Abstract: A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions.

Abstract: Provided are an artificial cornea having sufficient strength and optical properties, in which deviation or infection of the artificial cornea is restrained, and a method for manufacturing the artificial cornea. According to the present invention, the method for manufacturing the artificial cornea includes a nonwoven fabric preparation step of preparing a nonwoven fabric formed therein with a through-hole, and a gel arrangement step of arranging an aqueous polymer gel to cover the through-hole.

Abstract: Reversibly deformable corneal implants for replacing excised corneal tissue, the implants including an optical portion and an anchoring portion having different mechanical properties from each other.

Abstract: A mask is provided that is configured to increase the depth of focus of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a portion surrounding at least a portion of the aperture. The portion may be configured to be substantially opaque to visible electromagnetic radiation and be substantially transparent to electromagnetic radiation transmitted from an ocular examination device (e.g., substantially transparent to at least some non-visible electromagnetic radiation with a wavelength between about 750 nm and about 1500 nm).

Abstract: A system includes a scleral prosthesis and an insert. The scleral prosthesis includes an elongated body having a first free end and a second free end opposite the first end. A maximum width of the body at each end is wider than a maximum width of the body between the ends. The body includes multiple first portions that form the first end of the body and a part of the body between the ends. The first portions are separated lengthwise along a substantial portion of a total length of the body. The first portions are biased so that they maintain separation from one another without external interference but are configured to be pushed towards each other. The insert is configured to be placed between the first portions to maintain a separation of the first portions. The body and/or the insert could be formed using one or more magnetic materials.

Abstract: The present disclosure provides an artificial iris prepared by forming a ring-shaped hydrophilic region on a biocompatible substrate, coating a curable material thereon and then coating a photoreactive material mimicking the iris frills through optical irradiation. The artificial iris may be implemented into the real human eye and is capable of regulating the intensity of the light reaching the retina through the pupil depending on the intensity of ambient light.

Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials contain a hydrophilic side-chain macromer for glistening resistance.

Abstract: The present invention relates to a deformable object to be implanted into a surgical site (exemplified by but not limited to a cornea lenticule, e.g., that could be native corneal tissue or a synthetic or biosynthetic construct), surgical instrumentation for altering the curvature and arc length of the deformable object to be implanted (e.g. corneal lenticule), as well as methods for introduction of the deformable object into the specifically prepared wound bed and for introduction of the deformable object.

Abstract: An apparatus, system and method for constricting a cornea of a human eye are disclosed. A control device external to the subject eye, such as an induction generator, may be configured to create a stimulus, such as a magnetic field, for an implanted ring that, when stimulated, may change the curvature, and thus the dioptric power, of the eye, thereby approximating natural accommodation.

Abstract: A description has been provided herein of an intrastromal segment especially designed for use as a prosthesis inside the corneal tunnel of patients suffering from keratoconus. The segment consists of a lengthened body of variable dimensions in the form of an arc with noticeably rounded ends, devoid of any communicating orifice, and endowed with a transverse section that may be triangular, trapezoidal, hexagonal or oval, with at least three marks connecting to the narrowest side for which two ends aid the safe handling of the segment and the mid-section mark serves as a positional reference point. The segment will be connected to a disposable guide track along which it moves and from which it is pushed into the implantation position.

Abstract: A system for measuring the size of a capsular bag of an eye of a subject includes a size indicator and a sizing gauge. The size indicator is configured for insertion into a capsular bag and includes a peripheral portion and a pair of arms. The peripheral portion is configured to engage the capsular bag. Each of the arms has a proximal end and a distal end, the arms being joined to one another at the proximal ends. The peripheral portion is joined to the distal ends of the arms. The arms form an angle that depends on a size of the capsular bag into which the size indicator is placed.

Abstract: A device has been described here which is used as a means of implanting an intrastromal prosthesis, consisting of a segment or ring, on the inside of the patient's corneal tunnel. The implanting device eliminates the need to use conventional forceps and includes for this purpose an injector with a support track for the implant segment, attached to a ring carrier piece coupled to the first end of a cylinder base or tunnel. A Delhom apparatus, activated by rotation, includes a central arm with an impeller tip for the insertion of the segment, and a block cover coupled to the opposite end of the cylinder base or tunnel includes a rod that extends along its length, finished in a tip positionable on the inside of the track against the back end of the segment, and a recess to accommodate the carrier arm of the impeller tip and the ring-holder clamp.

Abstract: The present invention relates to an intrastromal corneal device for reshaping the curvature of the cornea comprising a substantially circular structure having a convex surface provided with openings for biological exchange between the layers of the cornea, said substantially circular structure comprising the shape of a circular segment or of a spherical/aspheric cap provided or not with a central opening. Said device further comprises means for promoting the reshaping of the cornea, so that it assumes a curvature closer to the intended curvature, thus providing a significant reduction of visual disturbances caused by corneal ectatic conditions such as keratoconus.

Abstract: An accommodating artificial ocular lens (AAOL) device including a lens optic portion connected to a pleated lens haptic portion to provide accommodation of vision of the eye.

Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials contain a functionalized alkylphenol ethoxylate to reduce glistenings.

Abstract: A mask configured to be implanted in a cornea of a patient to increase the depth of focus of the patient includes an anterior surface, a posterior surface, and a plurality of holes. The anterior surface is configured to reside adjacent a first corneal layer. The posterior surface is configured to reside adjacent a second corneal layer. The plurality of holes extends at least partially between the anterior surface and the posterior surface. The holes of the plurality of holes are configured to substantially eliminate visible diffraction patterns.

Abstract: DMEK surgery is performed using a carrier mat made of a polymeric material having elastic memory and a hydrophilic surface, for supporting the descemet's membrane and transporting it to an insertion capsule.

Abstract: A pre-formed intrastromal corneal insert for use in treating Keratoconus and similar dystrophies and methods of using the same. An intrastromal insert of the present invention comprises a biocompatible polymer and may be used to adjust corneal curvature, thereby correcting vision abnormalities caused by disease or other surgical procedures. The insert may be comprised of a circular or semi-circular ring shape or a portion of a ring, or “arc”, encircling the anterior cornea within the frontal circumference of the cornea. The insert may be used in multiples to form complete arcs or to form constructs of varying thicknesses. The insert of the present invention possesses a cross section that results in a low scattering level of light.

Abstract: Annular cornea implant for inserting into a cornea pocket of the human eye via a narrow, tunnel-shaped access, with the end shape of the cornea implant depending on the shortsightedness or astigmatism to be corrected. To enable the cornea implant to be implanted in the cornea pocket in a simple manner and in an optimum position, the implant has a shape memory which is impressed on the basis of the geometry and/or material of the implant, and is designed in such a way that the deformability from a starting shape enables the insertion of the cornea implant into the cornea pocket via the narrow access, and the cornea implant has an adjustment force in the end shape thereof, which enables an essentially independent unfolding of the cornea implant in the cornea pocket.

Abstract: Corneal implant to be introduced into the optical center (Z) of the cornea of the human eye for the purpose of correcting impaired vision, in particular presbyopia, or presbyopia in combination with hypermetropia or myopia. To propose a corneal implant which is suited for introduction into the optical center (Z) of the human eye, and which may be applied for correcting presbyopia on its own or in combination with hypermetropia or myopia, the effective thickness (d) of the corneal implant (2), measured in the direction of the optical axis (5) of the eye, must be larger than 50 ?m and the maximum width (b), measured in a plane perpendicular to the direction of thickness, must be less than 1 mm, the corneal implant (2) having no imaging function in relation to the human eye.

Abstract: A method and apparatus for increasing the depth of focus of the human eye is comprised of a lens body, an optic in the lens body configured to produce light interference, and a pinhole-like optical aperture substantially in the center of the optic. The optic may be configured to produce light scattering or composed of a light reflective material. Alternatively, the optic may increase the depth of focus via a combination of light interference, light scattering, light reflection and/or light absorption. The optic may also be configured as a series of concentric circles, a weave, a pattern of particles, or a pattern of curvatures. One method involves screening a patient for an ophthalmic lens using a pinhole screening device in the lens to increase the patient's depth of focus. Another method comprises surgically implanting a mask in the patient's eye to increase the depth of focus.

Abstract: A ring that can maintain a pupil in an extended position during an ophthalmic procedure. The ring has a plurality of loops that capture iris tissue. The ring is configured to extend the pupil when iris tissue is inserted into each loop. An ophthalmic procedure such as phacoemulsification can then be performed on the patient. The ring has a center opening that provides a wide view of the ocular chamber during the procedure.

Abstract: The invention is a surgical instrument (1) used in ophthalmology, which allows a penetrating or lamellar cornea transplant without the use of suture. It comprises a set of arc segments interconnected by a small diameter polypropylene wire (2), which goes through the internal body structure of each segment. The first arc segment (3), also called the segment guide, is an arc of 160-330 degrees with a circular cross-section and a rounded edge. The second arc segment (4), also called the main segment, is an arc of 270-360 degrees, and has a horizontal or oblique cross-section tangential to the surface of the cornea, or a circular cross-section. The third arc segment (5), also called the secondary segment, has a thickness or cross-section greater than that of the main segment.

Abstract: Disclosed are soft, high refractive index device materials having improved strength. The materials contain a polystyrene macromer.

Abstract: Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. A flexible ring or ring portion may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag, for example, after extraction of a natural lens from the capsular bag. The ring or ring portion is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring or ring portion includes a central component that changes shape and/or angle as the ring or ring portion is compressed. The shape change is generally correlated to the size of the capsular bag and may be visually measured through the cornea, the measurement being generally independent of corneal magnification. The measurement may be used to determine or calculate information about the capsular bag such as its size, elasticity, accommodative range, and so forth.

Abstract: A system for measuring the size of a capsular bag of an eye of a subject includes a size indicator and a sizing gauge. The size indicator is configured for insertion into a capsular bag and includes a peripheral portion and a pair of arms. The peripheral portion is configured to engage the capsular bag. Each of the arms has a proximal end and a distal end, the arms being joined to one another at the proximal ends. The peripheral portion is joined to the distal ends of the arms. The arms form an angle that depends on a size of the capsular bag into which the size indicator is placed. The sizing gauge has a body having a front surface, along with first and second features disposed along or behind the front surface. The features are configured to correspond to an angle that is within a predetermined range of angles of the arms of the size indicator when the size indicator is placed within a capsular bag.

Abstract: Annular cornea implant for inserting into a cornea pocket of the human eye via a narrow, tunnel-shaped access, with the end shape of the cornea implant depending on the shortsightedness or astigmatism to be corrected. To enable the cornea implant to be implanted in the cornea pocket in a simple manner and in an optimum position, the implant has a shape memory which is impressed on the basis of the geometry and/or material of the implant, and is designed in such a way that the deformability from a starting shape enables the insertion of the cornea implant into the cornea pocket via the narrow access, and the cornea implant has an adjustment force in the end shape thereof, which enables an essentially independent unfolding of the cornea implant in the cornea pocket.

Abstract: The present invention includes an ophthalmic device and system of mounting for correcting hyperopia and presbyopia. The present invention includes a limbus ring mountable in an encircling relation to a central optic zone of a cornea on a limbus annulus surrounding the cornea. In the limbus ring defines a substantially annular toroid defining a first average diameter that is selectable and has a hydrophilic coating disposed thereon. The inner radius of the limbus ring is selectable such that, upon mounting on the limbus annulus, the limbus ring causes the limbus annulus to contract thereby causing the curvature of the cornea and the eye length to increase. The mounting system of the present invention is adapted to receive a limbus ring and further adapted to selectively place the limbus ring on a limbus annulus.

Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials contain a functionalized alkyl ethoxylate to reduce glistenings.

Abstract: Annular cornea implant for inserting into a cornea pocket of the human eye via a narrow, tunnel-shaped access, with the end shape of the cornea implant depending on the shortsightedness or astigmatism to be corrected. The aim of the invention is to enable the cornea implant to be implanted in the cornea pocket in a simple manner and in an optimum position. To this end, the implant has a shape memory which is impressed on the basis of the geometry and/or material of the implant, and is designed in such a way that the deformability from a starting shape enables the insertion of the cornea implant into the cornea pocket via the narrow access, and the cornea implant has an adjustment force in the end shape thereof, which enables an essentially independent unfolding of the cornea implant in the cornea pocket.

Abstract: Disclosed are soft, high refractive index, acrylic device materials. The materials contain a hydrophilic side-chain macromer for glistening resistance.

Abstract: A method is provided for increasing the outflow of fluid through Schlemm's canal that is useful for treatment of glaucoma. The implant is placed in Schlemm's canal by use of a flexible delivery instrument attached to the implant. The instrument and implant are positioned within the canal, the implant is released and the distal and proximal ends of the implant are connected to apply sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability. In another embodiment a delivery instrument attached to the implant is positioned in the canal securing one of the distal or proximal ends of the implant within the canal. The implant provides sufficient axial tensioning force on the inner wall of the canal to increase fluid permeability of the inner wall of the canal. The other of the distal or proximal ends may be secured to maintain the tensioning force on the inner wall of the canal.

Abstract: A system for measuring the size of a capsular bag of an eye of a subject includes a size indicator and a sizing gauge. The size indicator is configured for insertion into a capsular bag and includes a peripheral portion and a pair of arms. The peripheral portion is configured to engage the capsular bag. Each of the arms has a proximal end and a distal end, the arms being joined to one another at the proximal ends. The peripheral portion is joined to the distal ends of the arms. The arms form an angle that depends on a size of the capsular bag into which the size indicator is placed. The sizing gauge has a body having a front surface, along with first and second features disposed along or behind the front surface. The features are configured to correspond to an angle that is within a predetermined range of angles of the arms of the size indicator when the size indicator is placed within a capsular bag.

Abstract: Implantation of an accommodating intraocular lens in an eye may require the accurate measurement of the size, circumference, or diameter of the capsular bag of the eye. After the natural crystalline lens has been surgically removed, a flexible ring may be temporarily or permanently inserted into the capsular bag for measuring the circumference of the capsular bag. The ring is generally compressible to fit through a surgical incision, then expands to fill the capsular bag along an equatorial region. The ring has a central component that changes shape as the ring is compressed. The shape change is generally correlated to the size of the capsular bag and may be measured visually or with a camera through the cornea, the measurement being generally independent of corneal magnification.

Abstract: The invention relates to a support element to compensate for deformations of the cornea H of an eye, having an annular support body 2 in one or more pieces, which makes it possible to compensate for keratoconus with minimised stress on the cornea of the eye being treated. This is achieved according to the invention in that the support body 2 has a cross section which is flattened on one side and otherwise rounded, so that a circumferential front-side flattening 6 is formed on it.

Abstract: Devices, systems, and methods useful in treating an eye are provided herein. Certain embodiments of the devices, systems, and methods may be particularly suitable in maintaining separation of an anterior capsule and a posterior capsule of an evacuated lens capsule of an eye. Certain embodiments of the devices, systems, and methods may be particularly suitable for reducing scarring in the visual field of an eye having a capsulorhexis, among other things.

Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: An in-phase intracorneal lens system that prevents substantial movement between connected lenses to provide high resolution of the eye. A first lens is adapted to be positioned on a surface of a cornea. A second lens has a substantially ring-shaped configuration and is substantially concentric with the first lens. At least one first bridge member extends from the first lens to the second lens to couple the first lens to the second lens to prevent substantial movement between the first and second lenses.

Abstract: Implants configured for corneal implantation are disclosed that have a light transmitting portion and a light-blocking portion disposed about the periphery of the implant. The implant can be an elongate member, such as a split or continuous ring, that can be implanted in the cornea to alter the refractive properties of the cornea by altering the curvature of the anterior surface of the cornea, thereby providing corrective refraction. The light-blocking portion can reduce edge effects, which may be visible or distracting to the patient.

Abstract: The present invention includes an ophthalmic device and system of mounting for correcting hyperopia and presbyopia. The present invention includes a limbus ring mountable in an encircling relation to a central optic zone of a cornea on a limbus annulus surrounding the cornea. In the limbus ring defines a substantially annular toroid defining a first average diameter that is selectable and has a hydrophilic coating disposed thereon. The inner radius of the limbus ring is selectable such that, upon mounting on the limbus annulus, the limbus ring causes the limbus annulus to contract thereby causing the curvature of the cornea and the eye length to increase. The mounting system of the present invention is adapted to receive a limbus ring and further adapted to selectively place the limbus ring on a limbus annulus.

Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: Disclosed are soft, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer and a tack-reducing macromer additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.

Abstract: This invention is a hybrid intrastromal corneal ring (“ICR”) comprising at least one outer layer of a physiologically compatible polymer having a low modulus of elasticity, which polymer may be hydratable and may be hydrophilic. The inner portion of the ICR may be hollow or may contain one or more physiologically compatible polymers.

Abstract: A system adapted to modify refractivity of a cornea of an eye, including a first component, and adapted to be implanted at a first depth in the cornea. A second component, separate from the first component, is adapted to be implanted at a second depth in the cornea at a position relative to the first component, such that an axis passing through the eye parallel to the optical axis passes through the second component without passing through the first component. The second depth is closer to the front surface of the cornea than is the first depth.

Abstract: An in-phase intracorneal lens system that prevents substantial movement between connected lenses to provide high resolution of the eye. A first lens is adapted to be positioned on a surface of a cornea. A second lens has a substantially ring-shaped configuration and is substantially concentric with the first lens. At least one first bridge member extends from the first lens to the second lens to couple the first lens to the second lens to prevent substantial movement between the first and second lenses.

Abstract: An implantable keratoprosthesis having a central lenticule and a peripheral annulus of corneal tissue. The keratoprosthesis includes a transparent polymeric lenticule having an elongated stem with a generally cylindrical outer surface and a central axis. On one end thereof, the stem carries a dome having a peripheral skirt extending outwardly from the axis beyond the cylindrical surface of the stem. An annulus of corneal tissue has a central bore within which the stem is received, the peripheral skirt contacting and overlying a portion of the corneal annulus adjacent the bore. A portion of the annulus extends outwardly beyond the peripheral skirt for attachment to a surgically prepared cornea. A ring of polymeric material is received over the stem to capture between the ring and the skirt the corneal annulus.

Abstract: A device for helping to correct imperfections of a cornea includes a molding lens. The molding lens includes an external surface having a concave shape to correspond to the desired shape of the cornea. Heating and cooling elements are located with the molding lens to control the temperature the molding lens, and thus to control the temperature of a substance located on the molding lens.

Abstract: A bio-compatible corneal ring for myopic correction and accommodation for presbyopia. The corneal ring is made from a bio-compatible material with a lens body having an inner and outer circular edge. The inner circular edge forms an opening in the lens body. The posterior surface of the lens body has a uniform radii of curvature between the inner and outer circular edges. The anterior surface has two radii of curvatures providing for correction of myopia. The first radii of curvature extends from near the outer circular edge to a junction point before the inner circular edge. The second radii of curvature extends from the junction point and continues to the inner circular edge. The inner and outer circular edges have a thickness of less than about 0.020 mm, but preferably are about 0.010 mm or less.

Abstract: An ophthalmological implant including a layer of pharmaceutical agent and an overlying layer of a bioerodible material, a biodegradable material a bioavailable material or a mixture thereof.

Abstract: A method for correcting vision of an eye, including the steps of separating a portion of the cornea to form first and second internal surfaces in the cornea, and then placing at least one microscopic lens in between the first and second internal surfaces in the cornea, so that the external surface of the cornea is not substantially displaced. In a preferred embodiment, the microscopic lenses can be placed in concentric circles around the main optical axis so that the lenses form multifocal or bifocal vision.