Nitrogen In Acid Moiety Patents (Class 560/12)
  • Patent number: 4428964
    Abstract: There are described novel compounds of the formula I defined herein: ##STR1## which have valuable microbicidal properties. The novel compounds can be used for combating microorganisms harmful to plants, particularly for combating phytopathogenic fungi. The compounds of the formula I thus have a very favorable curative and preventive action for practical requirements for the protection of cultivated plants, without the plants being impaired as a result of undesirable secondary effects. The compounds can be used in practice on their own or in the form of pesticidal compositions.
    Type: Grant
    Filed: August 28, 1980
    Date of Patent: January 31, 1984
    Assignee: Ciba-Geigy Corporation
    Inventors: Adolf Hubele, Peter Riebli, Wolfgang Eckhardt, Walter Kunz
  • Patent number: 4426220
    Abstract: Diphenyl ethers of the formula ##STR1## where Z.sup.1, Z.sup.2 and Z.sup.3 independently of one another are each hyrogen, halogen, nitro, cyano, carboxyl, alkyl of 1 to 4 carbon atoms, or haloalkyl, alkoxy, haloalkoxy, alkylmercapto, haloalkylmercapto, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl or haloalkylsulfonyl where alkyl is in each case of 1 to 4 carbon atoms, Y is hydrogen, halogen, cyano or nitro and Q is --CO--NA--OR.sup.1, where A is hydrogen, alkyl of 1 to 4 carbon atoms, a metal ion or an unsubstituted or substituted ammonium ion and R.sup.1 is carboxyalkyl, alkoxycarbonylalkyl or carbamylalkyl of not more than 10 carbon atoms, herbicides which contain these diphenyl ethers as active ingredients, and methods of controlling undesirable plant growth using these active ingredients.
    Type: Grant
    Filed: November 25, 1981
    Date of Patent: January 17, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Adolf Parg, Gerhard Hamprecht, Bruno Wuerzer
  • Patent number: 4423242
    Abstract: Compounds of the general formula ##STR1## wherein Ph is a phenyl group which is optionally substituted by one or more substituents selected from halo (i.e. fluoro, chloro, bromo or iodo), C.sub.1-4 alkyl, amino, C.sub.1-4 alkylamino, di-C.sub.1-4 alkylamino, nitro, sulphonyl, aminosulphonyl, trihalomethyl, carboxy, C.sub.1-4 alkoxycarbonyl, amido, C.sub.1-4 alkylamido C.sub.1-4 alkoxy, C.sub.2-4 alkenyl, cyano, aminomethyl or methylsulphonyl; R.sup.a and R.sup.b, which may be the same or different, each represents a hydrogen or alkali metal (e.g. sodium or lithium) atom or a C.sub.1-4 (e.g. ethyl) group; m is 0 or 1; Y is a group of formula:--NH--CH.sub.2 --CO--or a group of formula: ##STR2## where R.sup.1 is hydrogen or methyl;R.sup.2 is alkyl of 1 to 3 carbon atoms or is methylthiomethyl; andZ is --OR.sup.3 or --NR.sup.4 R.sup.5 where R.sup.3, R.sup.4 and R.sup.5 are each hydrogen or alkyl of 1 to 4 carbon atoms (i.e. methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, or t-butyl) and R.sup.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: December 27, 1983
    Assignee: The Wellcome Foundation Ltd.
    Inventors: Samuel Wilkinson, George W. Hardy, Roger Wrigglesworth
  • Patent number: 4420632
    Abstract: The present specification provides novel analogs of carbacyclin (CBA.sub.2), 6a-carba-prostacyclin (6a-carba-PGI.sub.2), which have pronounced prostacyclin-like pharmacological activity, e.g., as platelet antiaggregatory agents. Specifically the novel chemical analogs of CBA.sub.2 are those substituted by fluoro (C-5), alkyl (C-9), interphenylene (C-5), and methano (C-6a,9). Further provided are benzindene analogs of CBA.sub.2 and substituted forms thereof, i.e., 9-deoxy-2',9-methano (or 2',9-metheno)-3-oxa-4,5,6-trinor-3,7-(1',3'-interphenylene)-PGF.sub.1 compounds. Also provided are a variety of novel chemical intermediates, e.g., substituted bicyclo[3.3.0]octane intermediates, and chemical process utilizing such intermediates which are useful in the preparation of the novel CBA.sub.2 analogs.
    Type: Grant
    Filed: December 22, 1980
    Date of Patent: December 13, 1983
    Assignee: The Upjohn Company
    Inventor: Paul A. Aristoff
  • Patent number: 4420325
    Abstract: This invention relates to benzylsulfonylureas which are active pre- and post-emergence herbicides.
    Type: Grant
    Filed: April 22, 1982
    Date of Patent: December 13, 1983
    Assignee: E. I. Du Pont de Nemours & Company
    Inventor: Richard F. Sauers
  • Patent number: 4419523
    Abstract: N-(substituted benzenesulfonyl) carbamates as new compositions of matter useful as active herbicidal antidotes to protect against and decrease crop injury when used with a thiocarbamate herbicide when applied in various methods; improved herbicidal compositions and utility of said compositions to protect against and decrease phytotoxic crop injury when employing thiocarbamate herbicides and a two-part herbicide system comprising a first-part of one or more thiocarbamate herbicide and a second part of an effective antidote therefor compound said antidote compounds of the class N-benzene sulfonyl carbamates having the formula ##STR1## wherein X is hydrogen, bromo, chloro, methoxy, trifluoromethyl, and methyl; n is an integer from 1 to 3 inclusive, provided that when X is bromo, trifluoromethyl, or methoxy, n is 1; and R is selected from alkyl, haloalkyl wherein halo is chloro or fluoro, alkenyl, haloalkenyl and wherein halo is chloro, alkynyl, trifluoroacetamidomethyl, dialkylamino cyanoalkylthioalkyl, phosphon
    Type: Grant
    Filed: May 11, 1981
    Date of Patent: December 6, 1983
    Assignee: Stauffer Chemical Company
    Inventors: Ferenc M. Pallos, Edmund J. Gaughan
  • Patent number: 4405358
    Abstract: Aralkylaniline derivatives of the general formula ##STR1## where R is alkoxy, cycloalkoxy, alkenyloxy, alkynyloxy, cyanoalkoxy, haloalkoxy, alkylthio, alkenylthio or alkynylthio or unsubstituted or substituted alkyl, cycloalkyl, alkenyl or alkynyl, Y is hydrogen, alkyl, halogen, alkoxy or haloalkyl, A is unsubstituted or substituted alkylene, Z is hydrogen, alkyl, haloalkyl, alkoxyalkyl, cycloalkyl, aralkyl, aryl, aryloxy, halogen, a C.sub.4 H.sub.4 -chain which is fused to the benzene radical to form an unsubstituted or substituted naphthyl radical, alkoxy, haloalkoxy, alkylthio, thiocyanato, cyano, ##STR2## R' and R" each, independently of one another, being hydrogen, alkyl, alkoxy, alkylthio, cycloalkyl or unsubstituted or substituted phenyl, and n is an integer from 1 to 4, and herbicides containing these compounds.
    Type: Grant
    Filed: May 1, 1981
    Date of Patent: September 20, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Ulrich Schirmer, Wolfgang Rohr, Bruno Wuerzer
  • Patent number: 4398036
    Abstract: An improved process for the preparation of N-monosubstituted carbamates by reacting an aromatic primary amine, urea and a monohydric aliphatic alcohol in the presence of a strongly basic tertiary amine catalyst and optionally an inert solvent.
    Type: Grant
    Filed: May 2, 1980
    Date of Patent: August 9, 1983
    Assignee: Atlantic Richfield Company
    Inventor: John J. McCoy
  • Patent number: 4396627
    Abstract: Compounds having the formula: ##STR1## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, Y and X are as defined hereinbelow, are useful for the reduction of abnormally high blood glucose and lipid levels in the treatment of obesity or hyperglycaemia.
    Type: Grant
    Filed: March 15, 1982
    Date of Patent: August 2, 1983
    Assignee: Beecham Group Limited
    Inventors: Anthony T. Ainsworth, David G. Smith
  • Patent number: 4394383
    Abstract: A novel class of chemical compounds useful as pesticides consists of N-alkoxysulfenylcarbamate esters. The preparation of these compounds, their physical properties, formulations, and use to control both household insects and crop pests are exemplified.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: July 19, 1983
    Assignee: Regents of the University of California
    Inventors: Mitsuyasu Kawata, Noriharu Umetsu, Tetsuo R. Fukuto
  • Patent number: 4393211
    Abstract: A process for the preparation of aromatic sulfohalides by reacting an aqueous solution, containing a hydrogen halide, of an aromatic diazonium halide with sulfur dioxide, wherein(a) the aqueous solution, containing the hydrogen halide, of a diazonium salt which is derived from the corresponding aromatic amine and the halogen of the desired sulfohalide is reacted with sulfur dioxide in the presence of an inert organic solvent which is immiscible or only partially miscible with water,(b) the diazonium salt is decomposed, simultaneously or subsequently, by means of a catalyst for diazonium salt decomposition and(c) the resulting reaction mixture, or the organic phase thereof after removal of the aqueous phase, is treated with an oxidizing agent.
    Type: Grant
    Filed: November 12, 1981
    Date of Patent: July 12, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter Tonne, Hagen Jaedicke
  • Patent number: 4389416
    Abstract: Described are compounds of the formula ##STR1## wherein R is hydrogen, loweralkyl, aminomethyl or halo; R.sub.1 is carboxy, carboxyloweralkyl, aminocarbonyl, hydroxymethyl, anilinomethyl, or aminomethyl; A is oxygen, CH.sub.2, Sulfur or a single bond; X is oxygen, CH.sub.2, sulfur or sulfoxide; and Y is hydrogen, loweralkyl or halo and may be the same or different, and pharmaceutically acceptable salts thereof.The compounds are effective as diuretic agents.
    Type: Grant
    Filed: October 9, 1981
    Date of Patent: June 21, 1983
    Assignee: Abbott Laboratories
    Inventor: Jacob J. Plattner
  • Patent number: 4388475
    Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: June 14, 1983
    Assignee: Merck & Co., Inc.
    Inventor: Raymond A. Firestone
  • Patent number: 4386954
    Abstract: This invention is directed to diphenyl ethers having in the 3' position a radical of the formula: ##STR1## The products are prepared by reacting a 3'-halocarbonyl compound with an appropriately substituted oxime. These compounds and their agronomically acceptable salts and compositions containing these compounds as active ingredients are selective herbicides.
    Type: Grant
    Filed: August 17, 1981
    Date of Patent: June 7, 1983
    Assignee: Rohm and Haas Company
    Inventors: John W. Ashmore, Ted T. Fujimoto
  • Patent number: 4381403
    Abstract: A process for the preparation of N-monosubstituted carbamic acid esters by reacting an unsubstituted carbamic acid ester and an aromatic primary amine at a suitable pressure and reaction temperature in the presence of a monohydric aliphatic alcohol and preferably in the presence of a strongly basic tertiary amine as catalyst. Optionally an inert co-solvent in addition to the alcohol may be employed.
    Type: Grant
    Filed: March 31, 1980
    Date of Patent: April 26, 1983
    Assignee: Atlantic Richfield Company
    Inventors: Samuel J. Falcone, John J. McCoy
  • Patent number: 4372972
    Abstract: This invention relates to N-substituted alkynyl anilines, methods for their preparation and their use as systemic eradicant phytopathogenic fungicides which are useful in controlling Oomycetes.
    Type: Grant
    Filed: September 14, 1979
    Date of Patent: February 8, 1983
    Assignee: Rohm and Haas Company
    Inventor: Hak-Foon Chan
  • Patent number: 4371547
    Abstract: 2-Benzylideneglutaraldehydes of the formula ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 independently are hydrogen or a substituent selected from the group consisting of halo, lower-alkyl, phenyl, carboxy, lower-alkoxycarbonyl, phenoxycarbonyl, aminocarbonyl, hydroxysulfonyl, nitro, cyano, hydroxy, lower-alkoxy and phenoxy, a method of use thereof as disinfectants, disinfectant compositions comprising them, and 2,6-dialkoxy-3-(.alpha.-alkoxybenzyl)tetrahydropyrans of the formula ##STR2## where R.sup.1, R.sup.2 and R.sup.3 are as defined above and R.sup.4 and R.sup.5 independently are alkyl of one to four carbon atoms, which are intermediates for their preparation are disclosed.
    Type: Grant
    Filed: August 21, 1981
    Date of Patent: February 1, 1983
    Assignee: Sterling Drug Inc.
    Inventors: Wolfgang Munzenmaier, Heinz Eggensperger, Helmut H. Ehlers, Wolfgang Beilfuss, Lothar Bucklers, Hans-Peter Harke
  • Patent number: 4364867
    Abstract: The present invention relates to a novel veratramide, N-(1-methyl-2-pyrroinyl-methyl)-2,3-dimethoxy-5-methylsulphamoyl benzamide, its pharmacologically acceptable acid addition salts, its quaternary ammonium salts, its oxides and its levorotatory and dextrorotatory isomers and their use in the treatment of disorders of the lower urinary apparatus.
    Type: Grant
    Filed: December 11, 1980
    Date of Patent: December 21, 1982
    Assignee: Societe d'Etudes Scientifiques et Industrielles de l'Ile de France
    Inventors: Michel Thominet, Jacques Perrot
  • Patent number: 4358308
    Abstract: The 4-perfluoroacetyl-, 4-perfluoromethylthio-, 4-perfluoromethylsulfinyl-, and 4-perfluoromethylsulfonyl-4'-nitrodiphenyl ethers comprise a class of compounds that are highly effective herbicides.
    Type: Grant
    Filed: October 19, 1981
    Date of Patent: November 9, 1982
    Assignee: Rohm and Haas Company
    Inventor: Colin Swithenbank
  • Patent number: 4353834
    Abstract: Biodegradable non-ionic surface-active agents containing carbonate groups can be prepared by reacting hydrophilic polyoxyalkylene glycols derived from the same or different alkylene oxides with hydrophobic amides or sulfonamides. The compositions of the invention contain both hydrophilic and hydrophobic groups in the molecule making them suitable for use as surface-active agents.
    Type: Grant
    Filed: March 13, 1981
    Date of Patent: October 12, 1982
    Assignee: BASF Wyandotte Corporation
    Inventor: William K. Langdon
  • Patent number: 4349471
    Abstract: A process for the simultaneous preparation of an aromatic sulphonic acid halide and an aromatic carboxylic acid halide or the corresponding carboxylic acid is disclosed wherein an aromatic sulphonic acid or acid anhydride is reacted with an aromatic trihalogenomethyl compound in the presence of a Bronsted acid or Lewis acid at a temperature of 20.degree. to 300.degree. C., if appropriate in the presence of a solvent. Generally, at least half an equivalent of aromatic trihalogenomethyl compound is employed per equivalent of sulphonic acid.
    Type: Grant
    Filed: January 22, 1981
    Date of Patent: September 14, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Heinz U. Blank, Erich Wolters, Norbert Langenfeld
  • Patent number: 4349378
    Abstract: Sulphonanilides of formula ##STR1## and salts thereof, wherein R.sup.1 represents alkyl or certain other groups;R represents alkylene or alkenylene;A represents --COR.sup.12 or a carbonyl derivative or addition compound thereof, where R.sup.12 represents hydrogen, alkyl or certain other groups; andR.sup.2 -R.sup.6 represent hydrogen, alkyl, halogen or certain other groups;are pesticides and plant growth regulants, especially herbicides and fungicides.
    Type: Grant
    Filed: December 14, 1978
    Date of Patent: September 14, 1982
    Assignee: FBC Limited
    Inventors: Geoffrey R. Cliff, Russell G. Hunt, Albert Percival
  • Patent number: 4348219
    Abstract: Novel 2-[[(heterocyclic)-aminocarbonyl]aminosulfonyl]benzeneacetic acid derivatives, such as 2-[[(4,6-dimethoxypyrimidin-2-yl)-aminocarbonyl]aminosulfonyl]benzeneaceti c acid, methyl ester, are useful as plant growth regulants and herbicides.
    Type: Grant
    Filed: April 29, 1981
    Date of Patent: September 7, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: George Levitt
  • Patent number: 4348406
    Abstract: Compounds of the formula: ##STR1## and their pharmaceutically acceptable acid addition salts, useful as anthelmintics are disclosed.
    Type: Grant
    Filed: October 20, 1980
    Date of Patent: September 7, 1982
    Assignee: Schering Corporation
    Inventor: M. Mehdi Nafissi-Varchei
  • Patent number: 4348220
    Abstract: This invention relates to a novel class of N-(heterocyclicaminocarbonyl)-o-alkoxymethylbenzene sulfonamide herbicides.
    Type: Grant
    Filed: May 27, 1981
    Date of Patent: September 7, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Gregory W. Schwing
  • Patent number: 4339592
    Abstract: A urethane is produced by reacting an organic nitro compound with carbon monoxide and an organic compound containing at least one hydroxyl group in the presence of a catalyst and a co-catalyst. This reaction is conducted in the liquid phase at elevated temperature and pressure. The catalyst employed is an element and/or compound of an element from the group of noble metals of the 8th Secondary Group of the Periodic Table. The co-catalyst used is formed from (1) a component taken from the group consisting of iron oxychloride, a mixture of iron compounds containing iron oxychloride and oxide-chloride combinations and (2) metallic iron or an iron alloy in finely divided or high surface form. The oxides which may be used in the oxide-chloride combinations of co-catalyst component (1) are the oxides and/or oxide hydrates of tetravalent tin, trivalent chromium, hexavalent molybdenum, hexavalent tungsten, pentavalent vanadium, divalent iron and trivalent iron.
    Type: Grant
    Filed: February 26, 1981
    Date of Patent: July 13, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Robert Becker, Christian Rasp, Gunter Stammann, Johann Grolig
  • Patent number: 4338258
    Abstract: Fluorescent dyestuffs of the general formula ##STR1## wherein R and R.sup.1 independently of one another represent hydrogen, a salt-forming cation, an alkyl radical with 1 to 16 C atoms or an aryl or aralkyl radical which is optionally substituted by non-chromophoric groups,R.sup.2 to R.sup.5 independently of one another represent hydrogen, alkyl, trifluoromethyl, alkoxy, aralkoxy, alkenoxy, aryloxy, halogen or a carboxyl, cyano, alkyl sulphone, aryl sulphone, aralkyl sulphone, carboxamide, sulphonamide or carboxylic acid ester group,o, p, q and s independently of one another represent 1 or 2 andm and n independently of one another denote 0, 1 or 2, it being possible for the sum of m and n to be 2 to 4,processes for their preparation and their use as laser dyestuffs.
    Type: Grant
    Filed: September 8, 1980
    Date of Patent: July 6, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Brinkwerth, Wolfgang Huffer, Roderich Raue, Rudolf Schieder, Helmut Telle
  • Patent number: 4338457
    Abstract: The present invention relates to novel compositions of matter and novel processes for preparing these compositions of matter. Moreover, there are provided novel methods by which certain of these novel compositions of matter are employed for pharmacologically useful purposes.
    Type: Grant
    Filed: February 28, 1980
    Date of Patent: July 6, 1982
    Assignee: The Upjohn Company
    Inventor: Paul A. Aristoff
  • Patent number: 4338333
    Abstract: The compounds of formula (II): ##STR1## in which R.sub.1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R.sub.2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R.sub.3 is a hydrogen, chlorine or bromine atom or a hydroxyl group, R.sub.4 is a hydrogen atom or a methyl group; R.sub.5 is a hydrogen atom or a methyl group; R.sub.6 is a hydrogen, fluorine or chlorine atom or a methyl, methoxyl or hydroxy group; X is an oxygen atom or a bond; Y is an alkylene group of up to 6 carbon atoms or a bond; and Z is an alkylene, alkenylene or alkynylene group of up to 10 carbon atoms, have been found to possess anti-obesity and/or anti-hyperglycaemic activity.
    Type: Grant
    Filed: June 9, 1980
    Date of Patent: July 6, 1982
    Assignee: Beecham Group Limited
    Inventors: Anthony T. Ainsworth, David G. Smith
  • Patent number: 4335246
    Abstract: Substituted arylamine dye intermediates and their preparation are disclosed.
    Type: Grant
    Filed: September 24, 1979
    Date of Patent: June 15, 1982
    Assignee: Aziende Colori Nazionali Affini ACNA S.p.A.
    Inventors: Francesco De Feo, Giovanni Burei, Roberto Cipolli
  • Patent number: 4331680
    Abstract: Novel compounds are described which are substituted benzophenone hydrazones. They have pesticidal activity, especially against insects and acarids, and pesticidal compositions and methods are described. Methods of making the compounds, and novel intermediates, are also described.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: May 25, 1982
    Assignee: The Boots Company
    Inventors: David P. Giles, John C. Kerry, Antonin Kozlik, Bryan H. Palmer, Stephen W. Shutler, Robert J. Willis
  • Patent number: 4321368
    Abstract: Ethylene is polymerized in the vapor phase in a stirred bed reactor. The reactor employed is vertically aligned and has a centrally positioned cored draft tube therein. An auger circulates polymer solids through the draft tube while coolant is circulated there through to remove the heat of polymerization.
    Type: Grant
    Filed: May 1, 1980
    Date of Patent: March 23, 1982
    Assignee: Mallinckrodt, Inc.
    Inventor: George B. Hoey
  • Patent number: 4309443
    Abstract: A compound of the formula (I): ##STR1## or a pharmaceutically acceptable ester, amide or salt thereof wherein R.sub.1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R.sub.2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R.sub.3 is a hydrogen, chlorine or bromine atom or a hydroxyl group; R.sub.4 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R.sub.5 is a hydrogen atom or a methyl group; R.sub.6 is a hydrogen atom or a methyl group; R.sub.7 is a hydrogen atom or a methyl or ethyl group; R.sub.
    Type: Grant
    Filed: September 3, 1980
    Date of Patent: January 5, 1982
    Assignee: Beecham Group Limited
    Inventors: David G. Smith, Anthony T. Ainsworth
  • Patent number: 4309559
    Abstract: Sulphonanilides of formula ##STR1## and salts thereof, wherein R.sup.1 represents alkyl or certain other groups;R represents alkylene or alkenylene;A represents --COOH, --COO alkyl, --CSSH, CN or certain related groups; orR-A represents a group of formula ##STR2## where R.sup.14 represents hydrogen, alkyl or aryl, B represents oxygen or ##STR3## R.sup.15 represents hydrogen or alkyl, and n represents 0, 1 or 2; and R.sup.2 -R.sup.6 represent hydrogen; alkyl, halogen or certain other groups,are pesticides and plant growth regulants, especially herbicides and fungicides.
    Type: Grant
    Filed: December 14, 1978
    Date of Patent: January 5, 1982
    Assignee: FBC Limited
    Inventor: Geoffrey R. Cliff
  • Patent number: 4309425
    Abstract: Sulfonamides, such as N-[N-(2-chloro-5-(trifluoromethyl)phenyl]-N-[2,4-dinitro-6-(trifluoromethy l)phenyl]aminothio]-N,4-dimethylbenzenesulfonamide, are useful for control of arthropod pests of plants and animals and fungus disease of plants.
    Type: Grant
    Filed: April 11, 1980
    Date of Patent: January 5, 1982
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Jiin-Duey Cheng
  • Patent number: 4305884
    Abstract: This invention relates to novel o-carbonylbenzenesulfonyl isocyanates and their use as intermediates for the preparation of sulfonylureas which are known to be active herbicides.
    Type: Grant
    Filed: July 23, 1980
    Date of Patent: December 15, 1981
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: George Levitt
  • Patent number: 4304728
    Abstract: Compounds are described of the formula ##STR1## in which R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano, 5-tetrazolyl or R.sup.6, where R.sup.5 is hydrogen or C.sub.1-8 alkyl and R.sup.6 is phenyl or naphthyl, the phenyl or naphthyl group being optionally substituted by one or more group selected from halogen, C.sub.1-6 alkyl, C.sub.1-4 alkoxy, hydroxy, benzyloxy, nitro, trifluoromethyl, carboxyl, C.sub.1-4 alkylsulphinyl, C.sub.1-4 alkylsulphonyl, N(R.sup.5).sub.2, NHCOR.sup.5 and SR.sup.5 ; R.sup.2 is R.sup.6 or --CH.dbd.CH--R.sup.6 when R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano or 5-tetrazolyl, or R.sup.2 is --CH.dbd.CH--R.sup.6 when R.sup.1 is R.sup.6 ; R.sup.3 is hydrogen, C.sub.1-6 alkyl, halogen, hydroxy or --OCH.sub.2 R.sup.6 ; and R.sup.4 is hydrogen, C.sub.1-6 alkyl or halogen; and salts thereof. The compounds have pharmaceutical properties and in particular are useful in the treatment of immediate hypersensitivity conditions such as asthma.
    Type: Grant
    Filed: March 27, 1980
    Date of Patent: December 8, 1981
    Assignee: Lilly Industries Limited
    Inventors: Barry P. Clark, William J. Ross, Alec Todd
  • Patent number: 4300942
    Abstract: This disclosure relates to N-(substituted carbonyl) triester derivatives of N-phosphinylmethylglycine wherein a substituted thiocarbonyl, RS(CO)--, a substituted sulfinylcarbonyl, ##STR1## or a substituted sulfonyl carbonyl, ##STR2## group is bonded to the nitrogen atom, to herbicidal compositions containing the same and to the herbicidal use thereof.
    Type: Grant
    Filed: June 25, 1980
    Date of Patent: November 17, 1981
    Assignee: Monsanto Company
    Inventor: Robert J. Kaufman
  • Patent number: 4293701
    Abstract: N-(Substituted benzenesulfonyl) carbamates as new compositions of matter useful as active herbicidal antidotes to protect against and decrease crop injury when used with a thiocarbamate herbicide when applied in various methods; improved herbicidal compositions and utility of said compositions to protect against and decrease phytotoxic crop injury when employing thiocarbamate herbicides and a two-part herbicide system comprising a first-part of one or more thiocarbamate herbicide and a second part of an effective antidote therefor compound said antidote compounds of the class N-benzene sulfonyl carbamates having the formula ##STR1## wherein X is hydrogen, bromo, chloro, methoxy, trifluoromethyl, and methyl; n is an integer from 1 to 3 inclusive, provided that when X is bromo, trifluoromethyl, or methoxy, n is 1; and R is selected from alkyl, haloalkyl wherein halo is chloro or fluoro, alkenyl, haloalkenyl and wherein halo is chloro, alkynyl, trifluoroacetamidomethyl, dialkylamino cyanoalkylthioalkyl, phosphon
    Type: Grant
    Filed: December 31, 1979
    Date of Patent: October 6, 1981
    Assignee: Stauffer Chemical Company
    Inventors: Ferenc M. Pallos, Edmund J. Gaughan
  • Patent number: 4291176
    Abstract: Insecticidally active vinyl-cyclopropane carboxylic acid esters of the formula ##STR1## are prepared by reacting ##STR2## in which R.sup.12 is a radical selected from the group consisting of ##STR3## with an alcoholate of the formulaM--O--R.sup.8.Various processes for making the intermediates are also described. Many of the intermediates and end products are new.
    Type: Grant
    Filed: August 24, 1977
    Date of Patent: September 22, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Georg Heine, Willy Hartmann
  • Patent number: 4287083
    Abstract: Acyloin urethans can be employed to effect photopolymerization of free radical-polymerizable compositions in inert and oxygen-containing atmospheres.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: September 1, 1981
    Assignee: Lord Corporation
    Inventors: John R. McDowell, Dennis D. Howard, Vincent J. Pascarella
  • Patent number: 4283414
    Abstract: The invention concerns novel pesticidal esters of the pyrethrin or pyrethroid type in which the methylene group bonded to the ester carbonyl and/or ester oxygen bears a fluorine substituent. The compounds of the invention are active against insect pests including flies, moths, aphids and beetles and acarina pests including ticks.
    Type: Grant
    Filed: June 8, 1979
    Date of Patent: August 11, 1981
    Assignee: ICI Australia Limited
    Inventors: Donald W. G. Harney, Peter G. Lehman, Joseph C. Rundle
  • Patent number: 4283538
    Abstract: In one embodiment, the present invention is concerned with novel triarylmethane compounds possessing in their triaryl structure a 4'-oxo-1'-naphthylidene (or a 4'-oxo-1'-phenylidene) moiety and a phenyl moiety substituted in the ortho-position to the central carbon atom with the group ##STR1## wherein R is an alkyl group or a phenyl group, unsubstituted or substituted with a solubilizing group; R' is selected from ##STR2## wherein R" is methyl, unsubstituted or substituted with one or two halo groups or substituted with a phenyl, alkoxy or phenoxy group and ##STR3## wherein Y is an electron-withdrawing group; and R and R' taken with said ##STR4## represents ##STR5## In another embodiment the present invention is concerned with a method of synthesizing the aforementioned compounds by reacting, e.g., a 2-R'-3-(4'-hydroxy-1'-phenyl/naphthyl)-3-(phenyl/naphthyl)-2,3-dihydrobenz [d]isothiazole-1,1-dioxide with an alkylation reagent in the presence of base.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: August 11, 1981
    Assignee: Polaroid Corporation
    Inventor: James W. Foley
  • Patent number: 4279637
    Abstract: This invention discloses chemical compounds of the formula ##STR1## wherein X and Z are each independently selected from the group consisting of halogen, haloalkyl, nitro, cyano, alkyl, alkoxy and alkylthio; m and n are each independently integers of from 0 to 4; Y is selected from the group consisting of oxygen, sulfur, methylene, sulfonyl and sulfinyl; and R is selected from the group consisting of hydrogen, alkyl and alkoxy. The compounds of the above description are useful as herbicides.
    Type: Grant
    Filed: May 29, 1980
    Date of Patent: July 21, 1981
    Assignee: Velsicol Chemical Corporation
    Inventor: Frank Wu
  • Patent number: 4276436
    Abstract: The present invention provides novel 19-keto-PG sulfonylamides, which are useful for a variety of pharmacological purposes, e.g., antiasthmatic indications.
    Type: Grant
    Filed: March 20, 1980
    Date of Patent: June 30, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Patent number: 4272546
    Abstract: This disclosure describes esters of 4-(monoalkylamino)benzoic acids with hydroxyalkanoic acids and derivatives, phenols, or 3-pyridinols useful as hypolipidemic and antiatherosclerotic agents.
    Type: Grant
    Filed: October 22, 1979
    Date of Patent: June 9, 1981
    Assignee: American Cyanamid Company
    Inventor: Robert G. Shepherd
  • Patent number: 4267352
    Abstract: The present invention provides novel 19-hydroxy-19-methyl-6-oxo-PGF.sub.1 sulfonylamides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: May 12, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Patent number: 4266074
    Abstract: Substituted acetate compounds represented by the formula ##STR1## which are useful as pesticides and pesticidal composition containing the substituted acetate compounds as active ingredients, as well as processes for preparing the compounds and the compositions are disclosed.
    Type: Grant
    Filed: July 16, 1975
    Date of Patent: May 5, 1981
    Assignee: Sumitomo Chemical Company Limited
    Inventors: Keimei Fujimoto, Nobuo Ohno, Yoshitoshi Okuno, Toshio Mizutani, Isao Ohno, Masachika Hirano, Nobushige Itaya, Takashi Matsuo
  • Patent number: 4258058
    Abstract: Phenoxyalkylcarboxylic acid compounds of the formula ##STR1## wherein R is hydrogen or lower alkylR.sub.1 is alkyl or aryl, aralkyl or aralkenyl radical, the aryl moiety of which can be substituted one or more times by halogen, hydroxyl, trifluoromethyl or lower alkyl, alkoxy or acylR.sub.2 and R.sub.3 are individually selected from hydrogen or lower alkyl, andn is 0, 1, 2 or 3and the physiologically acceptable salts, esters and amides thereof; are outstandingly effective in inhibiting thrombocyte aggregation.
    Type: Grant
    Filed: February 26, 1979
    Date of Patent: March 24, 1981
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ernst-Christian Witte, Hans P. Wolff, Max Thiel, Karlheinz Stegmeier, Egon Roesch
  • Patent number: 4252978
    Abstract: The present invention provides novel 19-hydroxy-6-oxo-PGF.sub.1 sulfonylamides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: February 24, 1981
    Assignee: The Upjohn Company
    Inventor: John C. Sih