1,4a-dimethylhydrophenanthrene-1- Carboxylic Acid Patents (Class 560/7)
  • Patent number: 8686178
    Abstract: The present invention is correlated with a derivative of 18?-glycyrrhetinic acid apt to suppressing cancer cells, which is selected from a group comprising of structure I and structure II: wherein residue R1 is selected from one of CH3 and CH2C6H5, residue R2 is selected from one of COOCH3, COOCH2CH3, COOCH(CH3)2, CONHCH2CH3, CONHCH2CH2CH3, and CONHCH2(CH3)2, and residue R3 is selected from one of COOCH2CH3, COOCH(CH3)2, CONHCH2CH3, CONHCH2CH2CH3, and CONHCH2(CH3)2.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: April 1, 2014
    Assignee: Kaohsiung Medical University
    Inventors: Chun-Nan Lin, Kai-Wei Lin, A-Mei Huang, Tzyh-Chyuan Hour, Shyh-Chyun Yang, Yeong-Shiau Pu, Jan-Gowth Chang
  • Publication number: 20120322969
    Abstract: A dehydroabietic acid polymer including a skeleton represented by following formula (A) as a repeating unit: wherein, in formula (A), L represents a divalent organic group.
    Type: Application
    Filed: December 21, 2010
    Publication date: December 20, 2012
    Applicant: FUJIFILM CORPORATION
    Inventors: Kozo Sato, Toshimitsu Sakuma
  • Patent number: 6998501
    Abstract: Triglycerides and cholesterol in the bloodstream are important factors in the development of cardiovascular disease. The present invention discloses a nutritional supplement comprising a sterol and an omega-3 fatty acid, or an ester thereof, for lowering cholesterol and triglyceride levels in the bloodstream of a subject. Preferably, the sterol and omega-3 fatty acid are together in the form of an ester.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: February 14, 2006
    Assignee: Ocean Nutrition Canada Limited
    Inventors: Jeffrey L. C. Wright, Jaroslav A. Kralovec
  • Patent number: 6291719
    Abstract: The present invention relates to a method of catalyzing etherification, esterification, hydration, ether cleavage, isomerization alkylation, or other reactions which are catalyzable with an acid or molecular sieve catalyst. Said reactions are conducted using a novel, dual functional catalyst prepared with active components and a small amount of binder, wherein said dual functional catalyst comprises cylindrical pellets which are molded such that a cross-section or each pellet has a window lattice shape with external teeth, or a star shape with inner spokes.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: September 18, 2001
    Assignees: China Petro-Chemical Corporation, Qilu Petro-Chemical Corporation Sinopec
    Inventors: Buliang Gao, Jinyong Zhang, Jinshan Wang, Xingren Hao, Zaiqun Yu, Wei Wang
  • Patent number: 6051590
    Abstract: The compounds of Formula I are useful as immunosuppressive agents.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: April 18, 2000
    Assignee: Merck & Co., Inc.
    Inventors: Jianming Bao, Frank Kayser, Robert K. Baker, Shouwu Miao, William H. Parsons, Kathleen M. Rupprecht
  • Patent number: 5596123
    Abstract: Stable .alpha.-substituted boronic esters, e.g. for use in peptide synthesis, are prepared by reacting a substituted alkene of the formula: ##STR1## with a disubstituted borane of the formula: ##STR2## wherein: (i) R.sup.1 and R.sup.2 are each selected from various groups which are preferably not leaving groups;(ii) X is halogen or other leaving group;(iii) Y is H or lower alkyl;(iv) Q.sup.1 and Q.sup.2 are each selected from various groups which are preferably such that the borane is non-hydrolyzable, and particularly Q.sup.1 and Q.sup.2 together may represent a residue of a diol such as catechol or pinanediol.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: January 21, 1997
    Assignee: Thrombosis Research Institute
    Inventors: Said M. A. Elgendy, John J. Deadman, Geeta Patel, Donovan S. Green, Jehan A. Baban, Vijay V. Kakkar, Goran K. Claeson
  • Patent number: 5302741
    Abstract: D(+)-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)propionic acid, an important intermediate in the synthesis of diltiazem hydrochloride, is obtained in better yields and high optical purity by a novel resolution process comprising the reaction of 2 moles of the (.+-.) racemic acid with 1 mole of quinine and 1 mole of a base in a suitable polar solvent system to form a salt of the D(+) acid and quinine which precipitates; separating said salt and decomposing it with a strong base.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: April 12, 1994
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Ramy Lidor, Claude Singer
  • Patent number: 5241100
    Abstract: Disclosed are 2,4,6-trialkyl-3-hydroxybenzyl esters of monocarboxylic resin acids and olefin polymer compositions stabilized therewith.
    Type: Grant
    Filed: July 15, 1991
    Date of Patent: August 31, 1993
    Assignee: Himont Incorporated
    Inventor: Charles M. Wright
  • Patent number: 5194472
    Abstract: Toner particles comprising a polyester binder and a charge control agent are provided wherein such agent is a quaternary ammonium salt having one or more ester-containing moieties. Such an ester-containing salt causes toner particles to display lower fusing temperature, improved paper adhesion indexes, and improved polyester binder compatibility compared to nonesterified salts.
    Type: Grant
    Filed: April 24, 1992
    Date of Patent: March 16, 1993
    Assignee: Eastman Kodak Company
    Inventors: John C. Wilson, Lawrence P. DeMejo, Alexandra D. Bermel
  • Patent number: 5183922
    Abstract: The present invention relates to a process for the separation of the enantiomers of threo-2-hydroxy-3-(2'- aminophenylthio)-3-(4"-methoxyphenyl)-propionic acid, which is an important intermediate in the synthesis of pharmacologically active compounds, by means of the direct crystallization of the relevant cyclohexylaminic salt.According to a preferred form of practical embodiment of the present invention, the optically pure acid is recovered as the hydrochloride of the corresponding methyl ester.
    Type: Grant
    Filed: November 19, 1990
    Date of Patent: February 2, 1993
    Assignee: FIS - Fabbrica Italiana Sintetici S.p.A.
    Inventors: Amleto Rizzi, Gaetano Marchioro
  • Patent number: 5110977
    Abstract: Toner particles comprising a polyester binder and a charge control agent are provided wherein such agent is a quaternary ammonium salt having one or more ester-containing moieties. Such an ester-containing salt causes toner particles to display lower fusing temperature, improved paper adhesion indexes, and improved polyester binder compatibility compared to nonesterified salts.
    Type: Grant
    Filed: February 14, 1990
    Date of Patent: May 5, 1992
    Assignee: Eastman Kodak Company
    Inventors: John C. Wilson, Lawrence P. DeMejo, Alexandra D. Bermel
  • Patent number: 4238380
    Abstract: The disodium ethoxylated rosin half esters of sulfosuccinic acid prepared from the 1-5 mole rosin ethoxylates are disclosed as foam stabilizers for a variety of latices as well as latex compositions containing same which are processable into a non-gelling, heat-curable solid foam suitable for use as foam carpet backing and the method of preparing the latex compositions.
    Type: Grant
    Filed: May 7, 1979
    Date of Patent: December 9, 1980
    Assignee: Westvaco Corporation
    Inventor: John A. Alford