Polycyclo Ring System Patents (Class 564/458)
  • Patent number: 9034085
    Abstract: A composition of matter, and method to make same, for a nano-based material including a nanocarbon support to which is attached an aliphatic amine. In particular, the composition of matter is an aliphatic amine-nanocarbon material that includes a nanocarbon (NC) support, such as C60, nano-graphite, graphene, nanocarbon ribbons, graphite intercalation compounds, graphite oxide, nano-coal, nanohorns, and combinations thereof, and further includes an aliphatic amine, such as polyethyleneimine (PEI).
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: May 19, 2015
    Assignee: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Andrew R. Barron, Eoghan Dillon
  • Publication number: 20140275323
    Abstract: Oligomer-grafted nanofiller compositions and composites including oligomer-grafted nanofillers are disclosed. An oligomer-grafted nanofiller composition for disposition in a polymer matrix, the polymeric matrix comprising polymers derived from a plurality of polymerizable units, can include a nanoparticle, one or more coupling groups bonded to the nanoparticle; and one or more oligomers bonded to the one or more coupling groups. In an embodiment the oligomer is derived from two or more polymerizable units, at least one polymerizable unit being at least substantially similar to at least one of the polymerizable units of the polymer matrix. In another embodiment the oligomer comprises two or more polymerizable units and improves dispersion, interfacial strength, or both dispersion and interfacial strength between the nanoparticle and the polymer matrix. Composites and methods are also disclosed.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: Francis R. Thibodeau, Yuqiang Qian, Andreas Stein, Christopher W. Macosko
  • Patent number: 8784520
    Abstract: Methods of treating a plurality of particles involve functionalizing a plurality of microscale diamond particles by covalently bonding one or more molecular groups selected from OH functional groups, —COOH functional groups, —R—COOH functional groups, wherein R includes alkyls, -Ph-COOH functional groups, wherein Ph includes phenolics, polymers, oligomers, monomers, glycols, sugars, ionic functional groups, metallic functional groups, and organo-metallic functional groups to outer surfaces of at least some particles of the plurality of microscale diamond particles. A stability of the functionalized plurality of microscale diamond particles in dispersion is increased as compared to a plurality of microscale diamond particles that has not been functionalized.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: July 22, 2014
    Assignee: Baker Hughes Incorporated
    Inventors: Soma Chakraborty, Gaurav Agrawal
  • Patent number: 8636830
    Abstract: A composition of matter, and method to make same, for a nano-based material including a nanocarbon support to which is attached an aliphatic amine. In particular, the composition of matter is an aliphatic amine-nanocarbon material that includes a nanocarbon (NC) support, such as C60, nano-graphite, graphene, nanocarbon ribbons, graphite intercalation compounds, graphite oxide, nano-coal, nanohorns, and combinations thereof, and further includes an aliphatic amine, such as polyethyleneimine (PEI).
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: January 28, 2014
    Assignee: William Marsh Rice University
    Inventors: Andrew R. Barron, Eoghan Dillon
  • Publication number: 20130000209
    Abstract: Methods of treating a plurality of particles comprise functionalizing a plurality of microscale diamond particles by covalently bonding one or more molecular groups selected from the group consisting of —OH functional groups, —COOH functional groups, —R—COOH functional groups, wherein R comprises alkyls, —Ph—COOH functional groups, wherein Ph comprises phenolics, polymers, oligomers, monomers, glycols, sugars, ionic functional groups, metallic functional groups, and organo-metallic functional groups to outer surfaces of at least some particles of the plurality of microscale diamond particles. A stability of the functionalized plurality of microscale diamond particles in dispersion is increased as compared to a plurality of microscale diamond particles that has not been functionalized.
    Type: Application
    Filed: June 30, 2011
    Publication date: January 3, 2013
    Applicant: BAKER HUGHES INCORPORATED
    Inventors: Soma Chakraborty, Gaurav Agrawal
  • Publication number: 20120251449
    Abstract: The present invention claims fluoro- & iodo-containing aldehydes as ALDH substrates for use as diagnostic imaging agents or as therapeutic agents. The aldehydes are both directly and indirectly attached to an aromatic or a straight chain ring. ALDH activity was monitored either by the formation of acid-product or consumption of aldehyde substrates.
    Type: Application
    Filed: December 22, 2010
    Publication date: October 4, 2012
    Inventors: Vijaya Raj Kuniyil Kulangara, Alan Cuthbertson, Peter Iveson, Chitralekha Rangaswamy, Veena Rao, Rajiv Bhalla
  • Publication number: 20120024153
    Abstract: A composition of matter, and method to make same, for a nano-based material including a nanocarbon support to which is attached an aliphatic amine. In particular, the composition of matter is an aliphatic amine-nanocarbon material that includes a nanocarbon (NC) support, such as C60, nano-graphite, graphene, nanocarbon ribbons, graphite intercalation compounds, graphite oxide, nano-coal, nanohorns, and combinations thereof, and further includes an aliphatic amine, such as polyethyleneimine (PEI).
    Type: Application
    Filed: June 13, 2011
    Publication date: February 2, 2012
    Applicant: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Andrew R. Barron, Eoghan Dillon
  • Publication number: 20110232178
    Abstract: Compounds and methods that release 1-methylcyclopropene, 1-trifluoromethylcyclopropene, and other substituted cyclopropenes are disclosed. The compounds and methods overcome present limitations for storage, transportation, and application of the cyclopropene containing compounds by using light, including sunlight, and/or heat as the primary release trigger. Additional products released include innocuous gases and value added aryl-group compounds.
    Type: Application
    Filed: March 23, 2011
    Publication date: September 29, 2011
    Inventors: John Perrin Davis, Cheryl D. Stevenson
  • Patent number: 7981930
    Abstract: Kits comprising an M2 inhibitor selected from amantadine and rimantadine; ribavirin, and a neuraminidase inhibitor (NAi) in an amount that is antivirally effective in the combination, an oral dosage form containing 75-250 mg of the M2 inhibitor, an oral dosage form comprising 100-400 mg of ribavirin and a neuraminidase inhibitor are provided for the treatment of influenza. Some embodiments of the kits comprise an oral dosage form containing 75-250 mg of the M2 inhibitor, an oral dosage form comprising 100-400 mg of ribavirin, and a neuraminidase inhibitor.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: July 19, 2011
    Assignee: Adamas Pharmaceuticals, Inc.
    Inventors: Jack Nguyen, Gregory T. Went, Paul Spence, Timothy J. Fultz, David Chernoff, Terry L. Burkoth, Rowan Chapman, Mickey S. Urdea
  • Publication number: 20110124912
    Abstract: The invention at hand describes functionalized diols of diamondoids, in which one of the two hydroxy groups is masked by a protective group, as well as methods for producing these functionalized diols. The protective group is a group —CHR1R2, wherein R1 and R2 stand for alkyl groups and the protective group comprises at least one halogen atom. The monoethers of the diamondoid diols according to the present invention are produced by reacting the diamondoid diol with a halogenated alcohol CHOHR1R2 in the presence of a catalyst acid. The monoetherified diols allow for the targeted production of derivatives of diamondoids, for example, of the corresponding aminoalcohols and aminocarboxylic acids. For that purpose, the diamondoid monoether is reacted in a first step with a halogen nitrile in a Ritter reaction to the corresponding monoether amide.
    Type: Application
    Filed: June 2, 2009
    Publication date: May 26, 2011
    Applicant: JUSTUS-LIEBIG-UNIVERSITAT GIESSEN
    Inventors: Peter R. Schreiner, Hartmut Schwertfeger
  • Publication number: 20110082053
    Abstract: Provided is a molecular rectifier comprised of a diamondoid molecule and an electron acceptor attached to the diamondoid molecule. The electron acceptor is generally an electron accepting aromatic species which is covalently attached to the diamondoid.
    Type: Application
    Filed: January 30, 2009
    Publication date: April 7, 2011
    Inventors: Wanli Yang, Zhi-Xun Shen, Harindran C. Manoharan, Nicholas A. Melosh, Michael A. Kelly, Andrey A. Fokin, Peter R. Schreiner, Jason C. Randel
  • Patent number: 7858660
    Abstract: Compositions, kits and methods are provided for the treatment or prophylaxis of influenza.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: December 28, 2010
    Assignee: Adamas Pharmaceuticals, Inc.
    Inventors: Jack Nguyen, Gregory T. Went, Paul Spence, Timothy J. Fultz, David Chernoff, Terry L. Burkoth, Rowan Chapman, Mickey S. Urdea
  • Publication number: 20100317767
    Abstract: Disclosed is a fullerene film which can be easily formed by a wet process without deteriorating the intrinsic properties of a fullerene by using a fullerene derivative as a raw material. Also disclosed are a fullerene polymer, a method for producing a fullerene film, and a method for producing a fullerene polymer. A fullerene film or a fullerene polymer maintaining the intrinsic properties of the fullerene is obtained by coating a base with a solution of a fullerene derivative which is decomposed at a temperature lower than the thermal decomposition temperature of the fullerene, for example one represented by the formula below, and then heating the thus-obtained coating film at a temperature higher than the thermal decomposition temperature of the fullerene derivative but lower than the thermal decomposition temperature of the fullerene.
    Type: Application
    Filed: December 26, 2007
    Publication date: December 16, 2010
    Applicants: FRONTIER CARBON CORPORATION, MITSUBISHI CHEMICAL CORPORATION
    Inventors: Katsutomo Tanaka, Masatoshi Takagi
  • Patent number: 7838704
    Abstract: The present invention relates to a synthetic method for terbinafine and analogues thereof using metal catalysts, preferably Ni(II) salts and/or complexes.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: November 23, 2010
    Assignee: F.I.S. Fabbrica Italiana Sintetici S.p.A.
    Inventors: Federico Della Negra, Cristiano Grandini, Mariano Stivanello
  • Publication number: 20100190985
    Abstract: This invention is related to heteroatom containing diamondoids (i.e., “heterodiamondoids”) which are compounds having a diamondoid nucleus in which one or more of the diamondoid nucleus carbons has been substitutionally replaced with a noncarbon atom. These heteroatom substituents impart desirable properties to the diamondoid. In addition, the heterodiamondoids are functionalized affording compounds carrying one or more functional groups covalently pendant therefrom. This invention is further related to polymerizable functionalized heterodiamondoids. In a preferred aspect of this invention the diamondoid nuclei are triamantane and higher diamondoid nuclei. In another preferred aspect, the heteroatoms are selected to give rise to diamondoid materials which can serve as n- and p-type materials in electronic devices can serve as optically active materials.
    Type: Application
    Filed: December 14, 2009
    Publication date: July 29, 2010
    Applicant: Chevron U.S.A. Inc.
    Inventors: Shenggao Liu, Robert M. Carlson, Jeremy E. Dahl
  • Patent number: 7405324
    Abstract: The present invention concerns a new process for synthesising aminoadamantanes of formula I in which R1 and R2 are identical or different and are H or a straight or branched alkyl group comprising from 1 to 6 carbon atoms, and addition salts thereof with inorganic or organic acids, in particular memantine hydrochloride (1-amino-3,5-dimethyladamantane hydrochloride).
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: July 29, 2008
    Assignee: A.M.S.A. Anonima Materie Sintetiche E. Afini S.p.A.
    Inventors: Enrico Vigano′, Ernesto Landonio, Simona Lanfranconi, Renato Molteni
  • Patent number: 6930128
    Abstract: The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosage sufficient to inhibit cell mitosis. The application discloses novel compounds used in the methods.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: August 16, 2005
    Assignee: The Children's Medical Center Corporation
    Inventors: Robert John D'Amato, Moses Judah Folkman
  • Publication number: 20040110987
    Abstract: A method for preparing metal salts of organic sulfonic acids such as tin alkane sulfonates by electrolysis is described.
    Type: Application
    Filed: December 6, 2002
    Publication date: June 10, 2004
    Inventors: George P. Kinstle, Alex T. Magdics, Thomas E. Nappier
  • Patent number: 6555959
    Abstract: A material for a light emitting device which is a compound represented by the following formula (I): wherein Ar1 and Ar6, which are the same or different, each represents a divalent aryl group or a divalent heterocyclic group; R2, R3, R7 and R8, which are the same or different, each represents an aryl group, a heterocyclic group or an aliphatic hydrocarbon group; R4a, R5a, R9a and R10a, which are the same or different, each represents a hydrogen atom or a monovalent group, and at least one of R4a, R5a, R9a and R10a represents an electron withdrawing group having a Hammett's &sgr;p value of 0.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: April 29, 2003
    Assignee: Fuji Photo Film Co., Ltd.
    Inventor: Kazumi Nii
  • Patent number: 6392104
    Abstract: In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): wherein R1 and R2 independently represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a cycloalkyl group; or R1 and R2 may bond together to form a double bond or an aromatic or non-aromatic ring; Y is O or OH and n=1 to 3; or the imide compound and a co-catalyst (e.g., a transition metal compound), an adamantane derivative having a functional group such as a nitro group, an amino group, a hydroxyl group, a carboxyl group, a hydroxymethyl group and an isocyanato group is oxidized with oxygen. According to the above method, an adamantane derivative having a hydroxyl group together with a functional group such as a nitro group, an amino group, a hydroxyl group, a carboxyl group, a hydroxymethyl group and an isocyanato group is efficiently obtained.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: May 21, 2002
    Assignee: Daicel Chemical Industries, Ltd.
    Inventors: Yasutaka Ishii, Tatsuya Nakano, Naruhisa Hirai
  • Patent number: 6380434
    Abstract: Disclosed herein are fullerene derivatives of the formula, F(—E)n(—R1)p(—R2)q, in which F is a fullerene core; E is a nucleophilic substituent; R1 is an amino group or a hydroxyl group; R2 is an epoxide group and n is 1-30; p is 1-20; and q is 0-10. Also disclosed is a method of preparing such derivatives using polynitrofullerenes or polycyclosulfated fullerenes as intermediates.
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: April 30, 2002
    Inventor: Long Y. Chiang
  • Patent number: 6114392
    Abstract: The invention relates to the use of agmatine, in the treatment of acute neurotrauma (such as stroke) and degenerative disorders of the central and peripheral nervous system (such as dementia).The invention further provides novel compounds of general formula I (which are quinuclidine derivatives), formula II (which are norbornane derivatives), formula III (which are adamantane derivatives), and formula IV (which are phenothiazine derivatives): ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen, hydroxy, substituted or unsubstituted C.sub.1-4 alkyl, substituted or unsubstituted C.sub.1-4 alkoxy, halogeno, amino, phenyl, or R.sub.4 NR.sub.5 ; R.sub.4 and R.sub.5 are each independently hydrogen, or (CH.sub.2)n--[NH(CH.sub.2)x]y--NHR.sub.6, or (CH.sub.2)n--[NH(CH.sub.2)x]y--NH--NHR.sub.6, or (CH.sub.2)n--[NH(CH.sub.2)x]y--(NR.sub.7 .dbd.)CNHR.sub.6, or (CH.sub.2)n--[NH(CH.sub.2)x]y--NH(NR.sub.7 .dbd.)CNHR.sub.6 wherein n is from 0-5, y is from 0-5 and each x is independently from 1-5; R.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: September 5, 2000
    Inventors: Gad M. Gilad, Varda H. Gilad
  • Patent number: 6046361
    Abstract: Polyorganofullerene and polyhydroxyorganofullerene derivatives have the respective formulas, F--(E).sub.n and F--(E).sub.n --(OH).sub.m, in which F is a fullerene core; E is a nucleophilic substituent; --OH is a hydroxy group; n is 2-30; and m is 1-20. Also disclosed is a method of preparing such polyorgano-fullerene and polyhydroxyorganofullerene derivatives using polynitrofullerenes or polycyclosulfated fullerenes as intermediates.
    Type: Grant
    Filed: November 20, 1997
    Date of Patent: April 4, 2000
    Inventor: Long Y. Chiang
  • Patent number: 5986142
    Abstract: The present invention provides a process for preparing compounds of Formula I: ##STR1## wherein R.sub.1 is methyl by reduction of a camphene intermediate with a reducing agent.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: November 16, 1999
    Assignee: Poli Industria Chimica SpA
    Inventors: Ambrogio Magni, Giovanni Signorelli
  • Patent number: 5679861
    Abstract: The present invention is directed to C.sub.60 diamine adducts, processes for preparing them and polymers prepared from them. C.sub.60 diamine adducts is a symmetrical icosahegron which is composed of 12 pentagons and 20 hexagons and links to 2 to 4 diamines. The processes for preparing the product comprises the steps of: adding C.sub.60 in benzene or toluene of a constant concentration to a certain amount of linear aliphatic diamine having the structural formula H.sub.2 N--(CH.sub.2)n--NH.sub.2 wherein n=2, 4 or 6 for reaction, or adding a definite amount of C.sub.60 directly to linear diamine of a definite concentration to produce C.sub.60 diamine adducts. Elemental analysis shows that the product contain about 5.9% nitrogen, about 72.6% carbon and about 3.84% hydrogen, and the number of diamine linked to C.sub.60 is in the range of 2 to 4. C.sub.60 diamine is useful as a polymerization monomer for the preparation of polyamides or relevant polymers.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 21, 1997
    Assignee: Industrial Technology Research Institute
    Inventors: Tung-Ying Kuo, Jih-Ru Hwu, Tsong-Ming Chang
  • Patent number: 5599998
    Abstract: The present invention provides a method to prepare aminated bridgehead polycyclic hydrocarbons by reacting bridgehead halo polycyclic hydrocarbons with lithium metal under conditions of sonication and aminating the resultant lithio compounds.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: February 4, 1997
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: George A. Kraus
  • Patent number: 5235108
    Abstract: This invention relates to a process for preparing secondary alkylamine by selective hydrogenation of alkylnitrile using a nickel-containing catalyst which contains copper as promoter, said catalyst having a selectivity, as herein defined, of not more than 8.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: August 10, 1993
    Assignee: Engelhard De Meern B.V
    Inventors: Frederik Borninkhof, Eugene G. M. Kuijpers, Pieter H. Berben
  • Patent number: 5232836
    Abstract: Vitamin D derivatives corresponding to the following formula I ##STR1## in which R.sub.1 denotes a substituted alkyl group having 1 to 15 carbon atoms, in particular the side chains of vitamin D.sub.2 (C.sup.20 to C.sup.28) or D.sub.3 (C.sup.20 to C.sup.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: August 3, 1993
    Assignee: Ire-Medgenix S.A.
    Inventors: Roger Bouillon, Pierre J. De Clerco, Pierre Eliard, Maurits Vanderwalle
  • Patent number: 5232526
    Abstract: This invention is for new compounds, namely, diethanolammoniummethylcubane nitrates, a composition of diethanolammonium methylcubyl nitrates - hydroxylammonium nitrate (HAN) solutions and their method of use as aqueous liquid gun propellant ingredients.
    Type: Grant
    Filed: July 10, 1992
    Date of Patent: August 3, 1993
    Assignee: Thiokol Corporation
    Inventors: Rodney L. Willer, Alfred G. Stern
  • Patent number: 5041673
    Abstract: This invention relates to novel derivatives of tetralin, to the processes for their preparation, to their use as aminopeptidase inhibitors and to their end-use application as immunomodulators and as analgesic agents.
    Type: Grant
    Filed: January 4, 1990
    Date of Patent: August 20, 1991
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Hugues d'Orchymont, Celine Tarnus
  • Patent number: 4878968
    Abstract: A compound having the following formula: ##STR1## wherein R.sup.1 is --N.sup.+ H.sub.3 as found in claim 1 and R.sup.2 is either the same as F.sup.1 or hydrogen. "A" is an oxidizing anion, and X is selected to provide a neutral charge balance for the compound. A method of making a compound of the indicated structure from a compound of similar structure by an anion exchange process is also disclosed. Finally, propellant formulations incorporating the novel compounds of the present invention as fuels and oxidizers are disclosed.
    Type: Grant
    Filed: January 12, 1988
    Date of Patent: November 7, 1989
    Assignee: Morton Thiokol, Inc.
    Inventors: Rodney L. Willer, Glen T. Cunkle, Nathan Klein
  • Patent number: 4622430
    Abstract: Pentacyclo[6.3.0.0..sup.2,6.0.sup.3,10.0.sup.5,9 ]undecane and its derivatives are prepared. The compounds find use as antiviral agents.
    Type: Grant
    Filed: December 21, 1982
    Date of Patent: November 11, 1986
    Assignee: Noristan Limited
    Inventors: Theodor G. Dekker, Douglas W. Oliver, Friedrich O. Snyckers, Cornelis J. van der Schyf
  • Patent number: 4332969
    Abstract: Novel substituted 11-aminoundecanols of the formula ##STR1## and a process for their preparation are described; in the formula, R.sub.1 and R.sub.3 independently of one another are hydrogen or alkyl having 1-8 C atoms and R.sub.2 and R.sub.4 independently of one another are alkyl having 1-8 C atoms, or R.sub.1 and R.sub.2 and/or R.sub.3 and R.sub.4 together with the bonding C atom form a cycloaliphatic ring having 4-8 C atoms, and R.sub.5 and R.sub.6 independently of one another are hydrogen or alkyl having 1-4 C atoms. The compounds of the formula I are valuable active compounds for combating plant pests.
    Type: Grant
    Filed: February 26, 1980
    Date of Patent: June 1, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Dieter Reinehr, Adolf Hubele
  • Patent number: 4314942
    Abstract: An improved synthetic process for the removal of an allyl group in an allylic ester or an allyloxycarbonyl group in an allylic carbonate or carbamate by reaction with 2-ethylhexanoic acid or an alkali metal salt thereof and a catalytic amount of an organic-soluble palladium complex is disclosed herein.
    Type: Grant
    Filed: January 10, 1979
    Date of Patent: February 9, 1982
    Assignee: Schering Corporation
    Inventor: Stuart W. McCombie
  • Patent number: 4275237
    Abstract: Heavy reaction product after separation as by distillation of light reaction product or diadduct from a reaction mixture obtained by reaction of olefinically unsaturated nitriles with monoolefinic hydrocarbons containing an allylic hydrogen atom is hydrogenated to produce a polyamine mixture useful as an epoxy resin hardener yielding cured resins exhibiting low water absorption.
    Type: Grant
    Filed: August 6, 1979
    Date of Patent: June 23, 1981
    Assignee: Philips Petroleum Company
    Inventors: Charles A. Drake, Ralph P. Williams
  • Patent number: RE39744
    Abstract: In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): wherein R1 and R2 independently represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a cycloalkyl group; or R1 and R2 may bond together to form a double bond or an aromatic or non-aromatic ring; Y is O or OH and n=1 to 3; or the imide compound and a co-catalyst (e.g., a transition metal compound), an adamantane derivative having a functional group such as a nitro group, an amino group, a hydroxyl group, a carboxyl group, a hydroxymethyl group and an isocyanato group is oxidized with oxygen. According to the above method, an adamantane derivative having a hydroxyl group together with a functional group such as a nitro group, an amino group, a hydroxyl group, a carboxyl group, a hydroxymethyl group and an isocyanato group is efficiently obtained.
    Type: Grant
    Filed: March 5, 1998
    Date of Patent: July 24, 2007
    Assignee: Daicel Chemical Industries, Ltd.
    Inventors: Yasutaka Ishii, Tatsuya Nakano, Naruhisa Hirai