Boron Containing (e.g., Boron Containing Complexes, Salts, Etc.) Patents (Class 564/8)
  • Publication number: 20080132678
    Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.
    Type: Application
    Filed: January 2, 2008
    Publication date: June 5, 2008
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Julian Adams, Yu-Ting Ma, Ross L. Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
  • Publication number: 20080102279
    Abstract: A borate for a near-infrared ray absorption material, having an anion represented by the formula (1): [BR1mR24?m]? (wherein R1 represents an aryl group having an electron withdrawing group; R2 represents an organic group, a halogen group or a hydroxyl group; and m is an integer in the range of 1 to 4) is provided. The borate of the present invention enables to improve durability, in particular, heat resistance and moisture resistance of a near-infrared ray absorbing dye.
    Type: Application
    Filed: January 30, 2006
    Publication date: May 1, 2008
    Applicant: NIPPON SHOKUBAI CO., LTD.
    Inventors: Akio Ito, Satoshi Ishida, Toshiya Iida, Takako Ishii, Nobuhiro Nobayashi
  • Patent number: 7232928
    Abstract: Cycloalkanone oxime is stabilized by a method comprising bringing the cycloalkanone oxime into contact with at least one compound selected from the group consisting of oxoacids, oxoacid salts, oxoacid esters, oxoacid amides and oxides of boron or phosphorus. In accordance with the invention, the thermal stability of cycloalkanone oxime can be improved.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: June 19, 2007
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Masami Fukao, Noriaki Tanaka
  • Patent number: 7196219
    Abstract: A process for preparing anilineboronic acid derivative of the formula I, by converting an aniline to a diprotected aniline by introducing two protecting groups, metalating the diprotected aniline with a metalating agent and simultaneously or subsequently reacting with a boronic ester B(OR1,2,3)3 to form a protected anilineboronic ester, which is converted, by detaching the protecting groups, to the anilineboronic esters of the formula (I).
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: March 27, 2007
    Assignee: Archimica GmbH
    Inventors: Stefan Scherer, Andreas Meudt, Bernd Lehnemann, Alexei Kalinin, Victor Snieckus
  • Patent number: 7157399
    Abstract: In one embodiment the invention is a polymerizable composition comprising a) an organoborane amine complex; b) one or more of monomers, oligomers or polymers having olefinic unsaturation which is capable of polymerization by free radical polymerization; c) one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization; and d) a catalyst for the polymerization of the one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization. This composition may further comprise a compound which causes the organoborane amine complex to disassociate.
    Type: Grant
    Filed: June 9, 2004
    Date of Patent: January 2, 2007
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Benjamin L. Wendt, Daniel R. Harrington
  • Patent number: 7101940
    Abstract: The invention relates to a chemical compound of formula (I), wherein M1 represents an element selected from main groups II, III or IV of the periodic table of elements; x is equal to 1, 2, 3 or 4; y is equal to 2, 3 or 4, and; A represents a cation of main group V of the periodic table of elements; R1 is the same or different and represents a branched or unbranched linear or cyclic C1–C40 group that contains carbon; R2 is the same or different and represents a branched or unbranched linear or cyclic C1–C40 group that contains carbon; R3 represents a branched or unbranched linear or cyclic C1–C40 group that contains carbon, and; R4 represents a hydrogen atom; whereby R2 and R3 are always different from one another
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: September 5, 2006
    Assignee: Basell Polyolefine GmbH
    Inventors: Jörg Schottek, Heike Gregorius, David Fischer, Iris Kuellmer
  • Patent number: 7078554
    Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: July 18, 2006
    Assignee: Sensors for Medicine and Science, Inc.
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik
  • Patent number: 7045652
    Abstract: The invention relates to processes for preparing a compound of the formula (V) and alkyl boronic esters thereof wherein R1 is attached at the 2 or 3 position of the benzene ring, R2 is attached at the 5 or 6 position, and R1, R2 and G are as defined herein. Said compound is a key synthetic intermediate in the preparation of 2-amino-6-(substituted-4-phenoxy)-substituted-pyridines useful as nitric oxide synthase (NOS) inhibitors in a mammal.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: May 16, 2006
    Assignee: Pfizer INC
    Inventors: Stephane Caron, Jolanta Nowakowski
  • Patent number: 6919036
    Abstract: A family of borate compounds containing an isolated (finite) nonaborate anion with the structural formula [B9O12(OH)6]3?. Preferred amine nonaborate compounds have a resolved oxide formula of A2O.3B2O3.2H2O, where A is the monovalent cation of an amine salt, such as guanidinium and imidazolium. Also provided is a method for preparing these compounds by crystallization from an aqueous solution under mild conditions without the formation of significant amounts of by-products. These compounds have potential application as precursors for the production of advanced boron nitride ceramic materials, and as flame retardants, corrosion inhibitors, and biocides.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: July 19, 2005
    Assignee: U.S. Borax Inc.
    Inventor: David M. Schubert
  • Publication number: 20040242812
    Abstract: In one embodiment the invention is a polymerizable composition comprising a) an organoborane amine complex; b) one or more of monomers, oligomers or polymers having olefinic unsaturation which is capable of polymerization by free radical polymerization; c) one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization; and d) a catalyst for the polymerization of the one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization. This composition may further comprise a compound which causes the organoborane amine complex to disassociate.
    Type: Application
    Filed: June 9, 2004
    Publication date: December 2, 2004
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Benjamin L. Wendt, Daniel R. Harrington
  • Publication number: 20040210015
    Abstract: In one embodiment the invention is a polymerizable composition comprising a) an organoborane amine complex; b) one or more of monomers, oligomers or polymers having olefinic unsaturation which is capable of polymerization by free radical polymerization; c) one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization; and d) a catalyst for the polymerization of the one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization. This composition may further comprise a compound which causes the organoborane amine complex to disassociate.
    Type: Application
    Filed: June 1, 2004
    Publication date: October 21, 2004
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Benjamin L. Wendt, Daniel R. Harrington
  • Patent number: 6777512
    Abstract: In one embodiment the invention is a polymerizable composition comprising a) an organoborane amine complex; b) one or more of monomers, oligomers or polymers having olefinic unsaturation which is capable of polymerization by free radical polymerization; c) one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization; and d) a catalyst for the polymerization of the one or more compounds, oligomers or prepolymers having a siloxane backbone and reactive moieties capable of polymerization. This composition may further comprise a compound which causes the organoborane amine complex to disassociate.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: August 17, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Benjamin L. Wendt, Daniel R. Harrington
  • Patent number: 6762260
    Abstract: The invention is a two part polymerizable composition comprising in one part an organoborane amine complex and one or more compounds containing ring opening heterocyclic moieties, and in a second part, compounds capable of being polymerized by free radical polymerization, a catalyst capable of polymerizing compounds containing ring opening heterocyclic moieties and optionally a component that will decomplex the organoborane amine complex. In one embodiment the invention is a two phase system comprising a first phase containing one or more polymers prepared from the compounds which polymerize by free radical polymerization and a second phase comprising polymerized or partially polymerized compounds derived from one or more compounds containing ring opening heterocyclic moieties.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: July 13, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Benjamin L. Wendt, Daniel D. Harrington
  • Patent number: 6730759
    Abstract: The invention is polymerizable composition comprising a) an organoborane/amine complex wherein the organoborane is a trialkyl borane or an alkyl cycloalkyl borane and the amine is selected from the group of amines having an amidine structural component; aliphatic heterocycles having at least one nitrogen in the heterocyclic ring; an alicyclic compound having bound to the ring a substituent having an amine moiety; primary amines which in addition to a primary amine have one or more hydrogen bond accepting groups of an ether, polyether, thioether or halogen wherein there is an alkylene chain of at least two carbon atoms between the primary amine and the hydrogen bond accepting group, and conjugated imines; and, b) one or more of monomers, oligomers or polymers having olefinic unsaturation; and optionally c) an effective amount of a compound which causes the complex to disassociate wherein the compound which causes disassociation of the complex is kept separate from the complex until initiation of polymerizat
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: May 4, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Nelson G. Rondan
  • Patent number: 6713566
    Abstract: This invention relates to a process for covalently coupling organic compounds which comprises: reacting an olefinic compound having at least one carbon to carbon double bond or an acetylenic compound having at least one carbon to carbon triple bond with a diboron derivative in the presence of a Group 8-11 metal catalyst to form an organoboron intermediate having an organoboronate residue on at least one carbon atom of the respective double or triple bond; and reacting the organoboron intermediate with an organic compound having a halogen or halogen-like substituent at a coupling position in the presence of a Group 8-11 metal catalyst and a suitable base, whereby the olefinic or acetylenic compound is coupled to the organic compound via a direct bond between the carbon atom having the organoboronate residue and the coupling posiitijno.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: March 30, 2004
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Sebastian Mario Marcuccio, Mary Rodopoulos, Helmut Weigold, Peter Osvath
  • Patent number: 6713579
    Abstract: A method of modifying the surface of a low surface energy polymer by contacting the surface with a composition comprising a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic heterocycles having at least one nitrogen in the heterocyclic ring; an alicyclic compound having bound to the ring a substituent having an amine moiety; amines which in addition to a primary amine have one or more hydrogen bond accepting groups of an ether, polyether, thioether or halogen wherein there is an alkylene chain of at least two carbon atoms between the primary amine and the hydrogen bond accepting group, and conjugated imines; b) one or more of monomers, oligomers or polymers having olefinic unsaturation; and optionally, c) an effective amount of a compound which causes the complex to disassociate.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: March 30, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Nelson G. Rondan
  • Patent number: 6713578
    Abstract: A method of bonding two or more substrates together which comprises I. contacting the components of the composition comprising a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic heterocycles having at least one nitrogen in the heterocyclic ring; an alicyclic compound having bound to the ring a substituent having an amine moiety; primary amines which in addition to a primary amine have one or more hydrogen bond accepting groups of an ether, polyether, thioether or halogen wherein there is an alkylene chain of at least two carbon atoms between the primary amine and the hydrogen bond accepting group, and conjugated imines; b) one or more of monomers, oligomers or polymers having olefinic unsaturation; and, c) optionally an effective amount of a compound which causes the complex to disassociate or heating the composition to a temperature at which the complex dissassociates; II.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: March 30, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Nelson G. Rondan
  • Patent number: 6710145
    Abstract: A method of coating a substrate which comprises coating a substrate with the composition comprising a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic heterocycles having at least one nitrogen in the heterocyclic ring; an alicyclic compound having bound to the ring a substituent having an amine moiety; primary amines which in addition to a primary amine have one or more hydrogen bond accepting groups of an ether, polyether, thioether or halogen wherein there is an alkylene chain of at least two carbon atoms between the primary amine and the hydrogen bond accepting group, and conjugated imines; b) one or more of monomers, oligomers or polymers having olefinic unsaturation, and c) an effective amount of a compound which causes the complex to disassociate; together under conditions such that polymerization is initiated.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: March 23, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Nelson G. Rondan
  • Patent number: 6706831
    Abstract: The invention is a method of polymerization comprising contacting the components of the polymerizable composition of a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic heterocycles having at least one nitrogen in the heterocyclic ring; an alicyclic compound having bound to the ring a substituent having an amine moiety; primary amines which in addition to a primary amine have one or more hydrogen bond accepting groups of an ether, polyether, thioether or halogen wherein there is an alkylene chain of at least two carbon atoms between the primary amine and the hydrogen bond accepting group; and conjugated imines; b) one or more of monomers, oligomers or polymers having olefinic unsaturation; and c) in the presence of an effective amount of a compound which causes the complex to disassociate or at a temperature at which causes the complex to disassociate.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: March 16, 2004
    Assignee: Dow Global Technologies Inc.
    Inventors: Mark F. Sonnenschein, Steven P. Webb, Nelson G. Rondan
  • Publication number: 20040038127
    Abstract: The present invention is directed to the use of a new ambient temperature molten salt as an electrolyte for electrochemical energy storage devices, such as electrochemical cells and electrolytic capacitors. The ambient temperature molten salt comprises an imide cation combined with a small anion. A particularly preferred anion is bis-trifluoromethanesulfonyl imide. The electrolyte is useful with electrochemical devices such as primary and secondary electrochemical cells and capacitors of the electrolytic and electrolytic/electrochemical hybrid types.
    Type: Application
    Filed: August 15, 2003
    Publication date: February 26, 2004
    Inventor: Carl Roger Schlaikjer
  • Publication number: 20030109751
    Abstract: A family of borate compounds containing an isolated (finite) nonaborate anion with the structural formula [B9O12(OH)6]3−. Preferred amine nonaborate compounds have a resolved oxide formula of A2O.3B2O3.2H2O, where A is the monovalent cation of an amine salt, such as guanidinium and imidazolium. Also provided is a method for preparing these compounds by crystallization from an aqueous solution under mild conditions without the formation of significant amounts of by-products. These compounds have potential application as precursors for the production of advanced boron nitride ceramic materials, and as flame retardants, corrosion inhibitors, and biocides.
    Type: Application
    Filed: July 19, 2002
    Publication date: June 12, 2003
    Inventor: David M Schubert
  • Publication number: 20030055286
    Abstract: 1 This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
    Type: Application
    Filed: September 5, 2002
    Publication date: March 20, 2003
    Inventors: Katherine Louisa Widdowson, Qi Jin
  • Publication number: 20030050493
    Abstract: This invention provides an anionic borate ligand, and its synthesis. Zwitterionic complexes formed by the ligand and a metal, and Group 9 and 10 metals in particular, are described. Uses of the complexes in stoichiometric and catalytic reaction chemistry are also provided.
    Type: Application
    Filed: March 28, 2002
    Publication date: March 13, 2003
    Inventors: Jonas C. Peters, John C. Thomas, Connie Lu, Theodore A. Betley
  • Publication number: 20030013913
    Abstract: The invention relates to a chemical compound of formula (I), wherein M1 represents an element selected from main groups II, III or IV of the periodic table of elements; x is equal to 1, 2, 3 or 4; y is equal to 2, 3 or 4, and; A represents a cation of main group V of the periodic table of elements; R1 is the same or different and represents a branched or unbranched linear or cyclic C1-C40 group that contains carbon; R2 is the same or different and represents a branched or unbranched linear or cyclic C1-C40 group that contains carbon; R3 represents a branched or unbranched linear or cyclic C1-C40 group that contains carbon, and; R4 represents a hydrogen atom; whereby R2 and R3 are always different from one another.
    Type: Application
    Filed: June 24, 2002
    Publication date: January 16, 2003
    Inventors: Joerg Schottek, Heike Gregorius, David Fischer, Iris Kuellmer
  • Publication number: 20030003038
    Abstract: Pocesses for synthesizing borohydride compounds with reduced energy requirements are disclosed.
    Type: Application
    Filed: April 12, 2001
    Publication date: January 2, 2003
    Inventors: Steven C. Amendola, Michael T. Kelly, Ying Wu
  • Publication number: 20020198394
    Abstract: The present invention provides weakly coordinating anion salts comprising a reactive cation and uses thereof. In particular, the present invention provides compounds of the formula MxQy and uses thereof, where M, Q, x, and y are those defined herein.
    Type: Application
    Filed: July 25, 2002
    Publication date: December 26, 2002
    Applicant: Colorado State University Research Foundation (CSURF)
    Inventors: Steven H. Strauss, Sergei V. Ivanov
  • Patent number: 6444846
    Abstract: There is provided a process for preparing tetraalkyl ammonium halide utilizing a catalytic amount of acetonitrile in a reaction under pressure and at an elevated temperature of an alkyl halide and a trialkyl halide and in which tetrafluoroborate can be subsequently prepared.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: September 3, 2002
    Assignee: Lithdyn International
    Inventors: W. Novis Smith, Joel McCloskey
  • Patent number: 6423251
    Abstract: Aqueous urea condensate-boron oxyacid salts composition may be utilized to fight grass, forest, building, and other flammable organic material by applying it to these flammable organic materials. The solid or aqueous urea condensate-boron oxyacid salts composition may also be incorporated into flammable materials such as solid and foam plastic and natural materials. Urea condensate-boron oxyacid salts composition may also contain carbonization auxiliaries, such as phosphorus containing compounds, metal containing compounds that will accelerate carbonization, heat reflector, surfactant and fillers. The urea condensate-boron oxyacid salts composition is produced by mixing, heating and/or reacting urea, boron oxyacids and alkali metal hydroxide or alkaline earth metal hydroxide or oxide or the boron oxyacids maybe first reacted with the alkali metal hydroxide or the alkaline earth metal oxide or hydroxide.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: July 23, 2002
    Inventor: David H. Blount
  • Publication number: 20020065433
    Abstract: The present invention is related to diimino compounds of formulae (I) R2—N═C(R1)(R3)nC(R1)═N—R2 and (II) (R1)2C═N—(CR24)m—N═C(R1)2 functionalized with at least one siloxy group. Said diimino compounds are useful for obtaining a solid catalyst component for polymerizing olefins wherein the diimino compound of formulae (I) or (II) is bonded to a porous inorganic support and to a transition metal selected from groups 8, 9 and 10 of the periodic table. This invention also relates to a process for preparing said diimino compounds of formulae (I) or (II), to a process for obtaining said solid catalyst component comprising the combination of the diimino compound and a porous inorganic support. Further, the invention also relates to the use of said solid catalyst in combination with a cocatalyst to polimerize olefins.
    Type: Application
    Filed: March 12, 2001
    Publication date: May 30, 2002
    Applicant: REPSOL QUIMICA S.A.
    Inventors: Luis Mendez Llatas, Antonio Munoz-Escalona Lafuente, Juan Campora Perez, Ernesto Carmona Guzman, Manuel Lopez Reyes
  • Patent number: 6388138
    Abstract: A solution comprising a halomagnesium tetrakis(Faryl)borate in a liquid organic medium, wherein the liquid organic medium is comprised of one or more liquid dihydrocarbyl ethers, one or more liquid hydrocarbons, one or more liquid halogenated hydrocarbons, or mixtures thereof, is contacted with water. This produces magnesium di[tetrakis(Faryl)borate] in the organic phase of a two-phase water/liquid organic medium. The magnesium di[tetrakis(Faryl)borate] can be, but need not be, isolated. A protic ammonium salt, an onium salt, or a triarylmethyl salt can be reacted with the magnesium di[tetrakis(Faryl)borate] to produce the corresponding protic ammonium, onium, or triarylmethyl tetrakis(Faryl)borate. The magnesium di[tetrakis(Faryl)borate] can instead be reacted with a metal salt to form a metal tetrakis(Faryl)borate.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: May 14, 2002
    Assignee: Albemarle Corporation
    Inventor: John Y. Lee
  • Patent number: 6384165
    Abstract: A composition comprises organoborane amine complex and 1,4-dioxo-2-butene-functional material. The composition can form a part of a polymerization initiator system that also includes a compound that is reactive with the amine portion of the complex. The system can be used to initiate polymerization of acrylic monomer and to form an acrylic adhesive that has exceptionally good adhesion to low surface energy polymers.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: May 7, 2002
    Assignee: 3M Innovative Properties Co.
    Inventor: Dean M. Moren
  • Publication number: 20020040116
    Abstract: A composition comprises organoborane amine complex and 1,4-dioxo-2-butene-functional material. The composition can form a part of a polymerization initiator system that also includes a compound that is reactive with the amine portion of the complex. The system can be used to initiate polymerization of acrylic monomer and to form an acrylic adhesive that has exceptionally good adhesion to low surface energy polymers.
    Type: Application
    Filed: February 15, 2001
    Publication date: April 4, 2002
    Applicant: 3M Innovative Properties Company
    Inventor: Dean M. Moren
  • Patent number: 6344529
    Abstract: Disclosed are compounds useful as catalyst activators for olefin polymerization, comprising structures of the following formulae: wherein: L+ is a protonated derivative of an element of Group 15 of the Periodic Table of the Elements, additionally bearing two hydrocarbyl substituents of from 1 to 50 carbons each, or a positively charged derivative of an element of Group 14 of the Periodic Table of the Elements, said Group 14 element being substituted with three hydrocarbyl substituents of from 1 to 50 carbons each; R1 is a divalent linking group of from 1 to 40 non-hydrogen atoms; R2 independently each occurrence is a ligand group of from 1 to 50 nonhydrogen atoms with the proviso that in a sufficient number of occurrences to balance charge in the compound, R2 is L+—R1—; M1 is boron, aluminum or gallium; Arf independently each occurrence is a monovalent, fluorinated organic group containing from 6 to 100 non-hydrogen atoms; Y is a Group 15 element; and Z is a Grou
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: February 5, 2002
    Assignee: The Dow Chemical Company
    Inventors: Edmund M. Carnahan, Grant B. Jacobsen, Jerzy Klosin, Peter N. Nickias, David J. Schwartz, David R. Neithamer
  • Patent number: 6252023
    Abstract: A composition comprises organoborane amine complex and 1,4-dioxo-2-butene-functional material. The composition can form a part of a polymerization initiator system that also includes a compound that is reactive with the amine portion of the complex. The system can be used to initiate polymerization of acrylic monomer and to form an acrylic adhesive that has exceptionally good adhesion to low surface energy polymers.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: June 26, 2001
    Assignee: 3M Innovative Properties Company
    Inventor: Dean M. Moren
  • Patent number: 6140537
    Abstract: A method of producing a boron-based compound represented by general formula (1) including a first step of reacting lithium, magnesium or a compound containing lithium, a compound represented by general formula (2), and a compound represented by general formula (3): R.sup.2 --Y to produce a borate metal salt represented by general formula (4), and a second step of adding to the borate metal salt an onium halide represented by general formula (5): Z.sup.+ .multidot.X.sup.- to effect ion exchange reaction (the symbols in the formulae have the same meanings as described in the specification).According to the production method of the present invention, a high purity boron-based compound represented by the general formula (1) above useful as a photopolymerization initiator and a light-absorbing decolorizing agent can be obtained in a short time and a high yield as compared with the conventional method.
    Type: Grant
    Filed: August 5, 1999
    Date of Patent: October 31, 2000
    Assignee: Showa Denko K.K.
    Inventors: Tsuyoshi Katoh, Morihiko Yamada
  • Patent number: 6130357
    Abstract: The present invention provides compounds comprising a polyhalogenated heteroborane anion of the formula R.sub.a ZB.sub.b H.sub.c F.sub.d X.sub.e (OR").sub.f.sup.-1, and a method for producing the same. Specifically, the present invention provides compounds comprising a polyfluorinated monocarborane anion.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 10, 2000
    Assignee: Colorado State University Research Foundation
    Inventors: Steven H. Strauss, Sergei V. Ivanov, Anthony J. Lupinetti
  • Patent number: 6117852
    Abstract: The present invention discloses a boron-containing pharmaceutical composition useful in boron neutron capture therapy of hepatoma, which includes lipiodol, stibmicron boron powder, lecithin and unsaturated fatty acid. The lipiodol has a property of a high retention in hepatoma, the lecithin has a boron carrying capacity, and the unsaturated fatty acid has a function of rendering lecithin soluble in lipiodol.
    Type: Grant
    Filed: December 29, 1997
    Date of Patent: September 12, 2000
    Assignee: National Science Council
    Inventor: Fong-In Chou
  • Patent number: 6060623
    Abstract: A process for producing an amine borane compound, comprising the steps of:reacting an amine salt with sodium borohydride in an organic solvent,distilling off the organic solvent to thereby obtain a distillation residue,adding an aqueous alkali hydroxide solution to the distillation residue to thereby form an organic phase and a water phase,fractionating the organic phase, anddistilling off the organic solvent from the organic phase. This process is advantageous in terms of cost and ensures safe work environment because the aqueous alkali hydroxide solution is used in place of an organic solvent in the purification (recrystallization) of the amine borane compound. Moreover, the decomposition of the amine borane compound is suppressed by the addition of the aqueous alkali hydroxide solution.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: May 9, 2000
    Assignee: Shiroi Yakuhin Co., Ltd.
    Inventor: Yoshiaki Iwasaki
  • Patent number: 6011180
    Abstract: Compounds of the formula I ##STR1## in which R.sub.1 is, for example, C.sub.1 -C.sub.20 alkyl or phenyl-C.sub.1 -C.sub.6 alkyl which radicals are unsubstitutedor substituted; R.sub.2, R.sub.3 and R.sub.4 independently of one another are phenyl or biphenyl, which radicals are unsubstituted or substituted; wherein the sum of the Hammett .sigma. constants (.SIGMA..sub..sigma.) of the substitutents on the aromatic radicals R.sub.2, R.sub.3 and R.sub.4 is between +0.36 and +2.58; R.sub.8, R.sub.9, R.sub.14, R.sub.15 and R.sub.16 are, for example, C.sub.1 -C.sub.12 alkyl, phenyl-C.sub.1 -C.sub.6 alkyl or phenyl, and G is a radical which is able to form positive ions. These compounds are suitable as photoinitiators for photopolymerizable compositions which contain acid groups, in the presence of a coinitiator if desired.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: January 4, 2000
    Inventors: Allan Francis Cunningham, Martin Kunz, Hisatoshi Kura
  • Patent number: 6002044
    Abstract: A method for producing a borate compound represented by formula (1) is disclosed, comprising a first step of reacting lithium or magnesium or a compound containing lithium or magnesium, a halide represented by formula (2) and a compound represented by formula (3) in a solvent to produce a boronate compound precursor, a second step of reacting lithium or magnesium or a compound containing lithium or magnesium, a halide represented by formula (4) and the boronate compound precursor obtained in the first step in a solvent to produce a borate metal salt, and a third step of adding an onium halide represented by formula (5) to the borate metal salt obtained in the second step to effect ion-exchange reaction (the formulae are as described in the specification).
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: December 14, 1999
    Assignee: Showa Denko K.K.
    Inventors: Morihiko Yamada, Tsuyoshi Katoh, Norihide Arai
  • Patent number: 5935711
    Abstract: A composition comprises organoborane amine complex and aziridine-functional material. The composition can form a part of a polymerization initiator system that also includes a compound that is reactive with the amine portion of the complex. The system can be used to initiate polymerization of acrylic monomer and to form an acrylic adhesive that has exceptionally good adhesion to low surface energy polymers.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: August 10, 1999
    Assignee: 3M Innovative Properties Company
    Inventors: Alphonsus V. Pocius, E. John Deviny
  • Patent number: 5888473
    Abstract: Boron neutron capture therapy can utilize X.sub.y B.sub.20 H.sub.17 L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH.sub.3, and Na.sub.2 B.sub.10 H.sub.9 NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may have embedded within their bilayers carboranes to increase the amount of delivered .sup.10 B and/or to increase the tumor specificity of the liposome.
    Type: Grant
    Filed: August 3, 1995
    Date of Patent: March 30, 1999
    Assignee: The Regents of the University of California
    Inventors: M. Frederick Hawthorne, Debra Arliene Feakes, Kenneth John Shelly
  • Patent number: 5786485
    Abstract: An optically active .beta.-aminoalkoxyborane complex of the formula (I): ##STR1## wherein R.sup.1 is C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.7 -C.sub.11 aralkyl or C.sub.6 -C.sub.10 aryl, R.sup.2 is hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.7 cycloalkyl or C.sub.7 -C.sub.11 aralkyl, or R.sup.1 and R.sup.2 together form (CH.sub.2).sub.n wherein n is 3 or 4, and Ar is naphthyl, anthryl or phenanthryl, which may be substituted by from 1 to 3 substituents selected from the group consisting of halogen, nitro, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.7 cycloalkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.2 -C.sub.6 alkynyl, C.sub.7 -C.sub.11 aralkyl, C.sub.6 -C.sub.10 aryl, C.sub.1 -C.sub.6 alkoxy and styrene polymer substituents.
    Type: Grant
    Filed: April 29, 1997
    Date of Patent: July 28, 1998
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Hiroshi Kashihara, Mikio Suzuki, Yoshio Ohara
  • Patent number: 5714591
    Abstract: The present invention provides a gadolinium-DTPA complex containing a carborane unit having structural formula (1) given below and an intermediate thereof, i.e., carborane-containing DTPA derivative represented by formula (2) given below. ##STR1## The present invention also provides a method of synthesizing the compound (1), which comprises reacting an ester derivative of DTPA with a carborane derivative in the presence of a palladium catalyst, deesterifying by treatment with an acid, reacting with gadolinium trichloride hexahydrate, and treating with an alkali to give the desired compound (1).
    Type: Grant
    Filed: July 16, 1996
    Date of Patent: February 3, 1998
    Assignee: President of Tohoku University
    Inventors: Yoshinori Yamamoto, Hisao Nemoto
  • Patent number: 5698538
    Abstract: Novel boronic acid and ester and carboxyl-modified amino acid compounds of the Formula I, which are inhibitors of trypsin-like enzymes, are disclosed :R.sup.1 --Z--CHR.sup.2 --A,where R.sup.1, Z, R.sup.2 arid A are defined within.
    Type: Grant
    Filed: July 26, 1996
    Date of Patent: December 16, 1997
    Assignee: The DuPont Merck Pharmaceutical Company
    Inventors: Eugene Cruz Amparo, William Henry Miller, Gregory James Pacofsky, John Wityak, Patricia Carol Weber, John Jonas Vytautas Duncia, Joseph Basil Santella, III
  • Patent number: 5648532
    Abstract: Boron neutron capture therapy can utilize X.sub.y B.sub.20 H.sub.17 L where X is an alkali metal, y is 1 to 4, and L is a two electron donor such as NH.sub.3, and Na.sub.2 B.sub.10 H.sub.9 NCO, among others. These borane salts may be used free or encapsulated in liposomes. Liposomes may have embedded within their bilayers carboranes to increase the amount of delivered .sup.10 B and/or to increase the tumor specificity of the liposome.
    Type: Grant
    Filed: June 3, 1993
    Date of Patent: July 15, 1997
    Assignee: The Regents of the University of California
    Inventors: M. Frederick Hawthorne, Debra Arliene Feakes, Kenneth John Shelly
  • Patent number: 5621143
    Abstract: A complex comprises organoborane and polyoxyalkylenepolyamine. The complexes are useful in systems for initiating the polymerization of acrylic monomer, which systems further include an amine reactive compound. Polymerizable acrylic monomer compositions useful as adhesives can be prepared.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: April 15, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Alphonsus V. Pocius
  • Patent number: 5612295
    Abstract: Multifunctional additives having a variety of advantageous properties are described. They are formed by a process which comprises heating concurrently or in any sequence a) an oil-soluble ashless dispersant containing basic nitrogen with b) an alkoxylated alcohol of at least 8 carbon atoms c) a borating agent and optionally d) an inorganic oxyacid or anhydride of phosphorous. The reactants are in proportions on an active ingredient basis of about 0.03 to about 0.35 part by weight of b) per part by weight of a), and about 0.005 to about 0.06 part by weight of boron as c) per part by weight of a). The reaction temperature can range from about 50.degree. to about 150.degree. C. Water and/or solids present in the resultant mixture can be removed. Preferably, the optional phosphorous component is used in the formation of these additives. This phosphorous component can be an inorganic oxyacid or anhydride of phosphorous.
    Type: Grant
    Filed: March 27, 1996
    Date of Patent: March 18, 1997
    Assignee: Ethyl Corporation
    Inventors: Donald R. Bell, Rolfe J. Hartley, Andrew G. Papay
  • Patent number: 5580984
    Abstract: A retroviral protease inhibiting compound of the formula: ##STR1## is disclosed.
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: December 3, 1996
    Assignee: Abbott Laboratories
    Inventors: Dale J. Kempf, Daniel W. Norbeck, Hing L. Sham, Chen Zhao, Thomas J. Sowin, Daniel S. Reno, Anthony R. Haight
  • Patent number: RE36115
    Abstract: A method for producing amine-boranes, specifically pyridine-borane which is highly stable and of good color is described.
    Type: Grant
    Filed: February 14, 1997
    Date of Patent: February 23, 1999
    Assignee: Boulder Scientific Company
    Inventor: Jeffrey M. Sullivan