O-esters (i.e., H Of Oxime -oh Replaced By Ester Forming Group) Patents (Class 564/254)
  • Patent number: 5650444
    Abstract: A compound of the following structure: ##STR1## wherein, when R.sub.8 =H: R.sub.1 =alkyl, cycloalkyl, arylalkyl, aryl;R.sub.2 =cycloalkyl, aryl, C.sub.3 -C.sub.10 alkyl;X,Y=O, S(O).sub.n, NH;Z=CHO, CO.sub.2 R.sub.3, CONHR.sub.4 R.sub.5, CN, COR.sub.6, H, halo, HCN, NHCONR.sub.4 R.sub.5, CONR.sub.4 OR.sub.5, CONR.sub.4 NR.sub.5 R.sub.6, 1-tetrazole, S(O).sub.n OH, S(O).sub.n NR.sub.3 R.sub.4, C.dbd.NOH, C(.dbd.N(OH)NH.sub.2, OCONR.sub.7 R.sub.6, P(O)(OR.sub.4).sub.2, C(.dbd.N(YR.sub.3))R.sub.4, NH.sub.2, SH, OH, OS(O).sub.2 R.sub.3, C(.dbd.NYC(.dbd.O)R.sub.3)R.sub.4, C(O)CO.sub.2 R.sub.3, C(O)CONR.sub.3 R.sub.4, CH(OH)CO.sub.2 R.sub.3, CHFCO.sub.2 R.sub.3, CF.sub.2 CO.sub.2 R.sub.3, CH(OH)CONR.sub.3 R.sub.4, CF.sub.2 CONR.sub.3 R.sub.4, C.dbd.NNH.sub.2, C(.dbd.NOC(.dbd.O)R.sub.3)R.sub.4, C(.dbd.NNHC(.dbd.O)R.sub.3)R.sub.4, C(.dbd.NOH)R.sub.3, C(.dbd.NNR.sub.3)R.sub.4, NHC(.dbd.O)R.sub.6 or C(O)CONH.sub.2 ;R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: July 22, 1997
    Assignee: American Home Products Corporation
    Inventors: Thomas J. Caggiano, Joseph Prol, Jr.
  • Patent number: 5548078
    Abstract: A fungicidal composition for agricultural use, which comprises a compound of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, lower alkyl or cyclo(lower)alkyl; R.sup.3 is lower alkyl or cyclo(lower)alkyl; R.sup.4 and R.sup.5 are each hydrogen, lower alkyl, lower alkoxy, halogen-substituted lower alkyl, lower alkyl-substituted silyl, halogen or nitro; A represents an unsaturated hydrocarbon group, a halogen-substituted unsaturated hydrocarbon group, a phenyl group or a heterocyclic group, among which the phenyl group and the heterocyclic group may be optionally substituted with not more than three substituents; and Z is --CH.sub.2 --, --CH(OH)--, --CO--, --O--, --S--, --NR-- (R being hydrogen or lower alkyl), --CH.sub.2 CH.sub.2 --, --CH.dbd.CH--, ##STR2## --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 SO--, --OCH.sub.2 --, --SCH.sub.2 -- or --SOCH.sub.2 --.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: August 20, 1996
    Assignee: Shionogi Seiyaku Kabushiki Kaisha
    Inventors: Yoshio Hayase, Takahiro Kataoka, Hideyuki Takenaka, Mitsuhiro Ichinari, Michio Masuko, Toshio Takahashi, Norihiko Tanimoto
  • Patent number: 5276187
    Abstract: This invention relates to novel ketoxime carbonates and a process for the synthesis of ketoxime carbonates generally. Ketoxime carbonates are useful in a variety of applications. They may be used for example as pesticides, pharmaceuticals, weed control agents and dye stuff intermediates.
    Type: Grant
    Filed: August 23, 1991
    Date of Patent: January 4, 1994
    Assignee: AlliedSignal Inc.
    Inventors: Halasya Ramanathan, Chempolil T. Mathew
  • Patent number: 5254584
    Abstract: Certain N-acetonylbenzamides exhibit low phytotoxicity and are useful for control of a wide range of fungi, including phytopathogenic fungi of the classes Oomycetes, Ascomycetes, Deuteromycetes and Basidiomycetes.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: October 19, 1993
    Assignee: Rohm and Haas Company
    Inventors: Enrique L. Michelotti, Robert R. Raney, David H. Young
  • Patent number: 5206406
    Abstract: A process for preparing N-ethylhydroxylamine hydrochloride which comprises reacting hydroxylamine hydrochloride with di-t-butyl dicarbonate in the presence of a base thus producing N,O-bis-[(1,1-dimethylethoxy)carbonyl]-hydroxylamine, alkylating said reaction product and then cleaving with acid the tert-butyloxy carbonyl (BOC) portion of the alkylated product.
    Type: Grant
    Filed: August 21, 1992
    Date of Patent: April 27, 1993
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventor: George E. Lee
  • Patent number: 5147879
    Abstract: Hydroximic acid derivatives of the formula ##STR1## These compounds are useful for treating diabetes angiopathy.
    Type: Grant
    Filed: June 28, 1990
    Date of Patent: September 15, 1992
    Assignee: Biorex Kutato-Fejleszto Kft
    Inventors: Peter L. Nagy, Bela Balazs, Maria Boross, Jeno Szilbereky, Gizella Zsila, Lajos braham, Gyorgy Blasko, Bela Gachalyi, Attila Almasi, Gabor Nemet
  • Patent number: 5134167
    Abstract: 1-Azabutadienes of the formula ##STR1## where R.sup.1 and R.sup.2 are each phenyl, biphenyl, naphthyl or pyridyl, and these radicals may be substituted, or are each alkyl which is unsubstituted or substituted, R.sup.3 is substituted or unsubstituted phenyl or a radical OR.sup.4, where R.sup.4 is hydrogen, alkyl or an aromatic or aliphatic acyl group, or R.sup.3 is a radical NHR.sup.5, where R.sup.5 is hydrogen, substituted or unsubstituted phenyl, or the carbamide group, and fungicidal agents containing these compounds.
    Type: Grant
    Filed: July 11, 1990
    Date of Patent: July 28, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Manfred Lauer, Bernhard Zipperer, Norbert Goetz, Gisela Lorenz, Eberhard Ammermann
  • Patent number: 5095087
    Abstract: Disclosed are certain ketoxime-blocked polyisocyanates and polyester compositions containing the ketoxime-blocked polyisocyanates. Also disclosed are thermosetting powder coating compositions comprising one or more polyesters and at least one of the ketoxime-blocked polyisocyanates and articles coated with the powder coating compositions.
    Type: Grant
    Filed: February 25, 1991
    Date of Patent: March 10, 1992
    Assignee: Eastman Kodak Company
    Inventors: J. Stewart Witzeman, Glenn C. Jones
  • Patent number: 5041663
    Abstract: The invention relates to novel oxime ethers of the formula I ##STR1## wherein R.sub.1 is hydrogen, halogen, lower alkyl, lower haloalkyl, lower alkoxy, lower haloalkoxy, lower alkylthio, lower haloalkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower haloalkylsulfinyl, lower haloalkylsulfonyl or nitro, each of R.sub.2 and R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or lower haloalkoxy, and Q is an unsubstituted or substituted lower alkyl, lower alkenyl, lower alkynyl or cycloalkyl group, a lower alkanoyl radical, an aliphatic, cycloaliphatic, aromatic or heterocyclic acyl radical which may be substituted or unsubstituted, a carbonyl or thiocarbonyl radical, an aryl or aralkyl radical, an acylimidomethyl radical, a phthalimidomethyl radical or a heterocyclic radical.These compounds are able to act as antidotes or safeners for protecting cultivated plants from the phytotoxic action of aggressive herbicides.
    Type: Grant
    Filed: December 11, 1990
    Date of Patent: August 20, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Henry Martin, Urs Fricker
  • Patent number: 4946865
    Abstract: A compound of the formula: ##STR1## wherein X is a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.3 alkyl group or a C.sub.1 -C.sub.3 alkoxy group and Y is a hydrogen atom, a halogen atom, a cyano group, a formyl group, an ethylene-dioxymethyl group, a hydroxyl group, a hydroxymethyl group or a group of either one of the formulas: --CH.dbd.N--OR.sup.1, --COOR.sup.2, --CONH--R.sup.2 and --CH(OR.sup.3).sub.2 in which R.sup.1 is a hydrogen atom, a C.sub.1 -C.sub.3 alkyl group, a C.sub.3 -C.sub.5 alkenyl group, a C.sub.3 -C.sub.5 alkynyl group, a halo(C.sub.3 -C.sub.5)alkynyl group or a C.sub.1 -C.sub.3 alkyl group substituted with a phenyl group or a cyano group, R.sup.2 is a hydrogen atom, a C.sub.1 -C.sub.3 alkyl group, a C.sub.3 -C.sub.5 alkenyl group or a C.sub.3 -C.sub.5 alkynyl group and R.sup.3 is a C.sub.1 -C.sub.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: August 7, 1990
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Junya Takahashi, Shigeko Nakamura
  • Patent number: 4910221
    Abstract: Pesticidal novel .alpha.-methylsulphonyl-benzaldoxime derivatives of the formula ##STR1## in which R represents alkyl, alkoxy, halogenoalkyl, halogenoalkoxy or alkenyloxy, aryl or aryloxy which is in each case optionally monosubstituted to polysubstituted by identical or different substituents, aralkyloxy which is optionally monosubstituted to polysubstituted in the aryl radical by identical or different substituents, cycloalkyloxy which is optionally monosubstituted to polysubstituted by identical or different substituents, or a heterocyclic ring which is optionally monosubstituted to polysubstituted by identical or different substituents,X represents hydrogen or halogen, andHal represents halogen.
    Type: Grant
    Filed: April 8, 1988
    Date of Patent: March 20, 1990
    Assignee: Bayer Aktiengesellschaft
    Inventors: Christa Fest, Gerd Hanssler, Wilhelm Brandes
  • Patent number: 4897424
    Abstract: Novel substituted aryloxyphenyl-thioureas, -isothioureas and -carbodiimides of formula I ##STR1## in which R.sub.1 represents C.sub.1 -C.sub.12 alkyl, C.sub.1 -C.sub.12 alkyl mono- or poly-substituted by halogen and/or by C.sub.1 -C.sub.6 alkoxy, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.8 cycloalkyl mono- or poly-substituted by C.sub.1 -C.sub.3 alkyl, or C.sub.3 -C.sub.8 cycloalkyl-C.sub.1 -C.sub.4 alkyl;R.sub.2 represents hydroben or C.sub.1 -C.sub.5 alkyl;R.sub.3 represents a C.sub.1 -C.sub.5 alkyl or C.sub.5 -C.sub.6 cycloalkyl;R.sub.4 represents hydrogen or methyl;R.sub.5 represents a --CH.dbd.CH--.sub.2, --CH.sub.2 --.sub.3 or --CH.sub.2 --.sub.4 bridge in the 2,3- or 3,4-position;Z represents --NH--CS--NH--, --N.dbd.C(SR.sub.6)--NH-- or --N.dbd.C.dbd.N-- andR.sub.6 represents C.sub.1 -C.sub.
    Type: Grant
    Filed: June 9, 1988
    Date of Patent: January 30, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Manfred Boger, Jozef Drabek, Josef Ehrenfreund
  • Patent number: 4894461
    Abstract: 3-(.gamma.-chloropropyl)-6-fluoro-1,2-benzisoxazole is a compound useful in preparing compounds having a neuroleptic utility.
    Type: Grant
    Filed: February 27, 1986
    Date of Patent: January 16, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Larry Davis, Richard C. Effland
  • Patent number: 4886832
    Abstract: Fungicidally active benzaldoxime derivatives of the formula ##STR1## in which R represents alkyl, alkoxy, halgenoalkyl, halogenoalkoxy or alkenyloxy, or aryl or aryloxy, in each case optionally mono- or polysubstituted by identical or different substituents, aralkyloxy which is optionally mono- or polysubstituted in the aryl radical by identical or different substituents, or represents cycloalkoxy which is optionally mono- or polysubstituted by identical or different substituents, or represents a heterocyclic radical which is optionally mono- or polysubstituted by identical or different substituents,R.sup.1 represents hydrogen, halogen, alkyl or alkoxy,R.sup.2 represents hydrogen, alkyl or halogenoalkyl,R.sup.3 represents hydrogen or halogen,R.sup.4 represents halogen andR.sup.5 represents hydrogen or halogen.
    Type: Grant
    Filed: March 10, 1988
    Date of Patent: December 12, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Christa Fest, Kurt Findeisen, Wilhelm Brandes, Stefan Dutzmann, Gerd Hanssler, Paul Reinecke
  • Patent number: 4879314
    Abstract: Dihaloformaldoximes of the formula: ##STR1## wherein R, X, X.sup.1 and Y are as defined herein having biocidal, fungicidal and pesticidal activity are disclosed.
    Type: Grant
    Filed: January 8, 1986
    Date of Patent: November 7, 1989
    Inventor: Adam C. Hsu
  • Patent number: 4816487
    Abstract: New 1-(2-hydroxylaryl)-alkane-1-on-oximes, procedure for their preparation, and their applicability to pharmaceutical preparations. One purpose is to develop 1-(2-hydroxyaryl)-alkane-1-on-oximes with desirable pharmacological properties. The new compounds of Formula I ##STR1## are characterised by pharmacologically valuable properties, in particular by anti-asthmatic, anti-anaphylactic, antiphlogistic, antihypertensive, spasmolytic, antirheumatic, and antithrombotic, potentials and are applicable in human and veterinary medicine to therapy of asthma bronchiale and other allergic diseases, various kinds of inflammatory and rheumatic diseases, and thrombosis.
    Type: Grant
    Filed: March 14, 1985
    Date of Patent: March 28, 1989
    Assignee: Humboldt-Universitaet zu Berlin
    Inventors: Tankred Schewe, Hartmut Kuehn, Joerg Beger, Grupe, Renate, Rapoport, Samuel M., Hans-Joachim Binte, deceased, Juergen Slapke
  • Patent number: 4766152
    Abstract: The present invention relates to novel oximes of the formula ##STR1## wherein U is one of the radicals ##STR2## and R.sub.1 is C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.5 alkenyl, C.sub.3 monohaloalkenyl, C.sub.3 -C.sub.5 alkynyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.2 -C.sub.5 alkoxyalkyl, C.sub.2 -C.sub.5 alkylthioalkyl, or benzyl, which is unsubstituted or substituted at the nucleus,R.sub.2 and R.sub.3 are each independently of the other hydrogen or C.sub.1 -C.sub.3 alkyl,R.sub.4, R.sub.5 and R.sub.6 are each independently of one another hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy or nitro,n is 0 or 1,X is oxygen, sulfur or ##STR3## Y is oxygen, sulfur ##STR4## and Z is oxygen or sulfur;with the proviso that X and Y are not simultaneously oxygen and/or at least one of the radicals R.sub.4, R.sub.5 and R.sub.6 has a meaning other than hydrogen if R.sub.1 is a C.sub.1 -C.sub.
    Type: Grant
    Filed: May 1, 1986
    Date of Patent: August 23, 1988
    Assignee: Ciba-Geigy Corporation
    Inventor: Friedrich Karrer
  • Patent number: 4746678
    Abstract: The invention relates to new phenanthrene derivatives wherein R stand for C.sub.1-10 alkylamino; C.sub.1-10 alkylthio; C.sub.1-5 alkoxy; or phenyl or phenylamino, the two latter groups being optionally substituted on the phenyl ring by one or more identical or different C.sub.1-4 alkyl, C.sub.1-4 alkoxy, nitro, amino, cyano and/or halogen substituent(s) .The compounds of the present invention possess valuable fungicidal properties and may be used in agriculture, horticulture and therapy as active ingredient of fungicidal or antifungal compositions.The compounds of the general Formula I ##STR1## may be prepared by acylating 9,10-phenanthrene-dione-9-oxime or an alkali or alkali earth metal salt thereof.
    Type: Grant
    Filed: June 4, 1986
    Date of Patent: May 24, 1988
    Assignee: EGIS Gyoryszergyar
    Inventors: Pal Benko, Tibor Zsolnai, Marta Kininczky, Laszlo Pallos, Iren Zsolnai nee Csillag, Peter Tetenyi, Jeno Bernath
  • Patent number: 4736055
    Abstract: Oxime sulfonates of formula I ##STR1## wherein Y is a polymerizable unsaturated group or epoxide group or an --OH, --NHR.sup.5, --COOH, COOR.sup.6, --COCl, --CH.sub.2 Hal, --SO.sub.2 Cl or --NCO group, Z is an (x+y)-valent connecting member, R.sup.1 and R.sup.2 are monovalent organic radicals, m is 0 or 1, x is 1 or 2 and y is 1 or 2, can be converted into polymers which can be thermally or photochemically dissociated to form free sulfonic acid groups. Said polymers can therefore be used as photoresists which can be developed with aqueous alkalis.
    Type: Grant
    Filed: April 11, 1986
    Date of Patent: April 5, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Kurt Dietliker, Werner Rutsch, Godwin Berner, Max Hunziker, Christopher G. Demmer
  • Patent number: 4673692
    Abstract: A compound represented by the formula ##STR1## wherein R.sup.1 represents a hydroxyl group, an alkanoyloxy group or a group of the formula ##STR2## in which R.sup.2 represents a hydrogen atom or a lower alkyl group, and R.sup.3 represents a hydrogen atom, a lower alkyl group, an alkanoyl group, a phenyl group, a carbamoyl group or a thiocarbamoyl group, or a salt thereof.The said compound can be prepared by reacting a compound represented by the formula ##STR3## with a compound of the formulaNH.sub.2 --R.sup.1 (III)wherein R.sup.1 is as defined hereinabove, or a salt thereof, and as required, alkanoylating the resulting compound of formula (I) in which R.sup.1 represents a hydroxyl group or an amino group, and as required, converting the resulting compound of formula (I) in which R.sup.1 is the group ##STR4## into its salt, and is useful for the treatment of inflammation, pain or rheumatism.
    Type: Grant
    Filed: October 18, 1985
    Date of Patent: June 16, 1987
    Assignee: Teikoku Hormone Mfg. Co., Ltd.
    Inventors: Yasushi Suzuki, Yukio Hasegawa, Michitaka Sato, Morinobu Saito, Norio Yamamoto, Katsuhiko Miyasaka, Takashi Mikami, Katsuhiko Miyazawa
  • Patent number: 4581365
    Abstract: The invention relates to new trichloroacryloyl oxime compounds of the general formula (I) ##STR1## wherein each of R.sup.1 and R.sup.2 represents a hydrogen atom, a lower alkyl group, a benzyl group, a benzylthio group, a lower alkylthio group, a cycloalkyl group, a halogen atom, a styryl group, a halogenophenylthio group, a naphthyl group, or a phenyl group which may optionally be substituted by at least one substituent selected from the class consisting of a halogen atom, a nitro group, a lower alkyl group, a lower alkoxy group, a phenoxy group, a benzyloxy group, a lower alkylthio group, a thiocyanato group, a di-lower alkylamino group, a halogenopyridyloxy group and a methylenedioxy group, or R.sup.1 and R.sup.2, together with the carbon atom to which they are bonded, may form an aliphatic ring, said ring being optionally substituted by at least one methyl group, and their use as fungicides.
    Type: Grant
    Filed: December 2, 1983
    Date of Patent: April 8, 1986
    Assignee: Nihon Tokushu Noyaku Seizo K.K.
    Inventors: Yasuo Yamada, Junichi Saito, Toshio Gotoh, Osamu Katsumata, Shinji Sakawa
  • Patent number: 4559172
    Abstract: This invention relates to a novel acylation process which comprises using as the acylating agent an o-hydroxy-substituted aromatic oxime ester represented by the general formula (I) ##STR1## and mixing said acylating agent with an amine substance represented by the general formula (III) ##STR2## to form a compound represented by the general formula (IV) ##STR3##
    Type: Grant
    Filed: May 1, 1984
    Date of Patent: December 17, 1985
    Assignee: Nitto Boseki
    Inventors: Ikuo Hayashi, Keizo Ogihara, Tadao Itikawa, Kiyoshi Shimizu
  • Patent number: 4515616
    Abstract: Triazolyl ketone-oximes and triazolyl dioximes of the general formula I ##STR1## where Ar is an aryl radical from the group comprising biphenylyl, naphthyl and phenyl, which radical can be substituted by halogen, nitro, cyano or trifluoromethyl, by alkyl, alkoxy or alkenyl, each of not more than 5 carbon atoms or by phenoxy, andn is 1 or 2,X is oxygen or .dbd.N--OR.sup.3, R.sup.3 being hydrogen, unsubstituted, halogen-substituted or alkoxy-substituted alkyl, alkenyl or alkynyl, each of not more than 5 carbon atoms, or benzyl which is unsubstituted or substitutedby halogen, nitro, cyano or trifluoromethyl, or by alkyl or alkoxy, each of not more than 4 carbon atoms, or is --CO--R.sup.4,R.sup.4 being unsubstituted, halogen-substituted or alkoxy-substituted alkyl of not more than 5 carbon atoms, an aromatic radical or --NH--R.sup.5, R.sup.5 being alkyl or not more than 4 carbon atoms or an aromatic radical,R.sup.
    Type: Grant
    Filed: May 27, 1983
    Date of Patent: May 7, 1985
    Assignee: BASF Aktiengesellschaft
    Inventors: Costin Rentzea, Wolfgang Spiegler, Johann Jung
  • Patent number: 4497745
    Abstract: Novel oxime ethers and oxime esters of the formula I given herein have various advantageous effects with regard to stimulation of plant growth, particularly in the early stage of development of the plant. Furthermore, such compounds have the property of rendering, in the sense of an antidote action, agricultural chemicals which would otherwise damage the plants (phytotoxic chemicals) more compatible with the cultivated plants. Herbicides that are insufficiently selective can be used for example in the presence of such oxime derivatives in specific cultivated crops for combating weeds, without disadvantageous consequences for the cultivated plants.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: February 5, 1985
    Assignee: Ciba-Geigy Corporation
    Inventor: Henry Martin
  • Patent number: 4491469
    Abstract: This application discloses compounds of the formula: ##STR1## wherein R and R.sup.1 are selected from alkyl and phenyl and can form a cyclic group having 5 or 6 carbon atoms.The disclosed compounds are useful as herbicides.
    Type: Grant
    Filed: February 28, 1983
    Date of Patent: January 1, 1985
    Assignee: Velsicol Chemical Corporation
    Inventor: Leonard J. Stach
  • Patent number: 4489207
    Abstract: 2-(Hydroxyphenoxy)-carboxylates are prepared by a process wherein a dihydroxybenzene (A) is reacted with a 2-halo-fatty acid ester (B) of an alcohol, phenol or oxime of no more than 10 carbon atoms, in a molar ratio of A:B.gtoreq.1.5, in the presence of calcium hydroxide in dimethylsulfoxide, at from 0.degree. to 100.degree. C.
    Type: Grant
    Filed: December 16, 1982
    Date of Patent: December 18, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Becker, Heinz-Gunter Oeser, Rolf-Dieter Acker
  • Patent number: 4486601
    Abstract: Esters of 2-adamantanone oxime are prepared and are disclosed as possessing anti-inflammatory activity and antiviral activity against murine hepatitis virus.
    Type: Grant
    Filed: August 19, 1983
    Date of Patent: December 4, 1984
    Assignee: Pennwalt Corporation
    Inventors: C. Richard Kinsolving, Vassil St. Georgiev
  • Patent number: 4469889
    Abstract: Novel 4-phenyl-1,3-benzodiazepines, novel intermediates thereof, and methods of preparing same are described. These benzodiazepines are useful as antidepressants, analgetics and anticonvulsants.
    Type: Grant
    Filed: October 12, 1983
    Date of Patent: September 4, 1984
    Assignee: Hoechst-Roussel Pharmaceuticals, Incorporated
    Inventors: Lawrence L. Martin, Manfred Worm, Charles A. Crichlow
  • Patent number: 4460587
    Abstract: 5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines, for example compounds of the formula ##STR1## in which e.g., R.sub.1, R.sub.2 and R.sub.4 are hydrogen, R.sub.3 is methyl and C.sub.n H.sub.2n is CH.sub.2 CH.sub.2, have neuroleptic and/or antihistaminic activity. The synthesis, pharmaceutical compositions and methods of treatment utilizing such compounds are described.
    Type: Grant
    Filed: November 29, 1982
    Date of Patent: July 17, 1984
    Assignee: Ciba-Geigy Corporation
    Inventor: Isidoros Vlattas
  • Patent number: 4386954
    Abstract: This invention is directed to diphenyl ethers having in the 3' position a radical of the formula: ##STR1## The products are prepared by reacting a 3'-halocarbonyl compound with an appropriately substituted oxime. These compounds and their agronomically acceptable salts and compositions containing these compounds as active ingredients are selective herbicides.
    Type: Grant
    Filed: August 17, 1981
    Date of Patent: June 7, 1983
    Assignee: Rohm and Haas Company
    Inventors: John W. Ashmore, Ted T. Fujimoto
  • Patent number: 4380661
    Abstract: 2-[p-(p-substituted phenoxy)phenoxy]propionyl oximes, processes for their preparation, herbicidal compositions containing these oximes and methods of use of the herbicidal compositions are disclosed.
    Type: Grant
    Filed: February 23, 1981
    Date of Patent: April 19, 1983
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Milos Suchy
  • Patent number: 4365991
    Abstract: Propionic acid oximes of the general formula ##STR1## wherein R.sub.1 is hydrogen, alkyl of from 1 to 6 carbon atoms or cycloalkyl of from 3 to 6 carbon atoms, R.sub.2 is hydrogen, alkyl of from 1 to 6 carbon atoms, alkenyl of from 2 to 6 carbon atoms or alkynyl of from 2 to 6 carbon atoms, or R.sub.1 and R.sub.2 together with the carbon atom to which they are attached form a cyclopentane or cyclohexane ring which can be mono-, di- or trisubstituted with alkyl of from 1 to 3 carbon atoms, R.sub.3 is hydrogen, halogen or nitro with the proviso that R.sub.1 and R.sub.2 are not simultaneously hydrogen, processes for their manufacture, herbicidal compositions containing these compounds as the active ingredient and methods of use of the herbicidal compositions are disclosed.
    Type: Grant
    Filed: March 6, 1981
    Date of Patent: December 28, 1982
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Wijitha de Silva
  • Patent number: 4344953
    Abstract: Substituted alkanyl-azolyl oxime-carbamates of the formula ##STR1## in which Az represents an optionally substituted azolyl radical,R.sup.1 represents hydrogen or alkyl,R.sup.2 represents hydrogen, alkyl, alkenyl, alkynyl, halogenoalkyl, halogenoalkenyl or alkoxyalkyl, or, provided R.sup.1 represents alkyl, R.sup.2 may represent the --(S).sub.m --R.sup.3 group,R.sup.3 represents alkyl, halogenoalkyl, optionally substituted phenyl, alkoxycarbonyl, the --NR.sup.4 R.sup.5 group or a radical identical to that to which the --(S).sub.n --R.sup.3 group is bonded,R.sup.4 represents alkyl,R.sup.5 represents alkyl, dialkylcarbamoyl, alkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl or optionally substituted phenylsulphonyl, orR.sup.4 and R.sup.
    Type: Grant
    Filed: August 29, 1980
    Date of Patent: August 17, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jorg Stetter, Bernhard Homeyer, Ingeborg Hammann
  • Patent number: 4273785
    Abstract: Novel 4-monoalkylamino-benzaldehydes, 4-mono-alkylamino-alkanophenones, and 4-monoalkylamino-benzophenones, and derivatives and salts thereof, are disclosed which are useful as anti-atherosclerotic agents.
    Type: Grant
    Filed: September 27, 1977
    Date of Patent: June 16, 1981
    Assignee: American Cyanamid Company
    Inventor: Robert G. Shepherd