Plural Sulfonate Groups Attached Indirectly To Each Other By Nonionic Bonding Patents (Class 558/46)
  • Patent number: 11292763
    Abstract: A method includes combining first components including at least one of CF2?CF—CF2—OSO2Cl or CF2?CF—CF2—OSO2CF3, a polyfluorinated compound having at least one ketone or carboxylic acid halide, and fluoride ion to provide a compound comprising at least one perfluorinated allyl ether group. A method includes combining second components including B(OSO2Cl)3 and hexafluoropropylene to provide CF2?CF—CF2—OSO2Cl. Another method includes combining second components including M(OSO2CF3)3 and hexafluoropropylene at a temperature above 0° C. to provide CF2?CF—CF2—OSO2CF3, wherein M is Al or B. The compound CF2?CF—CF2—OSO2Cl is also provided.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: April 5, 2022
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Klaus Hintzer, Markus E. Hirschberg, Romana Pajkert, Gerd-Volker Röschenthaler, Sergey N. Tverdomed
  • Patent number: 9012230
    Abstract: The present disclosure relates to a sulfonated benzene compound emitting fluorescence by reaction with hydrogen peroxide, aqueous-dispersed fluorescent nanoprobes applicable for real-time detection of hydrogen peroxide, and a fluorescent nanoprobe fabrication method. The fluorescent nanoprobe contains the following sulfonated benzene compound and water.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: April 21, 2015
    Assignee: Korea Institute of Science and Technology
    Inventors: Sehoon Kim, Ick Chan Kwon, Jai Kyeong Kim, Chang-Keun Lim, Jeongyun Heo
  • Publication number: 20150086911
    Abstract: An actinic ray-sensitive or radiation-sensitive resin composition includes; a compound (A) which generates an acid by irradiation with actinic rays or radiation, wherein the acid is linked with a group represented by the following general formula (M) through covalent bonding. In the formula, Y1 and Y2 each independently represent a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aryl group, or an acyl group. Z represents a hydrogen atom or a substituent.
    Type: Application
    Filed: December 4, 2014
    Publication date: March 26, 2015
    Applicant: FUJIFILM Corporation
    Inventors: Takuya TSURUTA, Tomotaka TSUCHIMURA, Tadeteru YATSUO
  • Patent number: 8865929
    Abstract: A method for preparing a polymerizable monomer-dye compound is provided in which a monomer, a reactive dye, and base are combined under substantially anhydrous reaction conditions to form the polymerizable monomer-dye compound, wherein the monomer comprises a pendant reactive group that covalently links to the reactive dye to form the monomer-dye compound.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: October 21, 2014
    Assignee: CooperVision International Holding Company, LP
    Inventors: Yuan Xu, Charlie Chen, Charles A. Francis, Shane Mao, Hong Xue, Xining Zhang
  • Publication number: 20140275474
    Abstract: Metal ligand-containing prepolymers, compositions containing metal ligand-containing prepolymers, methods of synthesizing metal ligand-containing prepolymers and the use of metal ligand-containing prepolymers in aerospace sealant applications are disclosed. The metal ligand-containing prepolymers have metal ligands incorporated into the backbone of the prepolymer. Cured sealant compositions comprising the metal ligand-containing prepolymers exhibit enhanced properties suitable for aerospace sealant applications.
    Type: Application
    Filed: October 29, 2013
    Publication date: September 18, 2014
    Applicant: PRC-DeSoto International, Inc.
    Inventors: Chandra Rao, Jun Deng, Renhe Lin
  • Publication number: 20140199601
    Abstract: The present invention aims to provide an additive for a non-aqueous electrolyte solution with excellent storage stability capable of forming a stable SEI on the surface of an electrode to improve cell performance such as a cycle performance, a discharge/charge capacity, and internal resistance, when the additive is used for electrical storage devices such as non-aqueous electrolyte solution secondary cells and electric double layer capacitors. The present invention also aims to provide a non-aqueous electrolyte solution containing the additive for a non-aqueous electrolyte solution and to provide an electrical storage device using the non-aqueous electrolyte solution.
    Type: Application
    Filed: July 6, 2012
    Publication date: July 17, 2014
    Applicant: SUMITOMO SEIKA CHEMICALS CO., LTD.
    Inventors: Tomohiro Onozuka, Shohei Fujimoto, Koji Fujita
  • Publication number: 20140154587
    Abstract: The present invention provides a nonaqueous electrolytic solution capable of improving electrochemical characteristics in a broad temperature range, such as low-temperature cycle properties and low-temperature discharge properties after high-temperature storage, and provides an energy storage device using the nonaqueous electrolytic solution. The invention includes (1) a nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, which comprises from 0.001 to 10% by mass of a compound represented by the following general formula (I), and (2) an energy storage device comprising a positive electrode, a negative electrode, and a nonaqueous electrolytic solution of an electrolyte salt dissolved in a nonaqueous solvent, wherein the nonaqueous electrolytic solution is the nonaqueous electrolytic solution of (1).
    Type: Application
    Filed: August 7, 2012
    Publication date: June 5, 2014
    Applicant: UBE INDUSTRIES, LTD
    Inventors: Koji Abe, Kei Shimamoto
  • Patent number: 8716513
    Abstract: Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof. Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R1's and T are as described in claim 1) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R3 to R5 are as described in claim 1), and a disulfonic acid ester represented by a general formula [1?] (in the formula, two R16's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5).
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: May 6, 2014
    Assignee: Wako Pure Chemical Industries, Ltd.
    Inventors: Kuniaki Okamoto, Tsutomu Watahiki, Motoshige Sumino
  • Patent number: 8637713
    Abstract: A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: January 28, 2014
    Assignee: Novartis AG
    Inventors: Christian Mathes, Michael Foulkes, Martin Kesselgruber
  • Publication number: 20140012028
    Abstract: A compound represented by following formula (I): A-L-{D1-(E)q-D2-(B)m—Z1—R}p. In the formula, A represents a p-valent chain or cyclic residue; L represents a single bond or a divalent linking group; p represents an integer of 2 or more; D1 represents a carbonyl group (—C(?O)—) or a sulfonyl group (—S(?O)2—); D2 represents a carbonyl group (—C(?O)—), a sulfonyl group (—S(?O)2—), a carboxyl group (—C(?O)O—), a sulfonyloxyl group (—S(?O)2O—), a carbamoyl group (—C(?O)N(Alk)-) or a sulfamoyl group (—S(?O)2N(Alk)-); E represents a divalent group; and R represents a hydrogen atom, a substituted or non-substituted C8 or longer alkyl group, a perfluoroalkyl group or a trialkylsilyl group.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 9, 2014
    Applicant: FUJIFILM Corporation
    Inventors: Saisuke WATANABE, Hiyoku Nakata, Ken Kawata
  • Publication number: 20130338160
    Abstract: The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of medical conditions including androgen associated conditions, androgen associated inflammation, a wound (the compounds assist with wound healing), acne, rheumatoid arthritis, psoriasis, rosacea, and alopecia; Kennedy's disease (spinal and bulbar muscular atrophy, or SBMA), polyglutamine-mediated motor neuron degeneration; cancers such as prostate cancer, bladder cancer, breast cancer, ovarian cancer, hepatocellular (liver) cancer, and pancreatic cancer; and other medical conditions described herein. Treatment of such medical conditions includes administering to an individual suffering from a medical condition describe herein, a therapeutically effective amount of any of the disclosed compounds, their derivatives, or pharmaceutical compositions thereof.
    Type: Application
    Filed: June 18, 2013
    Publication date: December 19, 2013
    Inventors: Charles SHIH, Qian Shi, Hui-kang Wang
  • Publication number: 20130224578
    Abstract: The present invention relates to a nonaqueous electrolyte solution comprising a lithium salt and a nonaqueous organic solvent, wherein the nonaqueous electrolyte solution comprises a specific sulfonic acid ester.
    Type: Application
    Filed: April 18, 2013
    Publication date: August 29, 2013
    Applicant: MITSUBISHI CHEMICAL CORPORATION
    Inventor: MITSUBISHI CHEMICAL CORPORATION
  • Publication number: 20130096337
    Abstract: A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.
    Type: Application
    Filed: December 5, 2012
    Publication date: April 18, 2013
    Applicant: Novartis AG
    Inventor: Novartis AG
  • Patent number: 8415508
    Abstract: A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: April 9, 2013
    Assignee: Novartis AG
    Inventors: Christian Mathes, Michael Foulkes, Martin Kesselgruber
  • Publication number: 20120277332
    Abstract: One embodiment includes methods of adding two sulfonic acid groups to molecules having at least two cyclic groups.
    Type: Application
    Filed: April 29, 2011
    Publication date: November 1, 2012
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Thomas J. Chapaton, Tenneille Weston Capehart, Gail Capehart, Armand Soldera, Claude Spino, Riadh Zriba
  • Publication number: 20120276651
    Abstract: The present disclosure relates to a sulfonated benzene compound emitting fluorescence by reaction with hydrogen peroxide, aqueous-dispersed fluorescent nanoprobes applicable for real-time detection of hydrogen peroxide, and a fluorescent nanoprobe fabrication method. The fluorescent nanoprobe contains the following sulfonated benzene compound and water.
    Type: Application
    Filed: January 31, 2012
    Publication date: November 1, 2012
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sehoon KIM, Ick Chan Kwon, Jai Kyeong Kim, Chang-Keun Lim, Jeongyun Heo
  • Publication number: 20120258399
    Abstract: A radiation-sensitive resin composition includes a compound shown by a following general formula (A), a solvent and a resin having an acid-labile group. Each of R1 and R2 independently represents a substituted or unsubstituted monovalent hydrocarbon group having 1 to 25 carbon atoms. Each of X and Z independently represents a substituted or unsubstituted divalent hydrocarbon group having 1 to 25 carbon atoms. Y represents a single bond or the like. n represents an integer from 0 to 5.
    Type: Application
    Filed: June 18, 2012
    Publication date: October 11, 2012
    Applicant: JSR Corporation
    Inventor: Ken MARUYAMA
  • Publication number: 20120208850
    Abstract: The invention relates to methods, compounds, and compositions for delivering 1,3-propanedisulfonic acid (1,3PDS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 1,3PDS, either in vitro or in vivo. The invention also relates to sulfonate ester prodrugs of 1,3PDS as well as Gemini dimmers and oligomers of 1,3PDS for the prevention or treatment of associated diseases and conditions.
    Type: Application
    Filed: August 6, 2010
    Publication date: August 16, 2012
    Applicant: BELLUS HEALTH INC.
    Inventors: Xianqi Kong, Nigel Levens, Abderrahim Bouzide, Stephane Ciblat, Richard Frenette, Johanne Renaud
  • Patent number: 8227624
    Abstract: A photoacid generator which can generate an acid efficiently when energy was absorbed, is excellent in the developing property and can form fine patterns, and a cationic polymerization initiator excellent in curability are provided; and a resist composition and a cationically polymerizable composition using them are provided. An aromatic sulfonium salt compound represented by the General Formula (I) below: (wherein each of E1 to E4 independently represents a substituent represented by the General Formula (II) below or the General Formula (III) below). Preferably, in the General Formula (I), r and s are 0; m and n are 0; or n and r are 0, and more preferably, one of m and s in the General Formula (I) is 1.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: July 24, 2012
    Assignee: Adeka Corporation
    Inventors: Tetsuyuki Nakayashiki, Kentaro Kimura
  • Publication number: 20120130107
    Abstract: Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof. Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R1's and T are as described in claim 1) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R3 to R5 are as described in claim 1), and a disulfonic acid ester represented by a general formula [1?] (in the formula, two R16's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5).
    Type: Application
    Filed: August 5, 2010
    Publication date: May 24, 2012
    Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.
    Inventors: Kuniaki Okamoto, Tsutomu Watahiki, Motoshige Sumino
  • Publication number: 20120046247
    Abstract: This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.
    Type: Application
    Filed: August 16, 2011
    Publication date: February 23, 2012
    Inventors: Charles C-Y Shih, Toshio Kitamura, Qian Shi, Toshiyuki Kawashima, Hui-Kang Wang
  • Publication number: 20110236827
    Abstract: The present invention provides a resin obtained by reacting a compound represented by the formula (I): wherein R1 represents a hydrogen atom or a C1-C6 alkyl group, R2, R3 and R4 each independently represents a C1-C6 alkyl group and R1, R2, R3, R4 and A1 are bonded to form a ring, A1 represents a C1-C20 saturated hydrocarbon group in which one or more —CH2— can be replaced by —O—, B1 and B2 each independently represent a C1-C6 alkylene group, L1 and L2 each independently represent a halogen atom, —O—CH?CH2, —O—CH?CH(CH3) or —O—SO2—R? in which R? represents a C1-C6 alkyl group or a C6-C20 aryl group, with a polyhydric phenol compound.
    Type: Application
    Filed: March 23, 2011
    Publication date: September 29, 2011
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Ichiki TAKEMOTO, Nobuo ANDO
  • Publication number: 20110152540
    Abstract: A photoacid generator which can generate an acid efficiently when energy was absorbed, is excellent in the developing property and can form fine patterns, and a cationic polymerization initiator excellent in curability are provided; and a resist composition and a cationically polymerizable composition using them are provided. An aromatic sulfonium salt compound represented by the General Formula (I) below: (wherein each of E1 to E4 independently represents a substituent represented by the General Formula (II) below or the General Formula (III) below). Preferably, in the General Formula (I), r and s are 0; m and n are 0; or n and r are 0, and more preferably, one of m and s in the General Formula (I) is 1.
    Type: Application
    Filed: August 4, 2008
    Publication date: June 23, 2011
    Inventors: Tesuyuki Nakayashiki, Kentaro Kimura
  • Publication number: 20100292481
    Abstract: A method for producing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of a nickel compound, a ligand, a manganese salt and a metal reducing agent.
    Type: Application
    Filed: December 17, 2008
    Publication date: November 18, 2010
    Inventors: Seiji Oda, Takashi Kamikawa
  • Publication number: 20100168229
    Abstract: A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drug substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.
    Type: Application
    Filed: December 17, 2009
    Publication date: July 1, 2010
    Inventors: Christian Mathes, Michael Foulkes, Martin Kesselgruber
  • Publication number: 20100094038
    Abstract: The present invention provides a method of preparing a sulfonyl ether comprising the steps of: v) reacting a sulfonic acid with an anhydride, under continuous vacuum distillation conditions, to form a carboxysulfonate; vi) reacting the carboxysulfonate with an optionally substituted cycloalkane ring containing at least 3 heteroatoms to form a sulfonyl ether pre-mix comprising a sulfonyl ether and at least two additional reaction products each containing at least one ether linkage; vii) subjecting the pre-mix to continuous vacuum distillation conditions to remove at least some of the additional reaction products from the sulfonyl ether pre-mix to provide a crude sulfonyl ether product; and viii) purifying the crude sulfonyl ether product.
    Type: Application
    Filed: January 8, 2008
    Publication date: April 15, 2010
    Applicant: PHOENIX CHEMICALS LIMITED
    Inventors: Antony Warr, Peter McCormack, Jonathan Eddolls, Elliot Latham
  • Publication number: 20100036135
    Abstract: The present invention is directed to a process for preparing certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The compounds are useful in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
    Type: Application
    Filed: July 7, 2006
    Publication date: February 11, 2010
    Applicant: MERCK & CO., INC.
    Inventors: Jeffrey T. Kuethe, Jingjun Yin, Mark A. Huffman, Michel Journet
  • Patent number: 7569714
    Abstract: A quaternary onium aromatic sulfonate represented by the formula: wherein each R1 independently comprises substituted or unsubstituted, aliphatic or aromatic, hydrocarbyl, carbocyclic or heterocyclic radicals, each X is selected from the group consisting of phosphorus and nitrogen; wherein “a” has a value of 0, 1 or 2, and “b” has a value of 0 or 1 with the proviso that (a+b) is equal to 1 or 2; G1 is an aromatic group; E comprises a bis(carbonyloxyalkyl) polydiorganosiloxane, a bis(carbonyloxyaryl) polydiorganosiloxane, and an ether linkage; each Y1 independently comprises hydrogen, a monovalent hydrocarbon group, alkenyl, allyl, halogen, bromine, chlorine; nitro; and OR, wherein R is a monovalent hydrocarbon group; “q” represents any integer from and including zero through the number of positions on G1 available for substitution; “t” represents an integer equal to at least one; “s” represents an integer equal to either zero or one; and “u” represents any integer including zero; with the proviso that whe
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: August 4, 2009
    Assignee: Sabic Innovative Plastics IP B.V.
    Inventors: Sanjoy Kumar Chowdhury, Prakash P. Wadgaonkar, Theodorus Lambertus Hoeks, Suresh K. Rajaraman, Bhimrao D. Sarwade, Chilukuri Ver Avadhani
  • Patent number: 7531290
    Abstract: Sulfonate salts have the formula: R1SO3—CH(Rf)—CF2SO3?M+ wherein R1 is alkyl or aryl, Rf is H or trifluoromethyl, and M+ is a Li, Na, K, ammonium or tetramethylammonium ion. Onium salts, oximesulfonates and sulfonyloxyimides and other compounds derived from these sulfonate salts are effective photoacid generators in chemically amplified resist compositions.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: May 12, 2009
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Katsuhiro Kobayashi, Youichi Ohsawa, Takeshi Kinsho, Takeru Watanabe
  • Publication number: 20090004485
    Abstract: An organic material having a 6-member ring structure represented by the following formulae (I), wherein: ring A, ring B, and ring C each include substituted or un-substituted aromatic rings comprising 6 to 60 carbon atoms, or substituted or un-substituted heteroaromatic rings comprising 4 to 60 carbon atoms, and ring A and ring C form a fused aromatic or heteroaromatic structure; X is a carbon atom, a nitrogen atom, a sulfur atom, a silicon atom, an oxygen atom, a phosphorus atom, a selenium atom, or a germanium atom.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 1, 2009
    Inventors: Shiying Zheng, Liang-Sheng Liao
  • Publication number: 20080227978
    Abstract: A process for converting a carbonyl group within a substrate to a chiral alcohol moiety comprising reacting the carbonyl containing substrate with an organoaluminium reagent in the presence of a Group 5-12 transition metal based catalyst which is complexed with a chiral ligand; novel chiral ligands and organoluminium reagents, a chiral ligand or organoaluminium reagent for use in the process.
    Type: Application
    Filed: January 26, 2006
    Publication date: September 18, 2008
    Inventor: Simon Woodward
  • Patent number: 6858736
    Abstract: The present invention relates to novel hexa-arm polyethylene glycol (6-arm PEG) and its derivatives. The core of 6-arm PEG derivatives is sorbitol and the end groups can be derivatized into many different reactive functionalities that are useful in conjugating with many different targets. The present invention also provides a biodegradable polymeric hydrogel-forming composition comprising the 6-arm PEG and its derivatives, and methods of using such 6-arm PEG derivatives as surgical or biological implants or sealants.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: February 22, 2005
    Assignee: SunBio, Inc.
    Inventors: Kwang Nho, Hyun Chang-min, Jung-Hun Lee, In-Kyung Kim, Young-Kyoung Pak
  • Patent number: 6787242
    Abstract: Adhesion promoters for polymer coatings on metals are articulated into at least two head groups connected by a hydrocarbon spacer group. One head group reacts particularly well with polymer molecules. Other head groups form a durable bond with a metal surface. The length of the spacer group is such that a substance deposited in a substance layer on a metallic surface of a body or particle has hydrophobic properties. Suitable adhesion promoters can be sulfur compounds, amino compounds, hydroxyl or carbonyl compounds. A plastic composite body, a compound and a process of preparing a compound are also provided.
    Type: Grant
    Filed: June 4, 2003
    Date of Patent: September 7, 2004
    Assignee: Infineon Technologies AG
    Inventors: Alexandra Atzesdorfer, Rainer Müller, Klaus Heckmann, Friederike Bauer
  • Publication number: 20030191335
    Abstract: Described are bis(perfluoro-n-alkane-sulfonate) compounds, methods for preparing these compounds and use of these compounds, for example as starting materials for the synthesis of chiral and phosphine ligands for transition metal catalysts.
    Type: Application
    Filed: August 9, 2001
    Publication date: October 9, 2003
    Applicant: Merck Patent GmbH
    Inventors: Andreas Wachtler, Karl-Heinz Derwenskus, Andreas Meudt
  • Patent number: 6504042
    Abstract: Spiro compounds of the formula I in which &psgr; is C, Si, Ge or Sn and K1 and K2 independently of one another are conjugated systems, are suitable as materials in nonlinear optics.
    Type: Grant
    Filed: October 10, 1996
    Date of Patent: January 7, 2003
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Donald Lupo, Josef Salbeck
  • Publication number: 20020077493
    Abstract: Onium salts of arylsulfonyloxybenzenesulfonate anions with iodonium or sulfonium cations are novel. A chemically amplified resist composition comprising the onium salt as a photoacid generator is suited for microfabrication, especially by deep UV lithography because of many advantages including improved resolution, improved focal latitude, minimized line width variation or shape degradation even on long-term PED, minimized debris after coating, development and peeling, and improved pattern profile after development.
    Type: Application
    Filed: October 23, 2001
    Publication date: June 20, 2002
    Applicant: Shin-Etsu Chemical Co., Ltd.
    Inventors: Youichi Ohsawa, Jun Watanabe, Kazunori Maeda
  • Patent number: 6399806
    Abstract: A process for producing a binaphthol bistriflate, 2,2′-bis(trifluoromethanesulfonyloxy)-1,1′-binaphthyl, includes reacting 1,1′-bi-2-naphthol with trifluoromethanesulfonyl fluoride, in a polar solvent, in the presence of an organic base. The reaction proceeds quickly at a low temperature by using a polar solvent as the reaction solvent, while the reaction pressure does not become high. The polar solvent is preferably at least one selected from N,N-dimethylformamide, N,N-dimethylacetoamide, 1-methyl-2-pyrrolidinone, and acetonitrile.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: June 4, 2002
    Assignee: Central Glass Company Limited
    Inventors: Akihiro Ishii, Mikio Ujiie, Yokusu Kuriyama, Mitsuru Tanuma
  • Patent number: 6388022
    Abstract: The present invention provides a linker binding carrier for organic synthesis represented by the formula: —Z—W—(SO2X)m wherein  is a carrier, X is a leaving group, Y is a bond or spacer, Z is a bivalent group, when Z is a bivalent electron attractive group, W is an aromatic ring which may be substituted and when Z is a bivalent non-electron attractive group, W is an aromatic ring which is substituted by an electron attractive group and may be further substituted and m is 1 or 2, or a salt thereof, which is useful for synthesizing a novel organic compound.
    Type: Grant
    Filed: August 30, 1999
    Date of Patent: May 14, 2002
    Assignee: Takeda Chemical Industires, Ltd.
    Inventors: Katsunori Nagai, Tetsuo Miwa
  • Patent number: 6380445
    Abstract: Soluble poly(bis-9,9′-fluorenes) comprise identical or different structural repeating units of the formula I, where the two R1s are, independently of one another, H, C1-C18alkyl, C6-C14aryl, C7-C15aralkyl, C1-C18alkoxy, R2—(O—CnH2n)m—O—, C1-C18alkylthio, C1-C18dialkylamino, —C(O)OH, —C(O)O—C1-C18alkyl, —C(O)—N(C1-C18alkyl)2, —SO3H, —SO3—C1-C18alkyl, —SO2—N(C1-C18alkyl)2, C1-C17alkyl-C(O)—O— or C1-C17alkyl-C(O)—, R2 is H or C1-C12alkyl, n is from 2 to 6 and m is from 1 to 12. The polymers can be used either alone or in admixture with at least one additional fluorophore whose absorption band overlaps the emission band (fluorescent emission) of the polymer of the formula I as active radiative layer for light-emitting diodes, VDUs and display elements.
    Type: Grant
    Filed: May 9, 2000
    Date of Patent: April 30, 2002
    Assignee: Vantico Inc.
    Inventors: Ralf-Roman Rietz, Wolfgang Wernet
  • Patent number: 6365625
    Abstract: This invention pertains to the discovery that condensation polymers of an aldehyde and aromatic sulfonic acids and fractions thereof, such as formaldehyde naphthalenesulfonic acid condensation polymers, can abrogate HIV gp120 binding to CD4, as demonstrated in CD4/gp120 binding assays. In addition to gp120 binding inhibition, the compounds have been shown to inhibit HIV-induced syncytia formation and infectivity of CD+ cells. The use of this compound has been shown to be non-cytotoxic and non-inhibitory to antigen induced T lymphocyte proliferation. Based on these findings, these compounds can be used as a therapeutic agent for the treatment of acquired immunodeficiency syndrome (AIDS), as well as AIDS-related complex (ARC), AIDS-related dementia and non-symptomatic HIV infection. The compounds can also be used to treat blood preparations.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: April 2, 2002
    Assignee: Procept, Inc.
    Inventors: Shyam K. Singh, Raymond J. Patch, Peter V. Pallai, Edith A. Neidhardt, Gerard P. Palace, Kevin J. Willis, Theresa M. Sampo, Kevin W. McDonald, Zhan Shi
  • Patent number: 6214435
    Abstract: A novel aminium compound exhibiting excellent solubility for solvents and high safety in terms of handling and environment is provided. An aminium compound represented by the following formula (1): wherein R1 represents substituted or unsubstituted alkyl and A2− represents a divalent organic anion.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: April 10, 2001
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Masao Onishi, Tadayuki Kiyoyanagi
  • Patent number: 6124474
    Abstract: A process for preparing chiral isomers of N-protected 2-azetidinemethanol compounds, particularly N-(phenylmethyl)-2-azetidinemethanol and N-BOC-2-azetidinemethanol, and especially the (R)-isomers thereof, as well as O-substituted derivatives thereof.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: September 26, 2000
    Assignee: Abbott Laboratories
    Inventors: Anthony R. Haight, John E. Lallaman, Gregory S. Wayne
  • Patent number: 6075050
    Abstract: This invention pertains to the discovery that condensation polymers of an aldehyde and aromatic sulfonic acids and fractions thereof, such as formaldehyde naphthalenesulfonic acid condensation polymers, can abrogate HIV gp120 binding to CD4, as demonstrated in CD4/gp120 binding assays. In addition to gp120 binding inhibition, the compounds have been shown to inhibit HIV-induced syncytia formation and infectivity of CD+ cells. The use of this compound has been shown to be non-cytotoxic and non-inhibitory to antigen induced T lymphocyte proliferation. Based on these findings, these compounds can be used as a therapeutic agent for the treatment of acquired immunodeficiency syndrome (AIDS), as well as AIDS-related complex (ARC), AIDS-related dementia and non-symptomatic HIV infection. The compounds can also be used to treat blood preparations.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 13, 2000
    Assignee: Procept, Inc.
    Inventors: Shyam K. Singh, Raymond J. Patch, Peter V. Pallai, Edith A. Neidhardt, Gerard P. Palace, Kevin J. Willis, Theresa M. Sampo, Kevin W. McDonald, Zhan Shi
  • Patent number: 6020513
    Abstract: The instant invention provides dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods for use in the treatment of bone loss or bone resorption.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: February 1, 2000
    Assignee: Eli Lilly and Company
    Inventors: Henry Uhlman Bryant, Thomas Alan Crowell, Charles David Jones
  • Patent number: 5814110
    Abstract: Distillate fuel is treated with additives whose structure match the crystal planes of the wax which crystallizes from the fuel to produce crystals below 4000 nanometres in size, suitable additive include novel sulpho-carboxylic materials particularly their esters and amine derivatives such as the amine salts and/or amides of ortho-sulpho benzoic acid.
    Type: Grant
    Filed: November 23, 1994
    Date of Patent: September 29, 1998
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Kenneth William Bartz, Jacqueline Dawn Bland, David Paul Gillingham, Richard Dix Kerwood, Edwin William Lehmann, Kenneth Lewtas, John Edward Maddox, Albert Rossi, Robert Dryden Tack
  • Patent number: 5780644
    Abstract: Branched, dendrimeric-type macromolecules composed essentially of a central nucleus and of a series of polyoxaalkyl chains that depart from said nucleus and spread into the surrounding space branching in a cascade fashion useful as carriers of drugs, contrast agents, etc.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: July 14, 1998
    Assignee: Dibra S.p.A.
    Inventors: Luigia Gozzini, Monica Muttoni, Christoph DeHaen
  • Patent number: 5763636
    Abstract: Polymers containing spiro atoms which can be used as electroluminescence materials, suitable for use in ligerting or display devices, and which improve the property profile of these devices. Specifically, a conjugated polymer comprising structural units of the formula (I), ##STR1## where the symbols and indices have the following meanings: D, E, F.sup.1, G are identical or different, and are --CR.sup.1 R.sup.1 --, --O--, --S--, --NR.sup.3 -- or a chemical bond;Ar.sup.1, Ar.sup.2 are carbocycles or heterocycles;U.sup.1, V.sup.1 are identical or different, and are --CR.sup.5.dbd.CR.sup.6 --, --CR.sup.7 R.sup.8 --, --CR.sup.9 R.sup.10 --CR.sup.11 R.sup.12 --, --NR.sup.13 --, --SiR.sup.14 R.sup.15 --, --O--, --S--, --SO--, --SO.sub.2 --, --CO-- or a chemical bond;Ar.sup.5, Ar.sup.6, X, Y.sup.1 are identical or different, and are cyclic or acyclic, conjugated hydrocarbons and X and/or y.sup.1 can also be H or R.sup.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: June 9, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Willi Kreuder, Hubert Spreitzer
  • Patent number: 5750577
    Abstract: Novel medicinally-useful compounds are provided herein. These compounds include isomeric cyclic tetramers of formaldehyde and 1-naphthol, and the derivatives or analogues of such cyclic tetramers, and linear oligomers of chromotropic acid, or its derivatives or analogues with naphthalene.
    Type: Grant
    Filed: December 5, 1996
    Date of Patent: May 12, 1998
    Assignee: Seabright Corporation Limited
    Inventor: Paris Georghiou
  • Patent number: 5716756
    Abstract: Sulfonic acid esters are used as (a) compounds for forming a strong acid on irradiation in radiation-sensitive, positive or negative working mixtures also comprising (b) either a compound with at least one acid-decomposable C--O--C or C--O--Si bond (for positive working mixtures) or a compound with at least acid-cross-linkable groups (for negative working mixtures) and c) a binder which is insoluble in water but soluble or at least swellable in aqueous alkaline solutions, wherein said sulfonic acid esters are formula?R.sup.1 --CR.sup.2 (CF.sub.3)--O--SO.sub.2 --!.sub.n R.sup.3(I)orR.sup.1 ?--CR.sup.2 (CF.sub.3)--O--SO.sub.2 --R.sup.3 !m (II)wherein R.sup.1, R.sup.2, R.sup.3, n and n are defined with the body of the disclosure. These mixtures are particularly suitable for exposure to deep UV radiation in the formation of recording materials suitable for the production of photoresists, electronic components, and printing plates.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: February 10, 1998
    Assignees: Hoechst Aktiengesellschaft, Herberts GmbH
    Inventors: Georg Pawlowski, Walter Spiess, Horst Roeschert, Wolfgang Appel, Walter Herr
  • Patent number: 5708018
    Abstract: Compounds and their pharmaceutically acceptable salts suitable for treating central nervous system disorders associated with the dopamine D3 receptor activity of Formula I: ##STR1## wherein R.sub.1 and R.sub.2 are independently chosen from hydrogen, C.sub.1 -C.sub.8 alkyl, OCH.sub.3, OH, OSO.sub.2 CF.sub.3, OSO.sub.2 CH.sub.3, SOR.sub.5, CO.sub.2 R.sub.5, CONH.sub.2, CONR.sub.5 R.sub.6, COR.sub.5, CN, SO.sub.2 NH.sub.2, SO.sub.2 NR.sub.5 R.sub.6, SO.sub.2 R.sub.5, --OCO--(C.sub.1 -C.sub.6 alkyl), --NCO--(C.sub.1 -C.sub.6 alkyl), --CH.sub.2 O--(C.sub.1 -C.sub.6 alkyl), --CH.sub.2 OH, --CO-Aryl, --NHSO.sub.2 -Aryl, --NHSO.sub.2 --(C.sub.1 -C.sub.6 alkyl), phthalimide, thiophenyl, pyrrol, pyrrolinyl, oxazolyl, or R.sub.1 and R.sub.2 together form --O(CH.sub.2).sub.1-2 O-- or --(CH.sub.2).sub.3-6 -- (except that only one of R.sub.1 and R.sub.2 can be hydrogen or OH in any such compound); R.sub.3 and R.sub.4 are independently chosen from C.sub.2 -C.sub.4 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.3 -C.sub.
    Type: Grant
    Filed: February 2, 1996
    Date of Patent: January 13, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventors: Susanne R. Haadsma-Svensson, Bengt R. Andersson, Clas A. Sonesson, Chiu-Hong Lin, R. Nicholas Waters, Kjell A. I. Svensson, Per A. E. Carlsson, Lars O. Hansson, N. Peter Stjernlof