Nitrogen Containing (e.g., Sulfonamide Containing, Etc.) Patents (Class 554/94)
  • Publication number: 20130040884
    Abstract: Novel polypeptide derivatives having protracted profile of action.
    Type: Application
    Filed: March 22, 2012
    Publication date: February 14, 2013
    Inventors: Jesper Lau, Thomas Kruse Hansen, Kjeld Madsen, Paw Bloch, Florencio Zaragoza Dorwald, Nils Langeland Johansen
  • Publication number: 20120142951
    Abstract: The invention provides a method for the preparation of ?-sulfo fatty acid alkylester alkanolamine salt comprising: sulfonating a fatty acid alkyl ester to obtain a sulfonated product, reacting an alcohol and a hydrogen peroxide with the sulfonated product to obtain a reactive product, adding an aqueous alkanolamine solution to the resultant reactive product to obtain a neutralized product having a pH of 2 to 6.5; condensing the neutralized product to obtain an aqueous paste containing ?-sulfo fatty acid alkylester alkanolamine salt. According to the present invention, color deterioration can be inhibited at the time of condensation during preparation of alkanolamine salt of ?-sulfo fatty acid alkylester.
    Type: Application
    Filed: April 7, 2010
    Publication date: June 7, 2012
    Inventors: Hideo Andoh, Mikako Sakurai
  • Publication number: 20090291864
    Abstract: The present invention provides aqueous viscoelastic compositions comprising a cleavable anionic surfactant which is a sulphonate and possibly also an electrolyte. The cleavable surfactants useful in the present invention comprise a chemical bond, which is capable of being broken under appropriate conditions, to produce oil soluble and water soluble products typically having no interfacial properties and surface activity compared with the original surfactant molecule. Further, the rheological properties of the aqueous viscoelastic composition are usually altered upon cleavage of the cleavable surfactant generally resulting in the elimination of the viscosifying, viscoelastic and surfactant properties of the composition. Aqueous viscoelastic compositions in accordance with the present invention are suitable for use in oil-field applications, particularly for hydraulic fracturing of subterranean formations.
    Type: Application
    Filed: May 15, 2009
    Publication date: November 26, 2009
    Applicant: Schlumberger Technology Corporation
    Inventors: Robert Seth Hartshorne, Trevor Lloyd Hughes, Timothy Gareth John Jones, Gary John Tustin, Jian Zhou
  • Publication number: 20090264525
    Abstract: The present invention relates to fatty acid esters of polyols or sulfonated fatty acid esters or sulfonated fatty acid amides containing at least one group Y, where Y stands for CF3—(CH2)a—O—, SF5—, CF3—(CH2)a—S—, CF3CF2S—, [CF3—(CH2)a]2N— or [CF3—(CH2)a]NH—, where a stands for an integer selected from the range from 0 to 5, or formula (I), where Rf stands for CF3—(CH2)r—, CF3—(CH2)r—O—, CF3—(CH2)r—S—, CF3CF2—S—, SF5—(CH2)t— or [CF3—(CH2)r]2N—, [CF3—(CH2)r]NH— or (CF3)2N—(CH2)r—, B stands for a single bond, O, NH, NR, CH2, C(O)—O, C(O), S, CH2—O, O—C(O), N—C(O), C(O)—N, O—C(O)—N, N—C(O)—N, O—SO2 or SO2—O, R stands for alkyl having 1 to 4 C atoms, b stands for 0 or 1 and c stands for 0 or 1, q stands for 0 or 1, where at least one radical from b and q stands for 1, and r stands for 0, 1, 2, 3, 4 or 5, to processes for the preparation of these compounds, and to uses of these surface-active compounds.
    Type: Application
    Filed: July 2, 2007
    Publication date: October 22, 2009
    Applicant: MERCK PATENT GMBH
    Inventors: Wolfgang Hierse, Nikolai (Mykola) Ignatyev, Martin Seidel, Elvira Montenegro, Peer Kirsch, Andreas Bathe
  • Patent number: 7420071
    Abstract: There are provided novel thermally stable surfactants for use with fillers in the preparation of polymer composites and nanocomposites. Typically, surfactants of the invention are urethanes, ureas or esters of thiocarbamic acid having a hydrocarbyl group of from 10 to 50 carbons and optionally including an ionizable or charged group (e.g., carboxyl group or quaternary amine). Thus, there are provided surfactants having Formula I: wherein the variables are as defined herein. Further provided are methods of making thermally stable surfactants and compositions, including composites and nanocomposites, using fillers coated with the surfactants.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: September 2, 2008
    Assignee: UChicago Argonne, LLC
    Inventor: David J. Chaiko
  • Patent number: 6344435
    Abstract: The present invention is a detergent composition which contains alkali metal N-methyltaurate, alkali metal taurate or alkali metal hypotaurate salt of a specific organic acid or organic alkali N-methyltaurate, organic alkali taurate or organic alkali hypotaurate salt of a specific organic acid. The detergent composition of the present invention is an excellent detergent composition which has better foaming and foam quality, less pH dependence of the foaming, creamy foam, no creaking feeling or stretched feeling and no offensive odor.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: February 5, 2002
    Assignee: Shiseido Co., Ltd.
    Inventors: Reiji Miyahara, Koji Abe, Keiichi Uehara, Toshio Fukuda, Takahiro Akutsu
  • Patent number: 6323363
    Abstract: The invention concerns amphiphilic compounds of general formula (I) with at least two hydrophilic and at least two hydrophobic groups based on dicarboxylic acid diamides. The disclosed amphiphilic compounds mostly have a surfactant activity and are useful as emulsifiers, demulsifiers, detergents, dispersants, and hydrotropic agents for industry and household, for example in the fields of metal working, ore mining, surface finishing, washing and cleaning, cosmetics, medicine, foodstuff processing and preparation.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: November 27, 2001
    Assignee: RWE-DEA Aktiengesellschaft fuer Mineraloel und Chemie
    Inventors: Klaus Kwetkat, Ulrike Jacobs, Silvia Scholz
  • Patent number: 6180667
    Abstract: Esters of alkanoyl L-carnitines wherein the alkanoyl is a saturated or unsaturated, staight or branched alkanoyl having 2-26 carbon atoms, optionally &ohgr;-substituted with trialkylammonium, dialkylsulfonium, hydroxyl, carboxyl, halogen, methanesulfonyl and hydroxysulfonyl, are useful for preparing pharmaceutical compositions for the treatment of endotoxic shock.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: January 30, 2001
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Piero Foresta, Vito Ruggiero, Maria Ornella Tinti, Nazareno Scafetta
  • Patent number: 6071510
    Abstract: The present invention provides modified amino acids for delivering active agents, and particularly biologically or chemically active agents. The preferred modified amino acids of the present invention include N-acylated or sulfonated amino acids. These modified amino acids are used as carriers to facilitate the delivery of a cargo to a target. Such modified amino acids are well suited to form non-covalent mixtures with biologically-active agents for oral administration to animals. Methods for the preparation and administration of the modified amino acids and compositions including the same are also provided.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: June 6, 2000
    Assignee: Emisphere Technologies, Inc.
    Inventors: Andrea Leone-Bay, Koc-Kan Ho, Jeffery Bruce Press, Nai-Fang Wang
  • Patent number: 5977390
    Abstract: Fluorinated diesters useful for imparting repellency of low surface tension fluids to thermoplastic polymers of formulaeR.sub.f --O--C(O)--(CH.sub.2).sub.n --C(O)--O--R.sub.1 ;R.sub.f --O--C(O)--CH.sub.2 --CH(R.sub.2)--C(O)--O--R.sub.f ;a mixture of R.sub.f --O--C(O)--(CH.sub.2).sub.n --C(O)--O--R.sub.1,R.sub.f --O--C(O)--(CH.sub.2).sub.n --C(O)--R.sub.f, and R.sub.1 --O--C(O)--(CH.sub.2).sub.n --C(O)--O--R.sub.1 ;and [F(CF.sub.2).sub.x CH.sub.2 CH.sub.2 --S--CH.sub.2 ].sub.2 --C--[CH.sub.2 --O--C(O)--C.sub.17 H.sub.35 ].sub.2 ;wherein R.sub.f is F(CF.sub.2).sub.x --(CH.sub.2).sub.m wherein x is 4 to 20 and m is 2 to 6, or F(CF.sub.2).sub.x --SO.sub.2 N(R.sub.3)--R.sub.4 wherein x is 4 to 20; R.sub.1 is a saturated aliphatic hydrocarbon with an average carbon chain length of 12 to 66 carbons; R.sub.2 is a saturated or unsaturated hydrocarbon with 1-20 carbon atoms; R.sub.3 is an alkyl radical having 1 to 4 carbon atoms; R.sub.
    Type: Grant
    Filed: May 14, 1997
    Date of Patent: November 2, 1999
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Kimberly Gheysen Raiford, Theodor Arthur Liss, Edward James Greenwood, Jack Robert Kirchner
  • Patent number: 5659055
    Abstract: Water or lipid soluble, pharmacologically active, antioxidant, anti-phospholipase compounds that are chemically defined. The compounds protect mammalian cells by inhibiting PLA.sub.2 and preventing oxidation. In particular, each compound has at least two fatty moieties and no active hydroxy group. The compound may also have at least one ionizable group, which may be a carboxyl group, and each of the fatty moieties has from sixteen to twenty carbon atoms and at least one cis-unsaturated double bond.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 19, 1997
    Assignee: Virginia Commonwealth University
    Inventors: Richard C. Franson, Raphael M. Ottenbrite
  • Patent number: 5625085
    Abstract: Esters of alkanoyl L-carnitines wherein the alkanoyl is a saturated or unsaturated, straight or branched alkanoyl having 2-26 carbon atoms, optionally .omega.-substituted with trialkylammonium, dialkylsulfonium, hydroxyl, carboxyl, halogen, methanesulfonyl and hydroxysulfonyl, are useful for preparing pharmaceutical compositions for the treatment of endotoxic shock.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: April 29, 1997
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Piero Foresta, Vito Ruggiero, Maria O. Tinti, Nazareno Scafetta
  • Patent number: 5523432
    Abstract: Quaternary ammonium salts of fatty acid hydroxyalkanesulfonic acids are made by reacting a hydroxyalkanesulfonic acid of the formula (I):HO--(C.sub.n H.sub.2n)--SO.sub.3 H (I):wherein n=2 to 4 with a fatty acid having from 6 to 18 carbon atoms at a temperature range of from about 60.degree. C. to about 120.degree. C. and at a reduced pressure followed b reaction with an amine in an organic solvent.
    Type: Grant
    Filed: April 7, 1994
    Date of Patent: June 4, 1996
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Hans-Christian Raths, Rainer Rueben, Manfred Biermann, Timothy J. Cassady
  • Patent number: 5344949
    Abstract: Surface active anion-cation complexes are synthesized where an organic or organosilicon compound with at least one epoxide group is reacted with a quaternary ammonium hydrogen sulfite of the general formulaHN.sup.+ (R.sup.1).sub.3 SO.sub.3 H.sup.- IwhereinR.sup.1 within the molecule is the same or different and can be(1) an alkyl or hydroxyalkyl group with 1 to 18 carbon atoms,(2) a phenyl group, or(3) a group of the formula C.sub.n H.sub.2n+1 CONH--(CH.sub.2).sub.m --, in which n can be a number from 7 to 17 and m is 2 or 3,in the presence of a polar solvent in such amounts so that the molar ratio of the epoxide group to HN.sup.+ (R.sup.1).sub.3 SO.sub.3 H.sup.- is 2:1.
    Type: Grant
    Filed: July 14, 1993
    Date of Patent: September 6, 1994
    Assignee: Th. Goldschmidt AG
    Inventors: Gotz Koerner, Klaus-Dieter Klein, Dietmar Schaefer
  • Patent number: 5312934
    Abstract: Polyhydroxy fatty acid amide nonionic surfactants are converted in high yields to their sulfated analog surfactants using an SO.sub.3 /pyridine complex as a sulfating agent. Thus, C.sub.12 -C.sub.18 N-methyl glucamide is sulfated in methylene chloride or pyridine solvent to form the corresponding sulfated glucamide in yields of 80% or higher.
    Type: Grant
    Filed: November 30, 1992
    Date of Patent: May 17, 1994
    Assignee: The Procter & Gamble Company
    Inventor: James C. Letton
  • Patent number: 5292915
    Abstract: The invention relates to compounds containing carbonate groups and carbonyl groups and having the general formula ##STR1## in which R stands for a C.sub.1 -C.sub.4 -alkyl radical, an aryl radical, or a radical R.sup.1, whereR.sup.1 has the following formula ##STR2## in which R.sup.2 to R.sup.6 stand for H, alkyl, OH, O-alkyl, SH, S-alkyl, halogen, N(alkyl).sub.2, or N(alkyl)(aryl) and at least one but not more than three of the radicals R.sup.2 to R.sup.6 stand for a radical of the formula ##STR3## in which A, B and C stand for alkylene, cycloalkylene, oxaalkylene, polyoxaalkylene or arylene, k and l both stand for an integer from 1 to 80, and the end group Z stands for alkyl, aryl, alkoxycarbonyl, alkoxycarbonyloxy, or aryl.These compounds are suitable for use as emulsifiers for dispersions.
    Type: Grant
    Filed: February 4, 1992
    Date of Patent: March 8, 1994
    Assignee: BASF Aktiengesellschaft
    Inventors: Andreas Boettcher, Manfred Schwartz
  • Patent number: 5250076
    Abstract: The use of alkali, ammonium, and/or amine salts of monocarboxylic acid polyoxyalkylester sulfonic acids as low foam surface active agents in aqueous alkaline conditioners for textile fabrics or yarns is described.
    Type: Grant
    Filed: July 11, 1991
    Date of Patent: October 5, 1993
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Ansgar Behler, Bernd Fabry, Bernd Wahle, Hildegard von Delden
  • Patent number: 5145611
    Abstract: Carboxylic acid derivatives of the formula ##STR1## R.sub.1 is alkoxy, alkylthio, alkylsulphinyl, alkulsulphonyl, alkylamino, cycloalkyl, or cycloalkoxy or optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl or arylamino. R.sub.2 is optionally substituted aryl or, when B is alkylene also a hydrogen atom. A is a straight-chained or branched, saturated or unsaturated alkylene containing 3 to 10 carbon atoms which is optionally interrupted by a heteratom attached to a saturated carbon and has a chain length of at least 3 atoms. Y is S(O).sub.n group or oxygen, n being 0, 1 or 2. B is a valency bond or a straight-chained or branched, saturated or unsaturated alkylene containing 1 to 18 carbon atoms. Physiologically acceptable salts, esters and amides thereof are also included. The compounds are useful in the treatment of metabolic diseases.
    Type: Grant
    Filed: January 12, 1988
    Date of Patent: September 8, 1992
    Assignee: Boehringer Mannheim GmbH
    Inventors: Hans P. Wolff, Ernst-Christian Witte, Hans-Frieder Kuehnle