Six-membered Alicyclic Ring Double Bonded Directly To The Oxime Nitrogen Patents (Class 564/267)
  • Patent number: 10041913
    Abstract: Provided is a system comprising a conduit from a gas chromatograph column to a reactor comprising a Ru catalyst, with a hydrogen feed conduit for providing hydrogen to the conduit from the gas chromatograph column, and a conduit from the reactor to an FID detector. This allows one to practice a method for the detection and quantification of organic molecules from a gas chromatograph which comprises passing the effluent from a gas chromatograph column to a reactor comprising a Ru catalyst; adding hydrogen to the effluent prior to the effluent reaching the catalyst; reacting the effluent from the gas chromatograph column in the reactor to reduce all organic containing molecules to CH4 by heating to an elevated temperature, and passing the effluent from the reactor to an FID.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: August 7, 2018
    Assignee: Activated Research Company, LLC
    Inventor: Andrew Jones
  • Patent number: 9926453
    Abstract: A method for coating a surface comprises applying a layer of coating composition onto the surface, mechanically forming parallel ribs on the layer, and simultaneously polymerizing the layer with ultraviolet radiations. The coating composition comprises a mass percentage of urethan-acrylate oligomer, with an average molar mass in number between 1000 and 5000 g·mol?1, between 35% and 75%. The coating composition further comprises a mass percentage of a diluting agent, copolymerizable with urethan-acrylate oligomers, between 15% and 60%, and a mass percentage of pyrogenic silica between 0.5% and 5%.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: March 27, 2018
    Assignees: AIRBUS, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
    Inventors: Elisa Campazzi, Jocelyne Galy, Franck Gaudin, Jean-François Gerard, Martine Villatte
  • Patent number: 9371238
    Abstract: The present invention provides a titanium-silicalite molecular sieve and a method for preparing the same. The method includes the steps of preparing a mixture of a titanium source, a silicon source, a transition metal source, a template agent and water; heating the mixture to form a gel mixture; heating the gel mixture in a water bath; and calcining the gel mixture after the gel mixture in the water bath to form the titanium-silicalite molecular sieve. The present invention further provides a method for preparing cyclohexanone oxime by using the titanium-silicalite molecular sieve as the catalyst which results in high conversion rate, high selectivity and high usage efficiency of hydrogen peroxide.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: June 21, 2016
    Assignee: China Petrochemical Development Corporation
    Inventors: Ya-Ping Chen, Cheng-Fa Hsieh, Pin-To Yao, Chien-Chang Chiang
  • Patent number: 8932980
    Abstract: The invention discloses three-dimensional, ordered, mesoporous titanosilicates wherein the Ti is in a tetrahedral geometry and exclusively substituted for Si in the silica framework. Such titanosilicates find use as catalysts for epoxidation, hydroxylation, C—H bond oxidation, oxidation of sulfides, aminolysis of epoxide and amoximation, with approx. 100% selectivity towards the products.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: January 13, 2015
    Assignee: Council of Scientific & Industrial Research
    Inventors: Srinivas Darbha, Anuj Kumar
  • Publication number: 20140364622
    Abstract: The present invention relates to a process for the enantioselective preparation of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid ((1S,4R)-9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide of formula Ib.
    Type: Application
    Filed: February 13, 2013
    Publication date: December 11, 2014
    Applicant: SYNGENTA PARTICIPATIONS AG
    Inventor: Tomas Smejkal
  • Patent number: 8779125
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: July 15, 2014
    Assignee: University of Southampton
    Inventors: Robert Raja, John Meurig Thomas
  • Patent number: 8779124
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: July 15, 2014
    Assignee: University of Southampton
    Inventors: Robert Raja, Alexander James Patterson
  • Patent number: 8772194
    Abstract: The present invention provides a method for preparing a large-sized titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve. The method for preparing a large-sized titanium-silicalite molecular sieve includes preparing a mixture of a titanium source, a silicon source and a template agent; heating the mixture to form a gel mixture; mixing a colloidal silica with the gel mixture; heating the gel mixture mixed with the colloidal silica in a water bath; and calcining the gel mixture mixed with the colloidal silica. In the present invention, the average particle size of the large-sized titanium-silicalitem molecular sieve is more than 10 um, and the particle size distribution is centralized, so as to avoid the formation of titanium-oxygen-titanium bonding. The method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve results in high conversion rate, high selectivity and easy recovery.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: July 8, 2014
    Assignee: China Petrochemical Development Corporation, Taipei (Taiwan)
    Inventors: Shih-Yao Chao, Cheng-Fa Hsieh, Chien-Chang Chiang, Ya-Ping Chen, Pin-To Yao
  • Patent number: 8753998
    Abstract: The present invention provides a method for preparing a titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the titanium-silicalite molecular sieve. The method for preparing a titanium-silicalite molecular sieve includes the steps of preparing a mixture of a titanium source, a silicon source and a template agent, wherein the titanium source has a structure of formula (I); heating the mixture to form a gel mixture; mixing the gel mixture with water; heating the gel mixture mixed with the water in a water bath; and calcining the gel mixture mixed with the water. The method using the titanium-silicalite molecular sieve for preparing cyclohexanone oxime results in high conversion rate and high selectivity.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: June 17, 2014
    Assignee: China Petrochemical Development Corporation, Taipei (Taiwan)
    Inventors: Chien-Chang Chiang, Cheng-Fa Hsieh, Pin-To Yao, Shih-Yao Chao
  • Publication number: 20140148569
    Abstract: In a process for oxidizing a feed comprising cyclohexylbenzene, the feed is contacted with oxygen and an oxidation catalyst in a plurality of reaction zones connected in series, the contacting being conducted under conditions being effective to oxidize part of the cyclohexylbenzene in the feed to cyclohexylbenzene hydroperoxide in each reaction zone. At least one of the plurality of reaction zones has a reaction condition that is different from another of the plurality of reaction zones. The different reaction conditions may include one or more of (a) a progressively decreasing temperature and (b) a progressively increasing oxidation catalyst concentration as the feed flows from one reaction zone to subsequent reaction zones in the series.
    Type: Application
    Filed: August 16, 2011
    Publication date: May 29, 2014
    Applicant: ExxonMobil Chemical Patents Inc.
    Inventors: Jihad Mohammed Dakka, Francisco Manuel Benitez, Bryan Amrutlal Patel, Edmund John Mozeleski
  • Publication number: 20130245322
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms.
    Type: Application
    Filed: May 8, 2013
    Publication date: September 19, 2013
    Applicant: University of Southampton
    Inventors: Robert Raja, Alexander James Patterson
  • Publication number: 20130245323
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms.
    Type: Application
    Filed: May 8, 2013
    Publication date: September 19, 2013
    Applicant: University of Southampton
    Inventors: Robert Raja, John Meuring THOMAS
  • Patent number: 8507694
    Abstract: The invention relates to a process for the preparation of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: August 13, 2013
    Assignee: Syngenta Crop Protection LLC
    Inventors: Denis Gribkov, Adrian Müller, Martin Lager, Fanny Giordano
  • Publication number: 20130172514
    Abstract: In a process for producing a cycloalkylaromatic compound, an aromatic compound, hydrogen and at least one diluent are supplied to a hydroalkylation reaction zone, such that the weight ratio of the diluent to the aromatic compound supplied to the hydroalkylation reaction zone is at least 1:100. The aromatic compound, hydrogen and the at least one diluent are then contacted under hydroalkylation conditions with a hydroalkylation catalyst in the hydroalkylation reaction zone to produce an effluent comprising a cycloalkylaromatic compound.
    Type: Application
    Filed: June 28, 2011
    Publication date: July 4, 2013
    Applicant: ExxonMobil Chemical Patents Inc.
    Inventors: Teng Xu, Wenyih F. Lai
  • Patent number: 8450526
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: May 28, 2013
    Assignee: University of Southhampton
    Inventors: Robert Raja, John Meurig Thomas
  • Patent number: 8444917
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: May 21, 2013
    Assignee: University of Southampton
    Inventors: Robert Raja, Alexander James Paterson
  • Publication number: 20130116453
    Abstract: The invention discloses three-dimensional, ordered, mesoporous titanosilicates wherein the Ti is in a tetrahedral geometry and exclusively substituted for Si in the silica framework. Such titanosilicates find use as catalysts for epoxidation, hydroxylation, C—H bond oxidation, oxidation of sulfides, aminolysis of epoxide and amoximation, with approx. 100% selectivity towards the products.
    Type: Application
    Filed: July 20, 2011
    Publication date: May 9, 2013
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Srinivas Darbha, Anuj Kumar
  • Publication number: 20130041181
    Abstract: The present invention provides a titanium-silicalite molecular sieve and a method for preparing the same. The method includes the steps of preparing a mixture of a titanium source, a silicon source, a metal source selected from IIA to IVA elements and a template agent; heating the mixture to form a gel mixture; heating the gel mixture in a water bath; and calcining the gel mixture after the gel mixture in the water bath to form the titanium-silicalite molecular sieve. The present invention further provides a method for preparing cyclohexanone oxime by using the titanium-silicalite molecular sieve as the catalyst which results in high conversion rate, high selectivity and high usage efficiency of hydrogen peroxide.
    Type: Application
    Filed: January 13, 2012
    Publication date: February 14, 2013
    Applicant: China Petrochemical Development Corporation
    Inventors: Ya-Ping Chen, Cheng-Fa Hsieh, Pin-To Yao, Chien-Chang Chiang
  • Publication number: 20120277468
    Abstract: The present invention provides a titanium-silicalite molecular sieve and a method for preparing the same. The method includes the steps of preparing a mixture of a titanium source, a silicon source, a transition metal source, a template agent and water; heating the mixture to form a gel mixture; heating the gel mixture in a water bath; and calcining the gel mixture after the gel mixture in the water bath to form the titanium-silicalite molecular sieve. The present invention further provides a method for preparing cyclohexanone oxime by using the titanium-silicalite molecular sieve as the catalyst which results in high conversion rate, high selectivity and high usage efficiency of hydrogen peroxide.
    Type: Application
    Filed: January 6, 2012
    Publication date: November 1, 2012
    Applicant: China Petrochemical Development Corporation, Taipei (Taiwan)
    Inventors: Ya-Ping Chen, Cheng-Fa Hsieh, Pin-To Yao, Chien-Chang Chiang
  • Publication number: 20120271066
    Abstract: The present invention provides a method for preparing a titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the titanium-silicalite molecular sieve. The method for preparing a titanium-silicalite molecular sieve includes the steps of preparing a mixture of a titanium source, a silicon source and a template agent, wherein the titanium source has a structure of formula (I); heating the mixture to form a gel mixture; mixing the gel mixture with water; heating the gel mixture mixed with the water in a water bathe; and calcining the gel mixture mixed with the water. The method using the titanium-silicalite molecular sieve for preparing cyclohexanone oxime results in high conversion rate and high selectivity.
    Type: Application
    Filed: January 6, 2012
    Publication date: October 25, 2012
    Applicant: China Petrochemical Development Corporation, Taipei (Taiwan)
    Inventors: Chien-Chang Chiang, Cheng-Fa Hsieh, Pin-To Yao, Shih-Yao Chao
  • Publication number: 20120253073
    Abstract: There is provided a method for producing an oxime compound, which is characterized by the steps of: (a) oxidizing cumene to produce cumene hydroperoxide, (b) subjecting the cumene hydroperoxide to an ammoximation reaction with ammonia and a ketone in the presence of a catalyst to produce a reaction mixture containing an oxime compound corresponding to the ketone and 2-phenyl-2-propanol, (c) separating a fraction of 2-phenyl-2-propanol and the oxime compound corresponding to the ketone from the reaction mixture resulting in the step (b), (d) converting 2-phneyl-2-propanol in the fraction to cumene, and (e) recycling at least a portion of the cumene resulting in step(d) to step (a).
    Type: Application
    Filed: March 22, 2012
    Publication date: October 4, 2012
    Inventors: Sho TSUJIUCHI, Masami Fukao
  • Publication number: 20120209029
    Abstract: The present invention provides a method for preparing a large-sized titanium-silicalite molecular sieve, and a method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve. The method for preparing a large-sized titanium-silicalite molecular sieve includes preparing a mixture of a titanium source, a silicon source and a template agent; heating the mixture to form a gel mixture; mixing a colloidal silica with the gel mixture; heating the gel mixture mixed with the colloidal silica in a water bathe; and calcining the gel mixture mixed with the colloidal silica. In the present invention, the average particle size of the large-sized titanium-silicalite molecular sieve is more than 10 um, and the particle size distribution is centralized, so as to avoid the formation of titanium-oxygen-titanium bonding. The method for preparing cyclohexanone oxime using the large-sized titanium-silicalite molecular sieve results in high conversion rate, high selectivity and easy recovery.
    Type: Application
    Filed: January 6, 2012
    Publication date: August 16, 2012
    Applicant: China Petrochemical Development Corporation, Taipei (Taiwan)
    Inventors: Shih-Yao CHAO, Cheng-Fa HSIEH, Chien-Chang CHIANG, Ya-Ping CHEN, Pin-To YAO
  • Publication number: 20120136162
    Abstract: The invention relates to a process for the preparation of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide.
    Type: Application
    Filed: July 7, 2010
    Publication date: May 31, 2012
    Applicant: SYNGENTA CROP PROTECTION, LLC
    Inventors: Denis Gribkov, Adrian Müller, Martin Lager, Fanny Giordano
  • Publication number: 20120078014
    Abstract: To produce cyclohexanone oxime stably for a long time by an ammoximation reaction of cyclohexanone. Cyclohexanone oxime is produced by performing an ammoximation reaction of cyclohexanone with hydrogen peroxide and ammonia in the presence of titanosilicate and a solid containing a silicon compound, wherein the solid containing a silicon compound is one that had been used in a Beckmann rearrangement reaction of cyclohexanone oxime as a catalyst.
    Type: Application
    Filed: September 22, 2011
    Publication date: March 29, 2012
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Masami FUKAO, Hiroshi TOMOI
  • Publication number: 20120016161
    Abstract: The present invention provides a method for producing an oxime, comprising the step of an ammoximation reaction of a ketone with an organic peroxide and ammonia in the presence of a catalyst containing titanium and silicon oxide, wherein the catalyst containing titanium and a silicon oxide is a mesoporous silicate, and is subjected to a contact treatment with a silicon compound.
    Type: Application
    Filed: July 13, 2011
    Publication date: January 19, 2012
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventor: Sho TSUJIUCHI
  • Publication number: 20110293553
    Abstract: Compounds, compositions, kits, devices, and methods of attracting, detecting, eradicating, controlling, or killing an insect, such as a bed bug, by utilizing insect attractant, arresting, and/or aggregation compounds and compositions is provided. Insect attractant, arresting, and/or aggregation compounds identified from insect fecal extract by an analytical technique, such as gas chromatography, nuclear magnetic resonance (NMR), Carbon-13 NMR, mass spectroscopy, LC-MS, GC-MS, high performance liquid chromatography (HPLC), or combinations thereof are provided. A bed bug attractant, arresting, and/or aggregation compound identified from bed bug feces and exhibiting a Carbon-13 NMR peak at about ? 159.453 ppm is also provided.
    Type: Application
    Filed: May 28, 2010
    Publication date: December 1, 2011
    Inventors: Tai-Teh Wu, Kenneth Haynes, Joe Harold Hope, III
  • Patent number: 8058475
    Abstract: Novel cyclohexylmethyl compounds corresponding to formula I wherein R1, R2, R3, R4 and R5, have the meanings given in the description. Pharmaceutical formulations containing these compounds, as well as a processes for preparing these compounds and related methods of treatment are also provided.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: November 15, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Stefan Oberboersch, Beatrix Merla, Bernd Sundermann, Werner Englberger, Hagen-Heinrich Hennies, Achim Kless, Petra Bloms-Funke, Babette-Yvonne Koegel, Heinze Graubaum
  • Publication number: 20110275680
    Abstract: The invention relates to novel chemical compounds, in particular oxime derivatives of 3,5-seco-4-nor-cholestane, to the application thereof as drugs, in particular cytoprotective drugs, and more particularly as neuroprotective, cardioprotective and/or hepatoprotective drugs.
    Type: Application
    Filed: December 17, 2009
    Publication date: November 10, 2011
    Applicant: TROPHOS
    Inventors: Cyrille Drouot, Abdesslame Nazih, Corinne Chaimbault
  • Publication number: 20110257390
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M2AlPO-5 (I) in which M1 is at least one transition metal atom having redox catalytic capability; M2 is at least one metal atom in the (IV) oxidation state; M1 and M2 are different from each other; and a proportion of the phosphorous atoms in the M1M2AlPO-5 type structure are replaced by M2 atoms.
    Type: Application
    Filed: January 6, 2010
    Publication date: October 20, 2011
    Applicant: UNIVERSITY OF SOUTHAMPTON
    Inventors: Robert Raja, Alexander James Paterson
  • Patent number: 8003825
    Abstract: The present invention provides a process for producing a cycloalkanone oxime by conducting a continuous ammoximation reaction in the presence of a titanosilicate catalyst with supplying a cycloalkanone, hydrogen peroxide, ammonia and an organic solvent into the reaction system, wherein the reaction temperature is from 90° C. to 120° C. and the supplying amount of the organic solvent is not more than 2 times by weight of that of the cycloalkanone.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: August 23, 2011
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Masami Fukao, Miyuki Oikawa
  • Patent number: 7884246
    Abstract: Disclosed is a process for preparing substituted anisidines of formula I starting from substituted cyclic hydroxy-ketones II via aromatization through a substituted oxime intermediate IV in which R is C1-C6 alkyl or halogen, and Alk is C1-C6 alkyl. The substituted anisidines of formula I have been found to be useful as intermediates in the preparation of agents for the treatment of hepatitis C viral (HCV) infections.
    Type: Grant
    Filed: November 1, 2006
    Date of Patent: February 8, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Fabrice Gallou, Heewon Lee, Chris Hugh Senanayake, Jinhua J. Song, Zhulin Tan, Jinghua Xu, Nathan K. Yee
  • Publication number: 20100331576
    Abstract: The invention relates to a new process which allows the preparation of TS-1 zeolites in a pure phase and with a crystallinity higher than 95%, operating at reduced reaction volumes, and obtaining high productivities and extremely high crystallization yields. The particular crystalline form of the TS-1 zeolite thus prepared, is also described.
    Type: Application
    Filed: December 3, 2008
    Publication date: December 30, 2010
    Applicant: POLIMERI EUROPA S.P.A.
    Inventors: Angela Carati, Donatella Berti, Roberto Millini, Franco Rivetti, Angela Maria Mantegazza, Gianni Girotti
  • Publication number: 20100324335
    Abstract: An object of the present invention is to produce an oxime with a satisfactory yield by an ammoximation reaction of a ketone with a peroxide and ammonia. Disclosed is a process for producing oxime, which comprises conducting an ammoximation reaction of a ketone with a peroxide and ammonia in the presence of a mesoporous titanosilicate. The peroxide is preferably an organic peroxide. The mesoporous titanosilicate is preferably a HMS type or MCM-41 type mesoporous titanosilicate. The ketone is preferably cycloalkanone.
    Type: Application
    Filed: June 17, 2010
    Publication date: December 23, 2010
    Inventors: Sho Tsujiuchi, Nobufumi Watanabe
  • Publication number: 20100273801
    Abstract: The invention relates to compouns derived from betulin, and to the use thereof as antibacterial agents in pharmaceutical and cosmetic applications.
    Type: Application
    Filed: June 6, 2007
    Publication date: October 28, 2010
    Applicant: Valition teknillinen tutikimuskeskus
    Inventors: Jari Yli-Kauhaluoma, Salme Koskimies, Sami Alakurtti, Taru Mäkelä, Päivi Tammela
  • Publication number: 20100179317
    Abstract: A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst; wherein the catalyst is an aluminophosphate based redox catalyst having at least two different redox catalytic sites comprising different transition metal atoms.
    Type: Application
    Filed: July 2, 2008
    Publication date: July 15, 2010
    Applicant: University of Southampton
    Inventor: Robert RAJA
  • Publication number: 20100069670
    Abstract: An oxidation catalyst for use in the oxidation of a substrate with a molecular oxygen, comprising at least one member selected from the group consisting of a specific hydrazyl radical (such as 2,2-diphenyl-1-picrylhydrazyl) and a specific hydrazine compound (such as 2,2-diphenyl-1-picrylhydrazine). A method for producing a chemical compound, comprising contacting a substrate with a molecular oxygen in the presence of the above-mentioned oxidation catalyst.
    Type: Application
    Filed: November 13, 2009
    Publication date: March 18, 2010
    Applicant: ASAHI KASEI CHEMICALS CORPORATION
    Inventor: Ken Suzuki
  • Patent number: 7608738
    Abstract: The present invention relates to a process for the coammoximation, that is to say for the simultaneous ammoximation, of ketones, in particular of cyclic ketones such as cyclododecanone and cyclohexanone. Ammoximation is taken to mean here the preparation of oximes from ketones or aldehydes together with hydrogen peroxide and ammonia and in the presence of a catalyst which essentially consists of silicon, titanium and oxygen, for example titanium silicalite.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: October 27, 2009
    Assignee: Degussa AG
    Inventors: Juergen Herwig, Martin Roos, Georg Oenbrink, Bernd Guenzel, Dirk Kuppert
  • Patent number: 7537745
    Abstract: The invention relates to a process for mixing a first acidic aqueous solution comprising hydroxylammonium and phosphate with a second acidic aqueous solution comprising nitric acid at a temperature between 20 and 80° C. resulting in a third acidic aqueous solution comprising hydroxylammonium, phosphate and nitric acid, wherein in the third acidic aqueous solution the total acid concentration minus the phosphate concentration is lower than 0.523*In([hydroxylammonium]/1.25)+422/(T+81) whereby [hydroxylammonium] is the concentration of hydroxylammonium in the third acidic aqueous solution, T is the temperature of the third acidic aqueous solution expressed in ° C. and all concentrations are expressed in mol/l.
    Type: Grant
    Filed: December 10, 2003
    Date of Patent: May 26, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Hendrik Oevering, Arno H Benneker
  • Patent number: 7449600
    Abstract: A process for producing cyclohexanone oxime is provided: (1) reacting cyclohexanone, hydrogen peroxide and ammonia in the presence of a titanosilicate catalyst to give a reaction solution containing cyclohexanone oxime, water, unreacted ammonia and unreacted cyclohexanone, (2) distilling off ammonia, (3) an extraction step, (4) mixing the organic layer obtained in step (3) with water followed by separating into an organic and aqueous layers, (5) distilling off organic solvent and water to obtain a bottom product containing cyclohexanone oxime and cyclohexanone, and (6) distilling off cyclohexanone and to obtain a bottom product containing cyclohexanone oxime; wherein a compound selected from an oxide, an oxo acid, an oxo acid salt, an oxo acid ester and an oxo acid amide of boron or phosphorous is added to at least one of the water used in the step (4) and the organic layer obtained in step (4) to be subjected to step (5).
    Type: Grant
    Filed: February 24, 2006
    Date of Patent: November 11, 2008
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Masami Fukao, Shinichi Kawase
  • Publication number: 20080275130
    Abstract: The invention relates to compounds of formula (I): where X+Y=keto, or X=OH and Y=H, or X+Y=oxime or methyloxime, B=OH and C+D=H, or C+D=C1-C4 linear or branched alkyl, or C=H and D=C1-C4 linear or branched alkyl, or B+C=keto and D=methyl, hydroxyl, or methylamino, or B and C=H and D=methylamino, or B+C=oxime and D=methyl and R=C1-C10 linear or branched alkyl, the salts, esters, or salts of esters thereof as medicament, in particular as neuroprotectors, novel compounds of formula (I) and pharmaceutical compositions.
    Type: Application
    Filed: August 19, 2005
    Publication date: November 6, 2008
    Inventors: Thierry Bordet, Cyrille Drouot
  • Patent number: 7423178
    Abstract: The invention relates to a process for treating an organic solution comprising cyclohexanone oxime, cyclohexanone and an organic solvent, said process comprising distilling the organic solution such as to obtain (i) a first product comprising organic solvent, (ii) a second product comprising cyclohexanone and (iii) a third product comprising cyclohexanone oxime; and feeding the second product to a cyclohexanone oxime synthesis zone in which hydroxylammonium is reacted with cyclohexanone to form cyclohexanone oxime.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: September 9, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Hendrik Oevering, Arno H Benneker, Johannes A L Brouwers
  • Patent number: 7408081
    Abstract: The invention relates to a process for treating an aqueous medium containing cyclohexanone oxime and cyclohexanone, said process comprising stripping the aqueous medium with steam, wherein said stripping is carried out at a pressure higher than 0.11 MPa. The invention also relates to a process for the preparation of cyclohexanone oxime, which involves stripping at a pressure higher than 0.11 MPa.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: August 5, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Arno Benneker, Henk Oevering, Johannes A. L. Brouwers
  • Patent number: 7091381
    Abstract: A method for producing cyclohexanone oxime, which comprises the steps of (1) subjecting to an amination reaction a starting material selected from the group consisting of cyclohexanol, cyclohexanone and a mixture thereof, thereby obtaining cyclohexylamine, and (2) subjecting the obtained cyclohexylamine to a partial oxidation reaction, thereby obtaining cyclohexanone oxime, wherein a by-product (?) formed in the step (1) and/or a by-product (?) formed in the step (2) are/is recycled to a reaction system of the amination reaction in the step (1).
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: August 15, 2006
    Assignee: Asahi Kasei Chemicals Corporation
    Inventors: Ken Suzuki, Hajime Nagahara
  • Patent number: 7087599
    Abstract: The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynacomastia, vascular smooth muscle cell proliferation, obesity, incontinence, and cancer, in particular of the breast, uterus and prostate.
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: August 8, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Dann LeRoy Parker, Jr., Ronald W. Ratcliffe, Robert R. Wilkening, Kenneth J. Wildonger
  • Patent number: 7067699
    Abstract: In producing cyclohexanone oxime by a method comprising the step of reacting cyclohexanone, hydrogen peroxide and ammonia in the presence of titanium silicate, a brand-new titanium silicate and a recycled titanium silicate which has been recovered from a production method of cyclohexanone oxime are used. In accordance with the present invention, cyclohexanone is subjected to ammoximation by hydrogen peroxide and ammonia with suppressing the degradation- of titanium silicate as a catalyst, to produce cyclohexanone oxime with a high yield.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: June 27, 2006
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Miyuki Oikawa, Masami Fukao
  • Patent number: 6881863
    Abstract: The present invention relates to a process for preparing 2-halogenocycloalkanone oxime which comprises subjecting a 2-halogenocycloalkenone oxime compound to reduction with hydrogen in the presence of a platinum-carried catalyst.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: April 19, 2005
    Assignee: Ube Industries, Ltd.
    Inventors: Katsumasa Harada, Yasuhisa Fukuda, Yoshinori Yamanaka
  • Patent number: 6849570
    Abstract: The present invention relates to a process for the production of a titanium silicalite shaped body by: (a) forming a formable composition containing titanium silicalite, a binder and a pasting agent, so that the Curd curve of the formable composition has a plateau value in the range from 20 to 90 mm; (b) shaping the composition of step (a) to form a green body; (c) optionally drying and (d) calcining the green body, to a titanium silicalite shaped body obtainable by that process, and to the use of such titanium silicalite shaped bodies in the epoxidation of olefins or the ammoximation of ketones.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: February 1, 2005
    Assignee: Degussa AG
    Inventors: Steffen Hasenzahl, Ralf Jantke
  • Patent number: 6844469
    Abstract: The invention relates to a process for the production of cyclohexanone oxime in which a phosphate-containing aqueous reaction medium is cycled from a hydroxylammonium synthesis zone to a cyclohexanone oxime synthesis zone and back to the hydroxylammonium synthesis zone, in which hydroxylammonium synthesis zone hydroxylammonium is formed by catalytic reduction of nitrate with hydrogen, and in which cyclohexanone oxime synthesis zone hydroxylammonium is reacted with cyclohexanone to form cyclohexanone oxime, where the concentration hydroxylammonium in the aqueous reaction medium entering the cyclohexanone oxime synthesis zone is higher than 1.0 mol/l.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: January 18, 2005
    Assignee: DSM Ip Assets B.V.
    Inventors: Arno Benneker, Paulus Johannes Jacobus Pieters, Alex Pit, Henk Oevering
  • Publication number: 20040204609
    Abstract: In producing cyclohexanone oxime by a method comprising the step of reacting cyclohexanone, hydrogen peroxide and ammonia in the presence of titanium silicate, a brand-new titanium silicate and a recycled titanium silicate which has been recovered from a production method of cyclohexanone oxime are used. In accordance with the present invention, cyclohexanone is subjected to ammoximation by hydrogen peroxide and ammonia with suppressing the degradation- of titanium silicate as a catalyst, to produce cyclohexanone oxime with a high yield.
    Type: Application
    Filed: April 6, 2004
    Publication date: October 14, 2004
    Inventors: Miyuki Oikawa, Masami Fukao
  • Publication number: 20040176592
    Abstract: A method for producing cyclohexanone oxime, which comprises the steps of (1) subjecting to an amination reaction a starting material selected from the group consisting of cyclohexanol, cyclohexanone and a mixture thereof, thereby obtaining cyclohexylamine, and (2) subjecting the obtained cyclohexylamine to a partial oxidation reaction, thereby obtaining cyclohexanone oxime, wherein a by-product (&agr;) formed in the step (1) and/or a by-product (&bgr;) formed in the step (2) are/is recycled to a reaction system of the amination reaction in the step (1).
    Type: Application
    Filed: January 6, 2004
    Publication date: September 9, 2004
    Inventors: Ken Suzuki, Hajime Nagahara