Inserted In Vascular System Patents (Class 606/194)
  • Patent number: 10799375
    Abstract: An aortic bare stent and an aortic dissection stent are disclosed. The aortic bare stent is in a tubular net structure, with multiple support stents in circles and arranged along an axial direction. Two adjacent support stents are connected by a connector stent. The connector stent is made of a hyper-elastic material. A flexural rigidity of the connector stent is less than that of the support stent. The support stent is made of a single-strand hyper-elastic nickel titanium wire or formed by cutting a nickel titanium tubing. The connector stent is made of a multi-strand composite wire. The multi-strand composite wire is formed by twisting or weaving multiple strands of filaments, and each strand of filament is independently of a nickel titanium material.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: October 13, 2020
    Assignee: HANGZHOU WEIQIANG MEDICAL TECHNOLOGY CO., LTD.
    Inventors: Yongsheng Wang, Weiguo Fu, Jianmin Li, Tingchao Zhang
  • Patent number: 10779971
    Abstract: A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: September 22, 2020
    Assignee: Intact Vascular, Inc.
    Inventors: Robert Giasolli, Peter Schneider
  • Patent number: 10779975
    Abstract: A stent device delivery system and method of making. The stent device delivery system includes a stent device, an outer sheath overlaying the stent device in a radially compact, delivery configuration of the stent device, and a pull member. The outer sheath may include a first layer and a reinforcement layer that are laminated together, a portion of the pull member captured radially between the first layer and the reinforcement layer. At least a partial length of the captured portion of the pull member may be formed with a varying radial profile.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: September 22, 2020
    Assignee: C. R. Bard, Inc.
    Inventors: Jurgen Dorn, Markus Forster, Daniel Dietrich, Alexander Maurer, Erhard Elsässer
  • Patent number: 10758715
    Abstract: Systems and methods and devices are provided for arresting or reversing the effects of myocardial remodeling and degeneration after cardiac injury, without the potential drawbacks associated with previously existing systems and methods, by at least partially occluding flow through the superior vena cava over multiple cardiac cycles, and more preferably, by adjusting the interval or degree of occlusion responsive to a sensed level of patient activity. In some embodiments, a controller is provided that actuates a drive mechanism responsive to a sensed level of patient activity to provide at least partial occlusion of the patient's superior vena cava, while a data transfer circuit of the controller provides bi-directional transfer of physiologic data to the patient's smartphone or tablet to permit display and review of such data.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: September 1, 2020
    Assignee: Tufts Medical Center, Inc.
    Inventors: Navin K. Kapur, Richard H. Karas
  • Patent number: 10743857
    Abstract: A tissue wall of a biological lumen may be reinforced by embedding a material or structure into the tissue wall. The reinforcement material or structure may embed by application of outwardly directed force along an interior side of the tissue wall, threading, or injection. The reinforcement material or structure may act as an embedded scaffold that limits expansion or contraction of the tissue wall to pushing or pulling forces. An anchor device, such as a medical device, may anchor to the reinforced portion of the tissue wall.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: August 18, 2020
    Assignee: Endobetes, Inc.
    Inventors: Marc Bessler, Ryan Hanlon, Zachary Tyler Melanson
  • Patent number: 10743977
    Abstract: Disclosed is a novel filter and delivery means. The device described within will not interfere with standard practice and tools used during standard surgical procedures and tools such as cannulas, clamps or dissection instruments including valve replacement sizing gages or other surgical procedures where the patient must be put on a heart-lung machine cross-clamping the aorta.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: August 18, 2020
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Randall T. Lashinski
  • Patent number: 10709542
    Abstract: A stent with an improved anti-slip function. The stent includes: a cylindrical stent including a plurality of openings formed by weaving wires, and a plurality of peaks, the cylindrical stent being subjected to heat treatment, wherein the cylindrical stent has a PTFE-first artificial blood vessel layer being in entire contact with an inner surface thereof, and a plurality of PTFE-second artificial blood vessel layers being in partial contact with an outer surface thereof, and the first and second artificial blood vessel layers are heat-fused together to encompass the cylindrical stent, thereby forming a plurality of first sections having a plurality of openings obstructed and a plurality of seconds sections having the plurality of openings remaining unobstructed, wherein the first sections are inserted into a lesion while pressing against the lesion, thereby being caught in the lesion, and the second sections are caught in the lesion meshed with the openings.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: July 14, 2020
    Assignees: TAEWOONG MEDICAL CO., LTD.
    Inventors: Kyong Min Shin, Sung Wook Park, Dong Su Ko
  • Patent number: 10709877
    Abstract: Catheter assemblies and methods for making and using catheter assemblies are disclosed. An example a catheter assembly includes a catheter shaft and a balloon attached to the catheter shaft. The balloon includes a body and a proximal waist portion. The proximal waist portion has a proximal end. The catheter assembly also has a fiber braid including one or more individual filaments disposed along the balloon. The fiber braid has a proximal end aligned with the proximal end of the waist portion. The catheter assembly also has a polymer sleeve disposed on the catheter shaft, wherein in the polymer sleeve abuts the proximal end of the balloon waist and the proximal end of the braid.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: July 14, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Daniel Lee Krautkremer, Katherine M. Prindle
  • Patent number: 10709875
    Abstract: An introducer sheath (10) comprises a tubular body (11) with a distal portion (12) and a proximal portion (13), the proximal portion (13) being configured to be inserted into the patient's body. Introducer sheath can be separated along its length in a longitudinal direction. The introducer sheath (10) further comprises at least a first handle (15) which is pivotable about a fulcrum (21). The first handle (15) has a first end portion (151) and a free second end portion (152) so as to form a lever, such that pivoting the handle (15) about the fulcrum (21) causes a contacting portion (23) of the handle to act on a respective counter portion (24) that is operatively connected to the distal portion (12) of the tubular body (11). This creates a breaking force that causes the distal portion (12) of the tubular body (11) to break.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: July 14, 2020
    Assignee: ABIOMED EUROPE GMBH
    Inventors: Ger O'Carrol, Thorsten Siess, Walid Aboulhosn
  • Patent number: 10695174
    Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: June 30, 2020
    Assignee: Surmodics, Inc.
    Inventors: Bruce M. Jelle, Joram Slager, Joseph S. McGonigle, Rick Murphy, Andrew G. Bach, Teryl L. Woodwick Sides, Ambereen Angamuthu, Sean Lundquist, Gary Opperman, Nathan A. Lockwood
  • Patent number: 10695159
    Abstract: A method of capturing and removing a thrombus from a large vein is performed using a percutaneous thrombectomy device. The thrombectomy device includes a delivery sheath, a filter body, and an inner catheter provided with an agitation member. The sheath is advanced until a distal end is positioned proximal to the thrombus. The filter body is deployed distal to the sheath and proximal to the thrombus. The filter body preferably has a funnel shape with a tapered proximal end portion and an open distal end. The inner catheter is advanced through the sheath for contacting the thrombus with the agitation member. The agitation member is actuated to disrupt the thrombus. Thrombus particles are captured using the filter body and negative pressure is preferably applied through the sheath. The method is well-suited for treating deep vein thrombosis and does not require the use of thrombolytic drugs.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: June 30, 2020
    Inventor: David L. Hauser
  • Patent number: 10695206
    Abstract: Catheter systems and methods for deployment of an endoluminal prosthesis in a body lumen of a patient while maintaining control of a position of the endoluminal prosthesis during the deployment process. Some of the systems and methods are configured to minimize frictional forces of components of the catheter systems during deployment procedures.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: June 30, 2020
    Assignee: TRIVASCULAR, INC.
    Inventors: Diego Aristizabal, Dale L Ehnes, Teresa Woodson
  • Patent number: 10682448
    Abstract: A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: June 16, 2020
    Assignee: Aria CV, Inc.
    Inventors: Karl Vollmers, John Scandurra
  • Patent number: 10682492
    Abstract: A medical device that is configured to house an expandable balloon includes a tubular sheath and a retaining member. The tubular sheath includes a longitudinal slit that extends parallel to a longitudinal axis of the tubular sheath and the retaining member is configured to retain the tubular sheath in a closed configuration. The tubular sheath may house the expandable balloon while the expandable balloon is attached to a catheter that is configured to navigate the expandable balloon into a body of a patient. The tubular sheath may be configured to house the expandable balloon substantially through the process of inserting the expandable balloon into the vasculature of the patient. Once the expandable balloon has been introduced into the introducer sheath and/or inserted into the vasculature of the patient, the retaining member may be disengaged and the tubular sheath removed from the catheter.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: June 16, 2020
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Alan Connors, Shyam Nagasrinivasa, Emily Schoenhoff, Janet Komatsu
  • Patent number: 10682220
    Abstract: An example medical device is disclosed as an expandable stent. The stent includes a tubular scaffold having an inner surface, an outer surface, and a lumen extending therein. The expandable stent also includes a liner disposed within the lumen of the tubular scaffold. Further, the liner is radially spaced from a medial region of the tubular scaffold to define a tissue ingrowth region along an uncovered portion of the medial region. Additionally, the liner extending along the tissue ingrowth region is configured to limit the amount of tissue ingrowth along the medial region of the scaffold.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: June 16, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Martyn G. Folan, Thomas M. Keating, Jacques Deviere, Nicolas Cauche
  • Patent number: 10667906
    Abstract: A system for expanding a device in a conduit or orifice of a human body includes a balloon member that is movable from a first configuration to a second configuration. External surfaces of the balloon member can collectively have a non-cylindrical cross-section relative to a main axis of the balloon member, such that the external surfaces of the balloon member generally conform to the anatomical shape of the conduit or orifice when the balloon member is in the second configuration.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: June 2, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark Chau, Travis Zenyo Oba, Tammy Huntley, Qinggang Zeng, August R. Yambao, Rafael Pintor
  • Patent number: 10660771
    Abstract: A system for delivering a surgical staple can include various components. The system may include an elongate body with a proximal end, a distal end, and a plurality of delivery platforms disposed adjacent the distal end. A sheath can move relative to the elongate body from a first position in which the distal end of the sheath is disposed distally of a distal-most distal delivery platform to a second position in which the distal end of the sheath is disposed proximally of at least one delivery platform. A plurality of intravascular tacks can be within the system with each disposed about a corresponding delivery platform.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: May 26, 2020
    Assignee: Intact Vacsular, Inc.
    Inventors: Robert Giasolli, Peter Schneider
  • Patent number: 10646364
    Abstract: An angioplasty apparatus for facilitating accurate placement of a lumen stent for dilating a stenosis, the apparatus includes arcuate low pressure balloon segment(s) connected at a distal end of a guiding catheter with gap(s) to facilitate blood flow during a stenting procedure. Optimal positioning of a stent at a lumen bifurcation is facilitated to obviate any tendency of a stent to miss a proximal end of a stenosis branch lumen while concomitantly preventing the stent from protruding into an original lumen, such as a patient's aorta.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: May 12, 2020
    Inventor: Nadar A. Dakak
  • Patent number: 10646362
    Abstract: The invention relates to a double stent comprising 2 coaxially arranged stents, wherein a first membrane is arranged between a first inner stent and a second outer stent and a second membrane is arranged on the second stent and wherein the membrane ends of the first and second membrane are brought together at the ends of the stents and are folded over onto the inside of the first stent and clamped under flexible tongues of the first stent.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: May 12, 2020
    Assignee: Bentley InnoMed GmbH
    Inventors: Rainer Bregulla, Milisav Obradovic
  • Patent number: 10632004
    Abstract: A stent is formed from a wire having an outer member, a radiopaque member lining at least a portion of the outer member inner surface, and a lumen defined by the outer member inner surface or the radiopaque member inner surface. A substance is disposed in the lumen to be eluted through at least one opening disposed through the outer member to the lumen. The radiopaque member may be substantially continuous along the length of the wire or disposed only along portions of the wire such as crowns. In a method for making the stent, a composite wire including an outer member, a radiopaque intermediate member, and a core member is shaped into a stent pattern and processed to remove the core member and optionally portions of the radiopaque intermediate member, without damaging the outer member.
    Type: Grant
    Filed: December 24, 2017
    Date of Patent: April 28, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventors: Ryan Bienvenu, James Mitchell, Dustin Thompson
  • Patent number: 10624768
    Abstract: A luminal stent includes a first tubular body and a second tubular body sleeved on the first tubular body, and at least one end of the second tubular body is sealingly connected to an outer surface of the first tubular body. In a radial support section of the luminal stent, the first tubular body includes at least one first radial support structure arranged in a circumferential direction thereof, and the second tubular body includes at least one second radial support structure arranged in a circumferential direction thereof and a coating film covering the second radial support structure. The second radial support structure has greater radial deformability than the first radial support structure. After implantation, the luminal stent can form a semi-closed gap between the first tubular body and the second tubular body or between the second tubular body and a lumen wall.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: April 21, 2020
    Assignee: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD
    Inventors: Benhao Xiao, Deyuan Zhang, Chang Shu, Yifei Wang
  • Patent number: 10619132
    Abstract: The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: April 14, 2020
    Assignee: Humacyte, Inc.
    Inventors: Shannon L. M. Dahl, Laura E. Niklason, Justin T. Strader, William E. Tente, Joseph J. Lundquist
  • Patent number: 10610347
    Abstract: A textile engineered prosthetic includes a continuous tube and at least one band of increased thickness formed over a portion of the continuous tube. The continuous tube includes a body portion and a bifurcated portion. The band of increased thickness forms a biomimetic surface. A bioreactor system includes a bioreactor container including a first compartment, a second compartment, a first membrane separating the first and second compartments, a third compartment, and a second membrane separating the second and third compartments. The bioreactor system also includes a woven textile prosthetic integrated with the bioreactor container in the second compartment to form a single bioreactor unit. A furcated textile article includes a continuous tube having a body portion and a furcated portion bifurcated N times from the body portion. The furcated textile article is a continuous woven piece formed from N shuttles of a shuttle loom, where N is at least two.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: April 7, 2020
    Assignee: THE SECANT GROUP, LLC
    Inventors: Eric H. Whiting, Seth A. Winner, Emily Y. Ho, Peter Gabriele, Jeremy J. Harris
  • Patent number: 10610390
    Abstract: An implant delivery system including a catheter having a delivery lumen; a pusher member slidably disposed in the catheter delivery lumen; a retaining member coupled to a distal end portion of the pusher member, the retaining member configured to retain an expandable implant in a collapsed configuration on the pusher member for delivery of the implant through the catheter delivery lumen; and an expandable actuator coupled to the distal end portion of the pusher member and operatively associated with the retaining member, wherein expansion of the actuator causes the retaining member to disengage from an implant carried on the pusher member, to thereby allow the implant to expand from the collapsed configuration.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: April 7, 2020
    Assignee: Stryker, Inc.
    Inventor: Michael Khenansho
  • Patent number: 10603195
    Abstract: This disclosure concerns medical devices, such as catheters and implantable devices, having radially adjustable features. More particularly, the catheters and implantable devices can radially expand and contract to perform various functions within the body. Expansion and contraction can be performed by a radially adjustable structure mounted on the medical device. For example, a medical device can include an body configured for in vivo introduction, a strip attached to the body and rolled into a ring such that layers of the strip radially overlap each other, and at least one motor actuatable by electrical energy to move the radially overlapping layers of the strip relative to one another and change a diameter of the ring and the body.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: March 31, 2020
    Inventor: Paul Sherburne
  • Patent number: 10583277
    Abstract: Balloon catheter and methods for making and using balloon catheters are disclosed. An example balloon catheter may include a proximal shaft. A midshaft may be attached to the proximal shaft. The midshaft may have an outer wall. A distal shaft may be attached to the midshaft. A balloon may be coupled to the distal shaft. An inflation lumen may be defined that extends from the proximal shaft, through the midshaft, and into the distal shaft. The inflation lumen may be in fluid communication with the balloon. A core wire may be disposed within the inflation lumen and may be attached to the midshaft.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: March 10, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Charles Rundquist, Eric Petersen, Jeffry Johnson, Roger W. McGowan, Chuanjing Xu, Adam D. Grovender
  • Patent number: 10568696
    Abstract: A method including generating a 3-D model of an unstenosed geometry of a blood vessel responsive to a 3-D model of an actual geometry of the blood vessel, establishing a parametric description of a stent that is expanded from a collapsed configuration to a final configuration that apposes the unstenosed geometry, developing a design for the stent by varying parameters of the parametric description responsive to a design heuristic that includes risk of stent strut breakage during a plastic deformation between the collapsed configuration and the final configuration, embodying the stent according to the design for the stent, inserting the stent into a blood vessel in its collapsed configuration, maneuvering the stent through the blood vessel to a stenosis, and expanding the stent to its final configuration.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: February 25, 2020
    Assignee: International Business Machines Corporation
    Inventors: Julia S. Baldauf, Darcy J. Beurle, Matthew Downton, Kerry J. Halupka, Stephen M. Moore, Christine Schieber
  • Patent number: 10562225
    Abstract: A system for manufacturing a synthetic organ suitable for transplantation into a biological organism is provided. This synthetic organ includes a three-dimensional polymer scaffold, wherein the shape and dimensions of the polymer scaffold are based on a native organ, wherein the polymer scaffold further includes at least one layer of polymer fibers that have been deposited by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both; and wherein the polymer scaffold has been preseeded with at least one type of biological cell prior to implantation into a biological organism, and wherein the at least one type of biological cell is operative to facilitate integration of the polymer scaffold into the organism so that the polymer scaffold may function in a manner significantly similar to or the same as the native organ.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: February 18, 2020
    Assignee: NANOFIBER SOLUTIONS, LLC
    Inventor: Jed K. Johnson
  • Patent number: 10561473
    Abstract: A catheter is provided with increased flexibility and radiopaque measurement visibility. The radiopaque measurement bands are formed of a continuous coil of radiopaque material defined by areas of tightly packed coils spaced by areas of loosely wound coils. Systems and methods of utilizing the measurement structure are also provided.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: February 18, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventors: Jeremy Stigall, Chris LeBlanc, Kazuo Sasamine
  • Patent number: 10561828
    Abstract: A treatment tool for an endoscope of the present invention includes a sheath, a balloon provided at the sheath and configured to be expandable to an inflated state from a reduced diameter state by injecting a fluid, a shaft member inserted through an inside of the balloon and configured to extend along a longitudinal axis of the sheath from a distal end of the balloon to a proximal end thereof, and an adhering portion provided on a side of an inner surface of a central portion of the balloon in a direction of the longitudinal axis, formed of an adhering material applied or adhered to the shaft member and configured to hold the central portion in a state in which the central portion is reduced in diameter.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: February 18, 2020
    Assignee: OLYMPUS CORPORATION
    Inventors: Koji Onishi, Masaru Yuasa, Koji Miyake, Norichika Fukushima, Shunsuke Miyauchi
  • Patent number: 10555738
    Abstract: Devices, systems, and methods used to seal a treatment area to prevent embolic agents from migrating are described. The concept has particular benefit in allowing liquid embolic to be used with a variety of intravascular therapeutic applications, including for occluding aneurysms and arteriovenous malformations in the neurovasculature.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: February 11, 2020
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Ivan Sepetka, Cathy Lei, Alejandro Berenstein, Monika Killer-Oberpfalzer, Heath Bowman
  • Patent number: 10548720
    Abstract: An implant system for treating glottic insufficiency includes an implant, which includes a balloon with a port connector or a catheter and a band comprising a proximate end attached to a portion of the balloon that translates away from the port connector or the catheter when the balloon is inflated through the port connector or the catheter.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: February 4, 2020
    Assignee: APREVENT MEDICAL INC.
    Inventors: Guan-Min Ho, Yenyu Chen, Chia-Yuan Chang
  • Patent number: 10548710
    Abstract: A tubular first device segment has longitudinally spaced proximal and distal first segment ends. The first device segment includes a first segment lumen. A tubular second device segment has longitudinally spaced proximal and distal second segment ends and a second segment lumen. A tubular eversion structure is located longitudinally intermediate the first and second device segments. The eversion structure has longitudinally spaced proximal and distal eversion ends separated by a tubular eversion structure wall. One of the proximal and distal eversion ends is attached to the first device segment and the other of the proximal and distal eversion ends is attached to the second device segment. At least a portion of the eversion structure wall is configured for selective intussusception into at least one of the first segment lumen, the second segment lumen, and another portion of the eversion structure wall.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: February 4, 2020
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Eric E. Roselli
  • Patent number: 10537379
    Abstract: The present invention relates to the field of medical treatment of diseases and disorders, as well as the field of biomedical engineering. Embodiments of the invention relate to the delivery of Irreversible Electroporation (IRE) through the vasculature of organs to treat tumors embedded deep within the tissue or organ, or to decellularize organs to produce a scaffold from existing animal tissue with the existing vasculature intact. In particular, methods of administering non-thermal irreversible electroporation (IRE) in vivo are provided for the treatment of tumors located in vascularized tissues and organs. Embodiments of the invention further provide scaffolds and tissues from natural sources created using IRE ex vivo to remove cellular debris, maximize recellularization potential, and minimize foreign body immune response. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 21, 2020
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Michael B. Sano, Rafael V. Davalos, John L. Robertson, Paulo A. Garcia, Robert E. Neal
  • Patent number: 10532191
    Abstract: A catheter includes a balloon that has an inner layer and an outer layer having elastic stretching properties, having tubular shapes, and being able to be inflated and deflated in response to a change of internal pressure; and a tubular net-shaped reinforcement member that is disposed between the inner layer and the outer layer such that at least a part thereof is movable with respect to the balloon. The reinforcement member has a first sleeve, and second sleeves which respectively surround both end portions of the first sleeve in an axial direction. A maximally inflated diameter of the second sleeve is set so as to be smaller than a maximally inflated diameter of the first sleeve.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: January 14, 2020
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Yasuhito Umeda, Naoyuki Maeda
  • Patent number: 10524809
    Abstract: The disclosure provides plaque treatment catheter assemblies for the treatment of arterial plaques and removal of clots. One assembly includes a second catheter tube movable within a first catheter tube, and an expansion member movable within the second tube. The second catheter tube has one or more distally-disposed and outwardly-expandable plaque treatment portion(s). Another assembly includes a catheter tube and at least one channel(s) within the catheter. The channel includes an elongate member with a distally-disposed plaque scoring or clot retrieval member. Optionally, the assembly includes an expandable member that can cause movement of the scoring member.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: January 7, 2020
    Assignee: Surmodics, Inc.
    Inventor: Charlie Olson
  • Patent number: 10517619
    Abstract: A medical device designed to be inserted into a lumen of a living body so as to block a flow of fluid in the lumen of the living body. The medical device includes: a long shaft part; an expandable part; and a covering part. The expandable part is an elastically deformable cylindrical body, and the cylindrical body having a proximal part connected to the shaft part. The covering part takes on a cylindrical shape and is flexible and deformable independently of the expandable part, and the cylindrical shape has a proximal part connected to a proximal part of the expandable part or connected to the shaft part located at a proximal side with respect to the expandable part. The covering part defines a space in the radial direction between a distal side end part of the cylindrical shape and the expandable part.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: December 31, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Masaomi Imai, Yuuki Masubuchi, Takashi Kitaoka, Takahiro Chida, Kazuaki Kanamoto
  • Patent number: 10517711
    Abstract: A dissection prosthesis system for implantation within a blood vessel includes a first prosthesis and a second prosthesis. The first prosthesis includes a first stent ring, a second stent ring, a first graft material band coupling the first stent ring to the second stent ring, a third stent ring, and a second graft material band coupling the second stent ring to the third stent ring. The second stent ring includes a plurality of openings that enable fluid flow from a lumen of the first prosthesis through the plurality of openings. The graft material bands may include band openings disposed therethrough to enable fluid flow from the lumen through the band openings. The second prosthesis includes a stent coupled to a graft material. The second prosthesis is configured to be disposed within the lumen of the first prosthesis.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: December 31, 2019
    Assignee: Medtronic Vascular, Inc.
    Inventor: Jeffery Argentine
  • Patent number: 10512556
    Abstract: A stent includes a high radial force segment and a highly flexible segment, where the diameters of the high radial force segment and the highly flexible segment are substantially the same. The stent may further be placed with an additional stent segment, where the additional stent segment has a radial force similar to the radial force of the highly flexible force segment.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: December 24, 2019
    Assignee: Vesper Medical, Inc.
    Inventors: Michael A. Longo, William James Harrison
  • Patent number: 10507123
    Abstract: A stent includes a first longitudinally extended cylinder having a C-shaped cross-section and a second longitudinally extended cylinder having a C-shaped cross-section. The first cylinder includes a plurality of first longitudinal struts and an array of first radial struts extending between the first longitudinal struts. The second cylinder includes a plurality of second longitudinal struts and an array of second radial struts extending between the second longitudinal struts. The first cylinder and the second cylinder are configured to form a dense mesh structure when assembled. When assembled, the second cylinder may be disposed in the first cylinder. The first cylinder may overlap with the second cylinder to form the dense mesh structure.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: December 17, 2019
    Assignee: MONARCH BIOSCIENCES, INC.
    Inventor: Vikas Gupta
  • Patent number: 10500035
    Abstract: A pancreatic stent includes a main body convertible between a compressed configuration for delivery and an expanded configuration once deployed, the main body including an inner surface defining a stent lumen and an outer surface. A plurality of drainage features are formed within the outer surface of the main body, the plurality of drainage features permitting placement of the pancreatic stent within a patient's pancreas without blocking side branches of the pancreas.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: December 10, 2019
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Kevin Walsh, Gary Trendel, Paul Mannion
  • Patent number: 10485685
    Abstract: A system for deploying an implantable medical device into a body lumen is disclosed. The system comprises a catheter having functional zones for stability, protection, flexibility, trackability and pushability. The system further comprises a device for deploying an implantable medical device with the catheter. A method for deploying an implantable medical device into a body lumen using the system is also disclosed.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: November 26, 2019
    Assignee: QUALIMED INNOVATIVE MEDIZINPRODUKTE GMBH
    Inventors: Eric K. Mangiardi, Martina Schmitt
  • Patent number: 10478194
    Abstract: An implant can include a frame and a mesh component coupled to the frame. The mesh component can define a first porosity, and the frame can define a frame porosity. The combined porosity of the mesh component and the frame can restrict blood flow into the implant.
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: November 19, 2019
    Assignee: Covidien LP
    Inventors: Richard Rhee, Earl Bardsley
  • Patent number: 10478201
    Abstract: The disclosure provides plaque treatment catheter assemblies for the treatment of arterial plaques and removal of clots. One assembly includes a second catheter tube movable within a first catheter tube, and an expansion member movable within the second tube. The second catheter tube has one or more distally-disposed and outwardly-expandable plaque treatment portion(s). Another assembly includes a catheter tube and at least one channel(s) within the catheter. The channel includes an elongate member with a distally-disposed plaque scoring or clot retrieval member. Optionally, the assembly includes an expandable member that can cause movement of the scoring member.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: November 19, 2019
    Assignee: Surmodics, Inc.
    Inventor: Charlie Olson
  • Patent number: 10470773
    Abstract: A vessel occluder used to occlude blood flow within the vasculature is described. The vessel occluder can include an expandable mesh portion having a flexible membrane that expands within a cavity of the expandable mesh portion. When expanded, the flexible membrane blocks blood passage through the mesh portion.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: November 12, 2019
    Assignee: Terumo Corporation
    Inventors: Shannon Maguire, Jessica Liang, Wendy Graczyk Beuthin, Tin Luong-Uhl, Peter Soliman
  • Patent number: 10441446
    Abstract: A prosthesis includes a first wire bent into a first waveform and spirally wrapped into a first helix having a plurality of windings that form a hollow cylindrical shape and a second wire bent into a second waveform and spirally wrapped into a second helix having a plurality of windings that form a hollow cylindrical shape. The first and second wires are disposed relative to each other such that the plurality of windings of the first wire and the plurality of windings of the second wire are disposed about a common longitudinal axis and the plurality of windings of the first wire and the plurality of windings of the second wire are axially offset from each other, with windings of the plurality of windings of the first wire alternating or interwoven between windings of the plurality of windings of the second wire along a length of the prosthesis.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: October 15, 2019
    Assignee: Medtronic Vascular, Inc.
    Inventors: Travis Rowe, Gustaf Belt
  • Patent number: 10420637
    Abstract: Apparatus and methods for stenting are provided comprising a stent attached to a porous biocompatible material that is permeable to endothelial cell ingrowth, but impermeable to release of emboli of predetermined size. Preferred stent designs are provided, as well as preferred manufacturing techniques. Apparatus and methods are also provided for use at a vessel branching. Moreover, embodiments of the present invention may comprise a coating configured for localized delivery of therapeutic agents. Embodiments of the present invention are expected to provide enhanced embolic protection, improved force distribution, and improved recrossability, while reducing a risk of restenosis and thrombus formation.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: September 24, 2019
    Assignee: Abbott Laboratories Vascular Enterprises Limited
    Inventors: Joost J. Fierens, Silvio R. Schaffner, Marc Gianotti, Gerd Seibold, Randolf von Oepen
  • Patent number: 10406325
    Abstract: An anchoring mechanism and method for anchoring a device within a biological conduit include an expandable element configured for retaining the device at a desired angle relative to a central axis of the biological conduit. A steering mechanism is preferably provided for orienting the device prior to operation of the anchoring mechanism. The anchoring mechanism and method are employed in drug delivery devices, brachytherapy devices or for anchoring a catheter or sheath to provide a working channel for reliable guidance of a wide range of tools to a target location within the body.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: September 10, 2019
    Assignee: COVIDIEN LP
    Inventor: Dorian Averbuch
  • Patent number: 10390977
    Abstract: A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: August 27, 2019
    Assignee: Intact Vascular, Inc.
    Inventors: Robert Giasolli, Peter Schneider
  • Patent number: 10391283
    Abstract: A balloon catheter and a stent delivery system are disclosed, which includes a shaft portion of which an axially orthogonal cross section of an outer peripheral surface has a polygonal shape, and a balloon which is foldable on the outer peripheral surface of the shaft portion and in which turned-back portions are formed when folded. Portions formed to linearly extend along an axial direction in the turned-back portions are respectively positioned on sides of the polygonal shape. A stent can be arranged on an outer periphery of a balloon in the balloon catheter and expands in response to dilation of the balloon.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: August 27, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Tomoya Komatsu, Noboru Saito