Abstract: Devices and methods for ablating a selected tissue volume, such as for ablating tumor, are disclosed. In certain embodiments, the ablation devices include a low-conductivity, tissue-piercing tip, an adjustment mechanism for selectively adjusting the length of an exposed portion of the electrode, for producing ablation volumes of desired geometry. In other embodiment, the methods allow the adjustment of the length of the exposed electrode portion be carried out by moving an insulative sleeve along the electrode.

Abstract: An electrosurgical apparatus includes a housing having at least one shaft extending therefrom that defines a longitudinal axis therethrough. The shaft operatively supports an end effector assembly at a distal end thereof. The end effector assembly includes first and second jaw members pivotably connected to each other and moveable from an open spaced apart position to a closed position to grasp tissue. An electrically conductive tissue sealing plate is operatively coupled to each of the jaw members. At least one of the jaw members has a serrated edge disposed thereon for selectively sectioning tissue upon rotation of the end effector assembly about the longitudinal axis. The electrically conductive tissue sealing plates are adapted to connect to an electrosurgical energy source.

Abstract: Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like.

Abstract: An apparatus comprises an ultrasonic transducer, a probe portion, the proximal end being coupled to the ultrasonic transducer, ultrasonic waves output from the ultrasonic transducer being transmitted to the probe portion, a storage portion which stores the ultrasonic transducer, a cylindrical casing portion which has a distal end and a proximal end and which is installed outside the storage portion, an electric path provided to extend between an electric contact disposed at the distal end of the casing portion and an electric cable connecting portion provided at the proximal end of the casing portion, and an electric cable which has a distal end and a proximal end, the proximal end being connected to a power supply unit, the distal end being coupled to the electric cable connecting portion, the electric path being disposed between the storage portion and the casing.

Abstract: An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, an inner tissue engaging surface, and an insulating layer disposed therebetween. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The jaws include a tissue-contacting seal plate having obverse and reverse surfaces. A series of ribs extend from the reverse surface of the seal plate into an insulating layer, which, in turn, is affixed to a jaw housing. The ribbed structure of the seal plate reduces thermal spread and edge cutting during vessel sealing procedures, leading to improved surgical outcomes.

Abstract: An electrosurgical vessel sealing instrument having a first and a second opposing jaw member at a distal end thereof, wherein each jaw member includes a jaw housing, a seal plate having a tissue contacting surface and a side wall, and an insulating region disposed on the side wall of the seal plate. The instrument includes the ability to move the jaw members relative to one another from a first position wherein the jaw members are disposed in spaced relation relative to one another to a second position wherein the jaw members cooperate to grasp tissue. The insulating region enables precision overmolding of the jaw housing to the seal plate, while advantageously reducing thermal spread and edge cutting during vessel sealing procedures.

Abstract: An electrophysiology electrode having multiple power connections and electrophysiology devices including the same.

Abstract: A tissue ablation system for treating fibrillation in a patient comprises a steerable interventional catheter having an energy source that emits a beam of energy to ablate tissue thereby creating a conduction block for aberrant electrical pathways. The system also includes a handle disposed near a proximal end of the interventional catheter and has an actuation mechanism for steering the interventional catheter. A console allows the system to be controlled and provides power to the system, and a display pod is electrically coupled with the console. The display pod has a display panel to display system information to a user and allows the user to control the system. A catheter pod is releasably coupled with the handle electrically and mechanically, and also electrically coupled with the display pod.

Abstract: A method of and a system for treatment of atrial tachyarrhythmias. The system includes a set of hemostats having elongated opposing jaws carrying mechanisms for applying ablation energy along the jaws. The jaws having straight and curved configurations selected to allow arrangement of the jaws of along opposite sides of walls of a patient's atrium. Treatment is accomplished by applying of ablation energy to the walls of a patient's artria to create lines of lesion corresponding generally to incisions employed in a Maze type procedure.

Abstract: A surgical cutting and fastening instrument. The instrument comprises an end effector, a shaft connected to the end effector, and a handle connected to the shaft. The handle comprises an electric, DC motor connected to a drive train in the shaft for powering the drive train. The handle also comprises a power pack that comprises at least one charge-accumulating device connected to the DC motor for powering the DC motor.

Abstract: An apparatus and method for closing an opening in a blood vessel wall is disclosed. The apparatus includes at least one member which is extended through a tissue tract formed through the epidermis and subcutaneous layer of skin and through the opening in the blood vessel. The member includes a proximal end and a distal end with the distal end being positionable proximate to the opening in the blood vessel wall. A positive electrode is positioned next to the distal end with a negative electrode being positioned next to the proximal end When the electrodes are energized an electric field is created therebetween, blood cells are attracted to the positive electrode, and a thrombus is formed at the opening in the blood vessel wall. The member may include a balloon at the distal end to temporarily occlude blood flow from the blood vessel to the tissue tract to facilitate formation of the thrombus.

Abstract: Methods and devices described herein facilitate improved treatment of body organs.

Abstract: A sheath system for selectively covering a distal end of an electrocautery blade is provided. The sheath system includes a hub having a body portion defining a lumen therethrough and a sheath having a body portion defining a lumen therethrough. The lumen of the sheath is configured and dimensioned to operatively receive an electrocautery blade therein. The sheath is translatably associated with the hub such that rotation of the hub in a first direction results in axial movement of the sheath in a first direction to expose a distal end of the electrocautery blade and rotation of the hub in a second direction, opposite to the first direction, results in axial movement of the sheath in a second direction to cover the distal end of the electrocautery blade. The hub and the sheath may be concentric with one another.

Abstract: Methods, apparatus, and systems for occluding a left atrial appendage are provided. One embodiment includes an elongate body having a tissue apposition member extendably positioned within a lumen of the elongate body to appose tissue of the LAA. An energy emitting device coupled to the elongate body can be used for emitting high intensity focused ultrasound to the tissues to fuse the tissues.

Abstract: A gas-enhanced electrosurgical method and apparatus for coagulating tissue. The apparatus includes a first tube with a proximal end and a distal end. The proximal end of the first tube is configured to receive pressurized ionizable gas. The distal end of the first tube is configured to deliver ionized gas towards a treatment area. The apparatus also includes at least one electrode positioned to selectively ionize the pressurized ionizable gas before the pressurized ionizable gas exits the distal end of the first tube. The electrode is adapted to operatively couple to an electrical energy source. The apparatus also includes a second tube with proximal and distal ends. The second tube is configured to selectively evacuate the ionized gas and dislodged tissue material from the treatment area.

Abstract: A plasma generator having a dielectric body; a first end wall and a second end wall attached or coupled to each end of the dielectric body to define a cavity within the dielectric body, and wherein the second end wall includes at least one discharge aperture formed therein; at least one gas inlet formed proximate the first end of the dielectric body; at least one anode located within the cavity of the dielectric body, wherein the at least one anode includes at least one anode aperture; at least one hollow discharge nozzle associated with each discharge aperture, and extending from the second end wall to a nozzle aperture, such that when a generated plasma is produced, the generated plasma flows through each discharge aperture, each associated discharge nozzles, and each associated nozzle aperture; and at least one cathode formed at least substantially around a portion of each discharge nozzle.

Abstract: Methods for using a surgical device integrating a suction mechanism with a coagulation mechanism for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source and a fluid source to passively transport fluid along the contacted soft tissue surface in order to push the maximum temperature deeper into tissue.

Abstract: Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.

Abstract: A surgical system including a surgical glove having support systems such as, but not limited to, lights, electrical cautery, suction, and irrigation. The surgical glove may include one or more lights, electrical cautery, suction, and irrigation positioned on distal ends of fingers of the surgical glove. The support systems may be controlled with switches positioned on the fingers upon which each support system is positioned. The switches may be operable with the thumb on the human hand upon which the surgical glove is attached. The surgical system may also include a surgical gown having a connection system for attaching support conduit to the surgical gown. The surgical system enables a surgeon to have a plurality of support systems immediately available and reduces entanglement problems endemic with conventional systems.

Abstract: A surgical device integrating a suction mechanism with a coagulation mechanism is provided for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source. A fluid source to passively transport fluid along the contacted soft tissue surface may be provided in order to push the maximum temperature deeper into tissue.

Abstract: A cardiac ablation instrument capable of removing blood from a treatment area is provided. The instrument includes a catheter configured to deliver a distal end thereof to a patient's heart. The instrument can also include an expandable element coupled to the distal end of the catheter wherein the expandable member is configured to be positioned adjacent a target area thereby defining a treatment area between the expandable member and the target area. Further, the instrument can include an irrigation mechanism configured to dispense an irrigation fluid from the catheter thereby displacing blood from the treatment area. Additionally, the instrument includes an energy emitter configured to deliver energy to tissue within the treatment area. The instrument can also include a contact sensor configured to determine the presence of such blood within the treatment area. Methods for ablating tissue are also provided.

Abstract: A device for coagulating body tissue contains an electrode arrangement comprising a first electrode group and a second electrode group, both of which have strip-shaped electrodes.

Abstract: An electrosurgical apparatus includes two assemblies, one of which is the primary assembly intended for a first surgical procedure, such as cutting tissue, and a secondary assembly intended for a second type of electrosurgical procedure, such as tissue coagulation. The secondary assembly fits over the electrode tip of the primary assembly and makes electrical contact with the electrode tip of the primary assembly. This allows for single instrument surgery whereby the secondary (coagulation) assembly provides bleeding control after the primary assembly has cut tissue. This combination significantly reduces operating time. The secondary assembly has a snap fit over the primary assembly so that it may be readily attached and detached several times during any surgical procedure, as the surgeon alternates between cutting tissue and coagulating the resulting incisions using the apparatus.

Abstract: An electrosurgical suction coagulator is disclosed having improved thermal insulation between the active electrode and adjacent tissue. In embodiments, passive insulation is used to control the transfer of thermal energy from an electrosurgical electrode into surrounding tissue. Braided, closed-sell foam material, and open cell foam materials may be used to thermally insulate the outer surface of a suction coagulator shaft from an inner electrode. In embodiments, a suction coagulator shaft includes an external covering formed from open-cell foam material, which may be saturated with a coolant, such as water or saline, to increase the thermal mass of the shaft. In other embodiments, active cooling delivers coolant to the operative site. In yet other embodiments, a suction coagulator shaft includes a cooling jacket through which coolant is passed to actively cool the instrument.

Abstract: A welding element is provided for applying heat, chemicals, pressure, or any combination thereof to tissues inside a patient's body, e.g., a patent foramen ovale. In one aspect, the welding element is connected to a radio frequency energy source and includes an electrode and a locator. The locator facilitates positioning of the welding element and is capable of moving from an open position to a clamping position. In another aspect, a needle is provided for transseptal puncturing before the application of heat. In yet another aspect, the welding element is configured as a coil. The welding element can be made of Nitinol.

Abstract: A high efficiency electrosurgical electrode with an advanced electrically conductive tip and aspiration port, and a method of conducting an electrosurgical procedure with such electrode. The electrosurgical electrode comprises an electrically conductive tip with a central lumen or “chimney” surrounded by a plurality of protuberances. The central lumen or “chimney” is “self-cleaning” and/or “self-clearing” in that any tissue passing through the central lumen that might cause a clog is quickly denatured by the surrounding electrode and aspirated from the ablation site, so that the probe does not require special consideration by the user (for example, replacement due to total loss of suction). The plurality of protuberances have various forms and geometries that define a plurality of recesses and that, in one embodiment, are provided in a “star-shaped” or partial “star-shaped” pattern.

Abstract: An electrosurgical apparatus for coagulating tissue comprises an elongate tube (3) having a proximal end and a distal end, and having a distal end face (12). The tube comprises one or more first apertures (14) located at the distal end face (12) and one or more second apertures (13) located along the periphery of the tube between the proximal and distal ends. The tube provides a conduit though which ionizable gas can be supplied to the distal end of the tube, and includes at least one electrode (4) for ionizing the ionizable gas exiting either the first or second apertures.

Abstract: An electrosurgical apparatus for coagulating tissue comprises an elongated tube (3) having a proximal end and a distal end, and constituting a conduit though which ionisable gas can be supplied to the distal end of the tube. The tube (3) includes one or more apertures (9) in the tube such that the ionisable gas is capable of exiting the tube in a plurality of different directions. The tube includes at least one electrode (4) for ionising the ionisable gas exiting the one or more apertures, and a shield (11) associated to with the tube (3) and movable so as to obscure at least part of the one or more apertures (9) so as to vary the direction or directions in which the ionised gas exits the tube.

Abstract: A medical probe kit and method of treating abnormal tissue within a patient is provided. The kit comprises a cannula having a shaft, a lumen extending through the cannula shaft, and a first ablation electrode disposed on the distal end of the cannula shaft. The cannula may have a handle mounted to the proximal end of the cannula shaft, and an optional fluid delivery port on the handle in fluid communication with the cannula lumen. The kit further comprises an ablation probe configured to be removably disposed within the delivery cannula lumen. The ablation probe has a shaft and a second ablation electrode disposed on a distal end of the probe shaft, wherein the first and second ablation electrodes are arranged in a bipolar configuration. Preferably, the ablation probe is slidable relative to the delivery cannula, whereby the distance between the first and second ablation electrodes can be adjusted.

Abstract: A swivel device for connection to an ESU pencil, an exhaust port of an ESU pencil with an integrated smoke evacuation system, or an exhaust port of an ESU pencil smoke evacuation shroud attachment includes a fixed member attached to a rotating member. The rotating member allows an electrical cord and/or vacuum tube to twist and coil freely during operation of an ESU pencil with or without the smoke evacuation system.

Abstract: Surgical systems, devices and methods including one or more tissue stimulation elements that, in some instances, may also be used for sensing purposes. Some of the surgical devices also include a tissue coagulation element.

Abstract: An electrosurgical device to generate a plasma stream and method to perform endoscopic or laparoscopic surgery within a patient's body. The electrosurgical device includes an electrode operatively coupled to an electrosurgical generator to receive electrical energy therefrom, the electrode being concentrically disposed within an inner noble gas conduit to form a plasma channel. An outer electronegative gas conduit is disposed in surrounding coaxial relation relative to the inner noble gas conduit to cooperatively form an electronegative gas channel therebetween such that the electrode heats the noble gas to at least partially ionize the noble gas to generate the plasma stream to be directed to the surgical site to perform the surgical procedure while the electronegative gas sustains the plasma stream at the surgical site and dilutes the noble gas adjacent the surgical site. An outer aspiration conduit may be provided to remove fluid and solid debris from the surgical site.

Abstract: A portable, thermal cauterizing forceps device for use in surgery. The device incorporates a pair of ceramic heater elements mounted within the tips of the tines of a forceps. The forceps is used to grasp tissue or blood vessels and apply heat to effect cauterization. The forceps instrument can incorporate a battery and control electronics. The thermal-forceps is of a self-contained wireless, handheld disposable design. The forceps handpiece can be connected to an external power source. The forceps can incorporate a set of rapidly heating ceramic heater elements that may be composed of silicon nitride. An LED provides the operator feedback as to the operating level of the heaters and/or battery reserve. The forceps can include a rechargeable power supply, variable control of the heater temperature, as well as a, digital display of the tip temperature.

Abstract: Devices and methods for cauterizing a tubular vessel are disclosed. A device for cauterizing a tubular vessel can include a hand piece, a tip portion provided at an operative end of the hand piece, one or more probes extending from the tip portion, one or more grasping arms extending beyond the tip portion and movable to grasp a target tissue positioned at or near the tip portion, and a power supply configured to supply energy to the one or more probes.

Abstract: An electrosurgical system has an electrosurgical generator with a multiple-phase RF output stage coupled to a multiple-electrode electrosurgical instrument. The instrument has three treatment electrodes each of which is coupled to a respective generator output driven from, for instance, a three-phase output transformer. Continuous RF output voltage waveforms are simultaneously delivered to respective generator outputs at the operating frequency, each waveform being phase-displaced with respect to the other waveforms. The magnitude of the RF output voltage waveform delivered to at least one of the generator outputs is sufficient to cause tissue vaporisation at the respective treatment electrodes when the system is used for tissue treatment.

Abstract: An ablation catheter system and method of use is provided to endoscopically access portions of the human esophagus experiencing undesired growth of columnar epithelium. The ablation catheter system and method includes controlled depth of ablation features and use of either radio frequency spectrum, non-ionizing ultraviolet radiation, warm fluid or microwave radiation, which may also be accompanied by improved sensitizer agents.

Abstract: Methods and apparatus for joining biological tissue together are provided. In at least one specific embodiment, a method for joining biological tissue together can include applying a biological solder on a wound. A barrier layer can be disposed on the biological solder. An antenna can be located in proximate spatial relationship to the barrier layer. An impedance of the antenna can be matched to an impedance of the wound. Microwaves from a signal generator can be transmitted through the antenna to weld two or more biological tissue pieces of the wound together. A power of the microwaves can be adjusted by a control circuit disposed between the antenna and the signal generator. The heating profile within the tissue may be adjusted and controlled by the placement of metallic microspheres in or around the wound.

Abstract: The use of non-thermal plasma to treat mucus membrane bleeding is described herein. A non-thermal plasma is generated using an apparatus having a first electrode that receives alternating electrical potentials from a power supply. When placed in an appropriate location proximate to tissue, a non-thermal plasma is generated, the second electrode being human tissue, blood, etc. To reduce the likelihood of an arc being generated, potentially causing tissue damage or pain, the first electrode is partially encapsulated by a dielectric. The non-thermal plasma is applied to the area of bleeding for treatment.

Abstract: The endoscopic nasal palatoplasty procedure provides a reduction in the posterior aspect of the soft palate and/or uvula, thereby increasing the area of the nasopharyngeal passage between the soft palate and/or uvula and the back of the nasopharynx. This increased nasopharyngeal area promotes nasal breathing, thereby reducing reliance upon oral breathing and corresponding sleep-disordered breathing syndrome and associated problems such as sleep apnea and snoring. The procedure is performed using a conventional surgical implement, such as a Coblator® or other electro cauterizing or laser cauterizing implement, to ablate and cauterize a series of lesions in the soft palate and/or uvula. The procedure is performed by inserting the surgical implement through one of the nasal passages to access the superior surface of the soft palate and/or uvula.

Abstract: A method and associated electrosurgical apparatus for cutting and/or coagulating living tissue of a mammal. The glow blade cuts and/or coagulates the tissue with a glow blade accompanied by sufficient electrical current across the tissue to enable the cutting and/or coagulating to be performed while the glow blade is heated to a sufficient temperature. The electrosurgical apparatus includes the glow blade, a radio frequency (RF) generator such that a first output of the RF generator is electrically connected to the glow blade, and an energy source coupled to the glow blade. The RF generator is configured to supply sufficient RF power and associated electrical current across the living tissue for performing the cutting and/or coagulating by the glow blade while sufficient energy is being supplied by the energy source to heat the glow blade to a sufficient temperature for performing the cutting and/or coagulating by the glow blade.

Abstract: A method for producing hemostasis of an artery of a patient having a puncture following arterial catheterization including introducing a hemostasis device including at least one electrode into the vicinity of the puncture, supplying an electric current to the at least one electrode, thereby heating blood in the vicinity of the puncture and causing coagulation of the blood and subsequently removing the hemostasis device from the patient.

Abstract: A ring dissector/harvester device for dissecting and harvesting a vessel has a capture tool that is co-axially positioned around the vessel to at least temporarily hold the vessel. A sealing tool is coaxially positioned within the capture tool and is axially movable with respect to the capture tool. The sealing tool and the capture tool are engaged to cauterize a branch from the vessel and to seal the cauterized branch and vessel.

Abstract: An energy delivering probe is used for thermally coagulating and/or constricting hollow anatomical structures (HAS) including, but not limited to, blood vessels such as perforator veins. The probe includes a shaft and an energy source.

Abstract: The invention provides an electrosurgical unit comprising a radio-frequency power source and a pump, with the throughput of fluid expelled by the pump controlled by the RF power level setting and fluid flow rate setting. The invention also provides various electrosurgical devices which may be used with the electrosurgical unit. In one embodiment, the electrosurgical device comprises a first electrode tip spaced next to a second electrode tip with a portion of the first electrode tip facing the second electrode tip and a portion of the second electrode tip facing the first electrode tip, the first electrode tip and the second electrode tip both having a spherical distal end, and a fluid outlet arrangement to expel fluid onto the electrode tips solely at locations remote from the electrode tip portions facing each other.

Abstract: A jaw angle detection system for an end effector assembly includes a first electrical contact that connects to a first jaw member and connects to a generator. A sensor connects to a second jaw member (or an actuator) and connects to the generator, and configured to move relative to the first electrical contact upon movement of the second jaw member (or the actuator) when the first and second jaw members are moved to close about tissue disposed therebetween. Information relating to the position of the sensor relative to the first electrical contact is relayed back to the generator to determine an angle between the first and second jaw members.

Abstract: Methods for using a surgical device integrating a suction mechanism with a coagulation mechanism for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source and a fluid source to passively transport fluid along the contacted soft tissue surface in order to push the maximum temperature deeper into tissue.

Abstract: The present disclosure is directed to a tissue clip for use in electrosurgical procedures. The tissue clip includes an arm having a first electrode formed thereon. The tissue clip also includes a body pivotally coupled to the arm. The body includes a power source and a second electrode.

Abstract: An ablation device, including a catheter and an ablation element incorporating one or more balloons at the distal end of the catheter, has a continuous passageway extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. The ablation device ablates tissue by subjecting it to ultrasound energy, cryogenic energy, chemical, laser beam, microwave, or radiation energy. A probe carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the probe. Pulmonary vein potential is monitored in real time via the electrodes. The probe may have an atraumatic tip with a ball formed at the leading edge. The atraumatic tip prevents any tissue damage such as perforation of heart wall.

Abstract: The invention concerns a flexible application device including a tubular high-frequency catheter with a flexible shaft tube having at least one lumen passing therethrough, a head electrode arranged at the distal end of the catheter, an electric line with a connection for a generator ,and a connecting element arranged at the proximal end of the shaft tube between the shaft tube and the line. An electrically conducting traction element extends in the lumen between the head electrode and the connecting element and is fixedly connected to the head electrode on the one hand and the connecting element on the other hand in such a way and which is of such a tensile strength that all external forces which occur during a treatment and which act on the catheter can be transmitted to the connecting element by way of the head electrode and the traction element.

Abstract: A welding element is provided for applying heat, chemicals, pressure, or any combination thereof to tissues inside a patient's body, e.g., a patent foramen ovale. In one aspect, the welding element is connected to a radio frequency energy source and includes an electrode and a locator. The locator facilitates positioning of the welding element and is capable of moving from an open position to a clamping position. In another aspect, a needle is provided for transseptal puncturing before the application of heat. In yet another aspect, the welding element is configured as a coil. The welding element can be made of Nitinol.