Abstract: Disclosed are toric accommodating intraocular lenses. In one embodiment, a toric accommodating intraocular lens comprises an anterior element and a posterior element. The anterior element can comprise an anterior optical surface. The posterior element can comprise a posterior optical surface. A fluid-filled optic fluid chamber can be defined in between the anterior element and the posterior element. The toric accommodating intraocular lens can be configured to correct for corneal astigmatism, spherical aberration, or a combination thereof.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a mask adapted to increase depth of focus. The method of manufacturing the implant can include positioning the mask with an aperture on a protruding pin of a positioning mold portion. The protruding pin can be configured to center the mask in the intraocular lens.

Abstract: An improved self-centering phakic refractive lens is disclosed. The lens floats freely in the posterior chamber of the eye and corrects vision of the patient but also prevents buildup of intraocular pressure, cataract induction and iris pigment dispersion. The lens comprises an optical body, haptic members which extend outward from the optical body, and a small hole in the approximate center of the optical body for the purpose of allowing aqueous humor to flow through that hole. The lens is designed such that its posterior surface conforms to the shape of the anterior surface of the patient's natural crystalline lens.

Abstract: A method of performing laser surgery in a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form an enclosed treatment pattern that is configured to form an enclosed capsulorhexis incision that includes a registration feature, and delivering the enclosed treatment pattern to target tissue in the patient's eye to form in an anterior lens capsule of the patient's eye the enclosed capsulorhexis incision that includes the registration feature. The registration feature is configured so that an edge of the target tissue formed by the enclosed capsulorhexis incision mates with an intraocular lens registration feature on an intraocular lens so as to rotationally register the intraocular lens relative to the registration feature.

Abstract: A prosthetic capsular device configured to be inserted in an eye includes a housing structure and a ring structure. The housing structure includes a first side, a second side opposite the first side, a third side, a fourth side opposite the third side, a posterior side including a refractive surface, an anterior side opposite the posterior side, and a longitudinal axis. The first side, the second side, the third side, the fourth side, the posterior side, and the anterior side at least partially define a cavity configured to contain an intraocular device (e.g., an IOL). The anterior side includes an opening. The ring structure includes a ring structure portion extending radially outward from proximate one of an end of the first side and an end of the second side.

Abstract: A haptic is provided for use in an accommodating intraocular lens. The haptic has multiple filaments, each connected to the edge of the optic at one end. Each filament has a shape that conforms to an equatorial region of the capsular bag. The haptic couples the forces exerted by the capsular bag of the eye during accommodation radially to the edge of the optic, produce a diametric expansion or compression of the optic. This diametric motion distorts the optic, producing a change in any or all of the anterior radius, the posterior radius, and the thickness. These changes affect the power of the lens and/or location of the image. The haptic may optionally have a thin membrane joining the filaments at the optic end, and may optionally have a connecting ring that joins the filaments at the end opposite that of the optic.

Abstract: An intraocular lens is disclosed with an optic that changes shape in response to forces exerted by the zonules of the eye. A haptic with an inner and outer ring couples the optic to the capsular bag of the eye. The haptic stresses the optic when the intraocular lens is in a natural state such that the internal stress is present throughout the accommodation range in order to prevent ripples and/or waves in the optic.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.

Abstract: An accommodating intraocular lens for providing a range of accommodative vision contains an optic and a haptic. The haptic includes a plurality of arms coupled to a compressible inner structure. The compressible inner structure of the haptic is configured to exert a compressive force on the optic in response to an ocular force to provide accommodation. The compressible inner structure can include a plurality of arcuate segments that join to form a ring in the fully compressed state or a sinusoidal ring having a varying radial dimension.

Abstract: An accommodating intraocular lens (AIOL) comprising an optic, and at least one haptic plate coupled to the optic by at least one connector, the connector being less rigid than the haptic plate, the at least one haptic plate surrounding the optic, and the optic and haptic plate having a combined surface area between 70 mm2 and 100 mm2. The at least one haptic plate may form a continuous 360-degree boundary around the optic. The at least one haptic plate has a width in a radial dimension of 1.0-3.5 mm across its entire angular extent.

Abstract: The present invention relates to a prosthetic capsular bag and method for inserting the same. The prosthetic capsular bag helps to maintain the volume of the natural capsular bag, thereby stabilizing the effective lens position of an IOL so that refractive outcomes may be improved with cataract surgery. The prosthetic capsular bag further provides an integrated refractive surface, providing a means for experimentally determining an effective lens position prior to inserting an IOL.

Abstract: A two-optic accommodative lens system is disclosed. Two coupled lenses are located within the capsular bag to extend depth of focus and/or restore accommodation following extraction of a natural lens. The first lens comprises a spring-like structure attaching an optic to a ring-like support structure. The optic can be a monofocal or multifocal optical element having a positive or negative power. The first lens further comprises features designed to couple the ring-like structure to a second lens. The first lens can be located anteriorly within the capsular bag. The second lens is located posteriorly to the first lens within the capsular bag and can have an opposite or supplementary power to that of the first lens. The second lens can also be a monofocal or multifocal lens and comprises a plurality of haptics which can be used to size the lens system over a range of capsular bag sizes. The second lens further comprises features for coupling the second lens to the ring-like structure of the first lens.

Abstract: An accommodative intraocular lens having a soft deformable resilient inner lens portion or core with an exposed anterior inner optic surface and exposed posterior optic surface, the surfaces responsively becoming simultaneously optically steeper and moving axially away from each other. The exposed anterior and posterior surfaces of the inner lens portions may be spherically shaped or aspherically shaped and the shape of the outer lens portion may be spherically or aspherically shaped.

Abstract: Disclosed is an intraocular lens supporter having a control ability. One embodiment of the present invention provides an intraocular lens supporter that is inserted into a capsular sac, including a first face coming in contact with an inner surface of the capsular sac in at least one point as a structural body that is extended along an equatorial region of the capsular sac; and a second face arranged opposite to the first face, wherein, in a section where the structural body is cut along a virtual plane in a visual axis direction (Y direction) of an eye lens, the first face is provided at a length as much as ¾ to 3 times of a length (d5, d10) of a region where an zonule of Zinn is coupled to an outer surface of the capsular sac.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: An intraocular lens for providing accommodative vision includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises a central zone and an annular zone surrounding the central zone. The optic may also comprise additional annular zones. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power. The central zone and the annular zone have different optical powers when the adjustable intraocular lens is in the accommodative configuration and/or when the adjustable intraocular lens is in the disaccommodative configuration.

Abstract: An accommodating intraocular lens (IOL) comprises an anterior lens, a posterior surface and an articulating member joining the anterior lens and the posterior surface to define an enclosed cavity. The articulating member comprises anterior and posterior arms coupling the anterior lens and the posterior surface, respectively. The articulating member further comprising a peripheral portion. A posterior flex region is disposed about the posterior arm and at a distance from the peripheral portion. The posterior flex region permits the flexible posterior surface to articulate relative to the posterior arm, to decrease the radius of curvature of the posterior surface as the peripheral portions on opposing sides of the IOC move toward one another in a first state and to increase the radius of curvature of the posterior surface as the peripheral portions on opposite sides of the IOC move away from one another in a second state.

Abstract: An IOL having an optic and a peripheral stabilizing ring. The optic and the ring are connected by a flexible bridge. An area on the ring coinciding with a feature on the optic helps to locate the optic within the ring in an unstressed state until the capsular bag collapses and locks the optic into place.

Abstract: An exchangeable intraocular lens device having a flexible, high-memory expansile lens fixation platform adapted to receive the haptics of an intraocular lens, and their method of use, are provided. The device is specifically designed to expand completely into the equatorial fornix of the capsular bag and become permanently implanted therein. The design of the present invention addresses the desire of patients to exchange their existing intraocular lens to meet their changing visual needs or to take advantage of improved lens technology, without incurring the significant risks typically associated with exchange of current intraocular lens technology. The exchangeable intraocular lens device provides accurate centration, positioning, and stability of the intraocular lens in the capsular bag. The exchangeable intraocular lens device reduces lens epithelial cell migration and resultant posterior capsule opacification.

Abstract: An intraocular lens implant includes a lens having an anterior portion, a posterior portion, and a circumferential edge located therebetween. An annular notch is formed in the anterior portion and oriented in an anteriorly-directed orientation.

Abstract: An accommodating artificial ocular lens (AAOL) device including a lens optic portion connected to a pleated lens haptic portion to provide accommodation of vision of the eye.

Abstract: Disclosed is an intraocular lens assembly provided inside a capsular sac. The intraocular lens assembly according to one embodiment of the present invention includes an intraocular lens and an intraocular lens supporter, and therefore the intraocular lens assembly may be useful to transfer a force to the intraocular lens, inserted inwardly into the capsular sac, to allow the intraocular lens to move like a natural eye lens, the force being generated from the ciliaris muscle and transferred through the zonule of Zinn and the capsular sac.

Abstract: Disclosed is an intraocular lens that is inserted inwardly into a capsular sac. One embodiment of the present invention provides an intraocular lens inserted inwardly into a capsular sac including an optic portion including a first optic body whose central region has a smaller thickness than a circumference of the central region and a second optic body coupled to the first optic body and whose central region has the same or higher thickness as/than the first optic body; and a haptic portion including a connection bar coupled to the optic portion and first support bar coupled to a circumference of the connection bar to be in contact with an inner surface of the capsular sac.

Abstract: A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.

Abstract: A device includes a plurality of ringlets connected together to form a ring having a longitudinal axis. Each ringlet includes a first element and a second element. The first and second elements each extend from a first end through a central portion to a second end. The first and second ends are disposed at radially outer positions with respect to the ring than the central portion. The central portion is longitudinally displaced from the first and second ends. The first and second elements are separated and spaced apart from each other at the central portions thereof and are joined together at the first ends thereof and the second ends thereof. The ringlets are connected together such that the first ends of the elements of one ringlet are connected to the second ends of the elements of an adjacent ringlet.

Abstract: The invention provides for an inflatable intra ocular lens/lens retainer or a system of inflatable intra ocular lens/lens retainers, which are fitted into an aphakic eye, to substantially occupy the space previously held by the crystalline lens to retain and secure the position of delicate intra ocular structures of the eye. The inflatable lens/lens retainer may also be used suspend optical interfaces along the visual axis of the eye. The inflatable intra ocular lens/lens retainer may be pressed against residual elements of the lens capsule to re-establish accommodation. In the absence of a lens capsule, the inflatable intra ocular lens/lens retainer may be compressed directly by the ciliary muscle to alter the refractive state of the eye.

Abstract: An implantable, compressible, accommodating intra-ocular lens (IOL) coupled to at least one sensor which detects a signal created by the ciliary muscle. A ciliary sulcus ring can house the at least one sensor, and the sensor can include miniaturized electrodes (ciliary muscle probes) for implanting into the ciliary muscle of the subject. A potentiometer/microcomputer can modulate the ciliary muscle signal detected by the sensor(s) into an electrical signal, and a transmitter sends this electrical signal to a micromotor, which causes compression of the IOL via an annular support ring system, causing a change in the IOL shape. The IOL can be part of an IOL complex including a compressible, accommodating IOL, an external lens membrane, and an annular support ring system. The annular support ring system provides a foundation for the micromotor to compress the IOL.

Abstract: Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: A flexible intraocular implant for placing in a capsular bag, the implant comprising an optical portion of substantially circular shape that presents an optical axis, and a haptic portion connected to the periphery of the optical portion, said haptic portion comprising: a contact portion constituted by n (n?2) contact elements in the form of circular arcs all having the same radius of curvature and each having an outer edge that is in contact with the equatorial zone of the capsular bag, and n connection elements, each connection element being connected via respective ends to two consecutive contact elements, presenting a deformable curved shape, and presenting stiffness that is much less than that of the contact elements; and n deformable connection arms each connected to the periphery of the optical portion and to a contact element.

Abstract: Fluid-driven accommodating intraocular lenses comprising deformable optic portions.

Abstract: An accommodating artificial ocular lens (AAOL) device including a moving lens optic portion connected to a lens plate haptic portion. Preferably, the lens optic portion is connected to the lens plate haptic portion by a pair of flexible or resilient transverse oriented lens arm portions to provide or allow for movement of the lens optic portion.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and hinged portions longitudinally connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: An injectable intraocular implant including an optics portion and a resilient, flexible haptics portion mounted coaxially with the optics portion and a method for inserting the implant into the eye.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and a weakened portion connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: A multi-component intraocular lens implanted in an optical system of a human eye includes one or more removable components, each component being foldable. One component acts as a base lens, including a flange with an aperture. Another component acts as a mid lens, including a tab which engages the aperture. A third component acts as a top lens, which engages the mid lens. Because the lens components are foldable, they may be inserted into the eye using an incision smaller than the diameter of the unfolded lens. The removable components may be used to correct various medical conditions of the eye, as well as to improve and enhance vision, and for cosmetic purposes.

Abstract: An intraocular lens for providing accommodative visions to a subject includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises an optical axis, a central zone disposed about the optical axis, and an annular zone surrounding the central zone. The optic may also comprise additional annular zones disposed about the central zone and the first annular zone. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power, preferably at least about 2 Diopters greater than the base optical power. In some embodiments, the add optical power is at least 3 Diopters, or even 4 Diopters, greater than the base optical power.

Abstract: A device includes a plurality of ringlets connected together to form a ring having a longitudinal axis. Each ringlet includes a first element and a second element. The first and second elements each extend from a first end through a central portion to a second end. The first and second ends are disposed at radially outer positions with respect to the ring than the central portion. The central portion is longitudinally displaced from the first and second ends. The first and second elements are separated and spaced apart from each other at the central portions thereof and are joined together at the first ends thereof and the second ends thereof. The ringlets are connected together such that the first ends of the elements of one ringlet are connected to the second ends of the elements of an adjacent ringlet.

Abstract: An intraocular lens is disclosed, with an adjustable optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The haptic may include a cap on the anterior and/or posterior surfaces of the lens. The lens may include a force transfer member, such as a hinge, that couples forces from the haptic to the cap, so that a radial force on the haptic changes the curvature of the cap. The haptic and optic may be refractive index-matched. The cap may be made of the haptic material, which is stiffer than the optic material, and can influence the deformation of the lens during accommodation. A cap on the anterior surface may produce an axial movement of the lens in an anterior direction during accommodation. The cap may also protect the surfaces of the optic during handling and installation.

Abstract: An Accommodating Intraocular Lens (AIOL) is disclosed herein, that is comprised of a flexible optic and a flexible haptic rim that conforms to the human eye capsule. The spherical or custom shape of the optic is engineered to be maintained during accommodation through the mechanical/optic design of the implant and the interaction between the implant and the naturally occurring position and actuating forces applied through ciliary muscle/zonules/and capsule as the brain senses the need to increase the diopter change or magnification when an object of fixation approaches the eye. The axial relocation or position of the AIOL may also be further adjusted anatomically to further improve the affect needed to achieve improved accommodation. Optionally, the accommodating intraocular lens is foldable or injectable for delivery of the lens into the eye.

Abstract: A two optic accommodative lens system wherein at least one of the optics is deformable. When compressed by the capsular bag, the two optics press against each other, deforming at least one of the optics. As a result, the interface where the two optics meet changes shape, thereby altering the refractive power of the lens system.

Abstract: The present invention is generally directed to accommodative intraocular lenses (IOLs) that exhibit a dynamic spherical aberration as a function of accommodative power. By way of example, in one aspect, the present invention provides an intraocular lens (IOL) having an anterior optical element, a posterior optical element, and a mechanism for coupling the anterior and posterior elements so as to allow axial movement of those elements relative to one another for providing accommodation when the lens is implanted in a patient's eye. Each of the anterior and the posterior elements includes at least one aspherical surface, where the asphericities of the surfaces are adapted to provide a combined spherical aberration that varies with accommodation.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and a weakened portion connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: Devices, systems, and methods useful in treating an eye are provided herein. Certain embodiments of the devices, systems, and methods may be particularly suitable in maintaining separation of an anterior capsule and a posterior capsule of an evacuated lens capsule of an eye. Certain embodiments of the devices, systems, and methods may be particularly suitable for reducing scarring in the visual field of an eye having a capsulorhexis, among other things.

Abstract: Intraocular devices for use in and attached to the natural lens capsule of an eye are provided. The lens capsule may be maintained in a configuration to avoid post-operative changes that are deleterious to vision. Single or dual optic systems are provided, which may be accommodating. Combinations of devices to obtain dual optic systems are disclosed.

Abstract: An IOL having an optic and a peripheral stabilizing ring. The optic and the ring are connected by a flexible bridge. An area on the ring coinciding with a feature on the optic helps to locate the optic within the ring in an unstressed state until the capsular bag collapses and locks the optic into place.

Abstract: An accommodating intraocular lens comprising a flexible body and flexible optic, and a flexible skirt connecting the optic to the body. The body may have extending loop haptics.

Abstract: An intraocular lens for insertion into the capsular bag of an eye contains an optic, an outer periphery, and an outer support structure. The optic has a periphery and centered about an optical axis. The outer periphery is disposed about the optic and configured to engage an equatorial region of the capsular bag of an eye. The outer support structure is disposed along the periphery and spaced from the optic with voids outer support structure and the optic. The intraocular lens further comprises a first intermediate member and a weakened region disposed along the outer periphery between the outer support structure and the first intermediate member. The first intermediate member operably couples the optic and the outer support structure. The weakened region is attached to, and configured to provide relative motion between, the outer support structure and the first intermediate member in response to the ciliary muscle of the eye.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and hinged portions longitudinally connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: Disclosed is an intraocular lens that is inserted inwardly into a capsular sac. One embodiment of the present invention provides an intraocular lens inserted inwardly into a capsular sac including an optic portion including a first optic body whose central region has a smaller thickness than a circumference of the central region and a second optic body coupled to the first optic body and whose central region has the same or higher thickness as/than the first optic body; and a haptic portion including a connection bar coupled to the optic portion and first support bar coupled to a circumference of the connection bar to be in contact with an inner surface of the capsular sac.

Abstract: A two or three component lens system. The first component is a ring-like supporting component that is implanted in the capsular bag following cataract surgery. The first component is a non-optical component and does not correct for any refractive errors. The first component may contain features to help reduce or eliminate PCO. The second component is an optical component that may contain all of the corrective optical power of the lens system. The second component has a pair of tabs for locking the second component within the first component. The first component includes a feature that allows the surgeon to change the position of the second component along the optical axis of the lens system. The third component is optional and is similar to second component and contains some optical power to correct for any residual optical error not corrected by the second component. The second and third components may also be implanted so as to move relative to one another, thereby providing some accommodation.