Plural Alicyclic Rings Containing Patents (Class 568/664)
  • Publication number: 20150118165
    Abstract: The present invention relates to the use of at least one cyclohexanol ether derivative of the formula I as antimicrobial active compound or as anti-acne, antidandruff, deodorant or antiperspirant active compound, to preparations comprising these compounds, and to specific cyclohexanol ether derivatives.
    Type: Application
    Filed: April 5, 2013
    Publication date: April 30, 2015
    Applicant: Merck Patent GmbH
    Inventors: Thomas Rudolph, Sylvia Eisenberg
  • Publication number: 20150118172
    Abstract: The present invention relates to the use of at least one dicyclohexylmethanol derivative of the formula (I) as antimicrobial active compound or as anti-acne, antidandruff, deodorant or antiperspirant active compound, to preparations comprising these compounds, and to specific dicyclohexylmethanol derivatives and to a process for the preparation thereof.
    Type: Application
    Filed: April 5, 2013
    Publication date: April 30, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Thomas Rudolph, Tatjana Best
  • Patent number: 8999197
    Abstract: The invention provides a liquid crystal compound that has an excellent compatibility with other liquid crystal compounds and also has at least one of characteristics such as a high stability to heat, light or the like, a suitable refractive index anisotropy (?n), a low threshold voltage and a suitable dielectric anisotropy (??). A compound represented by formula (1) For example, R1 is alkyl having 1 to 10 carbons, R2 is halogen or alkenyl having 2 to 10 carbons; the ring A1, the ring A2 and the ring A3 are 1,4-cyclohexylene or 1,4-phenylene; Z1, Z2 and Z3 are a single bond or alkylene having 1 to 4 carbons; G is —CH2— or —O—; and m is 1, and n and p is 0 or 1.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: April 7, 2015
    Assignees: JNC Corporation, JNC Petrochemical Corporation
    Inventors: Tokifumi Masukawa, Yasuyuki Goto, Tomohiro Yano
  • Publication number: 20150069297
    Abstract: A liquid crystal compound having high stability to heat and light, etc., a high clearing point, a low minimum temperature of liquid crystal phase, a low viscosity, a suitable optical anisotropy, a large dielectric anisotropy, a suitable elastic constant, and good compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound, and a LCD element using the composition are described. The compound is represented by formula (1): wherein, for example, R1 is C1-10 alkyl, ring A1, ring A2, ring A3, ring A4 and ring B1 are independently 1,4-cyclohexylene, 1,4-phenylene, 1,4-phenylene in which at least one hydrogen is substituted with halogen, 1,3-dioxane-2,5-diyl, or tetrahydropyran-2,5-diyl, Z1, Z2, Z3 and Z4 are single bonds, l, m, n and o are independently 0 or 1, and l+m+n+o?1.
    Type: Application
    Filed: February 7, 2013
    Publication date: March 12, 2015
    Inventor: Hiroyuki Tanaka
  • Patent number: 8956552
    Abstract: To provide a compound, when the compound has both a high clearing point and a low crystallization temperature, having a wide temperature range of a liquid crystal phase and also an excellent solubility in other liquid crystal compounds, and further having general physical properties necessary for the compound, namely, stability to heat, light and so forth, a suitable optical anisotropy and a suitable dielectric anisotropy. A compound is represented by formula (1): wherein, for example, Ra and Rb are alkyl having 1 to 10 carbons; A1, A2, A3 and A4 are 1,4-phenylene; Z1, Z2, Z3 and Z4 are a single bond or alkylene having 1 to 4 carbons; and m, n, q and r are independently 0, 1, or 2, and a sum of m, n, q and r is 1, 2, 3 or 4.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: February 17, 2015
    Assignees: JNC Corporation, JNC Petrochemical Corporation
    Inventor: Yasuyuki Sasada
  • Patent number: 8858829
    Abstract: The present invention intends to provide a novel cyclohexane compound that can form a liquid crystal composition of which response speed is improved when mixed with a nematic liquid crystal and the like and to provide a specified liquid crystal composition in which a novel cyclohexane compound is mixed. The novel cyclohexane compound is represented by the following formula (1). (In the formula (1), R1 and R2 represent the same or different R, ROCO or RCOO, and the R represents an alkyl group. The alkyl group may have an unsaturated bond, and, in the group, —CH2— may be substituted with —O—, —CO— or —COO—, and a part of or an entirety of hydrogen atoms may be substituted with a halogen atom or a cyano group. X and Y each independently represents a halogen atom or a hydrogen atom and does not simultaneously represent a hydrogen atom. Further, alternatively, X represents an oxygen atom and Y represents a direct bond to the oxygen atom.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: October 14, 2014
    Assignees: Organo Science Co., Ltd., Chiracol Co., Ltd.
    Inventors: Kazuo Okamoto, Toshihiro Shibata
  • Publication number: 20140217325
    Abstract: The present invention relates to liquid-crystalline media and to high-frequency components comprising same, especially microwave components for high-frequency devices, such as devices for shifting the phase of microwaves, in particular for microwave phased-array antennas.
    Type: Application
    Filed: August 7, 2012
    Publication date: August 7, 2014
    Applicant: MERCK PATENT GMBH
    Inventors: Atsutaka Manabe, Dagmar Klass
  • Publication number: 20140054499
    Abstract: The invention provides a liquid crystal compound that has an excellent compatibility with other liquid crystal compounds and also has at least one of characteristics such as a high stability to heat, light or the like, a suitable refractive index anisotropy (?n), a low threshold voltage and a suitable dielectric anisotropy (??). A compound represented by formula (1). For example, R1 is alkyl having 1 to 10 carbons, R2 is halogen or alkenyl having 2 to 10 carbons; the ring A1, the ring A2 and the ring A3 are 1,4-cyclohexylene or 1,4-phenylene; Z1, Z2 and Z3 are a single bond or alkylene having 1 to 4 carbons; G is —CH2— or —O—; and m is 1, and n and p is 0 or 1.
    Type: Application
    Filed: October 24, 2013
    Publication date: February 27, 2014
    Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATION
    Inventors: Tokifumi MASUKAWA, Yasuyuki GOTO, Tomohiro YANO
  • Publication number: 20130302990
    Abstract: The invention provides an organic film composition comprises (A) a heat-decomposable polymer, (B) an organic solvent, and (C) an aromatic ring containing resin, with the weight reduction rate of (A) the heat-decomposable polymer from 30° C. to 250° C. being 40% or more by mass. There can be provided an organic film composition having not only a high dry etching resistance but also an excellent filling-up or flattening characteristics.
    Type: Application
    Filed: April 30, 2013
    Publication date: November 14, 2013
    Applicant: SHIN-ETSU CHEMICAL CO., LTD.
    Inventors: Takeru WATANABE, Seiichiro TACHIBANA, Toshihiko FUJII, Kazumi NODA, Toshiharu YANO, Takeshi KINSHO
  • Publication number: 20130277612
    Abstract: To provide a compound, when the compound has both a high clearing point and a low crystallization temperature, having a wide temperature range of a liquid crystal phase and also an excellent solubility in other liquid crystal compounds, and further having general physical properties necessary for the compound, namely, stability to heat, light and so forth, a suitable optical anisotropy and a suitable dielectric anisotropy. A compound is represented by formula (1): wherein, for example, Ra and Rb are alkyl having 1 to 10 carbons; A1, A2, A3 and A4 are 1,4-phenylene; Z1, Z2, Z3 and Z4 are a single bond or alkylene having 1 to 4 carbons; and m, n, q and r are independently 0, 1, or 2, and a sum of m, n, q and r is 1, 2, 3 or 4.
    Type: Application
    Filed: June 17, 2013
    Publication date: October 24, 2013
    Applicants: JNC CORPORATION
    Inventor: Yasuyuki SASADA
  • Publication number: 20130271719
    Abstract: To provide a liquid crystal compound having a large positive value of dielectric anisotropy and a small viscosity. The compound is represented by formula (1): wherein, in formula (1), R1 is alkyl having 1 to 20 carbons or the like; ring A1 is 1,4-cyclohexylene or the like; ring A2 is 1,4-phenylene, 2-fluoro-1,4-phenylene, 2,6-difluoro-1,4-phenylene or the like; ring A3 is 1,4-cyclohexylene, 1,4-phenylene, 2-fluoro-1,4-phenylene, 2,6-difluoro-1,4-phenylene or the like; and X1 is halogen, alkyl having 1 to 10 carbons or the like, and in the alkyl, at least one of hydrogen may be replaced by halogen.
    Type: Application
    Filed: April 4, 2013
    Publication date: October 17, 2013
    Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATION
    Inventors: Takahiro KUBO, Yasuyuki GOTOH
  • Publication number: 20130270480
    Abstract: To provide a compound, when the compound has both a high clearing point and a low crystallization temperature, having a wide temperature range of a liquid crystal phase and also an excellent solubility in other liquid crystal compounds, and further having general physical properties necessary for the compound, namely, stability to heat, light and so forth, a suitable optical anisotropy and a suitable dielectric anisotropy. A compound is represented by formula (1): wherein, for example, Ra and Rb are alkyl having 1 to 10 carbons; A1, A2, A3 and A4 are 1,4-phenylene; Z1, Z2, Z3 and Z4 are a single bond or alkylene having 1 to 4 carbons; and m, n, q and r are independently 0, 1, or 2, and a sum of m, n, q and r is 1, 2, 3 or 4.
    Type: Application
    Filed: October 13, 2011
    Publication date: October 17, 2013
    Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATION
    Inventor: Yasuyuki Sasada
  • Publication number: 20130092875
    Abstract: The present invention intends to provide a novel cyclohexane compound that can form a liquid crystal composition of which response speed is improved when mixed with a nematic liquid crystal and the like and to provide a specified liquid crystal composition in which a novel cyclohexane compound is mixed. The novel cyclohexane compound is represented by the following formula (1). (In the formula (1), R1 and R2 represent the same or different R, ROCO or RCOO, and the R represents an alkyl group. The alkyl group may have an unsaturated bond, and, in the group, —CH2— may be substituted with —O—, —CO— or —COO—, and a part of or an entirety of hydrogen atoms may be substituted with a halogen atom or a cyano group. X and Y each independently represents a halogen atom or a hydrogen atom and does not simultaneously represent a hydrogen atom. Further, alternatively, X represents an oxygen atom and Y represents a direct bond to the oxygen atom.
    Type: Application
    Filed: June 30, 2011
    Publication date: April 18, 2013
    Applicants: Chiracol Co., Ltd., Organo Science Co., Ltd.
    Inventors: Kazuo Okamoto, Toshihiro Shibata
  • Patent number: 8410234
    Abstract: A vinyl ether compound represented by formula (1-a) or formula (1-b): wherein n represents 0 or 1, and R1 and R2 each independently represent a hydrogen atom, a methyl group, or an ethyl group, provided that a total of the number of carbon atoms of R1 and the number of carbon atoms of R2 is 1 or 2.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: April 2, 2013
    Assignee: JX Nippon Oil & Energy Corporation
    Inventors: Tsutomu Takashima, Akira Shiibashi
  • Publication number: 20130030211
    Abstract: A bicyclohexane derivative compound useful in the field of photoresist, the field of intermediate of drugs and pesticides, and the like, and a manufacturing method of the same are provided. A bicyclohexane derivative compound represented by the following general formula (II) is provided. (In formula (II), Y independently represents an alkyl group of 1 to 10 carbons, a halogen atom, an acyloxy group, an alkoxycarbonyl group or a hydroxyl group, X1 represents a halogen atom, m represents an integer of 0 to 11, and m represents an integer of 0 to 10.
    Type: Application
    Filed: January 13, 2011
    Publication date: January 31, 2013
    Inventors: Masatoshi Echigo, Dai Oguro
  • Patent number: 8334363
    Abstract: Oxidized and maleated compositions, such as oxidized and maleated tall oil compositions, can be prepared and used in a variety of industrial applications, including as emulsifiers and corrosion inhibitors.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: December 18, 2012
    Assignee: Georgia-Pacific Chemicals LLC
    Inventors: Phillip W. Hurd, Gary D. Fultz, Brett A. Neumann, John B. Hines
  • Publication number: 20120071528
    Abstract: The invention is directed to novel compounds of Formula I: as well as its stereoisomers and/or pharmaceutically acceptable salts, for the treatment of diabetes and diabetes associated dyslipidemia.
    Type: Application
    Filed: September 20, 2011
    Publication date: March 22, 2012
    Applicant: KAREUS THERAPEUTICS, SA
    Inventors: Ish Khanna, Sivaram Pillarisetti
  • Publication number: 20120065320
    Abstract: A fluorine-containing polymer obtained using a 1,6-diene ether compound represented by formula [1] is a high-performance polymer exhibiting a low refractive index, high glass transition point, a high degree of transparency, and solubility in solvents. There are many potential uses, such as use as a coating material or bulk material. For example, said polymer could be effectively used in high-tech fields such as: optical materials such as low-reflection films and optical waveguide cladding; semiconductor materials such as pellicles and resists in semiconductor lithography; and protective film materials, insulating film materials, and water-repellent materials. (In the formula, R1 represents a C6-18 aryl group or a C1-12 alkyl group, which may be substituted.
    Type: Application
    Filed: May 18, 2010
    Publication date: March 15, 2012
    Applicants: NISSAN CHEMICAL INDUSTRIES, LTD., IBARAKI UNIVERSITY
    Inventors: Toshio Kubota, Ko-ichi Yanai, Takehiro Nagasawa, Akira Hirooka, Makoto Hirooka, Eiko Hirooka
  • Patent number: 8058480
    Abstract: Processes for the alkoxylation of alcohols using alkylene epoxides in the presence of boron based catalysts are provided.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: November 15, 2011
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Kenneth Gene Moloy
  • Patent number: 8058481
    Abstract: Described is a process for the alkoxylation of alcohols with I, Cl, or CH3CO2 endgroups, using alkylene epoxides in the presence of boron based catalysts.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: November 15, 2011
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Kenneth Gene Moloy, James A. Schultz
  • Publication number: 20110255048
    Abstract: The present invention relates to liquid-crystal (LC) media for use in LC displays of the PS (polymer stabilised) or PSA (polymer sustained alignment) type.
    Type: Application
    Filed: November 26, 2009
    Publication date: October 20, 2011
    Applicant: Merck Patent Gesellschaft MIT Beschraenkter Haftung
    Inventors: Achim Goetz, Melanie Klasen-Memmer, Stepham Derow
  • Publication number: 20110193020
    Abstract: The invention relates to a liquid-crystalline medium of negative dielectric anisotropy based on a mixture of polar compounds, which comprises at least one compound selected from the group of the compounds of the formulae IA, IB and IC in which R1A, R2A, R1B, R2B, R1C, R2C, L, m, n, o, p and b have the meanings indicated in Claim 1, and to the use thereof for an active-matrix display, in particular based on the ECB, PALC, FFS or IPS effect.
    Type: Application
    Filed: August 7, 2008
    Publication date: August 11, 2011
    Inventors: Melanie Klasen-Memmer, Matthias Bremer, Kazuaki Tarumi
  • Publication number: 20100291299
    Abstract: Cyclopentadienyl and Indenyl barium/strontium metal precursors and Lewis base adducts thereof are described. Such precursors have utility for forming Ba- and/or Sr-containing films on substrates, in the manufacture of microelectronic devices or structures.
    Type: Application
    Filed: August 3, 2008
    Publication date: November 18, 2010
    Applicant: ADVANCED TECHNOLOGY MATERIALS, INC.
    Inventors: Thomas M. Cameron, Chongying Xu
  • Publication number: 20100272925
    Abstract: Disclosed are liquid-crystal (LC) media for use in LC displays of the PS (polymer stabilised) or PSA (polymer sustained alignment) type which contain a liquid-crystal (LC) mixture that contains one or more compounds of formula I
    Type: Application
    Filed: April 23, 2010
    Publication date: October 28, 2010
    Applicant: MERCK PATENT GESELLSCHAFT
    Inventors: Achim Goetz, Melanie Klasen-Memmer, Stephan Derow, Sabine Schoen, Peter Best
  • Patent number: 7662852
    Abstract: An antiviral preparation comprising as an active ingredient, a phorbol derivative of formula 1: wherein is R1 is —(CH2)aX(CH2)bCH3, —(CH2)cX(CH2)dYCH3, —CO(CH2)eCH3 or —(CH2)fCH3 R2 is —CO(CH2)nCH3, R3, R4 and R5 are hydrogen atom, or an aliphatic or aromatic carboxylic acid residue, X and Y are O or S, and each of a-f and n is a number, and having a specific safety index S.I.=CC50/EC50 of 10 or more wherein EC50 means a concentration at which HIV-1 induced cytopathogenic effect (CPE) in MT-4 cell is inhibited by 50%, and CC50 means a concentration at which survival of MT-4 cell in a cell proliferation test is reduced by 50%. These preparations are particularly effective for human immuno-deficiency virus (HIV).
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: February 16, 2010
    Assignee: Lead Chemical Co., Ltd.
    Inventors: Masao Mori, Haruo Saito, Hideo Nemoto, Naoiki Yamamoto, Masao Hattori
  • Publication number: 20090309066
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of dielectrically negative, polar compounds which comprises at least one compound of the formula I in which the parameters have the meanings indicated in claim 1, to the use thereof in an electro-optical display, particularly in an active-matrix display based on the VA, ECB, PALC, FFS or IPS effect, and to displays of this type.
    Type: Application
    Filed: July 17, 2007
    Publication date: December 17, 2009
    Inventors: Melanie Klasen-Memmer, Georg Bernatz, Izumi Saito, Matthias Bremer, Lars Lietzau, Volker Reiffenrath
  • Patent number: 7615262
    Abstract: The present invention provides a liquid crystal material, method for producing the liquid crystal material, and liquid crystal device thereof which shows low light absorption in the ultraviolet light region. A compound of formula (I) wherein R is an alkyl or alkenyl group which is optionally interposed with one or more oxygen or sulphur atoms, Y is independently selected from oxygen or sulphur, n is an integer of from 2 to 8, X is a direct bond, C1-4alkylene or C2-4alkenylene, and A is selected from a various specified ring structures. The liquid crystal material (compounds) are of low birefringence and are U.V. stable and are useful in liquid crystal devices that need low birefringence such as reflective displays, or which are exposed to high levels of U.V. light such as phosphor display cells.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: November 10, 2009
    Assignee: Japan Science and Technology Agency
    Inventors: Neil Campbell, Jun Yamamoto, Hiroshi Yokoyama
  • Publication number: 20080266512
    Abstract: The present invention provides a liquid crystal material, method for producing the liquid crystal material, and liquid crystal device thereof which shows low light absorption in the ultraviolet light region. A compound of formula (I) wherein R is an alkyl or alkenyl group which is optionally interposed with one or more oxygen or sulphur atoms, Y is independently selected from oxygen or sulphur, n is an integer of from 2 to 8, X is a direct bond, C1-4alkylene or C2-4alkenylene, and A is selected from a various specified ring structures. The liquid crystal material (compounds) are of low birefringence and are U.V. stable and are useful in liquid crystal devices that need low birefringence such as reflective displays, or which are exposed to high levels of U.V. light such as phosphor display cells.
    Type: Application
    Filed: July 15, 2005
    Publication date: October 30, 2008
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Neil Campbell, Jun Yamamoto, Hiroshi Yokoyama
  • Patent number: 6939845
    Abstract: The present invention provides a fragrance precursor of formula I: that is capable of forming a fragrant ketone of formula II: and a fragrant lactone of formula III:
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: September 6, 2005
    Assignee: Givaudan SA
    Inventors: Markus Gautschi, Caroline Plessis, Samuel Derrer
  • Patent number: 6875894
    Abstract: The invention relates to bis(alkylthio)carbenium salts of the formula I with the stated definitions for R1, R2, R3 and Y?, and to a process for the preparation thereof. The compounds according to the invention are advantageously suitable as electrophilic reagents for the transfer of fluorinated alkyl and acyl radicals onto nucleophilic compounds.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: April 5, 2005
    Assignee: Merck Patent GmbH
    Inventors: Peer Kirsch, Andreas Ruhl, Gerd-Volker Röschenthaler, Dmitrii Sevenard
  • Publication number: 20040149957
    Abstract: The use of a compound of formula (I) 1
    Type: Application
    Filed: March 31, 2004
    Publication date: August 5, 2004
    Inventors: Stephen M Kelly, Neil L Campbell, Warren L Duffy
  • Patent number: 6720463
    Abstract: The present invention provides a process for producing an alkanediol derivative represented by the general formula (II) from an ester compound represented by the general formula (I), safely without giving rise to racemization. The present invention lies in a process for producing an alcohol derivative represented by the following general formula (II): (wherein R2 and R3 are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; X is a hydrogen atom or a protecting group for hydroxyl group; and n is 0 or 1), which process comprises reducing an ester compound represented by the following general formula (I): (wherein R1 is an alkyl group having 1 to 4 carbon atoms; and R2, R3, X and n have the same definitions as given above) with sodium borohydride in a mixed solvent of at least one kind of solvent selected from the group consisting of aromatic hydrocarbons, aliphatic hydrocarbons and alicyclic hydrocarbons and a primary alcohol.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: April 13, 2004
    Assignee: Ihara Chemical Industry Co., Ltd.
    Inventors: Yoshikazu Kimura, Yukio Uchida, Shuichi Fujimoto
  • Patent number: 6657089
    Abstract: This invention relates to a palladium catalyst comprising a mesoporous aluminosilicate which has been treated with ammonia or a salt thereof, and palladium supported on said mesoporous aluminosilicate; and also to a process for producing an ether, which comprises reacting a cyclic acetal and hydrogen in the presence of the palladium catalyst.
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: December 2, 2003
    Assignee: Kao Corporation
    Inventors: Atsushi Nagasawa, Munehisa Okutsu, Tomohito Kitsuki
  • Patent number: 6642424
    Abstract: Intermediate compounds, including 2-(t-butyldimethylsilyloxymethyl)-3,4-[(dimethylmethylene)dioxy]-5-hydroxy-tricyclo[5.2.1.02,6]dec-8-ene, which are useful for the synthesis of neplanocin A having strong antitumor activity. Improved processes for the preparation of neplanocin A, starting from optically active 2-hydroxymethyl-5-hydroxy-tricyclo[5.2.1.02,6]deca-3,8-diene and via a key step comprising a retro-Diels-Alder reaction of the above intermediate.
    Type: Grant
    Filed: May 7, 2001
    Date of Patent: November 4, 2003
    Assignee: Chisso Corporation
    Inventors: Naoyuki Yoshida, Kunio Ogasawara
  • Patent number: 6624335
    Abstract: An ether compound of formula (1) is provided wherein R1 is H or C1-6 alkyl, R2 is C1-6 alkyl, R3 is H, C1-15 acyl or C1-15 alkoxycarbonyl which may be substituted with halogen atoms, k is 0 or 1, m is from 0 to 3, and n is from 3 to 6. The ether compound is polymerized to form a polymer having improved reactivity, robustness and substrate adhesion.
    Type: Grant
    Filed: January 16, 2002
    Date of Patent: September 23, 2003
    Assignee: Shin Etsu Chemical Co., Ltd.
    Inventors: Seiichiro Tachibana, Mutsuo Nakashima, Tsunehiro Nishi
  • Publication number: 20030171620
    Abstract: The present invention relates to an improved process for preparing 4-(6-bromohexyloxy)-butylbenzene by reacting 4-phenylbutanol with 1,6-dibromohexane in the presence of a base and a phase transfer catalyst, wherein 4-phenylbutanol in a diluent is metered into a mixture consisting of 1,6-dibromohexane, a base, a phase transfer catalyst and a diluent, and the use of the 4-(6-bromohexyloxy)-butylbenzene thus prepared for producing salmeterol in a method known per se.
    Type: Application
    Filed: March 4, 2003
    Publication date: September 11, 2003
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Oliver Meyer, Helmut Heitger
  • Publication number: 20030158448
    Abstract: The present invention pertains to glycidyl ether-capped acetylenic diol ethoxylates having a structure according to the formula: 1
    Type: Application
    Filed: January 30, 2002
    Publication date: August 21, 2003
    Inventor: Kevin Rodney Lassila
  • Patent number: 6562782
    Abstract: The present invention related to an oligocycloalkanoid compound comprising formula (I) wherein m, n, and o are independently an integer from 0 to 2; A1 through A10 are independently a direct link, alkylene, alkylene-O—, carbonyl, oxygen, or sulfur; X and Y are independently hydrogen, hydroxy, alkyl, or in combination an electrophilic group; and R1 through R10 are independently hydrogen, hydroxy, alkyl, alkenyl, alkynyl, substituted or unsubstituted aryl, N-, S-, or O-heterocycles, fused or multi-ring aryl with or without hetero ring members, arylalkyl, arylalkenyl, arylalkynyl, alkylphenyl, alkenylphenyl, alkynylphenyl, alkoxy, alkenyloxy, alkynyloxy, substituted or unsubstituted aryloxy, substituted or unsubstituted arylalkoxy, alkylacyl, alkenylacyl, alkynylacyl, arylacyl, aroyl, alkylaroyl, aminoaroyl, aminoalkylacyl, aminoalkyl, aminoalkenyl, aminoalkynyl, amino, alkylamino, alkenylamino, alkynylamino, arylamino, dialkylamino, dialkenylamino, dialkynylamino, arylalkylamino, arylalk
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: May 13, 2003
    Assignee: University of Rochester
    Inventors: Benjamin L. Miller, Robert D. Hubbard
  • Patent number: 6548715
    Abstract: A compound of the formula I: in which P is hydrogen or alkyl; Y and Y′ are each hydrogen or, when taken together, represent a group ═CH2; W and W′ are each hydrogen; X is selected from the group consisting of a hydroxyalkyl, a hydroxyalkoxy, an alkoxy optionally comprising an epoxide function, a hydroxyalkene, a hydroxyalkadiene, a hydroxyalkyne and isomeric forms thereof; and a) either R1 and R3 or R′3 form a saturated 5- or 6-membered carbocyclic ring and R2, R′2, R3 or R′3, R4, R′4, R5 and R′5 are each independently hydrogen or alkyl; or b) R2 or R′2 and R4 or R′4 form a saturated 5- or 6-membered carbocyclic ring, and R1, R2 or R′2, R3, R′3, R4 or R′4, R5 and R′5 are each independently hydrogen or alkyl; or c) R3 or R′3 and R5 or R′5 form a saturated or unsaturated 5- or 6-membered carbocyclic ring, and R1, R2, R′2, R3 or R′3, R4, R′4, and R5 or R′5 are each indep
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: April 15, 2003
    Assignee: Laboratoire Theramex S.A.
    Inventors: Roger Bouillon, Maurits Vandewalle, Pierre Jean De Clercq
  • Patent number: 6465059
    Abstract: The invention relates to a liquid-crystalline medium one or more compounds of the general formula IA and one or more compounds of the formula IB R, R*, R**, z, L and Y are defined herein.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: October 15, 2002
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Matthias Bremer, Georg Lüssem, Dagmar Klement
  • Patent number: 6444858
    Abstract: The present invention provides a method for alkoxylating organic compounds comprising contacting an organic compound adapted to be alkoxylated with an alkylene oxide in a reaction vessel under conditions effective to alkoxylate the organic compound. The alkylene oxide is maintained in vapor form during transport to said reaction vessel, during discharge into said reaction vessel, and during contacting of the organic compound with the alkylene oxide. The result is an alkoxylated product containing less flocculant.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: September 3, 2002
    Assignee: Baker Hughes Incorporated
    Inventor: Philip Leung
  • Patent number: 6410802
    Abstract: The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: June 25, 2002
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Henri Dasseux, Carmen Daniela Oniciu
  • Patent number: 6365771
    Abstract: Decane compound or decene compound shown in the formula [1] below wherein A1 and A2 are independently hydrogen or (meth)acryloyl group or 2-vinyloxyethyl group; and the dotted line is single bond or double bond with the proviso that A1 and A2 are not hydrogen at the same time; and curable resin composition containing said compound therein. The compound are suitable as the photo-monomer for resist raw materials because of high clarity at short wavelength ultraviolet light, dry etching resistance, adhesive property for the substrate and high solubility in alkaline developing solution in addition to high sensitivity and greater resolution; as the monomer for optic raw materials and disk overcoat materials because of high clarity, low birefringence and low water absorption rate; and as the monomer for the coating raw materials such as EB curable coating raw materials because of high reactivity, high wear characteristics and water resistance.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: April 2, 2002
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Hideo Suzuki, Takayasu Nihira, Shinichiro Takigawa
  • Patent number: 6359153
    Abstract: The present invention relates to monomers for preparing photoresist polymer resins which can be used in a photolithography process employing a deep ultraviolet light source, and the preparation of the same. Preferred monomers are represented by following Chemical Formula 1: <Chemical Formula 1> wherein, X represents CH2, CH2CH2, or oxygen; R1 represents hydrogen, C1-C5 alkyl, or R′OH; R2 represents hydrogen; —OH, C1-C5 alkoxy, or —OR′—OH; R′ represents:  and, m is an integer from 1-5, n is 1 or 2 and p is 0 or 1.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: March 19, 2002
    Assignee: Hyundai Electronics Industries Co., Ltd.
    Inventors: Geun Su Lee, Chang Il Choi, Hyeong Soo Kim, Jin Soo Kim, Jae Chang Jung, Min Ho Jung, Ki Ho Baik
  • Patent number: 6319889
    Abstract: The invention is directed to novel compounds selected from the class of compounds having the structural formulae wherein the cyclohexane moiety with the dotted circle represents either a cyclohexane ring or a benzene ring, n represents an integer with the value 1, 3, or 4, m represents an integer with the value 1 or 2, R1, R2, R3, R4 and R5, represent hydrogen or a lower alkyl group, and the total carbon number of R1, R2, R3, R4 and R5, combined is eight or less.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: November 20, 2001
    Assignee: PFW Aroma Chemicals B.V.
    Inventors: Willem Lenselink, Anton Pieter Johan van Manen
  • Patent number: 6211416
    Abstract: Enol ethers of the formula I where R1 is an aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic radical which may carry further substituents which do not react with acetylenes or allenes, and the radicals R, independently of one another, are hydrogen or aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic radicals, which may be bonded to one another to form a ring, and m is 0 or 1, are prepared by reacting an acetal or ketal of the formula II with an acetylene or allene of the formula III or IV where R and R1 have the abovementioned meanings, in the gas phase at elevated temperatures in the presence of a zinc- or cadmium- and silicon- and oxygen-containing heterogeneous catalyst.
    Type: Grant
    Filed: December 6, 1999
    Date of Patent: April 3, 2001
    Assignee: BASF Aktiengesellschaft
    Inventors: Joaquim Henrique Teles, Norbert Rieber, Klaus Breuer, Dirk Demuth, Hartmut Hibst, Heinz Etzrodt, Udo Rheude
  • Patent number: 6133471
    Abstract: A process for producing chromans, comprising reacting a phenol, a formaldehyde and an alcohol in the presence of a secondary amine and an acid, to generate an alkoxymethylphenol compound with the ortho position to the phenolic hydroxyl group substituted with an alkoxymethyl group, and reacting the alkoxymethylphenol compound with an unsaturated compound having a carbon-carbon double bond.
    Type: Grant
    Filed: October 26, 1999
    Date of Patent: October 17, 2000
    Assignee: KURARAY Co., Ltd.
    Inventors: Hiroyuki Monoe, Junko Sato, Koichi Kanehira, Yoshin Tamai
  • Patent number: 6126857
    Abstract: The invention relates to bisalkenylbicyclohexanes of the formula I ##STR1## in which R.sup.1, R.sup.2 and Z are as defined in claim 1, and to their use in liquid-crystalline media.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: October 3, 2000
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Volker Reiffenrath, Harald Hirschmann
  • Patent number: 6093836
    Abstract: The present invention relates to a novel 1,3-diphenylpropane derivative having an inhibitory activity against tyrosinase represented by the following formula (I): ##STR1## in which - - represents double or single bond,R.sub.1 represents hydrogen or C.sub.1 -C.sub.10 alkyl,R.sub.2 represents C.sub.1 -C.sub.5 alkyl or C.sub.1 -C.sub.5 alkoxyalkyl, orR.sub.1 and R.sub.2 together represent a 5 to 6 membered heterocycle which can be substituted by C.sub.1 -C.sub.5 alkyl and which contains oxygen as the hetero atom,R.sub.3 represents hydrogen or C.sub.1 -C.sub.7 alkyl,R.sub.4 represents hydrogen, hydroxy, or oxo, andR.sub.5 and R.sub.6 mindependently of one another represent hydrogen or C.sub.1 -C.sub.5 alkyl.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: July 25, 2000
    Assignee: LG Chemical Ltd.
    Inventors: Young Ho Rhee, Kyung Ae Kim, Hyun Ho Lee, Jong Kwon Choi, Sang Hwa Lee
  • Patent number: 5728796
    Abstract: A process reaction between: (1) a compound that contains one or more epoxide moieties per molecule, and (2) a compound that contains one or more primary aliphatic hydroxyl groups per molecule; is catalyzed by: (3) a catalyst compound containing one or more trifluoromethanesulfonate moieties and one or more silyl moieties and run at a temperature of no more than 130.degree. C., such that the catalyst preferably catalyzes reaction at the primary aliphatic hydroxyl group, so that the resulting resin does not gel.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: March 17, 1998
    Assignee: The Dow Chemical Company
    Inventors: Zeng K. Liao, James L. Bertram