Patent number: 4576647
Abstract: An oleophilic composition comprising a powdery or granular substance having a hydrophilic surface and a surface modifier comprising an aluminum chelate compound of the formula (I): ##STR1## wherein R.sup.1 is selected from hydrogen and C1-6 alkyl, R.sup.2 is selected from methyl and phenyl, R.sup.3 is selected from R.sup.4 --, R.sup.5 O-- and R.sup.6 NH--, A is selected from R.sup.7 O--, R.sup.8 COO--, R.sup.9 SO.sub.3 --, R.sup.10 OSO.sub.3 --, ##STR2## R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11, R.sup.12 and R.sup.13 are C1-22 alkyl or C3-22 alkenyl, aryl, aralkyl or alkylaryl, R.sup.3 may be the same as or different from R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11, R.sup.12 and R.sup.13, with the proviso that at least one of R.sup.3, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.11, R.sup.12, and R.sup.13 is a substituent having at least 8 carbon atoms or a polymerizable alkenyl group, and m=0.5 to 2.7, n=0.3 to 2.5 and m+n=0.8 to 3.
Type:
Grant
Filed:
August 24, 1984
Date of Patent:
March 18, 1986
Assignees:
Kawaken Fine Chemicals Co., Ltd., Ajinomoto Co., Inc.
Inventor:
Noritaka Matsushita
Patent number: 4557871
Abstract: Novel styrene derivatives of the general formula ##STR1## wherein X is hydrogen or halogen, X.sup.1 is halogen, R is hydrogen or methyl, Y is hydroxymethyl, carboxyl, --COOR.sup.1 or --COR.sup.2 wherein R.sup.1 is prenyl, geranyl, farnesyl, cyclohexyl, phthalidyl, straight or branched chain alkyl having 1 to 6 carbon atoms, or said alkyl substituted with hydroxy, methoxy, pyridyl or alkanoyloxy having 2 to 16 carbon atoms, and R.sup.2 is amino, hydroxyamino mono-(or di-)alkylamino in which the alkyl moiety contains 1 or 2 carbon atoms, ethoxycarbonylmethylamino, carboxymethylamino, thiazolylamino, cyclohexylamino, pyridylamino, morpholino, N-methylpiperazino, phenylamino, phenylamino substituted with one or two of halogen, hydroxy, methyl, methoxy, trifluoromethyl or carboxyl at the phenyl ring, and the pharmaceutically acceptable salts thereof when Y is carboxyl are disclosed. These compounds exhibit high and long-lasting anti-inflammatory, analgesic and anti-pyretic activity.
Type:
Grant
Filed:
May 14, 1984
Date of Patent:
December 10, 1985
Assignee:
Taisho Pharmaceutical Co., Ltd.
Inventors:
Katsuo Hatayama, Kensei Yoshikawa, Tatsuhiko Sano, Yutaka Ohuchi, Tomomi Ota, Kazuto Sekiuchi, Kaoru Sota