Ear Or Nose Prosthesis Patents (Class 623/10)
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Publication number: 20140343674Abstract: A prosthetic element enables the stapes footplate to be connected to the foot of a middle ear ossicular prosthesis. The prosthetic connection element is of biocompatible material and forms part of the foot or is connected or connectable to this latter, and includes a body provided with a flat surface intended to rest on the footplate and having an area sufficient to prevent reabsorption of the footplate osseous tissue as a result of the pressure which the ossicular prosthesis exerts on the footplate. The prosthetic element includes at least two pointed projections projecting from the flat surface and intended to penetrate the footplate.Type: ApplicationFiled: May 14, 2014Publication date: November 20, 2014Inventor: Franco BEONI
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Patent number: 8888846Abstract: An ossicle prosthesis has, at on one end, a first fastening element for connection to the tympanic membrane or a component of the ossicular chain, on the other end, a second fastening element for connection to a further component of the ossicular chain, or directly to the inner ear, and a connecting element that connects the two fastening elements in a sound-conducting manner, and it also includes an elongated applicator for transferring the ossicle prosthesis from a sterile packaging to the surgical site and for insertion into the middle ear or the auditory meatus, with a free end extending away from the prosthesis and used for handling purposes, and with an engagement part which is initially fastened to the prosthesis in a non-positive or form-fit manner, or via a material bridge which may be broken off or sheared off, and which may be detached and removed together with the applicator once the prosthesis has been inserted into the ear.Type: GrantFiled: January 20, 2010Date of Patent: November 18, 2014Assignee: Heinz Kurz GmbH MedizintechnikInventors: Uwe Steinhardt, Heinz Kurz, Daniel Felix Awengen
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Patent number: 8889123Abstract: The invention relates to compositions comprising a hydrogel material that comprises a glycosaminoglycan polymer, adipose tissue and a compound of the structure where X1 and X5 are independently CH or N; X7 is NH, O or S; X8 and X9 are independently CH or N; R13 is an optionally substituted aryl or optionally substituted heteroaryl and R14 is C1-6 alkyl, optionally substituted aryl or optionally substituted heteroaryl. The composition is administered to a site of a soft tissue condition including those of breast tissue. The hydrogel material can be porous or of solid particles. The glycosaminoglycan polymer can be a hyaluronan polymer.Type: GrantFiled: February 16, 2012Date of Patent: November 18, 2014Assignee: Allergan, Inc.Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
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Patent number: 8883139Abstract: The invention relates to compositions comprising a hydrogel material that comprises a glycosaminoglycan polymer, adipose tissue and a compound of the structure The composition is administered to a site of a soft tissue condition including those of breast tissue. The hydrogel material can be porous or of solid particles. The glycosaminoglycan polymer can be a hyaluronan polymer.Type: GrantFiled: February 16, 2012Date of Patent: November 11, 2014Assignee: Allergan Inc.Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
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Patent number: 8864774Abstract: Systems and methods are provided for automatically forming an incision in a tympanic membrane of an ear and placing a tympanic membrane pressure equalization tube into the incision. The systems include a housing with a shaft extending therefrom. A mechanism is disposed within the housing. A distal end of the shaft is placed against a tympanic membrane, and the mechanism is triggered to causes the tympanic membrane to be automatically incised and dilated and a tympanic membrane pressure equalization tube to be placed in the dilated incision.Type: GrantFiled: July 15, 2010Date of Patent: October 21, 2014Assignee: Acclarent, Inc.Inventors: Greg Liu, Rohit Girotra, John H. Morriss, Julie D. Vrany, Hung V. Ha, Bryan Knodel, Jeffrey A. Walker, Thomas Daniel Gross, Mathew D. Clopp, Bernard H. Andreas
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Publication number: 20140303728Abstract: An ossicular prosthesis formed as a sound-conducting, elongated prosthesis body has a first coupling element designed as a tympanic membrane top plate or a clip or a connecting piece to an actuator end piece of an active hearing implant and a second coupling element provided with an access opening into a receiving space designed as a bell or a clip for a mechanical connection of the prosthesis to the head of the stapes. The second coupling element has a backing section on an inner surface of the receiving space as an axial extension of the prosthesis body. The backing section protrudes from the prosthesis body into the receiving space. In an implanted state, the backing section bears against a head of the stapes and prevents a formation of a hollow space between the stapes and an inner surface of the receiving space in an axial extension of the elongated prosthesis body.Type: ApplicationFiled: April 7, 2014Publication date: October 9, 2014Applicant: HEINZ KURZ GMBH MEDIZINTECHNIKInventors: Uwe Steinhardt, Seilesh Babu, Heinz Kurz
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Publication number: 20140303727Abstract: A device for use in the repair of an ear drum in a subject in need of such treatment, said device: having a tensile strength Youngs Modulus between approximately 12.5 and 40 MPa; comprising one or more membrane layers, wherein at least one membrane layer comprises a plurality of pores; and wherein the device can support proliferation, migration and/or adhesion of cells selected from the group comprising at least any one or more of: keratinocytes, fibroblasts, vascular cells, mucosal epithelial cells, and stem cells.Type: ApplicationFiled: July 11, 2012Publication date: October 9, 2014Applicant: EAR SCIENCE INSTITUTE AUSTRALIAInventors: Marcus Atlas, William Brett Robertson, Robert Jeffrey Marano, Sharon Leanne Redmond, Peter Luke Santa Maria, Brett Levin, Bing Mei Teh
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Publication number: 20140303642Abstract: An electronic control device assists in the insertion of an implant into the body of a patient, and allows the implant to be arbitrarily altered in shape by applying control signals. Patient-specific geometric body data from a body region into which the implant is to be introduced is input and stored. Computer-aided simulation of the insertion operation uses the patient-specific body data as a basis for simulating the insertion operation to produce actuation data which control the arbitrary alteration in the shape of the implant. The control device outputs the actuation data to the implant in the form of control signals on the basis of a sensed or calculated current introduction position of the implant according to the prior simulation.Type: ApplicationFiled: July 12, 2012Publication date: October 9, 2014Inventors: Sonja Dudziak, Thomas Fau, Thomas Lenarz, Omid Majani
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Patent number: 8852251Abstract: A fixation system for a bone conduction device is disclosed. An abutment is coupled to a bone anchor such that vibrations applied to the abutment pass into the bone anchor. The abutment defines a conduction path to the bone anchor such that vibrations applied to the abutment are transferred to the bone anchor. The abutment comprises a plurality of interlocking stacked plates disposed adjacent the bone anchor, wherein the plates form part of the conduction path. The fixation system also comprises a vibratory coupler extending from the bone conduction device, comprising a second conduction surface and a magnet, wherein the magnet attracts to the abutment so as to couple the second conduction surface to the abutment, thereby enabling vibrations to pass through the conduction path. The plates are configured to slide laterally in response to tangential forces incident upon the abutment.Type: GrantFiled: July 3, 2008Date of Patent: October 7, 2014Assignee: Cochlear LimitedInventor: John Parker
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Patent number: 8852277Abstract: A system and method for correcting misshaped ears using a molding device having one or more braces supporting a scaphal mold. The one or more braces and the scaphal mold are adapted to retain the helix and the helical rim of a misshaped ear within a space defined between the one or more braces and the scaphal mold, and to maintain a substantially correct anatomical shape of the helix and the helical rim.Type: GrantFiled: March 29, 2012Date of Patent: October 7, 2014Inventors: Henry Stephenson Byrd, C. Kenneth French, Garrett Barker
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Patent number: 8834567Abstract: A middle ear ossicle prosthesis in which the component for ossicular attachment comprises a surface bearing a plurality of discrete projections facing the ossicle to which it is attached which minimize total contact between the prosthesis and the ossicle. The prosthesis may comprise a loop forming a partial circle for encircling an ossicle, a piston for transmitting vibrations from the loop to the inner ear, and a rod solidly connecting the loop to the piston. The loop may have an upwardly turned end to facilitate placement of the loop over the ossicle. The projections may be provided in one row, two rows, or may be otherwise arrayed, and may be dissimilar from one another in configuration and dimensions.Type: GrantFiled: June 15, 2012Date of Patent: September 16, 2014Inventor: Mark Matthew Scheurer
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Publication number: 20140249626Abstract: An expansible ear canal insert for treating TMJ disorders and headaches which acts directly on the TMJ and associated ligament and muscle structures to reduce stress and loads placed on the articulator disc located between the temporal bone and the mandible, as well as supportive muscles and ligaments near the TMJ. The insert is adapted to expand by application of body heat. In the expanded condition, the insert provides support to the TMJ and associated ligament and muscle structures.Type: ApplicationFiled: April 15, 2014Publication date: September 4, 2014Applicant: TMJ Health LLCInventors: William Coole, Lawrence G. Clayton
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Patent number: 8821575Abstract: Methods and devices for rhinoplasty and treating nasal valve stenosis are disclosed herein. The nasal valve acts as a flow-limiter and can contribute to airway obstruction if resistance within the nasal valve is excessive. In one embodiment, a system for treating nasal valve stenosis includes a first elongate implant and a second elongate implant configured to support the nasal valves when implanted. The implants can be coupled together by connecting elements, such as eyelets, tethers, complementary socket joints, and button-rivet supports.Type: GrantFiled: September 19, 2011Date of Patent: September 2, 2014Assignee: Koninklijke Philips N.V.Inventors: Erik Van Der Burg, Michael Dineen, Mark Hirotsuka, Jasper Jackson, Andrew Frazier, Chad Roue
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Publication number: 20140243975Abstract: Described are implants for placing in a body, tools for delivering the implants, and systems and methods for using implants and tools for placing in a body and more particularly to nasal implants, tools for delivering nasal implants, and systems and methods for using such implants and tools. A tool may include a hand-held implant delivery device that cuts, holds, moves, orients, inserts, or shapes an implant. An implant may be a biodegradable, longitudinal implant that may be oriented for implantation by an implant delivery device.Type: ApplicationFiled: February 27, 2014Publication date: August 28, 2014Inventors: Iyad S. SAIDI, Michael H. ROSENTHAL, Donald A. GONZALES, J. Cameron LOPER, Marcus A. HADLEY, Jamie L. INGRAM, Cheng Q. REN, Charles P. LUDDY, Leon A. MARUCCHI, Bruce C. GRAY, R. Andrew CARLTON
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Publication number: 20140228954Abstract: A vestibular implant fitting system is described for fitting a vestibular implant to an implanted patient. An event processing module is configured for monitoring extra-clinical operation of the vestibular implant and collecting extra-clinical implant operation information. A signal processing fitting module is configured for determining a body response characteristic of the implanted patient to a vestibular implant stimulus signal during a response measurement period, and setting an operating characteristic of the vestibular implant based on the body response characteristic and the extra-clinical implant operation information.Type: ApplicationFiled: April 18, 2014Publication date: August 14, 2014Applicant: MED-EL Elektromedizinische Geraete GmbHInventors: Roland Hessler, Andreas Jäger
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Publication number: 20140228953Abstract: A scaffold for reshaping the cartilaginous portion of an ear. The scaffold is formed of shape memory material and in the form of a horseshoe shape, or is formed from a thermoplastic pliable material.Type: ApplicationFiled: March 28, 2012Publication date: August 14, 2014Applicant: NORTHWOOD MEDICAL INNOVATION LIMITEDInventors: Norbert Kang, Marie-Claire Haines
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Patent number: 8784488Abstract: A method for non-surgically treating an internal nasal valve of a patient comprising, injecting a working device into the internal nasal valve of the patient, wherein the injected working device in the nasal tissue causes an alteration of an internal or external nasal valve. A device introduced by injection into the nose, allowing for structural support or filling of defects in the nose, and causing a change in external shape of the nose. The device and inserts and implants described also have use in cosmetic applications relating to the facial tissue.Type: GrantFiled: January 11, 2012Date of Patent: July 22, 2014Assignee: Spirox, Inc.Inventor: Iyad Saidi
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Patent number: 8764826Abstract: A middle ear prosthetic device including: a columellate prosthesis, one end of which is connectable to the stapes or to its remaining footplate; an annular element of bioinert metal insertable into the auditory tube after suitable milling; an elastic elongated element of bioinert material, disposed transversely to the annular element, a first end of the elongated element being rigid with the annular element while its second end is free and to it there being connected the other end of the columellate prosthesis; for supporting the neotympanum, a tensostructure of wires of non-reabsorbable bioinert material fixed taut to the interior of the annular element to support the neotympanum, the distance between the wires being such as to provide the surgeon with a sufficient view of the surgical field, the elongated elastic element interfering with the tensostructure.Type: GrantFiled: January 29, 2009Date of Patent: July 1, 2014Inventor: Franco Beoni
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Patent number: 8764827Abstract: A test device for an ossicular prosthesis for implantation in the middle ear that includes a first fastening element, a second fastening element and a connecting element that connects the two fastening elements in a sound-conducting manner. Parts of the ossicular prosthesis are made of a material having memory effect and subjected to shape-altering thermal treatment at implantation. The test device also includes a device for determining an optimized power setting or an energy application site for preparing parts of the ossicular prosthesis to be subjected intraoperatively to thermal treatment using a prosthesis mock-up that is identical in design to the ossicular prosthesis in terms of material, geometric shape, and manufacturing method in the parts to be subjected intraoperatively to thermal treatment.Type: GrantFiled: February 16, 2011Date of Patent: July 1, 2014Assignee: Heinz Kurz GmbH MedizintechnikInventor: Uwe Steinhardt
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Patent number: 8758436Abstract: An expansible ear canal insert for treating TMJ disorders and headaches which acts directly on the TMJ and associated ligament and muscle structures to reduce stress and loads placed on the articulator disc located between the temporal bone and the mandible, as well as supportive muscles and ligaments near the TMJ. The insert is adapted to expand by application of body heat. In the expanded condition, the insert provides support to the TMJ and associated ligament and muscle structures.Type: GrantFiled: September 17, 2009Date of Patent: June 24, 2014Inventors: Lawrence G. Clayton, William Coole
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Patent number: 8741281Abstract: The specification discloses compositions and methods for treating a soft tissue defect of an individual.Type: GrantFiled: February 16, 2012Date of Patent: June 3, 2014Assignee: Allergan, Inc.Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Adam L. Collette, Rebecca L. Horan, Jingsong Chen, Gregory H. Altman, Wha Bin Im
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Patent number: 8721518Abstract: An implantable microphone for use in hearing systems includes a housing having a sidewall, a first membrane coupled to a top portion of the housing and configured to move in response to movement from an auditory ossicle, and a second membrane coupled to the sidewall such that an interior volume of the housing is divided into a first volume and a second volume. The second membrane has an opening that permits fluid to flow from the first volume to the second volume. The implantable microphone also includes a vibration sensor adjacent to the second membrane and configured to measure the movement of the second membrane and to convert the measurement into an electrical signal. The vibration sensor may include a piezoelectric sensor and/or a MEMS sensor.Type: GrantFiled: November 23, 2010Date of Patent: May 13, 2014Assignee: MED-EL Elektromedizinische Geraete GmbHInventors: Alexander Hellmuth, Thomas Zahnert, Gert Hofmann, Matthias Bornitz, Hannes Seidler, Karl-Bernd Hüttenbrink
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Patent number: 8715347Abstract: Described are methods of reshaping a cartilage structure. One such method comprises creating a virtual three dimensional image of the cartilage structure; manipulating the virtual three dimensional image of the cartilage structure so as to obtain a virtual three dimensional image of a desired final shape of the cartilage structure; creating a virtual prototype of a device to hold the cartilage structure in the desired final shape of the cartilage structure; manufacturing the device; lasing the cartilage structure; and fitting the manufactured device to the cartilage structure (e.g., ear).Type: GrantFiled: April 15, 2011Date of Patent: May 6, 2014Assignee: Chondrocyte, LLCInventors: Pascal Servell, Serge Mordon, Jack Savage
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Patent number: 8697057Abstract: The specification discloses compositions and methods for treating a soft tissue defect of an individual.Type: GrantFiled: February 16, 2012Date of Patent: April 15, 2014Assignee: Allergan, Inc.Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
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Patent number: 8697056Abstract: The present specification discloses compositions and methods of transplanting tissue useful for treating a soft tissue condition of an individual.Type: GrantFiled: July 29, 2011Date of Patent: April 15, 2014Assignee: Allergan, Inc.Inventors: Dennis E. Van Epps, Guang-Liang Jiang, Wha Bin Im
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Patent number: 8697059Abstract: The present specification discloses compositions and methods for use in breast augmentation procedures. The compositions include adipose tissue and compounds that upregulate both FGF-2 and VEGF, promote new blood vessel formation thereby reducing tissue volume loss and increasing survival rate of the adipose tissue when the composition is introduced into breast tissue.Type: GrantFiled: May 3, 2013Date of Patent: April 15, 2014Assignee: Allergan, Inc.Inventors: Dennis Van Epps, Guang-Liang Jiang, Wha Bin Im
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Publication number: 20140094910Abstract: A passive ossicular prosthesis includes a first and second fastening element for connection to the tympanic membrane. A connecting element connects the fastening elements in a sound-conducting manner. The connecting element includes a receiving part and an insertion part. The insertion part is inserted into a receiving opening of the receiving part. The receiving part encloses an end section of the insertion part in the manner of a clamp by way of two opposing, parallel legs disposed parallel to a shank axis of the connecting element. The legs have catch devices that fix the enclosed end section discrete spatial positions relative to the shank axis.Type: ApplicationFiled: October 3, 2012Publication date: April 3, 2014Inventors: Uwe Steinhardt, Thomas Lenarz, Axel Lang, Heinz Kurz
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Patent number: 8685090Abstract: An auditory ossicle prosthesis (10) with a sound transmitting prosthesis body (13) has first and second coupling elements (11, 12) provided at opposite ends. A stabilizer element (14) fixes the prosthesis on a level with the plane of the tympanic membrane and stabilizes the position of the prosthesis in the middle ear. A fixation part (14.2) anchors the Y-shaped stabilizer element at one or more places of the ear canal wall. The fixation part includes two hooked anchoring elements (16) that secure the fixation part in artificially drilled holes in the ear canal wall. The auditory ossicle prosthesis has a particularly simple and compact design and stays spatially fixed within very small variations in its initial position after implantation inside the middle ear cavity, providing effective protection against post-operative dislocation, tilting or tipping and without deteriorating sound transmission properties of the prosthesis.Type: GrantFiled: January 25, 2012Date of Patent: April 1, 2014Assignee: Heinz Kurz GmbH MedizintechnikInventors: Robert Vincent, Uwe Steinhardt
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Publication number: 20140088704Abstract: Feedthrough constructions comprise a housing with a feedthrough disposed within a housing opening, wherein the feedthrough is configured to facilitate passage of electrical signals through the housing. The feedthrough has a circumference specially configured to reduce the variation in compressive stress imposed onto the feedthrough by the housing to reduce crack development and/or propagation to thereby extend effective service life.Type: ApplicationFiled: September 21, 2012Publication date: March 27, 2014Inventors: Grahame Walling, Anthony Powell
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Publication number: 20140074238Abstract: Described here are self-expanding devices and methods of using and making them. The devices may be useful in a variety of locations within the body, for a number of different uses. In some variations, the devices have a first compressed configuration enabling low profile delivery through a delivery device, a second expanded configuration for apposition against tissue, and comprise either a single continuous filament or at least two non-intersecting filaments. In some variations, the device is formed into a shape having a series of peaks and valleys. At least one of the peaks and valleys may have a loop at then end thereof. At least a portion of these devices may be capable of biodegrading over a predetermined period of time, and the devices may be configured for drug delivery. Methods of treating one or more sinus cavities are also described here.Type: ApplicationFiled: November 15, 2013Publication date: March 13, 2014Applicant: Intersect ENT, Inc.Inventors: Anthony J. ABBATE, Bin HUANG, Gail M. ZALER, David C. GALE, Richard E. KAUFMAN
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Patent number: 8663673Abstract: The present invention relates to devices, articles, coatings, and methods for controlled active agent release and/or for providing a hemocompatible surface. More specifically, the present invention relates to copolymer compositions and devices, articles, and methods regarding the same for controlled active agent release. In an embodiment, the present invention includes a copolymer composition. The copolymer composition can include a copolymer and an active agent. In an embodiment, the copolymer includes an effective portion of a monomeric unit including a polar moiety. The active agent can be polar. The active agent can be charged. The active agent can be non-polar. In an embodiment, the copolymer composition includes a random copolymer. In an embodiment, the random copolymer includes butyl methacrylate-co-acrylamido-methyl-propane sulfonate copolymer, which can provide reduced platelet adhesion.Type: GrantFiled: July 26, 2006Date of Patent: March 4, 2014Assignee: Surmodics, Inc.Inventors: Timothy M. Kloke, Robert W. Hergenrother, Laurie R. Lawin
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Publication number: 20140039619Abstract: A rhinological implant for straightening the nasal septum is fastened on both sides of a septum (S), separating left and right sides of a nasal cavity of a human nose, on the outer surface of the septum (S), in the left and the right sides of the nasal cavity. Before implantation, the implant is folded up from an initially flat blank into an implantable three-dimensional shape. The implant has a central back section which in an implanted state wraps around the free lower edge of the septum. Two side sections are provided on either side of the central back section to extend symmetrically with respect to the central back section. In the implanted state, the two side sections bear via the entire surface against the two diametrically opposed outer surfaces of the septum (S).Type: ApplicationFiled: July 31, 2013Publication date: February 6, 2014Applicant: HEINZ KURZ GMBH MEDIZINTECHNIKInventors: Daniel Felix ÀWENGEN, Uwe Steinhardt
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Patent number: 8641760Abstract: A system is provided for stabilized total ossicular replacement in a middle ear having an intact stapes with a capitulum and a footplate. The system includes an ossicular replacement prosthesis including with elongate shaft and a head coupled to the shaft, and a stabilizer that couples the prosthesis to the stapes. The stabilizer has a first portion with a first opening and a second portion with a second opening, said first opening sized to stably engage the shaft of the prosthesis, and said second opening sized to stably engage the capitulum. When the shaft and capitulum are engaged they are retained in an side-by side configuration. The stabilizer may be constructed of an elastic polymer, an elastic metal alloy, a plastic material or a shape memory material.Type: GrantFiled: May 6, 2011Date of Patent: February 4, 2014Assignee: EnteroptyxInventors: Richard W. Mendius, Anthony D. Prescott, Patrick Ireland
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Patent number: 8630721Abstract: An electrode array which is able to be inserted to a desired depth within the cochlea to provide useful percepts for the recipient which will also preferably not cause damage to the sensitive structures of the cochlea. The electrode array is insertable through an opening in the cochlea and into at least the basal region of the cochlea and comprises an elongate carrier having a proximal end, a distal end, and a plurality of electrodes supported by the carrier at respective spaced locations thereon in a region between the proximal end and the distal end. A stabilising collar extends outwardly from the elongate carrier at or adjacent a proximal end thereof and has an abutment surface adapted to abut a portion of the cochlea surface around the cochleostomy and at least substantially prevent movement of the carrier following completion of insertion of the array into the cochlea.Type: GrantFiled: January 26, 2012Date of Patent: January 14, 2014Assignee: The University of IowaInventor: Bruce J. Gantz
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Publication number: 20140012282Abstract: A tympanostomy tube for insertion into and residence in a tympanic membrane of a mammal, is disclosed. The tympanostomy tube includes a body including a first end portion, a second end portion, a central portion dispensed between the first and second end portions. An axially extending passageway has a first open end disposed adjacent the first end portion, and a second open end disposed adjacent the second end portion, and an axis extending between the first open end and second open end. The first end portion includes a relatively enlarged diameter, generally radially extending flange. The central portion includes a reduced diameter portion sized for extending through and residing in tissue of the tympanic membrane. The second end portion includes a relatively enlarged diameter second flange disposed adjacent the second end portion.Type: ApplicationFiled: February 12, 2013Publication date: January 9, 2014Inventor: MICHAEL H. FRITSCH
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Publication number: 20130345809Abstract: A suction activated instrumentation system for use in implanting an ossicular prosthesis into the middle ear includes a suction handpiece and a vacuum source. A removable suction tip is coupled to the handpiece for engaging an ossicular prosthesis. The suction tip includes a distal portion with an elongate slot opening at an end face, and two arms defined at the end face. When suction is applied through the suction tip, the prosthesis is drawn against the end face and retained between the arms. In the event the prosthesis is inadvertently contacted during implantation, the suction tip provides for self-correction, causing a prosthesis to re-orient into the prior intended configuration.Type: ApplicationFiled: June 20, 2012Publication date: December 26, 2013Inventors: Anthony D. Prescott, Murray Beard
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Publication number: 20130325121Abstract: Medical devices with a plastic albumin body with a defined three dimensional shape that are particularly suitable for pressure equalization tubes. The plastic albumin body can be a unitary substantially monolithic body of albumin. The plastic albumin body has an antibacterial property such that it is resistant to bacterial adhesions and/or bacterial biofilm formation thereon. Methods and processes are described for forming a consolidated protein-based coating on an implant, and coated implants produced therefrom, with improved biocompatibility, nonthrombogenity and antimicrobiality that are suitable for various medical implants and drug delivery devices, such as bone implants, catheters, cannuale, guide wires, stents, shunts, vascular grafts, heart valves, heart and ventricular assist devices, oxygenators, dialyzers, medical devices, and other substrates, such as furniture, keyboards, etc.Type: ApplicationFiled: May 30, 2013Publication date: December 5, 2013Applicant: Clemson UniversityInventors: Benjamin R. Whatley, Xuejun Wen, Igor Luzinov, Suraj Sharma
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Patent number: 8579973Abstract: A device stenting the Eustachian tube is inserted through the nasopharynx and provides enhanced ventilation and drainage to the middle ear. Also provided is a method for inserting the device into the Eustachian tube and through the isthmus of a human subject.Type: GrantFiled: March 30, 2012Date of Patent: November 12, 2013Inventor: Galit Avior
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Publication number: 20130289723Abstract: The purpose of the present invention is to obtain an alternative to a substitute of the mucosa in the middle ear which is engrafted on the surface of the bone in the middle ear, hyperplasia of the granulation tissue and the bone and the development of the fibroblast cell sir the middle ear are suppressed, and to obtain a middle ear mucosa-like cell sheet retaining cilia in the surface layer, comprising culturing nasal epithelium cells on a cell culture substrate coated with a polymer whose hydration force changes within a temperature range of 0 to 80 ° C., wherein the cells are cultured within a temperature range where the hydration force of the polymer is weak, and then changing the temperature to a temperature at which the hydration force is strong to recover the cultured cell sheet.Type: ApplicationFiled: September 15, 2011Publication date: October 31, 2013Applicants: The Jikei University, Tokyo Women's Medical UniversityInventors: Takanori Hama, Hiromi Kojima, Hiroshi Moriyama, Masayuki Yamato, Teruo Okano
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Publication number: 20130274877Abstract: A prosthesis for insertion in an ear to reduce pain resulting from TMJ disorders. The ear insert has a predefined shape conforming to the shape of the ear canal when the jaw is in an open position. The ear insert supports the TMJ and associated secondary musculature to reduce strain in the TMJ area, including the muscles, ligaments, nerves, and the temporo-mandibular joint itself. The insert is hollow in the inside to permit hearing and is made of a rigid material which retains the shape of the ear canal. A scalloped indenture extends across a surface of the ear insert positioned behind the tragus.Type: ApplicationFiled: June 7, 2013Publication date: October 17, 2013Inventor: Lawrence G. Clayton
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Publication number: 20130226297Abstract: An exemplary method includes a sound processor 1) mapping an analysis channel associated with a frequency band to a stimulation channel that comprises at least three electrodes communicatively coupled to an auditory prosthesis associated with a patient, 2) identifying a spectral peak included in an audio signal presented to the patient, the spectral peak having a peak frequency included in the frequency band, and 3) directing the auditory prosthesis to apply electrical stimulation representative of the spectral peak to a stimulation site associated with the peak frequency by simultaneously stimulating at least two of the at least three electrodes at substantially fifty percent or less of their respective most comfortable current levels (M levels) in accordance with a multi-monopolar current steering strategy. Corresponding methods and systems are also disclosed.Type: ApplicationFiled: October 28, 2011Publication date: August 29, 2013Applicant: ADVANCED BIONICS AGInventors: Lakshmi N. Mishra, Leonid M. Litvak, Manohar Joshi
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Patent number: 8518112Abstract: A device for adjusting and fixing relative position between an actuator end piece of an active hearing implant and an element of the ossicular chain or a coupling part to the human inner ear has a connecting element with a first coupling element for coupling to the actuator end piece, a second coupling element, and a shaft-shaped middle part, and the first coupling element geometrically encompasses the actuator end piece with two opposing parallel arms each having a pattern element to fix the encompassed actuator end piece in selectable discrete axial positions in a direction parallel to an axis of the shaft-shaped middle part, for variable-length adaptation and fixing of the actuator end piece relative to the first coupling element in a direction transverse to the axis.Type: GrantFiled: September 21, 2011Date of Patent: August 27, 2013Assignee: Heinz Kurz GmbH MedizintechnikInventors: Thomas Lenarz, Uwe Steinhardt, Heinz Kurz
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Patent number: 8506628Abstract: An ossicular prosthesis includes a proximal end provided with an open conically helical coil for engaging a first ossicular structure, and a distal bell head, piston, or shoe for engaging a second ossicular structure. A connecting element extends therebetween the two to hold the helical coil structure which engages the second ossicular engagement structure in a preferably fixed relationship. The helical coil defines a plurality of spaced apart adjacent windings, with open spaces between the windings. Each adjacent winding decreases in diameter from the proximal to distal end. The windings of the coil may be adjusted relative to each other in length or angle to fit the anatomy. In accord with a one method of use, the helical coil and optionally other portions of the prosthesis function as an armature or endoskeleton. A cement may be provided over the prosthesis to reconstruct the eroded or missing ossicles.Type: GrantFiled: November 14, 2011Date of Patent: August 13, 2013Assignee: EnteroptyxInventor: Eric M. Kraus
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Patent number: 8500808Abstract: Provided is an artificial eardrum using silk protein and a method of fabricating the same. The artificial eardrum is fabricated in the form of a silk membrane by desalinating and drying silk protein (or silk fibroin) or a silk protein complex solution obtained after removal of sericin from a silkworm cocoon or silk fiber. Thus, regeneration of an eardrum perforated due to disease or a sudden accident is stimulated, a boundary of the regenerated eardrum is clean and biocompatibility and transparency are increased. In addition, the artificial eardrum may be fabricated using the silk protein or silk protein complex solution obtained from a silkworm cocoon alone or mixed with collagen, alginic acid, PEG or pluronic 127.Type: GrantFiled: June 29, 2009Date of Patent: August 6, 2013Assignees: Republic of Korea represented by Rural Development Administration, Industry Academic Cooperation Foundation, Hallym UniversityInventors: Hae Yong Kweon, Kwang Gill Lee, Seok Woo Kang, Joo Hong Yeo, You Young Jo, Soon Ok Woo, Sang-Mi Han, Chan Hum Park, Jin Kim, Chun Hwoi Kim
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Patent number: 8491510Abstract: A system and method for correcting misshaped ears using a base section defining an opening dimensioned to accommodate the passage of the ear through the opening and a top section releasably engageable with the base section defining a compartment therebetween. A first stint can be arranged on an anterior surface of the base section to maintain a desired anatomic shape of the ear essentially in an area of the antihelix and the superior limb of the triangular fossa. A second stint can be placed in an area of the scapha of the ear to maintain a desired contour of the scaphal area. A conchal stint can be placed in the concha to maintain a desired anatomic shape of the concha. The top section can be engaged to maintain a desired amount of stabilizing pressure on the ear, the first stint, the second stint, and conchal stint.Type: GrantFiled: February 10, 2012Date of Patent: July 23, 2013Assignee: Beacon Medical LimitedInventors: Henry Stephenson Byrd, C. Kenneth French, Garrett Barker
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Publication number: 20130184817Abstract: The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-activated cation channels to specific cells or defined cell populations. In particular the invention provides millisecond-timescale temporal control of cation channels using moderate light intensities in cells, cell lines, transgenic animals, and humans. The invention provides for optically generating electrical spikes in nerve cells and other excitable cells useful for driving neuronal networks, drug screening, and therapy.Type: ApplicationFiled: July 23, 2012Publication date: July 18, 2013Inventors: Edward S. Boyden, Karl Deisseroth
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Publication number: 20130178937Abstract: A method and apparatus for treating a nasal valve condition including surgically forming an access path to create a pocket on a side of the patient's nose. The pocket is positioned between a soft tissue layer and opposing surfaces of upper and lower cartilages of the nose. The pocket spans a junction between the upper and lower cartilages. An implant is placed through the access path into the pocket with a length oriented to span the junction. A delivery system for placement of the implant includes a surgical tool for forming the access path and for delivering the implant into the access path.Type: ApplicationFiled: March 1, 2013Publication date: July 11, 2013Applicant: MEDTRONIC XOMED, INC.Inventor: MEDTRONIC XOMED, INC.
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Patent number: 8480737Abstract: Novel bioabsorbable, columellar strut implants are disclosed. The struts are useful in rhinoplasty and nasal reconstruction surgical procedures. The devices have opposed lateral sides connected to a spine member to form a tissue-receiving channel.Type: GrantFiled: September 27, 2010Date of Patent: July 9, 2013Assignee: Ethicon, Inc.Inventors: Krasimira Hristov, Gavin Chen, Jianxin Guo, James A. Matrunich
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Publication number: 20130172996Abstract: In one embodiment, a method of treating hearing loss in a patient, comprises: creating a first channel in osseous tissue at or immediately adjacent to the promontory of the patient; creating a second channel through the first channel to the scala tympani or the scala vestibuli; and implanting a hearing device in the first channel, the hearing device being in fluid communication with cochlear fluid through the second channel, the hearing device being adapted to drive cochlear fluid to activate auditory receptor cells in the cochlea of the patient.Type: ApplicationFiled: October 10, 2012Publication date: July 4, 2013Inventor: Terry Daglow
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Patent number: RE44580Abstract: A scaffold for reshaping an ear or a nose, the scaffold being configured to be i) attached to the cartilaginous portion of an ear or ii) attached to the cartilaginous portion of a nose, wherein the scaffold is formed at least in part from a shape-memory material and/or a plastic material and is capable of transforming from a first configuration to a second, pre-programmed configuration.Type: GrantFiled: August 17, 2012Date of Patent: November 5, 2013Assignee: West Hertfordshire Hospitals NHS TrustInventors: Norbert Kang, David Gavin