Cyano Single Bonded And Nitrogen Or Phosphorus Double Bonded To The Same Carbon Atom (e.g., Alpha-imino Nitriles, Etc.) Patents (Class 558/300)
  • Publication number: 20150044122
    Abstract: A device and a method are provided for reacting a starting material in at least two reactors connected to each other, including the reacting of the starting material in a first reactor to a first product, removing the first product from the first reactor using a jet pump, wherein a negative pressure zone of the jet pump is operationally connected to the first reactor, so that the first product of the first reactor moves through the negative pressure zone in a propulsion jet of a propulsion medium of the jet pump, conducting the propulsion medium having the first product into a second reactor, wherein the first product is allowed to react into a second product, separating the second product from the propulsion medium and discharging the separated second product.
    Type: Application
    Filed: March 19, 2013
    Publication date: February 12, 2015
    Inventors: Stefan Zikeli, Friedrich Ecker
  • Publication number: 20130040395
    Abstract: The present invention relates to the use of a halogenated cyanocinnamic acid derivative with the general formula: wherein R is selected independently among F, Cl and Br, n=3, 4 or 5 and R? is selected among COOH, CONH2, SO3H and COOR? with R?=C1-O5-Alkyl; and/or of 4-bromo-?-cyanocinnamic acid and/or of ?-cyano-2,4-dichlorocinnamic acid in a matrix for a MALDI mass spectrometry of an analyte.
    Type: Application
    Filed: March 2, 2011
    Publication date: February 14, 2013
    Applicant: JOHANN WOLFGANG GOETHE-UNIVERSITÄT
    Inventors: Thorsten Jaskolla, Michael Karas
  • Publication number: 20110112166
    Abstract: Compounds comprising formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein B, Y, and A are as described in claims 1-10. Methods, compositions, and medicaments related thereto are also disclosed, for treating baldness, glaucoma or inflammatory bowel diseases.
    Type: Application
    Filed: May 4, 2009
    Publication date: May 12, 2011
    Applicant: ALLERGAN, INC
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Patent number: 7393961
    Abstract: (Per)haloethers having formula: X-(Rf)L-O—CF2CF2—O—CX1X2—CFX3X4 , ??(I) process for obtaining them and hypofluorites usable in the synthesis of said (per)haloethers.
    Type: Grant
    Filed: March 8, 2005
    Date of Patent: July 1, 2008
    Assignee: Solvay Solexis S.p.A.
    Inventors: Giovanni Fontana, Walter Navarrini
  • Patent number: 7115755
    Abstract: The invention relates to new reactive mesogenic azulene derivatives, their use as semiconductors or charge transport materials, in optical, electro-optical or electronic devices like for example liquid crystal displays, optical films, organic field effect transistors (FET or OFET) for thin film transistor liquid crystal displays and integrated circuit devices such as RFID tags, electroluminescent devices in flat panel displays, and in photovoltaic and sensor devices, and to a field effect transistor, light emitting device or ID tag comprising the reactive mesogenic azulenes.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: October 3, 2006
    Assignee: Merck Patent GmbH
    Inventors: Louise Diane Farrand, Michael Findlater, Mark Giles, Martin Heeney, Steven Tierney, Marcus Thompson, Maxim Shkunov, David Sparrowe, Iain McCulloch
  • Patent number: 6150379
    Abstract: The present invention relates to novel biheterocyclic derivatives which are factor Xa inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: November 21, 2000
    Assignee: Axys Pharmaceuticals, Inc.
    Inventors: Paul R. Fatheree, Thomas E. Jenkins, Martin S. Linsell, Sean G. Trapp, Erik J. Verner, Wendy B. Young
  • Patent number: 5770757
    Abstract: A catalyst having the atomic ratios set forth in the empirical formula below:A.sub.a B.sub.b C.sub.c Ge.sub.d Bi.sub.e Mo.sub..sub.12 O.sub.xwhereA=two or more of alkali metals, In and TlB=one or more of Mg, Mn, Ni, Co, Ca, Fe, Ce, Sm, Cr, Sb, and W; preferably B equals the combination of Fe and at least one element selected from the group consisting of Ni and Co and at least one element selected from the group consisting of Mg, Mn, Ca, Ce, Sn, Cr, Sb, and WC=one or more of Pb, Eu, B, Sn, Te and Cua=0.05 to 5.0b=5 to 12c=0 to 5.0d=0.1 to 2.0e=0.1 to 2.0x=the number of oxygen atoms required to satisfy the valency requirements of the other elements andb>a+c.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: June 23, 1998
    Assignee: The Standard Oil Company
    Inventors: Tama Lee Drenski, Maria Strada Friedrich, Christos Paparizos, Michael J. Seely, Dev Dhanaraj Suresh
  • Patent number: 5468870
    Abstract: Dye-donor element for use according to thermal dye sublimation transfer comprising a support having thereon a dye layer containing a dye corresponding to the following formula ##STR1## wherein Z represents CN, COOR.sup.1 or CONR.sup.2 R.sup.3 ;R.sup.1, R.sup.2 and R.sup.3 each independently represent hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, or R.sup.2 and R.sup.3 together represent the necessary atoms to close a heterocyclic nucleus or substituted heterocyclic nucleus;Y represents OR.sup.4 or NR.sup.5 R.sup.6 or CN;R.sup.4 represents hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, SO.sub.2 R.sup.7, COR.sup.7, CSR.sup.7, POR.sup.7 R.sup.8 ;R.sup.5 and R.sup.6 each independently has one of the significances given to R.sup.4 or represent substituted or unsubstituted amino, or R.sup.5 and R.sup.
    Type: Grant
    Filed: October 20, 1994
    Date of Patent: November 21, 1995
    Assignee: AGFA-GAVAERT, N.V.
    Inventor: Luc J. Vanmaele
  • Patent number: 5466813
    Abstract: Imine dyes useful in photographic materials have the formula ##STR1## wherein R.sup.1, E.sup.1, E.sup.2, L.sup.1, L.sup.2, L.sup.3,D and m are defined as in the specification.Solid particle dispersions of dyes of formula (I) that contain at least one base-ionizable functional group such as carboxy, sulfonamido, or sulfamoyl are useful as filter dyes in photographic elements.
    Type: Grant
    Filed: July 20, 1993
    Date of Patent: November 14, 1995
    Assignee: Eastman Kodak Company
    Inventors: Donald R. Diehl, Margaret J. Helber, Hugh Williamson
  • Patent number: 5142089
    Abstract: Dye corresponding to the following formula - ##STR1## wherein Z represents CN, COOR.sup.1 or CONR.sup.2 R.sup.3 ;R.sup.1, R.sup.2 and R.sup.3 each independently represents hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, or R.sup.2 and R.sup.3 together represent the necessary atoms to close a heterocyclic nucleus or substituted heterocyclic nucleus;Y represents OR.sup.4 or NR.sup.5 R.sup.6 or CN;R.sup.4 represents hydrogen, substituted or unsubstituted or unsubstituted aryl, SO.sub.2 R.sup.7, COR.sup.7, CSR.sup.7, POR.sup.7 R.sup.8 ;R.sup.5 and R.sup.6 each independently has one of the significances given to R.sup.4 or represents substituted or unsubstituted amino, or R.sup.5 and R.sup.6 together represent the necessary atoms to close a heterocyclic nucleus or substituted heterocyclic nucleus, including a heterocyclic nucleus with an aliphatic or aromatic ring fused-on;R.sup.7 and R.sup.
    Type: Grant
    Filed: June 4, 1991
    Date of Patent: August 25, 1992
    Assignee: Agfa-Gevaert, N.V.
    Inventor: Luc J. Vanmaele
  • Patent number: 4782073
    Abstract: The invention relates to novel amides of [(5,6-dichloro-3-oxo-9a-substituted-2,3,9,9a-tetrahydrofluoren-7-yl)oxy]ac etic acids, their derivatives, and their salts. The compounds are useful for the treatment and prevention of injury to the brain and of edema due to head trauma, stroke (particularly ischemic), arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, the neurological problems caused by AIDS, cerebral hemorrhage, cerebral tumors, encephalomyelitis, spinal cord injury, hydroephalus, post-operative brain injury trauma, edema due to cerebral infections, various brain concussions and elevated intracranial pressure.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: November 1, 1988
    Assignee: Merck & Co., Inc.
    Inventor: Edward J. Cragoe, Jr.
  • Patent number: 4728665
    Abstract: An amide derivative of the formula (I): ##STR1## or a tautomeric form thereof, wherein R is a phenyl group substituted in the 4-position by a group of R.sup.1 XCH.sub.2-, where R.sup.1 is C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl, C.sub.3 -C.sub.4 alkynyl, C.sub.1 -C.sub.4 alkylcarbonyl, or H, and X is oxygen or sulphur;E is CN, or CSNH.sub.2, or CONH.sub.2 ; andY is 1-pyrazolyl or 2-furyl. Compositions and processes for using these derivatives to combat plant fungi are also disclosed.
    Type: Grant
    Filed: August 23, 1985
    Date of Patent: March 1, 1988
    Assignee: Imperial Chemical Industries PLC
    Inventors: Margaret C. Shephard, Patrick J. Crowley