Persulfonate Esters (i.e., Compounds Having The -s(=o)(=o)-o-o- Group, Wherein The Terminal Oxygen Is Bonded Directly To Carbon, Which Carbon May Be Single Bonded To Any Atom But May Be Multiple Bonded Only To Carbon) Patents (Class 560/318)
  • Inhibitors of histone deacetylase
    Patent number: 6541661
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: April 1, 2003
    Assignee: MethylGene, Inc.
    Inventors: Daniel Delorme, Rejean Ruel, Rico Lavoie, Carl Thibault, Elie Abou-Khalil
  • Catalytic process for converting lower alkanes to esters, alcohols, and to hydrocarbons
    Patent number: 5306855
    Abstract: This invention is a process for converting lower alkanes into their corresponding esters and optionally into various intermediates (such as alcohols) and other liquid hydrocarbons. The alkanes are oxidatively converted to oxy-esters at high selectivity and conversion and at practical reaction rates using at least catalytic amounts of certain class "B" metals and/or metal ions defined by the Pearson definition as "soft" or "borderline". Desirable catalysts comprise such metals as Pd, Tl, Pt, Hg, and Au. If so desired, the alkyl oxy-esters may be converted to alcohols or other intermediates such as alkyl halides. The oxy-esters, alcohols, and other intermediates may optionally be converted to liquid hydrocarbons such as gasoline.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: April 26, 1994
    Assignee: Catalytica, Inc.
    Inventors: Roy A. Periana, Douglas J. Taube, Henry Taube, Eric R. Evitt
  • Process for converting lower alkanes to esters
    Patent number: 5233113
    Abstract: This invention is a process for converting lower alkanes into their corresponding esters and optionally into various intermediates (such as methanol) and other liquid hydrocarbons. The alkanes are oxidatively converted to oxy-esters at high selectivity using catalytic amounts of a Group VIII noble metal. If so desired, the alkyl oxy-esters may be converted to alcohols or other intermediates such as alkyl halides. The oxy-esters, alcohols, and other intermediates may optionally be converted to liquid hydrocarbons such as gasoline.
    Type: Grant
    Filed: February 15, 1991
    Date of Patent: August 3, 1993
    Assignee: Catalytica, Inc.
    Inventors: Roy A. Periana, Eric R. Evitt, Henry Taube
  • O.sup.17 isotopic peroxides
    Patent number: 5154912
    Abstract: The peroxides which include the O.sup.17 isotope, especially the hydrogen peroxides and peroxides and hydroperoxides prepared therefrom, are well adapted as nonradioactive labeled compounds for use in the medicinal and biological arts.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: October 13, 1992
    Assignee: Atochem
    Inventors: Jean-Pierre Schirmann, Jean-Jacques Barieux
  • Inhibitors of histone deacetylase
    Patent number: RE39850
    Abstract: The invention relates to the inhibition of histone deactylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: September 18, 2007
    Assignee: Methylgene, Inc.
    Inventors: Daniel Delorme, Rico Lavoie, Carl Thibault, Elie Abou-Khalil, Rejean Ruel
  • Inhibitors of histone deacetylase
    Patent number: RE43343
    Abstract: The invention relates to the inhibition of histone deactylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: May 1, 2012
    Assignee: Methylgene Inc.
    Inventors: Daniel Delorme, Rejean Ruel, Rico Lavoie, Carl Thibault, Elie Abou-Khalil