Another Reactant Is A Carboxylic Acid Salt Patents (Class 554/152)
  • Patent number: 9150504
    Abstract: The invention relates to fatty acid guanidine or salicylate guanidine derivatives; compositions comprising an effective amount of a fatty acid guanidine or salicylate guanidine derivative; and methods for treating or preventing a metabolic disease comprising the administration of an effective amount of a fatty acid guanidine or salicylate guanidine derivative.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: October 6, 2015
    Assignee: Catabasis Pharmaceuticals, Inc.
    Inventors: Jill C. Milne, Michael R. Jirousek, Jean E. Bemis, Chi B. Vu, Amal Ting
  • Patent number: 7511163
    Abstract: The present invention describes compounds produced from a creatine molecule and a fatty acid molecule. The compounds being in the form of creatine-fatty compounds bound by an amide linkage, or mixtures thereof produced by reacting creatine or derivatives thereof with an appropriate fatty acid in the presence of dichloromethane and a pyridine catalyst, previously reacted with a thionyl halide. The administration of such molecules provides supplemental creatine with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: March 31, 2009
    Assignee: Multi Formulations Ltd
    Inventors: Shan Chaudhuri, Joseph MacDougall, Jason Peters, James Ramsbottom
  • Patent number: 7511164
    Abstract: The present invention describes compounds produced from a creatine molecule and a fatty acid molecule. The compounds being in the form of creatine-fatty acid compounds being bound by an anhydride linkage, or mixtures thereof made by reacting creatine or derivatives thereof with an appropriate fatty acid previously reacted with a thionyl halide. The administration of such molecules provides supplemental creatine with enhanced bioavailability and the additional benefits conferred by the specific fatty acid.
    Type: Grant
    Filed: September 17, 2007
    Date of Patent: March 31, 2009
    Assignee: Multi Formulations Ltd
    Inventors: Shan Chaudhuri, Joseph MacDougall, Jason Peters, James Ramsbottom
  • Publication number: 20040024232
    Abstract: The present invention relates to a process for the preparation of trans-alkenoic acids of general formula CH3—(CH2)n—CH—(CH2)m CO2H where n=4 to 9 m−8 to 16. More particularly, the present invention relates to a process for he preparation of trans-tetracos-15-enoic acid, which is a bioactive constituent possessing dose-related hepatoprotective activity. The present invention also relates to the use thereof for hepatoprotection.
    Type: Application
    Filed: March 28, 2002
    Publication date: February 5, 2004
    Inventors: Vishwa Nath Gupta, Vikram Bhardwaj, Bhupinder Singh, Bal Krishan Chandan, Krishan Avtar Suri, Naresh Kumar Satti, Om Parkash Suri, Sukhdev Swami Handa
  • Patent number: 5235077
    Abstract: An improved process for preparing phenyl esters of alkanoyloxyacetic acids in which phenyl chloroacetate is reacted with the salt of a carboxylic acid.
    Type: Grant
    Filed: March 25, 1991
    Date of Patent: August 10, 1993
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Bijan Amini, Donald J. Dumas, Ronald A. Fong, George C. Sonnichsen