O-ethers (i.e., H Of Oxime -oh Replaced By Ether Forming Group) Patents (Class 564/256)
  • Patent number: 4388469
    Abstract: Diphenylalkanoether and diphenylalkanone oxime-ether derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are each independently an aryl group optionally substituted with 1 to 3 substituents selected from the group consisting of halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, nitro, cyano, di(C.sub.1 -C.sub.4)alkylamino, amino, benzyloxy, hydroxyl, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfinyl, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 alkanoylamino, C.sub.1 -C.sub.4 alkylamino and N-(C.sub.1 -C.sub.4)alkyl-N-(C.sub.1 -C.sub.4)alkanoylamino, Z.sup.1 is a group of the formula: ##STR2## (wherein R.sup.3 and R.sup.4 are each independently a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group or an ar(C.sub.1 -C.sub.
    Type: Grant
    Filed: April 2, 1980
    Date of Patent: June 14, 1983
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Keiichi Ono, Hajime Kawakami, Junki Katsube
  • Patent number: 4384141
    Abstract: .alpha.-Bromoacetophenone-oxime-ethers are prepared by reacting acetophenone-oxime-ethers with a brominating agent at from 20.degree. to 100.degree. C., in the absence of light.The .alpha.-bromoacetophenone-oxime-ethers obtained are valuable starting materials for the preparation of drugs, dyes and pesticides.
    Type: Grant
    Filed: November 5, 1981
    Date of Patent: May 17, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter Schaefer, Dietrich Mangold
  • Patent number: 4375981
    Abstract: Disclosed are compounds such as 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitroacetophenone oxime-O-methyl ether, and the method of controlling weeds, such as wild oats with the compounds.
    Type: Grant
    Filed: November 21, 1980
    Date of Patent: March 8, 1983
    Assignee: PPG Industries, Inc.
    Inventor: Dennis K. Krass
  • Patent number: 4351956
    Abstract: Compounds of the formula: ##STR1## wherein R and R.sup.1 are alkyl C.sub.1 -C.sub.4 are useful as color formers for pressure- and heat-sensitive copying materials.
    Type: Grant
    Filed: August 31, 1981
    Date of Patent: September 28, 1982
    Assignee: American Cyanamid Company
    Inventors: Frank F. Cesark, Daniel W. Thomas
  • Patent number: 4342763
    Abstract: Derivatives of p-chloroacetophenone oxime, the preparation thereof and the use thereof as medicaments.The compounds of the invention correspond to the general formula I ##STR1## wherein R.sub.1 and R.sub.2 each represent a lower alkyl radical, preferably a C.sub.1 to C.sub.4 radical, or, in association with the nitrogen atom to which they are linked, form a saturated heterocyclic group, and the physiologically acceptable acid addition salts.The compounds of the invention are useful as medicaments and particularly as analgesics, antipyretics, anti-inflammatory agents and antitussives.
    Type: Grant
    Filed: February 6, 1980
    Date of Patent: August 3, 1982
    Assignee: Provesan S.A.
    Inventor: Jose Esteve Soler
  • Patent number: 4308399
    Abstract: A compound effective in the treatment of diabetic angiopathy, i.e. a selective .beta.-receptor blocker has the formula ##STR1## wherein: R.sup.2 is a hydrogen or alkyl having one to five carbon atoms,R.sup.3 is alkyl having one to five carbon atoms, cycloalkyl or phenyl optionally substituted with hydroxyl or phenyl, or R.sup.2 and R.sup.3 together form a five- to eight-membered ring optionally containing also other heteroatoms and/or fused with another ring, preferably phenyl, naphthyl, quinolyl, isoquinolyl, pyridyl, pyrazolyl,R.sup.5 is hydrogen or alkyl having one to four carbon atoms, cycloalkyl or phenyl optionally substituted with halogen, alkoxy having one to four carbon atoms or alkyl having one to four carbons,R.sup.6 is hydrogen, alkyl having one to four carbon atoms or phenyl, m=0, 1 or 2, and n=0, 1 or 2.
    Type: Grant
    Filed: July 5, 1979
    Date of Patent: December 29, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Kalman Takacs, Peter N. Literati, Ilona Kiss nee Ajzert, Antal Simay, Matyas Szentivanyi, Sandor Virag, Katalin Farago
  • Patent number: 4293715
    Abstract: In the preparation of an .omega.-azolyl-acetophenone oxime ether of the formula ##STR1## in which R is halogen, alkyl, alkoxy, alkylthio, alkylsulphonyl, halogenoalkyl, nitro, cyano, optionally substituted phenyl or optionally substituted phenoxy,R' is alkyl, alkenyl, alkynyl, optionally substituted cycloalkylalkyl, optionally substituted aralkyl or optionally substituted aralkenyl,n is 1, 2 or 3,Hal is halogen, andZ is CH or N,wherein the .omega.-halogen of an .omega.-halogeno-acetophenone of the formula ##STR2## is replaced by an azole of the formula ##STR3## and the keto oxygen is replaced by.dbd.N--O--R.sup.1,the improvement which comprises first reacting the .omega.-halogeno-acetophenone with a hydroxylamine ether of the formulaH.sub.2 N--O--R'to produce an .omega.-halogeno-acetophenone oxime ether of the formula ##STR4## and reacting the acetophenone oxime ether with the azole, thereby to obtain the desired product in enhanced yield. The intermediate acetophenone oxime ethers are new.
    Type: Grant
    Filed: February 11, 1980
    Date of Patent: October 6, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventor: Wolfgang Kramer
  • Patent number: 4289526
    Abstract: This invention relates to imidazole and triazole compounds useful as fungicides, herbicides and plant growth regulators; to a process for preparing them; to compositions containing them; and to methods of using them to combat fungal infections in plants and to control the growth of vegetation.
    Type: Grant
    Filed: June 20, 1980
    Date of Patent: September 15, 1981
    Assignee: Imperial Chemical Industries Limited
    Inventors: Paul A. Worthington, Paul de Fraine, William G. Rathmell, Diana M. Gatehouse
  • Patent number: 4285942
    Abstract: The invention relates to novel cyclododecane derivatives of the general formula ##STR1## wherein R.sup.1 and R.sup.2 represent independently from each other a hydrogen atom, a C.sub.1-6 alkyl group or a C.sub.3-8 cycloalkyl group, or R.sup.1 and R.sup.2 form together with the nitrogen atom to which they are attached a heterocyclic ring containing 4 to 7 carbon atoms and optionally a further heteroatom selected from the group consisting of oxygen, sulphur and nitrogen, said ring may be optionally substituted by a C.sub.1-3 alkyl or benzyl group; and A represents a C.sub.2-6 straight or branched alkylene chain, and optically active isomers, acid addition salts and quaternary ammonium derivatives thereof. The invention relates further to an analogous process for the preparation of said compounds, to pharmaceutical compositions containing said compounds as the active ingredient and to a process for the preparation of said pharmaceutical compositions.
    Type: Grant
    Filed: December 3, 1979
    Date of Patent: August 25, 1981
    Assignee: Egyt Gyogyszervegyeszeti Gyar
    Inventors: Zoltan Budai, Aranka Lay nee Konya, Tibor Mezei, Katalin Grasser, Lujza Petocz, Eniko Kiszelly, Ibolya Kosoczky
  • Patent number: 4283406
    Abstract: A method of combating Botrytis fungi, comprising applying to such fungi, or to a habitat thereof to be protected against such fungus a fungicidally effective amount of a 1-(2,4-dichlorophenyl)-1-(2,6-dihalogenobenzyloximino)-2-(1,2,4-triazol-1- yl)-ethane of the formula ##STR1## in which X and Y each independently is halogen or a physiologically acceptable acid addition salt thereof. Those compounds in which X is chlorine or fluorine and Y is fluorine are new.
    Type: Grant
    Filed: April 21, 1980
    Date of Patent: August 11, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Hans-Joachim Knops, Karl H. Buchel, Wilhelm Brandes
  • Patent number: 4273785
    Abstract: Novel 4-monoalkylamino-benzaldehydes, 4-mono-alkylamino-alkanophenones, and 4-monoalkylamino-benzophenones, and derivatives and salts thereof, are disclosed which are useful as anti-atherosclerotic agents.
    Type: Grant
    Filed: September 27, 1977
    Date of Patent: June 16, 1981
    Assignee: American Cyanamid Company
    Inventor: Robert G. Shepherd
  • Patent number: 4267334
    Abstract: The invention concerns 6-methoxy-2-acetylnaphthalene oxime derivatives of the general formula ##STR1## in which R.sub.1 and R.sub.2 each represent a lower alkyl radical, or form, in association with the nitrogen atom to which they are linked, a saturated heterocyclic group, and the acid addition salts thereof with physiologically acceptable acids. These derivatives have analgesic, antipyretic and anti-inflammatory activity and can be made up into pharmaceutical compositions in tablet, capsule, suppository and the like forms. The derivatives of the invention may be prepared by reacting the corresponding 2-acetyl-6-methoxynaphthalene oximes with an appropriate substituted halogeno-ethylamine.
    Type: Grant
    Filed: July 20, 1979
    Date of Patent: May 12, 1981
    Assignee: Productos Esteve Internacional S.A.
    Inventor: Antonio Esteve Subirana
  • Patent number: 4263227
    Abstract: Disclosed are compounds such as 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitroacetophenone oxime-O-methyl ether, and the method of controlling weeds, such as wild oats with the compounds.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: April 21, 1981
    Assignee: PPG Industries, Inc.
    Inventor: Dennis K. Krass
  • Patent number: RE30634
    Abstract: Insecticidal benzyl oxime ethers of the formula: ##STR1## wherein the symbols have meanings defined in the specification.
    Type: Grant
    Filed: August 27, 1979
    Date of Patent: June 2, 1981
    Assignee: Shell Oil Company
    Inventor: Arthur C. Henry