With Preservative Patents (Class 560/2)
-
Patent number: 9434807Abstract: Carbodiimide containing compositions include diilsocyenates, polyols, and liquid carbodiimide of the formula where R1, R2, R4 and R6 are each independently C3-C6-alkyl, and R3 and R5 are each independently C1-C3-alkyl.Type: GrantFiled: March 22, 2013Date of Patent: September 6, 2016Assignee: Rhein Chemie Rheinau GmbHInventors: Wilhelm Laufer, Armin Eckert, Martina Hauck
-
Patent number: 8921451Abstract: Use of aziridines for stabilizing iodine-containing compounds, especially biocides.Type: GrantFiled: March 25, 2010Date of Patent: December 30, 2014Assignee: LANXESS Deutschland GmbHInventors: Andreas Böttcher, Bernd Koop, Peter Spetmann
-
Publication number: 20140323754Abstract: The present invention relates to novel biobased carbodiimides, a process for production thereof and use thereof.Type: ApplicationFiled: May 22, 2014Publication date: October 30, 2014Applicant: RHEIN CHEMIE RHEINAU GmbHInventors: Wilhelm Laufer, Armin Eckert, Franco Orsini, Robert Eiben
-
Patent number: 8278332Abstract: The photostabilizing electronic excited state energy—particularly singlet state energy from retinoid compounds—has been found to be readily transferred to (accepted by) ?-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinafter “alkoxycrylenes”) on one of the phenyl rings having the formula (I): wherein one of R1 and R2 is a straight or branched chain C1-C30 alkoxy radical, preferably C1-C8, more preferably methoxy, and the non-alkoxy radical R1 or R2 is hydrogen; and R3 is a straight or branched chain C1-C30 alkyl radical, preferably C2-C20. The alkoxycrylene compounds of formula (I) significantly increase the photostability of retinoid compounds in a composition by at least 3-fold.Type: GrantFiled: October 27, 2011Date of Patent: October 2, 2012Assignee: Hallstar Innovations Corp.Inventors: Craig A. Bonda, Anna Pavlovic, Jean Zhang
-
Patent number: 8263051Abstract: The photostabilizing electronic excited state energy—particularly singlet state energy from resveratrol compounds—has been found to be readily transferred to (accepted by) ?-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinafter “alkoxycrylenes”) on one of the phenyl rings having the formula (I): wherein one of R1 and R2 is a straight or branched chain C1-C30 alkoxy radical, preferably C1-C8, more preferably methoxy, and the non-alkoxy radical R1 or R2 is hydrogen; and R3 is a straight or branched chain C1-C30 alkyl radical, preferably C2-C20. The alkoxycrylene compounds of formula (I) significantly increase the photostability of resveratrol compounds in a composition by at least 3-fold and as much as 10-fold or greater. The ability of the alkoxycrylene compounds to stabilize the resveratrol compound is concentration dependent, with the amount of resveratrol photostabilization increasing with the concentration of the alkoxycrylene compound.Type: GrantFiled: April 5, 2011Date of Patent: September 11, 2012Assignee: Hallstar Innovations Corp.Inventors: Craig A. Bonda, Anna Pavlovic, Jean Zhang
-
Publication number: 20120208918Abstract: Use of aziridines for stabilizing iodine-containing compounds, especially biocides.Type: ApplicationFiled: March 25, 2010Publication date: August 16, 2012Applicant: LANXESS DEUTSCHLAND GMBHInventors: Andreas Böttcher, Bernd Koop, Peter Spetmann
-
Publication number: 20120101295Abstract: An olefinically unsaturated monomer is stabilized by a retarder-containing composition which comprises a solvent and a quinone methide as a retarder.Type: ApplicationFiled: January 3, 2012Publication date: April 26, 2012Applicant: EVONIK DEGUSSA GmbHInventors: Stefanie Weyler, Phillip James, Oliver Erpeldinger, Manfred Neumann, Frank Kraushaar
-
Publication number: 20110306783Abstract: The present invention relates to a composition which comprises at least one hydroxyalkyl(meth)acrylate and has been stabilized for a purification, which comprises hydroquinone monomethyl ether and 4-hydroxy-2,2,6,6-tetramethylpiperidine N-oxyl. The present invention additionally describes processes for purifying and for preparing hydroxyalkyl(meth)acrylates. A further aspect of the present invention is a composition which is obtainable by the processes mentioned.Type: ApplicationFiled: February 25, 2010Publication date: December 15, 2011Applicant: Evonik Roehm GmbHInventors: Dirk Broell, Benedikt Laux, Christian Maul, Thorben Schuetz, Bardo Schmitt, Volker Schleep, Claus Zimmer
-
Publication number: 20110295034Abstract: An eye drop composition in which the degradation of isopropyl unoprostone in an eye drop is prevented by adding trometamol to the eye drop containing isopropyl unoprostone.Type: ApplicationFiled: July 28, 2011Publication date: December 1, 2011Applicant: SANTEN PHARMACEUTICAL CO., LTD.Inventors: Hiroyuki Asada, Akio Kimura
-
Publication number: 20110251242Abstract: The photostabilizing electronic excited state energy—particularly singlet state energy from resveratrol compounds—has been found to be readily transferred to (accepted by) ?-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinafter “alkoxycrylenes”) on one of the phenyl rings having the formula (I): wherein one of R1 and R2 is a straight or branched chain C1-C30 alkoxy radical, preferably C1-C8, more preferably methoxy, and the non-alkoxy radical R1 or R2 is hydrogen; and R3 is a straight or branched chain C1-C30 alkyl radical, preferably C2-C20. The alkoxycrylene compounds of formula (I) significantly increase the photostability of resveratrol compounds in a composition by at least 3-fold and as much as 10-fold or greater. The ability of the alkoxycrylene compounds to stabilize the resveratrol compound is concentration dependent, with the amount of resveratrol photostabilization increasing with the concentration of the alkoxycrylene compound.Type: ApplicationFiled: April 5, 2011Publication date: October 13, 2011Applicant: HALLSTAR INNOVATIONS CORP.Inventors: Craig A. Bonda, Anna Pavlovic, Jean Zhang
-
Publication number: 20110137066Abstract: It is an object of the invention to provide a process of inhibiting polymerization of isocyanate group-containing, ethylenically unsaturated carboxylate compounds, and a process for producing isocyanate group-containing, ethylenically unsaturated carboxylate compounds which involves the polymerization inhibition process. The process of inhibiting polymerization of isocyanate group-containing, ethylenically unsaturated carboxylate compounds of the invention includes controlling the oxygen gas (O2) concentration in a liquid phase containing an isocyanate group-containing, ethylenically unsaturated carboxylate compound to not less than 0.5 mg/L. In a preferred embodiment, a gas containing oxygen gas (O2) is introduced to the liquid phase. In another preferred embodiment, the oxygen gas (O2) concentration in the liquid phase is measured with an electrode that is immersed in the liquid phase.Type: ApplicationFiled: August 6, 2009Publication date: June 9, 2011Applicant: Showa Denko K.K.Inventors: Norihito Nishimura, Shinichi Yorozuya
-
Publication number: 20100130606Abstract: The present application relates to a pharmaceutical granulate comprising Fesoterodine or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable stabilizer, which can be selected from the group consisting of sorbitol, xylitol, polydextrose, isomalt, dextrose, and combinations thereof, and is preferably a sugar alcohol selected from the group consisting of xylitol and sorbitol. The granulate is suitable for incorporation into pharmaceutical compositions comprising a gel matrix formed by at least one type of hydroxypropyl methylcellulose into which the Fesoterodine is embedded and, optionally, further excipients. In certain embodiments, the granulate is formed by a process of wet granulation.Type: ApplicationFiled: January 22, 2010Publication date: May 27, 2010Applicant: SCHWARZ PHARMA AGInventors: Hans-Jürgen MIKA, Christoph ARTH, Michael KOMENDA, Fatima BICANE, Kerstin PAULUS, Meike IRNGARTINGER, Hans LINDNER
-
Patent number: 7151155Abstract: Disclosed are copolymers of cyclic esters, e.g., caprolactone, and cyclic formals of substituted or unsubstituted diols, e.g., 1,3-dioxepane. The copolymers can provide a low melting temperature rendering them liquids at room temperature. Elastomeric polyurethanes prepared from such copolymers can exhibit a low Tg transition and good resistance to hydrolysis and oxidation. The copolymers are particularly useful for elastomers, coatings, adhesives, inks or binders requiring low temperature flexibility and good resistance to hydrolysis and oxidation.Type: GrantFiled: April 17, 2001Date of Patent: December 19, 2006Assignee: Union Carbide Chemicals & Plastics Technology CorporationInventors: Thomas A. Upshaw, Angelo Mellozzi
-
Patent number: 7091242Abstract: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions containing them as well as their use for the production of pharmaceutical compositions for the treatment of inflammatory diseases.Type: GrantFiled: October 8, 2001Date of Patent: August 15, 2006Assignee: Bayer AktiengesellschaftInventors: Thomas Rölle, Thomas Lehmann, Markus Albers, Gerhard Hessler, Gerhard Müller, Rüdiger Fischer, Masaomi Tajimi, Karl Ziegelbauer, Kevin Bacon, Haruki Hasegawa, Hiromi Okigami
-
Patent number: 6992225Abstract: The invention concerns a heat stabilizer of organic peroxides characterized in that it is an N-hetrocyclic compound which contains at least one nitroxyl radical with the N atom of the nitroxyl radical forming part of the ring. The invention also concerns a storage-stable and heat-stable organic peroxide composition containing an N-hetrocyclic compound which contains at least one nitroxyl radical with the N atom of the nitroxyl radical forming part of the ring, the method for preparing the same and uses thereof for modifying polymers.Type: GrantFiled: April 30, 2002Date of Patent: January 31, 2006Assignee: ArkemaInventors: Sandra Grimaldi, Olivier Guerret, Jean-Luc Couturier, Fabien Debaud
-
Patent number: 6537467Abstract: The present invention relates to free radical captors, especially to radical polymerization inhibitors or retarders which, characteristically, are immobilized on a solid support. The present invention also relates to a method of preparing said immobilized captors, and to a method of stabilizing, at least temporarily, molecules or mixtures of molecules which makes use of said immobilized captors.Type: GrantFiled: April 28, 1999Date of Patent: March 25, 2003Assignee: Corning IncorporatedInventor: Marc Moroni
-
Patent number: 6291719Abstract: The present invention relates to a method of catalyzing etherification, esterification, hydration, ether cleavage, isomerization alkylation, or other reactions which are catalyzable with an acid or molecular sieve catalyst. Said reactions are conducted using a novel, dual functional catalyst prepared with active components and a small amount of binder, wherein said dual functional catalyst comprises cylindrical pellets which are molded such that a cross-section or each pellet has a window lattice shape with external teeth, or a star shape with inner spokes.Type: GrantFiled: August 29, 2000Date of Patent: September 18, 2001Assignees: China Petro-Chemical Corporation, Qilu Petro-Chemical Corporation SinopecInventors: Buliang Gao, Jinyong Zhang, Jinshan Wang, Xingren Hao, Zaiqun Yu, Wei Wang
-
Patent number: 5750678Abstract: The invention relates to a water-soluble, haemolytically inactive dextran fatty carboxylate with amphiphilic properties made from a dextran with an average molecular weight of 5,000 to 100,000 and a C.sub.10 to C.sub.14 fatty acid, preferably a C.sub.12 fatty acid, wherein the average degree of substitution is between 0.005 and 0.15 and is adjusted, depending on the average molecular weight of the dextran fatty carboxylate and the chain-length of the fatty acid used, in such a way that the dextran fatty carboxylate is soluble in water at room temperature, a process for its preparation and pharmaceutical or cosmetic preparations which contain it as solubilizer.Type: GrantFiled: August 30, 1996Date of Patent: May 12, 1998Assignee: Kurt H. BauerInventors: Kurt H. Bauer, Thomas Reinhart
-
Patent number: 5670692Abstract: Ethylenically unsaturated monomers are protected from premature polymerization during manufacture and storage by the incorporation therein of an effective stabilizing amount of a 7-substituted quinone methide compound.Type: GrantFiled: August 27, 1996Date of Patent: September 23, 1997Assignee: Ciba-Geigy CorporationInventors: Peter Nesvadba, Samuel Evans, Matthew E. Gande, Volker H. von Ahn, Roland A. E. Winter
-
Patent number: 5621136Abstract: A method of stabilizing an aqueous solution of an acid copolymer of maleic acid and a C.sub.1 -C.sub.5 alkyl vinyl ether against degradation in viscosity or molecular weight upon storage for an extended period of time in aqueous solution at ambient conditions, with a single stabilizing agent, which comprises forming the acid copolymer, preferably directly from a slurry of corresponding anhydride in an organic solvent by hydrolysis in water, and adding superoxide dismutase as the single stabilizing agent to the solution either before or after hydrolysis.Type: GrantFiled: October 13, 1995Date of Patent: April 15, 1997Assignee: ISP Investments Inc.Inventors: Chi-San Wu, James Curry, James P. Cullen, John S. McEwan
-
Patent number: 5614648Abstract: A method of producing an antioxidant containing derivatives of an organic compound, and in particular, an antioxidant glyceride derivative, comprises reacting a first compound with a second medium. By this reaction, a product is formed whereby an active component of the first compound, e.g., an antioxidant moiety, is covalently incorporated into the second medium.The second medium comprises glyceride derivatives, silicones, fluorocarbons and alkoxylates containing reactive groups such as hydroxy, amino, carboxyl, ester, or amides.Type: GrantFiled: January 10, 1995Date of Patent: March 25, 1997Inventors: George H. Greene, Robert Miller, James L. Williams, James C. Phillips, Jerry F. Stults, Jan P. E. Tellings
-
Patent number: 5583247Abstract: Ethylenically unsaturated monomers are protected from premature polymerization during manufacture and storage by the incorporation therein of an effective stabilizing amount of a 7-substituted quinone methide compound.Type: GrantFiled: April 14, 1995Date of Patent: December 10, 1996Assignee: Ciba-Geigy CorporationInventors: Peter Nesvadba, Samuel Evans, Matthew E. Gande, Volker H. von Ahn, Roland A. E. Winter
-
Patent number: 5498791Abstract: A synergistic mixture of a carbonate and/or bicarbonate with a phosphonate, especially an organoamino methylene phosphonate or an N-oxide thereof, inhibits or reduces nitrosamine contamination during preparation, storage and/or heating of products which are susceptible to contamination with nitrosamine.Type: GrantFiled: January 20, 1995Date of Patent: March 12, 1996Assignee: Albright & Wilson, LimitedInventors: Michael Blezard, Glyn R. Jones, Moharam Ghadimi
-
Patent number: 5442113Abstract: A synergistic mixture of a carbonate and/or bicarbonate with a phosphonate, especially an organoamino methylene phosphonate or an N-oxide thereof, inhibits or reduces nitrosamine contamination during preparation, storage and/or heating of products which are susceptible to contamination with nitrosamine.Type: GrantFiled: February 1, 1993Date of Patent: August 15, 1995Assignee: Albright & Wilson LimitedInventors: Michael Blezard, Glyn R. Jones, Moharam Ghadimi
-
Patent number: 4738796Abstract: Process for the heat stabilization of alkyl alkoxyalkylidenemalonates in the presence of Lewis acids, such as metal catalytic compounds employed as catalysts during the preparation of the alkyl alkoxyalkylidenemalonates by condensation of a suitable malonate with a suitable ortho ester. The condensation reaction mixture is heated in the presence of a stabilizing compound selected from the group consisting of 8-hydroxyquinolines and organic acid phosphates in an amount sufficient to stabilize the alkyl alkoxyalkylidenemalonates against thermal decomposition.Type: GrantFiled: June 25, 1985Date of Patent: April 19, 1988Assignee: Rhone-Poulenc Specialites ChimiquesInventor: Serge Ratton
-
Patent number: 4692544Abstract: Certain substituted diaryl amines are used to inhibit the polymerization of ethylenically unsaturated monomers; for example, unsaturated carboxylic acids and derivatives thereof.Type: GrantFiled: August 23, 1985Date of Patent: September 8, 1987Assignee: Sandoz Ltd.Inventors: Richard N. Goerner, J. Michael Hipp, Ruth H. Hipp
-
Patent number: 4590009Abstract: Hydrazine is utilized for preventing side reactions during the preparation and storage of polyisocyanates partially blocked with hydroxy amines which are utilized for the introduction of basic functional groups into organic coating compositions which are deposited cathodically in an electrodeposition process. The inhibiting compound is used in the form of hydrazine hydrate at a level of from about 50 to 5000 ppm calculated on the amine used in the reaction.Type: GrantFiled: April 29, 1985Date of Patent: May 20, 1986Assignee: Vianova Kunstharz, A.G.Inventors: Georg Pampouchidis, Herbert Deu
-
Patent number: 4504652Abstract: Disclosed is a method for reducing the odor and/or improving the performance of polyester plasticizers of the type made from a dibasic acid, a polyol, and a chain terminator wherein a molar excess of alcohol ingredients is used. Such improved polyester plasticizer is made by subjecting the polyester plasticizer to a second stage reaction with a treating agent reactive with hydroxyl groups to reduce the hydroxyl value to no more than about 4. Preferably, the low acid number of the initial polyester plasticizer is maintained. The treating agent can be monofunctional or poly-functional, though preferably a difunctional isocyanate is used. Conventional thermoplastic substrates, typified by polyvinyl chloride, can be plasticized with the novel polyester plasticizers of the present invention.Type: GrantFiled: April 25, 1984Date of Patent: March 12, 1985Assignee: Sherex Chemical Company, Inc.Inventors: Charles R. Widder, Don S. Wozniak
-
Patent number: 4431833Abstract: Degradation of E-type prostaglandin compounds is retarded by dissolving or suspending such compounds in formulations containing hydroxylated derivatives of fatty acids having the formula: ##STR1## wherein R.sub.1 is C.sub.2 -C.sub.24 alkyl, R.sub.2 is C.sub.2 -C.sub.24 alkyl and n is an integer from 1-6, denoting from 1 to 6 hydroxyl groups which may be substituted in R.sub.1 or R.sub.2.Type: GrantFiled: December 27, 1982Date of Patent: February 14, 1984Assignee: American Cyanamid CompanyInventors: Shahid A. Lodhi, Bernard Sims
-
Patent number: 4358603Abstract: Degradation of prostaglandins in anhydrous or aqueous pharmaceutically acceptable, water-miscible alcohol solutions is prevented by adding a stabilizing amount of a pharmaceutically acceptable acetal.Type: GrantFiled: April 16, 1981Date of Patent: November 9, 1982Assignee: Syntex (U.S.A.) Inc.Inventor: Cheng-Der Yu
-
Patent number: 4355183Abstract: Inhibition of the formation of color bodies and color-forming materials and other contaminants and/or decolorization of discolored sulfur-containing organic compounds containing divalent sulfur by addition of a small amount of oxalic acid.Type: GrantFiled: August 8, 1979Date of Patent: October 19, 1982Assignee: Phillips Petroleum CompanyInventors: Martin E. Nash, Edward E. Huxley
-
Patent number: 4178454Abstract: The degradation of prostaglandins E is prevented or minimized by combining prostaglandins E with methylhesperidin.Type: GrantFiled: October 11, 1978Date of Patent: December 11, 1979Assignee: Toray Industries, Inc.Inventors: Masanobu Naruto, Kiyotaka Ohno, Norio Naruse
-
Patent number: 4160864Abstract: An adhesive composition comprising monomeric methyl allyl methylenemalonate is useful for bonding together a wide range of materials.Type: GrantFiled: September 7, 1976Date of Patent: July 10, 1979Assignee: Eastman Kodak CompanyInventors: Ignazio S. Ponticello, John M. McIntire