Containing -c(=x)-x-n(=o) Or -c(=x)-x-s(=o)(=o)-, Wherein The X's May Be The Same Or Diverse Chalcogens Patents (Class 562/879)
  • Publication number: 20120190820
    Abstract: Provided are methods for forming a reactive S-nitroso thioacid (NTA), comprising nitrosation of a thioacid with a nitrosation reagent. Also provided are methods for: acylating a nucleophile including selective acylation with a high degree of selectivity toward amines over hydroxyls; amide or peptide bond formation; forming a dipeptide or polypeptide; and peptide coupling/ligation, comprising use of thioacid and amine starting materials, wherein the reactions are mediated by very reactive S-nitroso thioacid (NTA) intermediates enabling extremely fast reactions under mild conditions, providing for broad applications.
    Type: Application
    Filed: January 26, 2012
    Publication date: July 26, 2012
    Inventors: Ming Xian, Jia Pan
  • Patent number: 6753431
    Abstract: There is disclosed an advantageous mixed acid anhydride production method of formula (1): R1C(O)OY(O)n(R2)p  (1) wherein R1, R2 and Y denote the same as defined below, n and p denote an integer of 1 or 2, which is characterized by adding a carboxylic acid of formula (2); R1COOH  (2) wherein R1 denotes a hydrogen atom, an optionally substituted alkyl group or the like, an organic base to a solution of a carboxylic acid activating agent of formula (3); (R2)pY(O)nX  (3) wherein R2 denotes an optionally substituted aliphatic hydrocarbyl group or the like, Y denotes a carbon atom, a phosphorus atom, or a sulfur atom, and X denotes a chlorine atom or the like.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: June 22, 2004
    Assignee: Sumitomo Chemical Company Limited
    Inventors: Takashi Miki, Hideki Ushio, Isao Kurimoto
  • Patent number: 6441230
    Abstract: Material and process of preparing such material, of the formula where R1 is a linker and C(R2P(R3)2)3 group is a triphos moiety; and wherein R1 is selected from branched and linear alkyl group and alkyl carbonyl group optionally substituted with functional groups comprising carbonyl, alkoxy, hydroxy, amino, nitro, carboxylic or sulfonic acid and esters or amides thereof; R2 are methylene (CH2) or substituted methylene groups; R3 are linear or branched alkyl or phenyl or substituted phenyl groups; polymer is any polymer containing aromatic groups, comprising polystyrene, poly-vinyl pyridine, poly pyrrole, poly pyrrolidone or derivatives thereof. The material impregnated with a transition metal has catalytic properties. The preparation of the material involves the use of an acylating agent having the formula CF3SO3C(O)C(H2X)3 or an anhydride thereof, where X is a halogen.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: August 27, 2002
    Assignee: Haldor Topsoe A/S
    Inventors: Niels Christian SchiĆødt, Finn Joensen
  • Patent number: 5120457
    Abstract: Products derived from the reaction of organic or metal salts of diorganodithiocarbamic acids with benzenesulfonyl halides, impart excellent multifunctional antiwear and antioxidant properties to lubricating oil compositions.
    Type: Grant
    Filed: September 10, 1990
    Date of Patent: June 9, 1992
    Assignee: Mobil Oil Corp.
    Inventors: Angeline B. Cardis, Abraham O. M. Okorodudu
  • Patent number: 4857660
    Abstract: 1-Phenyl-3-azabicyclo[3.1.1]-heptane-2,4-diones of the formula ##STR1## in which R.sub.1 represents hydrogen or a saturated or unsaturated, aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aromatic or aromatic-aliphatic hydrocarbon radical having up to and including 18, preferably up to and including 12, carbon atoms, R.sub.2 represents hydrogen, lower alkyl, sulpho or acyl, R.sub.3 represents hydrogen or lower alkyl and R.sub.4 represents hydrogen, lower alkyl, phenyl or phenyl substituted by --N(R.sub.2)(R.sub.3), and salts of these compounds, have valuable pharmacological properties, are effective as aromatase inhibitors and can therefore be used for the treatment of hormone-dependent diseases, especially mammary carcinoma.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: August 15, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Alex Alder, Jaroslav Stanek, Daniel Bellus