preferably at least 5 ethylene oxide (EO) and/or propylene oxide (PO) groups per molecule, sugar derivative containing at least one long hydrophobic moiety per molecule; and (3) from 0% to about 95% of carboxylic acid salt of tertiary amine; and (B) from about 1% to about 15%, unsaturated fatty acid having an IV of from about 3 to about 60. The amount of (A) present is at least sufficient to provide softening and/or antistatic effects.Type: GrantFiled: October 10, 1995Date of Patent: November 26, 1996Assignee: The Procter & Gamble CompanyInventors: Alessandro Corona, III, Clyde D. Palmer, John R. Rusche, Stephanie Lin-Lin Sung
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Patent number: 5391812Abstract: Polyglycolate compounds are provided having the general structure: ##STR1## wherein n is an integer from 2 to about 10; R is C.sub.1-20 linear or branched alkyl, alkoxylated alkyl, cycloalkyl, aryl, alkylaryl, substituted aryl; R' and R" are independently H, C.sub.1-20 alkyl, aryl, C.sub.1-20 alkylaryl, substituted aryl, and NR.sub.3.sup..alpha.+, wherein R.sup..alpha. is C.sub.1-30 alkyl; and L is a leaving group displaceable in a peroxygen bleaching solution by perhydroxide anion. When this compound is combined with a source of peroxygen in aqueous solution, then a plurality of stain removing peracids are formed. Such peracids are formed substantially sequentially beginning with the carbonyl adjacent to the leaving group L. Thus, a first stain removing peracid having the structure ##STR2## will be formed in amounts approaching quantitative yield.Type: GrantFiled: September 25, 1992Date of Patent: February 21, 1995Assignee: The Clorox CompanyInventors: Richard R. Rowland, Ronald A. Fong, Richard J. Wiersema, Alfred G. Zielske
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Patent number: 5334761Abstract: The present invention discloses cationic lipids useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Also disclosed are lipids useful both for the delivery of macromolecules and also useful as intermediates for making other such lipids.Type: GrantFiled: August 28, 1992Date of Patent: August 2, 1994Assignee: Life Technologies, Inc.Inventors: Gulilat Gebeyehu, Joel A. Jessee, Valentina C. Ciccarone, Pamela Hawley-Nelson, Anna Chytil