Abstract: An intraluminal device and method of deploying an intraluminal device in a portion of a lumen includes the device having a body with a wall defining a surface. The surface is configured to a portion of a lumen. An anchor system made up of a plurality of anchors fixes the body to an inner wall of the lumen. At least intermittent pressure with the surface to the inner wall of the lumen. A tissue fold of the inner wall of the lumen is formed. Thee tissue fold is adjacent the body wall and transmits a force between the inner wall of the lumen and the device body.

Abstract: An volume filling device for treatment of obesity is placed outside the stomach wall of the patient to reduce the inner volume of the stomach, thereby affecting the patient's appetite. By providing the volume filling device outside the stomach wall, contact with stomach acids is avoided, thereby increasing the life of the device.

Abstract: An obesity treatment device is provided, the device comprising: at least one operable stretching device implantable in an obese patient and adapted to stretch a portion of the patient's stomach wall and an operation device for operating the stretching device when implanted to stretch the stomach wall portion such that satiety is created.

Abstract: A bariatric clamp may include substrate members overmolded in polymer forming first and second elongated portions, a bight portion having a flexible hinge, one or more inflatable portions disposed at least partially along interior sections of the first and second elongated portions; and a port coupled to at least one of the inflatable portions and configured to adjust inflation of the inflatable portions. The inflatable portions are provided to assist in retaining the clamp in a closed position to partition the stomach and to adjust a pressure of the clamp when partitioning the stomach.

Abstract: Embodiments of the invention provide a retrieval device and method for retrieving tissue from a body cavity. The retrieval device includes a pouch having an aperture and a pouch wall defining an interior space. An inflatable rim is coupled to the pouch and facilitates retrieval of the tissue into the interior space of the pouch. The retrieval device further includes a closure device coupled to the pouch wall for enclosing the tissue within the interior space of the pouch. A portion of the pouch wall includes a self-sealing characteristic that allows an instrument to pierce the pouch wall and the pouch wall is resealable after withdrawal of the instrument. The pouch can move from a retracted position to a expanded position upon inflation of the inflatable rim, which can then be separated by application of a separation force at an area of material weakness in the pouch wall.

Abstract: An implant or sling sheath system having an overlapping sheath material is provided. The sheath can include two telescoping or overlapping sections. The overlapping sections can include at least one release feature to eliminate or reduce sticking of the overlapping sections together during use.

Abstract: The present invention provides a low-risk, unobtrusive and noninvasive method and device for treatment of obesity and eating disorders. In embodiments, the device is a gastric device suitable for placement in a stomach of a subject. The device may be composed of a sponge material which absorbs fluid upon implantation and expands in volume, thereby functioning as a space occupying device in the stomach to cause early satiety.

Abstract: Intragastric volume-occupying devices and methods for treating obesity are provided. The devices, which are inflated by carbon dioxide, include an aluminum or silicon oxide barrier layer providing carbon dioxide retention and an alkylene vinyl alcohol polymer layer providing structural integrity in vivo.

Abstract: Devices and methods for clamping tissue and/or moving two tissue structures together by moving two plates or arm together. The pressure or force applied to the tissue may be used to bring the tissue together, to seal an opening or to cut through and remove a portion of the tissue. In one procedure disclosed, a clip applier may be used to apply one or more clips to the left atrial appendage of the heart to prevent clots from the left atrial appendage from embolizing and causing harm to the patient, such as a stroke.

Abstract: Methods, devices and systems for delivering a device assembly into a gastric or other space within the body, allowing the device to expand to occupy volume within the gastric space and, after an effective period of time, delivering a substance or stimulus to begin breakdown of the expanded device so that it may release from the body.

Abstract: Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided.

Abstract: The present invention relates to the field of medical devices. Specifically, the invention relates to an enteral feeding device comprising expandable means which prevents or significantly reduces aspirations from the alimentary tract to the respiratory system. In further aspects, the invention relates to systems comprising said enteral feeding device, methods and uses thereof.

Abstract: Components may be used separately or in combination to create anchoring systems for intra-luminal implants for the treatment of metabolic disorders such as obesity and diabetes. Various systems include an external component adapted for deployment around a portion of the gastrointestinal tract (e.g., the duodenum) and an internal component adapted for implantation within the gastrointestinal tract. Various systems use anchors that are based on mechanical interference, elasticity, spring force, shape memory transformation, magnetic attraction, repulsion and/or levitation. Various embodiments rely on longitudinal anchoring of the implants with minimal force against tissue.

Abstract: An intragastric anchor implant device is provided with a substantially rigid member having proximal and distal ends and atraumatic tips or features disposed near the proximal and distal ends. The atraumatic features prevent damage to the tissues of the stomach and the gastrointestinal track and may help to anchor the device in the stomach, while the substantially rigid member resists bending so as to engage a tissue of the stomach or the gastrointestinal tract to prevent passage through the stomach. The anchor implant device is coupled with a therapeutic device, typically a sleeve, such as an intestinal bypass sleeve. Ideally, the device includes a sliding seal to direct a flow of food particles from the stomach through the sleeve, so as to be useful in treating a disorder, including obesity and diabetes. Methods of deploying the anchor implant devices are also disclosed.

Abstract: An implantable system comprises a housing that includes a flexible reservoir. The flexible reservoir is coupled to an inflatable portion of a gastric band via a fluid inlet/outlet. The flexible reservoir contains a fluid and has an expanded configuration and a contracted configuration. An access port may be coupled to the flexible reservoir and/or the gastric band to facilitate filling and draining the reservoir and/or the gastric band. A movable wall is slidably positioned around the flexible reservoir to move the flexible reservoir between the expanded configuration and the contracted configuration to move the fluid into and out of the inflatable portion of the gastric band. A driving mechanism is positioned around the movable wall and is capable of changing the size of the movable wall to compress or expand the flexible reservoir. A motor, coupled to the driving mechanism, may actuate the driving mechanism.

Abstract: A balloon-type gastric band includes a balloon shaped and dimensioned to circumscribe the stomach at a predetermined location. The balloon includes a longitudinally extending body. A supply tube is secured to the balloon for fluid communication with an internal cavity of the balloon, wherein the supply tube includes a valve controlling the flow of fluid to and from the balloon.

Abstract: An inflatable gastric band incorporates a fluid channel within an outer surface of the band and an inflatable bladder on a stomach-facing side of the band. The gastric band attaches to a double lumen catheter, which communicates with a dual infusion port. One lumen communicates with the fluid channel and one port, while the other lumen communicates with the inflatable bladder and a second port. Injection of fluid into one chamber of the infusion port expands inflatable bladder, allowing adjustment to the diameter of the stoma. Injection of drugs or therapeutic agents into the second chamber allows the infusion of drugs or agents directly into the abdominal cavity of a gastric band recipient. The inflatable bladder can be continuous or segmented. A segmented bladder reduces pinching and/or folding of the inner surface of the gastric band during expansion/contraction, thereby lessening stomach pinching and/or irritation.

Abstract: A balloon-type gastric band that includes a balloon and a belt secured to the balloon. The balloon includes a mechanism for contrasting the balloon from surrounding tissue when placed within a patient.

Abstract: A balloon-type gastric band includes a balloon shaped and dimensioned to circumscribe a stomach at a predetermined location. A supply tube is secured to the balloon for fluid communication with an internal cavity of the balloon, wherein the supply tube includes both at least one colored section and at least one clear section for respectively contrasting the supply tube from surrounding tissue when placed within a patient and facilitating identification of leaks within the supply tube. In accordance with an alternate embodiment the supply tube is colored while remaining translucent.

Abstract: In an adaptive device and an adaptive method for adapting the stomach opening of a patient, a gastric band having a non-elastic back part on the exterior and a first expandable chamber on the interior are placed around the stomach of the patient for adapting the stomach opening, and the stomach opening of the patient is adapted by modifying the amount of fluid in the first expandable chamber. For this purpose, the adaptive device includes a second expandable chamber, so that the second expandable chamber is connected to the first expandable chamber, and whereby the fluid is displaced from the one expandable chamber to the other expandable chamber in order to modify the stomach opening of the patient. The adaptive device can in particular be controlled by changing the position of the body of the patient.

Abstract: A gastric band has a balloon shaped and dimensioned to circumscribe the stomach at a predetermined location and a belt extending about the balloon. Further, a linking layer is positioned between the balloon and the belt, wherein the linking layer is harder than either the balloon or the belt. Additionally, the belt includes a first latching member at a first end of the gastric band and second latching member at a second end of the gastric band, the first latching member and the second latching member being shaped and dimensioned for selective engagement to secure the gastric band about a stomach of a patient, wherein the first latching member and second latching member are composed of different materials.

Abstract: The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Abstract: A gastric restrictor assembly for positioning within the digestive tract, e.g., stomach, of a patient to treat obesity is disclosed. The gastric restrictor assembly includes an attachment mechanism for attaching the assembly within a body lumen and a valve assembly for adjusting the diameter of a throughbore defined by valve assembly. The gastric restrictor includes first and second actuators which can be actuated transorally for operating the attachment mechanism and the valve assembly.

Abstract: In some embodiments, methods to sense parameters associated with restriction procedures and/or devices are disclosed. In some embodiments, the parameters are sensed directly from the region of the procedure and/or device and in other embodiments, associated neural pathways are sensed. Methods for further optimization of the obesity treatment regimens are also disclosed.

Abstract: Methods of treating obesity and/or type II diabetes include applying at least one stimulus to the pituitary gland of a patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat obesity and/or type II diabetes. Systems for treating obesity and/or type II diabetes include a stimulator configured to apply at least one stimulus to the pituitary gland of a patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat obesity and/or type II diabetes.

Abstract: A food intake restriction device for forming a restriction in a patient's gastro-intestinal tract and non-invasively communicating pressure data regarding the restriction to an external monitor. The device includes a food intake restriction device implanted substantially about a patient's gastro-intestinal tract to form a restricted opening in the tract. A port is connected to the restriction device. The port contains a working fluid for affecting the size of the restricted opening. A pressure sensing system communicates with the working fluid to measure the pressure of the working fluid. A transmitter communicates the measured fluid pressure to the external monitor.

Abstract: An intragastric catheter provides satiety due to its presence in the stomach cavity. Efficacy is improved by the tactile sensation provided by a plurality of fingers that extend from the device. Normal peristaltic action upon the device moves the fingers relative to the stomach. The structure of the intragastric catheter reduces the level of precision required in placement of the device, and blockage of conduits to and from the stomach by the device is unlikely.

Abstract: The invention relates to a gastroplasty ring formed by a flexible band (2) which comprises a first end part (5) and a second end part (6) and which is intended to be closed around the stomach toward its two end parts by a closure system in order to reduce the diameter of the opening of the stoma by forming a loop, the band comprising an adjustable-volume annular compression chamber (3) connected, at the first end part, by an adjusting catheter (7) to a device for adjusting the internal pressure of said chamber, so as to adjust its diametral expansion, the ring comprising at least one grab tab (11, 12, 13) which projects toward the outside of the loop to make it easier for the two end parts to be brought together and parted. Gastric implant for treating obesity.

Abstract: An implantable restriction device is configured to provide a restriction in a patient as a function of the pressure of fluid. The implantable restriction device includes one or more pressure sensors configured to sense pressure of the fluid within the implantable restriction device. Pressure data obtained by the one or more pressure sensors may be communicated to a device located external to the patient, which may process the pressure data, and may further provide a display to a user including information relating to the processed pressure data. Where the implantable restriction device comprises an adjustable gastric band, the one or more pressure sensors may be located in any number of the following locations: an injection port, an interface between the injection port and a catheter, in a catheter, in-line with a catheter, adjacent to a catheter, in a gastric band, in a gastric band buckle, or elsewhere.

Abstract: In some embodiments, methods to sense parameters associated with restriction procedures and/or devices are disclosed. In some embodiments, the parameters are sensed directly from the region of the procedure and/or device and in other embodiments, associated neural pathways are sensed. Methods for further optimization of the obesity treatment regimens are also disclosed.

Abstract: A method for remote and nonconnected interaction between an implant having an electrical motor and a transmitter/receiver inverter having an induction source having/connected to a power source for operating the electrical motor including creating modifications in an electromagnetic field by the transmitter/receiver inverter, and transmitting information in the form of binary data from the transmitter/receiver inverter to the implant; and a device for remote and nonconnected interaction with an implant having a transponder including an induction source having/connected to a power source, and means enabling the induction source to create modifications in an electromagnetic field generated in the device to transmit information in the form of binary data to the implant.

Abstract: This invention provides a method and system for the curative treatment of obesity. A first aspect of this invention is that it enables identification of the nerves responsible for the relaxation of the stomach muscles that occurs prior to and during eating. A second aspect of the invention is that it allows the physician to identify focal nerve sites in the stomach and upper duodenum that are associated with producing sensations of hunger and satiety. Nervous transmission from these sites can be modulated or blocked all together so as to minimize the sensation of hunger. A third aspect of this invention is that allows a physician to shrink selected portions of the innermost oblique muscle and middle circular muscle layers of the stomach. This can be performed in a physician's office using local anesthesia. Shrinkage of these muscles produces a feeling of satiety that enhances the patient's efforts to restrict his caloric intake.

Abstract: An intragastric catheter provides satiety due to its presence in the stomach cavity. Efficacy is improved by the tactile sensation provided by a plurality of fingers that extend from the device. Normal peristaltic action upon the device moves the fingers relative to the stomach. The structure of the intragastric catheter reduces the level of precision required in placement of the device, and blockage of conduits to and from the stomach by the device is unlikely.

Abstract: An intragastric catheter provides a method of inducing satiety due to its presence in the stomach cavity. Efficacy is improved by the tactile sensation provided by a plurality of fingers that extend from the device. Normal peristaltic action upon the device moves the fingers relative to the stomach. The structure of the intragastric catheter reduces the level of precision required in placement of the device, and blockage of conduits to and from the stomach by the device is unlikely.

Abstract: A surgical tool for safely introducing a gastric band into a patient's abdomen is provided. The instrument includes an inner rod slidably and coaxially disposed within a support tube. The inner rod includes a gastric band releasably secured thereon. Distal movement of the inner rod into the support tube exposes said gastric band.

Abstract: A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

Abstract: A gastroplasty ring having a single control is provided and includes a flexible strip with two ends for being closed around the stomach by a closure system so as to reduce the diameter of the opening of the stoma. The strip may have an annular compression chamber of adjustable volume and of substantially constant section connected by an adjustment catheter to a device for adjusting the internal pressure in the chamber so as to adjust its diametral expansion. The closure system may be used for reversibly locking and loosening the ring, and for releasing the diameter of the ring momentarily by relative displacement between the two ends, while continuously forming a closed loop around the stomach. The ring constitutes a gastric implant for treating obesity.

Abstract: A device for generating an artificial constriction in the gastrointestinal tract comprises a band (1), which can be placed annularly about a particular portion of the gastrointestinal tract, and a closure device (2) for connecting the end regions of the band (1) placed annularly about a portion of the gastrointestinal tract, the band in the closed state of the closure device (2) encompassing a throughlet opening (6), the band (1) including a hollow chamber (13) fillable with a filling medium and extending at least over a large portion of the length of the band (1) and delimited on its side, facing the throughlet opening (6), by a diaphragm (11), by means of which the size of the throughlet opening (6) can be decreased by filling the hollow chamber (13).

Abstract: In arrangement for supporting a counter pressure plate of a shaft-like surgical clamp suturing instrument for establishing a circular seam, a shaft-like clamp suturing instrument having at its distal end a support and guide structure and a one-piece support structure axially movably supported on the support and guide structure and having a support portion extending normal to the shaft section and releasable engaging a back-pressure plate in a position where the back-pressure plate is in axial alignment with the shaft section.

Abstract: In the treatment of morbid obesity or heartburn and reflux disease an elongated restriction member (12) is formed in a substantially closed loop around a human's stomach or esophagus to form a stoma opening in the stomach or esophagus. The size of the stoma opening is adjustable by an implanted adjustment device. A control device (22) is utilized to control the adjustment device, in order to either reduce or enlarge the size of the stoma opening, for example in response to the time of the day. Nausea in a treated obese human can be minimized or substantially eliminated as a result of the control device controlling the adjustment device to keep the stoma opening substantially fully open between meals (such as at night when the human is sleeping).

Abstract: An adjustable gastric banding device is used for contracting a patient's stomach in order to fight obesity. A gastric band (1) of a known type, implanted around the stomach and including a cavity (2) filled with liquid, is connected by a tube (7) to a control box (9) and a balancing reservoir (11) which are implanted under the patient's skin. The box (9) contains an electric pump and an electronic control unit capable of communicating by radio with a monitor (13) carried by the patient and with a controller (12) intended for the doctor. The controller can operate the pump by remote control to transfer determined volumes of liquid in a closed circuit from the gastric band to the reservoir or vice versa, to adjust the diameter of a passage in the stomach. The monitor receives and signals alarms from the control box.

Abstract: An endoscopic stomach insert for treating obesity in humans by reducing the desire for eating, comprising a base-sized for passing through a human mouth and esophagus; a plurality of flexible blades coupled at one end thereof to the base and circumferentially arranged about the base central axis, where the blades are biased to extend substantially radially outward and downward from the base; and a retainer for releasably coupling the distal portions of the blades within close proximity to each other about the central axis of the base. The insert is thus adapted to be passed through the mouth and esophagus and into a human stomach, and upon releasing the retainer within the stomach, the blades are biased to flare outwardly into the form of a dome-shaped cage, applying pressure to the stomach, and thus causing a sensation of fullness within the stomach and reducing the desire for eating.