Abstract: A naphthol derivative represented by the general formula (I), [wherein Y and Y′ indicate —(CONH)n—X or —COR; X is a phenyl group, a naphthyl group, an anthraquinonyl group, a benzimidazolonyl group or a carbazolyl group; R is a hydroxyl group, an alkoxy group having 1 to 6 carbon atoms, a halogen atom, a benzyloxy group, a phenyloxy group or a phenacyloxy group; R2 is a hydrogen atom, an alkaline metal, an alkyl group having 1 to 6 carbon atoms, an acyl group having 1 to 6 carbon atoms or a phenylalkyl group; Z is a group selected from the group consisting of a hydrogen atom, a halogen atom, a nitro group, a nitroso group and an amino group (Z may be substituted on any ring of the naphthalene ring); and n is an integer of 1 or 2; provided that R2 and Z do not simultaneously indicate a hydrogen atom when both R simultaneously indicate a hydroxyl group], and a process for producing the same.

Abstract: Compounds of the formula (I) wherein R1 and R2 are H, methyl, or ethyl, have unexpected activity against ants. Compounds wherein at least one of R1 and R2 is methyl or ethyl are novel.

Abstract: The present invention relates to (cyclo)aliphatic polyisocyanates which have a content of blocked and unblocked isocyanate groups (calculated a NCO) of 5 to 25 wt. %, in which at least 95% of the isocyanate groups are present in a form blocked with blocking agents, and which also contain 0.1 to 5.0 wt. % of amines having a structural unit corresponding to formula (I) The present invention also relates to the use of the blocked polyisocyanates according to the invention as crosslinking agents for organic polyhydroxyl compounds in 1C-PUR stoving lacquers, especially for automotive clearcoats and coil coating lacquers.

Abstract: Compounds of the formula (I) wherein R1 and R2 are H, methyl, or ethyl, have unexpected activity against cockroaches. Compounds wherein at least one of R1 and R2 is methyl or ethyl are novel.

Abstract: The present invention provides a pharmaceutical or veterinary composition comprising, a carrier and an active ingredient being a compound of the following formula I: ##STR1## wherein R.sup.1 and R.sup.2 are each independently hydrogen, halogen or methoxy, as well as salts of the compound of formula I.Further provided by the invention is a method of treatment of fungal infection, comprising administering to a patient in need, an effective amount of the compound of said formula I.

Abstract: The present invention relates to a novel aryl benzoyl urea derivative represented by formula (I), in which X.sup.1 and X.sup.2 independently of one another represent hydrogen, fluoro, chloro or bromo, R.sup.1 represents chloro, bromo or trifluoromethyl, one of R.sup.2 and R.sup.4 is hydrogen and the other represents fluoro, chloro, bromo, cyano or trifluoromethyl, and R.sup.3 represents fluoro, chloro, bromo or cyano, which has a potent growth-retarding activity against pests.

Abstract: Compounds of formula (I): ##STR1## wherein R.sup.1 is H or F and R.sup.2 is CF.sub.3 or CF.sub.2 CF.sub.3, exhibit unexpectedly superior activity against cockroaches and are also useful to control other insects.

Abstract: The present invention is directed to new compositions of matter comprising the reaction products of a carboxylic acid and a urea having the formula ##STR1## where R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are selected from the group consisting of hydrogen, substituted and unsubstituted alkyl, allyl, vinyl and alkoxyl groups having from 1-6 carbon atoms, substituted and unsubstituted phenyl groups and the halides. Preferably, the reaction product of the present invention is N,N'-diformylurea or N,N'-diacetylurea. These reaction products, e.g., diformylurea, have been found to produce significantly improved growth in a variety of agricultural products when applied to the seed, to the surrounding soil or to the foliage of the emerging plant. Because of the similarity in the carbon, nitrogen, oxygen structure of these reaction products with many biological compounds, it is believed that the reaction products of the present invention may find use in a variety of biological applications.

Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, have unexpected activity against fleas. Compounds wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl are novel.

Abstract: The present invention relates to a novel benzoyl urea derivative which exhibits potent growth-retarding activity against pests and which is represented by formula (I), ##STR1## in which A represents N or CH, and X.sup.1 and X.sup.2 independently of one another represent hydrogen, fluoro, chloro or bromo.

Abstract: The invention relates to non-crystallising, amine-blocked polyisocyanates, to the preparation thereof and to their in one-component polyurethane stoving compositions, in particular for coil-coating applications.

Abstract: This invention relates to a novel trimerization catalyst system, and to a process for trimerizing organic polyisocyanates in the presence of thermally active catalyst systems. These catalyst systems comprise (A) compounds selected from the group consisting of (i) lithium salts of aliphatic or aromatic carboxylic acids, (ii) lithium salts of hydroxyl group containing compounds wherein the hydroxyl groups are directed attached to an aromatic ring, and (iii) lithium hydroxide; (B) an allophanate catalyst; and (C) an organic compound which contains at least one hydroxyl group.

Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, and wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl, are disclosed to control cockroaches.

Abstract: Compounds of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are H, methyl, or ethyl, have unexpected activity against cockroaches, ants, fleas, and termites. Compounds wherein at least one of R.sup.1 and R.sup.2 is methyl or ethyl are novel.

Abstract: The present invention provides an improved method for the preparation of an insecticidal benzoylurea having the structural formula I ##STR1##

Abstract: Compounds of formula (I): ##STR1## wherein R.sup.1 is --CF=CFCF.sub.3 or --CF.sub.2 CF=CFCF.sub.3 are useful in control of cockroaches, ants, fleas, or termites.

Abstract: The present invention is directed to a polyisocyanate containinga) polyisocyanates containing isocyanurate groups and corresponding to formula 1 ##STR1## wherein R represents the residue obtained by removing one of the isocyanate groups from 4-isocyanatomethyl-1,8-octamethylene diisocyanate,optionally in admixture withb) unreacted 4-isocyanatomethyl-1,8-octamethylene diisocyanate,c) higher homologs of the polyisocyanates set forth in formula 1 containing more than one isocyanurate group andd) a polyisocyanate containing allophanate groups.The present invention also relates to the use of these polyisocyanate mixtures, optionally in blocked form, as an isocyanate component in one- or two-component coating compositions.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is fluorine, chlorine, bromine or iodine; and A is 2,6-difluorophenyl, 2-chlorophenyl, 2-chloro-6-fluorophenyl, 2,6-dichlorophenyl or 2-fluorophenyl,with the proviso that when R.sub.1 is chlorine, A is other than 2,6-dichlorophenyl, useful as pesticides.

Abstract: Methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and Down's syndrome, treating or preventing the adverse consequences of the hyperactivity of the excitatory amino acids, as well as treating anxiety, chronic pain, convulsions and inducing anesthesia are disclosed by administering to an animal in need of such treatment a compound which has high binding to the glycine receptor.

Abstract: The invention concerns chemical compounds of formula IR.sup.1 --CON(R.sup.2)--CON(R.sup.3)--X.sup.1 --Q--X.sup.2 --GIand pharmaceutically acceptable metabolically labile esters or amides thereof, and pharmaceutically acceptable salts thereof, in which R.sup.1, R.sup.2, R.sup.3, X.sup.1, Q, X.sup.2 and G have the meanings given in the specification. The invention concerns processes for the preparation of the chemical compounds of formula I, pharmaceutical compositions containing them and their use as inhibitors of the binding of fibrinogen to glycoprotein IIb/IIIa.

Abstract: The present invention is a novel compound which is a 3,5-di-t-butyl-4-hydroxyphenylmethylhydroxylamine or derivative thereof and a pharmaceutically acceptable acid addition or base salt thereof, pharmaceutical composition and methods of use therefor. The invention compounds are now found to have activity as inhibitors of one or both of cyclooxygenase and 5-lipoxygenase providing treatment of conditions advantageously affected by such inhibition including inflammation, arthritis, pain, fever, and the like.

Abstract: New urea derivatives corresponding to the general formula 1 ##STR1## in which: R.sup.1 represents a C.sub.1 -C.sub.4 alkyl group;R.sup.2 represents:a C.sub.5 -C.sub.7 cycloalkyl groupa cycloalkylmethyl group in which the cycloalkyl radical contains from 5 to 7 carbon atomsa benzyl groupa benzyl group in which the aromatic ring bears a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a halogen atom or a nitro group;A represents an oxygen atom or a methylene radical;n represents 1 or 2;X represents an oxygen or sulfur atom;B represents a direct bond, a methylene radical or a carbonyl radical;as well as the therapeutically acceptable salts of these molecules.The invention also relates to the application of the compounds of general formula 1 in therapy, and to the preparation processes.

Abstract: The invention relates to novel substituted N-benzoyl-N'-3,5-dichlorohexafluoropropyloxyphenylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or fluorine and R.sub.2 is fluorine or chlorine, and to salts thereof; to processes and intermediates for the preparation of these compounds and to compositions containing the novel compounds for controlling insects, representatives of the order Acarina and slugs and snails, in particular plant-destructive insects.

Abstract: A class of glycyl urea derivatives is described having use in treatment of CNS dysfunctions such as epilepsy and convulsive disorders. Compounds of interest are those of the formula ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 is a group independently selected from hydrido, alkyl, aralkyl, aryloxyalkyl and arylthioalkyl, any one of which groups having a substitutable position may be substituted with one or more radicals selected from halo, alkyl of one to about ten carbon atoms, alkenyl of two to about ten carbon atoms, alkynyl of two to about ten carbon atoms, haloalkyl, alkoxy, alkylthio, alkylsulfinyl and alkylsulfonyl; or a pharmaceutically-acceptable salt thereof; with the proviso that when each of R.sup.1 and R.sup.2 is ethyl, then R.sup.3 and R.sup.4 cannot be hydrido simultaneously.

Abstract: A highly active water-dispersible pesticide formulation is prepared by dissolving at least a part of a benzoyl phenyl urea series insecticidal compound in an organic solvent, contacting the so obtained mixture with a carrier material, and pulverizing the resulting mixture. The pesticidal formulation obtained has higher pesticidal activity than formulations prepared by a conventional dry methods.

Abstract: The invention relates to novel N-[3-halo-4-(hexafluoropropoxy)-5-trifluoromethyl]phenyl-N'-benzoylureas of the formula ##STR1## wherein R.sub.1 is hydrogen or halogen and R.sub.2 and R.sub.3 are halogen, to a process and intermediate for the preparation of these compounds, and to compositions containing them for use in pest control, in particular for controlling insects and representatives of the order Acarina that attack plants and animals. The novel compounds exhibit in particular larvicidal activity.

Abstract: N-benzoyl-N'-phenoxyphenylureas of the formula (I) ##STR1## where R.sup.1 is fluorine, chlorine or methyl, R.sup.2 is fluorine, chlorine or hydrogen, R.sup.3 and R.sup.4 are each chlorine or bromine and R.sup.5 and R.sup.6 can be identical or different and are each fluorine, chlorine, bromine, trifluoromethyl or hydrogen, processes for their preparation and their use for controlling pests.

Abstract: The present invention relates to a novel benzoylurea derivative represented by the formula, ##STR1## its production and insecticides containing it as an active ingredient.

Abstract: Compounds of the formula ##STR1## wherein A is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group;B is a hydrogen atom, a halogen atom, a methyl group, or a methoxy group, with the proviso that A and B ar not both a hydrogen atom;X and Y each are an oxygen atom or a sulfur atom;R is a hydrogen atom, an alkyl group, a hydroxy group, an alkoxy group, an alkoxymethyl group, an acyl group, or an alkoxycarbonyl group;R.sub.1 is a hydrogen atom, an alkyl group, a halogen substituted alkyl group, an alkoxy substituted alkyl group, an alkylthio substituted alkyl group, a cyano substituted alkyl group, a 1-cycloalkenyl group, a benzyl group, a halogen substituted benzyl group, a hydroxy group, an alkoxy group, an acyl group, an alkoxycarbonyl group, an alkoxythiocarbonyl group, an alkylsulfonyl group, or a phenylsulfonyl group, while furthermore R and R.sub.1 together with the group ##STR2## indicated in the above formula may form a ring system; and R.sub.

Abstract: The invention relates to novel substituted N-benzoyl-N'-2,5-dihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein each of R.sub.1 and R.sub.2 is halogen, with the proviso that R.sub.1 and R.sub.2 may not simultaneously be chlorine, R.sub.3 is a mono- or polyhalogenated C.sub.1 -C.sub.7 alkyl group, R.sub.4 is hydrogen, halogen, methyl, methoxy or methylthio and R.sub.5 is halogen, methyl, methoxy or methylthio, to processes and intermediates for the preparation thereof, to the use thereof in pest control and to compositions containing, as active ingredient, at least one compound of formula I. The preferred area of application of said novel compounds is the control of pests of animals and plants.

Abstract: A novel benzxoylurea derivative represented by the formula (I) described below, its production and an insecticidal and/or acaricidal composition containing it as an active ingredient: ##STR1## wherein R.sub.1 is a chlorine or fluorine atom, each of R.sub.2 and R.sub.3, wherein may be the same or different, is a fluorine or hydrogen atom, R.sub.4 is a chlorine or hydrogen atom, R.sub.5 is a halogen atom or a methyl or trifluoromethyl group, and X is an oxygen or sulfur atom.

Abstract: The invention relates to novel substituted N-benzoyl-N'-2,5-dichloro-4-hexafluoropropyloxyphenylureas of the formula ##STR1## wherein R.sub.1 is hydrogen, fluorine, chlorine or methoxy, and R.sub.2 is fluorine, chlorine or methoxy, and to the salts thereof; to processes and intermediates for the preparation of these compounds and to compositions containing the novel compounds for controlling insects and representatives of the order Acarina, in particular plant-destructive insects.

Abstract: Insecticidal substituted benzoyl(thio) ureas of the formula ##STR1## in which Q stands for oxygen or sulphur,R.sup.1 stands for hydrogen, halogen, nitro, methyl or trifluoromethyl,R.sup.2 stands for hydrogen, fluorine or chlorine,R.sup.3 stands for hydrogen, fluorine or chlorine,R.sup.4 stands for hydrogen or fluorine,R.sup.5 stands for hydrogen or halogen andn stands for the numbers 2, 3 or 4.Intermediates of the formula ##STR2## are also new.

Abstract: A class of particularly active insecticidal compounds: N-(halobenzoyl)-N'-2-halo-4-[1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy]-p henyl-ureas, the preparation of such compounds and their use against infestations by insects.

Abstract: The invention relates to novel substituted N-benzoyl-N'-2,3,5-trihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein R.sub.1 is CF.sub.3, CF.sub.2 CF.sub.3 or CF.sub.2 F.sub.2 CF.sub.3, to the preparation of these compounds and to intermediates for their synthesis. The invention further relates to the use of the novel compounds for use in pest control and to pesticidal compositions which contain at least one compound of formula I as active component. The preferred utility is the control of pests of animals and plants.

Abstract: The invention relates to novel oxime ethers of the formula I ##STR1## wherein R.sub.1 is hydrogen, halogen, lower alkyl, lower haloalkyl, lower alkoxy, lower haloalkoxy, lower alkylthio, lower haloalkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower haloalkylsulfinyl, lower haloalkylsulfonyl or nitro, each of R.sub.2 and R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or lower haloalkoxy, and Q is an unsubstituted or substituted lower alkyl, lower alkenyl, lower alkynyl or cycloalkyl group, a lower alkanoyl radical, an aliphatic, cycloaliphatic, aromatic or heterocyclic acyl radical which may be substituted or unsubstituted, a carbonyl or thiocarbonyl radical, an aryl or aralkyl radical, an acylimidomethyl radical, a phthalimidomethyl radical or a heterocyclic radical.These compounds are able to act as antidotes or safeners for protecting cultivated plants from the phytotoxic action of aggressive herbicides.

Abstract: Certain N-2,6-dialkyl- or N-2,6-dialkoxyphenyl-N'-arylalkylurea compounds are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT), and are thus useful agents for the treatment of hypercholesterolemia or atherosclerosis.

Abstract: Novel aniline compounds that are useful in preparing N-aroyl N'-phenyl ureas having alkyl substituents in the 2-, 3-, 5- and 6-positions and haloalkoxy in the 4-position of the N'-phenyl which are more active and have a broader spectrum of effectiveness than the known benzoylurea insecticides.

Abstract: Compounds are disclosed having formula: ##STR1## wherein: R is Cl, F;R.sub.1 is H, Cl, F;R.sub.2 and R.sub.5, equal to or differing from each other, are H, halogen, alkyl C.sub.1 -C.sub.4 ;R.sub.3 and R.sub.4, equal to or differing from each other, are: H, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, alkenyl, haloalkenyl, alkenyloxy, haloalkenyloxy or alkynyl;Z is O, S or a group NR.sub.7, wherein R.sub.7 is alkyl C.sub.1 -C.sub.3 or H;Y is alkylene C.sub.2 -C.sub.4, haloethylene or haloethenyl;R.sub.6 is alkyl C.sub.1 -C.sub.4, haloalkyl C.sub.1 -C.sub.4, alkenyl C.sub.3 -C.sub.4, haloalkenyl C.sub.3 -C.sub.4, cycloalkyl C.sub.3 -C.sub.4, halocycloalkyl C.sub.3 -C.sub.4 or cycloalkenyl C.sub.3 -C.sub.4.The compounds having formula (I) are endowed with an elevated insecticide activity, which shows itself chiefly against insect larvae and eggs.

Abstract: Compounds of the general formula I ##STR1## in which A denotes a radical of the formula A.sup.1, A.sup.2 or A.sup.3 ##STR2## R.sup.1 to R.sup.3 in each case independently of one another denote hydrogen or halogen,the radicals R.sup.4 in each case independently of one another denote halogen, (C.sub.1 -C.sub.3)halogenoalkyl or nitro,R.sup.5 denotes (C.sub.1 -C.sub.5)alkyl, which can be halogenated,X denotes oxygen or sulfur,n denotes a number from 0 to 2 andm denotes a number from 1 to 4 with the proviso that (R.sup.4).sub.m does not by itself denote halogen or by itself denote nitro, and where A=A.sup.1, salts thereof which can be used in agriculture, have advantageous acaricidal and insecticidal properties.Processes for the preparation of the compounds of the formula I are furthermore described.

Abstract: Novel substituted N-benzoyl-N'-2,5-dihalo-4-perfluoroalkoxyphenylureas of formula I ##STR1## in which R.sub.1 is hydrogen, fluorine, chlorine or bromine; R.sub.2 is fluorine or chlorine; each of R.sub.3 and R.sub.4 is fluorine, chlorine or bromine; and n is 2, 3, 4, 5, 6, 7 or 8, processes and intermediates for their prepraration, their use in pest control, and pesticidal compositions that contain at least one compound of formula I as active ingredient, are disclosed. The preferred field of application is the control of pests in and on animals and plants.

Abstract: The invention relates to novel substituted N-benzoyl-N'-2,3,5-trihalo-4-haloalkoxyphenylureas of formula I ##STR1## wherein R.sub.1 is CF.sub.3, CF.sub.2 CF.sub.3 or CF.sub.2 CF.sub.2 CF.sub.3, to the preparation of these compounds and to intermediates for their synthesis. The invention further relates to the use of the novel compounds for use in pest control and to pesticidal compositions which contain at least one compound of formula I as active component. The preferred utility is the control of pests of animals and plants.

Abstract: Disclosed herein are N-acyl-N-naphthoylglycines and methods of their preparation. The N-acyl-N-naphthoylglycines are novel aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

Abstract: Benzoyl ureas of the formula ##STR1## are prepared by starting from benzoyl derivatives of the formulaQ-COHalwhich are converted via the corresponding azides into the isocyanates, which are in turn reacted with corresponding benzamides.

Abstract: The present invention relates to a novel benzoylurea derivative represented by the formula, ##STR1## its production and insecticides containing it as an active ingredient.

Abstract: Novel 1-(4-phenoxyphenyl)-3-benzoyl urea compounds are provided together with methods for their preparation and the use of said compounds as the active toxicant in pesticidal compositions.

Abstract: N-Benzoyl-N'-(2,3-dichloro-4-phenoxy)-phenylureas of the general formula I ##STR1## where R.sup.1 is halogen, R.sup.2 is hydrogen or halogen, R.sup.3 is halogen or C.sub.1 -C.sub.4 -haloalkoxy, and R.sup.4 is hydrogen or halogen, pesticides containing compounds I as active ingredients, and methods of combating pests.

Abstract: Novel 1-(alkylphenoxyphenyl)-3-benzoyl ureas and a process for their preparation are provided. The novel ureas are useful as the active toxicant in pesticidal composition.

Abstract: N-aroyl N'-phenyl ureas having the formula ##STR1## wherein: Ar is a substituted phenyl, pyridyl or pyrimidinyl radical wherein the substituents are chloro, bromo, fluoro C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy, with the proviso that at least one substituent is positioned ortho to the carbonyl group; R.sub.3 and R.sub.4 are individually H or C.sub.1 -C.sub.4 alkyl or together they form the group ##STR2## Y is O or S; X.sub.1, X.sub.2, X.sub.3 and X.sub.4 are individually H, halogen, C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, alkylcarbonyl, alkoxycarbonyl, C.sub.1 -C.sub.3 alkylthio, NO.sub.2, CN or NR.sub.5 R.sub.6 wherein R.sub.5 and R.sub.6 are H or C.sub.1 -C.sub.3 alkyl with the provisos that at least one of X.sub.1, X.sub.2, X.sub.3 or X.sub.4 is other than H and (a) when three of X.sub.1, X.sub.2, X.sub.3 or X.sub.4 are H, the fourth substitution cannot be halogen or alkyl, (b) when X.sub.1 and X.sub.3 are H, X.sub.2 and X.sub.4 cannot both be halogen, (c) when X.sub.2 and X.sub.

Abstract: Certain N-2,6-dialkyl- or N-2,6-dialkoxyphenyl-N'-arylalkylurea compounds are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT), and are thus useful agents for the treatment of hypercholesterolemia or atherosclerosis.