Abstract: A lancing device having a housing with a proximal end, a distal end and a longitudinal axis. The lancing device also has a lancet carrier translationally supported with respect to the housing. The lancet carrier has a proximal end and a distal end. The lancing device additionally has a charging mechanism and/or an ejection mechanism adapted to pivot into the lancing device for engaging portions of the lancet carrier to perform the same.

Abstract: A tail pressing type disposable safety lancet includes a shell, a lancet core, a spring and tail cover. The shell has an elastic arm for locking the lancet core, wherein: the tail cover has an active locking part for locking and the elastic arm has a passive locking part for locking correspondingly; the positions, the fitting time of the active locking part and the passive locking part correlate with the active and passive unlocking parts; when the tail cover is pressed during use, it forces the lancet core to unlock for ejection and puncturing, and the tail cover and elastic arm enter the locking state and cannot be used again. After use of the safety lancet, the tail cover permanently locks on the elastic arm of the shell, ensuring the safety of single use, and the user visually recognizes the tail cover is retracted at the tail of the shell.

Abstract: A lancing device with rear adjustment of penetration depth includes a cap, cap holder, ejection pin and shell, wherein: the lancing device has an external and medium depth adjusting sleeve. The ejection pin is located in the medium sleeve and the external depth adjusting sleeve is sleeved outside the medium sleeve; the external sleeve connects axially and circumferentially to the shell, and a rotary locating mechanism is between the external sleeve and the shell; the medium sleeve is connected circumferentially and axially in a sliding way, and a rotary moving mechanism is between the medium the external sleeve, and the medium includes a passive impact face relative to the active impact face of the ejection pin; the external sleeve includes a manual adjusting ring outside the lancing device at the middle and rear part, and rotates to drive the medium sleeve to move axially, changing the needle tip penetration depth.

Abstract: A biological fluid collection device that includes a housing and a cartridge that is removably receivable within a portion of the housing is disclosed. The biological fluid collection device of the present disclosure allows for collection of capillary blood from a finger stick and provides a closed system that reduces the exposure of a blood sample. In one embodiment, a cartridge of the present disclosure also provides fast mixing of a blood sample with a sample stabilizer. In another embodiment, a cartridge of the present disclosure provides automatic plasma separation of the blood sample. Advantageously, once the cartridge is filled with a sample aid removed from the housing, the cartridge can be used for a variety of important purposes.

Abstract: Applicators for applying an on-skin assembly to skin of a host and methods of their use and/or manufacture are provided. An applicator includes an insertion assembly configured to insert at least a portion of the on-skin assembly into the skin of the host, a housing configured to house the insertion assembly, the housing comprising an aperture through which the on-skin assembly can pass, an actuation member configured to, upon activation, cause the insertion assembly to insert at least the portion of the on-skin assembly into the skin of the host, and a sealing element configured to provide a sterile barrier and a vapor barrier between an internal environment of the housing and an external environment of the housing.

Abstract: The disclosed apparatus, systems and methods relate to devices, systems and methods for the collection of bodily fluids involving a single-use actuation and retraction mechanism disposed within a collector.

Abstract: An actuation device includes a lancing device held by and moveable relative to a distal end portion of a housing. A drive member is supported by the housing and arranged to engage the lancing device to move the lancing device in the first direction from a retracted position to an extended position upon movement of the drive member in a first direction. A piercing member of the lancing device is arranged to extend from the distal end portion of the housing by a first distance when the lancing device is moved to the extended position, the first distance being adjustable by adjusting the retracted position of the lancing device relative to the distal end portion of the housing.

Abstract: An injector for introducing a capsular tension ring and intended for once-only use, and a method for manufacturing such an injector. The injector includes: a housing extending in longitudinal direction of the injector, and a throughfeed channel. A plunger is arranged movably in the channel and includes an engaging means for engaging the capsular tension ring, and further includes a guide element on a guide arm. A spring mechanism co-acts with the plunger and is configured to displace the plunger from a starting state, in which the engaging means engages the capsular tension ring, to an activating state in which the capsular tension ring is carried inward into the throughfeed channel. The housing has a guide with first and second channel parts, and a wall part for carrying the guide element from the first to the second channel part, and the first channel part is provided with a resistance threshold.

Abstract: A needle guard grip device may include a body extending from a first end to a second end along a central longitudinal axis of the body. The body may include a plurality of ribs extending perpendicularly to the central longitudinal axis. The plurality of ribs may include a first set of longitudinally spaced ribs disposed on a first side of the central longitudinal axis, and a second set of longitudinally spaced ribs disposed on a second side of the central longitudinal axis that is opposite of the first side. Moving along the central longitudinal axis, ribs of the first set of longitudinally spaced ribs may alternate with ribs of the second set of longitudinally spaced ribs.

Abstract: Various collection devices, systems and methods relating to the use of devices with open microfluidic channels disposed within a housing defining a lumen. These devices make use of microneedles passed through apertures to induce fluid flow into microfluidic channel networks for collection and analysis. The device can be actuated via button when placed on the skin of a patient to collect a fluid sample, such as a blood draw.

Abstract: A test cartridge includes an adjustable lancet. The adjustable lancet is controlled by a controller. The adjustable lancet automatically detects a subject's finger, adjusts the lancet's height, pricks the finger to draw blood, moves a tube to collect the blood, moves the tube away from the finger, and empties the blood from the tube into a vial or receptacle. The adjustable lancet may include safety features to prevent the lancet to trigger when the subject's fingernail is facing the lancet, to control the amount that the lancet pierces the subject's finger, and/or to prevent the reuse of a test cartridge for multiple persons or multiple times by the same person. The adjustable lancet may include a massager wheel and/or a pressure bar to rub the subject's finger after the finger is pierced to facilitate drawing of the blood from the finger.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: A medical instrument having an aspiration and/or injection needle and handle device. The handle device provides audible and/or tactile feedback during the application of activation forces, thus enabling the user to determine where the distal end of the aspiration and/or injection needle is relative to a sheath. More than two grooves are present on a shaft of an activation handle of the handle device. An O-ring resides within a handle portion of the handle device. The O-ring seats and unseats within the grooves based on the amount of applied force.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: This specimen collection device has a channel through which a specimen can be drawn by capillarity. The channel has two channel sections that extend from the tip side to the base side and are connected at the tip side. One of the channel sections is connected to a base side specimen intake port, and the other terminates at a location prior to reaching the base end. An air hole is provided at this terminating location. The specimen collection device is equipped with an extraction unit for collecting a prescribed amount of the specimen. The extraction unit includes the two channel sections on the tip side of the air hole, and can be severed from the other sections of the device body of the specimen collection device via a severable section.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: A lancing device having improved charging features is disclosed. In one example embodiment, the charging mechanism generally includes a user actuated portion or charging member and a cam feature for engagement therewith. The charging member includes a finger projection or boss and the cam feature includes a ramped surface. Actuating the charging member causes the finger projection to movably engage the ramp surface of the cam feature and charge the drive mechanism.

Abstract: A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial integrity/organizational architecture thereof. The transfer device can include a controller, an actuator assembly, a plunger, and a needle. The controller can move the transfer device and the plunger independently.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices.

Abstract: A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.

Abstract: Provided is a liquid medicine injection device having a needle holder slid immediately by using the elasticity of a spring such that a needle installed at the needle holder may be instantly inserted into a patient.

Abstract: A disposable blood-taking needle with double-surface cap includes a lancet body with a needle tip, a lancet handle and a lancet cap. The lancet body is fixed inside the lancet handle and the needle tip extends out of the first end of the lancet handle to be inserted into the lancet cap. The body of the lancet cap is a block structure, which includes a first face and a second face. Both the first face and second face are flat and opposed such that when one face faces upwards, the other face faces downwards and the included angle between them in space is less than 45°; the first face is provided with a first blind hole and the second face is provided with a second blind hole and both the first blind hole and the second blind hole match the first end of the lancet handle in respect of connection relationship. In the block structure, except the first face and the second face, the other external surfaces are arcuate faces protruding outward and/or angular faces protruding outward.

Abstract: An apparatus for obtaining and analyzing a blood sample is presented. The apparatus comprises an integrated drive unit having a common drive source and a drive force transmission gearing that couples a lancet drive, a device for advancing a magazine, and a sample transfer device to the drive source. A tensioning rotor and a drive rotor are mounted so that they are rotatable coaxially to one another. A first cam control converts the rotation of the drive rotor into a radial forward and reverse movement of a drive rod. A second cam control converts the rotational movement of the tensioning rotor into a linear movement of a link slide. A switching link moved by the link slide rotates the magazine an additional step. A third cam control converts the rotational movement of the tensioning rotor into a linear movement of a pressure tappet perpendicular to the piercing axis.

Abstract: A puncturing system has a carrier tape carrying multiple lancets, a device housing comprising a conveying facility for moving the lancets into a usage position consecutively by moving the carrier tape in a conveying direction, a puncturing drive for accelerating one of the lancets that is positioned in the usage position in a puncturing motion, an opening in the device housing for touching against a body part in which a puncture is to be made by the puncturing motion of one of the lancets, an actuation facility for driving the conveying facility, and an unlockable interlock comprising a stop that blocks further transport of the carrier tape as soon as one of the lancets has reached the usage position.

Abstract: Surgical instruments and methods including a stop guard are described herein. An exemplary instrument can include an inner shaft disposed within an outer shaft, the inner shaft including a tissue-piercing tip and being effective to secure an end effector to the device. A stop guard can be coupled to the inner shaft and extend through outer shaft sidewall openings when the tip is advanced distally or retract into the outer shaft when the tip is retracted proximally. In a percutaneous procedure, external force applied to the stop guard by the tissue can retract the tip to prevent damage to surrounding tissue as the instrument is advanced distally. Moreover, once passed through pierced tissue, the stop guard can be redeployed when the inner shaft is advanced distally to secure an end effector to the instrument and can prevent inadvertent withdrawal of the instrument.

Abstract: The present invention provides a surgically invasive pointed article for skin penetration and capillary whole blood extraction whose penetration ability can be disabled after use by deforming the tips. The present invention is made by injection molding a plastic needle 35 having an anchoring means 45 using a first material, followed by another injection molding process to over-mold a first body segment 20 and second body segment 30 using a second material to encase the plastic needle 35 thereby anchoring the plastic needle 35 to prevent further movement of the plastic needle 35. The encasing of the second material provide a barrier isolating the plastic needle 35 from the ambient to protect the tips 50 from damage and once sterilized, to conserve the sterile conditions till point of use. The barrier formed by a second over-molding process comprises a detachable cap 20 and a body 30.

Abstract: A fluid infusion device is provided with a cannula spring which functions as an introducer needle, a retraction return spring, and a fluid path. A hollow cannula tubing is wound, bent and sharpened into a shape which allows it to operate as an introducer needle, retraction spring and fluid path in an infusion device. A button is used to insert the introducer needle portion of the cannula spring and a soft catheter, and once the introducer needle portion and catheter have been fully inserted, an engagement between the button and post of the base of the infusion device releases the cannula spring such that the introducer needle portion of the cannula spring automatically retracts, leaving the catheter in the body. An end of the introducer needle portion of the cannula spring remains in fluid communication with the catheter in the body to provide an uninterrupted fluid path.

Abstract: A single-use compression lancing device includes a bottom housing, a top housing, and a lancet. The lancet is generally configured for selective interengagement and guidance within the bottom and top housings. The top housing is configured for slidingly engaging the bottom housing such that manipulation of the top housing relative to the bottom housing causes a sharp tip portion of the lancet to protrude from an opening of the top housing. In one form, at least one arm extending from the lancet interengages a portion of the top housing such that the lancet is retracted within a portion of the bottom housing.

Abstract: In some embodiments, the present invention generally relates to the separation of blood within a device to form plasma or serum. In some embodiments, the present invention generally relates to the removal of fluids, such as blood, contained within a device. In one aspect, the present invention is generally directed to systems and methods for receiving blood from a subject and processing the blood to form plasma or serum. For example, a device may be applied to the skin of a subject to receive blood from the subject and pass the blood through a separation membrane, which separates the blood into plasma and a portion concentrated in blood cells. As another example, blood or plasma may be allowed to clot within the device and serum (the unclotted portion of the blood) may be withdrawn from the device. The device may contain, in some cases, a vacuum source such as a pre-packaged vacuum to facilitate receiving of blood and/or passage of the blood through the separation membrane to produce plasma or serum.

Abstract: A lancing device includes a housing, a lancet carrier translational within the housing, a drive spring for propelling the lancet carrier through a translational lancing stroke, and a charging mechanism. The charging mechanism includes a first cam member that is rotatable relative to the housing, a second cam member that abuts the first cam member, is coupled to the lancet carrier, and is restricted from rotation relative to the housing, and a rotatable handle co-rotationally attached to the first cam member. Rotation of the handle rotates the first cam member with it, causing the first cam member to rotate against the second cam member, which in response traverses axially because it is restricted from rotation, thereby retracting the lancet carrier to a retracted or charged state.

Abstract: A sensor module is disclosed herein. The sensor module includes a main housing defining an analysis zone within the housing. The sensor module also includes a skin piercing member mounted within the main housing. The skin piercing member is movable relative to the main housing between a retracted position and an extended position. The main housing of the sensor module defines a fluid sample flow passage that extends from a sampling end of the main housing to the analysis zone. The fluid sample flow passage includes a funnel structure through which the skin piecing member extends when in the extended position. The fluid sample flow passage also includes capillary flow enhancing slots that extend outwardly from opposite sides of the funnel structure.

Abstract: The invention relates to a lancing device (1) for taking blood samples, comprising a housing (2), an axially displaceable lancet holder element (32) for holding a lancet (12), and a display apparatus (40) for displaying the respective operating states (41,42) of the lancing device (1), the display apparatus (40) comprising a release element (13) for initiating a lancing procedure, in which the axially displaceable lancet holder element (32) is accelerated in a lancing direction (18), in which, when the lancing device (1) is in an operating state (41) ready for lancing, the release element (13) is arranged in a disengaged display position (43) projecting further outwards over the outer housing surface (15) than when the lancing device (1) is in a different operating state (42).

Abstract: A protecting mechanism for a blood sampling device contains: a trigger unit and a switching assembly. The trigger unit includes a lancet holder, a triggering shaft, and a resilient element. The lancet holder has a launching portion, a first outer protrusion, a through orifice, and a first inner shoulder, wherein a bottom end of the triggering shaft moves in the through hole, and the triggering shaft has a first outer shoulder for engaging with the first inner shoulder of lancet holder, the resilient element is fitted with the triggering shaft and abuts against the lancet holder by ways of its bottom end. The switching assembly includes a fixing jacket having an abutting portion, a rotating tube having a first inner protrusion and two opposite second inner protrusions, and a driving sheath having two stopping sets, wherein each stopping set has two second outer protrusions.

Abstract: A meter configured to perform a blood analysis is presented where the meter has a housing, the housing having an aperture configured to receive a body part of a user. The meter also having a plurality of light sources supported by the housing and a controller configured to control the plurality of light sources to indicate an operational status of the apparatus.

Abstract: A device for use in imaging a liquid sample comprises an inlet for accepting the sample, a connection conduit and a detection chamber for detection of the sample, preferably optical detection of the sample. The connection conduit connects the inlet to the detection chamber and contains one or more dry reagents for reaction with the sample as the sample passes through the connection conduit. Specific embodiments include devices arranged for treating a blood sample, in particular lysing and staining the sample. The liquid flow may be driven by capillary effect. The device may further include liquid handling structures arranged for centrifugally driven liquid flow, for example to meter a volume of sample and separate the sample into phases by centrifugation.

Abstract: A lancet magazine for use in a lancing aid is described comprising a plurality of lancets each having a lancet body at the proximal end of the lancet and a lancet tip at the distal end of the lancet, where the proximal end of the lancet points in the direction of the proximal end of the housing of the lancet magazine and the distal end of the lancet is aligned in the direction of the distal end of the housing and the lancets in the unused state are completely surrounded by the housing. Furthermore, an extension unit is movably connected to the housing in such a manner that the housing can be extended by movement of the extension unit in the direction of the distal end of the housing such that the lancet is prevented from emerging from the lancet magazine.

Abstract: A lancet device generally includes a housing having opposing lateral sides extending between a forward end and a rearward end, and a shield coaxially and movably associated with the housing. The housing includes a plurality of longitudinal ribs extending along a portion of at least one of the opposing lateral sides. The plurality of longitudinal ribs form a finger grip on at least one of, and typically both of the opposing lateral sides. The shield is generally movable from a first position in which the shield extends outwardly from the forward end of the housing to a second position in which the shield is at least partially moved within the housing, based on axial pressure applied by the user against the finger grip formed by the longitudinal ribs.

Abstract: An applicator device including a housing, an impactor for impacting a microneedle array and accelerating the microneedle array toward the target site, wherein the impactor is capable of moving along an arcuate path to move the microneedle array toward the target site. Also, an applicator device including a housing, a patch applicator pivotally supported by the housing, and a torsion spring. The patch applicator has a retaining portion and a patch contacting portion, and the patch contacting portion is capable of moving along a substantially arcuate path between a first position and a second position. The torsion spring is capable of biasing the patch applicator relative to the housing.

Abstract: A sample collection device for a fluid includes: a substantially disk-shaped body having a periphery; a capillary channel extending through the body and bounded by the periphery, having a first end and a second end, wherein the first end is adapted to draw the fluid into the channel by capillary action; a sample collection well located in the vicinity of the second end and in fluid communication with the capillary channel; and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the major surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge having a housing comprising an air vent in fluid communication with the capillary channel when the disk is rotated in a first position.

Abstract: A one-time/single use safety lancet system includes a body; a spring coupled to the body; a keeper having a deformable member; and a core for supporting a lancet and having an end coupled to the spring. The core further has a first latch for engaging the deformable member when the lancet system is in an armed state. The deformable member of the keeper is fractured after one use of the lancet system which prevents any subsequent arming of the lancet system. The keeper may be made part of the lancet body. The core may include a second latch, wherein the second latch permanently deforms or fractures the deformable member of the keeper after the single, one-time arming of the safety lancet system.

Abstract: A medicament injection device includes a device body portion that includes a penetrating member channel. A penetrating member is provided with a sharpened distal tip and shaft portion that is slidably disposed within the penetrating channel to provide for a penetrating to travel in a linear axial movement. A pierceable membrane isolates a penetrating member in an associated penetrating member chamber. A medicament reservoir is in fluid communication with the penetrating member. The medicament reservoir is configured to house a medicament and is coupled to the penetrating member to allow for delivery of medicament to a tissue site.

Abstract: In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a biological fluid sample. The analyte sensor has a base including a top and bottom side, a lid, and an attachment member including one or more retention tabs coupled proximate the top side so that the analyte sensor can be grasped by the sensor's top side. Manufacturing methods and systems adapted to use and dispense the analyte sensors are provided, as are numerous other aspects.

Abstract: A lancing actuator (114) includes a drive element (118) for driving a lancing element, the drive element being guided within a housing (112), a combined compression and torsion element (120) which, by a relaxing movement thereof, is adapted to drive the lancing motion, a combined triggering and driving device (122) having an actuating element (124) and a locking device (126), wherein the actuating element has an initial state and an actuated state and is accessible from the outside of the housing, wherein, in the initial state, the drive element is locked in the locking device under a torsional stress exerted by the combined compression and torsion element, wherein the combined triggering and driving device is configured in a manner that, when the actuating element makes a movement along an actuation path from the initial state into the actuated state, a torque is exerted on the drive element which prevails over the torsional stress exerted by the combined compression and torsion element such that the drive e

Abstract: A puncture needle cartridge (1) includes: a lancet body (5) mounted with a puncture needle (3) on a front end side and having a mount (4) on a rear end side; and a plate-like first case (6) and second case (7) covering the lancet body (5) from above and below and arranged slidably back and forth along each other. The puncture needle cartridge (1) is configured such that the first case (6) is slid forward of the second case (7), and in this slid state, the first case (6) and the second case (7) are secured to each other when ejected from the puncture instrument (10). This can make the puncture needle cartridge (1) impossible to mount again on the puncture instrument (10).

Abstract: A lancer device that enables a user to draw blood from a patient and discard the used lancet without touching it. The device also has an adjustable tip for selecting the depth of stylet penetration into the patient and a triggering mechanism that utilizes a yoke latch and a leaf spring to discharge the lancet. The lancer also has a dampening feature to reduce vibrations when the lancet is moving.

Abstract: A lancing device includes a housing (10, 12) and a lancet holder movably mounted within the housing. The lancet holder has a forward portion defining a socket (30) for partially surrounding and retaining in use the rear portion of a lancet. A lancet release element (40, 42) can be moved forward to cooperate with lugs on the socket to expand it to allow insertion and/or removal of the lancet with minimal insertion or withdrawal force.

Abstract: An advancement mechanism of a lancing device operates to sequentially advance lancets in a cartridge. The advancement mechanism includes a rotary drive gear assembly with a first gear and a second gear that co-rotate in a first angular direction by operation of an inter-gear unidirectional drive mechanism such as a ratcheting mechanism. A second-gear unidirectional lock mechanism, such as a ratcheting mechanism, locks the second drive gear from co-rotating with the first drive gear in a second opposite angular direction without impeding rotation in the first direction. The second gear directly or indirectly rotationally drives a pinion gear, which rotationally drives a cartridge gear to advance the lancets in indexed increments for use. The first drive gear is rotated in the first and second directions by a rack gear of a translating operating handle. In addition, a rotary-gear cap-displacement mechanism and a rotary-gear charging/actuation mechanism are provided in other embodiments.

Abstract: The invention relates to a lancet, which has a lancet tip at a front end and which on an upper face comprises a contact surface for placing a test element thereon and at least one channel for receiving a sample, wherein an upwardly open section of the channel runs in the contact surface. According to the invention, the channel has another upwardly open channel section which runs on the upper face of the lancet in or adjacent to a surface area that is lower than the contact surface, wherein the contact surface is arranged between the lancet tip and the lower surface area. The invention further relates to a system comprising such a lancet and a test element, and to a method for transferring a liquid sample from a channel of a lancet which is designed as a groove or slot to a test element.