Lancet Patents (Class 606/181)
  • Patent number: 10524708
    Abstract: A disposable blood-taking needle with double-surface cap includes a lancet body with a needle tip, a lancet handle and a lancet cap. The lancet body is fixed inside the lancet handle and the needle tip extends out of the first end of the lancet handle to be inserted into the lancet cap. The body of the lancet cap is a block structure, which includes a first face and a second face. Both the first face and second face are flat and opposed such that when one face faces upwards, the other face faces downwards and the included angle between them in space is less than 45°; the first face is provided with a first blind hole and the second face is provided with a second blind hole and both the first blind hole and the second blind hole match the first end of the lancet handle in respect of connection relationship. In the block structure, except the first face and the second face, the other external surfaces are arcuate faces protruding outward and/or angular faces protruding outward.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: January 7, 2020
    Inventor: Guoping Shi
  • Patent number: 10456070
    Abstract: An apparatus for obtaining and analyzing a blood sample is presented. The apparatus comprises an integrated drive unit having a common drive source and a drive force transmission gearing that couples a lancet drive, a device for advancing a magazine, and a sample transfer device to the drive source. A tensioning rotor and a drive rotor are mounted so that they are rotatable coaxially to one another. A first cam control converts the rotation of the drive rotor into a radial forward and reverse movement of a drive rod. A second cam control converts the rotational movement of the tensioning rotor into a linear movement of a link slide. A switching link moved by the link slide rotates the magazine an additional step. A third cam control converts the rotational movement of the tensioning rotor into a linear movement of a pressure tappet perpendicular to the piercing axis.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: October 29, 2019
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Hans List, Kai Fluegge
  • Patent number: 10357193
    Abstract: A puncturing system has a carrier tape carrying multiple lancets, a device housing comprising a conveying facility for moving the lancets into a usage position consecutively by moving the carrier tape in a conveying direction, a puncturing drive for accelerating one of the lancets that is positioned in the usage position in a puncturing motion, an opening in the device housing for touching against a body part in which a puncture is to be made by the puncturing motion of one of the lancets, an actuation facility for driving the conveying facility, and an unlockable interlock comprising a stop that blocks further transport of the carrier tape as soon as one of the lancets has reached the usage position.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: July 23, 2019
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Ahmet Konya, Hans-Juergen Kuhr, Frank Deck, Hans List, Michael Keil, Christian Hoerauf, Thomas Weiss, Marcus Schlothauer
  • Patent number: 10335196
    Abstract: Surgical instruments and methods including a stop guard are described herein. An exemplary instrument can include an inner shaft disposed within an outer shaft, the inner shaft including a tissue-piercing tip and being effective to secure an end effector to the device. A stop guard can be coupled to the inner shaft and extend through outer shaft sidewall openings when the tip is advanced distally or retract into the outer shaft when the tip is retracted proximally. In a percutaneous procedure, external force applied to the stop guard by the tissue can retract the tip to prevent damage to surrounding tissue as the instrument is advanced distally. Moreover, once passed through pierced tissue, the stop guard can be redeployed when the inner shaft is advanced distally to secure an end effector to the instrument and can prevent inadvertent withdrawal of the instrument.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: July 2, 2019
    Assignee: Ethicon LLC
    Inventors: Christopher J. Hess, Frederick E. Shelton, IV, Monica L. Zeckel, Jeffrey L. Savage
  • Patent number: 10271781
    Abstract: The present invention provides a surgically invasive pointed article for skin penetration and capillary whole blood extraction whose penetration ability can be disabled after use by deforming the tips. The present invention is made by injection molding a plastic needle 35 having an anchoring means 45 using a first material, followed by another injection molding process to over-mold a first body segment 20 and second body segment 30 using a second material to encase the plastic needle 35 thereby anchoring the plastic needle 35 to prevent further movement of the plastic needle 35. The encasing of the second material provide a barrier isolating the plastic needle 35 from the ambient to protect the tips 50 from damage and once sterilized, to conserve the sterile conditions till point of use. The barrier formed by a second over-molding process comprises a detachable cap 20 and a body 30.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: April 30, 2019
    Inventor: Chee Yen Lim
  • Patent number: 10265466
    Abstract: A fluid infusion device is provided with a cannula spring which functions as an introducer needle, a retraction return spring, and a fluid path. A hollow cannula tubing is wound, bent and sharpened into a shape which allows it to operate as an introducer needle, retraction spring and fluid path in an infusion device. A button is used to insert the introducer needle portion of the cannula spring and a soft catheter, and once the introducer needle portion and catheter have been fully inserted, an engagement between the button and post of the base of the infusion device releases the cannula spring such that the introducer needle portion of the cannula spring automatically retracts, leaving the catheter in the body. An end of the introducer needle portion of the cannula spring remains in fluid communication with the catheter in the body to provide an uninterrupted fluid path.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: April 23, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Russell Cole, Michael Creighton, Alyssa Jackson, Arthur Klotz
  • Patent number: 10244974
    Abstract: A single-use compression lancing device includes a bottom housing, a top housing, and a lancet. The lancet is generally configured for selective interengagement and guidance within the bottom and top housings. The top housing is configured for slidingly engaging the bottom housing such that manipulation of the top housing relative to the bottom housing causes a sharp tip portion of the lancet to protrude from an opening of the top housing. In one form, at least one arm extending from the lancet interengages a portion of the top housing such that the lancet is retracted within a portion of the bottom housing.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: April 2, 2019
    Inventor: Amit Garg
  • Patent number: 10188335
    Abstract: In some embodiments, the present invention generally relates to the separation of blood within a device to form plasma or serum. In some embodiments, the present invention generally relates to the removal of fluids, such as blood, contained within a device. In one aspect, the present invention is generally directed to systems and methods for receiving blood from a subject and processing the blood to form plasma or serum. For example, a device may be applied to the skin of a subject to receive blood from the subject and pass the blood through a separation membrane, which separates the blood into plasma and a portion concentrated in blood cells. As another example, blood or plasma may be allowed to clot within the device and serum (the unclotted portion of the blood) may be withdrawn from the device. The device may contain, in some cases, a vacuum source such as a pre-packaged vacuum to facilitate receiving of blood and/or passage of the blood through the separation membrane to produce plasma or serum.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: January 29, 2019
    Assignee: Seventh Sense Biosystems, Inc.
    Inventors: Ramin Haghgooie, Donald E. Chickering, III, Shawn Davis, Mark Michelman, Howard Bernstein, Kristin Horton
  • Patent number: 10105086
    Abstract: A lancing device includes a housing, a lancet carrier translational within the housing, a drive spring for propelling the lancet carrier through a translational lancing stroke, and a charging mechanism. The charging mechanism includes a first cam member that is rotatable relative to the housing, a second cam member that abuts the first cam member, is coupled to the lancet carrier, and is restricted from rotation relative to the housing, and a rotatable handle co-rotationally attached to the first cam member. Rotation of the handle rotates the first cam member with it, causing the first cam member to rotate against the second cam member, which in response traverses axially because it is restricted from rotation, thereby retracting the lancet carrier to a retracted or charged state.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: October 23, 2018
    Inventors: James M. Christopher, Lauren R. Pusey, Jeremy Rodgers
  • Patent number: 10034629
    Abstract: A sensor module is disclosed herein. The sensor module includes a main housing defining an analysis zone within the housing. The sensor module also includes a skin piercing member mounted within the main housing. The skin piercing member is movable relative to the main housing between a retracted position and an extended position. The main housing of the sensor module defines a fluid sample flow passage that extends from a sampling end of the main housing to the analysis zone. The fluid sample flow passage includes a funnel structure through which the skin piecing member extends when in the extended position. The fluid sample flow passage also includes capillary flow enhancing slots that extend outwardly from opposite sides of the funnel structure.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: July 31, 2018
    Inventors: James L. Say, Stephen L. Pohl
  • Patent number: 10010283
    Abstract: The invention relates to a lancing device (1) for taking blood samples, comprising a housing (2), an axially displaceable lancet holder element (32) for holding a lancet (12), and a display apparatus (40) for displaying the respective operating states (41,42) of the lancing device (1), the display apparatus (40) comprising a release element (13) for initiating a lancing procedure, in which the axially displaceable lancet holder element (32) is accelerated in a lancing direction (18), in which, when the lancing device (1) is in an operating state (41) ready for lancing, the release element (13) is arranged in a disengaged display position (43) projecting further outwards over the outer housing surface (15) than when the lancing device (1) is in a different operating state (42).
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: July 3, 2018
    Assignee: Gerresheimer Regensburg GMBH
    Inventors: Julia Volkmuth, Andreas Eder
  • Patent number: 10004443
    Abstract: A protecting mechanism for a blood sampling device contains: a trigger unit and a switching assembly. The trigger unit includes a lancet holder, a triggering shaft, and a resilient element. The lancet holder has a launching portion, a first outer protrusion, a through orifice, and a first inner shoulder, wherein a bottom end of the triggering shaft moves in the through hole, and the triggering shaft has a first outer shoulder for engaging with the first inner shoulder of lancet holder, the resilient element is fitted with the triggering shaft and abuts against the lancet holder by ways of its bottom end. The switching assembly includes a fixing jacket having an abutting portion, a rotating tube having a first inner protrusion and two opposite second inner protrusions, and a driving sheath having two stopping sets, wherein each stopping set has two second outer protrusions.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: June 26, 2018
    Inventor: Shao-Lun Hsiao
  • Patent number: 9939403
    Abstract: A meter configured to perform a blood analysis is presented where the meter has a housing, the housing having an aperture configured to receive a body part of a user. The meter also having a plurality of light sources supported by the housing and a controller configured to control the plurality of light sources to indicate an operational status of the apparatus.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: April 10, 2018
    Inventors: Frank Richter, Ross MacArthur, Elizabeth Verity Wolseley-Hext, Joseph David Cowan, Lee Thomas Smith, David John Mills
  • Patent number: 9914120
    Abstract: A device for use in imaging a liquid sample comprises an inlet for accepting the sample, a connection conduit and a detection chamber for detection of the sample, preferably optical detection of the sample. The connection conduit connects the inlet to the detection chamber and contains one or more dry reagents for reaction with the sample as the sample passes through the connection conduit. Specific embodiments include devices arranged for treating a blood sample, in particular lysing and staining the sample. The liquid flow may be driven by capillary effect. The device may further include liquid handling structures arranged for centrifugally driven liquid flow, for example to meter a volume of sample and separate the sample into phases by centrifugation.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 13, 2018
    Assignee: Biosurfit S.A.
    Inventors: João Manuel De Oliveira Garcia Da Fonseca, Ricardo Cabeça
  • Patent number: 9895093
    Abstract: A lancet magazine for use in a lancing aid is described comprising a plurality of lancets each having a lancet body at the proximal end of the lancet and a lancet tip at the distal end of the lancet, where the proximal end of the lancet points in the direction of the proximal end of the housing of the lancet magazine and the distal end of the lancet is aligned in the direction of the distal end of the housing and the lancets in the unused state are completely surrounded by the housing. Furthermore, an extension unit is movably connected to the housing in such a manner that the housing can be extended by movement of the extension unit in the direction of the distal end of the housing such that the lancet is prevented from emerging from the lancet magazine.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: February 20, 2018
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Richard Forster, Susanne Gentsch, Andreas Gorshoefer, Michael Keil, Thomas Weiss, Robert Wessel
  • Patent number: 9844330
    Abstract: A lancet device generally includes a housing having opposing lateral sides extending between a forward end and a rearward end, and a shield coaxially and movably associated with the housing. The housing includes a plurality of longitudinal ribs extending along a portion of at least one of the opposing lateral sides. The plurality of longitudinal ribs form a finger grip on at least one of, and typically both of the opposing lateral sides. The shield is generally movable from a first position in which the shield extends outwardly from the forward end of the housing to a second position in which the shield is at least partially moved within the housing, based on axial pressure applied by the user against the finger grip formed by the longitudinal ribs.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: December 19, 2017
    Assignee: Becton, Dickinson and Company
    Inventor: Bradley M. Wilkinson
  • Patent number: 9789249
    Abstract: An applicator device including a housing, an impactor for impacting a microneedle array and accelerating the microneedle array toward the target site, wherein the impactor is capable of moving along an arcuate path to move the microneedle array toward the target site. Also, an applicator device including a housing, a patch applicator pivotally supported by the housing, and a torsion spring. The patch applicator has a retaining portion and a patch contacting portion, and the patch contacting portion is capable of moving along a substantially arcuate path between a first position and a second position. The torsion spring is capable of biasing the patch applicator relative to the housing.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: October 17, 2017
    Inventors: Franklyn L. Frederickson, Michael D. Johnson
  • Patent number: 9743873
    Abstract: A sample collection device for a fluid includes: a substantially disk-shaped body having a periphery; a capillary channel extending through the body and bounded by the periphery, having a first end and a second end, wherein the first end is adapted to draw the fluid into the channel by capillary action; a sample collection well located in the vicinity of the second end and in fluid communication with the capillary channel; and an axis of rotation extending through the center of the disk and which is substantially perpendicular to the major surface of the disk-shaped body. In a preferred embodiment, the sample collection device is adapted to rotate about the axis of rotation within a cartridge having a housing comprising an air vent in fluid communication with the capillary channel when the disk is rotated in a first position.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 29, 2017
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventors: Kory A. Gunnerson, Raymond F. Jakubowicz, Andrew M. Kirsch, James Ellis Robinson, Daniel P. Salotto, David A. Tomasso, Zhong Ding, William Franklin Gottermeier, Aaron Michael Swick
  • Patent number: 9730626
    Abstract: A one-time/single use safety lancet system includes a body; a spring coupled to the body; a keeper having a deformable member; and a core for supporting a lancet and having an end coupled to the spring. The core further has a first latch for engaging the deformable member when the lancet system is in an armed state. The deformable member of the keeper is fractured after one use of the lancet system which prevents any subsequent arming of the lancet system. The keeper may be made part of the lancet body. The core may include a second latch, wherein the second latch permanently deforms or fractures the deformable member of the keeper after the single, one-time arming of the safety lancet system.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: August 15, 2017
    Assignee: INTRINSYK, LLC
    Inventors: Paul Robert Fuller, James Keith Booker, Thomas Ralph Gannon
  • Patent number: 9694144
    Abstract: A medicament injection device includes a device body portion that includes a penetrating member channel. A penetrating member is provided with a sharpened distal tip and shaft portion that is slidably disposed within the penetrating channel to provide for a penetrating to travel in a linear axial movement. A pierceable membrane isolates a penetrating member in an associated penetrating member chamber. A medicament reservoir is in fluid communication with the penetrating member. The medicament reservoir is configured to house a medicament and is coupled to the penetrating member to allow for delivery of medicament to a tissue site.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: July 4, 2017
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Dominique M. Freeman
  • Patent number: 9678034
    Abstract: In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a biological fluid sample. The analyte sensor has a base including a top and bottom side, a lid, and an attachment member including one or more retention tabs coupled proximate the top side so that the analyte sensor can be grasped by the sensor's top side. Manufacturing methods and systems adapted to use and dispense the analyte sensors are provided, as are numerous other aspects.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: June 13, 2017
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventor: Steven C. Charlton
  • Patent number: 9662046
    Abstract: A lancing actuator (114) includes a drive element (118) for driving a lancing element, the drive element being guided within a housing (112), a combined compression and torsion element (120) which, by a relaxing movement thereof, is adapted to drive the lancing motion, a combined triggering and driving device (122) having an actuating element (124) and a locking device (126), wherein the actuating element has an initial state and an actuated state and is accessible from the outside of the housing, wherein, in the initial state, the drive element is locked in the locking device under a torsional stress exerted by the combined compression and torsion element, wherein the combined triggering and driving device is configured in a manner that, when the actuating element makes a movement along an actuation path from the initial state into the actuated state, a torque is exerted on the drive element which prevails over the torsional stress exerted by the combined compression and torsion element such that the drive e
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: May 30, 2017
    Inventor: Ahmet Konya
  • Patent number: 9649060
    Abstract: A puncture needle cartridge (1) includes: a lancet body (5) mounted with a puncture needle (3) on a front end side and having a mount (4) on a rear end side; and a plate-like first case (6) and second case (7) covering the lancet body (5) from above and below and arranged slidably back and forth along each other. The puncture needle cartridge (1) is configured such that the first case (6) is slid forward of the second case (7), and in this slid state, the first case (6) and the second case (7) are secured to each other when ejected from the puncture instrument (10). This can make the puncture needle cartridge (1) impossible to mount again on the puncture instrument (10).
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: May 16, 2017
    Assignee: Panasonic Healthcare Holdings Co., Ltd.
    Inventor: Akio Nagao
  • Patent number: 9622697
    Abstract: A lancer device that enables a user to draw blood from a patient and discard the used lancet without touching it. The device also has an adjustable tip for selecting the depth of stylet penetration into the patient and a triggering mechanism that utilizes a yoke latch and a leaf spring to discharge the lancet. The lancer also has a dampening feature to reduce vibrations when the lancet is moving.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: April 18, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Todd M. Chelak, Jonathan B. Gabel, Robert E. West
  • Patent number: 9603563
    Abstract: A lancing device includes a housing (10, 12) and a lancet holder movably mounted within the housing. The lancet holder has a forward portion defining a socket (30) for partially surrounding and retaining in use the rear portion of a lancet. A lancet release element (40, 42) can be moved forward to cooperate with lugs on the socket to expand it to allow insertion and/or removal of the lancet with minimal insertion or withdrawal force.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: March 28, 2017
    Inventors: Christopher Hudson, Timothy Muller
  • Patent number: 9517027
    Abstract: An advancement mechanism of a lancing device operates to sequentially advance lancets in a cartridge. The advancement mechanism includes a rotary drive gear assembly with a first gear and a second gear that co-rotate in a first angular direction by operation of an inter-gear unidirectional drive mechanism such as a ratcheting mechanism. A second-gear unidirectional lock mechanism, such as a ratcheting mechanism, locks the second drive gear from co-rotating with the first drive gear in a second opposite angular direction without impeding rotation in the first direction. The second gear directly or indirectly rotationally drives a pinion gear, which rotationally drives a cartridge gear to advance the lancets in indexed increments for use. The first drive gear is rotated in the first and second directions by a rack gear of a translating operating handle. In addition, a rotary-gear cap-displacement mechanism and a rotary-gear charging/actuation mechanism are provided in other embodiments.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: December 13, 2016
    Inventors: Gil Kan, Brian M. Collins, Gregory Lamps
  • Patent number: 9480427
    Abstract: The invention relates to a lancet, which has a lancet tip at a front end and which on an upper face comprises a contact surface for placing a test element thereon and at least one channel for receiving a sample, wherein an upwardly open section of the channel runs in the contact surface. According to the invention, the channel has another upwardly open channel section which runs on the upper face of the lancet in or adjacent to a surface area that is lower than the contact surface, wherein the contact surface is arranged between the lancet tip and the lower surface area. The invention further relates to a system comprising such a lancet and a test element, and to a method for transferring a liquid sample from a channel of a lancet which is designed as a groove or slot to a test element.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: November 1, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Joachim Hoenes, Hans List
  • Patent number: 9456782
    Abstract: The invention relates to a system for withdrawing body fluid from a body part via a withdrawal site located on the surface of the body part, with at least one sensor for detecting at least one variable dependent on the location or state of the withdrawal site, and with an evaluation unit for evaluating the at least one variable detected by the at least one sensor and for triggering a reaction, dependent on the value of the detected variable, in the system for withdrawing body fluid, said reaction serving to prepare the system for puncturing the surface of the body part, and with at least one puncturing device for creating an opening in the body at the withdrawal site. The invention further relates to an integrated analysis system, to a method for configuring a system for withdrawal of body fluid, and to a method for selecting a menu item from a menu for controlling a system for withdrawing body fluid from a body part.
    Type: Grant
    Filed: October 13, 2011
    Date of Patent: October 4, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Jürgen Rasch-Menges, Günter Schmelzeisen-Redeker, Jochen Schulat, Wilfried Schmid, Rudolf Pachl
  • Patent number: 9445761
    Abstract: A lancing device includes an advance-and-eject mechanism with a positioning member for manipulating a series of interconnected lancets. The advance-and-eject mechanism includes an actuator, a control channel, a cam-and-follower mechanism, one or more axial-contact members, and one or more angular-contact members. Actuating the actuator relative to the control channel imparts rotational and axial forces on the positioning member, and the cam-and-follower mechanism selectively restricts rotational and/or axial motion of the positioning member to induce first-stage rotation, second-stage translation, third-stage rotation, and fourth-stage translation.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: September 20, 2016
    Inventors: Benjamin L. Klein, Lauren R. Pusey
  • Patent number: 9414774
    Abstract: A system and method for carrying out the withdrawal of body fluid with as little body fluid as possible visible to the user at the end of the process. The present invention provides a pressure piece for exerting pressure on a body part. The pressure piece is moved relative to a support for the body part, and in the final phase of fluid withdrawal, the compressive or resistive force of the pressure piece on the body part is reduced in order to avoid the escape of body fluid from the puncture site. The support results in a defined positioning of the body part that rests against it for the lancing process, whereas the relative movement of the pressure piece enables an additional increase in pressure and thus an improved collection of fluid.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: August 16, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Stephan Korner, Rainer Jaeggi, Patrick Griss, Emad Sarofim, Irio Guiseppe Calasso
  • Patent number: 9380974
    Abstract: An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: July 5, 2016
    Assignee: Intuity Medical, Inc.
    Inventors: Craig M. Litherland, Jeffrey L. Emery, Raul Escutia, James W. Pfeiffer, Jeffrey M. Jones
  • Patent number: 9351678
    Abstract: A lancet holder includes a holder body having a lancet seat at one end to mount a lancet and receiving the lancet and elastic fixing portions arranged in pairs to face each other on the inner side of the holder body so that the lancet received in the holder body is vertically held, and elastically fixing the lancet.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: May 31, 2016
    Assignee: I-SEN, INC.
    Inventors: Geun Sig Cha, Hakhyun Nam, Eun-Jong Cha, Kyung-Ah Kim
  • Patent number: 9312095
    Abstract: A method and system is provided for automatically preparing transmission electron microscopy (TEM) samples for examination by depositing extremely small samples onto a grid without need for a blotting step. A sample liquid droplet is formed at the end of a capillary, wherein a portion of the liquid is transferred to the TEM sample grid by contact. The excess volume in the liquid droplet is then retracted by an adjacent capillary. After a predetermined time interval, the retraction capillary is moved toward the drop of the sample to remove the excess volume. As compared to a conventional machine, where the blotting procedure can deform the structure of the molecule of interest, the present invention utilizes a very low shear rate for removal of the excess sample fluid.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: April 12, 2016
    Inventors: Anubhav Tripathi, Jinkee Lee, Arjit Bose
  • Patent number: 9301715
    Abstract: A method for producing an analytical magazine is proposed. The analytical magazine is designed to receive a plurality of analytical aids in a plurality of chambers. The method comprises the following steps: providing at least one first component of the analytical magazine, wherein the first component comprises a plurality of receptacles; providing a plurality of analytical aids, wherein the analytical aids are connected to one another and preferably oriented with respect to one another by at least one holding element; introducing the analytical aids into the receptacles; and separating the analytical aids from the holding element.
    Type: Grant
    Filed: August 18, 2011
    Date of Patent: April 5, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Hans List, Uwe Krämer, Wilhelm Leichner
  • Patent number: 9301775
    Abstract: A fingernail drill has a drill bit and a tip which is capable of drilling through a thickness of a fingernail. The tip extends longitudinally outwards from an abutment integrally formed with the drill bit, and the drill cannot drill past the abutment. The distance from the abutment to a distal end of the tip is such that the drill can drill through the thickness of the fingernail but cannot damage tissue under the fingernail. A kit is provided that includes the fingernail drill and a dispenser for dispensing a substance through a hole drilled by the fingernail drill.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: April 5, 2016
    Inventor: Moshe Dolev
  • Patent number: 9247900
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: February 2, 2016
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, James R. Petisce, Kum Ming Woo, Sean Saint, John Nolting
  • Patent number: 9237904
    Abstract: A puncturing instrument includes a cylindrical main body case having a puncture aperture on a lower end side; a needle holder provided on a puncture aperture side inside the cylindrical main body case; a first elastic object for moving the needle holder to the puncture aperture side; and a second elastic object for pulling the needle holder back to an upper end side inside the cylindrical main body case, from a state in which the needle holder is moved to the puncture aperture side by the first elastic object. A rotator rotates around a rotation shaft fixed to the cylindrical main body case, and is coupled with a coupling portion of the needle holder on a first one of two sides of the rotator with the rotation shaft interposed therebetween and is coupled with the second elastic object on a second one of the two sides of the rotator.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: January 19, 2016
    Inventors: Takumi Shima, Akio Nagao
  • Patent number: 9186099
    Abstract: A lancet cartridge is provided with a skin contact section that is held in the interior of a lancet holder and that includes a second pricking opening. A first pricking opening is formed to a size such that a skin contact section can be accommodated therein. Upon pressing in the pricking direction, the skin contact section is accommodated in the first pricking opening, and the leading end section of a pricking member protrudes through the second pricking opening.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: November 17, 2015
    Assignee: ARKRAY, Inc.
    Inventors: Masahiro Fukuzawa, Susumu Nishino
  • Patent number: 9182326
    Abstract: The invention relates to a device and a method for filtering a liquid sample, wherein first capillary-driven filtration occurs and, after initial filling, pressure-operated filtration is performed by applying a vacuum or a positive pressure.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: November 10, 2015
    Assignee: Boehringer Ingelheim Microparts GmbH
    Inventors: Dirk Kurowski, Dirk Osterloh, Ying Yu
  • Patent number: 9179867
    Abstract: Lancet device includes a housing, a removable front cap mounted to the housing, a lancet holding member, and a trigger. A system is utilized for placing the lancet device in a trigger-set or armed position. A depth adjustment system includes a member that is at least partially rotatably mounted and that has an axis of rotation arranged substantially perpendicular to a center axis of the lancet holding member. An ejection system is utilized for at least one of preventing axial movement of the lancet holding member and removing or ejecting a lancet from the lancet holding member.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: November 10, 2015
    Inventors: Steven Schraga, Brian Schwartz, Paul R. Fuller
  • Patent number: 9173599
    Abstract: There is provided a lancet comprising a lancet body, a lancet cap and a pricking component. In the lancet, the lancet body and the lancet cap are made of resin and the pricking component is made of metal. The pricking component is situated in both of the lancet body and the lancet cap, and the tip of the pricking component is covered with the lancet cap. The lancet body of the lancet is thin except for a rim portion of the body, and the rim portion of the lancet body has such a form that the rim portion extends symmetrically from the thinned portion of the lancet body.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: November 3, 2015
    Inventor: Hideaki Saeki
  • Patent number: 9138185
    Abstract: A lancet assembly includes a lancet, a lancet engaging part, and a lancet case housing the lancet and the lancet engaging part. In the lancet assembly of the present invention, the lancet engaging part and the lancet cap are disposed such that they are capable of making contact with each other. When the lancet engaging part is forced to move forward with respect to the lancet in a pricking direction, the lancet cap is pressed by the lancet engaging part, and thereby the bridging component is broken so that the lancet cap is separated from the lancet body. When the lancet engaging part is forced to further move forward, the separated lancet cap moves to the position off a pricking pathway of the pricking component within the lancet case.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: September 22, 2015
    Inventors: Hideaki Saeki, Hirokazu Imori, Kazuharu Seki
  • Patent number: 9125975
    Abstract: A storage assembly is removably connectable to a drug delivery device. A first chamber is disposed in the housing. A plurality of penetrating members are stored in the first chamber. A second chamber is disposed in the housing for storing the plurality of penetrating members after being used in an injection. A transfer drum disposed in the housing transfers one of the penetrating members from the first chamber to an injection position and from the injection position to the second chamber following an injection.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: September 8, 2015
    Assignee: Becton, Dickinson and Company
    Inventors: Gary Searle, Charles Hwang
  • Patent number: 9066699
    Abstract: A lancing device includes a housing (10, 12) for receiving in use a replaceable lancet (34) introduced into said housing, a drive (58, 59) actuable to drive the lancet momentarily to project its tip from the housing, and a nose portion (14) having an aperture through which said lancet projects when fired. The nose portion is threadedly engaged (78, 81) with the forward end (10) of the housing to allow the penetration depth of said lancet tip to be pre-set, and is resiliently deformable between a position in which it is locked against rotation and a position in which it is free to rotate.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: June 30, 2015
    Inventors: Clive Nicholls, Robert Michael Wozencroft
  • Patent number: 9066698
    Abstract: A tube assembly, system and method for biological sample collection. In one embodiment, the tube assembly of the present disclosure includes a first tube, a second tube, a mechanism for securing the first and second tubes. The securing mechanism orients the first ends of the first and second tubes in a manner such that the first end of the second tube extends beyond the first end of the first tube to create an interstitial space between the outer diameter of the first tube and the inner diameter of the second tube.
    Type: Grant
    Filed: October 11, 2011
    Date of Patent: June 30, 2015
    Assignee: Bioanalytical Systems Inc.
    Inventors: Scott R. Peters, James M. Hampsch
  • Patent number: 9060723
    Abstract: An arrangement for producing a sample of body fluid from an opening created in a skin surface at a sampling site including a cartridge with a plurality of compartments and a plurality of sampling sites, and a detector assembly. Each sampling site includes a skin-penetration member having a first end configured to pierce the surface of the skin and an inner lumen in communication with the first end, a spring actuator operatively associated with the skin-penetration member, and a needle hub connecting the skin-penetration member and the spring actuator. The needle hub includes a reagent pad and the spring actuator is configured to drive the skin-penetration member to form the wound opening. Each compartment at least partially encloses the skin-penetration member, the spring actuator, and the needle hub of a respective sampling site.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: June 23, 2015
    Assignee: Intuity Medical, Inc.
    Inventors: Raul Escutia, Jeffrey L. Emery, Craig M. Litherland
  • Publication number: 20150142037
    Abstract: A puncture needle cartridge (2) comprises: a columnar lancet body (6) having a puncture needle on the front end side and a puncture instrument mount (5) on the rear end side; a protective cap (13) covering the puncture needle and having a shape extending toward the front end; a skin contact part (10) placed in front of the tip of the puncture needle, having a planar shape perpendicular to the puncture needle, and formed with a through hole to put the protective cap (13) through; an elongate plate-like extension (9) extending from the skin contact part (10) toward the rear end; and an elastic object (8) for coupling the extension (9) to the lancet body (6) and making the tip of the puncture needle be biased to be located in the rear end side behind the skin contact part (10).
    Type: Application
    Filed: April 5, 2013
    Publication date: May 21, 2015
    Inventor: Akio Nagao
  • Patent number: 9033898
    Abstract: Systems and methods for delivering and/or receiving a substance or substances, such as blood, from subjects. In one embodiment, devices and methods for receiving blood from a subject employ devices including a substance transfer component (such as one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In certain embodiments, substances may be received from and/or delivered to the subject with relatively little pain. The pain may be assessed, for example, using pain scales such as the WONG BAKER FACES Pain Scale. The device may be self-contained, applied to the skin, and activated to receive blood from the subject. The device, or a portion thereof, may be processed to determine the blood and/or an analyte within the blood using sensors or agents in the device or an external apparatus.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: May 19, 2015
    Assignee: Seventh Sense Biosystems, Inc.
    Inventors: Donald E. Chickering, III, Howard Bernstein, Shawn Davis, Ramin Haghgooie, Douglas A. Levinson, Mark Michelman, Ping Gong
  • Patent number: 9023292
    Abstract: Disclosed herein is a device for sampling blood by capillarity for separating a plasma phase of the blood from the cell phase. The device is a strip and includes a filter having a membrane with no clumping agents, a prefilter for spreading blood over the surface of the membrane; and an absorbent paper downstream from the filter. The membrane is dimensioned to cover only a part of the surface of the prefilter and the migration of blood by capillarity within the prefilter takes place essentially lengthwise relative to the strip before blood comes into contact with the membrane.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: May 5, 2015
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Hervé Rostaing, Christine Peponnet, Patrick Pouteau, Elodie Sollier
  • Patent number: 9017356
    Abstract: A lancet device includes a housing, a trigger, a system for placing the lancet device in a trigger-set or armed position, and a multi-lancet unit comprising a plurality of lancets arranged one in front of the other and positioned in the housing. Each lancet includes a front end, a needle which extends from the front end, and a rear end. The front end of at least one of the plurality lancets is removably connected to the rear end of another of the plurality of lancets. A method of puncturing a surface of skin using the lancet device includes arranging the lancet device adjacent against a user's skin and triggering the lancet device so that one of the plurality of lancet is caused to penetrate the user's skin.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: April 28, 2015
    Assignee: Stat Medical Devices, Inc.
    Inventors: Steven Schraga, Paul R. Fuller, Brian Schwartz, David A. Carhart