Plural -c(=o)s- Groups Containing Patents (Class 558/251)
  • Patent number: 10857073
    Abstract: Radically polymerizable, difunctional phenylene sulfide according to Formula I in which X, Y independently of each other in each case are absent or are O or NR6, R1, R2 independently of each other in each case are H, a linear or branched C1 to C10 alkyl radical, —OR7, —SR8, Cl or Br, R3 is absent or is a C1-C10 alkylene radical which can be interrupted by O or S, R4 is absent or is a C1-C10 alkylene radical which can be interrupted by O or S, wherein R3 and R4 cannot be absent at the same time, R5 is H or a C1-C5 alkyl radical, R6, R7, R8 independently of each other in each case are H or a linear or branched C1 to C10 alkyl radical, a, b, c, d independently of each other in each case are 0 or 1 and e is 1 or 2.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: December 8, 2020
    Assignee: Ivoclar Vivadent AG
    Inventors: Norbert Moszner, Urs Karl Fischer, Pascal Fässler
  • Patent number: 9404009
    Abstract: The present invention relates to novel polymer dispersants and to a liquid compositions containing solid fine particles, such as organic or inorganic pigments and fillers, and the polymer dispersants.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: August 2, 2016
    Assignee: BASF SE
    Inventors: Huiguang Kou, Clemens Auschra, Frank Pirrung
  • Patent number: 9376603
    Abstract: According to the present invention, a polymerizable composition having excellent storage stability can be provided by adding an acid that serves as a stabilizing agent and a free-radical polymerization inhibitor to a polymerizable composition that contains a polythiol compound and an enic compound having a phenylthio backbone as monomer components. In the present invention, an embodiment in which the acid is at least one compound having a protonic-acid-type functional group which is selected from phosphoric acid, phosphonic acid, phosphinic acid, sulfonic acid, sulfoneimide and carboxylic acid is preferred.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: June 28, 2016
    Assignee: MITSUBISHI GAS CHEMICAL COMPANY, INC.
    Inventors: Hitoshi Okazaki, Kousuke Namiki, Motoharu Takeuchi
  • Publication number: 20140306157
    Abstract: Subject It is to provide a polymerizable compound having a high polymerization reactivity, a high conversion yield and a high solubility in a liquid crystal composition, a polymerizable composition including the compound, a liquid crystal composite prepared from the composition and a liquid crystal display device containing this composite. Means for Solving the Subject A compound represented by formula (1). In this formula, for example, P1 and P2 are —SCO—CH?CH2; Sp1 and Sp2 are a single bond; ring A1, ring A2, ring A3 and ring A4 are 1,4-phenylene; Z1, Z2 and Z3 are a single bond; and a is 1, and b and c is 0.
    Type: Application
    Filed: April 2, 2014
    Publication date: October 16, 2014
    Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATION
    Inventors: Yasuyuki GOTOH, Masakazu YANO
  • Publication number: 20140308304
    Abstract: The present invention relates to novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with oligonucleotides, to facilitate the cellular uptake and endosomal escape, and to knockdown target mRNA both in vitro and in vivo. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.
    Type: Application
    Filed: December 7, 2012
    Publication date: October 16, 2014
    Inventors: Muthiah Manoharan, Kallanthottathil G. Rajeev, Muthusamy Jayaraman, Akin Akinc, Shigeo Matsuda, Martin Maier
  • Publication number: 20130211055
    Abstract: Dithioamine reducing agents useful for the reduction of disulfide bonds. The reducing agents of this invention are useful, for example, to reduce disulfide bonds, particularly in proteins, or to prevent the formation of disulfide bonds, particularly in proteins and other biological molecules. Reducing agents of this invention are useful and suitable for application in a variety of biological applications, particularly as research and synthetic reagents. The invention provides S-acylated dithioamines which can be selectively activated reducing agents by removal of the S-acyl groups enzymatically or chemically. The invention further provides dithiane precursors of thioamino reducing agents. The invention provides dithioamine reducing agents, S-acylated dithioamines and dithianes which are immobilized on surfaces, including among others, glass, quartz, microparticles, nanoparticles and resins.
    Type: Application
    Filed: February 15, 2013
    Publication date: August 15, 2013
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: Wisconsin Alumni Research Foundation
  • Publication number: 20130177961
    Abstract: Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms polya and polyb, respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEGa and mPEGb have the structure CH3O—(CH2CH2O)nCH2CH2— where n may be the same or different for polya- and polyb- and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.
    Type: Application
    Filed: December 14, 2012
    Publication date: July 11, 2013
    Applicant: NEKTAR THERAPEUTICS
    Inventor: NEKTAR THERAPEUTICS
  • Patent number: 8133924
    Abstract: Demulsifiers containing an anionic surfactant selected from alkylsulfosuccinates, alkylsulfonates, alkylphosphonic acids, and their salts; a nonionic surfactant selected from ethylene oxide/propylene oxide copolymers, ethoxylated fatty acids of polyethylene glycol, terpene alkoxylates, and modified alkanolamides; or a combination of an anionic and a nonionic surfactant, and methods of use thereof in breaking emulsions.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: March 13, 2012
    Assignee: Rhodia Operations
    Inventors: Ruela Talingting-Pabalan, Manilal S. Dahanayake, Gary Woodward, Herve Adam
  • Patent number: 7667043
    Abstract: Aromatic and heteroaromatic molecular structures with controllable electron conducting properties are derived from the incorporation of electron active substituents in selective positions. Such compounds can form self-assembled layers on metal or other substrates, and can be used in molecular scaled opto-electronic devices including field-effect transistors, light-emitting diodes and photovoltaic cells.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: February 23, 2010
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Ross Getty, Simona Percec
  • Patent number: 7659416
    Abstract: Enediyne compounds of the formula: (1) characterized in that the structure thereof is very simple and the production process is easy, and that the molecular length thereof is shorter than those of compounds having been proposed. Consequently, electrode assemblies comprising any of these enediyne compounds are highly promising in the application to nanomolecular wiring (nanomolecular wire) whose production has been difficult.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: February 9, 2010
    Assignees: Tokyo Institute of Technology, Nissan Chemical Industries, Ltd.
    Inventors: Masamichi Fujihira, Fumie Sato, Yuuki Takayama, Go Ono
  • Publication number: 20090209664
    Abstract: Demulsifiers containing an anionic surfactant selected from alkylsulfosuccinates, alkylsulfonates, alkylphosphonic acids, and their salts; a nonionic surfactant selected from ethylene oxide/propylene oxide copolymers, ethoxylated fatty acids of polyethylene glycol, terpene alkoxylates, and modified alkanolamides; or a combination of an anionic and a nonionic surfactant, and methods of use thereof in breaking emulsions.
    Type: Application
    Filed: April 2, 2009
    Publication date: August 20, 2009
    Applicant: Rhodia Inc.
    Inventors: Ruela Talingting-Pabalan, Manilal S. Dahanayake, Gary Woodward, Herve Adam
  • Publication number: 20090036698
    Abstract: Enediyne compounds of the formula: (1) characterized in that the structure thereof is very simple and the production process is easy, and that the molecular length thereof is shorter than those of compounds having been proposed. Consequently, electrode assemblies comprising any of these enediyne compounds are highly promising in the application to nanomolecular wiring (nanomolecular wire) whose production has been difficult.
    Type: Application
    Filed: March 17, 2006
    Publication date: February 5, 2009
    Inventors: Masamichi Fujihira, Fumie Sato, Yuuki Takayama, Go Ono
  • Patent number: 7078551
    Abstract: A blocked mercaptosilane of the structure: G-C(?O)—S—CH2CH2CH2SiX3 is disclosed wherein each X is an independently selected RO— group or R— group wherein each R is independently selected from the group consisting of hydrogen, alkyl that may or may not contain unsaturation, alkenyl groups, aryl groups, and aralkyl groups, such moieties other than hydrogen having from 1 to 18 carbon atoms, at least one X is RO—, and G is a monovalent alkyl group.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: July 18, 2006
    Assignee: General Electric Company
    Inventors: Richard W. Cruse, Robert J. Pickwell, Eric Raymond Pohl, Keith J. Weller
  • Patent number: 6972343
    Abstract: The invention concerns drug precursors with antimalarial effect, characterised in that it consists in quaternary bis-ammonium salts of general formula (I) wherein A and A?, identical or different, are respectively either a group A1 and A?1 of formula (1) wherein n=2 to 4; R?1 is hydrogen, C1-C5 alkyl, optionally substituted by an aryl, a hydroxy, an alkoxy, wherein the alkyl comprises 1 to 5 C, or aryloxy and W is halogen or a nucleofuge group; or a group A2 which represents formyl-CHO, or acetyl-COCH3.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: December 6, 2005
    Assignee: CNRS
    Inventors: Henri Vial, Marie-Laure Ancelin, Valerie Vidal, Michele Calas, Jean-Jacques Bourguignon, Eric Rubi
  • Patent number: 6841653
    Abstract: A thiol carboxylate ester as shown by general formula (I) below, which has a half ester content of 0.0001 to 2 mass %, and favorably, which has a halogen content of not more than 2 mass % and/or to which a polymerization inhibitor such as a catechol family member is added.
    Type: Grant
    Filed: March 9, 2003
    Date of Patent: January 11, 2005
    Assignee: Nippon Shokubai Co., Ltd.
    Inventors: Yoshiyuki Takahashi, Yoichi Hino, Tatsuhito Matsuda
  • Patent number: 6753449
    Abstract: Cleavable alkene-containing linkers and supports useful for the solid phase synthesis of chemical compounds, and combinatorial libraries of compounds, are disclosed. Also disclosed are methods of making and using the linkers and supports.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: June 22, 2004
    Assignee: ArQule, Inc.
    Inventor: MaoJun Guo
  • Patent number: 6667341
    Abstract: Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having an oxygen, sulfur or nitrogen attached to a methylene group, to which is further attached a sulfur, nitrogen or CH2 group. Methods of treating illnesses and conditions, such as cancer, hemological disorders, inherited metabolic disorders and others, using these compounds are also disclosed.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: December 23, 2003
    Assignee: Beacon Laboratories, Inc.
    Inventors: Hsuan-Yin Lan-Hargest, Norbert L. Wiech
  • Publication number: 20030187288
    Abstract: A thiol carboxylate ester as shown by general formula (I) below, which has a half ester content of 0.0001 to 2 mass %, and favorably, which has a halogen content of not more than 2 mass % and/or to which a polymerization inhibitor such as a catechol family member is added.
    Type: Application
    Filed: March 9, 2003
    Publication date: October 2, 2003
    Applicant: Nippon Shokubai Co., Ltd.
    Inventors: Yoshiyuki Takahashi, Yoichi Hino, Tatsuhito Matsuda
  • Publication number: 20030171409
    Abstract: Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two carbonyl groups connected by a linking moiety having an oxygen, sulfur or nitrogen attached to a methylene group, to which is further attached a sulfur, nitrogen or CH2 group. Methods of treating illnesses and conditions, such as cancer, hemological disorders, inherited metabolic disorders and others, using these compounds are also disclosed.
    Type: Application
    Filed: October 29, 2002
    Publication date: September 11, 2003
    Applicant: Beacon Laboratories, Inc, a Delaware corporation
    Inventors: Hsuan-Yin Lan-Hargest, Norbert L. Wiech
  • Patent number: 6608125
    Abstract: A blocked mercaptosilane of the structure: G—C(═O)—S—CH2CH2CH2SiX3 is disclosed wherein each X is an independently selected RO— group wherein each R is independently selected from the group consisting of hydrogen, alkyl that may or may not contain unsaturation, alkenyl groups, aryl groups, and aralkyl groups, such moieties other than hydrogen having from 1 to 18 carbon atoms, and G is a monovalent alkyl of from 2 to 12 carbon atoms.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: August 19, 2003
    Assignee: Crompton Corporation
    Inventors: Richard W. Cruse, Robert J. Pickwell, Keith J. Weller, Eric R. Pohl
  • Publication number: 20030125575
    Abstract: Process for the preparation of (R)-2-bromo-3-phenylpropionic acid starting from D-phenylalanine, sodium nitrite and HBr in an aqueous solution, the reaction being carried out in the presence of a bromide salt, at a temperature between −10 and 30° C.
    Type: Application
    Filed: November 14, 2002
    Publication date: July 3, 2003
    Inventors: Franciscus Alphons Marie Lommen, Helmut Koller, Herbert Scherubl
  • Patent number: 6552226
    Abstract: A novel tandem acyl-Claisen rearrangement reaction is provided. An allylic reactant such as an allylic amine or an allylic thioether, having at least two functional groups that enable the reactant to undergo at least two successive Claisen rearrangement reactions, is reacted with an acid chloride in the presence of a Lewis acid catalyst composition composed of a Lewis acid and a second catalyst component selected from the group consisting of tertiary amines and non-nitrogenous bases. The stereochemistry of the reaction product is readily controlled by the positioning and size of substituents on the allylic reactant. The reaction may be carried out on a solid support, i.e., on the surface of a substrate suitable for conducting solid phase chemical reactions.
    Type: Grant
    Filed: September 26, 2000
    Date of Patent: April 22, 2003
    Assignee: The Regents of the University of California
    Inventor: David W. C. MacMillan
  • Publication number: 20020188154
    Abstract: Compositions for lithographic or flexographic inks are disclosed comprising at least one compound of Formula 1: 1
    Type: Application
    Filed: May 25, 2001
    Publication date: December 12, 2002
    Inventors: JoAnn Arceneaux, Peter Weissman
  • Publication number: 20020156061
    Abstract: Selective MMP-13 inhibitors are isophthalic acid derivatives of the formula 1
    Type: Application
    Filed: February 13, 2002
    Publication date: October 24, 2002
    Inventors: Nicole Chantel Barvian, David Thomas Connor, Richard Dennis Dyer, Adam Richard Johnson, William Chester Patt
  • Patent number: 6284258
    Abstract: The present invention relates to compounds that are two-part molecules, and compositions containing such compounds, in which one part is designed to become covalently bonded to the skin (bonding agent) and the other part (a characteristic use agent) is designed to impart some characteristic use, such as emolliency, moisturizing effect, anti-acne, anti-wrinkle, anti-pain, antimicrobial, antifungal, antiviral, anti-irritation, skin tanning and skin lightening effects, extended protection of the skin (e.g., from ultraviolet light, by incorporation of a sunscreen component; from toxic and/or irritating substances; from insects and skin parasites, by incorporation of insecticides and/or insect repellants; from free radicals or other agents, as in aging, by incorporation of antioxidants), or dyeing of hair, skin nails, wool or fuir. The covalently bonded part may also be useful to impart skin strengthening effect (e.g., from shear forces) or as wound healing agents.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: September 4, 2001
    Assignee: Arizona Board of Regents
    Inventors: Seth D. Rose, Rosemarie F. Hartman, Carmen Chow, Cathryn M. Rose, K. Daniel Rose
  • Patent number: 6172140
    Abstract: A cross-linkable polymeric casting composition includes an effective amount of an acrylic or methacrylic di- or polythiol monomer of the formula (1) wherein p is an integer of 0 or 1, M or M′ are each spacer groups selected from one or more of the following formulae (i), (ii) wherein m is an integer of 0 or 1 and n is an integer of 0 to 3, with the proviso that m and n are not both equal to zero, R1R2, R3 and R4, which may be the same or different, are selected from hydrogen, alkyl or substituted alkyl of 1 to 10 carbon atoms, alkoxy or substituted alkoxy of 1 to 10 carbon atoms, or R1 or R2 is (iii) and optionally a polymerisable comonomer.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: January 9, 2001
    Assignee: Sola International Holdings LTD
    Inventors: Huan Kiak Toh, Fang Chen, Chong Meng Kok
  • Patent number: 6117902
    Abstract: The present invention provides 6,8-Dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical, wherein they correspond to the following formula (I): ##STR1## in which: R represents OR.sub.3 or ##STR2## R.sub.3 representing a hydrogen atom, a linear or branched alkyl radical, or a radical of the formula ##STR3## n being an integer from 1 to 10 and r' and r", which are identical or different, representing a hydrogen atom, a linear or branched alkyl radical or, taken together, form with the nitrogen atom, a nitrogen-containing heterocycle optionally substituted with an optionally substituted oxygen or nitrogen atom,R.sub.5 and R.sub.4, identical or different, represent a hydrogen atom or a linear or branched alkyl radical,R.sub.1 and R.sub.2, which are identical or different, represent a hydrogen atom, a radical --COCH.sub.3 or a radical of formula:--CO(CH.sub.2).sub.2 SCH.sub.3 (II)with the proviso that at least one of the radicals R.sub.1 or R.sub.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: September 12, 2000
    Assignee: Galderman Research & Development, S.N.C. Sophia Abtipolis
    Inventors: Gerard Anthony Quash, Jacques Gore, Guy Fournet
  • Patent number: 6114485
    Abstract: A sulfur-containing O-(meth)acrylate compound of the following formula (1) is useful as a starting material for a resin composition used in optical applications such as a lens; wherein R represents hydrogen atom or methyl group; l represents an integer from 1 to 3; B is ##STR1## when B is ##STR2## n is 2; m is 1 or 2; A is selected from the following groups: ##STR3## wherein m represents 1 or 2; each ring may be substituted by one or more alkyl, alkylthio or alkoxy groups having 1 or 2 carbon atoms; p and q are 0 or 1, while m is 1 when p is 1;when B is ##STR4## n is 1; m is 2 or 3; A is selected from the following groups:--(CH.sub.2).sub.r --S--(CH.sub.2).sub.r --,--(CH.sub.2).sub.r --S--S--(CH.sub.2).sub.r --,--(CH.sub.2).sub.r --S--(CH.sub.2).sub.s --S--(CH.sub.2).sub.r -- and ##STR5## wherein r and s are an integer from 1 to 3; when B is ##STR6## n is 1; m is 2; A is selected from the following groups:--(CH.sub.2).sub.r --S--(CH.sub.2).sub.r --,--(CH.sub.2).sub.r --S--S--(CH.sub.2).sub.r -- and--(CH.sub.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: September 5, 2000
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Seiichi Kobayashi, Nobuya Kawauchi, Toshiyuki Suzuki, Masao Imai, Kenichi Fujii
  • Patent number: 5912366
    Abstract: .alpha.,.alpha.-Difluoro-.beta.-hydroxy thiol esters of Formula (III): ##STR1## wherein: R.sup.c and R.sup.d are independently selected from the group consisting of H, C.sub.1 -C.sub.6 alkyl, substituted C.sub.1 -C.sub.6 alkyl, S-tert-butyl difluorothioacet-2-yl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.8 cycloalkenyl, substituted C.sub.3 -C.sub.8 cycloalkyl, substituted C.sub.3 -C.sub.8 cycloalkenyl, aryl, substituted aryl, C.sub.6 -C.sub.10 fused aromatic rings, and substituted C.sub.6 -C.sub.10 fused aromatic rings; orR.sup.c and R.sup.d together make up a ring selected from the group consisting of C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.8 cycloalkenyl, substituted C.sub.3 -C.sub.8 cycloalkyl and substituted C.sub.3 -C.sub.8 cycloalkenyl;R.sup.e is selected from the group consisting of C.sub.1 -C.sub.10 alkyl, substituted C.sub.1 -C.sub.10 alkyl, aryl, substituted aryl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.8 cycloalkenyl, substituted C.sub.3 -C.sub.8 cycloalkyl and substituted C.sub.3 -C.sub.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: June 15, 1999
    Assignee: Eli Lilly and Company
    Inventor: John A. Weigel
  • Patent number: 5871721
    Abstract: S,S'-ethylidene dithioacetate is used as a flavoring ingredient for giving the edible products in which it is incorporated not only a sulphurous but also a green, fruity, rich and even meaty quality. It has been particularly successfully used in grapefruit and other fruit flavorings. It can also be used in the preparation of perfuming compostions.
    Type: Grant
    Filed: January 16, 1997
    Date of Patent: February 16, 1999
    Assignee: Firmenich SA
    Inventor: Regula Naef
  • Patent number: 5783735
    Abstract: A process for preparing polymeric amides is disclosed. The process comprises sequentially reacting a hydrocarbon polymer functionalized (e.g., via the Koch reaction) to contain acid, ester, thioacid and/or thioester groups with a heavy polyamine to form a partially derivatized product in which at least about 85% of the functional groups are converted to heavy (thio)amide groups, and then reacting the partially derivatized product with an excess of light amine to complete the derivatization by converting substantially all of the remaining functional groups to light (thio)amide groups. Products of the foregoing process are also disclosed, which products are useful as additives in fuels and in lubricants.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: July 21, 1998
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Jacob I. Emert, Joseph V. Cusumano, David C. Dankworth, William D. Diana, William B. Eckstrom, Keith R. Gorda, Antonio Gutierrez, Jon E. Stanat, Warren A. Thaler, Stephen Zushma
  • Patent number: 5756775
    Abstract: A process to make .alpha.,.alpha.-difluoro-.beta.-hydroxy thiol esters of formula (IIIA) ##STR1## comprising reacting a difluoroethanethioate of formula (IVA) ##STR2## with a second reactant selected from the group consisting of aldehydes, ketones, acid halides and esters; in a solvent and in the presence of a strong base; with the proviso that the process is conducted in the absence of a catalyst and in the absence of a silyl containing compound. These thiol esters are useful as intermediates in organic syntheses of pharmaceutical products.
    Type: Grant
    Filed: December 9, 1996
    Date of Patent: May 26, 1998
    Assignee: Eli Lilly and Company
    Inventor: John A. Weigel
  • Patent number: 5736747
    Abstract: Organic compounds having at least one ethylenically-unsaturated group are described, the organic compounds being suitable for use in coatable compositions as reactive diluents; compounds of the invention preferably have a divalent organic linking moiety devoid of reactive groups other than optional ethylenically-unsaturated groups, and a polar organic moiety and are particularly adept in solubilizing aminoplast resins having radiation-curable pendant groups.
    Type: Grant
    Filed: February 23, 1996
    Date of Patent: April 7, 1998
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Ernest L. Thurber, Eric G. Larson, Alan R. Kirk, Gregg D. Dahlke
  • Patent number: 5698722
    Abstract: A Koch functionalized product which is the reaction product of at least one polymer having a number average molecular weight of at least 500 and at least ethylenic double bond per polymer chain, with carbon monoxide and a nucleophilic trapping agent. The invention includes functionalized polymer, derivatives thereof and methods of making the same.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 16, 1997
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Joseph Victor Cusumano, William Daniel Diana, Jacob Emert, Keith Raymond Gorda, Richard H. Schlosberg, David A. Young, William Bernard Eckstrom, Edris Eileen Manry, Michael John Keenan
  • Patent number: 5629434
    Abstract: A Koch functionalized product which is the reaction product of at least one polymer having a number average molecular weight of at least 500 and at least one ethylenic double bond per polymer chain, with carbon monoxide and a nucleophilic trapping agent. The invention includes functionalized polymer, derivatives thereof and methods of making the same.
    Type: Grant
    Filed: September 25, 1995
    Date of Patent: May 13, 1997
    Assignee: Exxon Chemical Patents Inc
    Inventors: Joseph V. Cusumano, William D. Diana, Jacob Emert, Keith R. Gorda, Richard H. Schlosberg, David A. Young, William B. Eckstrom, Edris E. Manry, Michael J. Kennan
  • Patent number: 5523152
    Abstract: Organic compounds having at least one ethylenically-unsaturated group are described, the organic compounds being suitable for use in coatable compositions as reactive diluents; compounds of the invention preferably have a divalent organic linking moiety devoid of reactive groups other than optional ethylenically-unsaturated groups, and a polar organic moiety and are particularly adept in solubilizing aminoplast resins having radiation-curable pendant groups.
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: June 4, 1996
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Ernest L. Thurber, Eric G. Larson, Alan R. Kirk, Gregg D. Dahlke
  • Patent number: 5488128
    Abstract: The invention relates to a thio(meth)acrylic acid bisester of formula I ##STR1## where R.sub.1 represents hydrogen or methyl;r represents the number 0 or 1; ands, m, and n independently represent an integer from 2 to 6, with the proviso thatwhen r=0, s+n>4; andwhen r=1, s+m+n>6 useful as or monomer for high refractive index plastics.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: January 30, 1996
    Assignee: Roehm GmbH Chemische Fabrik
    Inventors: Martina Bader, Volker Kerscher
  • Patent number: 5436352
    Abstract: The present invention provides metal chelating compounds, to chelates and chelate-targeting agent conjugates formed from the chelating compounds, and to methods for making and using these compositions. The chelating compounds incorporate two nitrogen atoms and three sulfur atoms ("N.sub.2 S.sub.3 "), two nitrogen atoms and four sulfur atoms ("N.sub.2 S.sub.4 "), or three nitrogen atoms and three sulfur atoms ("N.sub.3 S.sub.3 "). Metals, and metal oxides, capable of being chelated by the compounds include those that are radionuclides, such as .sup.99m Tc and .sup.186/188 Re.The targeting agent portion of the chelate-targeting agent conjugates provided includes antibodies, peptides, hormones, enzymes and biological response modifiers. Methods for making the conjugates are provided and encompass the addition of a metal, or metal oxide, to a chelating compound prior to attachment to a targeting agent as well as subsequent to the attachment.
    Type: Grant
    Filed: December 6, 1991
    Date of Patent: July 25, 1995
    Assignee: NeoRx Corporation
    Inventors: Ananthachari Srinivasan, Alan R. Fritzberg, David S. Jones
  • Patent number: 5424472
    Abstract: The invention relates to a method of producing (meth)acryloylthio esters of general formula I ##STR1## where R represents hydrogen or methyl, and R.sup.1 represents a phenyl group, a substituted phenyl group, a C.sub.1-24 alkyl group, a substituted C.sub.1-24 alkyl group, a cyclic C.sub.3-24 alkyl group;comprising reacting (meth)acrylic acid anhydride (formula II) ##STR2## where R represents hydrogen or methyl, with at least the stoichiometric amount with a thiol or thiolate of formula IIIR.sub.1 --S--M, (III)where M represents hydrogen or a metal cation, andR.sub.1 is defined as above.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: June 13, 1995
    Assignee: Roehm GmbH Chemische Fabrik Patentabteilung
    Inventors: Martina Bader, Patrik Hartmann, Gerhard Schwinn
  • Patent number: 5399735
    Abstract: A thiol methacrylate or acrylate compound represented by the formula (1) or (2): ##STR1## wherein R.sup.1 is H or CH.sub.3 and X is selected from: ##STR2## wherein R.sup.1 is H or CH.sub.3 and m is an integer of 1 to 4. The thiol methacrylate or acrylate compound gives a resin having a high refractive index, a large Abbe number, and a good hardness and heat resistance, and giving little or no smell at processing.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: March 21, 1995
    Assignee: Toray Industries, Inc.
    Inventors: Yuichiro Iguchi, Michio Kimura, Koichiro Oka
  • Patent number: 5356925
    Abstract: Novel N-(mercaptoalkyl)urea or carbamates of the formulae I and II ##STR1## wherein A is a monocyclic or bicyclic arylene or heteroarylene;Q is hydrogen or R.sub.9 CO--;Y is --O--,--S-- or --NR.sub.8 --;R.sub.1 is lower alkyl, cyclolower alkyl, aryl or heteroaryl;R.sub.2 and R.sub.8 are independently hydrogen; lower alkyl; cyclolower alkyl; substituted lower alkyl; aryl; or heteroaryl;R.sup.3 is --OR.sub.5 or --NR.sub.5 R.sub.6 ;R.sub.4 is --(CH.sub.2).sub.q R.sub.7 ; or R.sub.2 and R.sub.4 and the carbons to which they are attached complete a ring;R.sub.5 and R.sub.6 are hydrogen, lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl or aryl lower alkyl, or R.sub.5 and R.sub.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: October 18, 1994
    Assignee: Schering Corporation
    Inventors: Bernard R. Neustadt, Alan Bronnenkant
  • Patent number: 5340487
    Abstract: The present invention is directed to an oil-soluble lubricating oil additive comprising at least one adduct of (A) a polyolefin of 700 to 5,000 number average molecular weight substituted with carboxylic acid producing moieties (preferably acid or anhydride moieties), and (B) a monoepoxy thiol.
    Type: Grant
    Filed: August 19, 1993
    Date of Patent: August 23, 1994
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Jacob Emert, Robert D. Lundberg
  • Patent number: 5273668
    Abstract: The present invention is directed to an oil-soluble lubricating oil additive comprising at least one adduct of (A) a polyolefin of 700 to 5,000 number average molecular weight substituted nitrogen- or ester-containing ashless dispersant and (B) a bis-keto/thioketo compound.
    Type: Grant
    Filed: January 25, 1993
    Date of Patent: December 28, 1993
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Jacob Emert, Antonio Gutierrez, Robert D. Lundberg
  • Patent number: 5241099
    Abstract: Aminomethylene compounds of the formula ##STR1## can be prepared by reaction of C-H-acid compounds of the formula ##STR2## with salts of the formula ##STR3## in the presence of simple inorganic bases, where the radicals R.sup.1 to R.sup.4, R.sup.7, R.sup.8 and X.sup..crclbar. have the meanings given in the description.
    Type: Grant
    Filed: March 16, 1992
    Date of Patent: August 31, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinz-Ulrich Blank, Helmut Kraus
  • Patent number: 5214181
    Abstract: This invention relates to novel compounds of the formula [I], which are useful for treatment of various diseases such as immunodeficiency and autoimmune diseases caused by immune disorders, processes for preparing the compounds and compositions containing the compounds as active ingredients.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: May 25, 1993
    Assignee: Santen Pharmaceutical Co., Ltd.
    Inventors: Takakazu Morita, Shiro Mita, Yoichi Kawashima
  • Patent number: 5205947
    Abstract: The present invention is directed to an oil-soluble lubricating oil additive comprising at least one adduct of (A) a polyolefin of 700 to 5,000 number average molecular weight substituted with carboxylic acid producing moieties (preferably acid or anhydride moieties), and (B) a monoepoxy thiol.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: April 27, 1993
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Jacob Emert, Robert D. Lundberg
  • Patent number: 5200101
    Abstract: Arylamine/hindered phenol, acid anhydride and thioester-derived reaction products, have been found to be effective multifunctional antioxidant, antiwear and rust inhibiting additives for lubricants and fuels.
    Type: Grant
    Filed: June 24, 1991
    Date of Patent: April 6, 1993
    Assignee: Mobil Oil Corporation
    Inventors: Shin-Ying Hsu, Andrew G. Horodysky, Douglas E. Johnson, David A. Blain
  • Patent number: 5194650
    Abstract: An acylcyclohexadionethiocarboxylic S-ester of the formula ##STR1## where R.sup.1 and R.sup.2 are substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, benzyl or phenyl, and R.sup.2 is additionally hydrogen, are prepared by reacting an acylcyclohexadione II ##STR2## with hydroxylamine or hydroxylamine-O-sulfonic acid in an inert solvent at from 0.degree. to 150.degree. C., to give an acylcyclohexadione compound III ##STR3## and then reacting the compound III with a mercaptan IVR.sup.2 --SH IVin the presence of an anhydrous acid HX to give an acylcyclohexadionethiocarboximidic S-ester salt V ##STR4## where X is the anion of the acid, and hydrolyzing the compounds V to the acylcyclohexadionethiocarboxylic S-ester I.
    Type: Grant
    Filed: February 10, 1992
    Date of Patent: March 16, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Juergen Kast, Juergen Schubert, Reinhard Kaczmarek
  • Patent number: 5183917
    Abstract: 4,4'-Bis(methacryloylthio)diphenylsulfide having the formula (I): ##STR1## and a curable composition characterized by comprising: (A) 4,4'-bis(methacryloylthio)diphenylsulfide having the above formula (I):(B) (i) another vinyl monomer copolymerizable with 4,4'-bis(methacryloylthio)diphenylsulfide having the above formula (I), and (ii) a polythiol represented by the formula (II):R-(SH).sub.n (II)wherein R is a polyvalent organic group and n represents an integer of 2 or more, wherein the content of the component (B)(i), when the component (B)(i) is present, in the total amount of said components (A), (B)(i) and (B)(ii) is 10 to 90% by weight, and the functional group equivalent ratio of the mercapto groups of the component (B)(ii), when the component (B)(ii) is present, to the methacryloyl groups of the component (A) is from 0.02 to 1.
    Type: Grant
    Filed: June 20, 1990
    Date of Patent: February 2, 1993
    Assignee: Showa Denko K.K.
    Inventors: Satoshi Maruyama, Naoki Minorikawa, Tsutomu Arakawa, Haruo Yoshida, Hirotaka Tagoshi, Kazuto Abe
  • Patent number: 5177109
    Abstract: Compounds, compositions and methods are described for treating a CNS disorder such as a cognitive disorder, epilepsy, depression, Parkinson's disease, Alzheimer's disease, a neurodegenerative disease or neurotoxic injury. Compound of interest are 2-amino-4,5-methyleneadipic acid compounds and derivatives defined by the formula I: ##STR1## wherein R.sup.1 is selected from hydrido, alkyl, cycloalkyl, aralkyl, aryloxyalkyl, arylthioalkyl, ##STR2## with each of R.sup.2, R.sup.3, R.sup.4 and R.sup.5 being independently selected from hydrido, alkyl, cycloalkyl, aryl and aralkyl; wherein each of X and Y is independently selected from hydroxyl, alkoxy, alkylthio, amino and ##STR3## with each of R.sup.6 and R.sup.7 being independently selected from hydrido, alkyl, cycloalkyl, aryl and aralkyl; wherein any of R.sup.1 through R.sup.
    Type: Grant
    Filed: July 19, 1991
    Date of Patent: January 5, 1993
    Assignee: G. D. Searle & Co.
    Inventors: Roberto Pellicciari, Benedetto Natalini, Maura Marinozzi, Alexis A. Cordi, Joseph B. Monahan, Thomas H. Lanthorn