Abstract: The present invention is directed to a compound of formula I, and processes for the manufacture of said compounds as well as medicaments containing said compound. The compounds according to this invention show anti-proliferative and differentiation-inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.

Abstract: Disclosed are modified inorganic particles and methods of preparing the same. The modified inorganic particle comprises an inorganic particle with hydroxyl groups, and a surface modifier coupled to the inorganic particle via a urethane linkage, wherein the surface modifier has an ethylenically unsaturated end group. The method comprises providing an inorganic particle with hydroxyl groups; providing a surface modifier with an isocyanate group at one end and an ethylenically unsaturated group at the other end; and mixing the inorganic particle with the surface modifier for reaction such that the surface modifier is coupled to the inorganic particle.

Abstract: A composition includes a metal precursor. The metal precursor may include an inorganic ligand and a metal cation. The inorganic ligand may include a carbamate group. An associated method is provided.

Abstract: Surface-modified, structurally modified fumed silicas Surface-modified, structurally modified fumed silicas are surface-modified with N-containing silicon compounds. They are used as fillers in resins and adhesives.

Abstract: The present invention relates to a macromonomer having a polydimethylsiloxane backbone that has a mol % dimethyl siloxanes, b mol % siloxanes substituted with -K-RIM, c mol % siloxanes substituted with -K-RIM-Z and d mol % siloxanes substituted with -L-Z, and in which the terminal siloxane groups are tri-substituted with R, wherein RIM is a refractive index modifying group; Z is a free radically polymerisable group; K is a spacer group; L is optional and is a spacer group; each R is independently selected from an RIM, a lower alkyl group, hydrogen or Z; and a is a molar percentage of the macromonomer which is in the range of from 0 to 95 mol %; b is a molar percentage of the macromonomer which is in the range of from 5 to 99 mol %; c is a molar percentage of the macromonomer which is in the range of from 0 to 2 mol %; and d is a molar percentage of the macromonomer which is in the range of from 0 to 2 mol %; with the proviso that c and d are not both 0 mol %.

Abstract: Provided is a photosensitive silane coupling agent for forming a low-defect microparticle pattern, dot array pattern, or hole array pattern with a smaller number of process steps, and a method of forming a pattern using such photosensitive silane coupling agent. Used is a photosensitive silane coupling agent having a secondary amino group protected by an o-nitrobenzyloxycarbonyl group.

Abstract: Disclosed are modified inorganic particles and methods of preparing the same. The modified inorganic particle comprises an inorganic particle with hydroxyl groups, and a surface modifier coupled to the inorganic particle via a urethane linkage, wherein the surface modifier has an ethylenically unsaturated end group. The method comprises providing an inorganic particle with hydroxyl groups; providing a surface modifier with an isocyanate group at one end and an ethylenically unsaturated group at the other end; and mixing the inorganic particle with the surface modifier for reaction such that the surface modifier is coupled to the inorganic particle.

Abstract: A process is provided for making a moisture-curable silylated resin composition by reacting (i) at least one polyol, (ii) at least one polyisocyanate and (iii) at least one isocyanatosilane, optionally in the presence of catalyst, wherein the NCO/OH ratio is less than 1. The resulting moisture-curable silylated resin composition is useful in the manufacturer of each product as moisture-curable sealants, coatings and adhesives.

Abstract: The present invention includes insecticidal carbamates that are useful, for example, for the control of insects, such as mosquitoes, which can be used in applications where exposure to and/or contact with humans is likely. The insecticides of the present invention include phenyl N-methyl carbamates and compositions comprising them that exhibit species-selective inhibition of acetylcholinesterase (AChE) and are preferably toxic to mosquitoes but not humans. Of particular interest are compounds of Formula (I) and Formula (II): Compounds of Formula (I) and Formula (II) are especially suitable for insecticide treated nets and indoor residual spraying for mosquito control.

Abstract: Coating compositions repairable by introduction of energy and comprising defined siloxanes, coatings obtained therewith and repairable by introduction of energy, methods of producing them, and their use.

Abstract: There is provided a hydroxyl-functional carbamoyl organosilicon compound, an anti-corrosion and/or adhesion promoting coating composition based thereon, a method for coating a metal surface employing the coating composition and the resulting coated metal article.

Abstract: The invention generally relates to methods of forming vinyl(thio)carbamates and more particularly to a vinylchloroformate-free method of synthesizing (N-vinyloxycarbonyl)-3-aminopropyltris(trimethylsiloxysilane).

Abstract: Blocked silyl isocyanates contain a methylene group between the blocked isocyanate group and silicon. The blocked isocyanates are easily prepared in high yield and purity.

Abstract: The present invention relates to an acrylic pressure sensitive adhesive composition containing organic functional groups of urethane and pyridine, more precisely an acrylic pressure sensitive adhesive composition which has excellent removability owing to its low initial peel strength on glass and excellent long-term durability since the peel strength of the pressure sensitive adhesive composition onto glass is being increased under high temperature and high humidity. The present invention also relates to an acrylic pressure sensitive adhesive composition for a polarizer having excellent adhesive functions and durability, a polarizer and a LCD containing the same.

Abstract: The present invention provides a silane molecule which combines pre-activated and protein-resistant functionalities in one molecule; the molecule has a general formula: A-(CH2)n—(O[CH2]t)m—(CH2)v—Y ??(1) wherein A is a functional group for binding to a substrate and Y is a functional group for binding to biomolecules. The invention furthermore provides a method for the synthesis of such a silane molecule and a method for depositing a monolayer of such silane molecules onto a substrate. Such a monolayer of silane molecules may be used in biosensors, DNA/protein micro-arrays or other sensor applications. For further lowering the protein binding to the surface of the biosensor, the monolayer may furthermore comprise second silane molecules with formula: B—(CH2)o—(OCH2CH2)r—Z.

Abstract: A process for the preparation of organoalkoxysilanes containing one or more organic functional groups derived from organic acids or hydrogen cyanates, by a continuous or batch process utilizing a solid guanidinium salt as a phase transfer catalyst for the reaction between a liquid phase haloalkylalkoxysilane and a solid phase alkali or alkaline earth metal salt or ammonium salt of an organic acid or a metal cyanate.

Abstract: Including a triazine UV light absorber having a silane group in a coating improves scratch and mar resistance after weathering.

Abstract: The present invention relates, in general, to tintable abrasion resistant coating compositions utilizing a tint additive and methods of making and using same. More particularly, but not by way of limitation, the tint additive is a polyethylene oxide polymer that is end capped on at least one “R” group with a silica containing compound.

Abstract: The invention relates to amido-functional aminopolydiorganosiloxanes, a method for the preparation thereof, formulations containing such amido-functional aminopolydiorganosiloxanes, and the use thereof.

Abstract: Provided are compounds having molecular components capable of transporting/injecting hole and an organic EL device having a self-assembled monolayer comprising the same. The compound has the following formula: Ar—R—SiX3 wherein Ar is a functional group having hole transporting or injecting capability, R is a C1 to C22 alkyl group, and X is an alkoxy group or halogen.

Abstract: Disclosed is an oxazolidine compound represented by the following formula (1). [R1 represents a hydrocarbon group having 1 to 6 carbon atoms; R2 and R3 independently represent a hydrogen atom or a monovalent hydrocarbon group having 1 to 15 carbon atoms, or R2 and R3 combine to form an alicyclic ring or an aromatic ring; R4 and R5 independently represent a methyl group or an ethyl group; R6 represents a single bond or —(R7—NHCOO—R8—OCONH)p—, R7 and R8 independently represent a divalent organic group, and p represents an integer of 1 to 15; m represents 2 or 3; n represents an integer of 1 to 3]. A curable resin composition using the oxazolidine compound as a latent curing agent have excellent curability and excellent storage stability, in particular, excellent storage stability in a state where the resin composition contains only the curable ingredient(s) and the latent curing agent.

Abstract: Disclosed is a polyether polyurethane comprising (A) at least one polyisocyanate having two or more isocyanate groups, which is selected from the group consisting of an aromatic polyisocyanate and an aliphatic polyisocyanate; (B) a polyoxytetramethylene glycol (PTMG) having a number average molecular weight of from 500 to 4,000, a molecular weight distribution (Mw/Mn) of 1.75 or less, and a content of high molecular weight PTMG molecules of 10% by weight or less; and (C) at least one chain extender selected from the group consisting of a C2-C10 polyol having two or more hydroxyl groups and a C2-C10 polyamine having two or more amino groups. Also disclosed is a urethane prepolymer which comprises the above-mentioned components (A) and (B) and which has terminal isocyanate groups.

Abstract: A monomer as represented by general formula (a) or (a′) below, with which a polymer having high oxygen permeability and transparency and suited to an ophthalmic lens is obtained, is provided.

Abstract: This invention pertains to novel methods for the synthesis of certain nitrogen mustard prodrugs, such as N-[4-[N,N-bis(2-haloethylamino)-phenoxycarbonyl]-L-glutamic acid: wherein: X2 is a halo group, and is —F, —Cl, —Br, or —I; n is an integer from 0 to 4; and, each RA is an aryl substituent. The methods comprise, at least, the steps of: glutamate conjugation (GC); silyloxy deprotection (SD); and, sulfonic esterification (SU). Certain preferred methods comprise the steps of: amine substitution (AS); silyloxy protection (SP); phenolic deprotection (PD); activation (AC); glutamate conjugation (GC); silyloxy deprotection (SD); sulfonic esterification (SU); halogenation (HL); glutamate deprotection (GD); and glutamic acid protection (GP).

Abstract: A process is provided for preparing an N-silylorganocarbamate, which comprises: providing a mixture of aminoorganosilane and a catalytically effective amount of basic catalyst and; combining the mixture of aminoorganosilane and basic catalyst with an organocarbonate ester the mixture of aminoorganosilane and basic catalyst, the organocarbonate ester or both being at elevated temperature at the time of their being combined.

Abstract: This invention relates to chemical compositions comprising one or more urethane oligomers of at least two repeating units selected from the group consisting of fluorine-containing urethane oligomers and long-chain hydrocarbon-containing urethane oligomers. These urethane oligomers comprise the reaction product of (a) one or, more polyfunctional isocyanate compounds; (b) one or more polyols; (c) one or more monoalcohols selected from the group consisting of fluorochemical monoalcohols, optionally substituted long-chain hydrocarbon monoalcohols, and mixtures thereof; (d) one or more silanes; and optionally (e) one or more water-solubilizing compounds comprising one or more water-solubilizing groups and at least one isocyanate-reactive hydrogen containing group. The chemical compositions of the present invention can be applied as coatings and these coatings can impart stain-release characteristics and resist being worn-off due to wear and abrasion.

Abstract: Improved synthesis of seco(−)CBI (5-hydroxy-3-amino-1-[S]-(chloromethyl)-1,2-dihydro-3H-benz(e)indole): and improved syntheses therefrom of a wide variety of CC-1065 analogs that comprise a cyclopropabenzidole (CBI) alkylating moiety, and which are collectively DC1 and its derivatives, for the synthesis of cell-targeted therapeutic agents.

Abstract: A charge transport composition containing aromatic amines with crosslinkable silanes as represented by the formula 1

Abstract: Powder coating or adhesive formulations include as a component thereof a silane of formula (I) or hydrolyzates or condensates thereof where R1 is a hydrocarbon, acyl, alkylsilyl, or alkoxysilyl group, R2 is a monovalent hydrocarbon group; R3 is alkylene, optionally interrupted with one or more ether oxygen atoms; a is 0 or 1; Z is a direct bond or a divalent linking group; X is an m-valent organic group or H; and m is 1-20. The silanes are useful as crosslinkers, property modifiers and/or adhesion promoters. Powder adhesives may be similarly formed with the silanes of formula (I). Fillers or pigments, such as titanium dioxide fillers, which are treated with silanes, especially silanes having alkyl, epoxy, acryl, methacryl, polyether, amino, acid anhydride, hydroxyalkyl, carbamato or ureido functionality, may also be usefully employed in powder coating formulations.

Abstract: A novel perfluoropolyether-modified aminosilane cures into a film having improved water and oil repellency and anti-staining properties. A surface treating agent comprising the aminosilane, and an article with a coating of the aminosilane are also provided.

Abstract: The present invention discloses hydrogen bond stabilized surface modifying agents having a fluorinated or semi-fluorinated carbon-containing tail group, an internal moiety capable of intermolecular hydrogen bonding or related acid-base interactions and a head group capable of reacting or interacting with surfaces such as metal, non-metallic, ceramic, other inorganic oxide or organic surfaces. The present invention also discloses cost effective method for making the agents, methods for treating surfaces therewith, the treated surfaces and devices made therefrom.

Abstract: Silanes of the general formula are prepared, wherein R1, R2 and R3 in the molecule are the same or different and represent aliphatic or aromatic hydrocarbon groups, R4 is a divalent hydrocarbon group with 4 to 12 carbon atoms and a lateral hydroxyl group, wherein the hydrocarbon group can be interrupted by an ether oxygen, R5 is a hydrophilic, ionic group. A method for synthesizing these compounds is described. The silanes greatly lower the surface tension of aqueous solutions, the surface tension being reduced to values of about 23 mN/m. The silanes are biologically degradable and have pronounced surfactant properties.

Abstract: There are disclosed novel quaternary ammonium functional silicones and silanes and methods to make quaternary ammonium functional silicones and silanes. Quaternary ammonium functionality may be provided through the use of cationizing agents.

Abstract: An adhesion promoter containing silane, and carbamate, thiocarbamate or urea functionality, and electron donor or electron acceptor functionality, displays low volatility.

Abstract: Processes for preparing carbamatoorganosilanes from aminoorganosilanes, ureas and alcohols. These compounds are useful for surface modification of inorganic and organic materials, as adhesion promoters between inorganic materials and organic polymers, as crosslinking agents for the moisture-curing of polymers, for PU sealants, in the coating and adhesive sector, and for the production of biologically active products, such as insecticides and herbicides.

Abstract: The present invention relates to iodonium salts containing urethane groups of reduced crystallization tendency, to a process for their preparation, and to their use for the radiation curing of cationically curing compositions.

Abstract: Powder coating formulations include as a component thereof a silane formula I: where R1 is a hydrocarbon, acyl, alkylsilyl or alkoxysilyl group; R2 is a monovalent hydrocarbon group; R3 is alkylene, optionally interrupted with one or more ether oxygen atoms; a is 0 or 1; Z is a direct bond or a divalent organic linking group; X is an m-valent organic group or H; and m is 1-20. The silanes are useful as crosslinkers, property modifiers and/or adhesion promoters. Powder adhesives may be similarly formed with silanes of formula I.

Abstract: Processes for preparing carbamatoorganosilanes from aminoorganosilanes, ureas and alcohols. These compounds are useful for surface modification of inorganic and organic materials, as adhesion promoters between inorganic materials and organic polymers, as crosslinking agents for the moisture-curing of polymers, for PU sealants, in the coating and adhesive sector, and for the production of biologically active products, such as insecticides and herbicides.

Abstract: Powder coating formulations which include as a component thereof a silyl carbamate of the formula: where R1 is a hydrocarbon or acyl group; R2 is a monovalent hydrocarbon group; R3 is alkylene, optionally interrupted with one or more ether oxygen atoms; a is 0 or 1; X is an m-valent organic group; m is 1-6; and, either A=NH and B=O, or A=O and B=NH. The silanes are useful as crosslinkers and/or adhesion promoters.

Abstract: A phenylacetylene derivative represented by the formula [I]: {wherein X is a halogen atom, a C1-C6 alkyl group, a C2-C6 alkoxy group, a C2-C6 haloalkyl group, etc., n is 0 or an integer of from 1 to 4, R1 is a C1-C6 alkyl group, R2 is a hydrogen atom, a C1-C6 alkyl group, a C2-C6 alkynyl group, a C2-C6 alkynyl group, a C1-C6 alkoxy group, etc., A is a C1-C6 alkylene group which may be branched, G is an oxygen atom, a sulfur atom or a —NR3— group; R3 is a hydrogen atom or a C1-C6 alkyl group, and Y is a hydrogen atom, a C1-C10 alkyl group, said group may be substituted by a halogen atom, a hydroxyl group or a C1-C6 alkoxy group], a C2-C6 alkenyl group, etc.; and an agricultural/horticultural fungicide containing the same as the active ingredient.

Abstract: The present invention relates to polymerizable terminal group-containing polyorganosiloxane having a number average molecular weight of 500 to 100000 represented by the following Formula (1): wherein R1, R2, R3, R4 and R5 each represent a linear or branched alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 4 to 10 carbon atoms or an aryl-containing group having 6 to 10 carbon atoms; R6 represents a hydrogen atom, a linear or branched alkyl group having 1 to 5 carbon atoms or an aryl-containing group having 6 to 10 carbon atoms; n represents 1 or more and m represents 0 or more, in which n+m represents an average polymerization degree and is 4 to 1100; X represents an alkylene group having 2 to 20 carbon atoms; Y represents —OCH2CH2—, —OCH(CH3)CH2— or —OCH2CH(CH3)—; p represents 3 or more; and Z represents an alkylene group having 1 to 20 carbon atoms.

Abstract: The invention relates to a novel amino acid silicon polymer with good adhesion to the keratin layer of the skin, a method of preparing the amino acid silicon polymer, a cosmetic particles surface-treated with the amino acid silicon polymer, and a color cosmetic composition including the cosmetic particles. According to the present invention, the particles surface-treated up to 3% to the maximum with the amino acid silicon polymer prepared by reacting an amino acid and a functional silicon polymer in the manner of organic synthesis have water resistance and usability peculiar to silicon-treated pigments and take positive surface charges, thereby offering good adhesion to the skin and durability. Due to these characteristics, the cosmetic containing the surface-treated particles of the present invention is superior in the cosmetic effect to that containing the conventional surface-treated particles.

Abstract: A sprayable coating composition that contains at least one soluble film-forming silicon-containing compound having, on average, more than one fuctionalized silicon group, a volatile organic carrier, a polymer microparticle component, and a catalyst; a substrate coated with the composition; a process for coating the substrate to provide a protective finish; the finish-protected substrate; certain oligomeric compounds and a process therefor.

Abstract: Intermediates having the formula wherein BI is —CH2OH or —CH2ORP, and RP is an alcohol protecting group; a is 1, 2, or 3; TI is —OH or QI is phenyl, naphthyl ohr heteroaryl having 1-3 substituents; Ra and Rc are the same, and are H, or are selected from alkyl, cycloalkyl and aryl groups, the groups being optionally substituted with one or more substituents selected from alkyl cycloalkyl, aryl, or —OH; or Ra and Rc together with the C—N—C chain to which they are bound, form a 5-7 membered ring; Rb and Rd are the same, and are H, or are selected from alkyl, cycloalkyl and aryl groups, the groups being optionally substituted with one or more substituents selected from alkyl, cycloalkyl, aryl, or —OH; and D is a directing group capable of directing lithiation alpha to a nitrogen atom of a nitrogen compound having D as a substituent bound to the nitrogen atom when the nitrogen compound is reacted with s-butyl lithium, are disclosed

Abstract: Silanes of the general formula are prepared, wherein R1, R2 and R3 in the molecule are the same or different and represent aliphatic or aromatic hydrocarbon groups, R4 is a divalent hydrocarbon group with 4 to 12 carbon atoms and a lateral hydroxyl group, wherein the hydrocarbon group can be interrupted by an ether oxygen, R5 is a hydrophilic, ionic group. A method for synthesizing these compounds is described. The silanes greatly lower the surface tension or aqueous solutions, the surface tension being reduced to values of about 23 mN/m. The silanes are biologically degradable and have pronounced surfactant properties.

Abstract: The invention relates to varnished metal wires with one or more electrically insulating varnish coatings, at least one of the electrically insulating varnish coatings representing an organically modified silicic acid (hetero) polycondensate, which has been obtained by partial or total hydrolytic condensation of one or more hydrolytically condensable compounds of silicon and if necessary other elements from the group B, A1, P, Sn, Pb, the transition metals, the lanthanides and actinides, and/or from precondensates derived from the abovenamed compounds, if necessary in the presence of a catalyst and/or of a solvent by the action of water and moisture.

Abstract: Hydrolysable and polymerizable or polyadditive silanes and methods of their production and the production of (hetero)silicic acid polycondensates or of polymers.

Abstract: The use of linear or cyclic silicon compounds containing at least one chromophoric group of quinone or azo type as direct dyes in dye compositions intended for dyeing human keratin fibers and in particular the hair. The invention also relates to novel silicon compounds and dye compositions containing them, as well as to the corresponding direct dyeing process.

Abstract: Novel monomers of the general formula ##STR1## where b is 0 or 1, a is 1, 2, 3 or 4, R.sup.2 is a monovalent alkyl radical and R is an organic radical. The novel monomers may be employed to produce novel copolymers useful as hydrogel, soft non-hydrogel and/or rigid gas permeable contact lens materials.

Abstract: The invention describes novel organosilicon compounds having fluorescent groups, containing units of the formula ##EQU1## where R is an identical or different, a monovalent, optionally substituted hydrocarbon radical having from 1 to 18 carbon atom(s) per radical, which may be interrupted by one or more oxygen atom(s),X is identical or different, and is a chlorine atom or a radical of the formula OR.sup.1,whereR.sup.1 is a hydrogen atom, or an alkyl radical having from 1 to 8 carbon atom(s) per radical which may be substituted by an ether oxygen atom,E is an organic radical having one or more (meth)acrylate groups,A is a radical of the formula--R.sup.2 [--NR.sup.3 --L].sub.x or --R.sup.2 [--S--L].sub.x(II),whereR.sup.2 is a divalent or trivalent, optionally substituted hydrocarbon radical having from 2 to 50 carbon atoms per radical, which is substituted by one or more groups of the formulae ##STR1## x is 1 or 2, R.sup.3 is as defined for R.sup.1 or is a radical of the formula --C(.dbd.O)--R.sup.