Oxygen Bonded Directly To The Hexavalent Sulfur Of The -s(=o)(=o)-s- Group (i.e., Thiosulfate Esters) Patents (Class 560/308)
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Patent number: 8450390Abstract: The present invention provides both crosslinked polymer compositions capable of forming hydrogels upon exposure to an aqueous environment and thiosulfonate hydrogel-forming components. The thiosulfonate hydrogel-forming components of the invention are preferably multi-arm thiosulfonate polymer derivatives that form a crosslinked polymer composition when exposed to a base without requiring the presence of a second cross-linking reagent, redox catalyst, or radiation. Methods for forming hydrogel compositions, as well as methods for using the hydrogels, are also provided.Type: GrantFiled: July 20, 2012Date of Patent: May 28, 2013Assignee: Nektar TherapeuticsInventors: Zhihao Fang, Michael D. Bentley
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Patent number: 8247598Abstract: The present invention provides both crosslinked polymer compositions capable of forming hydrogels upon exposure to an aqueous environment and thiosulfonate hydrogel-forming components. The thiosulfonate hydrogel-forming components of the invention are preferably multi-arm thiosulfonate polymer derivatives that form a crosslinked polymer composition when exposed to a base without requiring the presence of a second cross-linking reagent, redox catalyst, or radiation. Methods for forming hydrogel compositions, as well as methods for using the hydrogels, are also provided.Type: GrantFiled: December 14, 2011Date of Patent: August 21, 2012Assignee: Nektar TherapeuticsInventors: Zhihao Fang, Michael D. Bentley
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Publication number: 20120088927Abstract: The present invention provides both crosslinked polymer compositions capable of forming hydrogels upon exposure to an aqueous environment and thiosulfonate hydrogel-forming components. The thiosulfonate hydrogel-forming components of the invention are preferably multi-arm thiosulfonate polymer derivatives that form a crosslinked polymer composition when exposed to a base without requiring the presence of a second cross-linking reagent, redox catalyst, or radiation. Methods for forming hydrogel compositions, as well as methods for using the hydrogels, are also provided.Type: ApplicationFiled: December 14, 2011Publication date: April 12, 2012Applicant: Nektar TherapeuticsInventors: Zhihao Fang, Michael D. Bentley
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Publication number: 20100147770Abstract: A composition and process are described that provide for selective capture of targeted materials, including metals and chemical targets. The composition includes an activated carbon scaffold that is chemically modified to include ligands with a high affinity for selective capture of metals and chemical targets. The invention finds use, e.g., as heavy metal sorbents, as catalyst supports, in analytical applications such as ion chromatography, and in devices such as analytical instruments and chemical sensors.Type: ApplicationFiled: December 12, 2008Publication date: June 17, 2010Inventors: Glen E. Fryxell, William D. Samuels
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Patent number: 7217834Abstract: The invention relates to a novel process for preparing salts of S-alkyl esters of thiosulphuric acid by reacting organic dihalides with thiosulphates in water.Type: GrantFiled: April 14, 2005Date of Patent: May 15, 2007Assignee: Lanxess Deutschland GmbHInventor: Hartmuth Buding
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Patent number: 7078551Abstract: A blocked mercaptosilane of the structure: G-C(?O)—S—CH2CH2CH2SiX3 is disclosed wherein each X is an independently selected RO— group or R— group wherein each R is independently selected from the group consisting of hydrogen, alkyl that may or may not contain unsaturation, alkenyl groups, aryl groups, and aralkyl groups, such moieties other than hydrogen having from 1 to 18 carbon atoms, at least one X is RO—, and G is a monovalent alkyl group.Type: GrantFiled: April 30, 2004Date of Patent: July 18, 2006Assignee: General Electric CompanyInventors: Richard W. Cruse, Robert J. Pickwell, Eric Raymond Pohl, Keith J. Weller
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Patent number: 7074876Abstract: Disclosed herein is a blocked mercaptosilane selected from the group consisting of [[(ROC(?O))p—(G)j]k—Y—S]r—G—(SiX3)s; and??(1) [(X3Si)q—G]a—[Y—[S—G—SiX3]b]c??(2) wherein Y is a polyvalent species (Q)zA(?E) selected from the group consisting of —C(?NR)—; —SC(?NR)—; —SC(?O)—; —OC(?O)—; —S(?O)—; —S(?O)2—; —OS(?O)2—; (—NR)S(?O)2—; —SS(?O)—; —OS(?O)—; (—NR)S(?O)—; —SS(?O)2—; (—S)2P(?O)—; —(—S)P(?O)—; —P(?O)(—)2; (—S)2P(?S)—; —(—S)P(?S)—; —P(?S)(—)2; (—NR)2P(?O)—; (—NR)(—S)P(?O)—; (—O)(—NR)P(?O)—; (—O)(—S)P(?O)—; (—O)2P(?O)—; —(—O)P(?O)—; —(—NR)P(?O)—; (—NR)2P(?S)—; (—NR)(—S)P(?S)—; (—O)(—NR)P(?S)—; (—O)(—S)P(?S)—; (—O)2P(?S)—; —(—O)P(?S)—; and —(—NR)P(?S)—; wherein the atom A attached to unsaturated heteroatom E is attached to the sulfur which in turn is linked via a group G to the silicon atom; each R is chosen independently from hydrogen, straight, cyclic, or branched alkyl that may or may not contain unsaturation, alkenyl groups, aryl groups, and aralkyl groups, with each R containing from 1 to 18 cType: GrantFiled: November 9, 2001Date of Patent: July 11, 2006Assignee: General Electric CompanyInventors: Richard W. Cruse, Robert J. Pickwell, Keith J. Weller, Eric R. Pohl
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Patent number: 6608125Abstract: A blocked mercaptosilane of the structure: G—C(═O)—S—CH2CH2CH2SiX3 is disclosed wherein each X is an independently selected RO— group wherein each R is independently selected from the group consisting of hydrogen, alkyl that may or may not contain unsaturation, alkenyl groups, aryl groups, and aralkyl groups, such moieties other than hydrogen having from 1 to 18 carbon atoms, and G is a monovalent alkyl of from 2 to 12 carbon atoms.Type: GrantFiled: November 9, 2001Date of Patent: August 19, 2003Assignee: Crompton CorporationInventors: Richard W. Cruse, Robert J. Pickwell, Keith J. Weller, Eric R. Pohl
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Patent number: 6380400Abstract: The present invention relates to methods of making dihydropyrone HIV inhibitors.Type: GrantFiled: October 31, 2000Date of Patent: April 30, 2002Inventors: Victor Fedij, Christopher Andrew Gajda, Brian Keith Huckabee, Brian Stuart Moon, Kenneth Thomas Porter, Denis Martin Sobieray, Timothy Lee Stuk, Bradley Dean Tait, James Norton Wemple
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Patent number: 5973178Abstract: A compound of the formula: ##STR1## wherein: A is hydrogen, a substituted or unsubstituted C.sub.1 to C.sub.4 alkyl, a substituted or unsubstituted C.sub.1 to C.sub.4 alkoxy or a substituted or unsubstituted phenyl;W is a substituted or unsubstituted phenylene or a substituted or unsubstituted naphthylene;Y is--CH.sub.2 --CH.sub.2 --Z wherein Z is selected from --OSO.sub.3 H, --SSO.sub.3 H, --OPO.sub.3 H, --OCOCH.sub.2 --Cll.sub.3, Cl, Br or F; andm is 1 or 2, e is 0 or 1,with the sum of e+m=2.Type: GrantFiled: May 20, 1998Date of Patent: October 26, 1999Assignee: DyStar L.P.Inventors: Thomas S. Phillips, Ronald P. Pedemonte
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Patent number: 5606092Abstract: A monoazo compound of the following formula, ##STR1## wherein D is phenylene or naphthylene; X is halogeno, pyridinio or ##STR2## B is --OR.sub.3, --SR.sub.4, ##STR3## in which R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are each hydrogen, alkyl, phenyl, naphthyl or benzyl, r is 0 or 1, and E is O, SO, SO.sub.2, CH.sub.2 or NR.sub.8, in which R.sub.8 is hydrogen or C.sub.1 -C.sub.4 alkyl; R, R.sub.1, R.sub.2 and R.sub.7 are each hydrogen or alkyl; A.sub.1, A.sub.2 and A.sub.3 are each phenylene, naphthylene or alkylene; Z.sub.1, Z.sub.2 and Z.sub.3 are each --SO.sub.2 CH.dbd.CH.sub.2 or --SO.sub.2 CH.sub.2 CH.sub.2 Y, in which Y is a splittable group; and p is 0 or 1; which compound is useful for dyeing or printing fiber materials to obtain a product dyed or printed in a color superior in various fastness properties with superior build-up property.Type: GrantFiled: October 20, 1995Date of Patent: February 25, 1997Assignee: Sumitomo Chemical Company, LimitedInventors: Masayuki Miki, Kingo Akahori, Yutaka Kayane, Takeshi Washimi
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Patent number: 5405993Abstract: There are described formazan dyes of the formula ##STR1## where n is 1 or 2,Kat.cndot. is the equivalent of a cation,Me is copper or nickel,X is a radical of the formula CO-O or SO.sub.2 -O,Y is vinyl or a radical of the formula C.sub.2 H.sub.4 -Q, where Q is a group which is detachable under alkaline reaction conditions,the ring A may be substituted and benzofused,the ring B is substituted and may be benzofused, andthe ring C may be substituted,the use thereof for dyeing or printing hydroxyl- or nitrogen-containing organic substrates, and novel hydrazones.Type: GrantFiled: August 9, 1994Date of Patent: April 11, 1995Assignee: BASF AktiengesellschaftInventors: Claus Marschner, Manfred Patsch
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Patent number: 5290810Abstract: A compound of the formula ##STR1## in which R.sup.1 and R.sup.2 taken together represent a polymethylene chain having 3 or 4 carbon atoms, or a polymethylene chain having 3 or 4 carbon atoms substituted by at least one lower alkyl radical having 1 to 4 carbon atoms, R.sup.3 is hydrogen, hydrocarbyl or substituted hydrocarbyl and X represents cyano, a group --SO.sub.3 M or a group --S--R.sup.4 where M is hydrogen or an alkali metal such as sodium and R.sup.4 is hydrocarbyl or substituted hydrocarbyl. Typically R.sup.1 and R.sup.2 complete a cyclopentene ring, R.sup.3 is alkyl such as methyl and X is a group --SO.sub.3 Na. The compounds have microbiological activity.Type: GrantFiled: September 24, 1991Date of Patent: March 1, 1994Assignee: Imperial Chemical Industries PLCInventor: Peter W. Austin
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Patent number: 4898944Abstract: Precursors for the preparation of fiber-reactive triphendioxazine dyestuffs correspond to the general formulas: ##STR1## in which Y' is a vinyl, a beta-hydroxyethyl or an ethyl group which contains in the beta-position a substituent which can be eliminated by an alkali;T is an optionally substituted alkyl (e.g.Type: GrantFiled: October 27, 1988Date of Patent: February 6, 1990Assignee: Hoechst AktiengesellschaftInventors: Gunther Schwaiger, Hartmut Springer, Walter Helmling
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Patent number: 4659856Abstract: Compounds of the general formula (1) ##STR1## in which the Zs, preferably identical to each other, each denote a hydroxy group or a sulfato, thiosulfato or phosphato group. They can be prepared by first converting biphenyl by sulfochlorination into biphenyl-4,4'-disulfochloride, then reducing the latter with an alkali metal or alkaline earth metal sulfite or hydrogensulfite to sulfinic acid, and in turn reacting the latter with ethylene oxide to give 4,4'-bis-(.beta.-hydroxyethylsulfonyl)-biphenyl, which can be esterified in conventional manner. They are used for modifying and improving the physical and coloristic properties of materials made of natural and/or synthetic polyamide fibers and/or polyurethane fibers and as auxiliaries in dyeing processes for such fiber materials.Type: GrantFiled: September 12, 1985Date of Patent: April 21, 1987Assignee: Hoechst AktiengesellschaftInventors: Hartmut Springer, Gerd Konig
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Patent number: 4643994Abstract: This invention relates to novel organic trithio oxides of the formula:R.sup.1 --X --R--X.sup.1 --R.sup.1wherein R is selected from --CH.sub.2 CH.dbd.CH--, ##STR1## and (CH.sub.2).sub.3 ; X is selected from ##STR2## X.sup.1 is selected from --S--S, ##STR3## and, each R.sup.1 is independently selected from carboxyalkyl, alkoxy, alkylthio, amino, alkylamino and acyl substituted and unsubstituted lower alkyl, lower alkenyl, lower alkynyl, phenyl and lower alkylphenyl; provided when R is --CH.sub.2 CH.dbd.CH--, X is ##STR4## and X.sup.1 is --S--S--, then R.sup.1 is not in both instances --CH.sub.2 CH.dbd.CH.sub.2.This invention also relates to a method of preparing the above-identified compounds by heating and further oxidizing various oxides of organic disulfides and to antithrombotic uses of the compounds.Type: GrantFiled: December 17, 1984Date of Patent: February 17, 1987Assignee: The Research Foundation of State University of New YorkInventors: Eric Block, Saleem Ahmad
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Patent number: 4587296Abstract: Additives for rubber compositions, giving vulcanisates having improved retention of optimum physical properties, are compounds containing two or more groups of the formula --S--SO.sub.2 R linked by an organic bridging group, or polymers containing two or more groups of the formula --S--SO.sub.2 R attached to an organic polymer chain, where R represents (a) a radical OM where M is a monovalent metal, the equivalent of a multivalent metal, a monovalent in derived by the addition of a proton to a nitrogenous base, or the equivalent of a multivalent ion derived by the addition of two or more protons to a nitrogenous base, or (b) an organic radical selected from aliphatic, cycloaliphatic, aromatic and heterocyclic radicals, and radicals which are combinations of any two or more such radicals.Type: GrantFiled: April 11, 1985Date of Patent: May 6, 1986Assignee: Monsanto Europe, S.A.Inventor: Philippe G. Moniotte