Abstract: A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.

Abstract: The disclosed technology provides a device for sealing an aperture in a tissue of a body lumen. The device comprises a flexible support member having a base having (i) a central portion and (ii) one or more lateral support portions, to engage and/or hold a sealable member of the device against an interior surface of the tissue when the device is in the sealing position. The lateral support portions provide additional support surfaces to engage peripheral portions of the sealable member against the interior surface of the tissue.

Abstract: A convertible nephroureteral catheter is used in the treatment of urinary system complications, particularly on the need for a single surgically delivered device to treat patients who must be seen by an interventional radiologist (IR). In many current procedures, patients need to return to the operating room to remove a previously delivered nephroureteral catheter to exchange this catheter with a fully implanted ureteral stent delivered though the same access site at the flank. The present convertible nephroureteral catheter reduces the need to return for a second surgical procedure. Two weeks after initial implantation, the proximal portion of the convertible nephroureteral catheter extending out from the body may simply be removed. A simple action at the catheter hub allows this proximal portion to be removed, leaving behind the implanted ureteral stent within the patient's urinary system. Other medical procedures, devices, and technologies may benefit from the described convertible catheter.

Abstract: In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other.

Abstract: Controlled deployable medical devices that are retained inside a body passage and in one particular application to vascular devices used in repairing arterial dilations, e.g., aneurysms. Such devices can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning, resulting in precise alignment of the device to an implant target site.

Abstract: An implant delivery system includes a catheter, an implant, and a push body. The catheter extends from a first proximal end to a first distal end. The catheter defines an inner lumen extending through the first distal end. The implant includes a second proximal, a second distal end, and a plurality of resilient barbs. The implant is slidably housed within the inner lumen. The implant is compressed in the inner lumen such that the implant bears against an inner diameter of the inner lumen and the implant is retained within the inner lumen by friction. The push body is slidably housed within the inner lumen of the catheter. The push body is adjacent to the second proximal end of the implant.

Abstract: A vascular graft incorporating a stent into a portion of its length. While various materials may be used for the vascular graft, the graft is preferably an ePTFE graft. The stent is preferably a self-expanding stent, although it may alternatively be a balloon expandable stent. The vascular graft preferably has a continuous inner tubular liner that extends between the opposing ends of the graft and provides a continuous luminal surface for blood contact that is uninterrupted by seams or joints. The length portion of the graft that does not include the stent has a greater wall thickness than does the portion including the stent.

Abstract: A vaso-occlusive device is constructed out of dissimilar metallic materials that are in contact or otherwise in close proximity with one another, thereby causing the device to undergo galvanic corrosion when exposed to an electrolytic medium, such as blood or other body fluid, wherein one of the dissimilar metallic materials is zirconium or zirconium alloy to create a corrosive product including zirconia having a relatively high hardness, a relatively high fracture toughness, and a relatively high stability when the device is implanted in a vasculature site, such as an aneurysm.

Abstract: Apparatus, systems, and methods are provided for monitoring AF episodes, delivering ATP pulses, and/or achieving electrical isolation of the left atrial appendage (LAA) of a patient's heart and/or preventing thrombus formation after electrical isolation. For example, devices are provided that may implanted from within the left atrium, e.g., to isolate the LAA, prevent thrombus formation within the LAA, facilitate endothelialization, and/or deliver pacing.

Abstract: A device for feeding and setting an implant into a blood vessel includes a hollow cylindrical portion formed of an expandable wire mesh netting with a first end and a second end, with a sleeve for receiving the implant in a radially compressed state. The sleeve is arrangeable along a guide wire. The sleeve for receiving the implant in the radially compressed state is formed by an inner sleeve, around which at least one outer sleeve with a distal end and a proximal end is arranged. The implant is arranged in the inner sleeve in such a way that the second end of the hollow cylindrical portion is arranged on the end facing the proximal end of the outer sleeve, so that during setting of the implant, the inner sleeve surrounding the implant can be moved into the outer sleeve in the distal direction so that the implant expands, beginning from the second end.

Abstract: In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other.

Abstract: A method for treating an intestine with an expandable scaffolding expanded within the intestine. After placing the expandable scaffolding at a target location, such as across a fistula, the first and second end portions of the expandable scaffolding are radially expanded such that the first and second end portions contact an inner surface of the intestine on opposing sides of the fistula, anchoring the first and second end portions to the intestine. Radially expanding the first and second end portions foreshortens the medial portion along the longitudinal axis such that the first and second end portions are drawn closer together along the longitudinal axis as the medial portion foreshortens to close the fistula.

Abstract: This invention relates to an aneurysm occluder, and more particularly but not exclusively, to an endovascular aneurysm occluder that can be inserted into an aneurysm cavity by using endovascular surgical procedures. The aneurysm occluder, includes a resiliently deformable cage (2) made of a mesh structure in which the mesh structure is cylindrical in cross section and closed off at opposite ends, where the opposite ends are held and closed off with shanks (4).

Abstract: A stent has a tubular shaped framework that includes a plurality of vertices that are each defined by a pair of struts. A plurality of induction responsive muscles are associated, respectively, with one of the plurality of vertices by being attached to each strut of a pair of struts. The induction responsive muscles have a relaxed state at body temperatures, and have a contracted state at an elevated temperature greater than body temperature. If the stent has an initial unsatisfactory implant orientation or position or other expansion irregularity, the application of an electromagnetic induction field may be applied to temporary 11 reduce the diameter of the stent to adjust its positioning and/or orientation.

Abstract: A delivery device for an implantable medical device includes an inner shaft extending in a longitudinal direction and an outer sheath adapted to surround at least a portion of the inner shaft, the outer sheath being slideable relative to the inner shaft in the longitudinal direction. A compartment defined between the inner shaft and the outer sheath is adapted to receive the medical device in an assembled condition. A retaining assembly positioned at one end of the compartment includes a first member rotatable with respect to the inner shaft, and a second member rotationally fixed with respect to the inner shaft. The medical device includes at least one retainer adapted to be received within at least one retainer slot of the first member. This arrangement enables the medical device to rotate within the compartment as the delivery device is advanced to an implantation site.

Abstract: An implantable device for regulating blood flow through a blood vessel comprising an elongated support dimensioned and configured to be implanted in a blood vessel. The support includes a linking member linking axially spaced apart portions to one another. A valve membrane extends between the axially spaced apart support portions and includes first region folded over the first linking member and attached thereto and a second region adjacent the first region and unattached to the first linking member. The second region is movable between a first position to enable blood flow and a second position to inhibit blood flow.

Abstract: A pre-loaded prosthesis delivery device is described. In one example, the prosthesis delivery device is pre-loaded with a single wire that allows the device to be tracked into place within a vessel and also facilitates cannulation of a branch vessel. The delivery device further comprises a prosthesis that is releasably coupled to a delivery catheter by using two attachment wires to secure the proximal end of the prosthesis to the delivery device in a tri-fold configuration.

Abstract: Exemplary embodiments comprise AV fistulas and other anastomotic devices for creating new or reinforcing existing side-branch vessels, and/or bridging neighboring vessels together. An exemplary embodiment may comprise a sidewall port, such as a flanged sidewall port, and/or flow frame design, such as a partially bare, flexible stent or a whisk, for purposes of creating a transmural flow. Another exemplary embodiment may comprise a compliant vessel support to aid in the transition from device to vessel and/or vessel to device, and to promote vessel dilation.

Abstract: The present invention provides devices and methods for fabricating and deploying an implantable device within the body. The invention is particularly suitable for delivering and deploying a stent, graft or stent graft device within a vessel or tubular structure within the body, particularly where the implant site involves two or more interconnecting vessels. The delivery and deployment system utilizes a plurality of strings which are releasably attached to the luminal ends of the implantable device.

Abstract: This invention gives physicians in situ control to create differences in wall porosity between different areas of a stent wall. This enables a physician to customize the stent within a blood vessel to selectively block blood flow to an aneurysm with a low-porosity area of the stent wall, but allow blood flow to nearby branching vessels through one or more high-porosity areas of the stent wall. The method comprises inserting a stent into a blood vessel and, in situ, expanding the stent in a non-uniform manner, thereby causing one or more areas of the stent wall to have a lower post-expansion porosity than the rest of the stent wall. With this invention, physicians can selectively block blood flow into an aneurysm while maintaining blood flow into nearby branching vessels, even in tortuous and complex vessel configurations.

Abstract: A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal by of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

Abstract: An apparatus and associated surgical method for repairing abdominal aortic aneurysms is disclosed. The apparatus includes first and second stent grafts made from a metal form structure in combination with a flexible fabric, and a flexible guidewire detachably attached to the first stent graft. The first stent graft has an upper tubular body which defines an inlet, and a lower bifurcation which includes a first tubular leg defining a first outlet, and a second tubular leg defining a second outlet.

Abstract: A prosthetic valve assembly that includes a stent, a tissue sleeve and an anchoring mechanism. By loading the three components of the valve assembly into a delivery catheter in a series formation, such that no two components are located within each other, the size of the delivery catheter can be reduced.

Abstract: The invention relates a sheath that is affixed to a body lumen, proximal to an anastomosis site. The sheath includes a sleeve defining a passage. A grasping structure is positioned distally of the distal opening of the sheath to facilitate elongation of the sleeve from a first length to a second longer length. A method for using the sheath is also disclosed.

Abstract: An endovascular graft delivery system includes an endovascular prosthetic device and one or more trigger wires deployably engaging portions of the endovascular prosthetic device. An electrical element is positioned at a proximal end of a trigger wire. The electrical element is in signal communication with the trigger wire to communicate operational signals over the trigger wire. The operational signals may be power or control signals to assist with positioning the endovascular prosthetic device at a desired deployment location.

Abstract: The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device. In some embodiments, the methods and apparatus may be used as an adjunct to percutaneous heart valve replacement. In some embodiments, the apparatus and methods may provide a medical practitioner with feedback, monitoring or measurement information, e.g., information relevant to percutaneous transcatheter heart valve replacement.

Abstract: The invention relates to an endoprosthesis (1), in particular a vascular or cardiac endoprosthesis (1), having a body (2) and also one or more thrombogenic elements (3) that are fixed to the endoprosthesis (1) and that are able to extend a distance away from the body outside the latter. The endoprothesis comprises means (33) for selectively retaining the thrombogenic elements near the body (2). The release of the one or more thrombogenic elements, after the endoprosthesis has been fitted in place by a conventional method via a sheath, promotes thrombosis.

Abstract: An arrangement for temporarily retaining a side arm (36) of a stent graft (30) in a selected position during loading thereof onto a deployment device, the side arm extending from an ostium (38) in the tubular body (32) and substantially helically around and along the tubular body to an open end (40). A first tie down wire (48) is stitched through the tubular body and through the side arm and then through the biocompatible graft material of the tubular body at the open end of the side arm. The stent graft can then be loaded into a sheath of a deployment device for the stent graft. There can be a second tie down wire (50) stitched through the biocompatible graft material of the tubular body and through the side arm and then through the biocompatible graft material of the tubular body at the ostium end of the side arm. The first and/or second tie down wires can be withdrawn after the stent graft is loaded into the sheath or left in place until delivery.

Abstract: A pusher assembly for a stent delivery device includes a distal end of an elongate member and a stent-engaging member having proximal and distal ends. The proximal end of the stent-engaging member is mechanically coupled to the distal end of the inner member by a connector, or the proximal end of the stent-engaging member is at least partially inside the distal end of the elongate inner member. The stent-engaging member includes a portion that radially outwardly extends towards the distal end of the stent-engaging member, or the stent-engaging member includes a portion that radially outwardly extends towards the distal end of the stent-engaging member. The stent-engaging member is configured to move a stent when distally advanced and configured to not move a stent when proximally retracted. A stent delivery device includes an elongate outer member, an elongate inner member coaxially positioned within the outer member, and the pusher assembly.

Abstract: A stent graft has a tubular side arm which can be angled proximally and distally and from side to side. The wall of the stent graft in the vicinity of the side arm has a loose fold of the graft material and the side arm is fastened to the loose fold of graft material. The tubular side arm has an inner end and an outer end and is fastened into the loose fold of graft material by a circumferential fastening around the tubular side arm between the inner end and the outer end so that the tubular side arm extends partially within the tubular body of the stent graft and partially outside the tubular body of the stent graft. The loose fold of graft material can be formed by the graft material defining a recess in the wall of the stent graft. To enable movement or angulation proximally and distally and from side to side the loose fold of graft material is provided both proximally and distally of the tubular side arm and circumferentially to each side of the tubular side arm.

Abstract: A fenestrated stent graft (1) with a tubular side arm (11) extending therefrom in which the side arm can be turned inside out to extend into the stent graft during deployment of the stent graft and extended out during deployment. Also disclosed is a deployment device (19) for such a side arm stent graft which has a deployment catheter (26) and a side arm guide (32), the side arm guide is releasably fastened at a proximal end to the branch tube (11) and is able to be moved independently of the deployment catheter such that the branch tube can be extended from the tubular body of the stent graft while it is fastened onto the side arm guide. The side arm guide can be formed from a side arm catheter (32) and a side arm guide wire (34) carried in the side arm catheter.

Abstract: A delivery device includes a guidewire catheter and a delivery assembly extending about the guidewire catheter. The delivery assembly includes a locking mechanism that selectively engages a proximal handle of the delivery assembly with a push rod to which a vascular prosthesis is directly or indirectly attached. When an actuator selectively disengages the proximal handle from the handle body, rotation of the proximal handle is independent of longitudinal movement of the vascular prosthesis relative to the handle body, whereby the proximal handle can be moved along the handle body with rotation.

Abstract: An improved delivery system for an implantable medical device includes a retention sheath having a proximal end, a distal end, and an inner lumen extending from the proximal end to the distal end. The implantable medical device is disposed within the inner lumen of the retention sheath, which restrains the implantable medical device. A plurality of substantially incompressible rings are disposed within the inner lumen of the retention sheath in a stacked co-axial configuration that extends from the proximal end of the retention sheath in a pre-deployment position to a proximal end of the implantable medical device. Each ring in the plurality of separate rings abuts at least a portion of an adjacent ring. The plurality of separate rings is configured to prevent the implantable medical device from moving toward a proximal end of the retention sheath when the retention sheath is moved from the pre-deployment position to a deployment position.

Abstract: Prosthesis delivery devices and methods are provided that enable precise control of prosthesis position during deployment. The prosthesis delivery devices may carry multiple prostheses and include deployment mechanisms for delivery of a selectable number of prostheses. Control mechanisms are provided in the prosthesis delivery devices that control either or both of the axial and rotational positions of the prostheses during deployment. This enables the deployment of multiple prostheses at a target site with precision and predictability, eliminating excessive spacing or overlap between prostheses. In particular embodiments, the prostheses of the invention are deployed in stenotic lesions in coronary or peripheral arteries, or in other vascular locations.

Abstract: A stent graft can be held in place on the outside of the thoracic arch by a hypodermic needle tube which passes through a bore of the stent graft and back to the user. A center tube tethered to the stent graft at an end distal to the user is employed to hold the stent graft within the pulsatile blood flow, preventing the stent graft from collapsing during deployment. The position of both the hypodermic needle tube and the center tube can be controlled by the user by a control handle.

Abstract: A method of deploying an eversible branch stent-graft includes deploying the eversible branch stent-graft into a main vessel such that a collateral opening in a main stent-graft of the eversible branch stent-graft is aligned with an ostium of a branch vessel emanating from the main vessel. A branch stent ring suture threaded though outer exposed crowns of an outer stent ring of the branch stent-graft is grasped and pulled through the collateral opening to evert the branch stent-graft into the branch vessel as a branch anchor suture is removed to release a protruding end of a branch stent-graft from a proximal end of the main stent-graft.

Abstract: A delivery system assembly includes an outer tube, an inner member, extending within a lumen of the outer tube, and a deflectable shaft, extending within the outer tube lumen and around the inner member; the tube and inner member are longitudinally moveable with respect to the shaft, and a distal end of the inner member is located distal to the shaft within the tube lumen. A medical device can be loaded into the tube lumen, along a distal-most portion of the tube, and contained between the inner member and a distal opening of the tube lumen. Deflecting the shaft orients the distal-most portion for navigation of the assembly, and, when the distal end of the inner member is engaged within the tube lumen, distal movement of the tube, with respect to the shaft, causes similar distal movement of the inner member and the loaded medical device toward an implant site.

Abstract: A system for treating an aneurysm comprises an elongate flexible shaft and an expandable member. An expandable scaffold is disposed over the expandable member and may be expanded from a collapsed configuration to an expanded configuration. A double-walled filling structure is disposed over the scaffold and has an outer wall and an inner wall. The filling structure is adapted to be filled with a hardenable fluid filing medium so that the outer wall conforms to an inside surface of the aneurysm and the inner wall forms a substantially tubular lumen to provide a path for blood flow. In the expanded configuration the scaffold engages the inner wall of the filling structure. A tether is releasably coupled with the filling structure and the flexible shaft thereby constraining axial movement of the structures relative to each other.

Abstract: Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.

Abstract: Adipose tissue has proven to serve as an abundant, accessible, and rich source of endothelial or vascular endothelial cells suitable for tissue engineering. We describe a detailed method for the isolation and purification of endothelial cells using purified enzymes and antibody-based selection. The cells can be obtained from liposuction procedures and used in vascular grafts.

Abstract: Harvesting of Bilateral internal thoracic arteries under direct vision, through a 2 inch left minithoracotomy, without robotic/thoracoscopic assistance and then using these arteries as a composite Y conduit for coronary artery bypass grafting has never been done or described before. The aim was to develop a technique, where bilateral internal thoracic arteries are harvested directly under vision via a 2 inch left minithoracotomy, without robotic/thoracoscopic assistance and complete off pump revascularization of the myocardium done using the internal thoracic arteries as a composite Y conduit. The “Nambiar Technique” which has never been done or described before, encompasses using a 2 inch left minithoracotomy through which the bilateral internal thoracic arteries are harvested directly under vision and multivessel total arterial coronary artery bypass grafting done using these conduits.

Abstract: A deployment assembly (10) for an introducer used for introducing into a patient a stent or other device, the deployment assembly including a housing 30 carrying a sprung loaded (90) actuator (44,50). The actuator includes a toothed wheel (50) carrying a spool (48) around which a retraction strap (44) can be wound. The strap (44) is coupled to a body member (26) of the introducer and through this to the outer sheath (14) thereof. A trigger (16) is provided for operating the actuator (44, 50). When the trigger (16) is pressed, the actuator winds, under the force produced by the spring (90), the strap (44) to thereby retract the outer sheath (14) so as to expose and then deploy the device carried on the introducer. The mechanism is such that a surgeon need not expend his own energy to retract the outer sheath (14) since this force is provided by the spring (90).

Abstract: A stent-graft has a closed web end configuration in which endmost stent crowns do not extend beyond an end or edge of a tubular graft. In order to couple the stent-graft to tip capture fingers or prongs of a delivery system, the stent-graft includes a ring woven between the endmost crowns of an end stent. When end stent is in a compressed delivery configuration, sections of the ring between adjacent endmost crowns form attachment loops that longitudinally extend beyond the end of the tubular graft for engaging the tip capture fingers of a delivery system. When the end stent is in an expanded fully deployed configuration, the attachment loops retract back to the stent so that the ring is a circular band having a diameter substantially equal to the expanded diameter of the stent.

Abstract: Various embodiments of the present invention provide a conduit device including an attaching device configured for defining a helical pathway through a tissue wall and complementary ring in cooperation for securing the device within an aperture defined in the tissue wall. Some embodiments of the present invention further provide a system for implanting a conduit device in a tissue wall. More specifically, some embodiments provide a system including a coring device for defining an aperture in a tissue by removing and retaining a tissue core and securely implanting a conduit device therein so as to provide fluid communication between a first and second surface of the tissue wall via the conduit device.

Abstract: A delivery system including an inner catheter with a reinforcing element and an outer catheter having a proximal end attached to a movable member. An abutment element may be attached to a distal end of the reinforcing element, configured to engage an implantable device disposed between the inner catheter and the outer catheter.

Abstract: A catheter assembly includes a catheter, including an inner member and a sheath, extending from a handle. The handle includes a housing, a braking assembly, a carriage and a carriage driver. The braking assembly comprises a braking element within the housing interior and a braking element rotator. The carriage comprises at least one carriage braking surface engaging the braking element. The carriage driver, such as a spring, biases the carriage towards the proximal end of the handle. The inner member has a proximal end secured to the housing. The sheath has a proximal end secured to the carriage. Rotating the braking element causes the carriage to move proximally as the carriage braking surface slides along the braking element. This causes the sheath to move proximally relative to the inner member.

Abstract: A total aortic arch reconstruction graft, including a first, hollow cylindrical segment in the shape of an aortic arch, a second, hollow cylindrical segment having a first end joined to the second end of the first segment, and a second end adapted to be inserted into the descending aorta of a patient, the second segment having an expandable outer wall covered with an expandable stent, and a collar having a diameter larger than the diameter of said first segment, the collar located at a juncture where the first end of the second segment is joined to the second end of the first segment, with a plurality of separate, non-absorbable double-armed sutures pre-attached to the collar. A surgical procedure for total replacement of a patient's aortic arch is also disclosed.

Abstract: An endovascular perfusion stent graft is provided that can include a graft device, a balloon, and a perfusion port. The graft device can be configured to be inserted into a vessel. The balloon can be configured to temporarily restrict passage of air or fluid through the vessel when the balloon is temporary inserted into the graft device. The perfusion port can be configured to selectively allow passage of the fluid or the gas through the balloon and to the vessel. The perfusion port can be connected to another perfusion port or to a collection device, such as a heart lung machine. The vessel can be one of an ascending aorta, a descending aorta, or an arch of an aorta.

Abstract: A bifurcated stent graft for animal or human implantation and method of delivery thereof. The device stent graft employs a first component having an axial passage communicating with the axial cavities of a second leg and longer first leg. A separate leg extension is engageable to the second leg. A first catheter engages the first component for translation to the implantation site and a second catheter engaged with the first is provided with a prepositioned guide wire inside the second leg which may be employed to easily position a guide wire for engagement of the second leg with the leg extension.

Abstract: A device for occluding a septal defect is provided. In general, the occluding device has a contracted state that allows the occluding device to be received within a delivery device for deployment to the site of the defect and an expanded state that is achieved when the occluding device is deployed from the delivery device. The occluding device has a proximal portion, which may be substantially circular, a distal portion, which may be substantially ovaloid, and a connecting portion extending between the two. The distal portion may define first and second outer parts at opposite ends of the major axis, which may be bent or curved. The configuration of the proximal and distal portions allow the occluding device to securely engage the septal wall and be kept in position at the septal defect without causing substantial interference with the functioning of adjacent heart structures.