Polyoxy Patents (Class 568/660)
  • Publication number: 20150141615
    Abstract: The invention relates to a method or process for the chemical manufacture of depsipeptides of the formula I employing an aldehyde acetal intermediate, wherein the symbols have the meaning defined in the description, to new intermediates and their manufacture, as well as related invention embodiments.
    Type: Application
    Filed: January 14, 2015
    Publication date: May 21, 2015
    Applicant: NOVARTIS AG
    Inventors: Murat ACEMOGLU, Heribert HELLSTERN, Bernard RISS, Christian SPRECHER
  • Publication number: 20150126779
    Abstract: This invention selectively synthesizes a cycloparaphenylene compound having 10, 11, or 13 benzene rings. The invention also synthesizes a cycloparaphenylene compound in which a functional group is introduced into a desired portion. By reacting specific raw materials using a specific reaction, a cyclic compound having 10, 11, or 13 bivalent aromatic hydrocarbon groups, bivalent heterocyclic groups, or derivative groups thereof can be selectively obtained as a pure substance.
    Type: Application
    Filed: March 7, 2013
    Publication date: May 7, 2015
    Inventors: Kenichiro Itami, Yasutomo Segawa, Haruka Omachi, Sanae Matsuura, Yusuke Nakanishi, Yuuki Ishii
  • Publication number: 20150098903
    Abstract: One aspect of the present invention relates to compounds, compositions and methods for diagnosis and/or treatment of a subject suffering from an amyloidosis-associated pathological condition. In certain embodiments, the imaging and/or therapeutic agents of the instant invention may be administered to a subject for identification and/or treatment of amyloid deposits. A specific imaging method detects amyloid deposits by administering the imaging agent to the subject and detecting the spatial distribution of the agent. Differential accumulation of the agent is indicative of AD or an amyloidosis-associated pathological condition and can be monitored by using a PET or SPECT camera.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: David R. Elmaleh, Timothy M. Shoup, Hongning Fu
  • Publication number: 20140363389
    Abstract: Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor is represented by general formula (1) (excluding clotrimazole) and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent.
    Type: Application
    Filed: August 19, 2014
    Publication date: December 11, 2014
    Inventors: Kouji Yokoyama, Makoto Kimura, Masashi Tamai, Yuko Saitoh, Tomomi Kato, Yu Ikeda
  • Patent number: 8889816
    Abstract: Disclosed is a method for preparing a phosphorus-containing polyphenylene oxide resin with a low molecular weight, comprising the steps of: step 1: providing a phosphorus-containing phenolic compound and a raw polyphenylene oxide resin having a number-average molecular weight of more than 10000; step 2: dissolving the raw polyphenylene oxide resin into a solvent to make a solution of the raw polyphenylene oxide resin; step 3: adding the phosphorus-containing phenolic compound into the solution of the raw polyphenylene oxide resin; step 4: introducing an initiator, and carrying out a re-dispersing reaction at a reaction temperature of above 60° C. under the effect of the initiator; and step 5: after the reaction is finished, the product obtained being phosphorus-containing polyphenylene oxide resin with a low molecular weight, the number-average molecular weight thereof being 1000-6000.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: November 18, 2014
    Assignee: Shengyi Technology Co., Ltd.
    Inventors: Yundong Meng, Kehong Fang
  • Patent number: 8841059
    Abstract: A negative resist composition, which shows excellent sensitivity and resolution in pattern formation by exposure to electron beams or EUV, a novel crosslinking agent suitable for the resist composition, and a pattern forming method using the resist composition are presented. The negative resist composition comprises: (A) a polyphenol compound comprising two or more phenolic hydroxyl groups in a molecule thereof and having a molecular weight of 300 to 3,000, (B) an acid generator which directly or indirectly produces acid by exposure to active energy rays having a wavelength of 248 nm or less, and (C) a crosslinking agent represented by the chemical formula (1).
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: September 23, 2014
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Kenichi Okuyama, Yasunori Nagatsuka
  • Patent number: 8816129
    Abstract: The present invention relates to chemical total synthesis methods of six novel protein tyrosine phosphatase-1B (PTP1B) inhibitors and application of the inhibitors in the preparation of medicaments for treating type 2 diabetes mellitus (T2DM). The PTP1B inhibitors use one or more of the six compounds represented by the structural formulae 1, 2, 3, 4, 5 and 6, as active components. The compounds can enhance the sensitivity of an insulin receptor by inhibiting the activity of PTP1B, thereby having a favorable therapeutic effect on insulin-resistant T2DM.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: August 26, 2014
    Assignee: Institute of Oceanology, Chinese Academy of Sciences
    Inventors: Dayong Shi, Shuju Guo, Xiao Fan, Weishen Lu, Yongchao Cui
  • Publication number: 20140199750
    Abstract: The monofunctional branched poly(ethylene glycol) (PEG) has a general formula shown in formula (1), and the bio-related substance modified by the monofunctional branched PEG has a general fomula shown in formula (2), wherein X1 and X2 are each independently a hydrocarbon group having 1 to 20 carbon atoms, n1 and n2 are each independently an integer selected from 1 to 1000, n3 is an integer selected from 11 to 1000, L1, L2 are each independently a linking group, p is 0 or 1, q is 0 or 1, R1 is a hydrogen atom or a hydrocarbon group having 1 to 20 carbon atoms, D is a bio-related substance, Z is a linking group, and Z can react with the bio-related substance to form a residue group L3. The PEG-modified bio-related substance maintains good biological activity, and has better solubility and a longer half-life in vivo.
    Type: Application
    Filed: December 21, 2013
    Publication date: July 17, 2014
    Applicant: Xiamen Sinopeg Biotech, Ltd.
    Inventors: WenGui WENG, Chao LIU, JinCheng LIAO, JinChun YUAN
  • Patent number: 8716532
    Abstract: The present invention provides a method for the preparation of some novel multiconjugated 2- or 4-hydroxy substituted stilbenes. The method provides one pot multicomponent approach wherein 3-4 step reaction sequences viz. condensation, decarboxylation and Heck coupling occur simultaneously which results in an enhanced yield of desired products and reduced reaction times.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: May 6, 2014
    Assignee: Council of Scientific and Industrial Research
    Inventors: Abhishek Sharma, Arun Kumar Sinha, Rakesh Kumar, Naina Sharma
  • Publication number: 20140107348
    Abstract: The present invention relates to methods of initiating a reaction represented by scheme 1 wherein Q is optionally substituted aryl or optionally substituted heteroaryl; X is halogen or a sulphonate; P is an organic radical; R is hydrogen or an organic radical; wherein the catalyst comprises copper and a ligand; comprising providing the compound of formula III in liquid form prior to contacting the compound of formula III with the catalyst.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Applicant: SYNGENTA LIMITED
    Inventors: George Robert HODGES, Lisa MITCHELL, Alan James ROBINSON
  • Patent number: 8629304
    Abstract: The present invention relates to 3-tert-butylbenzaldehyde dimethyl acetal and to 3-tert-butylbenzyl methyl ether and to an electrochemical method for producing 3-tert-butyl-benzaldehyde dimethyl acetal and intermediates passed through in said method.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: January 14, 2014
    Assignee: BASF SE
    Inventors: Florian Stecker, Andreas Fischer, Jörg Botzem, Ulrich Griesbach, Ralf Pelzer
  • Publication number: 20140008571
    Abstract: The invention relates to a liquid-crystalline medium which comprises at least one compound of the formula I, in which R1, R1*, L1, L2 and L3 have the meanings indicated in Claim 1, and to the use thereof for an active-matrix display, in particular based on the VA, PSA, PS-VA, PA-VA, PALC, FFS, PS-FFS, IPS or PS-IPS effect. The invention furthermore also relates to compounds of the formula I.
    Type: Application
    Filed: February 27, 2012
    Publication date: January 9, 2014
    Applicant: MERCK PATENT GMBH
    Inventors: Melanie Klasen-Memmer, Matthias Bremer, Harald Lannert, Konstantin Schneider
  • Publication number: 20130324768
    Abstract: The present invention produces Cyclic Compound (1) in which organic ring groups including cyclohexane rings and benzene rings are continuously bonded, using a compound having at least one cyclohexane ring and benzene rings with halogen atoms at the two terminuses, in the presence of a nickel compound (bis(1,5-cyclooctadiene)nickel, etc.). Thereafter, by converting the cyclohexane rings in Cyclic Compound (1) into benzene rings, a desired carbon nanoring can be obtained. Thereby, the present invention efficiently produces a carbon nanoring made of a compound having a cyclic structure in which a desired number of organic ring groups are continuously bonded, with a short production process.
    Type: Application
    Filed: March 8, 2011
    Publication date: December 5, 2013
    Applicant: National University Corporation Nagoya University
    Inventors: Kenichiro Itami, Yasutomo Segawa, Shinpei Miyamoto, Haruka Omachi, Sanae Matsuura, Petr Senel
  • Publication number: 20130323640
    Abstract: Embodiments in accordance with the present invention provide for norbornane-type ballast materials, norbornane-type photoactive compounds derived from such ballast materials and alkali-soluble positive-tone polymer compositions that encompass such norbornane-type photoactive compounds and one of a PBO or PNB resin.
    Type: Application
    Filed: August 9, 2013
    Publication date: December 5, 2013
    Applicants: Sumitomo Bakelite Co., Ltd., Promerus, LLC
    Inventors: Andrew Bell, Keitaro Seto, Hiroaki Makabe
  • Publication number: 20130302990
    Abstract: The invention provides an organic film composition comprises (A) a heat-decomposable polymer, (B) an organic solvent, and (C) an aromatic ring containing resin, with the weight reduction rate of (A) the heat-decomposable polymer from 30° C. to 250° C. being 40% or more by mass. There can be provided an organic film composition having not only a high dry etching resistance but also an excellent filling-up or flattening characteristics.
    Type: Application
    Filed: April 30, 2013
    Publication date: November 14, 2013
    Applicant: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Takeru WATANABE, Seiichiro TACHIBANA, Toshihiko FUJII, Kazumi NODA, Toshiharu YANO, Takeshi KINSHO
  • Publication number: 20130267474
    Abstract: The present invention describes phytochemicals present in maple syrup and maple tree extracts by butanol, ethyl acetate and methanol. Novel compounds are isolated from maple syrups, including one compound Quebecol generated in the maple syrup manufacturing process. Also described are digesting extract of maple syrup. The phytochemicals may be used for the treatment or prevention of cancers, metabolic syndromes, diabetes, microorganism infections and/or antioxidants.
    Type: Application
    Filed: August 19, 2011
    Publication date: October 10, 2013
    Applicants: UNIVERSITY OF RHODE ISLAND, FÉDÉRATION DES PRODUCTEURS ACÉRICOLES DU QUÉBEC
    Inventors: Navindra P. Seeram, Liya Li, Geneviéve Béland, Julie Barbeau
  • Publication number: 20130183460
    Abstract: The invention relates to liquid-crystalline media which can be used, in particular, for electro-optical displays having active-matrix addressing based on the ECB effect and for IPS (in-plane switching) displays or FFS (fringe field switching) displays.
    Type: Application
    Filed: December 20, 2012
    Publication date: July 18, 2013
    Applicant: MERCK PATENT GMBH
    Inventor: MERCK PATENT GMBH
  • Publication number: 20130131182
    Abstract: The present invention relates to chemical total synthesis methods of six novel protein tyrosine phosphatase-1B (PTP1B) inhibitors and application of the inhibitors in the preparation of medicaments for treating type 2 diabetes mellitus (T2DM). The PTP1B inhibitors use one or more of the six compounds represented by the structural formulae 1, 2, 3, 4, 5 and 6, as active components. The compounds can enhance the sensitivity of an insulin receptor by inhibiting the activity of PTP1B, thereby having a favorable therapeutic effect on insulin-resistant T2DM.
    Type: Application
    Filed: July 7, 2011
    Publication date: May 23, 2013
    Applicant: INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Dayong Shi, Shuju Guo, Xiao Fan, Weishen Lu, Yongchao Cui
  • Publication number: 20130017163
    Abstract: The present invention provides compositions and methods of their administration for the protection of cells and tissues from damage caused by FROS in the body of an individual. Compositions comprising halogenated phenol compounds are provided that scavenge or consume FROS in the body. These FROS scavenging compounds may not only protect cells and tissues from damage, but also treat disease and/or alleviate the symptoms of disease associated with high FROS levels. Sunscreen compositions comprising FROS-scavenging compounds of the present invention are further provided to reduce the damaging effects of sunlight on the skin of an individual.
    Type: Application
    Filed: July 13, 2012
    Publication date: January 17, 2013
    Inventor: Keith R. Latham
  • Publication number: 20120252997
    Abstract: Fluorinated arylene-containing compounds and fluorinated polymers formed from fluorinated arylene-containing compounds, and methods are described. Fluorinated polymers formed from fluorinated arylene-containing compound can be used to provide a low energy surface.
    Type: Application
    Filed: December 17, 2010
    Publication date: October 4, 2012
    Inventors: Yu Yang, George G.I. Moore, John C. Clark
  • Publication number: 20120251492
    Abstract: Provided are a triterpene derivative represented by a general formula (I), a pharmaceutically acceptable salt thereof, and an agent for preventing or treating chronic hepatitis C comprising the triterpene derivative or the salt as an active ingredient: [in the formula (I), R1 represents a carboxyl group, a hydroxymethyl group, —CH2OSO3H, or and R2 represents —OR3 or —O— (CH2) m-OR4, where R3 represents a benzyl group which may be substituted with a hydroxymethyl group, a dimethylaminomethyl group, a phenylaminomethyl group, a morpholinomethyl group, a carboxyl group, or a formyl group, a C1-6 alkyl group, a C2-6 alkenyl group, a C2-6 alkynyl group, or a hydroxy C1-6 alkyl group, R4 represents a phenyl group which may be substituted with a carboxyl group, and m represents an integer of 1 to 3, with the proviso that a case where R1 is —CH2OH, and R3 is a C1-6 alkyl group, a C2-6 alkenyl group, or a benzyl group is excluded].
    Type: Application
    Filed: December 15, 2010
    Publication date: October 4, 2012
    Applicant: MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Makoto Ishikawa, Shigeki Suzuki, Makoto Aoki, Nobuto Minowa, Kokichi Suzuki
  • Patent number: 8227645
    Abstract: The present invention relates to a cyclization process of forming a multiple ring compound from an isoprenoid compound. The cyclization process involves reacting the isoprenoid compound with an acetal initiator under conditions sufficient to form the multiple ring compound. The isoprenoid compound is contacted with an initiator an optionally with a catalyst. Cyclization occurs by reaction of the initiator with the isoprenoid compound. Cyclic acetal compounds wherein the acetal forms part of 6-membered unsaturated ring are also defined.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: July 24, 2012
    Assignee: Nanyang Technological University
    Inventors: Teck Peng Loh, Yu Jun Zhao
  • Publication number: 20120165528
    Abstract: The present invention relates to chiral binaphthyl compounds having good solubility and high helical twisting power. The chiral binaphthyl compounds as dopants in the liquid crystal compositions can help enhance the display quality of the liquid crystal panels.
    Type: Application
    Filed: April 27, 2011
    Publication date: June 28, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Jian-Wen Lin, Chun-Ming Wu, Shih-Hsien Liu, Kung-Lung Cheng
  • Publication number: 20120135352
    Abstract: Embodiments in accordance with the present invention provide for norbornane-type ballast materials, norbornane-type photoactive compounds derived from such ballast materials and alkali-soluble positive-tone polymer compositions that encompass such norbornane-type photoactive compounds and one of a PBO or PNB resin.
    Type: Application
    Filed: September 28, 2011
    Publication date: May 31, 2012
    Applicant: Promerus LLC
    Inventors: Andrew Bell, Keitaro Seto, Hiroaki Makabe, Edmund Elce
  • Patent number: 8148551
    Abstract: The invention relates to tricyclic aromatics of the general formula I in which A1, A2, A3, A4, Q1-Q2, R1, R2, X1, X2, X3, Z1, Z2, Z3, Z4, q, r, s, t and u have the meaning indicated, and to the use thereof as components of liquid-crystalline media and to an electro-optical display element containing same.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: April 3, 2012
    Assignee: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Rudolf Eidenschink, Holger Kretzschmann
  • Publication number: 20120016162
    Abstract: The present invention relates to 3-tert-butylbenzaldehyde dimethyl acetal and to 3-tert-butylbenzyl methyl ether and to an electrochemical method for producing 3-tert-butyl-benzaldehyde dimethyl acetal and intermediates passed through in said method.
    Type: Application
    Filed: March 27, 2009
    Publication date: January 19, 2012
    Applicant: BASF SE
    Inventors: Florian Stecker, Andreas Fischer, Jörg Botzem, Ulrich Griesbach, Ralf Pelzer
  • Publication number: 20110256549
    Abstract: Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.
    Type: Application
    Filed: March 17, 2011
    Publication date: October 20, 2011
    Applicant: Sirigen, Inc.
    Inventors: Brent S. Gaylord, Jean M. Wheeler, Glenn P. Bartholomew, Frank Peter Uckert, Janice W. Hong, William H. Huisman
  • Publication number: 20110243865
    Abstract: Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor comprises a compound represented by general formula (1) (excluding clotrimazole), and/or a pharmacologically acceptable salt thereof.
    Type: Application
    Filed: December 22, 2009
    Publication date: October 6, 2011
    Applicant: POLA CHEMICAL INDUSTRIES INC.
    Inventors: Kouji Yokoyama, Makoto Kimura, Masashi Tamai, Yuko Saitoh, Tomomi Kato, Yu Ikeda
  • Publication number: 20110220883
    Abstract: A compound for an organic thin film transistor having a structure of the following formula (1): wherein R1 to R6 are independently a hydrogen atom, a halogen atom, an alkyl group having 1 to 30 carbon atoms, a haloalkyl group having 1 to 30 carbon atoms, an alkoxy group having 1 to 30 carbon atoms, a haloalkoxy group having 1 to 30 carbon atoms, an alkylthio group having 1 to 30 carbon atoms, a haloalkylthio group having 1 to 30 carbon atoms, an alkylamino group having 1 to 30 carbon atoms, a dialkylamino group having 2 to 60 carbon atoms (the alkyl groups may be combined with each other to form a ring structure containing the nitrogen atom), an alkylsulfonyl group having 1 to 30 carbon atoms, a haloalkylsulfonyl group having 1 to 30 carbon atoms, an aromatic hydrocarbon group having 6 to 60 carbon atoms, an aromatic heterocyclic group having 3 to 60 carbon atoms, an alkylsilyl group having 3 to 20 carbon atoms, an alkylsilylacetylene group having 5 to 60 carbon atoms or a cyano group, which each may have
    Type: Application
    Filed: August 5, 2009
    Publication date: September 15, 2011
    Applicant: IDEMITSU KOSAN CO., LTD.
    Inventors: Yuki Nakano, Masatoshi Saito, Hiroaki Nakamura
  • Publication number: 20110178323
    Abstract: Provided is a method for producing a tetrafluoro nitrogen-containing heterocyclic compound such as tetrafluoropyrrolidine in good yield and at low cost. The method comprises the steps of: (A) reacting a compound represented by the formula (I) with fluorine gas to produce a tetrafluoro compound represented by the formula (II), (B) converting the tetrafluoro derivative represented by the formula (II) to a compound represented by the formula (III), and (C) reacting the compound represented by the formula (III) with an amine compound represented by the formula NH2R9 to produce a tetrafluoro nitrogen-containing heterocyclic compound represented by the formula (IV) or salt thereof.
    Type: Application
    Filed: October 2, 2009
    Publication date: July 21, 2011
    Applicant: NIPPON SODA CO., LTD.
    Inventor: Yasuhiro Miyashita
  • Publication number: 20110160228
    Abstract: The present invention relates to compounds of formula (I) below in which: —R1 and R3 represent, independently of one another, a methoxy group optionally substituted by one or more fluorine atoms, —R2 and R4 represent, independently of one another, a hydrogen atom or a methoxy group optionally substituted by one or more fluorine atoms, —A represents a ring chosen from the group comprising aryl and heteroaryl groups, said ring possibly being substituted by or fused to a heterocycle, —X represents a nitrogen atom or a CH group, and —Z1 represents a hydrogen atom or a halogen atom, preferably fluorine, and —Z2 represents a hydrogen atom, a halogen atom, preferably fluorine, a C1 to C4 alkyl group, an aryl group or a —CN, —SO2NR12R13, —SO2R9, —COOR15 or —COR15 group, and also to the pharmaceutically acceptable salts thereof, the isomers thereof and the prodrugs thereof.
    Type: Application
    Filed: June 4, 2009
    Publication date: June 30, 2011
    Inventors: Mouâd Alami, Samir Messaoudi, Abdallah Hamze, Olivier Provot, Jean-Daniel Brion, Jian-Miao Liu, Jérôme Bignon, Joanna Bakala
  • Patent number: 7939185
    Abstract: A fused polycyclic compounds is represented by the general formula (I): wherein X1 to X18 each represent, independently of one another, a hydrogen atom, a halogen atom, a cyano group, a nitro group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, a substituted or unsubstituted aralkyl group, a substituted amino group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heterocyclic group.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: May 10, 2011
    Assignee: Canon Kabushiki Kaisha
    Inventors: Naoki Yamada, Minako Nakasu, Satoshi Igawa, Masashi Hashimoto
  • Patent number: 7884133
    Abstract: Cannabinoid derivatives are known for their function in the central as well as peripheral nervous system. Disclosed are some novel (+)-cannabidiol (CBD) derivatives of the general formula (I) having selective activity in the peripheral, but not in the central nervous system. Use of (+)-CBD derivatives as analgesics, anti-inflammatory and anti-diarrheal agents is also disclosed.
    Type: Grant
    Filed: September 8, 2004
    Date of Patent: February 8, 2011
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem, Ariel Ltd.
    Inventors: Raphael Mechoulam, Ester Fride
  • Publication number: 20110017985
    Abstract: The present invention is an electronic device and a process for making the electronic device in which the semiconductor component comprises at least one carbon nanotube functionalized with a fluorinated olefin. Functionalization with the fluorinated olefin renders the carbon nanotube semiconducting.
    Type: Application
    Filed: April 1, 2009
    Publication date: January 27, 2011
    Inventors: Graciela Beatriz Blanchet, Helen S.M. Lu
  • Publication number: 20110003902
    Abstract: There are provided: a proton transporting material that improves mechanical characteristics of a sulfonated liquid crystalline polymer material, can be kept as a membrane even though it is made a solid state while maintaining a molecular arrangement of a liquid crystalline state, and is suitable for electrolyte membranes of fuel cells etc.; an ion exchange membrane, a membrane electrolyte assembly (MEA), and a fuel cell that use the proton transporting material; a starting material for the proton transporting material. The proton transporting material has a molecular structure produced by crosslinking the sulfonated liquid crystalline polymer material with a crosslinking agent having two or more functional groups in sites except that of the sulfonic acid group.
    Type: Application
    Filed: March 3, 2009
    Publication date: January 6, 2011
    Inventors: Yuichiro Haramoto, Kohei Shiramizu, Masashi Oota
  • Publication number: 20100327240
    Abstract: Compounds are disclosed for the production of chemiluminescent light, particularly for the production of blue/violet light within the range of about 390 nm to less than 438 nm, and most particularly to the use of compounds composed of symmetrically and asymmetrically substituted anthracenes which are effective for increasing the production of such blue/violet light when used as fluorescers in conjunction with chemiluminescent systems. These systems utilize derivatives of 9,10-diphenylanthracene containing one or more fluorines As shown in General Formulae 1-3. The variables shown in Formulae 1-3 are defined in the specification.
    Type: Application
    Filed: June 24, 2010
    Publication date: December 30, 2010
    Inventors: Earl Cranor, Linda Jacob
  • Publication number: 20100305364
    Abstract: The present invention relates to a new process for preparing diisopropyl {[1-(hydroxymethyl)-cyclopropyl]oxy}methylphosphonate (2), which is a key intermediate for synthesizing an antiviral (particularly, against hepatitis B virus) nucleoside analogue. The present invention also relates to new intermediates, and a process for preparing the antiviral nucleoside analogue from the compound (2) prepared according to the present invention.
    Type: Application
    Filed: August 10, 2010
    Publication date: December 2, 2010
    Inventors: Suk-Kyoon YOON, Kun-Hye Nam, Sang-Who Lee, Won-Kyo Joung, Sang-Chul Choi, Ki-Kon Lee
  • Patent number: 7838618
    Abstract: A process for producing a phenylene ether oligomer comprising oxidative polymerization of a specific bivalent phenol compound and a specific monovalent phenol compound in an aromatic hydrocarbon solvent, wherein the aromatic hydrocarbon solvent of a phenylene ether oligomer solution obtained after the termination of the polymerization is replaced with a water-soluble organic solvent having a boiling point higher than that of the aromatic hydrocarbon solvent and the resultant phenylene ether oligomer solution is brought into contact with water, thereby precipitating the phenylene ether oligomer as particles.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: November 23, 2010
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Kiyonari Hiramatsu, Yoshio Mukai, Hidemi Hirashima, Yuji Takeda
  • Publication number: 20100291299
    Abstract: Cyclopentadienyl and Indenyl barium/strontium metal precursors and Lewis base adducts thereof are described. Such precursors have utility for forming Ba- and/or Sr-containing films on substrates, in the manufacture of microelectronic devices or structures.
    Type: Application
    Filed: August 3, 2008
    Publication date: November 18, 2010
    Applicant: ADVANCED TECHNOLOGY MATERIALS, INC.
    Inventors: Thomas M. Cameron, Chongying Xu
  • Patent number: 7795463
    Abstract: Disclosed is a process for preparing a compound of the following formula (2): including the steps of reacting a compound of the following formula (4): with trityl chloride to prepare trityloxy-acetic acid ethyl ester of the following formula (8): reacting the compound of formula (8) with ethyl magnesium halide to prepare 1-trityloxymethyl-cyclopropanol of the following formula (9): combining the 1-trityloxymethyl-cyclopropanol of formula (9) with diisopropylbromo-methylphosphonate in a solvent in the presence of a base to prepare (1-trityloxymethyl-cyclopropoxymethyl)-phosphonic acid diisopropyl ester of the following formula (10): as a solid form, and converting the trityl group of the compound of formula (10) into a hydroxyl group.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: September 14, 2010
    Assignee: LG Life Sciences Ltd.
    Inventors: Suk-Kyoon Yoon, Kun-Hye Nam, Sang-Who Lee, Won-Kyo Joung, Sang-Chul Choi, Ki-Kon Lee
  • Publication number: 20100228058
    Abstract: The present invention relates to a cyclisation process of forming a multiple ring compound from an isoprenoid compound. The cyclisation process involves reacting the isoprenoid compound with an acetal initiator under conditions sufficient to form the multiple ring compound. The isoprenoid compound is contacted with an initiator an optionally with a catalyst. Cyclisation occurs by reaction of the initiator with the isoprenoid compound. Cyclic acetal compounds wherein the acetal forms part of 6-membered unsaturated ring are also defined.
    Type: Application
    Filed: February 22, 2007
    Publication date: September 9, 2010
    Applicant: NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Teck Peng Loh, Yu Jun Zhao
  • Patent number: 7754837
    Abstract: Disclosed are telechelic fluoropolymers and methods for forming the polymers. The fluoropolymers can be formed via step-growth polymerization of bis(trifluorovinyloxy)biphenyls with bisphenols. The formed telechelic polymers possess fluoroolefin functionality at the trifluorovinyl aromatic ether endgroups. Internal groups can include difluorodioxyvinylene groups and trifluoroethyl groups. Formation methods of the telechelic polymers can be controlled so as to control molecular weight and degree of unsaturation of the polymers. The end groups and the internal groups can be further reacted independently of each other, e.g., under different temperature conditions, to form a variety of polymers and/or crosslinked polymeric networks.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: July 13, 2010
    Assignee: Clemson University Research Foundation
    Inventors: Dennis W. Smith, Jr., Scott T. Iacono
  • Patent number: 7705190
    Abstract: A method for carrying out a chemical reaction between at least two reactants occupying separate phases within a multiphase reaction mixture has been discovered in which at least one phosphazenium salt is employed as a phase transfer catalyst. The remarkable utility of phosphazenium salts as phase transfer catalysts is illustrated by the preparation of aromatic ethers. The phosphazenium salt phase transfer catalysts are shown to be especially useful in the preparation of aromatic polyethers such as polyether sulfones.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: April 27, 2010
    Assignee: Sabic Innovative Plastics IP B.V.
    Inventor: Daniel Joseph Brunelle
  • Publication number: 20100048731
    Abstract: The present invention relates to a compound of general formula (I) below in which R1, R2 and R3 represent, independently of one another, a hydrogen atom or a C1-C6 alkyl group or a (C1-C6 alkyl)carbonyl group, R4, R5, R6 and R7 represent a hydrogen or a C1-C6 alkyl group, a C1-C6 alkoxy group or a (C1-C6 alkyl)carbonyloxy group, and n is an integer between 8 and 20, or its pharmaceutically acceptable addition salts, isomers, enantiomers and diastereoisomers, and also mixtures thereof. The invention also relates to a pharmaceutical composition comprising the compound and to the use thereof as a neurotrophic agent.
    Type: Application
    Filed: March 2, 2007
    Publication date: February 25, 2010
    Applicants: Centre National de la Recherche Scientifique(CNRS), Universite de Luxembourg
    Inventors: Bang Luu, Frédérique Hauss, Djalil Coowar, Jiawei Liu, Paul Heuschling, Eleonora Morga, Luc Grandbarbe, Alessandro Michelucci
  • Patent number: 7625499
    Abstract: The present invention provides a conductive liquid-crystal material having features including that, for example, excellent conductivity is exhibited at a low threshold voltage of about 5 V even in a room temperature range, the value of resistance varies with an applied voltage, the current density rises sharply at a voltage of about 5 V, and an excellent charge mobility is exhibited, as well as a process for producing the conductive liquid-crystal material, a liquid-crystal composition which is used for the conductive liquid-crystal material, a liquid-crystal semiconductor element, and an information recording medium.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: December 1, 2009
    Assignee: Nippon Chemical Industrial Co., Ltd.
    Inventor: Yuichiro Haramoto
  • Patent number: 7582781
    Abstract: The present invention provides an industrially safe, easily operable process for producing an optically active epoxy alcohol derivative useful as an intermediate for pharmaceuticals from inexpensively available materials, and also provides a novel halohydrin derivative serving as an important intermediate for the epoxy alcohol derivative. Furthermore, the present invention provides a process for producing an intermediate for a triazole antifungal agent by allowing a halohydrin to react with a triazole sulfonamide, the process including a small number of steps.
    Type: Grant
    Filed: July 5, 2004
    Date of Patent: September 1, 2009
    Assignee: Kaneka Corporation
    Inventors: Kazumi Okuro, Tatsuyoshi Tanaka, Masaru Mitsuda, Kenji Inoue
  • Publication number: 20090216043
    Abstract: The invention relates to aromatically substituted glycerine ethers of formula (I), wherein at least one of the radicals R1, R2, or R3 is or contains an aromatic group. Said compounds can be used, preferably, as surface-active agents.
    Type: Application
    Filed: June 22, 2006
    Publication date: August 27, 2009
    Applicant: CLARIANT PRODUKTE (DEUTSCHLAND) GMBH
    Inventors: Joachim Hess, Ralf Zerrer, Franz-Xaver Scherl, Christian Sowa
  • Publication number: 20090215978
    Abstract: A process for the alkoxyalkylation of an unsubstituted aromatic substrate or a substituted aromatic substrate, said substitution being via a carbon-carbon bond, said process comprising reacting the aromatic substrate with a dialkoxyalkane in the presence of a catalyst.
    Type: Application
    Filed: February 21, 2006
    Publication date: August 27, 2009
    Applicant: Davy Process Technology Limited
    Inventors: Simon Darby Roberts, Stephan William Colley
  • Publication number: 20090189518
    Abstract: A fused polycyclic compounds is represented by the general formula (I): wherein X1 to X18 each represent, independently of one another, a hydrogen atom, a halogen atom, a cyano group, a nitro group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkoxy group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted alkynyl group, a substituted or unsubstituted aralkyl group, a substituted amino group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heterocyclic group.
    Type: Application
    Filed: November 21, 2008
    Publication date: July 30, 2009
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Naoki Yamada, Minako Nakasu, Satoshi Igawa, Masashi Hashimoto
  • Patent number: 7550619
    Abstract: Intermediates useful in the preparation of the antiviral agent entecavir are disclosed. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various processes useful in the preparation of entecavir are also disclosed.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: June 23, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yadagiri R. Pendri, Chung-Pin H. Chen, Jing Liang, Shaopeng Wang, Milan Stojanovic, Richard P. Polniaszek, John Thottathil, Dhileepkumar Krishnamurty