Polyoxy Patents (Class 568/633)
  • Patent number: 4156694
    Abstract: The present invention relates to novel benzo(b) bicyclo[3.3.1]nones of the general formula I: ##STR1## and a salt or nitrogen oxide thereof, in which R.sub.1 and R.sub.2 stand for hydrogen, alkyl of 1-6 carbon atoms, alkenyl of 1-6 carbon atoms, an optionally substituted aralkyl group or an acyl group orR.sub.1 and R.sub.2 together with the nitrogen atom represent a heterocyclic 5- or 6-membered ringR.sub.3 is a free, etherified or esterified hydroxy,X and Y stand for hydrogen, hydroxy, halogen, alkyl or alkoxy of 1-6 C-atoms, nitro, CF.sub.3 or an acyloxy group, having valuable biological activities, particularly anorectic activity.
    Type: Grant
    Filed: December 30, 1977
    Date of Patent: May 29, 1979
    Assignee: Akzona Incorporated
    Inventors: Colin L. Hewett, David S. Savage, James Redpath, Thomas Sleigh, Duncan R. Rae
  • Patent number: 4152356
    Abstract: This invention relates to a method of producing a dibenzocycloheptene compound of the structure ##STR1## in high yields which comprises: (a) hydrogenating an anthracene derivative in the 9,10 position to form a 9,10-dihydroanthracene derivative, (b) selectively mono-carbonylating one of the hydrogens in the 9,10 position to form a monoaldehyde, (c) reducing the aldehyde to form the corresponding alcohol and (d) dehydrating and expanding the center ring to form the dibenzocycloheptene compound.
    Type: Grant
    Filed: April 24, 1978
    Date of Patent: May 1, 1979
    Assignee: Exxon Research & Engineering Co.
    Inventor: Chang J. Kim
  • Patent number: 4147806
    Abstract: The active constituents of these medicaments are compounds of the general formula: ##STR1## in which R represents a sulfur or oxygen atom or a >SO or >SO.sub.2 radical or even a ##STR2## IN WHICH R.sub.1 and R.sub.2 which can be the same or different, represent a hydrogen atom or a hydroxyl, aryl, alkyl, arylalkyl, alkylaryl possibly halogenated or a heterocyclic radical, said radicals being substituted or unsubstituted, while R' and R", which may be the same or different, represent a hydrogen atom, a metal such as an alkali or alkaline-earth metal or magnesium, or the ammonium ion or an alkyl radical, an aliphatic or aromatic acyl radical or a heterocyclic radical, which radicals may be substituted or unsubstituted. The process enables the products to be prepared in sufficiently pure form for therapeutic use. .beta.-naphthol is reacted with a suitable aldehyde in an acetic medium, in the presence of hydrochloric acid added dropwise at between 5.degree. and 10.degree. C.
    Type: Grant
    Filed: November 24, 1975
    Date of Patent: April 3, 1979
    Assignee: Laboratoires Creat
    Inventor: Jean-Pierre Poupelin
  • Patent number: 4140724
    Abstract: Disclosed herein is an improved process for preparing an addition product of the reaction of a polyhydric compound and dicyclopentadiene, using a molar ratio of polyhydric compound to dicyclopentadiene of from about 1:4 to about 2:1, in the presence of an acid catalyst wherein the product comprises a hydroxyhydrocarbyl dihydrodicyclopentadiene represented by the formula ##STR1## and wherein R is a divalent radical of 2 to 20 carbon atoms selected from the group consisting of saturated radicals, aromatic radicals and combinations thereof, the improvement comprising employing as the acid catalyst a crosslinked cation exchange resin having acid functionality.
    Type: Grant
    Filed: August 11, 1977
    Date of Patent: February 20, 1979
    Assignee: Rohm and Haas Company
    Inventors: Kayson Nyi, Alan W. Kohr
  • Patent number: 4139544
    Abstract: Carbon-carbon coupled self-condensation products obtained by the oxidative coupling of phenols and naphthols are prepared by contacting an aqueous mixture of phenol or naphthol with oxygen in the presence of sufficient alkaline material to sustain a pH in the range of 8.5-9.5 during the oxidative coupling reaction and a catalyst system comprising a copper, cobalt, nickel, iron, chromium, cerium, or manganese chelate of a polyimino acid containing more than two nitrogen atoms.
    Type: Grant
    Filed: November 26, 1976
    Date of Patent: February 13, 1979
    Assignee: ICI Americas Inc.
    Inventor: Thomas F. Rutledge