Hydrogen Or Halogen Bonded Directly To The Heavy Metal Patents (Class 556/23)
  • Patent number: 10808000
    Abstract: The present invention provides a process for the preparation of a complex of formula (I): comprising the step of reacting Pd(diolefin)X2 or PdX2 and PR1R2R3 in a solvent to form the complex of formula (I), wherein the process is carried out in the absence of a base, the molar ratio of Pd(diolefin)X2:PR1R2R3 or PdX2:PR1R2R3 is greater than 1:1.1, up to about 1:2.5; each X is independently a halide; and R1, R2 and R3 are independently selected from the group consisting of tert-butyl and isopropyl.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: October 20, 2020
    Assignee: Johnson Matthey Public Limited Company
    Inventors: William Carole, Thomas Colacot, Carin Seechurn, Thomas Scrase
  • Patent number: 9035081
    Abstract: Methods to make R13P?N—TiCl3 and (1-R2-Indenyl)Ti(N?PR13)Cl2, where R1 is independently selected from C1-30 hydrocarbyl radical which is unsubstituted or further substituted by one or more halogen atom, a C1-8 alkoxy radical, a C6-10 aryl radical, a C6-10 aryloxy radical, an amido radical, a silyl radical, and a germanyl radical; P is phosphorus; N is nitrogen (and bonds to the metal M); R2 is a substituted or unsubstituted alkyl group, a substituted or an unsubstituted aryl group, or a substituted or unsubstituted benzyl group, wherein substituents for the alkyl, aryl or benzyl group are selected from alkyl, aryl, alkoxy, aryloxy, alkylaryl, arylalkyl and halide substituents. The method to make R13P?N—TiCl3 combines a titanium species TiCl3(OR) where R is an alkyl or aromatic group, with a trimethylsilyl phosphinimide compound R13P?N—SiMe3 in the presence of solvent, to give the titanium complex R13P?N—TiCl3.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: May 19, 2015
    Assignee: NOVA Chemicals (International) S.A.
    Inventors: Xiaoliang Gao, Zhiwei He
  • Publication number: 20150005524
    Abstract: Methods to make R13P?N—TiCl3 and (1-R2-Indenyl)Ti(N?PR13)Cl2, where R1 is independently selected from C1-30 hydrocarbyl radical which is unsubstituted or further substituted by one or more halogen atom, a C1-8 alkoxy radical, a C6-10 aryl radical, a C6-10 aryloxy radical, an amido radical, a silyl radical, and a germanyl radical; P is phosphorus; N is nitrogen (and bonds to the metal M); R2 is a substituted or unsubstituted alkyl group, a substituted or an unsubstituted aryl group, or a substituted or unsubstituted benzyl group, wherein substituents for the alkyl, aryl or benzyl group are selected from alkyl, aryl, alkoxy, aryloxy, alkylaryl, arylalkyl and halide substituents. The method to make R13P?N—TiCl3 combines a titanium species TiCl3(OR) where R is an alkyl or aromatic group, with a trimethylsilyl phosphinimide compound R13P?N—SiMe3 in the presence of solvent, to give the titanium complex R13P?N—TiCl3.
    Type: Application
    Filed: May 27, 2014
    Publication date: January 1, 2015
    Applicant: NOVA CHEMICALS (INTERNATIONAL) S.A.
    Inventors: Xiaoliang Gao, Zhiwei He
  • Publication number: 20140323737
    Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru?CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3.
    Type: Application
    Filed: May 1, 2014
    Publication date: October 30, 2014
    Applicant: ELEVANCE RENEWABLE SCIENCES, INC.
    Inventors: Linda A. Kunz, Steven A. Cohen, Melvin L. Luetkens, JR.
  • Patent number: 8816114
    Abstract: The invention is directed to aryl alkylidene ruthenium complexes and the use of these complexes as catalysts in metathesis reactions.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: August 26, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Renat Kadyrov, Anna Christoffers
  • Publication number: 20140213806
    Abstract: The invention describes electronic devices comprising a metal complex compound having at least one ligand contain-ing an N donor and a P donor having the formula (I), in which the carbons C1 and C2 are part of an aromatic or non-aromatic ring system F1, P and N are phosphorus and nitrogen, where the nitrogen is in sp2-hybridised form, the radicals R3 and R4 are, indepen-dently of one another, hydrogen or an alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, cyclo-alkynyl, alkylcycloalkyl, heteroalkyl, heterocycloalkyl, heteroalkylcycloalkyl, aryl, hetero-aryl, aralkyl or heteroaralkyl radical having up to 40 C atoms, and R1 and R2 are, independently of one another, an atom or radical from the group comprising hydrogen, halogen, R, RO—, RS—, RCO—, RCOO—, RNH—, R2N—, RCONR— and —Si(R)X(OR)3-X, where R=an alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, cycloalkynyl, alkylcycloalkyl, heteroalkyl, hetero-cycloalkyl, hetero-alkyl-cycloalkyl, aryl, heteroaryl, aralkyl or heteroaralkyl radical having up to 40 C at
    Type: Application
    Filed: July 19, 2012
    Publication date: July 31, 2014
    Applicant: Merck Patent GmbH
    Inventors: Lars Wesemann, Fritz-Robert Küchle, Hermann August Mayer, Sophie Wernitz, Hartmut Yersin, Markus Leitl
  • Patent number: 8779152
    Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru?CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: July 15, 2014
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Linda A. Kunz, Steven A. Cohen, Melvin L. Luetkens, Jr.
  • Patent number: 8772520
    Abstract: The present invention provides a process for the preparation of a Pd(0)Ln complex, where L is a ligand and n is 2, 3 or 4, comprising the steps of: (a) reacting a Pd(II) complex in at least one solvent with a base and ligand L; and (b) if required, adding further base, optionally in at least one solvent, to form the Pd(0)Ln complex; wherein the at least one solvents in steps a and b are independently the same or different, and provided that when n=2, the Pd(II) complex is not bis[tri(ortho-tolyl)phosphine] palladium chloride. The invention also provides novel Pd(0)L2 and Pd(II) complexes.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: July 8, 2014
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Thomas John Colacot, Gabriela Alexandra Grasa, Hongbo Li
  • Publication number: 20140187803
    Abstract: The invention provides a new method for the preparation of the dimeric Pd(l) tri-tert.-butylphosphine bromide complex, characterized by the chemical formula [Pd(?-Br)(PtBu3)]2. The method is based on a comproportionation reaction in which a Pd(ll) compound (=PdBr2) is reacted with a Pd(0) compound (=Pd(PtBu3)2) in organic solvents to yield the [Pd(?-Br)(PtBu3)]2 compound having the Pd atoms in the formal oxidation state +1. Unreacted PdBr2 may be reused in the process. The method is straightforward and applicable for industrial scale production and provides high product yields. Further, a new process for the isomerization of allyl ethers of the general type R1—C(O)—O—CH(R2)—C(R3)?CH2 employing the compound Pd?-Br)(PtBu3)]2 as a catalyst is disclosed.
    Type: Application
    Filed: June 25, 2012
    Publication date: July 3, 2014
    Applicant: Umicore AG & Co. KG
    Inventors: Lukas Goossen, Matthias Arndt, Patrizia Mamone, Matthias Gruenberg
  • Publication number: 20140186984
    Abstract: The invention describes electronic devices comprising a metal complex compound having at least one tetradentate ligand having N and/or P donors, in particular a ligand having a PPPP, NNNN, PNNP or NPPN structure, and uses of a complex of this type in the electronic field and for the generation of light.
    Type: Application
    Filed: July 18, 2012
    Publication date: July 3, 2014
    Applicant: Merck Patent GmbH
    Inventors: Lars Wesemann, Hartmut Schubert, Hermann August Mayer, Sophie Wornitz
  • Patent number: 8618318
    Abstract: The present invention provides a process for the preparation of a complex of formula (I) comprising the steps of: (a) mixing Pd(diolefin)Br2 and tBu3P in a solvent; and (b) adding an alkali hydroxide to form the complex of formula (I).
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: December 31, 2013
    Assignee: Johnson Matthey Public Limited Co.
    Inventors: Thomas John Colacot, Mark William Hooper, Gabriela Alexandra Grasa
  • Patent number: 8501975
    Abstract: A method of manufacturing ruthenium carbene complexes and novel aryl alkylidene ruthenium complexes based on the method, the complexes able to used as catalysts in metathesis reactions.
    Type: Grant
    Filed: April 8, 2009
    Date of Patent: August 6, 2013
    Assignee: Evonik Degussa GmbH
    Inventors: Renat Kadyrov, Anna Rosiak
  • Publication number: 20130165667
    Abstract: A method for the creation of a carbon-carbon (C—C) bond or of a carbon-heteroatom (C-HE) bond includes reacting a compound carrying a leaving group with a nucleophilic compound carrying a carbon atom or a heteroatom (HE) capable of replacing the leaving group, thus creating a C—C or C-HE bond, in which process the reaction is carried out in the presence of an effective amount of a catalytic system comprising at least one copper/butadienylphosphine complex.
    Type: Application
    Filed: February 26, 2013
    Publication date: June 27, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE SIDI MOHAMMED BEN ABDELLAH, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
    Inventors: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, UNIVERSITE SIDI MOHAMMED BEN ABDELLAH
  • Publication number: 20130096314
    Abstract: A method for preparing a ruthenium carbene complex precursor includes reacting a ruthenium refinery salt with a hydrogen halide to form a ruthenium intermediate, and reacting the ruthenium intermediate with an L-type ligand to form the ruthenium carbene complex precursor. A method for preparing a ruthenium vinylcarbene complex includes converting a ruthenium carbene complex precursor into a ruthenium hydrido halide complex, and reacting the ruthenium hydrido halide complex with a propargyl halide to form the ruthenium vinylcarbene complex. A method for preparing a ruthenium carbene complex includes converting a ruthenium carbene complex precursor into a ruthenium carbene complex having a structure (PR1R2R3)2Cl2Ru?CH—R4, wherein R1, R2, R3, and R4 are alike or different, and wherein covalent bonds may optionally exist between two or more of R1, R2, and R3 and/or two of R1, R2, and R3 taken together may optionally form a ring with phosphorous.
    Type: Application
    Filed: September 7, 2012
    Publication date: April 18, 2013
    Inventors: Linda A. Kunz, Steven A. Cohen
  • Publication number: 20130096090
    Abstract: The present invention relates to the fields of chemistry and pharmaceuticals. Embodiments of the present invention provide transition metal complexes of amino acids. Transition metal complexes of embodiments of the invention according to Categories I, II, III, and/or IV may be used as antimicrobial, anti-malarial, and anti-cancer agents, as well as catalysts in chemical reactions. Such compounds of the invention are particularly useful for combating multi-drug resistance against a broad range of microbials (such as MRSA and mycobacteria), including gram positive and gram negative bacteria, as well as can be used as anti-cancer agents against bladder cancer, breast cancer, colon cancer, rectal cancer, endometrial cancer, kidney cancer, leukemia, lung cancer, melanoma, non-Hodgkin's lymphoma, pancreatic cancer, prostate cancer, and thyroid cancer, to name a few.
    Type: Application
    Filed: October 17, 2012
    Publication date: April 18, 2013
    Applicant: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
    Inventor: Virginia Tech Intellectual Properties, Inc.
  • Patent number: 8361922
    Abstract: The invention relates to ruthenium alkylidene complexes having an N-heterocyclic carbene ligand comprising a 5-membered heterocyclic ring having a carbenic carbon atom and at least one nitrogen atom contained within the 5-membered heterocyclic ring, wherein the nitrogen atom is directly attached to the carbenic carbon atom and is substituted by a phenyl ring, and wherein the phenyl ring has a hydrogen at either or both ortho positions and is substituted at at least one ortho or meta position. The invention also relates to an olefin metathesis reactions and particularly to the preparation of tetra-substituted cyclic olefins via a ring-closing metathesis.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: January 29, 2013
    Assignees: Materia, Inc., California Institute of Technology
    Inventors: Jacob Berlin, Robert H. Grubbs, Yann Schrodi, Ian C. Stewart
  • Patent number: 8299284
    Abstract: A compound having the formula (I) where each of R1, R2, R3 and R4 is independently C6-C18 aryl-, C5-C8 cycloalkyl-, C6-C18 aryl having at least one C1-C20 alkyl substituent, C5-C8 cycloalkyl having at least one C1-C20 alkyl substituent, C4-C20 branched alkyl-, C16-C20 linear alkyl-, RO—, —NRR?, —PRR?, —SR, fluoro substituted forms thereof, and perfluoro forms thereof: and R5 is C6-C18 aryl-, C5-C8 cycloalkyl-, C6-C18 aryl having at least one C1-C20 alkyl substituent, C5-C8 cycloalkyl having at least one C1-C20 alkyl substituent, C3-C20 branched alkyl-, C2-C30 linear alkyl-, fluoro substituted forms thereof, and perfluoro forms thereof; where R and R? are each independently C6-C18aryl-, C5-C8 cycloalkyl-, C6-C18 aryl having at least one C1-C20 alkyl substituent, C5-C8 cycloalkyl having at least one C1-C20 alkyl substituent, C4-C20 branched alkyl-, C2-C30 linear alkyl-, fluoro substituted forms thereof, and perfluoro forms thereof; A is N, P, S, or O with the proviso that when A is S, R2 is a nullify; and M is
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: October 30, 2012
    Assignee: Stephan Consulting Corporation
    Inventors: Douglas W. Stephan, Preston A. Chase, Gregory C. Welch
  • Publication number: 20120190873
    Abstract: The present invention provides a process for the preparation of a complex of formula (I) comprising the steps of: (a) mixing Pd(diolefin)Br2 and tBu3P in a solvent; and (b) adding an alkali hydroxide to form the complex of formula (I).
    Type: Application
    Filed: July 27, 2010
    Publication date: July 26, 2012
    Applicant: JOHNSON MATTHEY PUBLIC LIMITED COMPANY
    Inventors: Thomas John Colacot, Mark William Hooper, Gabriela Alexandra Grasa
  • Publication number: 20120116109
    Abstract: The present invention provides a process for the preparation of a Pd(0)Ln complex, where L is a ligand and n is 2, 3 or 4, comprising the steps of: (a) reacting a Pd(II) complex in at least one solvent with a base and ligand L; and (b) if required, adding further base, optionally in at least one solvent, to form the Pd(0)Ln complex; wherein the at least one solvents in steps a and b are independently the same or different, and provided that when n=2, the Pd(II) complex is not bis[tri(ortho-tolyl)phosphine] palladium chloride. The invention also provides novel Pd(0)L2 and Pd(II) complexes.
    Type: Application
    Filed: January 12, 2010
    Publication date: May 10, 2012
    Applicant: Johnson Matthey Public Limited Company
    Inventors: Thomas John Colacot, Gabriela Alexandra Grasa, Hongbo Li
  • Publication number: 20120046479
    Abstract: The present disclosure relates to a method for preparing a metal catalyst comprising at least one ligand that is coordinated to the metal through at least one phosphorous (P) atom and at least one nitrogen (N) atom, the method comprising reacting a metal pre-cursor complex with an acid ad salt of an aminophosphine, diaminophosphine, aminodiphosphine or diaminodiphosphine, in the presence of a base.
    Type: Application
    Filed: October 8, 2009
    Publication date: February 23, 2012
    Inventors: Kamaluddin Abdur-Rashid, Dino Amoroso, Xuanhua Chen, Rongwei Guo, Shuiming Lu, Chi-Wing Tsang
  • Patent number: 8008224
    Abstract: The invention relates to ruthenium alkylidene complexes having an N-heterocyclic carbene ligand comprising a 5-membered heterocyclic ring having a carbenic carbon atom and at least one nitrogen atom contained within the 5-membered heterocyclic ring, wherein the nitrogen atom is directly attached to the carbenic carbon atom and is substituted by a phenyl ring, and wherein the phenyl ring has a hydrogen at either or both ortho positions and is substituted at at least one ortho or meta position. The invention also relates to an olefin metathesis reactions and particularly to the preparation of tetra-substituted cyclic olefins via a ring-closing metathesis.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: August 30, 2011
    Assignees: Materia, Inc., California Institute of Technology
    Inventors: Jacob Berlin, Robert H. Grubbs, Yann Schrodi, Ian C. Stewart
  • Patent number: 7998895
    Abstract: Transition metal complexes of selected monoanionic phosphine ligands, which also contain a selected Group 15 or 16 (IUPAC) element and which are coordinated to a Group 3 to 11 (IUPAC) transition metal or a lanthanide metal, are polymerization catalysts for the (co)polymerization of olefins such as ethylene and ?-olefins, and the copolymerization of such olefins with polar group-containing olefins. These and other nickel complexes of neutral and monoanionic bidentate ligands copolymerize ethylene and polar comonomers, especially acrylates, at relatively high ethylene pressures and surprisingly high temperatures, and give good incorporation of the polar comonomers and good polymer productivity. These copolymers are often unique structures, which are described.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: August 16, 2011
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Lin Wang, Elisabeth M. Hauptman, Lynda Kaye Johnson, Elizabeth Forrester McCord, Stephan J. McLain, Ying Wang
  • Publication number: 20110040099
    Abstract: A method of manufacturing ruthenium carbene complexes and novel aryl alkylidene ruthenium complexes based on the method, the complexes able to used as catalysts in metathesis reactions.
    Type: Application
    Filed: April 8, 2009
    Publication date: February 17, 2011
    Applicant: Evonik Degussa GmbH
    Inventors: Renat Kadyrov, Anna Rosiak
  • Patent number: 7847126
    Abstract: The invention relates to a process for synthesizing tertiary phosphines by reacting halophosphines with organomagnesium compounds in the presence of copper compounds and optionally of salts.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: December 7, 2010
    Assignee: LANXESS Deutschland GmbH
    Inventors: Florian Rampf, Hans-Christian Militzer
  • Publication number: 20100222577
    Abstract: Novel ?-diimine metal complexes, particularly iron complexes, having a phenyl sulfidyl or substituted phenyl sulfidyl metal complexing group are disclosed. The ?-diimine metal complexes having a phenyl sulfidyl or substituted phenyl sulfidyl metal complexing group are produced by forming one of the ?-diimine metal complex imine bonds in the presence of a metal salt or an ?-acylimine metal complex. The ?-diimine metal complexes having phenyl sulfidyl or substituted phenyl sulfidyl metal complexing group are useful for polymerizing or oligomerizing olefins.
    Type: Application
    Filed: May 7, 2010
    Publication date: September 2, 2010
    Applicant: CHEVRON PHILLIPS CHEMICAL COMPANY LP
    Inventors: Brooke L. Small, Michael Carney
  • Patent number: 7759439
    Abstract: A method of controlling the molecular weight of poly(cyclic)olefin (norbornene-type) polymers and activating the polymerization thereof with a single material is provided. Such method include adding a chain transfer/activating agent to a mixture of monomer(s), catalyst, solvent and an optional cocatalyst and polymerizing the mixture to form a polymer. It is shown that the amount of chain transfer/activating agent in the mixture can serve to control the molecular weight of the resulting polymer, its percent conversion or both, and in some embodiments the optical density of the resulting polymer.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: July 20, 2010
    Assignee: Promerus LLC
    Inventors: Larry F. Rhodes, Steven Smith, Pramod Kandanarachchi, Chun Chang, Patrick Bradley
  • Publication number: 20100179323
    Abstract: A process for making diphosphine-ruthenium-diamine complexes by reacting a phosphine compound with an arene ruthenium compound in a first solvent to produce an intermediate mixture comprising a diphosphine-ruthenium compound, the first solvent consisting essentially of a mixture of an aprotic solvent and a protic solvent; then removing the first solvent from the intermediate mixture to produce an intermediate solid comprising the diphosphine-ruthenium compound; and then contacting the intermediate solid comprising the diphosphine-ruthenium compound with a diamine and a second solvent to produce the diphosphine-ruthenium-diamine complex, the second solvent consisting essentially of an aprotic solvent selected from the group consisting of ethers and hydrocarbon solvents.
    Type: Application
    Filed: June 28, 2006
    Publication date: July 15, 2010
    Inventor: Paul H Moran
  • Patent number: 7728160
    Abstract: Novel ?-diimine metal complexes, particularly iron complexes are disclosed. The ?-diimine metal complexes are produced by forming one of the ?-diimine metal complex imine bonds in the presence of a metal salt or an ?-acylimine metal complex. ?-diimine metal complexes having two different ?-diimine nitrogen groups may be produced. The ?-diimine metal complexes are useful for polymerizing or oligomerizing olefins.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: June 1, 2010
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Brooke L. Small, Michael Carney
  • Patent number: 7728161
    Abstract: Methods for making ?-diimine metal complexes are described. The methods comprise forming an ?-diimine metal complex imine bond in the presence of a metal salt or an ?-acylimine metal complex. The method is particularly using for the production of ?-diimine metal complexes having two different ?-diimine nitrogen groups. The ?-diimine metal complexes are useful for polymerizing or oligomerizing olefins.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: June 1, 2010
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Brooke L. Small, Michael Carney
  • Publication number: 20100121076
    Abstract: The present invention relates to a method for preparing phosphine butadiene-type ligands, and their use, particularly as catalytic metal ligands used in the reactions leading to the formation of carbon-carbon and carbon-heteroatom bonds.
    Type: Application
    Filed: April 21, 2008
    Publication date: May 13, 2010
    Applicants: Centre National De La Recherche Scientifique (C.N.R.S.), Ecole Nationale Superieure De Chimie De Montpellier, Universite Sidi Mohammed Ben Abdellah
    Inventors: Marc Taillefer, Hamid Kaddouri, Fouad Ouazzani, Armelle Ouali
  • Patent number: 7642357
    Abstract: The present invention has as its object to provide an iridium complex represented by the general formula: [(I r H L1 L2)2(??X1)(??X2)(??X3)]X4??(1) (wherein L1 and L2 may be the same or different and each represent a monodendate neutral ligand, or each cooperate with the other to form a bidendate neutral ligand; X1, X2 and X3 may be the same or different, and each represent a halogen atom; and X4 is a counter-anion). Also, the present invention provides a novel catalyst which can achieve excellent performance as a catalyst for asymmetric synthesis, especially asymmetric hydrogenation, in terms of chemical selectivity, enantioselectivity and catalytic activity, and the like.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: January 5, 2010
    Assignee: Takasago International Corporation
    Inventors: Kazushi Mashima, Tsuneaki Yamagata
  • Publication number: 20090036696
    Abstract: The present invention has as its object to provide an iridium complex represented by the general formula: [(l r H L1 L2)2(?-X1)(?-X2)(?-X3)]X4??(1) (wherein L1 and L2 may be the same or different and each represent a monodendate neutral ligand, or each cooperate with the other to form a bidendate neutral ligand; X1, X2 and X3 may be the same or different, and each represent a halogen atom; and X4 is a counter-anion). Also, the present invention provides a novel catalyst which can achieve excellent performance as a catalyst for asymmetric synthesis, especially asymmetric hydrogenation, in terms of chemical selectivity, enantioselectivity and catalytic activity, and the like.
    Type: Application
    Filed: August 27, 2004
    Publication date: February 5, 2009
    Inventors: Kazushi Mashima, Tsuneaki Yamagata
  • Patent number: 7361776
    Abstract: The present invention relates to a zero-valent transition metal complex which can be used as a starting material for producing a catalyst usable for producing a polyolefin by ring-opening metathesis polymerization of an olefin and an epothilone by ring-closing metathesis reaction, and a method for efficiently producing, at low cost, an organometallic compound useful as a catalyst, using the zero-valent transition metal complex as a starting material. Provided is a method for producing a zero-valent transition metal complex (C), which comprises reacting a divalent transition metal complex (A) with an olefin (B), the complex (A) being selected from the group consisting of a divalent ruthenium complex (A1) and a divalent osmium complex (A2), thereby obtaining a zero-valent transition metal complex (C), wherein the reaction is conducted under reducing conditions and after the reaction, the resultant crude product is extracted at high temperature using a saturated hydrocarbon as an extracting solvent.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: April 22, 2008
    Assignee: Sekisui Chemical Co., Ltd.
    Inventors: Hiroshi Hiraike, Takeharu Morita, Fumiyuki Ozawa, Hiroyuki Katayama
  • Patent number: 7276616
    Abstract: The use of a phosphorus containing Ligand as a Ligand for a metathesis catalyst in a catalysed metathesis reaction wherein the phosphorus containing Ligand is a heterocyclic organic compound with a ligating phosphorus atom as an atom in the heterocyclic ring structure of the heterocyclic organic compound. The invention also relates to a metathesis catalyst such a phosphorus containing Ligand and to a metathesis reaction using the catalyst.
    Type: Grant
    Filed: July 4, 2003
    Date of Patent: October 2, 2007
    Assignee: Sasol Technology (UK) Limited
    Inventors: Catherine Lynn Dwyer, Ann Elizabeth Catherine McConnell, Grant Stephen Forman
  • Patent number: 7271121
    Abstract: Methods for making ?-diimine metal complexes are described. The methods comprise forming an ?-diimine metal complex imine bond in the presence of a metal salt or an ?-acylimine metal complex. The method is particularly using for the production of ?-diimine metal complexes having two different ?-diimine nitrogen groups. The ?-diimine metal complexes are useful for polymerizing or oligomerizing olefins.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: September 18, 2007
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Brooke L. Small, Michael Carney
  • Patent number: 7268096
    Abstract: Novel ?-diimine metal complexes, particularly iron complexes are disclosed. The ?-diimine metal complexes are produced by forming one of the ?-diimine metal complex imine bonds in the presence of a metal salt or an ?-acylimine metal complex. ?-diimine metal complexes having two different ?-diimine nitrogen groups may be produced. The ?-diimine metal complexes are useful for polymerizing or oligomerizing olefins.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: September 11, 2007
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Brooke L. Small, Michael Carney
  • Patent number: 7198730
    Abstract: A luminescent organometallic complex composition of matter, a method of preparing this composition of matter, and an electronic device built with this composition of matter. The composition includes: at least one transition metal that produces phosphorescent emission at room temperature, at least one first monoanionic bidentate ligand coordinated through a nitrogen on a heteroaromatic ring and a carbon, and at least one second ligand selected from a hydride and a ligand coordinated through a carbon atom which is part of an aromatic group.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: April 3, 2007
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Norman Herron, Nora Sabina Radu, Eric Maurice Smith, Ying Wang
  • Patent number: 7101959
    Abstract: A subject of the present invention is new compounds having a lanthanide and having a tridentate ligand, a process for their preparation and their use in particular as polymerization catalysts.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: September 5, 2006
    Assignees: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Anca Dumitrescu, Heinz Gornitzka, Blanca Martin-Vaca, Didier Bourissou, Guy Bertrand, Jean-Bernard Cazaux
  • Patent number: 7094898
    Abstract: A new class of compounds is disclosed that in preferred embodiments relate to Ru-based catalysts suitable for use in olefin metathesis reactions. Such compounds demonstrate high rates of catalytic turnover in comparison with other Ru catalysts known in the art. Moreover, the catalysts are highly stable, and readily suited to attachment to a solid support via the anionic ligands. The invention also pertains to methods of producing the catalysts, and their use in catalyzing olefin metathesis reactions.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: August 22, 2006
    Assignee: University of Ottawa
    Inventors: Deryn Elizabeth Fogg, Jay Christopher Conrad
  • Patent number: 7081533
    Abstract: The present invention concerns novel unsymmetrical chiral diphosphines of a mixed aliphatic-aromatic type and processes for synthesizing them, complexes of these compounds and their use as catalysts.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 25, 2006
    Assignee: Degussa AG
    Inventors: Boris E Bosch, Axel Monsees, Uwe Dingerdissen, Paul Knochel, Eike Hupe
  • Patent number: 7019158
    Abstract: Chiral organometallic compounds are provided which comprise certain non-symmetrically substituted cyclopentadiene complexed to a transition metal. The cyclopentadiene has a second coordinating group which also complexes the transition metal and is attached to the cyclopentadiene by means of a chiral connecting chain. Preferred transition metals include rhodium, ruthenium, iridium, cobalt, iron, manganese, chromium, tungsten, molybdenum, nickel, palladium, or platinum. These chiral organometallic compounds find use in asymmetric synthesis to produce chiral compounds.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: March 28, 2006
    Assignee: Avecia Limited
    Inventor: Richard John Whitby
  • Patent number: 6927262
    Abstract: The invention relates to novel bridged biphosphole ligands according to the general formula: where R2, R3, R4 are chosen from hydrogen, alkyl, aryl or silyl, R1 is chosen from hydrogen, alkyl, aryl or halogen, R1 possibly being replaced with a direct bond between the two phosphorus atoms and T is a divalent group. The invention also relates to metallocenes obtained from these ligands. These metallocenes are useful as catalytic components for the polymerization of olefins.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: August 9, 2005
    Assignee: Atofina
    Inventors: Francois-Xavier Buzin, Francois Nief, Francois Mathey, Jean Malinge, Eliane Deschamps, Bernard Deschamps
  • Patent number: 6909009
    Abstract: Novel polynuclear organometallic complexes useful as catalysts for the reversible deshydrogenation of alkanes and alkane group are disclosed. The novel compounds comprise a first transition, a second transition metal p-bonded to an ?5-aromatic ligand, and a pincer ligand. The pincer ligand comprises a 6p-electron aromatic ring having at least 2 ring atoms in an 1, 3 relationship bonded each to a neutral Lewis base through a bridge, the bridge being a diradical. The pincer ligand binds the first transition metal through each of the Lewis bases and through the ring atom adjacent to both Lewis bases and p-coordinates the second transition metal through all aromatic ring atoms. The first transition metal may also bond to 2 or 4 hydrogen atoms.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: June 21, 2005
    Inventor: Avtandil Koridze
  • Patent number: 6888017
    Abstract: This invention relates to bridged indenyl metallocene compositions and their use in the preparation of catalyst systems for olefin polymerization, particularly propylene polymerization. The bridge may be represented by the formula: wherein: R17 to R24 are identical or different, and are one of a hydrogen atom, a C1-C10 alkyl group, a C1-C10 alkoxy group, a C6-C10 aryl group, a C6-C10 aryloxy group, a C2-C10 alkenyl group, a C7-C40 arylalkyl group, a C7-C40 alkylaryl group, a C8-C40 arylalkenyl group, or a halogen atom, or together are a conjugated diene which is optionally substituted with one or more hydrocarbyl, tri(hydrocarbyl)silyl groups or hydrocarbyl, tri(hydrocarbyl)silylhydrocarbyl groups, said diene having up to 30 atoms not counting hydrogen; or two or more adjacent radicals R17 to R24, including R20 and R21, together with the atoms connecting them form one or more rings; and M2 is carbon, silicon, germanium or tin.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: May 3, 2005
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Matthew C. Kuchta, Udo M. Stehling, Robert T. Li, William T. Haygood, Jr., Terry J. Burkhardt
  • Patent number: 6887820
    Abstract: A method for producing optically active compounds is disclosed. The method is highly practical for producing optically active compounds useful for various utilities such as intermediates for synthesizing pharmaceutical agents, liquid crystal materials and agents for optical resolution.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: May 3, 2005
    Assignees: Japan Science and Technology Corporation, NKK Corporation, Takeda Pharmaceutical Company Limited, Asahi Kasei Pharma Corporation, Takasago International Corporation
    Inventors: Takao Ikariya, Shohei Hashiguchi, Jun Takehara, Nobuyuki Uematsu, Kazuhiko Matsumura, Ryoji Noyori, Akio Fujii
  • Patent number: 6884859
    Abstract: A method is provided for synthesizing a polymer in a controlled fashion using a ring-opening metathesis polymerization (ROMP) reaction, wherein polymerization is carried out using a catalytically effective amount of an olefin metathesis catalyst and a bridged bicyclic or polycyclic olefin monomer that contains at least two heteroatoms directly or indirectly linked to each other. Preferred catalysts are Group 8 transition metal complexes, particularly complexes of Ru and Os. Such complexes include the ruthenium bisphosphine complex (PCy3)2(Cl)2Ru?CHPh (1) and the ruthenium carbene complex (IMesH2)(PCy3)(Cl)2Ru?CHPh (2). The invention also provides novel regioregular polymers synthesized using the aforementioned methodology, wherein the polymers may be saturated, unsaturated, protected, and/or telechelic. An exemplary polymer is poly((vinyl alcohol)2-alt-methylene)(MVOH).
    Type: Grant
    Filed: August 29, 2002
    Date of Patent: April 26, 2005
    Assignee: California Institute of Technology
    Inventors: Robert H. Grubbs, Oren A. Scherman, Hyunjin M. Kim
  • Patent number: 6878665
    Abstract: The invention relates to novel diphosphines, in optically pure or racemic form, of formula (I): in which: R1 and R2 are a (C5-C7)cycloalkyl group, an optionally substituted phenyl group or a 5-membered heteroaryl group; and A is (CH2—CH2) or CF2. The invention further relates to the use of a compound of formula (I) as a ligand for the preparation of a metal complex useful as a chiral catalyst in asymmetric catalysis, and to the chiral metal catalysts comprising at least one ligand of formula (I).
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: April 12, 2005
    Assignee: Synkem
    Inventors: Sébastien Duprat de Paule, Nicolas Champion, Virginie Vidal, Jean-Pierre Genet, Philippe Dellis
  • Patent number: 6844442
    Abstract: The present invention provides a process for preparing a metal carbene complex of formula (I): wherein M is a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium; L denotes neutral donor ligands ligated to said metal, such groups being the same or different; X is an anionic ligand; R1 and R2 are each independently selected from the group consisting of hydrogen, substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted vinyl, a is 2 or 3 and b is 1 or 2, such process comprising reacting a sulfur ylide of the formula Ar2S?CR1R2 or its precursor with an appropriate metal complex comprising a transition metal atom selected from the group consisting of ruthenium, rhodium, iron, cobalt, osmium and iridium, said metal complex being also
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: January 18, 2005
    Assignee: Yeda Research and Development Company, Ltd.
    Inventors: David Milstein, Mark Gandelman, Nissan Ashkenazi, Boris Rybtchinski
  • Patent number: 6800701
    Abstract: Compounds and metal complexes comprising a polycyclic, fused ring ligand or inertly substituted derivative thereof having up to 60 atoms other than hydrogen, said ligand comprising at least: (1) a cyclopentadienyl ring, (2) a 6, 7, or 8 membered ring other than a 6-carbon aromatic ring, and (3) an aromatic ring, with the proviso that said 6, 7, or 8 membered ring (2), is fused to both the cyclopentadienyl ring (1), and the aromatic ring (3), polymerization catalysts, a process to prepare the novel compounds and complexes, and olefin polymerization processes using the same are disclosed.
    Type: Grant
    Filed: May 13, 2003
    Date of Patent: October 5, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Richard E. Campbell, Jr., Jerzy Klosin, Ravi B. Shankar, Francis J. Timmers, Robert K. Rosen
  • Patent number: 6794525
    Abstract: An (R) or (S) chiral diphosphine of formula (I): wherein R and R1, which can be identical or different, represent an optionally saturated C1-10 alkyl group, an optionally saturated C3-9 cycloalkyl group, a C5-10 aryl group, the groups being optionally substituted by a halogen, a hydroxy, a C1-5 alkoxy, an amino, a sulfino, a sulonfyl, with R4 representing an alkyl, an alkoxy or an alkylcarbonyl, the alkyl, cycloalkyl, aryl groups optionally including one or more heteroatoms, or R and R1 together represent an optionally saturated C2-6 substituted alkyl group, an optionally saturated C3-9 cycloalkyl group, a C5-10 aryl group, the cycloalkyl or aryl groups being optionally substituted by a C1-5 alkyl, a halogen, a hydroxy, a C1-5 alkoxy, an amino, a sulfino, a sulonfyl, with R4 representing an alkyl, an alkoxy or an alkylcarbonyl, the alkyl, cycloalkyl, aryl groups optionally including one or more heteroatoms, R2 and R3, which can be identical or different, represent an optionally saturated C3-
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: September 21, 2004
    Assignee: PPG-SIPSY
    Inventors: Michel Bulliard, Blandine Laboue, Sonia Roussiasse