Abstract: A microsurgical device and methods of its use can be used for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. A device can be used for cutting the trabecular meshwork (“TM”) in the eye. The device tip provides entry into the Schlemm's canal via its size (i.e., for example, 0.2-0.3 mm width) and configuration where a ramp elevates the TM away from the outer wall of the Schlemm's canal and guides the TM to first and second lateral elements for creating first and second incisions through the TM. The dimensions and configuration of the device is such that an entire strip of TM is removed without leaving TM leaflets behind and without causing collateral damage to adjacent tissues.

Abstract: A suture needle having a bendable region includes an elongated body having a proximal section, a distal section, and a bendable region located between the proximal and distal sections. The bendable region has a reduced cross-section and/or is made of a superelastic material that is more flexible than the proximal and distal sections of the elongated body for enabling the suture needle to transform from a first configuration having a larger dimension to a second configuration having a smaller dimension. When in the first configuration, the suture needle is larger than an inner diameter of an elongated conduit of a trocar. In order to pass the suture needle through the elongated conduit of the trocar, the elongated body is bent at the bendable region so that the suture needle is smaller than the inner diameter of the elongated conduit of the trocar.

Abstract: A needle and suture assembly includes a needle made of a superelastic alloy, such as Nitinol, including an elongated body having a proximal end and a distal end with a sharpened tip, a suture having a free end juxtaposed with the proximal end of the elongated body of the needle, and a connector disposed between the needle and the suture. The connector includes a first end attached to the proximal end of the elongated body of the needle and a second end attached to the free end of the suture. The connector is made of a material, such as stainless steel, having less elasticity and greater plasticity than the superelastic alloy of the needle.

Abstract: A catheter device for heart repair comprises a leaflet anchor for placement in a leaflet of a heart valve, wherein the leaflet anchor is coupled to the artificial chord; a mechanical gripper device for grasping the leaflet of the heart valve, wherein the gripper device comprises a leaflet anchor channel for housing the leaflet anchor in a folded configuration; and a U-rod wire with a U-shaped rod at one end of the wire, with the free end of the U-shape abutting the end of the leaflet anchor; the gripper device and leaflet anchor being arranged such that when the gripper device grasps the leaflet, the U-rod wire can be used to push the leaflet anchor out of the leaflet anchor channel to pierce the leaflet and form the leaflet anchor into an unfolded configuration permitting hooked formations of the leaflet anchor to secure the leaflet anchor in the leaflet.

Abstract: A wound closure device includes a shaft, a needle, and a housing. The needle includes a first leg portion coupled to a distal end of the shaft, a curved portion, and a second leg portion including a needled end portion terminating at a needle tip. The housing includes a first channel slidingly engaged with the elongated body of the shaft and a second channel slidingly engageable with the second leg portion of the needle. The second channel terminates at an opening defined within a notched section defined in a proximal portion of the housing. The needle is movable to a covered position in which the needle tip is disposed within the second channel of the housing, an advanced position in which the needle tip is disposed distal to the housing, and a retracted position in which the needle tip is disposed within the notched section of the housing.

Abstract: A system for verifying a tool for use in a surgical procedure includes a mechanical interface configured to be affixed to a portion of a patient's anatomy, wherein the mechanical interface comprises at least a first portion having a first diameter and a second portion having a second diameter. The system further includes a probe configured to be inserted into the mechanical interface to establish a checkpoint location, and a computing system configured to determine a location of a portion of the probe when the probe is inserted a maximum distance into the mechanical interface, wherein the location of the portion of the probe establishes the checkpoint location. The computing system is further configured to verify a surgical tool by comparing the checkpoint location to a location of a portion of the surgical tool when the surgical tool is inserted a maximum distance into the mechanical interface.

Abstract: An apparatus for coupling two elongated tissue portions of a subject, such as two portions of a ruptured tendon, comprising first and second repair elements, each repair element comprising a distal end configured for insertion into the tissue portion, an elongated body configured to extend axially within the tissue portion and to engage the tissue, and a proximal end. In some embodiments, at least one of the first and second repair elements comprises, at the proximal end, an integrally formed connector for coupling the proximal end of the first repair element to a proximal end of the second repair element, to attach between the two tissue portions.

Abstract: A needle for aspirating a sample from a sample source and injecting the sample into a liquid chromatography system, the needle including a needle body having a rough textured surface finish for at least a portion of the needle body, wherein the rough textured surface finish reduces a coefficient of friction of the needle body, is provided. Furthermore, an associated method is also provided.

Abstract: A soft anchor assembly according to an exemplary aspect of the present disclosure includes, among other things, a sheath and a flexible strand at least partially surrounded by the sheath.

Abstract: This surgical needle may reduce unwanted and unanticipated tissue distortion and/or tearing and undesirable scar tissue during wound healing. The surgical needle will guide tissue separation more properly along planes of tissue stress, minimizing tissue distortion and improving tissue apposition.

Abstract: The goal is to provide a medical suture needle having, as the material, austenite stainless steel with a structure that is elongated in a fiber form while improving the hardness and flexural strength of the cutting portion. A medical suture needle is made of austenite stainless steel having a structure that is elongated in fiber form, and has a cutting portion and a body portion with a triangular cross-sectional shape that is continuous with said cutting portion. The cutting portion has cutting edges, at least one surface of which is formed by a pressed surface, and which are formed by the intersection of said pressed surface with two sharpened surfaces, and a cutting edge that is formed by the intersection of the two sharpened surfaces. The tip where the various cutting edges and converge is positioned in the center of the pressed surface.

Abstract: Strength of a front end part having a sharp point of a medical suture needle is maintained and resistance when piercing tissue is reduced. There is provided a medical suture needle having a triangular cross section made of austenitic stainless steel having a fibrously extending structure, having two first slanted surfaces (11) ground and sandwiching a ridge (20), and a bottom surface (13) sandwiched between the two first slanted surfaces and ground. The ridge is formed comprising a first cutting blade (1) that is formed by the two first slanted surfaces (11) intersecting, a ridge part (20) that is formed on a body part side of the first cutting blade without the first slanted surfaces (11) intersecting, and a second cutting blade (2) that is formed by two second slanted surfaces (12) ground, intersecting and sandwiching the first cutting blade (1) on a front end side of the first cutting blade (1).

Abstract: A suturing needle is provided for injecting a gold thread. The suturing needle includes a needle body having a sharpened tip part at an upper end thereof. In addition, the suturing needle includes an upper groove provided on the sharpened tip part to hold the gold thread therein, and a lower groove provided near a lower end of the needle body to be opposite to the upper groove. Also, the suturing needle includes a handle part detachably combined with the lower end of the needle body. Various embodiments are possible.

Abstract: A suturing device for suturing a portion of biological tissue includes a needle attached to a suture, a needle holder that releasably holds the needle, and a needle driver adapted to be advanced and retracted substantially parallel to a longitudinal axis of the suturing device. A distal needle holder adapted to releasably hold the needle is positioned in a distal position relative to the portion of biological tissue and a distal end of the needle driver is positioned in a proximal position relative to the portion of biological tissue. The needle is positioned in either the proximal position or the distal position. The needle driver is moved longitudinally in a first direction along a path substantially parallel to the longitudinal axis such that the needle and suture pass through the portion of biological tissue, thereby forming a suture incision through which the suture passes. By repeating the above-described processes, a series of stitches is thereby formed.

Abstract: A needle-suture combination includes a surgical needle having two ends and a suture connection location arranged between the two ends; a suture; and a connection part. A first end of the connection part is connected to the needle at the suture connection location and an opposite second end of the connection part is connected to the suture. The connection part includes a connection part cross section area and the suture includes a suture cross section area. The connection part cross section area is smaller than the suture cross section area. The connection part has a length which is larger than a longest distance from the suture connection location to each of the two ends of the needle.

Abstract: Endoscopic devices and methods used for fastening multiple tissue layers, such as, for example, an endoscopic fundoplication procedure, are disclosed. The endoluminal device includes a tissue fastener, a flexible needle having means for grasping and releasing a portion of the tissue fastener, and a deflector for deflecting and guiding the needle toward the multiple tissue layers.

Abstract: A soft anchor assembly according to an exemplary aspect of the present disclosure includes, among other things, a sheath and a flexible strand at least partially surrounded by the sheath.

Abstract: Devices and methods for performing a transseptal puncture procedure using a device which includes either an untapered or tapered blunt end cannula disposed in an introducer carrying a sharp guidewire disposed longitudinally through the lumen of the blunt cannula, and a blunt end dilator wherein the guidewire is flexible and has an atraumatic shape at its tip. The cannula gives the more flexible introducer a defined shape and steerabilty allowing an ordinarily skilled physician to easily access a selected location on the septal wall of the heart for transseptal puncture and introducer placement thereacross without employing an exposed sharp end needle during the procedure.

Abstract: A suture thread is used to perform suturing without tying part of or the whole of knots that are supposed to be tied during suturing. A suture thread support body prevents an end of the suture thread from being pulled into a suturing site. A needle accommodation body has a shape of a tube having a through-hole through both ends. The suture thread has the suture thread support body and the needle accommodation body.

Abstract: A sling including a material having a plurality of edges. At least one of the edges of the material has a pattern of projections.

Abstract: Methods and devices are provided for attaching soft tissue to bone. In general, a deployment device, insertion assembly, and suture anchor are provided. The insertion assembly is coupled between the deployment device and the suture anchor to allow the deployment device to deploy the suture anchor into bone. Each of the various components disclosed herein can be used alone, in combination with one another, or in combination with various other devices.

Abstract: A fishing hook is plated with, coated with, or contains an antimicrobial substance to treat the impalement wound of a fish caused by the hook. Specifically the hook includes at least one shank; at least one bend that extends from the shank; at least one point defined by a free end of the bend, wherein the fish hook contains a substance whose purpose is to minimize infection and to treat the puncture wound of a fish that is caught. The substance optionally acts to sterilize the hook to reduce the entrance of microbes into the wound when the puncture occurs. The substance may also contain an anti-inflammatory or a pain reliever to reduce the suffering of the fish or of others accidentally injured by the hook.

Abstract: Methods of maintaining airway patency in an airway of a patient. A method includes the steps of wrapping a bioerodable material at least partway around an axis to create a wound bioerodable implant, and coupling two points on the bioerodable material to each other. The invention also provides systems for maintaining airway patency in an airway of a patient that may be used with the methods.

Abstract: A tool for treating a target vessel may include a longitudinally elongated anvil, a channel defined substantially longitudinally in the anvil, and a knife rotatable from a stowed position substantially completely within the channel to an active position in which at least part of the knife extends upward out of the channel, whereby rotation of the knife from the stowed position to the active position incises the target vessel from the inside out.

Abstract: An anchoring device includes an elongate body having a proximal portion and a distal portion. The proximal portion of the elongate body terminates in a free end and the distal portion forms a loop. The loop includes a proximal portion and a distal portion. and further includes a plurality of anchors disposed along a surface thereof. The plurality of anchors are oriented toward the proximal portion of the elongate body to limit movement of the loop through tissue. A pledget is disposed adjacent the proximal portion of the loop. Methods for securing anchoring devices of the present disclosure are also disclosed.

Abstract: Methods and apparatus for providing transapical access to a heart chamber for performing an intra cardiac procedure are described. The apparatus include a helical needle driver, a dilator, a straight access needle, and optionally a guidewire. After entering the heart chamber with the straight access needle, the helical needle driver is used to place a helical suture within the myocardium. After removing the needle driver, the dilator is advanced through the pre-placed helical suture, dilating both a passage and the circumscribing suture. After performing procedure, the pre-placed suture may be closed by proximally retracting an external end of the suture.

Abstract: One aspect provides a suture system including a tool and a suture assembly. The tool includes a head having a proximal portion housing a needle and a distal end spaced apart from the proximal portion by a throat, the needle is movable through a needle exit port formed in the proximal portion of the head to a cavity formed in the distal end of the head. The suture assembly includes suture connected to a suture clip that includes a cylindrical body having a proximal end and a distal end and a slot formed in the cylindrical body between the proximal end and the distal end that allows the cylindrical body to flex in a radial direction, a tab extending from the distal end and configured to be crimped onto an end of the length of suture, and a rib formed on an interior surface of the cylindrical body.

Abstract: A liquid-transfer adapter operatively interposable between an injector and a vial is provided. The adapter has an injector engaging portion configured for fluidly coupling to an injector and a vial coupling. The vial coupling includes a spike that has a spike axis and a tip portion configured for piercing a septum of a vial. The tip portion includes a plurality of facets that meet each other at one or more edges and at least one of the one or more edges is sloped with respect to the spike axis. The spike defines a channel extending therethrough in fluid communication with the injector engaging portion. A channel opening is defined in at least one of the facets and disposed without interrupting the edges.

Abstract: A surgical needle includes a pair of ends, a mid-region extending between the ends, and at least one grasping feature configured for grasping by a suturing instrument. An end of a suture is secured to the mid-region of the needle in a manner such that the end of the suture defines an oblique angle with at least part of the centerline defined by the mid-region of the needle. The end of the suture may be disposed in a hollow portion of the needle. The grasping feature may include a notch such as a scallop. The suture may be pivotally coupled with the needle via a ball or pin. The needle may have one or more sharp points. The sharp point may include three converging cutting edges, at least two planar surfaces bounded by the three cutting edges, and a rounded surface bounded by two of the three cutting edges.

Abstract: A vessel access and closure device places a running suture in the wall of a blood vessel using a rotating helical suture needle that carries the suture along a helical path passing through the vessel wall, then reverses rotation to release a suture anchor attached to the distal end of the suture. A loose helical coil of suture is left behind as the helical suture needle withdraws. The device is withdrawn and replaced with a vessel dilator and an introducer sheath that opens up a larger access opening into the blood vessel and creates a pathway that passes though the helical coil of suture for introducing an interventional device into the blood vessel. After the interventional procedure is completed, the interventional device and the introducer sheath are withdrawn and the running suture is tightened and secured with a suture lock to close the access opening into the vessel.

Abstract: One embodiment is directed to a system for advancing a needle into a tissue structure, comprising: an elongate needle member having a tapered distal tip; an insertion member having proximal and distal ends, the distal end being coupled to the elongate needle member, and the proximal end being configured to be manipulated by an operator; and a tissue interface indentor member coupled to the insertion member and operatively coupled to the elongate needle member, the tissue interface indentor member comprising a distally protruding shape feature configured to contact one or more portions of the tissue structure adjacent to the distal tip of the elongate needle member and change an available angle of penetration between such portions and the distal tip of the elongate needle member as the distal tip is inserted into tissue structure.

Abstract: The present disclosure generally relates to medical devices including sutures and methods of use thereof. The medical device may include a suture having projections angled with respect to a longitudinal axis of the suture and a needle coupled to the suture for inserting the suture into tissue, wherein the projections may allow movement of the suture in a first direction and prevent movement in a second direction. The suture may include an anchor at a distal end such that once the needle is removed, the suture may be pulled in a proximal direction to engage the anchor with an inner tissue wall to tighten and secure the suture within the tissue.

Abstract: An adjustable anchor system for securing tissue to bone, including an anchor having at least one passage extending from a proximal end toward a distal end. The passage defines a restriction such as a restricted opening. The anchor has at least one bone-engaging feature disposed between the proximal and distal ends. The system further includes a first material formed as a closed loop and capable of being placed through a portion of the tissue, and a second filament having a terminal end, a post limb and a sliding knot tied between the terminal end and the post limb to establish an elongated, adjustable-length loop which extends beyond the proximal end of the anchor and captures the closed loop of the first material. The knot of the second filament is restrained by the restricted opening when tension is applied as desired to the post limb to shorten the elongated loop to draw the tissue toward the anchor.

Abstract: A surgical instrument includes first and second members configured to receive tissue therebetween. The first member is adapted to receive suture, the second member is coupled to the first member, and a grasper coupled to the second member engages the suture received by the first member. A method of passing suture includes loading suture into a first member of a suture passing surgical instrument, stabilizing tissue between the first member and a second member of the surgical instrument, passing suture through tissue via the first member of the surgical instrument, holding the passed suture via suture grasper of the surgical instrument, and removing the first member from the tissue.

Abstract: A suturing assembly including a first puncture element including a sharp distal end for puncturing tissue, a second puncture element including a sharp distal end for puncturing tissue, the distal ends of the first and second puncture elements being spaced from each other by a gap, and a spacer arranged for sliding distally and proximally on at least one of the first and second puncture elements.

Abstract: The present disclosure relates to a surgical aimer including a shaft having a proximal portion and a distal portion and a handle coupled to the proximal portion of the shaft. The handle includes a mechanism for coupling the shaft to the handle and releasing the shaft from the handle.

Abstract: A suturing device including an outer bendable body and an inner bendable needle with a freely bendable angle includes a longitudinally extending outer hollow body having a point and a hollow passage and an inner needle portion or part disposed therein. The outer hollow body is constructed and dimensioned to receive a sized suture needle within the hollow passage with slightly close tolerances welded at its base to a point along the hollow body of the outer part and wherein the outer body includes a lower relatively stiff bendable material and an upper portion of relatively malleable material adjacent to and fixed to the lower portion. Further, the outer hollow body is more malleable as it becomes closer to the point.

Abstract: Instruments and methods facilitate reconstruction, repair, and the closure of apertures in soft tissues, including the anulus fibrosus (AF), heart, lung, abdomen, thorax, vascular structures and other organs. Flexible longitudinal fixation components (i.e., sutures) are positioned across apertures in soft tissues, preferably to closes the inlets and/or outlets of such apertures. Tension on the flexible longitudinal fixation components may be used to narrow or close the apertures. Knotless fixation technologies such as suture welding are preferably used to fasten the ends of the flexible longitudinal fixation components. Certain embodiments include an intra-aperture component dimensioned for positioning within a defect in the AF, with one or more components being used to maintain the intra-aperture component in position. For example, the flexible longitudinal fixation component(s) may be anchored to one of the upper and lower vertebral bodies.

Abstract: There is provided a suture needle having a base end surface to which either both ends of a single suture thread or two suture threads are attached allowing easy and secure attachment even of a thicker suture thread than in the past. A suture needle, which is provided with a blind hole along the axis from a base end surface of the suture needle, and a suture thread attached by inserting the suture thread in the blind hole and crimping it, is characterized by having the blind hole opened in two places in the same base end surface, and thereby both ends of a single suture thread or two suture threads may be attached to the needle. Moreover, the blind holes opened in two places may be connected so as to make overall shape of the blind holes in the base end surface have a figure eight shape.

Abstract: A surgical filament snare assembly including an anchor capable of being fixated in bone and having a filament engagement feature. A first filament has a noose with first and second noose limbs connected, preferably slidably, to the filament engagement feature. The first and second noose limbs emerge from the anchor as first and second free filament limbs that are capable of being passed through tissue to be repaired and then passable through the noose. The noose is capable of receiving the free filament limbs and strangulating them when tension is applied to at least one of the free filament limbs and the noose to enable incremental tensioning of the tissue after anchor fixation. Preferably, the snare assembly further includes a flexible sleeve joining at least some portion of the first and second free filament limbs to facilitate passing of the free filament limbs as a single unit.

Abstract: A surgical filament snare assembly including an anchor capable of being fixated in bone and having a filament engagement feature. A first filament has a noose with first and second noose limbs connected, preferably slidably, to the filament engagement feature. The first and second noose limbs emerge from the anchor as first and second free filament limbs that are capable of being passed through tissue to be repaired and then passable through the noose. The noose is capable of receiving the free filament limbs and strangulating them when tension is applied to at least one of the free filament limbs and the noose to enable incremental tensioning of the tissue after anchor fixation. Preferably, the snare assembly further includes a flexible sleeve joining at least some portion of the first and second free filament limbs to facilitate passing of the free filament limbs as a single unit.

Abstract: A surgical filament snare assembly including an anchor capable of being fixated in bone and having a filament engagement feature. A first filament has a noose on a first portion of at least a first limb and has a second portion connected to the filament engagement feature of the anchor. Preferably, at least one free filament limb, which in some embodiments is a length of the first filament and in other embodiments is a second filament, is capable of being passed through tissue to be repaired and has at least one end passable through the noose to enable incremental tensioning of the tissue after the anchor is fixated in bone. The noose strangulates the free filament limb when tension is applied to at least one of the free filament limb and the noose.

Abstract: A trocar needle includes an elongate body having a distal end portion and a proximal end portion, a penetrating tip formed at the distal end portion of the body, and an attachment portion formed at the proximal end portion for attaching a tether thereto. A grip region can further be provided and can be formed for example, at the proximal end portion of the body to facilitate gripping by a surgical grasping device. Additionally or alternatively, a notch or otherwise reduced cross-sectional area can be provided. Such a feature can be formed, for example, at the distal end portion of the body, arranged proximal from a distal end thereof for enhancing haptic perception by a surgeon when utilizing the needle.

Abstract: A pacifier glove is provided. The pacifier glove includes a mitten body having opposing sides and having a closed end and an open end, the opposing sides of the mitten body defining an opening there between, the opening being accessible via the open end. An elastic member is configured on the mitten body and proximate the open end, and a strap member is configured on an opposing side of the mitten body and proximate the open end, the strap member opposing the elastic member. A pocket is configured on an exterior surface of the mitten body, the pocket having exterior and interior surfaces. A pacifier is coupled to the exterior surface of the pocket, and the pocket is configured to be turned inside-out on the mitten body to create an inside-out pocket. Under the condition that the pocket is turned inside-out, the pacifier is repositioned within the inside-out pocket.

Abstract: The present invention relates to a tissue securement system, device and method for endoscopy or endosonography-guided transluminal interventions whereby a ligation or anchor is placed and secured into soft tissue. An objective of this invention is to provide a method to reduce gastroesophageal reflux by endosonography-guided intervention. Specifically, endosonography is used to insert a ligation element through the esophageal wall, through the diaphragmatic crus and into the fundus of the stomach. This ligation element placed from the esophagus and around the Angle of His to create a barrier to gastroesophageal reflux.

Abstract: A surgical needle for use in a circular needle applier comprises a leading end, a trailing end, and an arced body between the leading and trailing ends. The body has a medial face and a lateral face. A plurality of steps on the body are adapted to be engaged by a circular needle applier. The steps are formed by plastically deforming the body without removing material. A length of suture is connected to the trailing end.

Abstract: A suture passer device is provided including a jaw configuration that grasps targeted tissue such as tendons or muscles in a similar manner as existing suture passer devices; however, the device introduces the needle and the attached suture along the axis of the shaft of the device. After grasping the targeted tissue, the needle is deployed by manipulating the handle of the device similar to conventional suture passers however, the needle is deployed in between the opposing jaws and the needle is advanced into tissue along the axis of the shaft as opposed to perpendicular to the shaft as in prior art devices. The invention further includes methods of deploying sutures and anchors. The invention also includes embodiments of jaw designs, and various embodiments of suture passing needles, sutures constructions, and anchor designs. Therefore, the invention also comprises the device in combination with the needles, sutures, and anchors, as well as the needles, sutures, and anchors in separate sub combinations.

Abstract: Needle-stick injuries are associated with considerable risk of morbidity for healthcare workers and patients. The present invention of a handheld surgical suturing device allows tor visualization of surgical field and better control of the suture needle with possible one-hand operation. The device also provides active safety features that protect the surgeon from needle-stick injury.

Abstract: Disclosed is a shaped electrode and dissecting tool configured to aid in controlling the path of an electrode as it is moved into its intended position within the epidural space of a patient. The shaped electrode and dissecting tool is configured with a contoured leading edge having at least one concavity that aids in moving the electrode and dissecting tool through the intended tissues within the patient's body. A variety of concavity contours may be provided and used for particular surgical applications.

Abstract: Methods and devices are provided for securing tissue to bone. In general, a suture leader can have leading and trailing ends, and an inner passageway configured to receive a strand of suture therein. More specifically, the trailing end of the leader can be configured to receive the strand of suture therein to form an overlapping region of suture leader and suture. When the suture is positioned in the leader, an outer diameter of the leading end of the leader can be less than an outer diameter of the over lapping region. The leader can have a lower bending stiffness than the suture so that the leader can be more easily folded into a bend. In certain aspects, the suture leader can be formed from a substantially flexible, braided material so that the leader can be configured to contract when a pulling force is applied to the leader. In another embodiment, the suture leader can have a pre-formed crease configured to mate with a threading tool.