Thiocarbazides Or Thiosemicarbazides (i.e. Hnh-nh-c(=s)-hnh, Wherein The N Bonded Directly To The Thiourea N Is An Amino N And Substitution May Be Made For Hydrogen Only) Patents (Class 564/18)
  • Patent number: 4294919
    Abstract: A direct positive silver halide photographic light-sensitive material is described, comprising a support having coated thereon a light-sensitive silver halide photographic emulsion layer and a hydrophilic colloid layer, at least one of said layers containing a compound represented by the formula (I): ##STR1## wherein R.sup.1 represents R.sup.6 or R.sup.6 CO--; and R.sup.6 represents an aliphatic group, an aromatic group, a heterocyclic aromatic group or hydrogen; R.sup.2 and R.sup.4, which may be the same or different, each represents an aliphatic group, an aromatic group, a heterocyclic aromatic group or a hydrogen atom; or R.sup.1 and R.sup.2 together can form a ring; R.sup.3 represents hydrogen or an aliphatic group; R.sup.5 represents Y or X--A--Y wherein X and Y, which may be the same or different, each represents a divalent aromatic group; and A represents a divalent group selected from --CONH--, --NHCONH--, --SO.sub.2 NH--, --B--CONH-- and --B--SO.sub.
    Type: Grant
    Filed: June 6, 1980
    Date of Patent: October 13, 1981
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Nobuyuki Tsujino, Shigeo Hirano
  • Patent number: 4294972
    Abstract: Compounds of the formula (I): ##STR1## wherein n is 3 to 5;Y is --CH.sub.2 --CH.sub.2, --CH.dbd.CH-- or C.tbd.C--;L is O or S;R.sub.1 is C.sub.1-4 alkyl;R.sub.2 is hydrogen, C.sub.1-4 alkyl or phenyl;R.sub.3 is hydroxy or protected hydroxy;R.sub.4 is hydrogen, C.sub.1-9 alkyl, C.sub.3-8 cycloalkyl, phenyl, naphthyl, any of which phenyl moieties or naphthyl moieties may be substituted by one or more halogen, trifluoromethyl, C.sub.1-6 alkyl, hydroxy, C.sub.1-6 alkoxy, phenyl C.sub.1-6 alkoxy or nitro groups; orR.sub.2 and R.sub.4 taken with the carbon atom to which they are joined represent a C.sub.5-8 cycloalkyl group; and R.sub.5 is C.sub.1-6 alkyl, having similar activity to natural prostaglandins, a process for their preparation, intermediates useful in that process and pharmaceutical compositions containing them.
    Type: Grant
    Filed: June 14, 1979
    Date of Patent: October 13, 1981
    Assignee: Beecham Group Limited
    Inventors: Frederick Cassidy, Alexander C. Goudie
  • Patent number: 4282031
    Abstract: The present invention is directed to a class of novel 1-benzoyl-3-thiosemicarbazides which are useful as plant growth regulants. The present invention is also directed to methods and formulations for plant growth regulation.
    Type: Grant
    Filed: August 2, 1979
    Date of Patent: August 4, 1981
    Assignee: Gulf Oil Corporation
    Inventors: Jerry L. Rutter, James L. Ahle
  • Patent number: 4258181
    Abstract: This disclosure describes anthracene-9,10-bis-carbonyl-hydrazones and derivatives thereof useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors, and for inducing the regression and/or palliation of leukemia and related cancers.
    Type: Grant
    Filed: May 7, 1979
    Date of Patent: March 24, 1981
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Frederick E. Durr
  • Patent number: 4256661
    Abstract: In the production of thiosemicarbazide comprising the steps of reacting hydrazine and ammonium thiocyanate to form hydrazinium thiocyanate and by-product ammonia, and heating the hydrazinium thiocyanate to effect isomerization thereof to thiosemicarbazide, the improvement which comprises removing the ammonia from the hydrazinium thiocyanate prior to isomerization thereof, whereby the thiosemicarbazide is produced in high yield and purity. Advantageously at least about 80% of the ammonia is removed by steam stripping and/or vacuum distillation and the subsequent isomerization is effected by prolonged heating in the presence of a carbonyl compound such as acetone or acetaldehyde. The thiosemicarbazide is recovered by cooling to effect crystallization, followed by filtration, the mother liquor being recycled as solvent medium for the next batch.
    Type: Grant
    Filed: November 1, 1979
    Date of Patent: March 17, 1981
    Assignee: Mobay Chemical Corporation
    Inventors: Danny B. Barton, Chester W. Halbleib, Jack J. Lonsinger
  • Patent number: 4252962
    Abstract: Disclosed is a process for producing 2-amino or 2-(lower alkyl or phenyl)amino-5-mercapto-1,3,4-thiadiazole compounds by reacting the corresponding thiosemicarbazide with an alkali metal lower alkyl xanthate salt.
    Type: Grant
    Filed: March 24, 1980
    Date of Patent: February 24, 1981
    Assignee: Olin Corporation
    Inventor: Eugene F. Rothgery