Perhalate Esters (i.e., Compounds Having The -o-halo(=o)(=o)(=o) Group Bonded Directly To Carbon, Which Carbon May Be Single Bonded To Any Atom But May Be Multiple Bonded Only To Carbon) Patents (Class 560/306)
  • Patent number: 6323181
    Abstract: The present invention provides illudin analogs of the general formula I: wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising compounds of formula I, intermediates and processes useful for preparing compounds of formula I, and methods comprising inhibiting tumor growth or treating cancer by administering one or more compounds of formula I.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: November 27, 2001
    Assignee: The Regents of the University of California
    Inventors: Trevor C. McMorris, Michael J. Kelner