Abstract: Compositions that include cationic surfactants and methods of synthesizing compositions that include cationic surfactants. The surfactants include a quaternary amine and a saturated or unsaturated alkyl chain with 4 to 28 carbons. The surfactants can be generated by reacting a fatty acid modified with an amino alkyl group and an epihalohydrin in the presence of a base. The cationic surfactants can be generated by reacting a fatty acid modified with an amino alkyl group, an epihalohydrin, and a carboxylic acid. The cationic surfactants can be generated by reacting a carboxylic acid, an epihalohydrin, and a catalyst to afford a halo-substituted alkyl ester, followed by reacting the halo-substituted alky ester with a fatty acid modified with an amino alkyl group.

Abstract: A dishwashing composition which is a mixture of vinegar powder and lemon powder, or a mixture of vinegar powder, lemon powder and salt, for use in a dishwashing machine or for other cleaning purposes. The vinegar powder, lemon powder and, when present, salt can be mixed in any of a variety of proportions. The lemon powder, vinegar powder, and optional salt are non-toxic to humans and pets.

Abstract: A dishwashing composition made by mixing vinegar powder and lemon powder for use in a dishwashing machine or for other cleaning purposes. The vinegar powder is mixed with the lemon powder in any of a variety of proportions. Both the lemon powder and the vinegar powder are non-toxic to humans and pets.

Abstract: A fuel soluble additive for a diesel engine, a method for improving performance of fuel injectors and a method for cleaning fuel injectors for a diesel engine. The fuel soluble additive includes a quaternary ammonium salt derived from an amido amine containing at least one tertiary amino group and an epoxide, in the presence of a proton donor selected from a carboxylic acid and an alkyl phenol. The amido amine is made in a reaction medium that is substantially devoid of an acylating agent.

Abstract: A fuel additive and its preparation for a engine, a fuel containing the additive, a fuel additive concentrate, a method for improving performance of fuel injectors and a method for cleaning fuel injectors for an engine. The fuel additive includes a quaternary ammonium salt derived from a reaction of a hydrocarbyl substituted anhydride, a tertiary amine and a hydroxyl-containing epoxide, wherein the tertiary amine is devoid of primary and secondary amino groups.

Abstract: Acidic viscoelastic cleaning compositions are disclosed which use non polymer thickening agents. According to the invention, cleaning compositions have been developed using viscoelastic surfactants in acidic cleaning formulations. These provide the dual benefit of thickening as well as an additional cleaning, thereby improving performance. Applicants have also identified several pseudo linking agents which when, used with viscoelastic surfactants provide enhanced viscoelasticity and cleaning.

Abstract: Alkaline or neutral viscoelastic cleaning compositions are disclosed which use non polymer thickening agents. According to the invention, cleaning compositions have been developed using viscoelastic surfactants in a neutral, acidic or alkaline cleaning formulations. These provide the dual benefit of thickening as well as an additional cleaning, thereby improving performance. Applicants have also identified several pseudo linking agents which when, used with viscoelastic surfactants provide viscoelasticity in alkaline cleaning compositions.

Abstract: Esterquats (reaction products of a fatty acid source and a trialkanolamine) having a desirable distribution of mono-, di-, and tri-quat esters, such as at least 55 wt. % of the diester and at most 25% of the triester, can be produced by heating a trialkanolamine and a fatty acid source at a temperature ramp rate of 0.4° C. per minute or less. This result can be achieved, for example, by reducing the amount of catalyst to a suboptimal amount for rapid formation of the quat diester.

Abstract: The present invention discloses a process for the production of a fatty acid/L-carnitine derivative, whereby the educts are reacted in the presence of monochloroacetic acid.

Abstract: An ophthalmic oil-in-water type emulsion, which includes colloid particles having an oily core surrounded by an interfacial film, the emulsion including at least one cationic agent, at least one no ionic surfactant, the emulsion having a positive zeta potential and meeting zeta potential stability Test A requirements. Process for making the emulsions. Delivery device selected from the group including lenses, ocular patch, implant, insert, the device containing an emulsion according to the invention.

Abstract: A well tolerated oil-in-water emulsion useful as a delivery vehicle of hydrophobic ingredients such as pharmaceutical drugs, wherein the emulsion particles have a net positive charge and comprises 0.001 to 0.1% of a cationic agent, 0 to 1% of a non ionic surfactant and 0 to 0.5% of an anionic surfactant.

Abstract: Ophthalmic oil-in-water emulsions, which comprises colloid particles having an oily core surrounded by an interfacial film, the emulsion comprising an 10 immunosuppressive agent, an oil, preferably at least 50% of which being MCT, and tyloxapol. Use of such an emulsion for the manufacture of medicament for treatment of eye conditions, particularly of dry eye diseases.

Abstract: The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid reacted with a combination of a monohydroxy functional amine and a specific di-hydroxy functional tertiary alkanolamine, to make an ester tertiary amine, which is a subsequent step is converted to a quaternary compound. Dimer acid is a C-36 diacid having a cyclic structure and reacting it with the two type of amine groups allow for the synthesis of a high molecular weight cationic compound which is extremely substantitive to human skin and are well tolerated by human tissue making them suitable for use preparation of barrier products for personal care applications. These materials are dimethylaminopropyl amine free, which is highly desirable in personal care applications.

Abstract: To provide novel carnitine derivatives and salts thereof that are resistant to hydrolysis in the presence of aqueous media, and also provide external skin preparations and cosmetics that are excellent in storage stability, product life, skin affinity and percutaneous absorption properties. In particular, to provide novel ?-branched acyl carnitine derivatives and salts thereof, external skin preparations and cosmetics comprising specific ?-branched acyl carnitine derivatives and/or salts thereof.

Abstract: The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid reacted with an alkanolamine to make an ester quaternary compound. Dimer acid is a C-36 diacid having a cyclic structure and two amine groups that allow for the synthesis of a high molecular weight cationic compound which is extremely substantitive to human skin and are well tolerated by human tissue making them suitable for use preparation of barrier products for personal care applications. These materials are dimethylaminopropyl amine free, which is highly desirable in personal care applications.

Abstract: The present invention provides amphiphilic diacetylene compounds, and compositions and self-assembled nanotubes containing the same. Also provided are methods of producing the compounds, compositions, and nanotubes of the invention, and methods of destroying or inhibiting the growth or proliferation of microorganisms using the nanotubes of the present invention.

Abstract: Compounds and compositions the same. Method of making the compounds. The compounds and/or compositions used as an analgesic, anaesthetic, antifoulant, aversant, irritant, sternutator, neurodegenerator, counter irritant (delayed), rubifaciant, stomachic, fungicide, insecticide, preservative, circulatory stimulant, cardio-protective agent, immune booster, decongestant, anti-inflammatory agent, incapacitant, biocide, mildewcide, pharmaceutical, repellent, flavorant, carminative, antismoking agent, and/or antithrombotic agent. One of the compounds being lidocaine nonivamide. The compositions comprising one or more of: the compounds, one or more of an antioxidant, a UV absorber, and one or more biocides such as, for example, OBPA.

Abstract: An aqueous composition for oral care application comprising solution of an amidobetaine of the following general Formula I is disclosed; in which R is an alkyl of coconut fatty acids, preferably hydrogenated coconut fatty acids, or a fatty acid mixture group which, on the average, corresponds to coconut fatty acids, wherein the solution has a solids content of 36% by weight, a pH of 4.5 to 6, an alkylamidopropyldimethyl amine content of not more than 0.1% by weight, and a free fatty acid content less than 0.5% by weight, sodium chloride content of 6.0% max and dimethylaminopropylamino betaine (from N,N-dimethyl amino propyl 1,3-diamine (DMAPA) and monochloroacetic acid) content of 30 ppm max, free sodium monochloroacetic acid content of 5 ppm max and free N,N-dimethylamino propyl 1,3-diamine content of 5.0 ppm max.

Abstract: Water-soluble and water dispersible undecylenic amido propyl dimethyl hydroxyl ethoxy ethyl ammonium undecylenate compounds of formula I having anti-dandruff, preservative and sunscreen activity wherein R1, R2 are from C1-C6 carbon atoms, R3 is undecylenic acid, amino group is selected from dimethyl amino propyl amine.

Abstract: Quaternary surfactants of the formula (I), wherein R1CO is a linear or branched, saturated or unsaturated, optionally hydroxy-functionalized acyl radical having 6 to 22 carbon atoms and 0, 1, 2 or 3 double bonds, R2 is a CH2COOH radical, an alkyl radical having 1 to 4 carbon atoms, a CH2CH2OH or a CH2CH2OCH2CH2OH group, and X is halide, alkyl sulfate, alkyl carbonate or alkyl phosphate, are useful as surfactants in cosmetic and pharmaceutical preparations. Aqueous solutions above 50% by weight of the surfactants are flowable and pumpable.

Abstract: The present invention relates to raspberry seed oil derivatives derived by the reaction of dimethyl amino propyl amine and cold pressed raspberry seed oil. This intermediate is subsequently reacted with sodium monochloroacetic acid to make a raspberry betaine. The choice of cold pressed raspberry seed oil as a raw material in the preparation of the compounds of the present invention is critical, since it has been found that the cold pressed raspberry seed oil contains antioxidants, antimicrobial compounds and which when reacted with a DMAPA result in products that deliver said actives to the skin and hair, resulting in protection of the skin and hair from environmental factors such as acid rain, ozone attack and UV degradation.

Abstract: A quaternary surfactant comprising a cyclic diamine group, compositions comprising the quaternized amido cyclic amine surfactant, a gelled aqueous composition comprising the quaternized amido cyclic amine surfactant, use of the gelled aqueous well treatment applications and methods of preparation and intermediates used to prepare the quaternized amido cyclic amine surfactant.

Abstract: The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid amido amine quaternary compound. Dimer acid is a C-36 diacid having a cyclic structure and two amine groups that allow for the synthesis of a high molecular weight cationic compound which is extremely substantitive to human skin and are well tolerated by human tissue making them suitable for use preparation of barrier products for personal care applications.

Abstract: Novel fatty acids and derivatives thereof such as salts, new surfactant systems comprising one or more of these compounds, consumer products such as laundry products, personal care products, pharmaceutical compositions, industrial cleaners, and the like comprising said compounds or surfactant systems.

Abstract: The present invention relates to novel covalent derivatives of alkanolamides of monocarboxylic and dicarboxylic acids with aminoalcohols of general formula (I) which can usefully be used as agonists of the CB2 cannabinoid receptor and hence as drugs active in pathological conditions which can be controlled by stimulation and/or costimulation of this receptor

Abstract: The invention relates to compounds of the general formula (I), as defined, and to pharmaceutical compositions containing them. The compounds of formula (I) are inhibitors of various lipid-related enzymes. They can be used in reducing accumulation of sphingolipids and thus in the treatment of lipid storage diseases. The compounds of formula (I) can also be used for the treatment of cancerous diseases and for killing of wild type and drug-resistant cancer cells.

Abstract: This invention discloses a substance which is a betaine ester of a functional alcohol that has an amido bond in its molecule and releases the functional alcohol.

Abstract: This invention features permeability enhancer molecules, and methods, to increase membrane permeability of various molecules, such as nucleic acids, polynucleotides, oligonucleotides, enzymatic nucleic acid molecules, antisense nucleic acid molecules, 2-5A antisense chimeras, triplex forming oligonucleotides, decoy RNAs, dsRNAs, siRNAs, aptamers, or antisense nucleic acids containing nucleic acid cleaving chemical groups, peptides, polypeptides, proteins, carbohydrates, steroids, metals and small molecules, thereby facilitating cellular uptake of such molecules.

Abstract: This invention discloses a substance which is a betaine ester of a functional alcohol that has an amido bond in its molecule and releases the functional alcohol.

Abstract: This invention provides a hydroxyl group-containing betaine compound and a long-chain alkyl group-containing betaine compound, both of which are highly biodegradable and useful as surfactants, bactericides, antistatic agents, softening agents, rust inhibitors, resin modifiers, synthetic intermediates, etc. The invention further provides processes for producing such betaine compounds.

Abstract: The present invention relates to a method for preparing a cationic surfactant in which physical chemical characteristics such as softness, antistatic properties, etc. as well as biodegradability are quite excellent due to having an ester group and a hydrophilic hydroxyl group in its molecules. A cationic surfactant of the present invention is prepared by reacting tertiary amine drivatives, fatty acid, and epihalohydrin, and prepared simply by reacting esterification and quaternary reactions in one step with a high yield. The above cationic surfactant is a high grade alkyl quaternary ammonium compound as represented in General Formula (1), wherein R1 is a C1-C4 alkyl group; R2 is a C7-C21 linear or branched alkyl or alkenyl group; A is OCOR3, NHCOR3 or OH; R3 is a C7-C21 linear or branched alkyl or alkenyl group; X is a halogen atom; and n is an integral number from 2 to 6.

Abstract: Quaternized monoalkyl compounds derived from fatty acids are described. The quats are produced from fatty acid materials which contain at least about 30% by weight of larger chains containing at least 20 carbons in length. Personal care products produced using these quats are also described.

Abstract: Dialkyl quats useful in personal care products are described. These quats are produced from fatty acids at least 30% by weight of which are C-20 in length or longer.

Abstract: The present invention provides novel amide-based cationic lipids of the general structure: or a salt, or solvate, or enantiomers thereof wherein; (a) Y is a direct link or an alkylene of 1 to about 20 carbon atoms; (b) R1 is H or a lipophilic moiety; (c) R2, R3, and R4 are positively charged moieties, or at least one but not all of R2,R3, or R4 is a positive moiety and the remaining are independently selected from H, an alkyl moiety of 1 to about 6 carbon atoms, or a heterocyclic moiety of about 5 to about 10 carbon atoms; (d) n and p are independently selected integers from 0 to 8, such that the sum of n and o is from 1 to 16; (e) X− is an anion or polyanion and (f) m is an integer from 0 to a number equivalent to the positive charge(s) present on the lipid; provided that if Y is a direct link and the sum of n and p is 1 then one of either R3 or R4 must have an alkyl moiety of at least 10 carbon atoms.

Abstract: Aqueous-alcoholic solutions of coconut or palm oil alkylamidopropylbetaines with a betaine content of greater than 50%, which are fluid, stable and pumpable are described as occupying a well-defined zone of their betaine/water/ethanol ternary diagram. They are prepared by synthesis and quaternization of the amidoamine directly in the solvent medium in which they are defined.

Abstract: Aqueous-alcoholic solutions of hydrogenated coconut or palm kernel oil alkylamidopropylbetaines with a betaine content of greater than 50%, which are fluid, stable and pumpable are described as occupying a well-defined zone of their betaine/water/ethanol ternary diagram. They are prepared by synthesis and quaternization of the amidoamine directly in the solvent medium in which they are defined.

Abstract: The present invention is directed to free radical polymers, which contain a meadowfoam ester group as one of the functional groups polymerized. The compounds of the invention are prepared by the free radical polymerization of a novel meadowfoam monomer having a reactive vinyl group and a number of other free radical polymerizable reactants. The unique structure of the meadowfoam results in polymers with oxidative stability heretofore unattainable.

Abstract: The invention relates to amino acid derivatives of general formula (I), wherein R1 is H or CH3, X is H or NR2R3, wherein R2 is H, CH3, COH or COCH3 and R3 is H, CH3 or COO—Z wherein Z is R2R3 NH+CHR1(CH2)nCOO(CH2)mCH2Y; Y is H, CH3 or NHR4, wherein R4 a COO—NH3+CH2(CH2)mOOC(CH2)nCH3, the meaning of group (CH2)m being selected from alkyls, secondary alkyls, monocycloalkyls, bicycloalkyls and tricycloalkyls having from 4 to 15 carbon atoms and n having a value of from 3 to 14.

Abstract: The present invention relates to a series of novel glyceryl phosphobetaine compounds which are exceptional f surface active agents that provide outstanding foam and are very mild to the hair and skin. The compounds, because they contain a pendant ionizable phosphate group and a quaternary amine compound are amphoteric surfactants that is they contain both a positive and negative charge in the same molecule. These combination of properties makes these polymers ideally suited for use in personal care applications.

Abstract: The invention relates to high-foaming zwitterionic and anionic surfactants which are prepared by sulfation of N,N-dialkylaminoalkyl-sugar amides, preferably using gaseous sulfur trioxide. The invention furthermore relates to compositions which comprise known surfactants and suitable solvents, in addition to the novel active compounds. The novel surfactants are particularly suitable for detergents and cosmetic formulations.

Abstract: Amphoteric derivatives of aliphatic polyamines, such as diethylenetriamine or triethylenetetramine reacted with long chain fatty acids, esters or triglycerides from various natural or synthetic sources are effective in the softening/texture modification of substrates such as paper, textiles, human skin surfaces and hair tresses, as well as in applications for metal working and lubrication. The polyamines are first reacted with fatty acids, esters or triglycerides derived from various animal, vegetable or synthetic sources ranging in molecular distribution from butyric through erucic acids (e.g. milkfat, soy bean oil, rapeseed oil) to form polyamines or imidazolines; they are then further reacted with unsaturated or halogenated carboxylic acids, carboxylated epoxy compounds or acid anhydrides (e.g. acrylic acid, itaconic acid, chloroacetic acid, maleic anhydrides octadecenyl anhydride) to form the various amphoteric structures.

Abstract: Disclosed herein are inhibitors of the multicatalytic protease enzyme which are represented by the general formula: ##STR1## Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.

Abstract: The invention relates to a process for the preparation of highly concentrated free-flowing and pumpable aqueous solutions of betaines by quaternization of a compound which contains tertiary amine nitrogen with a .omega.-halo carboxylic acid characterized in that 0.5-5% by weight of the final product, of a viscosity-reducing compound such as an alkali or alkaline earth metal citric acid salt is added to the reaction mixture before or during the quaternization reaction.

Abstract: The present invention deals with the composition of matter and the utilization of certain novel meadowfoam based quaternary compounds. These materials are useful in personal care applications as hair conditioners.

Abstract: The present invention deals with the composition of matter and the utilization of certain novel guerbet based quat compounds. These materials are useful in personal care applications.

Abstract: Amidopropyl-N-alkyl-polyhydroxyalkylamines of the following formula (1) ##STR1## in which Z is a linear polyhydroxyhydrocarbon radical having at least 2 free or oxyalkylated hydroxyl groups, R.sup.1 is a C.sub.1 to C.sub.7 -alkyl radical or C.sub.2 to C.sub.4 -hydroxyalkyl radical and COR is an aliphatic acyl radical having 6 to 22 carbon atoms, and salts thereof from an inorganic or organic acid are described. They are prepared by a) reaction of a compound of the formula (2) ##STR2## with acrylonitrile to give the compound of the formula (3) ##STR3## b) hydrogenation of the product obtained in step a) to give the compound of the formula (4) ##STR4## and c) monoacylation of the product obtained in step b) in the melt to give the compound of the formula (1) mentioned. The compounds according to the invention are readily soluble in water and water/alcohol mixtures and are advantageous co-surfactants for use in detergents and cleaning compositions and in cosmetic preparations for cleansing the hair and skin.

Abstract: The present invention deals with the composition of matter and the utilization of certain novel amido amine salts of meadowfoam amido propyl dimethyl amine. These materials are useful in personal care applications.

Abstract: A new compound, Denatonium Capsaicinate, and a method of producing the same are disclosed. Denatonium Capsaicinate provides an enhanced bitter and/or spicy, pungent flavor and may be used as an aversive agent, biocide, antifoulant and flavorant, for example. It is formed by reaction of a denatonium compound, Lidocaine or Lidocaine derivative with Capsaicin or a derivative thereof.

Abstract: The betaine compounds described correspond to the following formula (1) ##STR1## in which RCO is an aliphatic acyl radical having 6 to 22 carbon atoms, Z is a linear polyhydroxyhydrocarbon radical having at least 3 optionally oxyalkylated hydroxyl groups, m is an integer from 1 to 4, n is an integer from 1 to 4, R.sup.1 is C.sub.1 to C.sub.4 -alkyl or C.sub.2 to C.sub.4 -hydroxyalkyl and R.sup.2 is C.sub.1 to C.sub.4 -alkyl or C.sub.2 to C.sub.4 -hydroxyalkyl. The betaine compounds and the aqueous, alcoholic or aqueous-alcoholic solutions or dispersions thereof are prepared by betainization of a corresponding tertiary amine compound with a halogenocarboxylic acid or a halogenocarboxylic acid salt. The novel betaine compounds and their solutions are suitable, in particular, for the preparation of surface-active compositions for hair and body care.

Abstract: A novel complex containing an ampholytic and/or semi-polar surfactant as well as a higher fatty acid, and if necessary, a clay mineral, and an emulsified composition containing this complex.