Abstract: The present invention relates generally to the restoration or improvement of the quality of human vision and, more particularly to a self-adapting system and method for achieving automatic sharp vision by the human eye of objects for instance at distances between 25 cm and more than 10 meters away. The invention can be situated in at least four technological domains: 1. ophthalmology, in particular the implantation of intraocular lenses. 2. Non-contact biometric signal recording and processing. 3. Electro-optic control of refractive lens power. 4. Wireless energy transfer.

Abstract: Described are ocular devices such as intraocular lens preferably made of an organic polymeric material and an ultraviolet light absorber coated with a polarizing polymer component adjacent the edge thereof. A typical polarizing component is polyvinyl alcohol doped with iodine (PVA/I2). The ocular device with an added polarizing component is capable of absorbing light parallel to the axis of the polymer chain, while transmitting light that is perpendicular to the axis of the polymer chains. The polarizing component will reduce polarized light radiating off of horizontal surfaces; therefore, the film will improve vision through the device by reducing glare from light sources.

Abstract: A method and apparatus for increasing the depth of focus of the human eye is comprised of a lens body, an optic in the lens body configured to produce light interference, and a pinhole-like optical aperture substantially in the center of the optic. The optic may be configured to produce light scattering or composed of a light reflective material. Alternatively, the optic may increase the depth of focus via a combination of light interference, light scattering, light reflection and/or light absorption. The optic may also be configured as a series of concentric circles, a weave, a pattern of particles, or a pattern of curvatures. One method involves screening a patient for an ophthalmic lens using a pinhole screening device in the lens to increase the patient's depth of focus. Another method comprises surgically implanting a mask in the patient's eye to increase the depth of focus.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: Intraocular lenses are provided having a visible-light selective transmissive zone defined therein. The visible light-selective transmissive zone can be located near the lens center and designed to reduce the transmission of any wave-length of visible light specifically light in the blue light region having wavelength between approximately 400? to 550?. In one embodiment he IOLs are made from acrylates and the light absorbing compound is a yellow dye.

Abstract: An improved intraocular lens, for example, an accommodating intraocular lens including a lens optic or lens optic portion provided with a light window.

Abstract: An intraocular lens for insertion into a capsular bag in order to focus incoming light toward a retina and process for manufacturing thereof along with concomitant reduced glare and improved vision provides for a center lens portion of a lens for focusing incoming light toward the retina and the surrounding lens portion for mounting the lens within the capsular bag. A surface roughness disposed on the surrounding lens portion is provided for reducing the glare due to non-focused light directed toward the retina from the intraocular lens with the roughness having a roughness level of between about Ra 45 and about Ra 350.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. 2. In one embodiment the ophthalmic devices are made from acrylates and the light absorbing compound is an Eastman Yellow 035 MA dye.

Abstract: Embodiments of the present invention relate to an electro-active element having a dynamic aperture. The electro-active element provides increased depth of field and may be used in a non-focusing ophthalmic device that that is spaced apart from but in optical communication with an intraocular lens, a corneal inlay, a corneal onlay, a contact lens, or a spectacle lens that provide an optical power. The electro-active element provides increased depth of field and may also be used in a focusing or non-focusing device such as an intraocular optic, an intraocular lens, a corneal inlay, a corneal onlay, or a contact lens which may or may not have an optical power. By changing the diameter of dynamic aperture either increased depth of field or increased light reaching the retina may be achieved.

Abstract: The present invention relates to ophthalmic and non-ophthalmic systems with blue light filtering and Yellowness Index ranges. UV and IR filtering are also included. Industrial applications are also outlined in the invention.

Abstract: Intraocular lenses are provided having a visible-light selective transmissive zone defined therein. The visible light-selective transmissive zone can be located near the lens center and designed to reduce the transmission of any wave-length of visible light specifically light in the blue light region having wavelength between approximately 400 ? to 550 ?. In one embodiment he IOLs are made from acrylates and the light absorbing compound is a yellow dye.

Abstract: A method for causing visual images on the foveas of a patient to be differentially displaced from their default position by determining an optimal amount of displacement for each eye to maximize visual acuity while maintaining binocular vision, and fabricating lenses to achieve the determined differential displacements by use of two prisms of different dioptric strength. Optical devices, including eyeglasses and contact lenses, displace the images on the foveas of a patient by an amount sufficient to mitigate problems caused by non-fully functional foveas.

Abstract: Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. 2. In one embodiment the ophthalmic devices are made from acrylates and the light absorbing compound is an Eastman Yellow 035 MA dye.

Abstract: Intraocular lenses are provided having a visible-light selective transmissive zone defined therein. The visible light-selective transmissive zone can be located near the lens center and designed to reduce the transmission of any wave-length of visible light specifically light in the blue light region having wavelength between approximately 400? to 550?. In one embodiment he IOLs are made from acrylates and the light absorbing compound is a yellow dye.

Abstract: An intraocular lens for insertion into a capsular bag in order to focus incoming light toward a retina and process for manufacturing thereof along with concomitant reduced glare and improved vision provides for a center lens portion of a lens for focusing incoming light toward the retina and the surrounding lens portion for mounting the lens within the capsular bag. A surface roughness disposed on the surrounding lens portion is provided for reducing the glare due to non-focused light directed toward the retina from the intraocular lens with the roughness having a roughness level of between about Ra 45 and about Ra 350.

Abstract: An article for use in an OCT method, the article comprising a solid substrate and nanoparticles dispersed in or on the substrate in at least one light transmissive portion of the article such that the nanoparticles result in an increased extinction of the light transmissive portion along a transmission direction of the light transmissive portion compared to the substrate being free of nanoparticles. The extinction of the light transmissive portion along the transmission direction is less than 6, wherein the extinction is defined as a negative decadic logarithm of a ratio of an intensity of light which is transmitted through the light transmissive portion to an intensity of light which is incident on the light transmissive portion, wherein the light is in at least one of a visible and a near infrared wavelength range.

Abstract: Exemplary embodiments provide a coated intraocular lens that has a lens body with a first refractive index and an anti-reflective coating. The coating covers at least a portion of the lens body and has a second index of refraction that is less than the first index of refraction of the lens body. The anti-reflective coating reduces the intensity of reflections produced from off axis light incident on the lens body by at least a factor of 2.5 times and enhancing light transmission.

Abstract: A thin intraocular lens for inhibiting posterior capsular opacification (PCO) includes an optic having an anterior concave region, a posterior concave region, a sharp edge which extends posteriorly and between the posterior concave region and at least a portion of an outer-most peripheral edge surface.

Abstract: An intraocular implant including a plurality of mirrors, including mirrors having optical power, being operative, when the implant is implanted, for receiving light from a scene and focusing the light onto a retina, the mirrors containing bio-incompatible materials and at least one hermetically sealed enclosure, enclosing the plurality of mirrors, and being operative, when the implant is implanted, to seal the bio-incompatible materials from the interior of the eye, without interfering with the passage of light therethrough from the scene to the plurality of mirrors and from the plurality of mirrors to the retina.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: An intraocular lens for insertion into a capsular bag in order to focus incoming light toward a retina and process for manufacturing thereof along with concomitant reduced glare and improved vision provides for a center lens portion of a lens for focusing incoming light toward the retina and the surrounding lens portion for mounting the lens within the capsular bag. A surface roughness disposed on the surrounding lens portion is provided for reducing the glare due to non-focused light directed toward the retina from the intraocular lens with the roughness having a roughness level of between about Ra 45 and about Ra 350.

Abstract: An intraocular lens for inhibiting posterior capsular opacification, or secondary cataract, includes an optic having a periphery provided with at least two sharp edges which lie radially spaced from each other with respect to the optical axis of the lens optic.

Abstract: Opthalmic devices, particularity intraocular lenses (IOL), with improved contrast sensitivity and methods of making same. In one aspect, blue light blocking chromophores (BLBC) are diffused into, e.g. an IOL lens body to create a BLBC gradient in the lens. Orange dyes are preferred BLBCs.

Abstract: An intraocular implant including a plurality of mirrors, including mirrors having optical power, being operative, when the implant is implanted, for receiving light from a scene and focusing the light onto a retina, the mirrors containing bio-incompatible materials and at least one hermetically sealed enclosure, enclosing the plurality of mirrors, and being operative, when the implant is implanted, to seal the bio-incompatible materials from the interior of the eye, without interfering with the passage of light therethrough from the scene to the plurality of mirrors and from the plurality of mirrors to the retina.

Abstract: An intraocular lens for insertion into a capsular bag in order to focus incoming light toward a retina and process for manufacturing thereof along with concomitant reduced glare and improved vision provides for a center lens portion of a lens for focusing incoming light toward the retina and the surrounding lens portion for mounting the lens within the capsular bag. A surface roughness disposed on the surrounding lens portion is provided for reducing the glare due to non-focused light directed toward the retina from the intraocular lens with the roughness having a roughness level of between about Ra 45 and about Ra 350.

Abstract: A lens containing a chromophore distributed in or on the lens such that the lens functions as a virtual pupil in adjusting to light. The lens can be intraocular or extraocular.

Abstract: Intraocular lenses comprised of an acrylic-silicone hybrid polymer are disclosed. The intraocular lenses described herein are suitable for insertion through incisions of 2 mm or less.

Abstract: An intraocular implant, including an implant body adapted to have mounting haptics attached thereto, the implant body including a generally cylindrical portion and at least one sealing element mounted onto an end of the generally cylindrical portion, the intraocular implant also including at least one lens mounted within the implant body and an anti-glare coating layer covering at least part of an outer area of the generally cylindrical portion, and being operative to prevent glare caused by light rays passing through the implant body from obstructing a user's vision.

Abstract: An intraocular lens to be fixed in an eyeball has an optical pupil to provide a pinhole effect at the front center of the lens. The optical pupil is constituted by a limitative pattern that is partly formed in the front peripheral center of the lens to limit part of an optical path.

Abstract: A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.

Abstract: A thin intraocular lens for inhibiting posterior capsular opacification (PCO) includes an optic having a sharp edge which extends posteriorly and between a posterior concave region and an outer-most peripheral edge surface that extends parallel to the optical axis.

Abstract: A multi-element IOL, comprising an anterior lens element comprising a light-adjustable material responsive to light of a first wavelength, and a posterior lens element comprising a light blocker capable of blocking light of the first wavelength, and a method of inserting the multi-element IOL.

Abstract: The present invention describes a multi-focal intraocular lens for the human eye. The intraocular lens of the present invention provides improved vision quality over a range of object distances without producing glare or halos. It also provides non-symmetric, or nearly symmetric, optical zones about the lens optical axis.

Abstract: Exemplary embodiments provide a coated intraocular lens that has a lens body with a first refractive index and an anti-reflective coating. The coating covers at least a portion of the lens body and has a second index of refraction that is less than the first index of refraction of the lens body. The anti-reflective coating reduces the intensity of reflections produced from off axis light incident on the lens body by at least a factor of 2.5 times and enhancing light transmission.

Abstract: An intraocular lens for insertion into a capsular bag in order to focus incoming light toward a retina and process for manufacturing thereof along with concomitant reduced glare and improved vision provides for a center lens portion of a lens for focusing incoming light toward the retina and the surrounding lens portion for mounting the lens within the capsular bag. A surface roughness disposed on the surrounding lens portion is provided for reducing the glare due to non-focused light directed toward the retina from the intraocular lens with the roughness having a roughness level of between about Ra 45 and about Ra 350.

Abstract: A method is disclosed to place supplemental IOLs in the anterior chamber, posterior chamber or both, in combination with the eye's natural lens or a separate, implanted artificial lens.

Abstract: Methods and devices for inhibiting the dark shadow effect, known as dysphotopsia, perceived by some subjects having implanted intraocular lenses (IOLs) are presented. In one aspect, an IOL can include an optic and one or more fixation members for facilitating placement of the IOL. The fixation member can be adapted to position the optic sufficiently close to the iris to inhibit dysphotopsia. As some examples, a fixation member can position an optic to within some distance of the tip of the iris, or the fixation member can be adapted to contact a portion of an eye posterior to an optic's posterior surface; or the fixation member can have an end that is posterior to a posterior surface of the optic. Various techniques for achieving these improvements among others are discussed, both in terms of the structures of improved IOLs, and methods for alleviating dysphotopsia.

Abstract: In one aspect, an intraocular lens (IOL) is discloses that includes an optic having a central portion and a peripheral extension that partially surrounds the central portion. Once implanted in a patient's eye, the IOL's optic forms an image of a field of view with the peripheral extension inhibiting dysphotopsia. While in some embodiments, the peripheral extension provides focusing of light incident thereon, in other embodiments, it can include at least one textured surface for scattering the light or at least one opaque surface for preventing the light from reaching the retina. In other embodiments, the peripheral extension can include one or more translucent surface(s) for diffusing the light passing therethrough to inhibit dysphotopsia.

Abstract: Asymmetric intraocular lenses (IOLs) are disclosed in which the centration of the optic and the pupil can be adjusted in order to reduce dsyphotopsia and/or the perception of dark shadows. For example, IOLs with uneven haptics are disclosed such that the center of the optic (i.e., the optical axis) is offset from a centerline of the overall device.

Abstract: Devices and methods utilizing novel intraocular lens (IOL) designs are discussed herein. One aspect relates to IOLs having an optic with non-uniform light transmissivity. For example, the optic of the IOL can include a central region having a reduced light transmissivity relative to another portion of the optic. In addition, or alternatively, the optic can have a peripheral region having reduced light transmissivity. Such IOLs can potentially be utilized to alter the light distribution impinging on a subject's retina, which can be tailored to specific lighting situations such as bright and dim light conditions. Such IOLs can also, or alternatively, be used to help alleviate the perception of dark shadows known as negative dysphotopsia. Other aspects and features of IOLs, and methods, are also discussed.

Abstract: A method and apparatus for increasing the depth of focus of the human eye is comprised of a lens body, an optic in the lens body configured to produce light interference, and a pinhole-like optical aperture substantially in the center of the optic. The optic may be configured to produce light scattering or composed of a light reflective material. Alternatively, the optic may increase the depth of focus via a combination of light interference, light scattering, light reflection and/or light absorption. The optic may also be configured as a series of concentric circles, a weave, a pattern of particles, or a pattern of curvatures. One method involves screening a patient for an ophthalmic lens using a pinhole screening device in the lens to increase the patient's depth of focus. Another method comprises surgically implanting a mask in the patient's eye to increase the depth of focus.

Abstract: A method and apparatus for increasing the depth of focus of the human eye is comprised of a lens body, an optic in the lens body configured to produce light interference, and a pinhole-like optical aperture substantially in the center of the optic. The optic may be configured to produce light scattering or composed of a light reflective material. Alternatively, the optic may increase the depth of focus via a combination of light interference, light scattering, light reflection and/or light absorption. The optic may also be configured as a series of concentric circles, a weave, a pattern of particles, or a pattern of curvatures. One method involves screening a patient for an ophthalmic lens using a pinhole screening device in the lens to increase the patient's depth of focus. Another method comprises surgically implanting a mask in the patient's eye to increase the depth of focus.

Abstract: An ophthalmic lens, comprising an optic including at least one photochromic region having a first chromaticity and a second region of lesser photochromaticity.

Abstract: An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens and includes a plurality of periodically-spaced protrusions, each protrusion having a smooth distal face and a sharp corner edge configured to engage a wall of the capsular bag and/or at least one cell disposed along the wall.

Abstract: An intraocular lens for providing vision to a subject contains an optic, a support structure coupled to the optic. The intraocular lens also includes a textured surface and/or subsurface layer. The optic is disposed about an optical axis and comprises an anterior surface and an opposing posterior surface, the surfaces being configured to focus light when implanted within an eye having a capsular bag. The textured surface is disposed over a surface portion of the intraocular lens and includes a plurality of periodically-spaced protrusions, each protrusion having a smooth distal face and a sharp corner edge configured to engage a wall of the capsular bag and/or at least one cell disposed along the wall.

Abstract: An intraocular lens implantable in an eye includes an optic for placement in the capsular bag of the eye and for directing light toward the retina of the eye. The optic has a central optical axis, an anterior face, an opposing posterior face and a peripheral edge between the faces. The peripheral edge has one or more curved or angled surfaces that reduce glare within the IOL. For instance, a rounded transition surface on the anterior side of the peripheral edge diffuses the intensity of reflected light, or a particular arrangement of straight edge surfaces refracts the light so as not to reflect, or does not reflect at all. The intersection of the peripheral edge and at least one of the anterior face and the posterior face, preferably both of such faces, forms a peripheral corner located at a discontinuity between the peripheral edge and the intersecting face or faces.

Abstract: An ocular lens treated so that at least a portion of the lens perimeter diminishes peripheral light focus on the interior of the eye in use, so as to ameliorate phobic eye disturbances. The lens perimeter of intraocular lenses, artificial corneas and contact lenses are treated to diminish peripheral light focus.

Abstract: A narrow profile, glare reducing, posterior chamber intraocular lens comprises an optic having an anterior surface and a posterior surface and an optical axis. The posterior surface is formed having two adjacent peri-axial, stepped imaging zones, the two imaging zones having the substantially the same optical power. A transition zone between the two imaging zones preferably has a surface of continuous curvature shaped to reduce direct glare from light incident on the transition zone in an individual's eye in which the intraocular lens is implanted by internal reflection of direct light incident on the transition zone. Attachment members joined to the optic position the intraocular lens in an eye with the optical axis of the optic generally aligned with the optical axis of the eye. In variations, the transition zones are formed at the optic edge to minimize direct and indirect in the eye of an individual wearing the intraocular lens.

Abstract: The present invention relates to an intraocular correction lens for implantation in the posterior chamber of the eye between the iris and the intact natural lens. The lens has a concave posterior surface which is part of a non-spherical surface that is rotation symmetric around the optical axis of said optical part, wherein the intersection between said non-spherical surface and any plane containing the optical axis of the lens represents a flawless curve free from discontinuities and points of inflection. The invention also relates to methods of selecting correction lenses based on estimations of the individual eye in need of vision correction and thereby arriving with a correction lens with a high safety for wearer with respect to surrounding eye tissues.