Carbon Bonded Directly To The Nitrogen Of The Imidate Group (e.g., N Cyanoimidates, Etc.) Patents (Class 558/9)
  • Patent number: 8334059
    Abstract: An organic electroluminescence device includes an anode; a cathode; and at least one organic layer, which includes a light-emitting layer being provided between the anode and the cathode and containing at least one light-emitting material, and which contains at least one compound represented by formula (I): wherein each of A11, A12, A13, A14 and A15 represents an N atom or C—R11, and the number of N atoms represented by A11 to A15 is 1 or 2; R11 represents a hydrogen atom or a substituent, and at least one of R11 represents an aryl group or an aromatic heterocyclic group; Q11 represents a monocyclic aryl group or an aromatic heterocyclic group; R12 represents an alkyl group; and each of n, m and l represents an integer of from 0 to 4, provided that n is 1 or more, n+m is 2 or more, and n+m+l is 4.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: December 18, 2012
    Assignee: UDC Ireland Limited
    Inventor: Eiji Fukuzaki
  • Publication number: 20110319437
    Abstract: The compound (I) or a salt thereof has an excellent controlling activity against pests. Then the compound (I) or a salt thereof is useful for an active ingredient of a pesticidal composition.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 29, 2011
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Shigeyuki ITOH, Atsushi IWATA
  • Patent number: 7705175
    Abstract: Provided is a method for producing an imide ether compound in high yield. The method is characterized in that a nitrile compound, an alcohol, and a hydrogen halide are continuously introduced into a flow reaction device comprising a mixer and a flow reactor, to be subjected to a reaction. Because a reaction proceeds in a ratio of 1:1 by a flow reactor, selectivity is improved and generation of by-products is decreased, and thus an imide ether compound can be efficiently produced.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: April 27, 2010
    Assignee: Nippoh Chemicals Co., Ltd.
    Inventors: Hitoshi Mitsui, Yuichiro Kinoshita, Kazuya Nakagawa
  • Patent number: 7223879
    Abstract: One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming reactions. The subject methods provide improvements in many features of the transition metal-catalyzed reactions, including the range of suitable substrates, reaction conditions, and efficiency.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: May 29, 2007
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L. Buchwald, Xiaohua Huang, Danilo Zim
  • Patent number: 6943267
    Abstract: Compounds of the general formula wherein R is selected from the group consisting essentially of hydrogen, methyl, ethyl, phenyl, a carboxyl, or naphthyl substituted or a carbonyl substituted, alkyl of from 3 to 20 carbon atoms, a mono, bi or tri cyclic aryl or substituted aryl for the inhibition of phosphatase enzymes, including metallophosphatases; and, novel methods for synthesizing such compounds. The methods of use include the administration of an effective amount of the compound to provide effective phosphatase inhibition and therapeutic use to treat or prevent certain diseases, which utilize specific phosphatase enzymes.
    Type: Grant
    Filed: January 16, 2003
    Date of Patent: September 13, 2005
    Assignee: Utah State University
    Inventors: Alvan Carl Hengge, Krzysztof Jerzy Swierczek
  • Patent number: 6825373
    Abstract: A method of preparing a pyrrolotriazin-4-one and a method of preparing the isothiocyanatoformic acid ester derivative which can be used as a reactant in that method of preparing a pyrrolotriazin-4-one. The method of preparing the pyrrolotriazin-4-one includes an addition step of an aminopyrrole derivative and the isothiocyanatoformic compound and a step of ring-closing reaction of a resulting adduct.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: November 30, 2004
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Tetsunori Matsushita
  • Publication number: 20040013974
    Abstract: The invention describes the use of oxime alkyl sulfonate compounds of formula 1 1
    Type: Application
    Filed: July 2, 2003
    Publication date: January 22, 2004
    Inventors: Kurt Dietliker, Martin Kunz, Hitoshi Yamato, Christoph De Leo
  • Patent number: 6656967
    Abstract: The invention provides fungicidal compounds of formula I and salts thereof: wherein the various radicals and substituents are as defined in the description, fungicidal compositions containing them and method for combating fungi which comprises applying these.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: December 2, 2003
    Assignee: Bayer Cropscience SA
    Inventors: Vincent Gerusz, Darren James Mansfield, Joseph Perez, Jean-Pierre Vors
  • Patent number: 6613925
    Abstract: Here is provided a process of preparing an O-alkyl-N-cyanoacetimidate from cyanamide and an orthoacetic acid ester on an industrial scale and in a high yield using an inexpensive apparatus. In preparing an O-alkyl-N-cyanoacetimidate by reaction of an orthoacetic acid ester with cyanamide, the start of the reaction is made in the presence of an alkaline catalyst.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: September 2, 2003
    Assignee: Nippon Carbide Kogyo K.K.
    Inventors: Takehiko Yoshie, Hidenori Nitta, Youichi Fukunishi
  • Patent number: 5942614
    Abstract: The present invention discloses new processes in the preparation of midazolam (VII), ##STR1## a commercially important pharmaceutical, as well a new intermediates in those processes from a known benzophenone (I) starting material.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: August 24, 1999
    Assignee: Pharmacia & Upjohn Company
    Inventor: Joel Edward Huber
  • Patent number: 5831089
    Abstract: The present invention discloses new processes in the preparation of midazolam (VII), ##STR1## a commercially important pharmaceutical, as well a new intermediates in those processes from a known benzophenone (I) starting material.
    Type: Grant
    Filed: May 28, 1997
    Date of Patent: November 3, 1998
    Assignee: Pharmacia & Upjohn Company
    Inventor: Joel E. Huber
  • Patent number: 5616546
    Abstract: Improved automatic dishwashing detergent compositions, especially granular detergents, comprising bleach activators which form multiperacids, especially specific monoquaternary substituted bis(peroxycarbonic) acids, upon perhydrolysis are provided.
    Type: Grant
    Filed: October 23, 1995
    Date of Patent: April 1, 1997
    Assignee: The Procter & Gamble Company
    Inventors: Gregory S. Miracle, Mark R. Sivik
  • Patent number: 5595967
    Abstract: Improved detergent compositions, especially granular detergents, comprising bleach activators which form multiperacids, especially specific monoquaternary substituted bis(peroxycarbonic) acids, upon perhydrolysis are provided.
    Type: Grant
    Filed: October 23, 1995
    Date of Patent: January 21, 1997
    Assignee: The Procter & Gamble Company
    Inventors: Gregory S. Miracle, Mark R. Sivik, Patti J. Kellett
  • Patent number: 5534179
    Abstract: Improved detergent compositions, especially granular detergents, comprising bleach activators which form multiperacids, especially specific monoquaternary substituted bis(peroxycarbonic) acids, upon perhydrolysis are provided.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: July 9, 1996
    Inventors: Gregory S. Miracle, Mark R. Sivik, Patti J. Kellett
  • Patent number: 5534180
    Abstract: Improved automatic dishwashing detergent compositions, especially granular detergents, comprising bleach activators which form multiperacids, especially specific monoquaternary substituted bis(peroxycarbonic) acids, upon perhydrolysis are provided.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: July 9, 1996
    Inventors: Gregory S. Miracle, Mark R. Sivik
  • Patent number: 5484700
    Abstract: Methods for detecting nucleic acids in a sample, using naphthol derivative phosphates, are provided. Nucleic acids present in a sample are contacted with phosphatase, producing a modified phosphatase. A naphthol derivative phosphate is contacted with the modified phosphatase to produce a reaction product. Any reaction product formed is detected by irradiating it with an excited light and detecting a fluorescence emitted from the reaction product. Naphthol derivative phosphates useful in these methods are also provided. Methods for production of naphthol derivative phosphates are also provided.
    Type: Grant
    Filed: December 13, 1991
    Date of Patent: January 16, 1996
    Assignee: Aisin Seiki Kabushiki Kaisha
    Inventors: Satoshi Fujita, Naoto Kagiyama, Masayoshi Momiyama
  • Patent number: 5360810
    Abstract: There is disclosed a compound of the formula (I): ##STR1## wherein X is a hydrogen atom or 1 to 5 substituents which may be the same or different and are selected from the group consisting of a hydrogen atom, alkyl, alkenyl, alkynyl, optionally substituted phenyl, an optionally substituted heterocyclic group, alkoxy, alkenyloxy, alkynyloxy, optionally substituted phenoxy, mono-, di- or tri-substituted halogenoalkyl and a halogen atom; Y is CH or N; m is 0 or 1; A is a group of the formula: ##STR2## (wherein R.sup.1 is a hydrogen atom or alkyl; n is 0 or 1; B is O, S or NR.sup.3 ; R.sup.2 and R.sup.3 are the same or different and are a hydrogen atom, alkyl, alkenyl, alkynyl, phenyl, benzyl, acyl or phenacyl). There are also disclosed the production thereof and an agricultural fungicide containing the compound as an active component.
    Type: Grant
    Filed: March 18, 1993
    Date of Patent: November 1, 1994
    Assignee: Shionogi & Co., Ltd.
    Inventors: Yoshio Hayase, Hideyuki Takenaka, Norihiko Tanimoto, Michio Masuko, Toshihiko Takahashi
  • Patent number: 5237084
    Abstract: Dialkyl (N-cyanoimido) carbonates are prepared in good yield in a non-aqueous solvent by a process which comprises either (a) adding a cyanogen halide at a controlled rate to a reactor containing an unsubstituted or substituted dialkyl imidocarbonate, an inorganic base and/or a trialkyl amine, or (b) by adding a trialkyl amine to a solution of the unsubstituted or substituted dialkyl imidocarbonate and a cyanogen halide. The dialkyl imidocarbonate precursors are prepared by using a stoichiometric ratio (2:1) of alcohol to cyanogen halide in the presence of an acid acceptor and in a non-aqueous solvent.Dialkyl (N-cyanoimido)carbonates are useful as intermediates for pesticides and pharmaceuticals.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: August 17, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Michael A. Oliver, Ward H. Oliver
  • Patent number: 5208351
    Abstract: The present invention provides a process for the preparation of N-cyanoimidocarbonates of the general formula: ##STR1## in which R.sup.1 and R.sup.2 are the same and are alkyl radicals containing up to 4 carbon atoms or R.sup.1 and R.sup.2 are joined together to give an ethylene or propylene chain which is optionally substituted by an alkyl radical containing up to 3 carbon atoms, wherein an imidocarbonate obtained in aqueous alkaline solution from the appropriate alcohol and cyanogen chloride is added with an acid to an aqueous solution of cyanamide in such a manner that the reaction mixture has a pH value of from 3 to 8.
    Type: Grant
    Filed: July 15, 1992
    Date of Patent: May 4, 1993
    Assignee: SKW Trostberg Aktiengesellschaft
    Inventors: Franz Thalhammer, Stefan Weiss
  • Patent number: 5189060
    Abstract: Novel insecticides have the formula ##STR1## in which R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy or C.sub.1 -C.sub.4 haloalkylthio;R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy or C.sub.1 -C.sub.4 haloalkylthio;R.sub.3 is hydrogen, halogen or C.sub.1 -C.sub.4 haloalkyl; orR.sub.1 and R.sub.2 taken together are C.sub.1 -C.sub.4 alkylenedioxy or halo-C.sub.1 -C.sub.3 alkylenedioxy; provided that R.sub.1, R.sub.2 and R.sub.3 are not all hydrogen;R.sub.4 is methyl, ethyl, n-propyl, C.sub.3 -C.sub.7 branched alkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.2 -C.sub.4 alkenyl; or cyclopropyl, optionally substituted by up to 4 methyl groups or up to 2 halogens;R.sub.5 is: ##STR2## R.sub.6 is phenyl, benzyl, C.sub.3 -C.sub.4 alkenyl, or C.sub.3 alkynyl; R.sub.7, R.sub.8, R.sub.10 and R.sub.11 are each halogen; andR.sub.
    Type: Grant
    Filed: November 30, 1990
    Date of Patent: February 23, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventors: David B. Kanne, Karl J. Fisher, Michael D. Broadhurst
  • Patent number: 5105017
    Abstract: This invention provides novel benzene derivatives which are leukotriene antagonists, formulations of those derivatives, intermediates for preparing the derivatives, and a method of using those derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.
    Type: Grant
    Filed: July 18, 1983
    Date of Patent: April 14, 1992
    Assignee: Eli Lilly and Company
    Inventor: Robert D. Dillard
  • Patent number: 5098934
    Abstract: Novel .omega.-mercaptopropanamides and their homologs of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen and ##STR2## R.sub.1 ' is selected from the group consisting of alkyl of 1 to 5 carbon atoms and aryl optionally substituted with at least one member of the group consisting of --OH, alkyl and alkoxy of 1 to 5 carbon atoms, --NO.sub.2 and halogen, n is an integer from 1 to 5, R.sub.2 is selected from the group consisting of hydrogen alkyl of 1 to 5 carbon atoms and aryl and aralkyl of 6 to 15 carbon atoms optionally substituted with at least one member of the group consisting of alkyl and alkoxy of 1 to 5 carbon atoms, --OH, halogen and --CF.sub.3, R.sub.3 is selected from the group consisting of a) hydrogen, b) phenyl optionally substituted with at least one member of the group consisting of alkyl and alkoxy of 1 to 5 carbon atoms, --OH, --NO.sub.2, halogen, --CF.sub.
    Type: Grant
    Filed: June 22, 1990
    Date of Patent: March 24, 1992
    Assignee: Roussel Uclaf
    Inventors: Jean-Paul Vevert, Francoise Delevallee, Rogert Deraedt
  • Patent number: 5089623
    Abstract: A series of novel imidate insecticides distinguished by the general formula ##STR1## in which R.sub.1 is an optionally substituted aryl group in which the substituents are halo, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.3 -C.sub.6 cycloalkyl, nitro, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.5 carboalkoxy, C.sub.1 -C.sub.4 alkylthio, cyano, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 haloalkylsulfonyl; C.sub.2 -C.sub.5 alkylcarbonyl, C.sub.2 -C.sub.4 alkyleneoxy, C.sub.1 -C.sub.4 alkylenedioxy, C.sub.1 -C.sub.3 halo-substituted alkylenedioxy, phenyl, mono-substituted phenyl, pyridyloxy, C.sub.2 -C.sub.4 alkylene, C.sub.2 -C.sub.4 alkenyl, and/or amido;R.sub.2 is C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.6 haloalkyl, cyclopropyl, cyclobutyl, mono- or poly- halo- or methyl-substituted cyclopropyl, cyano, C.sub.2 -C.sub.4 alkoxyalkyl, C.sub.2 -C.sub.6 haloalkenyl or C.sub.2 -C.sub.6 alkenyl; andR.sub.
    Type: Grant
    Filed: February 15, 1990
    Date of Patent: February 18, 1992
    Assignee: Imperial Chemical Industries Plc
    Inventor: Karl J. Fisher
  • Patent number: 5045566
    Abstract: A series of novel imidate insecticides distinguished by the general formula ##STR1## in which R.sub.1 is an optionally substituted aryl group in which the substituents are halo, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.3 -C.sub.6 cycloalkyl, nitro, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.5 carboalkoxy, C.sub.1 -C.sub.4 alkylthio, cyano, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.2 -C.sub.4 haloalkylsulfonyl; C.sub.2 -C.sub.5 alkylcarbonyl, C.sub.2 -C.sub.4 alkyleneoxy, C.sub.1 -C.sub.2 perhaloalkyleneoxy; C.sub.1 -C.sub.4 alkylendioxy, C.sub.1 -C.sub.3 halo-substituted alkylenedioxy, phenyl, mono-substituted phenyl, pyridyloxy, C.sub.2 -C.sub.4 alkylene, C.sub.2 -C.sub.4 alkenyl, C.sub.3 -haloalkenoxy; and/or amido;R.sub.2 is C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.6 haloalkyl, cyclopropyl, cyclobutyl, mono- or poly- halo- or methyl-substituted cyclopropyl, cyano, C.sub.2 -C.sub.4 alkoxyalkyl, C.sub.2 -C.sub.6 haloalkenyl or C.sub.2 -C.
    Type: Grant
    Filed: April 27, 1989
    Date of Patent: September 3, 1991
    Assignee: ICI Americas Inc.
    Inventors: Michael D. Broadhurst, Thomas H. Cromartie, Karl J. Fisher, William G. Haag
  • Patent number: 4994488
    Abstract: A series of novel imidate insecticides distinguished by the general formula ##STR1## in which R.sub.1 is an optionally substituted aryl group in which the substituents are halo, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.3 -C.sub.6 cycloalkyl, nitro, C.sub.1 -C.sub.4 haloalkyl, C.sub.2 -C.sub.5 carboalkoxy, C.sub.1 -C.sub.4 alkylthio, cyano, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 haloalkylsulfonyl, C.sub.2 -C.sub.5 alkylcarbonyl, C.sub.2 -C.sub.4 alkyleneoxy, C.sub.1 -C.sub.2 perhaloalkyleneoxy, C.sub.1 -C.sub.4 alkylenedioxy, C.sub.1 -C.sub.3 halo-substituted alkylenedioxy, phenyl, mono-substituted phenyl, pyridyloxy, C.sub.2 -C.sub.4 alkylene, C.sub.2 -C.sub.4 alkenyl, C.sub.3 -haloalkenoxy, and/or amido;R.sub.2 is cyclopropyl or mono- or poly- halo- or methyl-substituted cyclopropyl; andR.sub.
    Type: Grant
    Filed: April 27, 1989
    Date of Patent: February 19, 1991
    Assignee: ICI Americas Inc.
    Inventors: Michael D. Broadhurst, Karl J. Fisher, William G. Haag, Michael R. Leadbetter
  • Patent number: 4939300
    Abstract: Aminic orthoester derivatives of the formulae ##STR1## are effective in stabilizing organic materials against oxidative, thermal and actinic degradation.
    Type: Grant
    Filed: November 16, 1987
    Date of Patent: July 3, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Linda A. Benjamin, Joseph E. Barbiarz, Stephen D. Pastor
  • Patent number: 4891443
    Abstract: N,N'-dicyanocyclopropanecarbamidines useful as triazine intermediates, of the formula II ##STR1## in which M is hydrogen or an equivalent of an alkali or earthalkali ion and processes for their production.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: January 2, 1990
    Assignee: Ciba-Geigy Corporation
    Inventor: Henry Szczepanski
  • Patent number: 4769481
    Abstract: The compounds of the formula I ##STR1## in which R.sub.1 to R.sub.5 denote hydrogen; alkyl, alkoxy, alkylmercapto, alkylsulfinyl, alkylsulfonyl, alkylsulfonyloxy each of which can be halogenated, halogen or nitro, R.sub.6 to R.sub.10 denote hydrogen; alkyl, alkoxy, alkenyloxy, alkylmercapto, alkenylmercapto, alkylsulfonyl or C.sub.3 -hydroxyalkyl each of which can be halogenated, (substituted) benzyloxy, alkoxycarbonyl or NRR', and R.sub.7 and R.sub.8 together can form a (substituted) alkylenedioxy radical,X denotes OR.sub.11 in which R.sub.11 denotes optionally halogenated alkyl, cycloalkyl, alkenyl or alkynyl or optionally halogenated benzyl, or SR.sub.12 in which R.sub.12 denotes alkyl or benzyl each of which can be halogenated, andY denotes oxygen or sulfur, subject to the proviso that, if R.sub.1 and R.sub.5 both denote fluorine and R.sub.2, R.sub.3 and R.sub.4 denote hydrogen, the radicals R.sub.6 to R.sub.10 must not each represent halogenated (C.sub.1 -C.sub.
    Type: Grant
    Filed: February 18, 1987
    Date of Patent: September 6, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Volker Koch, Gerhard Burghardt
  • Patent number: 4690708
    Abstract: A herbicide of the formula: ##STR1## in which: Z is N or CX',W, Y, Y', X, Z' and X' represent H, a halogen atom, NO.sub.2, CN or a polyhalogenoalkyl, alkyl or alkoxy group,R.sup.2 represents H, halogen, substituted alkyl, allyl, propargyl, CN, NR.sup.4 R.sup.5, C(X.sup.2)R.sup.7, C(X.sup.2)X.sup.3 R.sup.8, C(X.sup.2)NR.sup.4 R.sup.5, SO.sub.2 F, SO.sub.2 OR.sup.8, SO.sub.2 NR.sup.4 R.sup.5 or P(X.sup.2)R.sup.9 R.sup.10,R.sup.1 is halogen, X.sup.2 R.sup.3 or NR.sup.4 R.sup.5,R.sup.3 is optionally substituted alkyl or is allyl or propargyl,R.sup.4, R.sup.7 and R.sup.8 represent H, alkyl, cycloalkyl, phenyl, allyl, propargyl or the like,R.sup.5 represents R.sup.4, a cation or OR.sup.6, R.sup.6 being H, a cation or alkyl,X.sup.2 and X.sup.3 are O or S,R.sup.9 and R.sup.10 are H, alkyl, OH, OM or R.sup.1, andM is a cation.
    Type: Grant
    Filed: July 11, 1984
    Date of Patent: September 1, 1987
    Assignee: Rhone-Poulenc Agrochimie
    Inventors: Alain Chene, Guy Borrod