Abstract: An intraocular lens has a polymeric optic defined by a harder posterior layer and a softer anterior layer. Haptics having a fulcrum attached to the posterior layer and a resistance arm attached to the anterior layer are provided. A bias is provided to the haptic to rotate the haptics about the fulcrum and cause the resistance arm to deform the softer anterior layer about the harder posterior layer to increase the optical power of the lens. As the haptic rotates, it axially displaces the optic anteriorly to additionally increase the optical power. The optical power is adjustable in response to stresses induced by the eye. The haptics are subject to a pre-bias that urges the haptics to rotate or bend about the fulcrum. Temporary restraints are provided to the haptics to retain a stressed shape of the lens against the bias during a post-implantation healing period.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: The present invention is directed to an intraocular lens, an intraocular lens system and a method of producing and/or implanting the lens or system in an eye wherein at least one intraocular lens includes a coating that aids in resisting interlenticular opacification (ILO). The material of the coating is preferably hydrophilic or super-hydrophobic.

Abstract: The various embodiments of the present invention provide a multi-optics intraocular lens (IOL) scaffold assembly for incorporation into a capsular bag of an eye of a subject, provided with a ring platform and a protective umbrella. Several anterior and posterior ribs are hinged to the ring platform to support a posterior lens and an anterior lens. The dynamic spring elastic junctions are provided between the anterior and posterior ribs. The pendulum IOL assembly of the multi-optics intraocular lens (IOL) scaffold assembly enables a near vision of the objects using an optical system designed for a distance focusing in normal gaze. The pendulum IOL assembly has a posterior lens fixed to an equatorial ring platform and a secondary hanging lens provided with a weight at the lower end to act like a pendulum which swings with the posture of the eye.

Abstract: An accommodative intraocular lens (IOL) system is disclosed for insertion into an eye to provide accommodative vision, the system including a first lens having an first optic, a second lens having a second optic, a transparent, low refractive index medium disposed between the first and second optics; and at least one haptic connected to the first and second lenses and configured to facilitate movement of one lens relative to the other lens, such that when the lens system is positioned in an eye, ciliary muscle movements can alter the distance between the first and second lenses and vary the overall lens power of the system.

Abstract: Intraocular lenses for providing accommodation include an anterior optic, a posterior optic, and a lens structure. In one such lens, the lens structure comprises an anterior element coupled to the anterior optic and a posterior element coupled to the posterior optic. The anterior and posterior elements are coupled to one another at a peripheral region of the intraocular lens. The intraocular lens may also includes a projection extending anteriorly from the posterior element that limits posterior motion of the anterior optic so as to maintain a minimum separation between anterior optic and an anterior surface of the posterior optic.

Abstract: In one aspect, the present invention provides a two-element ophthalmic lens in which a lateral shift of the elements relative to one another can cause a variation not only in a spherical power provided by the lens but also in spherical aberration exhibited by that lens. In some implementations, the thickness profiles of the two elements are designed such that the variation in spherical aberration is positively correlated with that of the spherical power of the lens.

Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

Abstract: A novel lens for variable focus has two optical elements which simultaneously move in a lateral and an axial direction. The lens also includes variable corrective optics to correct for undesired variable optical aberrations. The lens can be used as an accommodating lens for implantation in the capsular bag. The lens can be driven by either the surfaces of the capsular bag as well as the rim of the capsular bag.

Abstract: An adjustable multifocal intraocular lens system for an individual's eye, includes a base multifocal intraocular lens having an optic with an optical axis, a peripheral edge, a multifocal optical power anterior surface and a posterior surface along with an attachment for maintaining the base multifocal lens in the individual's eye with the optical axis centered along an eye optical axis. An enhanced multifocal intraocular lens is provided with an optic with a peripheral edge, an anterior surface and a reverse multifocal optical power posterior surface, and a coupling enables assembly of the base lens and enhance lens with the enhance lens posterior surface overlaying the base lens anterior surface in order that the enhance intraocular lens reverse multifocal surface adjust multifocal powers of the base IOL by substantially masking near power of the base multifocal intraocular lens.

Abstract: Unitary accommodating intraocular lenses (AIOLs) including a haptics system for self-anchoring in a human eye's ciliary sulcus and a resiliently elastically compressible shape memory optical element having a continuously variable Diopter strength between a first Diopter strength in a non-compressed state and a second Diopter strength different than its first Diopter strength in a compressed state. The unitary AIOLS include an optical element with an exposed trailing surface and are intended to be used with a discrete base member for applying an axial compression force against the exposed trailing surface from a posterior direction. Some unitary AIOLs are intended to be used with either a purpose designed base member or a previously implanted standard in-the-bag IOL. Other unitary AIOLs are intended to be solely used with a purpose designed base member.

Abstract: The invention relates to an accommodative lens implant controlled by the ciliary muscle, consisting of at least one or more lenses made of preferably biocompatible material and disposed on a common optical axis, the at least one lens being a component of a flexible, closed implant body that is transparent in the region of the actual lens, is engaged at its outer periphery with the ciliary muscle, and has a main axis that coincides with the visual axis, and in addition at least part of the implant body with the lens or lenses comprises a fluid filling, such that the axial position of the lens or the lens system can be altered by activation of the ciliary muscle, the implant body being inserted in the sulcus of the posterior chamber of the eye or attached to the ciliary muscle.

Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.

Abstract: An intraocular device including a prism and shift amplifier is provided. Also provided is a system containing the intraocular device, and a method for improving vision of a person with central vision loss. The method involves implanting the intraocular device in the person so that the prism and shift amplifier cumulatively shift a retinal image away from the fovea of an eye to a functional retinal portion of the eye. Also provided is a method for correcting a binocular misalignment of a person using the intraocular device.

Abstract: A fluid lens assembly including a front rigid lens, a semi-flexible membrane that is adapted to be expanded from a minimum inflation level to a maximum inflation level, and a fluid layer therebetween. The front lens of the fluid lens assembly is configured to have a negative optical power. In an embodiment, the fluid lens assembly may be configured to have an overall negative optical power when the membrane is expanded to the maximum inflation level. In an embodiment, the fluid lens assembly can be configured to have an overall negative optical power when the membrane is expanded between the minimum inflation level and the maximum inflation level.

Abstract: The present invention discloses a multi-component intraocular lens implanted in an optical system of a human eye, including one or more foldable removable components, each component being foldable. One component acts as a base lens, including a flange with a slot. Another component acts is an optical assembly that may include a top lens joined to or integrated with a mid lens. The top lens, the mid lens or the optical assembly may include at least one projection that engages the slot of the base lens. The top and mid lenses are manufactured from a material having adhesive properties, wherein the top and mid lenses adhere to each other free of any material or substance being present therebetween.

Abstract: A multi-component intraocular lens implanted in an optical system of a human eye includes one or more removable components, each component being foldable. One component acts as a base lens, including a flange with an aperture. Another component acts as a mid lens, including a tab which engages the aperture. A third component acts as a top lens, which engages the mid lens. Because the lens components are foldable, they may be inserted into the eye using an incision smaller than the diameter of the unfolded lens. The removable components may be used to correct various medical conditions of the eye, as well as to improve and enhance vision, and for cosmetic purposes.

Abstract: An accommodating intraocular lens implantable in an eye. The lens comprises an anterior portion having an anterior biasing element and an anterior optic having refractive power. The lens further comprises a posterior portion having a posterior biasing element and a posterior optic having refractive power. The anterior optic and the posterior optic are relatively moveable in response to action of the ciliary muscle to change the separation between the optics and the refractive power of the lens. The lens has an aberration-inducing force characteristic of about 70 mg to about 115 mg to allow aberration-inducing relative movement of the optics when the lens is in the eye, thereby adding optical aberration to the lens which increases depth of focus of the lens. In one variation, the lens has an aberration-inducing force characteristic of 70 mg to 115 mg. Related methods are also disclosed.

Abstract: This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

Abstract: An Accommodating Intraocular Lens (AIOL) is disclosed herein, that is comprised of a flexible optic and a flexible haptic rim that conforms to the human eye capsule. The spherical or custom shape of the optic is engineered to be maintained during accommodation through the mechanical/optic design of the implant and the interaction between the implant and the naturally occurring position and actuating forces applied through ciliary muscle/zonules/and capsule as the brain senses the need to increase the diopter change or magnification when an object of fixation approaches the eye. The axial relocation or position of the AIOL may also be further adjusted anatomically to further improve the affect needed to achieve improved accommodation. Optionally, the accommodating intraocular lens is foldable or injectable for delivery of the lens into the eye.

Abstract: A two optic accommodative lens system wherein at least one of the optics is deformable. When compressed by the capsular bag, the two optics press against each other, deforming at least one of the optics. As a result, the interface where the two optics meet changes shape, thereby altering the refractive power of the lens system.

Abstract: The present invention is generally directed to accommodative intraocular lenses (IOLs) that exhibit a dynamic spherical aberration as a function of accommodative power. By way of example, in one aspect, the present invention provides an intraocular lens (IOL) having an anterior optical element, a posterior optical element, and a mechanism for coupling the anterior and posterior elements so as to allow axial movement of those elements relative to one another for providing accommodation when the lens is implanted in a patient's eye. Each of the anterior and the posterior elements includes at least one aspherical surface, where the asphericities of the surfaces are adapted to provide a combined spherical aberration that varies with accommodation.

Abstract: A lens system is provided. The lens system includes a lens adapted to be positioned along the main optical axis of the eye and a control unit. The control unit is operable with the lens to alter the focal length of the lens based at least partly upon a condition, such that the lens alters light rays and focuses the rays on the retina of the eye.

Abstract: An accommodating intraocular lens comprising an optic made from solid silicone and liquid silicone. The optic has a central anterior area or membrane that can vary in radius and thus charge power.

Abstract: Visual aids and associated methods for improving the eye sight of low vision patients are provided. Generally, the devices of the present disclosure address the needs of age-related macular degeneration (AMD) and other low vision patients by providing a magnified retinal image while keeping a large visual field of view. Further, the devices of the present disclosure allow direction of the magnified retinal image away from damaged portions of the retina and towards healthy, or at least healthier, portions of the retina. The devices of the present disclosure are also configured for implantation within the eye using minimally invasive surgical procedures. Methods of utilizing the devices of the present disclosure, including surgical procedures, are also provided.

Abstract: An intraocular telescopic lens assembly including a negative lens having a negative lens optical axis, a positive lens having a positive lens optical axis and a spacer disposed intermediate the negative lens and the positive lens, the spacer being operative to maintain mutual orientation of the negative lens and the positive lens such that the negative lens optical axis is coaxial with the positive lens optical axis.

Abstract: A multi-component intraocular lens implanted in an optical system of a human eye, includes one or more removable components. One component acts as a base lens and another component acts as the front lens. A front lens formed from two integral optical portions may be milled with tabs to establish an axial orientation of the front lens. The front lens may have a different diameter than the base lens. The base lens may have sharp or angled edges and the front lens may have rounded edges. Non-optical portions of the intraocular lens system may be manufactured from a material that is capable of releasing a pharmacological agent. A flange may be fused with the base lens to allow the front lens to engage with the base lens.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

Abstract: An accommodating intraocular artificial lens with variable optical power, comprising two optical elements which are adapted to mutually shift in a direction perpendicular to the optical axis wherein the optical elements have such a shape that the optical elements exhibit, in combination, different optical powers at different relative positions. Flanges are adapted to position the anterior section of the haptics in the sulcus of the eye or, alternatively, the ciliary body is enclosed by a combination of anterior and posterior flanges. Also disclosed are methods to provide for an accommodating intraocular lens which is adjustable post-implant to ensure emmetropia of the eye.

Abstract: A multi-component intraocular lens implanted in an optical system of a human eye, including one or more foldable removable components, each component being foldable. One component acts as a base lens, including a flange with a slot. Another component acts an optical assembly that may include a top lens joined to or integrated with a mid lens. The top lens, the mid lens or the optical assembly may include at least one projection that engages the slot of the base lens. A medical adhesive may be applied to an outer circumferential surface of the top lens to join the top lens to the mid lens or may be applied to a top surface of the top lens opposing a bottom surface of the mid lens.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.

Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.

Abstract: An open chamber, accommodative, intraocular lens system operable to be positioned within the interior of an evacuated capsular bag of a human eye. The present invention provides new haptic cross-sections, novel complex lens structures by introduction of the concept of a lens ledge, fixation of haptics to lenses at a lens ledge, structural solutions to provide customized fitted correction, and accordion structural solutions to ease the insertion of complex lenses into the capsular bag of the eye.

Abstract: A prosthesis is provided, which includes anterior and posterior lenses spaced from one another and aligned along an optical axis, and an optic body supporting the lenses in spaced relation to one another to establish a chamber between the lenses. Optically transmissive primary and secondary fluids are contained in the chamber. Orienting the optical axis in a horizontal orientation for far vision positions the optical axis through the primary fluid. Orienting the optical axis for near vision at a range of effective downward angles relative to the horizontal orientation positions the optical axis to extend through the primary fluid and the secondary fluid. The prosthesis may further include an internal plate between the lenses, which may be offset at an oblique angle relative to perpendicular to the optical axis. Related methods are also provided.

Abstract: A two-optic accommodative lens system is disclosed. Two coupled lenses are located within the capsular bag to extend depth of focus and/or restore accommodation following extraction of a natural lens. The first lens comprises a spring-like structure attaching an optic to a ring-like support structure. The optic can be a monofocal or multifocal optical element having a positive or negative power. The first lens further comprises features designed to couple the ring-like structure to a second lens. The first lens can be located anteriorly within the capsular bag. The second lens is located posteriorly to the first lens within the capsular bag and can have an opposite or supplementary power to that of the first lens. The second lens can also be a monofocal or multifocal lens and comprises a plurality of haptics which can be used to size the lens system over a range of capsular bag sizes. The second lens further comprises features for coupling the second lens to the ring-like structure of the first lens.

Abstract: An artificial vision system including a sealed capsule adapted for intraocular placement upstream of a retina, an electronic display located within the sealed capsule and focusing optics located within the sealed capsule and arranged for focusing an image on the electronic display onto the retina.

Abstract: An artificial vision system including a sealed capsule adapted for intraocular placement upstream of a retina, an electronic display located within the sealed capsule and focusing optics located within the sealed capsule and arranged for focusing an image on the electronic display onto the retina.

Abstract: Unitary accommodating intraocular lenses (AIOLs) including a haptics system for self-anchoring in a human eye's ciliary sulcus and a resiliently elastically compressible shape memory optical element having a continuously variable Diopter strength between a first Diopter strength in a non-compressed state and a second Diopter strength different than its first Diopter strength in a compressed state. The unitary AIOLS include an optical element with an exposed trailing surface and are intended to be used with a discrete base member for applying an axial compression force against the exposed trailing surface from a posterior direction. Some unitary AIOLs are intended to be used with either a purpose designed base member or a previously implanted standard in-the-bag IOL. Other unitary AIOLs are intended to be solely used with a purpose designed base member.

Abstract: Intraocular lenses for providing accommodation include an anterior optic, a posterior optic, and a lens structure. In one such lens, the lens structure comprises an anterior element coupled to the anterior optic and a posterior element coupled to the posterior optic. The anterior and posterior elements are coupled to one another at a peripheral region of the intraocular lens. The intraocular lens may also includes a projection extending anteriorly from the posterior element that limits posterior motion of the anterior optic so as to maintain a minimum separation between anterior optic and an anterior surface of the posterior optic.

Abstract: An open chamber, accommodative, intraocular lens system operable to be positioned within the interior of an evacuated capsular bag of a human eye. The present invention provides new haptic cross-sections, novel complex lens structures by introduction of the concept of a lens ledge, fixation of haptics to lenses at a lens ledge, structural solutions to provide customized fitted correction, and accordion structural solutions to ease the insertion of complex lenses into the capsular bag of the eye.

Abstract: In one aspect, the present invention provides an intraocular lens (IOL), which comprises at least two optics disposed in tandem along an optical axis, and an accommodative mechanism that is coupled to at least one of the optics and is adapted to adjust a combined optical power of the optics in response to natural accommodative forces of an eye in which the optics are implanted so as to provide accommodation. At least one of the optics has a surface characterized by a first refractive region, a second refractive region and transition region therebetween, where an optical phase shift of incident light having a design wavelength (e.g., 550 nm) across the transition region corresponds to a non-integer fraction of that wavelength.

Abstract: The present invention discloses a multi-component intraocular lens implanted in an optical system of a human eye, including one or more foldable removable components, each component being foldable. One component acts as a base lens, including a flange with a slot. Another component acts is an optical assembly that may include a top lens joined to or integrated with a mid lens. The top lens, the mid lens or the optical assembly may include at least one projection that engages the slot of the base lens. The top and mid lenses are manufactured from a material having adhesive properties, wherein the top and mid lenses adhere to each other free of any material or substance being present therebetween.

Abstract: An in-phase intracorneal lens system that prevents substantial movement between connected lenses to provide high resolution of the eye. A first lens is adapted to be positioned on a surface of a cornea. A second lens has a substantially ring-shaped configuration and is substantially concentric with the first lens. At least one first bridge member extends from the first lens to the second lens to couple the first lens to the second lens to prevent substantial movement between the first and second lenses.

Abstract: An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.

Abstract: A multi-component accommodating intraocular lens (A-IOL) for implantation in a capsular bag of an eye having an optical axis, includes an anterior optical element and a posterior component that are connected by at least one compressible haptic. The compressible haptic, by definition, has a deformation feature that is resiliently deformable. The deformation feature allows the nominal overall diameter of the A-IOL to dynamically vary over a selected range in response to a capsular bag dimension that is different than that of an average population value, or in response to a change in the size and/or shape of the capsular bag due to post-operative capsular bag shrinkage, without substantially changing the separation distance between the anterior and posterior components of the A-IOL absent an intended accommodating force. Methods are also disclosed.

Abstract: Disclosed are accommodating intraocular lenses for implantation in an eye having an optical axis. In certain embodiments, an intraocular lens includes an anterior optic, a posterior optic, and a support structure configured to move the optics relative to each other along an optical axis between an accommodated state and an unaccommodated state. In certain embodiments, at least a portion of the support structure can be modified in situ to alter reaction forces between the support structure and at least one structure of the eye. In certain embodiments, a refractive property of one of the anterior or posterior optics can be modified in situ while leaving the refractive properties of the remaining one of the anterior or posterior optics substantially unaffected. Additional embodiments and methods are also disclosed.

Abstract: A method for prevention of migration of epithelial cells in a capsular bag of an eye of a mammal is provided. The method comprises removing the natural lens of the eye from the capsular bag; introducing an object with at least one sharp edge into the capsular bag, in such a way that said sharp edge contacts the inside of the capsular bag to form a barrier preventing migration of epithelial cells across said barrier; and injecting a lens-forming composition into the capsular bag.