With Spectrometer Patents (Class 73/23.37)
  • Patent number: 10663439
    Abstract: An analysis method for a substance to be measured, including (a) introducing a sample into a flow channel having a bypass, flow channel and introducing the sample introduced into the bypass flow channel into a measuring device so as to measure signal intensity or concentration of a substance to be measured and/or a carrier in the sample; (b) introducing a sample that has not been introduced into the bypass flow channel into a column so as to adsorb the substance to be measured and/or the carrier; and (c) introducing an eluate into the column, eluting the substance to be measured and/or the carrier adsorbed on the column, and introducing the substance and/or the carrier into the measuring device so as to measure the signal intensity or concentration of the eluted substance to be measured and or the carrier.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: May 26, 2020
    Assignees: PerkinElmer Japan Co., Ltd., National University Corporation Fukushima University
    Inventors: Makoto Furukawa, Yoshitaka Takagai
  • Patent number: 9932825
    Abstract: Wellbore tools in accordance with the present disclosure may include a gas chromatograph; and a mass spectrometer, wherein the mass spectrometer is configured to operate at a pressure greater than 10?2 Torr. Systems in accordance with the present disclosure may include a gas chromatograph; and a mass spectrometer, wherein the mass spectrometer is configured to operate at a pressure greater than 10?2 Torr. Methods in accordance with the present disclosure may include emplacing a wellbore tool in a wellbore, the wellbore tool containing a gas chromatograph and a mass spectrometer, wherein the mass spectrometer is configured to operate at a pressure greater than 10?2 Torr; drawing a sample of a fluid from the wellbore into the wellbore tool; and determining a molecular weight of one or more components of the fluid.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: April 3, 2018
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Ronald E. G. van Hal, Albert Ballard Andrews, Jeffrey Crank
  • Patent number: 9789434
    Abstract: The present disclosure is directed to methods and systems for detecting a substance in a sample gas. The methods and systems include separating the substance of interest in the sample gas, and introducing the separated sample gas into a detector. The systems and methods further include performing an analysis of the substance of interest.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: October 17, 2017
    Assignee: Morpho Detection, LLC
    Inventors: Hanh T. Lai, Vibha Mishra, Wilhelm P. Platow
  • Patent number: 9696290
    Abstract: The interior of a fractionating tool for fractionating dioxins is packed with a purification layer and an adsorption layer. The adsorption layer includes a first adsorption layer including an activated carbon-containing silica gel layer and a graphite-containing silica gel layer, and a second adsorption layer including an alumina layer. When a solution of dioxins is injected into the purification layer and is supplied with an aliphatic hydrocarbon solvent, the solvent dissolves dioxins in the solution of dioxins and passes through the purification layer and the adsorption layer. In this process, non-ortho PCBs, PCDDs and PCDFs among dioxins are adsorbed to the first adsorption layer, and mono-ortho PCBs among dioxins are adsorbed to the second adsorption layer. As a result, dioxins are fractionated into a group including non-ortho PCBs, PCDDs and PCDFs, and mono-ortho PCBs.
    Type: Grant
    Filed: May 27, 2013
    Date of Patent: July 4, 2017
    Assignee: MIURA CO., LTD.
    Inventors: Hiroyuki Fujita, Hirofumi Nakamura
  • Patent number: 9463534
    Abstract: A column-sealing tool is provided for use during decoupling of a capillary column from a gas chromatography-mass spectrometry (CG-MS) system. The column-sealing tool includes an engagement structure for removably securing the column-sealing tool within a high vacuum enclosure of the GC-MS system, at a location between a high vacuum end of a transfer line and a mass analyzer of the GC-MS system. Additionally, the column-sealing tool includes a sealing element that is actuatable between a non-sealing position and a sealing position. During use the sealing element forms a secondary vacuum seal with the first end of the transfer line when the column-sealing tool is inserted into the GC-MS system and when the sealing element is in the sealing position.
    Type: Grant
    Filed: July 29, 2014
    Date of Patent: October 11, 2016
    Assignee: Thermo Finnigan LLC
    Inventors: James M. Hitchcock, George B. Guckenberger
  • Patent number: 9188572
    Abstract: A liquid chromatograph analyzing device, which without an analyst having to set complicated processing conditions before measuring a sample, is able to processes unaffected by fluctuations in room temperature and appearance of ghost peaks. In a liquid chromatograph analyzing device, an automatic sampler, a liquid sending pump, a column oven and a detection device are controlled by a calculation processing device. In addition to chromatograph creation unit, which creates chromatograms of a sample based on input detection signals, the calculation processing device has a correction parameter holding section and correction formula setting unit. The correction formula setting unit provides to the liquid chromatograph analyzing device a functionality for the analyst to set correction formulas for incorporating in the chromatograms created by the chromatograph creation unit changes to environmental conditions such as fluctuations in temperature around the liquid chromatograph analyzing device.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: November 17, 2015
    Assignee: Shimadzu Corporation
    Inventor: Takafumi Nakamura
  • Patent number: 9075073
    Abstract: For the detection and structural analysis of cathinone-based compounds subject to comprehensive regulation, three MS/MS measurements are repeated for a target sample: an MRM measurement; a product-ion scan measurement; and a product-ion scan measurement. Based on the positional coincidence of a peak on chromatograms obtained by the three measurements, non-cathinone-based compounds are excluded. From the MRM transition and the product-ion spectrum pattern, the kinds of functional groups are estimated and the structure of the cathinone-based compound is estimated.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: July 7, 2015
    Assignee: SHIMADZU CORPORATION
    Inventors: Yuki Sakamoto, Haruhiko Miyagawa
  • Publication number: 20150121993
    Abstract: The dispersive liquid-liquid microextraction (DLLME) method of detecting N-nitrosoamines (NAs) is a DLLME performed with a xylene extraction solvent and a methanol disperser solvent. The microextraction is preferably performed by a programmable array logic (PAL) auto-sampler. Determination and measurement of concentration of the NAs in the water sample being found by a gas chromatograph coupled with a mass spectrometer (GC-MS).
    Type: Application
    Filed: November 5, 2013
    Publication date: May 7, 2015
    Applicants: KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY, KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventors: CHANBASHA BASHEER, MOUSA YASIR MOUSA AMAYREH
  • Patent number: 9021861
    Abstract: A heatable flow-through measuring cell for a gas analyzer having an inner tube made of a corrosion-resistant material, such as stainless steel, and is terminated at each end with a respective end piece and a radiolucent window held therein. The measuring cell also includes an electrical heating apparatus for heating each end piece, an outer tube that coaxially surrounds the inner tube so as to form a narrow gap and is made of material with good thermal conductivity, such as aluminum, and includes thermal insulation that surrounds the outer tube.
    Type: Grant
    Filed: June 16, 2010
    Date of Patent: May 5, 2015
    Assignee: Siemens Aktiengesellschaft
    Inventor: Michael Ludwig
  • Publication number: 20150107331
    Abstract: Petroleum or other hydrocarbon samples can be analyzed in parallel by 1) GC-field ionization Time of Flight Mass Spectrometer (GC-FI-TOF MS) and 2) two dimensional gas chromatography (2D-GC) equipped with a flame ionization detector (FID). The combined techniques allow for improved quantitative characterization of the compounds within a hydrocarbon sample. The techniques can be combined by correlating the 2D-GC FID data with the GC-FI-TOF MS data based on correlation of compound classes, correlation of retention windows within a compound class, correlation of individual compounds, such as paraffins, or a combination thereof.
    Type: Application
    Filed: October 23, 2013
    Publication date: April 23, 2015
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Frank C. WANG, Kuangnan QIAN, Kathleen E. EDWARDS
  • Publication number: 20150096349
    Abstract: A non-specific gas analyzer with a wide dynamic range of concentration is used to assess the gas sample for total load of volatile organic constituents, and then control either a dilution with neutral gas or the quantity of sample aspirated in order to consistently deliver an appropriate total load of volatile analyte to a high-sensitivity analyzer. Such high-sensitivity analyzers may be gas chromatography combined with mass spectrometry or related mass spectrometry configurations, such as selected ion flow tube mass spectrometry, gas chromatography combined with ion mobility spectrometry, or related ion mobility configurations such as differential mobility spectrometry.
    Type: Application
    Filed: April 14, 2013
    Publication date: April 9, 2015
    Inventor: Royce W. Johnson
  • Publication number: 20150068279
    Abstract: The electro-enhanced solid-phase microextraction (EE-SPME) method involves extraction that is performed with an SPME fiber, preferably made of polydimethylsiloxane (PDMS), in the presence of an applied electric potential for a predetermined period of time. Polar analytes are extracted onto the fiber, which is the stationary phase. The solid-phase microextraction fiber is then inserted into an injection port of a gas chromatograph coupled with a mass spectrometer. The polar analytes are desorbed in the injection port, and are analyzed by GC-MS to detect and quantify the individual components.
    Type: Application
    Filed: September 11, 2013
    Publication date: March 12, 2015
    Applicants: KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY, KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
    Inventors: CHANBASHA BASHEER, MOUSA YASER MOUSA AMAYREH
  • Publication number: 20150059439
    Abstract: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device configured to provide three-way switching or switching between three or more inputs or outputs. The microfluidic device can be fluidically coupled to one or more switching valves to provide for selective control of fluid flow in the chromatography system.
    Type: Application
    Filed: August 4, 2014
    Publication date: March 5, 2015
    Inventor: Andrew Tipler
  • Publication number: 20150059440
    Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.
    Type: Application
    Filed: November 11, 2014
    Publication date: March 5, 2015
    Inventors: Dale A. Harrison, Anthony T. Hayes, Phillip Walsh
  • Patent number: 8895916
    Abstract: In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: November 25, 2014
    Assignee: Ionsense, Inc.
    Inventor: Brian D Musselman
  • Patent number: 8883508
    Abstract: In some embodiments, apparatus and systems, as well as methods, may operate to draw a formation fluid sample into a sampling port included in a down hole tool, to vaporize some part of the fluid sample to substantially fill an injection port with a gas phase, to differentiate gas components in the gas phase to provide differentiated gas components along a concentration gradient, to detect the differentiated gas components, and to determine a fingerprint of the differentiated gas components. Other apparatus, systems, and methods are disclosed.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: November 11, 2014
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Christopher M. Jones, Michael T. Pelletier
  • Publication number: 20140326043
    Abstract: An energy store, in particular to a lithium-based energy store. In order to make a simple and exact determination of a state of health, e.g., the aging condition, possible, the energy store includes at least one cell having an anode, a cathode, and an electrolyte which is situated between the anode and the cathode, at least one cell having an outlet for conveying functional material from the cell to an analysis unit and the outlet being connectable to the analysis unit in a fluid-tight manner. Also described is a system including the energy store and an analysis unit, and a method for ascertaining a state of health of an energy store.
    Type: Application
    Filed: July 17, 2012
    Publication date: November 6, 2014
    Inventors: Marcus Wegner, Jens Grimminger, Martin Tenzer, Jean Fanous
  • Patent number: 8841611
    Abstract: A gas chromatograph-mass spectrometer (GC-MS) system includes a multi-capillary GC column coupled to a mass analyzer through an ionization interface. The ionization interface includes an ionization device and an ion guide configured for receiving a high-capacity gas-sample flow from the GC column and transmitting a compressed ion beam to the mass analyzer. The ion beam may be converging.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: September 23, 2014
    Assignee: Agilent Technologies, Inc.
    Inventors: Gangqiang Li, Maozi Liu
  • Publication number: 20140260535
    Abstract: A chemical detector for rapid, simultaneous detection of multiple chemicals including chemical warfare agents, toxic industrial chemicals, and explosives having one or more gas chromatography columns each with a chemosorbent or a chemo-reactive stationary phase and an infrared-transparent base, a bright infrared light source, a mechanism to direct the light source to any point along any of the columns, and an infrared sensor. Another disclosed detector has one or more gas chromatography columns each on the surface of a substrate having at least one infrared-transparent waveguide pattern, a bright infrared light source, and at least one ring resonator for each column, where each ring resonator is coated with a chemosorbent or a chemo-reactive stationary phase, and where each ring resonator spectroscopically probes the stationary phase. Also disclosed are the related methods for chemical detection.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Inventors: R. Andrew McGill, Robert Furstenberg, Viet K. Nguyen, Chris Kendziora, Michael Papantonakis, Todd H. Stievater
  • Publication number: 20140260536
    Abstract: A system includes a gas chromatograph configured to determine experimental chromatographic data including retention times associated with samples. The system also includes a mass spectrometer configured to determine experimental mass spectral data associated with samples. The mass spectrometer can include a quadrupole field ion trap that uses a non-classical detection technique. The system. determines a retention index for an unknown sample based upon retention times for a calibration sample and the unknown sample, and identifies reference mass spectral data using the retention index. The reference mass spectral data can include spectra measured using a classical detection technique. The system can compare the experimental mass spectral data to the reference mass spectral data using one or more comparison metrics, such as a percent fragment match and/or a variance match. A score can be determined to identify the unknown sample using one or more of the metrics.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Smiths Detection Inc.
    Inventors: Charles S. Sadowski, Greger Andersson, Kevin Judge
  • Publication number: 20140250977
    Abstract: A mass spectrometer for analyzing a sample may include an analysis chamber for analyzing the sample and a first vacuum pump operably connected to the analysis chamber, wherein the first vacuum pump operates to create a first vacuum state. The mass spectrometer may also include a sample-preparation chamber operably connected to the analysis chamber and a second vacuum pump that operates to create a second vacuum state, wherein the first vacuum state is a lower pressure than the second vacuum state. The second vacuum pump may be operably connected to the first vacuum pump in a first configuration, and the second vacuum pump may be operably connected to the sample-preparation chamber in a second configuration.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 11, 2014
    Applicant: 1st Detect Corporation
    Inventors: Michael Spencer, Warren Mino, David Rafferty
  • Publication number: 20140216133
    Abstract: A method in which a sample of a gas mixture to be analyzed via gas chromatography is conducted through a chromatographic separating device via a carrier gas, separated components of the gas mixture are subsequently quantitatively determined in an absorption spectrometer having a wavelength-adaptable light source, and in order to increase the speed of analysis and to be able to also determine components that cannot be measured via absorption spectroscopy, the wavelength of the light source can be adapted to an absorption line of the carrier gas, where the individual components of the gas mixture are determined indirectly via a concentration reduction of the carrier gas.
    Type: Application
    Filed: June 26, 2012
    Publication date: August 7, 2014
    Inventor: Piotr Strauch
  • Publication number: 20140192343
    Abstract: An efficient absorption spectroscopy system is provided. The spectroscopy system may be configured to measure solid, liquid or gaseous samples. Vacuum ultra-violet wavelengths may be utilized. Some of the disclosed techniques can be used for detecting the presence of trace concentrations of gaseous species. A preferable gas flow cell is disclosed. Some of the disclosed techniques may be used with a gas chromatography system so as to detect and identify species eluted from the column. Some of the disclosed techniques may be used in conjunction with an electrospray interface and a liquid chromatography system so as to detect and identify gas phase ions of macromolecules produced from solution. Some of the disclosed techniques may be used to characterize chemical reactions. Some of the disclosed techniques may be used in conjunction with an ultra short-path length sample cell to measure liquids.
    Type: Application
    Filed: March 11, 2013
    Publication date: July 10, 2014
    Applicant: VUV ANALYTICS, INC.
    Inventor: VUV ANALYTICS, INC.
  • Patent number: 8729496
    Abstract: In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 20, 2014
    Assignee: Ionsense, Inc.
    Inventor: Brian D. Musselman
  • Publication number: 20140116112
    Abstract: Methods are provided for rapidly determining the presence or absence of large numbers of contaminants in a test sample, such as a raw material intended for use in the preparation of a nutraceutical. The disclosed methods employ gas chromatography-mass spectrometry techniques together with the specific use of software in combination with a database to analyze data collected after ionization of the sample and determine the presence or absence of the contaminants in the sample.
    Type: Application
    Filed: March 14, 2013
    Publication date: May 1, 2014
    Applicant: K & D LABORATORIES, INC.
    Inventors: David Kent HUMPHREY, Nicholas Joseph GEISE
  • Publication number: 20140116111
    Abstract: A gas chromatograph mass spectrometer including: an oven for gas chromatography, a mass spectrometry part, a sample vaporization chamber, a gas supply part, and a control part. When the replacement operation of a septum or a glass insert begins, the control part controls the gas supply part so that the flow rate of a carrier gas has a constant pressure and then controls heaters so that temperature is equal to or less than a temperature at which replacement is possible. When temperature becomes equal to or less than the temperature at which replacement is possible and the replacement operation of the septum or the glass insert is completed, the control part controls the heaters so that the temperature is an analysis temperature and controls the gas supply part to employ the same control method for the flow rate of the carrier gas as that before the replacement operation is begun.
    Type: Application
    Filed: October 26, 2012
    Publication date: May 1, 2014
    Applicant: SHIMADZU CORPORATION
    Inventors: Katsuyuki TANEDA, Shuichi KAWANA
  • Publication number: 20140069167
    Abstract: A device is provided for delivering gases to an analyzer, such as an isotopic ratio mass spectrometer. The device includes first and second reactors, preferably arranged in parallel. At least one of the reactors may be selectively activated, or means may be incorporated to circumvent one of the reactors, such that different types of gas conversions may be achieved.
    Type: Application
    Filed: November 11, 2013
    Publication date: March 13, 2014
    Applicant: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Michael KRUMMEN, Hans-Juergen SCHLUETER
  • Publication number: 20140020447
    Abstract: In the method of latent print analysis, wherein the improvement comprises using an ultra-fine, nanoporous carbon material as an adsorptive powder to identify trace chemicals found within oils of a print.
    Type: Application
    Filed: March 14, 2013
    Publication date: January 23, 2014
    Applicant: BAE Systems Information and Electronic Systems Integration Inc.
    Inventor: BAE Systems Information and Electonic Systems Integration Inc.
  • Publication number: 20140000341
    Abstract: A method of operating a gas chromatograph-mass spectrometer (GC-MS) comprising a GC column for separating analytes of a sample, a GC oven and a mass spectrometer comprises: providing a conduit extending between the GC oven and the mass spectrometer such that a conduit interior volume is contiguous with an interior volume of the GC oven; routing the GC column through the GC oven and conduit interior volume to an ion source of the mass spectrometer; providing a flow of temperature regulated air or gas between a fan or blower of the gas chromatograph and the conduit interior volume; introducing the sample into the GC column; controlling the temperature of the GC oven interior volume and the conduit interior volume so as to facilitate analyte separation within the GC column and transfer of the separated analytes to the mass spectrometer; and analyzing the separated analytes with the mass spectrometer.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 2, 2014
    Applicant: Thermo Finnigan LLC
    Inventor: Edward B. McCauley
  • Patent number: 8613214
    Abstract: An apparatus and method to determine analytes in a fluid. One aspect of the present invention is for the determination of the oil content of water using UV, near-IR, IR or Raman spectroscopy or radiometry. In certain embodiments, a solid membrane material absorbs analytes from fluid brought into contact with it. The membrane is subsequently placed in a FTIR spectrometer, which spectrometer is enabled to determine the concentration of analytes in fluid by calibration. Certain embodiments can determine the type of hydrocarbon present, and thus can differentiate Total Petroleum Hydrocarbons (TPH) from Total Oil and Grease (TOG), without any separate sample preparation.
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: December 24, 2013
    Assignee: Orono Spectral Solutions, Inc.
    Inventors: Tyler P. Martin, Luke Doucette, Dean J. Smith, Thomas P. Schwarz
  • Patent number: 8592755
    Abstract: A method of operating a switching valve of a GC-MS apparatus is provided with installing a sample injector; connecting a first capillary column downstream of the sample injector; installing a heart-cutting unit downstream of the first capillary column; installing a first interconnecting column and a second capillary column to the heart-cutting unit respectively; connecting a switching valve to the heart-cutting unit via a first interconnecting column and a second capillary column respectively wherein the switching valve includes a plurality of ports; connecting the switching valve to an MS via a second interconnecting column; and switching ports to create different sample loops for passing compounds from the heart-cutting unit to the MS or passing compounds from the heart-cutting unit to the discharge column to be purged.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: November 26, 2013
    Assignee: China Tobacco Fujian Industrial Co., Ltd.
    Inventors: Hongliang Lu, Kai Lin, Jing Yu, Feng Zhang
  • Publication number: 20130305596
    Abstract: The present disclosure includes liquid compositions that can be used for marking liquid hydrocarbon-based fuels and combustibles; these compositions include at least one marker, one or more solvents and, optionally, one or more functional additives other than the markers. The disclosure also includes a process for qualitative and quantitative detection of these markers present in a liquid hydrocarbon-based composition.
    Type: Application
    Filed: February 7, 2012
    Publication date: November 21, 2013
    Applicant: TOTAL MARKETING SERVICES
    Inventors: Bénédicte Amblard, Denis Fadel, Jean-Paul Mercier, Frédéric Tort, Christian Tremoliere
  • Patent number: 8578755
    Abstract: A device is provided for delivering gases to an analyzer, such as an isotopic ratio mass spectrometer. The device includes first and second reactors, preferably arranged in parallel. At least one of the reactors may be selectively activated, or means may be incorporated to circumvent one of the reactors, such that different types of gas conversions may be achieved.
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: November 12, 2013
    Assignee: Thermo Fisher Scientific (Bremen) GmbH
    Inventors: Michael Krummen, Hans-Juergen Schlueter
  • Patent number: 8563945
    Abstract: In various embodiments of the invention, a cargo container can be monitored at appropriate time intervals to determine that no controlled substances have been shipped with the cargo in the container. The monitoring utilizes reactive species produced from an atmospheric analyzer to ionize analyte molecules present in the container which are then analyzed by an appropriate spectroscopy system. In an embodiment of the invention, a sorbent surface can be used to absorb, adsorb or condense analyte molecules within the container whereafter the sorbent surface can be interrogated with the reactive species to generate analyte species characteristic of the contents of the container.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: October 22, 2013
    Assignee: Ionsense, Inc.
    Inventor: Brian D. Musselman
  • Patent number: 8549893
    Abstract: A system for interfacing a gas chromatograph (GC) to a mass spectrometer the GC comprising a GC column partially contained within a GC oven, the mass spectrometer comprising a housing enclosing an interior having an ion source, the system comprising: a conduit extending from the GC oven to the mass spectrometer and comprising an interior volume that is contiguous with an interior volume of the GC oven; and a duct extending from a region of relatively high or relatively low pressure within the GC oven to the conduit interior volume and operable so as to transmit a flow of air or gas between the region of relatively high or relatively low pressure and the conduit interior volume, wherein a portion of the GC column extends through the conduit interior volume to the ion source.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: October 8, 2013
    Assignee: Thermo Finnigan LLC
    Inventor: Edward B. McCauley
  • Publication number: 20130256523
    Abstract: A transfer line for conveying the column effluent from a gas chromatograph to an ion source of a mass spectrometer has a transfer line body and a mechanism for moving the transfer line body either towards or away from the mass spectrometer. A gas seal between the housing of the mass spectrometer and the transfer line body prevents vacuum leak when the transfer line body is moved. In one embodiment, the transfer line body outer periphery is threaded and a hand wheel engages the transfer line body threads via complementary threads in order to move the body. When the transfer line is moved towards the mass spectrometer, the body presses an ion source, which is not rigidly fixed to the housing of the mass spectrometer, into a recess seat of the housing, and aligns the ion source in an operating position.
    Type: Application
    Filed: March 13, 2012
    Publication date: October 3, 2013
    Inventors: Urs Steiner, Felician Muntean, Bert D. Egley
  • Publication number: 20130233054
    Abstract: A system and method for improving operation of a needle trap by changing a flow path through a needle trap to enable a needle to draw a fluid sample into a working end of the needle and out through the side hole, wherein drawing the sample through the side hole eliminates the possibility of a leak through the side hole while drawing a fluid sample into the working end.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 12, 2013
    Applicant: TORION TECHNOLOGIES, INC.
    Inventors: Joseph L. Oliphant, Nathan Porter, Anthony D. Rands
  • Publication number: 20130219991
    Abstract: A method for the in-instrument recombination of volatiles using a gas chromatograph with mass spectrometry and olfactometry detection is described. Compounds that are introduced into the modified GC are separated conventionally on an analytical capillary GC column. The elution profile of volatiles can be segmented, analyzed and arbitrarily combined. In-line with the GC column, a pneumatic flow switch and splitter are connected to a detector and olfactometer. A cold trap allows the user to build a mixture of separated volatiles that is held until the cryotrap is rapidly heated, releasing the mixture for a subject to smell at the olfactory port and to evaluate. The instrument allows for characterization of the aroma quality of specific fractions of aroma volatiles obtained from foods, flowers or beverages without the need for pure chemical standards or the calculation of individual compound concentrations or sensory thresholds.
    Type: Application
    Filed: February 14, 2013
    Publication date: August 29, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: The Regents Of The University of California
  • Patent number: 8515685
    Abstract: A mass spectrometer and a method of spectrometry are disclosed wherein liquid chromatography mass spectral data are probabilistically clustered on the basis of mass to charge ratio and retention time.
    Type: Grant
    Filed: May 3, 2005
    Date of Patent: August 20, 2013
    Assignee: Micromass UK Limited
    Inventors: Richard Denny, Keith Richardson
  • Patent number: 8492152
    Abstract: Apparatus and systems, as well as methods, may operate to draw a formation fluid sample into a sampling port included in a down hole tool or tool body, to vaporize some part of the fluid sample to substantially fill an injection port with a gas phase, to differentiate gas components in the gas phase to provide differentiated gas components along a concentration gradient in a receiving section, to detect the differentiated gas components with a detector, and to determine a fingerprint of the differentiated gas components. A reaction section and a vacuum section may be used for waste consumption and/or absorption.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: July 23, 2013
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Christopher M. Jones, Michael T. Pelletier
  • Patent number: 8490466
    Abstract: The present invention includes a heat sealable capsule adapted for use in analysis devices such as GCs, and methods for using the capsules to perform analysis in such devices. The capsules include a tube having an end that is heat-sealed to contain a sample that is to be analyzed at an injection temperature. The tube includes a heat sealable medium having a heat seal that closes the end, the tube having an inner and outer surface, both of the surfaces being substantially chemically inert with respect to the sample. The tube is substantially free of any material that outgases at the injection temperature. The tube is openable without breaking into pieces, and remains intact at the injection temperature. The capsule can include a programmable tag that stores information related to the sample contained therein.
    Type: Grant
    Filed: December 20, 2009
    Date of Patent: July 23, 2013
    Assignee: Agilent Technologies, Inc.
    Inventors: Arthur Schleifer, Carl A. Myerholtz
  • Patent number: 8448493
    Abstract: A gas chromatograph-combustion apparatus and method are disclosed in which the carrier gas type and flow rate is continuously exchanged to facilitate high speed, high sensitivity compound specific isotope analysis. Samples are injected into a gas chromatograph that uses H2 as the carrier gas. The gas stream exiting the gas chromatograph is passed through a combustion system in which H2 and the samples are combusted, simultaneously and totally, to oxidize the sample to CO2 and/or N2 gas, and to convert H2 gas to water vapor. Water vapor is removed using a water separator. Therefore, combustion serves the dual purpose of preparing the samples for isotopic analysis and converting H2 to water vapor, which can be easily separated out. A second carrier gas may be used to convey the CO2 and N2 to a mass spectrometer where the isotopic composition (e.g. 14C or 15N) is determined.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: May 28, 2013
    Assignee: Woods Hole Oceanographic Institution
    Inventors: Cameron P. McIntyre, Sean P. Sylva
  • Patent number: 8424292
    Abstract: A system for the monitoring and/or controlling emission levels of nitrogen oxide and a reductant from a stream of combustion exhaust, wherein the internal combustion engine includes a SCR unit disposed in the stream of combustion exhaust between an upstream conduit and a downstream conduit, the SCR unit having a catalyst that is configured to catalytically reduce nitrogen oxides contained in the combustion exhaust to elemental nitrogen in the presence of a reductant and oxygen, and wherein the internal combustion engine further includes a reductant injector; the system comprising: a laser absorption spectroscopy unit that is disposed in the downstream conduit and configured to measure the concentration level of at least nitrogen oxide and the reductant in the exhaust; and a control unit.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: April 23, 2013
    Assignee: General Electric Company
    Inventors: Scott M. Hoyte, Vivek V. Badami, Chayan Mitra, Ayan Banerjee
  • Patent number: 8413484
    Abstract: A method and system for rapid determination of a hydrocarbon type composition, such as crude oils and fractions thereof, and s obtaining the information necessary to assess the yield of commercially valuable fuel and lube oil fractions in a single process, variations of the method and system use Gas Chromatography-FID/Mass Spectrometry and other features, including an auto sampler, a wall coated capillary column, a temperature programmable injector, and a data processing system for compiling and processing the experimental data. The system and method further include a computer system with application software or other processing mechanism and optionally a communication network. One variation provides a graphical user interface for the entry of data and for displaying information, such as in a graphical manner, to show the relationship of various determined outputs and results.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: April 9, 2013
    Assignee: Separation Systems, Inc.
    Inventors: Joaquin A. Lubkowitz, Aaron Mendez, Roberto I. Meneghini
  • Publication number: 20130074579
    Abstract: Methods and apparatus for analyzing a sample using at least one detector are disclosed.
    Type: Application
    Filed: November 19, 2012
    Publication date: March 28, 2013
    Applicant: Alltech Associates, Inc.
    Inventor: Altech Associates, Inc,
  • Patent number: 8402814
    Abstract: A method for the analysis of isotope ratios, wherein at least one sample gas and/or at least one reference gas are supplied to at least one analytical device via at least one open split, the addition of a carrier gas also being possible. According to the invention, the concentration of the sample gas and/or reference gas passing into the analytical device is controlled by the supply of the respective carrier gas or by direct supply of the sample gas into the analytical device. In the device according to the invention for supplying gases to at least one analytical device, two or more capillaries are provided for sample gases, the capillaries in each case having their own drive for the movement between mixing zone and waiting zone.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: March 26, 2013
    Assignee: Thermo Fischer Scientific (Bremen) GmbH
    Inventors: Deike Hatscher, Andreas Hilkert, Hans-Jürgen Schlüter, Alexander Duhr, Michael Krummen, Johannes Schwieters
  • Publication number: 20130067991
    Abstract: The inventive technology may involve, in particular embodiments, novel use of a non-porous, high surface energy stationary phase to adsorb, in reversible fashion, the most polar component of a resins fraction of an input hydrocarbon when a mobile phase is passed over the stationary phase. Such reversible adsorption prevents irreversibly adsorption of such components on active stationary phase(s) downflow of the non-porous, high surface energy stationary phase, thereby conserving stationary phase costs and increasing resolution of resins elutions, and accuracy of hydrocarbon component results. Aspects of the inventive technology may also involve a novel combination of a solubility based asphaltene component fractionating and analysis method and an adsorption chromatography method for separating and/or analyzing saturate, aromatics and resins components of an input hydrocarbon.
    Type: Application
    Filed: September 20, 2011
    Publication date: March 21, 2013
    Applicant: University of Wyoming Research Corporation d/b/a Western Research Institute
    Inventors: John F. Schabron, Ryan B. Boysen, Eric W. Kalberer, Joseph F. Rovani, JR.
  • Patent number: 8367413
    Abstract: Apparatus and systems, as well as methods, may operate to draw a formation fluid sample into a sampling port included in a down hole tool or tool body, to vaporize some part of the fluid sample to substantially fill an injection port with a gas phase, to differentiate gas components in the gas phase to provide differentiated gas components along a concentration gradient in a receiving section, to detect the differentiated gas components with a detector, and to determine a fingerprint of the differentiated gas components. The receiving section may comprise a diffusion section. A reaction section and a vacuum section may be used for waste consumption and/or absorption.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: February 5, 2013
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Christopher M. Jones, Michael T. Pelletier
  • Patent number: 8365575
    Abstract: A method of performing chemical analysis is disclosed. The method includes the steps of forming carbide-derived carbon (CDC) material having a plurality of pore size, surface chemistry, and surface electrical properties. An array of the surface functionalized CDCs are used for atmospheric sampling, in which chemicals in the atmosphere are adsorbed on the CDCs. The adsorbed samples are desorbed later for analysis by a plurality of individual mass spectrometers.
    Type: Grant
    Filed: November 3, 2009
    Date of Patent: February 5, 2013
    Assignee: BAE Systems Information and Electronic Systems Integration Inc.
    Inventor: Tadd C. Kippeny
  • Patent number: 8357542
    Abstract: Provided are a suspended particulate matter measurement apparatus capable of automatically measuring a nitrate ion content and a sulfate ion content in the atmosphere, and a suspended particulate matter measurement method using the same. The suspended particulate matter measurement apparatus includes a filter, suction part, extraction part, measurement part, and a recording part. The suction part suctions air in the atmosphere at a constant flow rate to cause particulate matter contained therein to be adsorbed onto the filter. The extraction part extracts components of the particulate matter adsorbed onto the filter, by dissolving the particulate matter into a solvent, and collects a resultant solution. The measurement part measures at least one of a nitrate ion content and a sulfate ion content in the solution collected by the extraction part, and outputs the measurement result. The recording part records the measurement result outputted from the measurement part.
    Type: Grant
    Filed: April 22, 2010
    Date of Patent: January 22, 2013
    Assignee: Kimoto Electric Co., Ltd.
    Inventors: Takashi Kimoto, Yoichi Mitani, Xiang Gao, Akiko Fukunaga, Saori Kitayama