Front Cut Patents (Class 56/271)
  • Patent number: 5808047
    Abstract: A process for the preparation of compounds of the formula: ##STR1## wherein Pg and R are protecting groups and B is a nucleobase. The process uses protected nucleobases to form 2,2'-anhydro nucleosides having the formula ##STR2## which are hydrolyzed to 2'-hydroxy intermediates which are then oxidized to the desired 2'-keto compounds. The compounds and intermediates are useful as antiviral and antitumor agents and as intermediates to 2,2'-anhydro-1-(.beta.-D-arabinofuranosyl)cytosine (anhydro-ara-C) and 1-.beta.-D-arabinofuranosylcytosine (Ara-C).
    Type: Grant
    Filed: October 17, 1996
    Date of Patent: September 15, 1998
    Assignee: Eli Lilly and Company
    Inventor: Douglas P. Kjell
  • Patent number: 3968989
    Abstract: An enclosure structure suitable for use in constructing fixed enclosures, trailers, travel trailers, motor homes, buses, and mobile homes, comprising a plurality of wall panels, top panels, and bottom panels, at least one of the panels having a structural frame formed of elongate frame members welded together, each frame member having a tubular member and a channel-forming member of L-shaped cross-section affixed at one edge to the tubular member and cooperating therewith to define a channel, the frame having an insulating material such as a foam plastic arranged intermediate the frame members and outer walls formed of plywood and sheet metal or panels formed of fiberglass and resin. Adjacent panels disposed substantially at right angles to the channel-containing panel have their edges disposed within the channels and means such as screws affixing the channels to the engaged panels.
    Type: Grant
    Filed: July 18, 1974
    Date of Patent: July 13, 1976
    Inventor: Ronald Schippers