Abstract: A hand-held aspiration device is provided which has a relatively small suction volume along a suction path to improve responsiveness of the aspiration device when the device is activated. The device may be manually powered and may be provided without electronic controls. The device has a suction path which may be purged into a disposal enclosure to reduce the volume of material under the influence of the suction pressure during the procedure. The suction source may also be part of the hand-held unit to further reduce the suction path and suction volume.

Abstract: Methods and apparatus for retracting the dura away from a cutting tool during a laminectomy procedure. The method includes inserting a memory shape surgical sponge (patty) into an initial epidural space between the dura and the tool used to decompress (e.g., drill) the lamina. As the lamina is further decompressed, the patty tends to spring back toward its nominal position, urging the dura away from the decompression and isolating the dura from the drill.

Abstract: An IOL base compression device having an IOL towing mechanism is described.

Abstract: An intraocular lens (IOL) injector is configured for single hand operation and employs a compressed gas to provide a motive force to present an IOL to a surgical site. The IOL injector includes a mechanical brake coupled to a plunger to preclude translation of an IOL absent operator input. The mechanical brake provides for selectively varying the speed and translation of the plunger, and hence IOL during presentation of the IOL to a patient. The IOL injector can also include at least a first stop, which halts movement of the plunger at a predetermined position. The at least first stop is then moved to a passing position, thereby allowing further operator controlled translation of the plunger to present the IOL to the surgical site.

Abstract: An injector for ejecting an intraocular lens for injecting the latter into an eye or for implanting a corneal endothelial tissue, including an elongate injector body which has a piston rod passage and in which an injector piston rod having a screw thread is guided in a longitudinally displaceable manner. The injector is provided with two operating modes for the displacement of the injector piston rod and is able to be switched between the modes. The first operating mode defines an ejection operation and the second operating mode defines a screwing operation. The injector body has at least one retractable and deployable wing grip, wherein the operating mode is set to ejection operation by the deployed position and the operating mode is set to screwing operation by the retracted position. The injector piston rod includes a stop element.

Abstract: A corneal implant injector system includes an injector including a plunger slidable in a plunger housing, and a distal cartridge grabbing member engageable with an implant-holding cartridge.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An example optic management system may include a housing having a first end and a second end and a first side extending between the first end the second end. The housing may include a cavity formed in the first side of the housing and configured to accommodate an intraocular lens, wherein the cavity comprises a first end portion, a second end portion, and a central portion. The housing may further include a bore formed in the housing, wherein a first portion of the bore extends from the first end to the cavity. The haptic optic management system may further include a ceiling disposed on the first side of the housing. The haptic optic management system may further include arms pivotably coupled to the housing in the cavity.

Abstract: Embodiments of apparatuses and methods for microfracture (e.g., forming a plurality of microfractures in a bone to encourage cartilage regeneration).

Abstract: The Nucleo-reticular Multi-cell Dual-system Eye Implant consists of a spherical structure with calculated and variable axial length depending on the needs required by the orbital eye socket, composed of a cell mesh with alternative designs that in turn, makes up the MMM System, in which suturing is provided in any technique, either in cases of evisceration or enucleation. Thanks to its multi-cell structural design, it favors its placement and reduces the risk of migration, extrusion, exposure and extraction. As it is an arrangement with structural holes, it provides a higher percentage of the volume for its vascularization; it also houses inside a Reticular Fibrovascular Core System, which has a structure based on multilevels equipped with micro-reticular tissue and an intra-level communication based on filaments; with the capacity to contain medicines and/or technology by presenting a dual-system of two screw-on pieces, being able to manufacture in different structural designs and biocompatible materials.

Abstract: Systems, methods, and apparatuses for removably attaching a drive mechanism handpiece to an intraocular lens (IOL) cartridge that folds the IOL upon removal of a cap, are provided. The IOL cartridge comprises a nozzle and a housing comprising a slide. A compartment configured to receive an IOL is disposed within the housing. An interior portion of the slide is exposed to the compartment. The nozzle is in fluid communication with the compartment. The cap covers the nozzle and the slide. The cap is configured to expose the nozzle and advance the slide to fold the IOL upon removal of the cap.

Abstract: A device for delivering a treatment medium to an eye includes a first body portion configured to be removably inserted and secured in an opening of the eye, and a second body portion supported by the first body portion. At least the second body portion includes a treatment medium, and a coating having an opening through which the treatment medium elutes out of the device.

Abstract: An IOL injector plunger having IOL compression arms is described.

Abstract: An intraocular lens insertion device which dramatically reduces the possibility that a plunger damages an intraocular lens, and which can safely and surely insert an intraocular lens into an eye is provided. An intraocular lens insertion unit comprises a lens disposing part for disposing an intraocular lens, a plunger for pushing out the intraocular lens disposed at the lens disposing part, a transition part for deforming the intraocular lens pushed out by the plunger, and a nozzle for ejecting the deformed intraocular lens. The plunger has a lens contact part for contacting the outer edge of the intraocular lens, and a protrusive part for pushing the lens contact part downward the intraocular lens by the deformation of the intraocular lens, both lens contact part and protrusive part are provided at the leading end of the plunger.

Abstract: A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.

Abstract: Devices, systems, and methods for performing an ophthalmic procedure in an eye are disclosed. The devices include a hand-held portion and a distal, elongate member coupled to the hand-held portion having a lumen operatively coupled to a vacuum source. A drive mechanism operatively coupled to the elongate member is configured to oscillate the elongate member. When in use, the device is configured to aspirate ocular material from the eye through the lumen. The drive mechanism retracts the elongate member with a retraction speed profile and advances the elongate member with an extension speed profile. The retraction speed profile is different from the extension speed profile.

Abstract: A device is described herein for performing capsulotomies that improves temperature uniformity and current flow around a cutting element of the device. The device includes a series of features whose geometries help remove cold and/or hot spots from the cutting element while maintaining the mechanical strength of the cutting element. In an embodiment, a device includes a cutting element and one or more electrical leads for providing an electrical discharge to the cutting element. The device further includes wire tabs configured to conductively couple an electrical lead to cutting element. Each wire tab includes a central conductive path and one or more conductive shunt paths conductively separated by one or more slots. The device further includes anchor tabs that are each associated with a slot disposed along the circumference of the cutting element and positioned to at least partially separate an anchor tab from a portion of the cutting element.

Abstract: Embodiments of the invention provide hydrodissection and/or PCO prevention or reduction in a patient undergoing eye surgery. In one embodiment, the invention is a surgical device for cutting and excising a portion of tissue, for example in performing a lens capsulotomy. A capsulotomy tip is inserted into an eye through an incision in the surface of the eye. The capsulotomy tip includes a suction cup to provide suction to the lens capsule. Then suction is applied via the suction cup to secure the capsulotomy tip to the eye. In some embodiments, after the capsulotomy tip is secured to the lens capsule, a cutting element of the capsulotomy tip is used to cut a tissue of the eye. Fluid is pushed through the capsulotomy tip and the capsulotomy tip is removed from the eye. Moreover, disclosed is an intraocular lens (IOL) to be used in conjunction with the surgical device.

Abstract: The invention relates generally to the fields of biology and health sciences. More particularly, the invention relates to compositions and methods for modulating cellular physiology and pathological processing using a combination of compounds that can be found in amniotic membrane tissue and umbilical cord tissue preparations.

Abstract: A method of controlling an eye surgical laser is disclosed for the separation of a volume body with predefined posterior and anterior interfaces from a human/animal cornea. The method including controlling the laser with a control device, the laser being configured to emit pulsed laser pulses in a predefined pattern into the cornea. The posterior and anterior interfaces of the volume body are defined by the predefined pattern and are generated by an interaction of the individual laser pulses with the cornea through photodisruption. The control device controls the laser beam such that both interfaces are generated via a continuous, uninterrupted sequence of laser pulses. A treatment device is disclosed with at least one eye surgical laser for the separation of a predefined corneal volume with predefined interfaces of a human/animal eye by photodisruption and with at least one control device for the laser(s).

Abstract: The present disclosure provides devices and methods for the treatment of ophthalmological conditions such as dry eye. Among the devices provided are punctal plugs and devices for inserting punctal plugs. The punctal plugs may be shaped for insertion in the punctum and/or the canaliculus. They may also be coated with a bioadhesive. Methods for inserting the punctal plugs are provided, as well as methods for preparing bioadhesive-coated punctal plugs. A method is also provided to treat dry-eye using a bioadhesive without use of a punctal plug.

Abstract: An IOL delivery device which has a macro movement actuator which is actuateable to move an IOL into position in the device for the IOL to be delivered, and a micro movement actuator comprising at least one pivotable member which is pivotable to deliver the IOL to the eye. The pivotable member may comprise one or more wheels that are rotatable using one's finger.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) into an eye may be provided. An example haptic optic management system may comprise a first cam assembly comprising a first cam body portion, an opening in the first cam body portion, and haptic folder arms disposed in the opening. The haptic optic management system may further comprise a second cam assembly positioned on one side of the first cam assembly, wherein the second cam assembly comprises a second cam body portion, an opening in the second cam body portion, and optic folders disposed in the opening. The haptic optic management system may further comprise a central plate for holding an intraocular lens in the opening of the second cam body portion, wherein the central plate is disposed between the first cam assembly and the second cam assembly.

Abstract: A vibrating tissue separator suitable for use in separating a lenticule established by a femtosecond laser during a smile procedure may include a surgical implement such as a blunt spatula mounted on a handle that carries a haptic actuator for applying vibratory motion to the surgical implement. A damping arrangement may be provided to isolate the surgeons hand from the vibrations which would otherwise be transmitted through the handle. The actuator may apply a linear vibration along the axis of the handle which applies a lifting and chopping motion to the tip of a surgical implement having a bend. The tip may be suitable to the tissue being separated. For example, for SMILE lenticule separation, a blunt or semi-sharp spatula, blunted wire or loop may be used. The direction of vibration at the tip may be changed by rotating the implement in a plane other than the plane of the bend or by rotating an actuator such as an LRA with respect to the handle.

Abstract: Intraocular lens (IOL) folding devices and methods of folding an IOL or components thereof are disclosed.

Abstract: To provide an intraocular lens to which a mark for assisting more accurate fixation in an eye has been applied. Provided is an intraocular lens including an optical part having a mark that is detectable under illumination of a specific wavelength range outside a wavelength range of visible light, and a support part that supports the optical part, in which the mark is indicated by a geometric pattern that allows for identification of an optical center position of the optical part and information regarding posture of the optical part in an eye.

Abstract: Provided is an injector assembly, comprising: —an injector, which has a plunger and a cannula and is designed to move an intraocular lens through the cannula by means of a translational motion of the plunger; —a magnetic coupling; and—a drive unit, which has a first coupling half of the magnetic coupling, a motor, which is designed to drive the first coupling half into a first rotational motion, and a housing, within which the first coupling half and the motor are encapsulated and which has an annular housing portion, which delimits a channel having a circular cross-section. The injector has a second coupling half of the magnetic coupling, and the injector and the second coupling half are arranged in the channel.

Abstract: Provided herein are vitrectomy instruments and related systems and methods in which the vitrectomy instruments may include a forward needle stop and a cutter stop to reduce dimensional variation of a cutter of the vitrectomy instruments, allowing for a location of the port formed in a needle of the cutter to be positioned closer to a distal tip of the cutter. With the port located closer to a distal end of the cutter, the port is able to be positioned closer to the retina of an eye.

Abstract: An IOL injector having a collapsible mechanism and/or a lever-driven rack and pinion is described.

Abstract: An intraocular lens (IOL) insertion apparatus includes a handpiece body having a distal tip and a proximal section. The IOL insertion apparatus also includes a folding chamber located within the handpiece body, the folding chamber shaped to fold an IOL advancing through the folding chamber. The IOL insertion apparatus also includes an advancement system. The advancement system includes an advancement carriage movable between a first position and a second position within the handpiece body. The advancement carriage includes a spring system biasing the advancement carriage in a distal direction toward the second position and a dampening system to dampen motion of the advancement carriage. The advancement system further includes an elongated advancement plunger that includes a distal end to advance the IOL through the folding chamber and a proximal end connected to the advancement carriage.

Abstract: Apparatuses, systems, and methods for implanting an intraocular lens into an eye are described. For example, an intraocular lens injector may include a plunger and an injector body that includes an insertion depth guard and a nozzle extending therefrom. The insertion depth guard is disposed at a distal end of the injector body to limit a distance that the nozzle penetrates the eye. The intraocular lens injector may also include a biasing element configured to generate a counterforce to distal movement of the plunger through the injector rod. An example intraocular lens injector may include a biasing element to produce a counterforce that opposes advancement of the plunger through the injector body. The counterforce provides for a more continuous advancement of the plunger while reducing or substantially eliminating abrupt changes in the rate at which the plunger is advanced through the injector body.

Abstract: An apparatus for controlled perforation and aspiration of the inner ear.

Abstract: In a first aspect of the subject invention, an iris expander is provided which includes a non-metallic, unitary, multi-segmented body which is expandable from a first state to a second state. The second state defines a larger footprint than the first state with the body being defined by a plurality of segments connected by living hinges. In a further aspect, an iris expander is provided which includes a multi-segmented body that is expandable from a first state to a larger-footprint second state. At least one aperture is formed in the body with a channel extending therefrom embedded in the body such that no portion thereof is exposed externally of the body. The channel is formed to accommodate a portion of an instrument for causing adjustment of the body with avoidance of direct contact of the instrument with the tissue of the iris.

Abstract: Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include a plurality of implants, an external housing, and an introducer assembly. The external housing can provide access to an implant singulation actuator and an implant delivery actuator. The introducer assembly can comprise an auto-retracting introducer portion. The delivery apparatus can include an infinite activation mechanism/portion and/or a manual singulation mechanism/portion.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An apparatus for delivery of a lens component into an eye, including: a nozzle; a housing, wherein the nozzle is operatively coupled to the housing; a first lever; a second lever; and a linkage assembly. The linkage assembly may be disposed within the housing between and adjacent to the first and second levers. The linkage assembly may include a plurality of linkages pivotably coupled to each other, wherein the linkage assembly is collapsible.

Abstract: Systems, methods, and devices, for delivery of a lens portion of a modular intraocular lens into an eye, may be provided. A device may include a housing; a nozzle positioned at an end of the housing, wherein an interior of the nozzle comprises a floor, the floor including an aperture; and a cam-actuated mechanism positioned within the housing, comprising: a lens stop comprising a base and a post, wherein the post is movably disposed within the aperture; and a slider configured to move in a direction toward the lens stop, wherein the lens stop is positioned at a distal end of the slider, the slider comprising a slot that is aligned with a portion of the base of the lens stop and configured to receive the portion of the base as the slider moves.

Abstract: An ocular implant system including an ocular implant sized and shaped to be inserted at least partially into an eye; a carrier member with a shell having a central channel extending at least partially through the shell from a proximal end towards a distal end of the shell. A guide sleeve removably attached within at least a first region of the central channel of the shell and defining a proximal port into the central channel that is accessible from the proximal end of the shell. An implant holder removably attached within at least a second region of the central channel of the shell adjacent to a distal end of the guide sleeve and having a pair of graspers adapted to releasably secure the implant at a distal end of the implant holder. Related devices, systems, and/or methods are described.

Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. A device for delivery of the IOL into the eye may include a nozzle; a bay adjacent to the nozzle, wherein the bay is configured to contain the lens component and comprises a recess in a shape of a haptic extension; and a cam-actuated mechanism comprising a slider configured to move in a direction toward the nozzle; a side arm moveably disposed within the bay, wherein the side arm is positioned at an end of the slider, the end of the slider comprising a groove aligned with the side arm, wherein the groove extends from an outer edge of the slider into an interior portion of the slider, wherein the groove is angled to receive the side arm as the slider moves.

Abstract: IOL injectors and associated methods are described. An IOL injector may include a collapsible portion configured to reduce the length of the IOL injector when the collapsible portion is altered from an uncollapsed configuration to a collapsed configuration. In some instances, an IOL may be advanced from a storage location to a dwell location when the collapsible portion is altered from the uncollapsed configuration to the collapsed configuration. An IOL injector may include one or more of a hydraulic damper and a ribbed damper.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. Embodiments include removing a substantially cylindrical cap from an inserter to expose a substantially cylindrical sleeve, removing a cover from a substantially cylindrical container holding sensor components, and fitting the sensor components into the inserter.

Abstract: Certain aspects of the present disclosure provide an apparatus and method of using a multifunctional device to cut/tab a graft from a donor region of an eye. The apparatus includes a multifunctional device for ophthalmic surgery, having an insertion sleeve comprising an inner surface defining a compartment, a flat wire contained within the compartment folded to form a loop, wherein the flat wire comprises a sharp edge (continuous or tabbed) operable for cutting retinal tissue, and wherein the loop is positioned at a distal end of the insertion sleeve, and a handpiece coupled to the insertion tube and configured to adjust a size of the loop.

Abstract: An injector for intraocular lenses has a housing and a plunger movable within the housing. An elastomeric sleeve is sized and shaped to fit around a portion of the plunger, providing damping friction opposing the movement of the plunger. The sleeve is sterile and disposable, allowing a new sleeve to be used for each procedure.

Abstract: A trolling motor has a steering motor transmitting torque to a steering shaft, which is coupled to a lower propulsion unit such that rotation of the steering shaft rotates the propulsion unit about a steering axis. A controller is in signal communication with the steering motor. A foot pedal in signal communication with the controller has a foot pad pivotable about a pivot axis and sends electrical steering signals to the controller (and thus steering motor) in response to pivoting of the foot pad. A variable resistance device is coupled to the foot pedal and controllable to vary resistance to pivoting of the foot pad about the pivot axis based on a position, velocity, acceleration, and/or jerk of the steering shaft. Additionally or alternatively, the variable resistance device provides haptic feedback to a user via the foot pad to inform the user about information related to the trolling motor system.

Abstract: A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

Abstract: Intraocular lens (IOL) injectors are describe that include a rack and pinion to advance an IOL through the IOL injector and eject the IOL therefrom. IOL injectors described herein may also include a slide advance operable to advance an IOL from a storage location to a dwell location within the IOL injector.

Abstract: A device for mechanically assisting with scleral depression is disclosed. A top ring and a bottom ring are rotationally engaged where the bottom ring is capable of attachment to an eyelid speculum, and is thus fixed while in use. A variable vertical displacement apparatus is attached to the top ring. A rod and depressing member are engaged with the variable vertical displacement apparatus such that the depressing member is capable of both vertical and horizontal travel around the periphery of a patient's eye, allowing a surgeon to depress the sclera of a patient's eye while at the same time performing a surgical procedure.

Abstract: The invention relates to glaucoma pump implant (100) developed for use in reducing intra ocular pressure of glaucoma patients. The invention particularly relates to a glaucoma pump implant (100) that allows the glaucoma pump implant (100) to act as an active pump by utilizing diameter changes of pupil (210) and iris (220) caused by light variations.

Abstract: Intraocular lens injectors described herein may include a symmetrical arranged storage compartment, nozzle passage, and plunger tip in order to symmetrically fold and provide symmetrical loading to an intraocular lens during advancement and delivery so as to avoid rotation of the intraocular lens about longitudinal, vertical, and/or lateral axes during advancement and/or delivery of the intraocular lens.

Abstract: An IOL injector including a plunger having a spring-assisted IOL delivery mechanism is described.

Abstract: An injector of intracorneal segments has a disposable segment holding head comprising a lancet (36) formed with a housing closed by the lid (37) wherein a sterilized corneal segment (11) is housed, behind which there is a needle (26) longitudinally slidable under the action of a trigger (31) and a spring (32). The head also has a manual selector (38) to deflect the needle to place the segment at 90° of the head to the right or left of a channel made in the cornea for injection. The segment pre-installed in the head is provided with recesses formed by knurling (16) on its outer chord (14) where it couples to the needle for the push.

Abstract: Intraocular lens loading devices and methods of use. In some embodiment the devices are used to sequentially splay first and second haptics while loading the intraocular lens into a delivery lumen.