Material Characteristic Patents (Class 623/924)

Cross-Reference Art Collections

Natural (Class 623/925)
  • Patent number: 11396690
    Abstract: A method of producing medically applicable nanostructured titanium with improved mechanical properties includes performing an equal-channel angular pressing (ECAP) and subsequently performing a surface mechanical attrition treatment (SMAT). By performing the ECAP processing on a titanium sample, an ultrafine grained structure is obtained. The ultrafine grained structure may improve the biocompatibility and mechanical properties of pure titanium. When the SMAT processing is performed on the ultrafine grained structure, a nanostructured surface may be obtained. The SMAT processing may be used to enhance the strength of pure titanium to be used in medically applicable implants.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: July 26, 2022
    Assignee: Prince Mohammad Bin Fahd University
    Inventor: Faramarz Djavanroodi
  • Patent number: 8778262
    Abstract: One aspect is an alloy consisting of niobium, zirconium, tantalum, and tungsten. The alloy is formed with a melt metallurgical route such that all four metals solidify as a homogeneous alloy having no inclusions more than 10 ?m in size.
    Type: Grant
    Filed: March 1, 2013
    Date of Patent: July 15, 2014
    Assignee: Heraeus Precious Metals GmbH & Co. KG
    Inventors: Herwig Schiefer, Christoph Vogt, Heiko Specht, Jens Troetzschel
  • Patent number: 8591672
    Abstract: The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: November 26, 2013
    Assignee: Bio DG, Inc.
    Inventors: Gordon F. Janko, Herbert R. Radisch, Thomas A. Trozera
  • Patent number: 8343212
    Abstract: A medical device, for example a stent, has a surface which in use contacts body tissue, wherein said surface has on it a biocompatible coating layer comprising a polymer having covalently bound allyl-terminated pendent groups, said pendent groups comprising a moiety selected from -0-CH2—CH?CH2—S—CH2—CH?CH2—S(=0)-CH2—CH?CH2—Se—CH2—CH?CH2 and —Se (=0 J-CH2—CH?CH2. This surface has good biocompatibility and can bind strongly to a metallic surface. The polymer may be made from an electropolymerisable monomer, e.g. a pyrrole.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: January 1, 2013
    Assignee: Biotectix, LLC
    Inventors: Christopher John Pickett, Timothy James Boote, Saad Khalil Ibrahim, Jane Marie Knott, John Douglas Tolland
  • Patent number: 8246762
    Abstract: The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: August 21, 2012
    Assignee: Bio DG, Inc.
    Inventors: Gordon F. Janko, Herbert R. Radisch, Jr., Thomas A. Trozera
  • Patent number: 8057914
    Abstract: A method of fabricating a medical implant component. The method may comprise producing a substrate from a first material in which the substrate has a bearing portion, and causing particles of a second material to be formed onto at least the bearing portion of the substrate. The second material may be formed from a biocompatible material and a carbide source, in which the carbide source is 6.17% or more of the second material by weight. The particles of the second material may be formed onto at least the bearing portion of the substrate by a predetermined spraying technique, a CVD process, a PVD process, or a carburization process. The biocompatible material may be cobalt chrome and the carbide source may be graphite.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: November 15, 2011
    Assignee: Howmedica Osteonics Corp.
    Inventors: Daniel E. Lawrynowicz, Aiguo Wang, Zongtao Zhang
  • Patent number: 8002909
    Abstract: Alloy compositions suitable for fabricating medical devices, such as stents, are disclosed. In certain embodiments, the compositions have small amounts of nickel, e.g., the compositions can be substantially free of nickel.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: August 23, 2011
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Charles Horace Craig
  • Patent number: 7780798
    Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The endoprostheses comprise a tubular member capable of maintaining patency of a bodily vessel. The tubular member includes a mixture of at least two compositions, where the presence of the second composition gives the mixture a greater hardness than that of the first composition alone. The first composition includes less than about 25 weight percent chromium, less than about 7 weight percent molybdenum, from about 10 to about 35 weight percent nickel, and iron. The second composition is different from the first and is present from about 0.1 weight percent to about 5 weight percent of the mixture.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: August 24, 2010
    Assignees: Boston Scientific Scimed, Inc., CRS Holdings, Inc.
    Inventors: Jonathan S. Stinson, Matthew Cambronne, Richard B. Frank, Richard A. Gleixner, James E. Heilmann
  • Patent number: 7601230
    Abstract: Alloy compositions suitable for fabricating medical devices, such as stents, are disclosed. In certain embodiments, the compositions have small amounts of nickel, e.g., the compositions can be substantially free of nickel.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: October 13, 2009
    Assignee: Scimed Life Systems, Inc.
    Inventor: Charles Horace Craig
  • Patent number: 7510866
    Abstract: A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).
    Type: Grant
    Filed: October 29, 2003
    Date of Patent: March 31, 2009
    Assignee: Korea Institute of Science and Technology
    Inventors: Kuiwon Choi, Tae Soo Bae, Jung Kyu Kim, Chang Yang Lee
  • Patent number: 7128758
    Abstract: A medical device for use within a body lumen that is made from a binary nickel-titanium alloy that remains in its austenitic phase throughout its operational range is disclosed. The medical device, such as an intraluminal stent, is made from superelastic nickel-titanium and may optionally be alloyed with a ternary element. By adding the ternary element and/or through heat treatment, it is possible to lower the phase transformation temperature between the austenitic phase and the martensitic phase of the nickel-titanium alloy. By lowering the phase transformation temperature, the martensite deformation temperature is likewise depressed. It is possible then to depress the martensite deformation temperature below body temperature such that when the device is used in a body lumen for medical treatment, the nickel-titanium device remains completely in the austenitic phase without appearance of stress-induced martensite even if the device is placed under stress.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: October 31, 2006
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Daniel L. Cox
  • Patent number: 6854172
    Abstract: A process for producing implants made of a bioresorbable metal, particularly magnesium alloys or zinc alloys, in which the material properties of the magnesium or the zinc are changed and the processing and utilization properties are improved by combining process steps for adjusting the properties of the material and subsequent machining. In this way it is possible to produce thin-walled tubular implants, particularly blood vessel support stents, from bioresorbable magnesium or zinc alloys, which are readily deformable without the risk of fracture during implantation.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: February 15, 2005
    Assignee: Universitaet Hannover
    Inventors: Volker Kaese, Arne Pinkvos, Heinz Haferkamp, Matthias Niemeyer, Friedrich-Wilhelm Bach
  • Patent number: 6838174
    Abstract: An object is provided, which has a portion to be in contact with a human's skin when used, and can suppress irritation of the human's skin. A skin-contact portion of the object to be in contact with the human's skin when used is coated with a carbon film. For example, the carbon-film-coated object is glasses having ear pieces of temples and node pads coated at least partially with carbon films having a function of suppressing skin irritation.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: January 4, 2005
    Assignee: Nissan Electric Co., Ltd.
    Inventor: Takahiro Nakahigashi
  • Publication number: 20040158309
    Abstract: The present invention relates to a medical device or implant made at least in part of a high strength, low modulus metal alloy comprising Niobium, Tantalum, and at least one element selected from the group consisting of Zirconium, Tungsten, and Molybdenum. The medical devices according to the present invention provide superior characteristics with regard to bio-compatibility, radio-opacity and MRI compatibility.
    Type: Application
    Filed: April 8, 2003
    Publication date: August 12, 2004
    Applicant: W. C. Heraeus GmbH & Co. KG
    Inventors: Jurgen Wachter, Jens Trotzschel
  • Patent number: 6712850
    Abstract: The present invention is a synthetic, biocompatible, bioabsorbable, porous foam tissue scaffolds possessing physicochemical properties suitable for use in the repair and regeneration of dermal tissue and to methods of preparing the foam scaffold.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: March 30, 2004
    Assignee: Ethicon, Inc.
    Inventors: Murty Narayan Vyakarnam, Mark Charles Zimmerman, Anna Gosiewska
  • Patent number: 6626937
    Abstract: A medical device for use within a body lumen that is made from a binary nickel-titanium alloy that remains in its austenitic phase throughout its operational range is disclosed. The medical device, such as an intraluminal stent, is made from superelastic nickel-titanium and may optionally be alloyed with a ternary element. By adding the ternary element and/or through heat treatment, it is possible to lower the phase transformation temperature between the austenitic phase and the martensitic phase of the nickel-titanium alloy. By lowering the phase transformation temperature, the martensite deformation temperature is likewise depressed. It is possible then to depress the martensite deformation temperature below body temperature such that when the device is used in a body lumen for medical treatment, the nickel-titanium device remains completely in the austenitic phase without appearance of stress-induced martensite even if the device is placed under stress.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: September 30, 2003
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Daniel L. Cox
  • Patent number: 6579313
    Abstract: A method for implanting cells onto a prosthesis includes the steps of: (a) providing a prosthesis including a porous tube, where at least 25% of the pores on the inner surface of the tube have diameters of more than about 40 &mgr;m, at least 25% of the pores on the outer surface of the tube have diameters of less than about 30 &mgr;m, and the tube includes a substantially continuous layer of a biocompatible material; (b) contacting the prosthesis with a suspension of cells; and (c) providing a pressure differential between the inner surface and the outer surface, whereby the cells are retained in the pores of the inner surface. A method for obtaining an endothelial cell culture from a blood sample involved:(a) obtaining a sample for mononuclear cells from a blood sample; and (b) culturing the sample of mononuclear cells, without further cell separation, on a cell adhesive polymer-coated solid support in the presence of endothelial growth factors.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: June 17, 2003
    Assignee: The Bringham and Women's Hospital
    Inventors: Victor J. Dzau, Richard E. Pratt, Michael J. Mann, Afshin Ehsan, Daniel P. Griese
  • Publication number: 20030018380
    Abstract: A platinum enhanced radiopaque alloy particularly suitable for manufacture of implantable and/or intravascular medical devices. A stent is one preferred medical device which is a generally tubular structure that is expandable upon implantation in a vessel lumen to maintain flow therethrough. The stent is formed from the alloy which has improved radiopacity relative to present utilized stainless steel alloys. This alloy preferably contains from about 2 wt. % to about 50 wt. % platinum; from about 11 wt. % to about 18 wt. % chromium; about 5 wt. % to about 12 wt. % nickel and at least about 15 wt. % iron.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 23, 2003
    Inventors: Charles H. Craig, Herbert R. Radisch, Thomas A. Trozera, David M. Knapp, Timothy S. Girton, Jonathan S. Stinson
  • Patent number: 6399215
    Abstract: We disclose ultrafine-grained titanium. A coarse-grained titanium billet is subjected to multiple extrusions through a preheated equal channel angular extrusion (ECAE) die, with billet rotation between subsequent extrusions. The resulting billet is cold processed by cold rolling and/or cold extrusion, with optional annealing. The resulting ultrafine-grained titanium has greatly improved mechanical properties and is used to make medical implants.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: June 4, 2002
    Assignee: The Regents of the University of California
    Inventors: Yuntian T. Zhu, Terry C. Lowe, Ruslan Z. Valiev, Vladimir V. Stolyarov, Vladimir V. Latysh, Georgy J. Raab
  • Patent number: 6267921
    Abstract: The invention concerns a high specification non-magnetic stainless steel which is corrosion resistant in physiological media and which can be produced at atmospheric pressure, characterized in that its composition in % by weight is as follows: Mn 15% to 24% Ti ≦0.020% Cr 15% to 20% Al ≦0.020% Mo 2.5% to 4% S ≦0.0020% N 0.6% to 0.85% B ≦0.020% V 0.1% to 0.5% Nb + Ta ≦0.5% C ≦0.06% Co ≦0.5% Ni ≦0.25% Cu ≦0.5% silica ≦0.25% and from 0 to 0.5% of each of elements Cu, Co and of the sum Nb+Ta, the remainder being constituted by iron and impurities, and in that its composition satisfies the following conditions: (%Cr)+2.5(%Mo)≦27  (I) (%Cr)+3.3(%Mo)≧26  (II); and Log(%N)+0.0605(%N)=−1.3+[125(%V)+80(%Nb)+52(%Cr)+19(%Mn)]×10−3−[4.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: July 31, 2001
    Assignee: Societe Industrielle de Metallurgie
    Inventors: Jacques Montagnon, Jean-Yves Moraux