Three Or More Amino Nitrogens Containing Patents (Class 564/512)
  • Patent number: 9458100
    Abstract: The synthesis, growth inhibition and radioprotective activity of the PrC-210 aminothiol, 3-(methyl-amino)-2-((methylamino)methyl)propane-1-thiol, and its polyamine and thiolated polyamine progenitors are reported. All of the molecules significantly inhibited growth of cultured normal human fibroblasts. The combination of an ROS-scavenging thiol group and a positively charged alkyl-amine backbone provided the most radioprotective aminothiol molecule.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: October 4, 2016
    Assignee: Wisconsin Alumni Research Foundation
    Inventor: William E. Fahl
  • Patent number: 9233338
    Abstract: This invention provides novel compositions comprising substituted polyamines as acid gas scrubbing solutions and methods of using the compositions in an industrial system. The invention relates to the use of such polyamine compounds in industrial processes to remove acidic contaminants from natural and industrial fluid streams, such as natural gas, combustion gas, natural gas, synthesis gas, biogas, and other industrial fluid streams. The compositions and methods of the invention are useful for removal, absorption, or sequestration of acidic contaminants and sulfide contaminants including CO2, H2S, RSH, CS2, COS, and SO2.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: January 12, 2016
    Assignee: NALCO COMPANY
    Inventors: Alan M. Blair, Keith N. Garside, William J. Andrews, Kailas B. Sawant
  • Publication number: 20150148543
    Abstract: The invention features methods and compositions for the synthesis of multimerizing agents.
    Type: Application
    Filed: January 28, 2015
    Publication date: May 28, 2015
    Inventors: Feng Li, Yihan Wang
  • Patent number: 9024028
    Abstract: The invention features methods and compositions for the synthesis of multimerizing agents. An exemplary method for producing AP20187 may comprise: (a) coupling 2-N,Ndimethylaminomethyl-1,3-diaminopropane with AP20792 to produce the dimeric alcohol, AP20793; and (b) coupling the AP20793 so produced with API7362 to yield AP20187. In particular embodiments, the method further includes the step of producing API7362 by coupling API7360 with methyl-L-pipecolic acid, or a salt thereof.
    Type: Grant
    Filed: January 26, 2012
    Date of Patent: May 5, 2015
    Assignee: ARIAD Pharmaceuticals, Inc.
    Inventors: Feng Li, Yihan Wang
  • Patent number: 9000217
    Abstract: A process for preparing high molecular weight acyclic polyamines comprising providing a reaction mixture that includes at least a first component comprising a first organic, nitrogen-containing compound that contains at least two non-tertiary amine groups separated from one another by a ternary or higher carbon atom spacing that can be transaminated in the presence of a hydrogenation/dehydrogenation catalyst to form a mixture of higher molecular weight, acyclic polyamines while minimizing the formation of cyclic polyamines.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: April 7, 2015
    Assignee: DOW Global Technologies LLC
    Inventor: Stephen W. King
  • Patent number: 8993759
    Abstract: A transamination process is described to prepare polyamine product mixtures from reactants comprising mixed nitrogen-containing compounds with binary carbon spacing between nitrogen-containing groups (a binary component). A second nitrogen-containing component with a second carbon atom spacing between nitrogen-containing groups may also be employed. The molar ratio between the binary and second components can be adjusted to customize the product composition for desired end uses.
    Type: Grant
    Filed: October 20, 2011
    Date of Patent: March 31, 2015
    Assignee: DOW Global Technologies LLC
    Inventor: Stephen W. King
  • Patent number: 8987518
    Abstract: The present invention relates to polyamines and to a process for preparing polyamines.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: March 24, 2015
    Assignee: BASF SE
    Inventors: Ansgar Gereon Altenhoff, Christoph Mueller, Christian Mueller, Andreas Kunst, Thomas Reissner, Kirsten Dahmen
  • Publication number: 20150068533
    Abstract: A composition for local application contains spermidine for the treatment of the stress urinary incontinence in a female subject. The composition is intended for transvaginal application to release spermidine onto external sphincter, urethra and endopelvic fascia, or for intravescial instillation. A variant composition takes the form of a condom lubricant comprising spermidine for the local release thereof during sexual intercourse, as an alternative or complementary to the local self-administration.
    Type: Application
    Filed: March 28, 2013
    Publication date: March 12, 2015
    Inventor: Carlo GHISALBERTI
  • Publication number: 20150050295
    Abstract: The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
    Type: Application
    Filed: February 12, 2014
    Publication date: February 19, 2015
    Applicant: AXOLABS GMBH
    Inventors: RAINER CONSTIEN, ANKE GEICK, PHILIPP HADWIGER, TORSTEN HANEKE, LUDGER MARKUS ICKENSTEIN, CARLA ALEXANDRA HERNANDEZ PRATA, ANDREA SCHUSTER, TIMO WEIDE
  • Publication number: 20150025276
    Abstract: A method for producing an organolithium compound includes the step of reacting an aromatic compound or a halogenated unsaturated aliphatic compound and a lithiating agent in the presence of a coordinating compound containing three or more elements having a coordinating ability in a molecule, at least one thereof being a nitrogen element, or a coordinating compound containing three or more oxygen elements having a coordinating ability in a molecule, at least one of the groups containing the oxygen elements having a coordinating ability being a tertiary alkoxy group, at a temperature of ?40° C. to 40° C.
    Type: Application
    Filed: October 3, 2014
    Publication date: January 22, 2015
    Applicant: Nippon Soda Co., Ltd.
    Inventor: Hiroki Inoue
  • Publication number: 20150025026
    Abstract: Campylobacter are the commonest reported bacterial causes of gastroenteritis in the UK and industrialized worlds. This invention relates to a method of preventing or reducing the colonisation of the gastrointestinal tract of an animal with Campylobacter. Accordingly, the present invention provides a method for disinfection of an animal comprising administering to said animal at least one compound that binds to MOMP or FlaA of Campylobacter in an effective amount to reduce the number of Campylobacter present in the gastrointestinal tract of said animal. The present invention also provides a method of preventing or reducing transmission of Campylobacter from one animal to another.
    Type: Application
    Filed: February 15, 2013
    Publication date: January 22, 2015
    Inventors: Jafar Mahdavi, Dlawer Ala'Aldeen
  • Publication number: 20150011645
    Abstract: Ion binding compounds and compositions may include compounds, polymers and compositions that include amine moieties. Ion binding polymers may be crosslinked amine polymers and may be used to remove ions, such as phosphate ions, from the gastrointestinal tract of animals, such as humans. Such compounds, polymers and compositions may be used therapeutically to treat a variety of medical conditions, such as hyperphosphatemia.
    Type: Application
    Filed: September 25, 2014
    Publication date: January 8, 2015
    Inventors: Stephen Randall HOLMES-FARLEY, Pradeep K. DHAL, Chad C. HUVAL
  • Publication number: 20150011640
    Abstract: A gynecologic composition contains spermidine to treat vulvar vestibulitis syndrome (VVS). In this therapeutic context, spermidine is effective at around one micromole per applied dose in the form of a simple salt or complex, alone or in combination or in conjunction with auxiliary actives such as anaesthetics and estrogens.
    Type: Application
    Filed: March 5, 2013
    Publication date: January 8, 2015
    Inventor: Carlo GHISALBERTI
  • Patent number: 8912362
    Abstract: Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: December 16, 2014
    Assignee: Philera New Zealand Limited
    Inventors: Marco Jonas, Irene Vaulont, Antonio Soi, Gunther Schmidt
  • Patent number: 8901355
    Abstract: Provided are new dendrimers and processes for making them. The dendrimers are derived from a nitroalkyloxirane compound of formula (III): wherein R1, R2, and R3 are as described herein.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: December 2, 2014
    Assignees: Dow Global Technologies LLC, ANGUS Chemical Company
    Inventors: Ian A. Tomlinson, Asghar A. Peera
  • Patent number: 8871304
    Abstract: The present invention relates to an (amide amino alkane) metal compound represented by the formula (1): wherein M represents a metal atom; R1 represents a linear, branched or cyclic alkyl group having 1 to 6 carbon atoms; R2 and R3 may be the same as, or different from each other, and each independently represents a linear or branched alkyl group having 1 to 3 carbon atoms, or R2 and R3 may form a substituted or unsubstituted 5- or 6-membered ring together with the nitrogen atom to which they are bound; Z represents a linear or branched alkylene group having 1 to 10 carbon atoms (a part of which may optionally form a ring); and n represents a number of the ligands, which is equal to the valence of the metal (M), and represents an integer of from 1 to 3; with the proviso that the metal compounds in which M is Li (Lithium), Be (Beryllium), Ge (Germanium) or Nd (Neodymium) are excluded; the metal compounds in which M is Mg (Magnesium) and R1 is methyl group are excluded; the metal compounds in which M i
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: October 28, 2014
    Assignee: Ube Industries, Ltd.
    Inventors: Osamu Fujimura, Hiroki Kanato, Masashi Shirai, Hiroshi Nihei
  • Publication number: 20140309334
    Abstract: The present invention relates to curing agents for epoxy resins including an alkylated polyethyleneimine. These curing agents have high functionality and a high content of secondary amino groups. Together with epoxy resins, they cure surprisingly quickly and without blushing effects even under humid and cold conditions to form films having very high cross-linking density. They are suited for coatings with high resistance requirements.
    Type: Application
    Filed: November 8, 2012
    Publication date: October 16, 2014
    Inventors: Andreas Kramer, Urs Burckhardt, Ursula Stadelmann, Edis Kasemi
  • Publication number: 20140309460
    Abstract: Process for increasing the molar mass of polyalkylenepolyamines by homogeneously catalyzed alcohol amination, which comprises carrying out a reaction of the polyalkylenepolyamines in a reactor with elimination of water in the presence of a homogeneous catalyst and removing the water of reaction from the reaction system. Polyalkylenepolyamines obtainable by such processes, and polyalkylenepolyamines comprising hydroxyl groups, secondary amines or tertiary amines. Uses of such polyalkylenepolyamines as adhesion promoters for printing inks, adhesion promoters in composite films, cohesion promoters for adhesives, crosslinkers/curing agents for resins, primers for paints, wet-adhesion promoters for emulsion paints, complexing agents and flocculating agents, penetration assistants in wood preservation, corrosion inhibitors, immobilizing agents for proteins and enzymes.
    Type: Application
    Filed: November 19, 2012
    Publication date: October 16, 2014
    Applicant: BASF SE
    Inventors: Julia Strautmann, Thomas Schaub, Stephan Hueffer, Rocco Paciello
  • Patent number: 8853457
    Abstract: A method for producing a polyamine is described that provides excellent safety, a lot of flexibility regarding a variety of its productions, and that can produce a polyamine of high-molecular weight easily and inexpensively. The polyamine includes a combination of units of formula (1) or (2): —(NH—(CH2)m—NH—(CH2)n)—??(1) (in the formula (1), independently in every unit, “m” indicates an integral number of 0 or more and “n” indicates an integral number of 3 or more.) —(NH—y—NH —Z)—??(2) (in the formula (2), independently in every unit, “Y” and “Z” are the same as or different from each other, and they indicate substituted or unsubstituted groups including unsaturated aliphatic, cyclic aliphatic or aromatic hydrocarbon radicals that can include hetero atoms.).
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: October 7, 2014
    Assignee: Rhodia Operations
    Inventors: Hiroyuki Kitayama, Hironao Sajiki, Yasunari Monguchi
  • Publication number: 20140286927
    Abstract: A engineered composition and method of delivery of said composition providing effective therapy for the treatment of ulcerative colitis, and Crohn's disease.
    Type: Application
    Filed: June 19, 2012
    Publication date: September 25, 2014
    Inventor: Peter Edward Smith
  • Publication number: 20140275475
    Abstract: A process for preparing olefin-CO copolymers with the steps of: providing a reactor; charging the reactor with a gaseous olefin and with CO, such that there is a first pressure p1 in the reactor; and reacting olefin with CO in the presence of a catalyst in the reactor. Prior to the reaction, either no CO is present in the reactor or the volume ratio of gaseous olefin to CO is ?90:10. During the reaction, gaseous olefin and CO are metered in at least intermittently, with an average over time of the volume ratio of the olefin metered into CO metered in of ?90:10.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Applicant: Bayer Intellectual Property GmbH
    Inventors: Thomas Ernst Müller, Christoph Gürtler, Walter Leitner, Henning Vogt, Saeeda Soomro
  • Publication number: 20140271729
    Abstract: This invention relates to a composition, and methods of administration and treatment comprising a homeopathic preparation of an effective amount of Spermine and/or Spermidine that improves hormone imbalances in males and females. The purpose of the invention is to provide a homeopathic treatment comprising Spermine and/or Spermidine that demonstrates improvement in energy, sleep, sexual function, relief of prostrate symptoms, lighter and shorter hot flush symptoms, stamina, weight loss, and the overall mood and stress of a patient.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: Apotheca, Inc.
    Inventor: Jesse Rettig
  • Patent number: 8822729
    Abstract: A method for providing a secondary or tertiary amine with formula (R1R2NR3)2NR4 is provided, wherein each of R1 and R2 are chosen from the group consisting of a methyl group, an ethyl group, an iso-propyl group and an n-propyl group; R3 being an alkoxyalkyl group chosen from the group consisting of —CH2CH2OCH2CH2—, —CH2CH2OCH2CH2— and —CH2CH2CH2OCH2CH2CH2—; R4 is chosen from the group consisting of a hydrogen, a methyl group, an ethyl group, an iso-propyl group, an n-propyl group and a group with formula R1R2NR3. The method comprises the steps: (?) reacting R1R2NR3(OH) with ammonia, thereby providing a mixture comprising (R1R2NR3)2NR4; (?) separating (R1R2NR3)2NR4 from said mixture.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: September 2, 2014
    Assignees: Huntsman International LLC, Huntsman Corporation Hungary Zrt
    Inventors: Zsolt Gaspar, Heiko H. Humbert, Gabor Felber, Attila Gaspar, Robert A Grigsby, Jr., Imre Kordas, Petra Emma Vanderstraeten
  • Publication number: 20140243557
    Abstract: The present invention relates to polyamines and to a process for preparing polyamines.
    Type: Application
    Filed: February 26, 2014
    Publication date: August 28, 2014
    Applicant: BASF SE
    Inventors: Ansgar Gereon ALTENHOFF, Christoph MUELLER, Christian MUELLER, Andreas KUNST, Thomas REISSNER, Kirsten DAHMEN
  • Patent number: 8802896
    Abstract: Disclosed is a polyether compound which is useful as a curing agent or the like, a curing agent using the compound and a producing method of the compound. The polyether compound of the present invention is represented by the following general formula (1). (In the formula, R1 represents a hydrogen atom or a methyl group and R2 represents a hydrogen atom or —C(?O)—C(R3)?CH2. R3 represents a hydrogen atom or a methyl group. R1, R2 and R3 may be the same as or different from each other.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: August 12, 2014
    Assignee: FUJIFILM Corporation
    Inventors: Akihito Amao, Hirotaka Kitagawa
  • Patent number: 8765008
    Abstract: Provided is a hydroxyalkylated polyalkylene polyamine composition, and a method for preparing the composition at low cost. Further disclosed is a method for producing a polyurethane resin by using the hydroxyalkylated polyalkylene polyamine composition containing at least two hydroxyalkylated polyalkylene polyamines as defined herein.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: July 1, 2014
    Assignee: Tosoh Corporation
    Inventors: Takahiro Masuda, Yutaka Tamano
  • Publication number: 20140170175
    Abstract: The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
    Type: Application
    Filed: February 12, 2014
    Publication date: June 19, 2014
    Applicant: AXOLABS GMBH
    Inventors: RAINER CONSTIEN, ANKE GEICK, PHILIPP HADWIGER, TORSTEN HANEKE, LUDGER MARKUS ICKENSTEIN, CARLA ALEXANDRA HERNANDEZ PRATA, ANDREA SCHUSTER, TIMO WEIDE
  • Publication number: 20140171649
    Abstract: The invention features methods and compositions for the synthesis of multimerizing agents. An exemplary method for producing AP20187 may comprise: (a) coupling 2-N,Ndimethylaminomethyl-1,3-diaminopropane with AP20792 to produce the dimeric alcohol, AP20793; and (b) coupling the AP20793 so produced with API7362 to yield AP20187. In particular embodiments, the method further includes the step of producing API7362 by coupling API7360 with methyl-L-pipecolic acid, or a salt thereof.
    Type: Application
    Filed: January 26, 2012
    Publication date: June 19, 2014
    Applicant: ARIAD PHARMACEUTICALS, INC.
    Inventors: Feng Li, Yihan Wang
  • Publication number: 20140162934
    Abstract: The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
    Type: Application
    Filed: February 12, 2014
    Publication date: June 12, 2014
    Applicant: AXOLABS GMBH
    Inventors: Rainer CONSTIEN, Anke Geick, Philipp Hadwiger, Torsten Haneke, Ludger Markus Ickenstein, Carla Alexandra Hernandez Prata, Andrea Schuster, Timo Weide
  • Patent number: 8748661
    Abstract: The present invention relates to novel polyamino polyketide antibiotics, methods of their production as well as methods of using these antibiotics, for example, for inhibition or removal of biofilm formation or for treating bacterial infection with these antibiotics.
    Type: Grant
    Filed: November 9, 2009
    Date of Patent: June 10, 2014
    Assignee: Agency for Science, Technology and Research
    Inventors: Jien Wu, Haibao Zhang, Lianhui Zhang
  • Patent number: 8729204
    Abstract: Compositions and methods for producing polymerization initiators comprising at least two protected primary amine groups. Polymers prepared using such polymerization initiators can comprise a residue of the polymerization initiator and can initially comprise the at least two protected primary amine groups. Such polymers can undergo a deprotection process thereby yielding a polymer having one or more unprotected primary amine groups. Polymers having primary amine groups can be employed in rubber compositions, which have a variety of potential applications, such as, for example, in tire manufacturing.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: May 20, 2014
    Assignee: Bridgestone Corporation
    Inventors: Eiju Suzuki, Terrence E. Hogan
  • Publication number: 20140107068
    Abstract: A marker can determine whether or not a patient has a therapeutic response to an anti-cancer agent. A novel cancer therapy employs the marker. The marker can be N-acetylglucosamine, an amino-acid-metabolism-related substance, a nucleic-acid-metabolism-related substance, a substance in the pentose phosphate pathway, a substance in the glycolytic pathway, a substance in the TCA cycle, a polyamine-metabolism-related substance, lauric acid, 6-phosphogluconic acid, butyric acid, 4-methylpyrazole, isobutylamine, glycolic acid, NADH, NAD+, or a substance involved in the metabolism of any of these substances.
    Type: Application
    Filed: February 24, 2012
    Publication date: April 17, 2014
    Applicants: KABUSHIKI KAISHA YAKULT HONSHA, KEIO UNIVERSITY
    Inventors: Yusuke Tanigawara, Akito Nishimuta, Yuki Otani, Mitsuhisa Matsuo
  • Publication number: 20140057877
    Abstract: This invention relates to a process of synthesis and composition of open chain (ring), closed ring, linear branched and or substituted polyamines, polyamine derived tyrosine phosphatase inhibitors and PPAR partial agonists/partial antagonists via a series of substitution reactions and optimizing the bioavailability and biological activities of the compounds. Polyamines prevent the toxicity of neurotoxins and diabetogenic toxins including paraquat, methyphenyl pyridine radical, rotenone, diazoxide, streptozotocin and alloxan.
    Type: Application
    Filed: October 18, 2011
    Publication date: February 27, 2014
    Inventors: Michael A. Murphy, Mitchell R. Malachowski
  • Patent number: 8658829
    Abstract: A method of preparing polyalkylated oligoalkylenepolyamines is provided. The method includes contacting oligoalkylenepolyamine with a reagent composition comprising (a) alkyl bromide and/or alkyl chloride; (b) a basic agent; and (c) iodide salt. The alkylation reaction may be carried out in a polar, aprotic organic solvent.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: February 25, 2014
    Assignee: NDSU Research Foundation
    Inventor: Arumugasamy Elangovan
  • Publication number: 20130345311
    Abstract: Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.
    Type: Application
    Filed: January 25, 2013
    Publication date: December 26, 2013
    Applicant: PHILERA NEW ZEALAND LIMITED
    Inventor: PHILERA NEW ZEALAND LIMITED
  • Patent number: 8609900
    Abstract: The present invention is in relation to a dendritic molecule having symmetrically sited branches having four or more generations of dendrimers wherein the branch points are tertiary amines linked together with oxygen atom of ether and the heteroatoms are separated by a substituted or non-substituted linear three methylene linker. In addition the invention also provides a process to prepare such dendritic macromolecules.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: December 17, 2013
    Assignee: Indian Institute of Science
    Inventors: Jayaraman Narayanaswamy, Jayamurugan Govindasamy
  • Publication number: 20130303805
    Abstract: The present invention relates to a process for producing an amino compound by subjecting a polyamine and an alkenyl compound to addition reaction in the presence of an alkali metal hydride compound which is capable of supplying the amino compound in a stable manner without occurrence of odor.
    Type: Application
    Filed: January 16, 2012
    Publication date: November 14, 2013
    Applicant: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hisayuki Kuwahara, Tomotaka Wada
  • Publication number: 20130273250
    Abstract: The present invention relates to an (amide amino alkane) metal compound represented by the formula (1): wherein M represents a metal atom; R1 represents a linear, branched or cyclic alkyl group having 1 to 6 carbon atoms; R2 and R3 may be the same as, or different from each other, and each independently represents a linear or branched alkyl group having 1 to 3 carbon atoms, or R2 and R3 may form a substituted or unsubstituted 5- or 6-membered ring together with the nitrogen atom to which they are bound; Z represents a linear or branched alkylene group having 1 to 10 carbon atoms (a part of which may optionally form a ring); and n represents a number of the ligands, which is equal to the valence of the metal (M), and represents an integer of from 1 to 3; with the proviso that the metal compounds in which M is Li (Lithium), Be (Beryllium), Ge (Germanium) or Nd (Neodymium) are excluded; the metal compounds in which M is Mg (Magnesium) and R1 is methyl group are excluded; the metal compounds in which M i
    Type: Application
    Filed: November 2, 2011
    Publication date: October 17, 2013
    Applicant: UBE INDUSTRIES, LTD
    Inventors: Osamu Fujimura, Hiroki Kanato, Masashi Shirai, Hiroshi Nihei
  • Publication number: 20130267709
    Abstract: Methods for deposition of elemental metal films on surfaces using metal coordination complexes comprising bisamineazaallylic ligands are provided. Also provided are bisamineazaallylic ligands useful in the methods of the invention and metal coordination complexes comprising these ligands.
    Type: Application
    Filed: June 3, 2013
    Publication date: October 10, 2013
    Inventors: David Thompson, Jeffrey W. Anthis
  • Patent number: 8541622
    Abstract: This invention provides novel compositions comprising substituted polyamines as acid gas scrubbing solutions and methods of using the compositions in an industrial system. The invention relates to the use of such polyamine compounds in industrial processes to remove acidic contaminants from natural and industrial fluid streams, such as natural gas, combustion gas, natural gas, synthesis gas, biogas, and other industrial fluid streams. The compositions and methods of the invention are useful for removal, absorption, or sequestration of acidic contaminants and sulfide contaminants including CO2, H2S, RSH, CS2, COS, and SO2.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: September 24, 2013
    Assignee: Nalco Company
    Inventors: Alan M. Blair, Keith N. Garside, William J. Andrews, Kailas B. Sawant
  • Publication number: 20130137901
    Abstract: Process for the preparation of polyalkylenepolyamines by homogeneously catalyzed alcohol amination, in which aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst and in the presence of hydrogen gas. Polyalkylenepolyamines obtainable by such processes and polyalkylenepolyamines comprising hydroxy groups, secondary amines or tertiary amines. Uses of such polyalkylenepolyamines as adhesion promoters for printing inks, adhesion promoters in composite films, cohesion promoters for adhesives, crosslinkers/curing agents for resins, primers for paints, wet-adhesion promoters for emulsion paints, complexing agents and flocculating agents, penetration assistants in wood preservation, corrosion inhibitors, immobilizing agents for proteins and enzymes.
    Type: Application
    Filed: November 19, 2012
    Publication date: May 30, 2013
    Inventors: Julia STRAUTMANN, Thomas Schaub, Stephan Hueffer, Steffen Maas, Rocco Paciello
  • Publication number: 20130137772
    Abstract: A salt of a polyamine having the formula: with a pharmaceutically acceptable organic or inorganic acid, wherein at least one of the bridging groups ALK1, ALK2 and ALK3 contains at least one —CH(OH)-group which is not alpha- to any of the nitrogen atoms.
    Type: Application
    Filed: November 29, 2011
    Publication date: May 30, 2013
    Inventor: Raymond J. Bergeron
  • Publication number: 20130123542
    Abstract: A method for producing a polyamine is described that provides excellent safety, a lot of flexibility regarding a variety of its productions, and that can produce a polyamine of high-molecular weight easily and inexpensively. The polyamine includes a combination of units of formula (1) or (2): —(NH—(CH2)m—NH—(CH2)n)—??(1) (in the formula (1), independently in every unit, “m” indicates an integral number of 0 or more and “n” indicates an integral number of 3 or more.) —(NH—Y—NH—Z)—??(2) (in the formula (2), independently in every unit, “Y” and “Z” are the same as or different from each other, and they indicate substituted or unsubstituted groups including unsaturated aliphatic, cyclic aliphatic or aromatic hydrocarbon radicals that can include hetero atoms.).
    Type: Application
    Filed: December 17, 2010
    Publication date: May 16, 2013
    Applicant: RHODIA OPERATIONS
    Inventors: Hiroyuki Kitayama, Hironao Sajiki, Yasunari Monguchi
  • Patent number: 8440852
    Abstract: The invention relates to a process for preparing tetraethylenepentamine (TEPA) by hydrogenation of diethylenetriaminediacetonitrile (DETDN) over a catalyst. If appropriate, DETDN can also be present as a constituent of an amino nitrile mixture which additionally comprises diethylenetriaminemonoacetonitrile (DETMN).
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: May 14, 2013
    Assignee: BASF SE
    Inventors: Kirsten Dahmen, Alfred Oftring, Randolf Hugo, Thilo Hahn, Katrin Baumann, Johann-Peter Melder
  • Patent number: 8426338
    Abstract: The invention describes a method and product for chelating micronutrients when used to provide the micronutrients to a plant, which comprises applying to an area of the plant or soil/substrate surrounding the plant an effective amount of a plant fertiliser composition comprising a chelating polymer having the general formula (I), capable of forming coordinate bonds with the micronutrients, transporting the micronutrients across a membrane of the plant and releasing the micronutrients for use by the plant.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: April 23, 2013
    Assignee: Adelaide Research and Innovation Pty Ltd
    Inventors: Mike McLaughlin, Samuel Stacey, Enzo Lombi
  • Patent number: 8394992
    Abstract: Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: March 12, 2013
    Assignee: PhilEra New Zealand Limited
    Inventors: Marco Jonas, Irene Vaulont, Antonio Soi, Gunther Schmidt
  • Publication number: 20130059852
    Abstract: Some embodiments of this invention include methods for treating disease and methods for administering a compound of Formula (I). In some aspects of the invention, diseases can be treated by administration of compositions comprising a compound of Formula (I). Pharmaceutical compositions of some embodiments of the present invention comprise a compound of Formula (I).
    Type: Application
    Filed: April 8, 2011
    Publication date: March 7, 2013
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: John O. Trent, Jason B. Meier, Kelby B. Napier
  • Publication number: 20130053374
    Abstract: The present invention provides an ophthalmic composition comprising a hyperbranched polyester. The ophthalmic compositions may also comprise carbonic anhydrase inhibitors, wherein the hyperbranched polyester increases the aqueous solubility of the carbonic anhydrase inhibitor, and increases corneal permeation of the active agent. The ophthalmic compositions may also comprise non-ionic surfactants, such as PEG, Polysorbate, HPMC or HEC, and beta-blockers, such as Carteolol, Levobunolol, Betaxolol, Metipranolol, Timolol or Propranolol. The concentration of the hyperbranched polyester in the ophthalmic formulation should be less than or equal to 4% (w/v) in order to avoid any cytotoxic effects on human corneal cells and thus the eye irritation.
    Type: Application
    Filed: May 4, 2011
    Publication date: February 28, 2013
    Inventors: Jun Inoue, Tapan Shah
  • Patent number: 8361426
    Abstract: Absorption medium for acid gases comprising an oligoamine (A) of the general formula (I) and a piperazine derivative (B) of the general formula (II) in which the weight ratio of oligoamine (A) to the piperazine derivative (B) is 0.2 to 25, and also process for removing acid gases from a gas stream by contacting the gas stream at a pressure of 0.05 to 10 MPa abs with an aqueous solution of said absorption medium which is brought to and maintained at a temperature of 20 to 80° C.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: January 29, 2013
    Assignee: BASF SE
    Inventors: Ute Lichtfers, Robin Thiele, Susanna Voges, Georg Sieder, Oliver Spuhl, Hugo Rafael Garcia Andarcia
  • Publication number: 20130011916
    Abstract: Nucleic acids comprising a nucleic acid moiety and two or more transfection enhancer elements (TEE's) according to the general formula (I): Hydrophobic moiety—pH-responsive hydrophilic moiety, wherein said pH sensitive hydrophilic moiety of said TEE is independently a weak acid having a pka of between 4 and 6.5 or is a zwitterionic structure comprising a combination of acidic groups with weak basis having a pKa of between 4.5 and 7.
    Type: Application
    Filed: April 30, 2012
    Publication date: January 10, 2013
    Applicant: Lipocalyx GmbH
    Inventor: Steffen Panzner