With Variable Indicator Drive Patents (Class 73/233)
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Patent number: 11300433Abstract: The present description includes a flexible sensor including a flexible substrate, a thermoelectric substrate formed on the flexible substrate, a first metal electrode that is formed on the flexible substrate and is connected to one end of the thermoelectric body, and a second metal electrode that is formed on the flexible substrate and is connected to another end of the thermoelectric body but spaced apart from the first metal electrode. The flexible sensor simply measures the temperature and the flow velocity with high accuracy. The change in temperature and flow velocity may be measured in real time. In addition, the flexible sensor may measure the temperature and the flow velocity of a fluid even when attached to a curved surface, and self-development is possible by the measurement.Type: GrantFiled: September 26, 2018Date of Patent: April 12, 2022Assignee: Korea University Research and Business FoundationInventors: Wonjoon Choi, Byungseok Seo
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Patent number: 9897474Abstract: The apparatus for monitoring the delivery of fuel oil through a fuel oil delivery pipe including a flow meter and temperature sensor associated with the oil delivery pipe for measuring the temperature and flow rate of the fuel oil as it moves through the pipe. The digital output signals from the flow meter/temperature sensor are used to generate data signals which are a function of the measured temperature and flow rate parameters. A memory records the data signals. The actual total quantity of fuel oil delivered through the pipe is calculated based upon the data signals. A clock circuit generates a timing signal reflecting the date and time the measurements were taken. A transmission signal formed of the calculated actual total quantity of fuel oil delivered and time signal may be sent to a remote location by a WiFi transmitter or through the internet using a modem.Type: GrantFiled: March 23, 2015Date of Patent: February 20, 2018Inventors: Greg Haber, Craig Kirsch
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Publication number: 20040134273Abstract: A detector (D) for detecting the volatile signature of one or more substances, e. g. alcohol and/or cannabis, on the breath (MG) of a consumer (P), using several sensors (CT1, CT2, CT3). The sensors can comprise semi-conductors or conductive polymers. The inventive detector is equipped with a filter (F) to remove nuisance substances, e. g. water vapour, which mask the signature. The detector is advantageously portable and can be used to perform a test to evaluate (E) the consumption of a substance by the driver of a motor vehicle in relation to a reference level (N). A network of formal neurones (RN) is used to generate a database (DB) that is used to calibrate the detector.Type: ApplicationFiled: March 9, 2004Publication date: July 15, 2004Inventors: Jean- Luc Clement, Francoise Farnarier, Florence Marquis, Bernard Boeuf
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Patent number: 6378366Abstract: The cam drive exhibits a part rotable about an axis. The part is unrotatably connected to a cam element. A swivel arm for a sensing element is pivot-mounted on the cam element. A temperature-dependent compensation element is provided which is supported on the cam element and engages in the swivel arm to determine the position thereof. The sensing element is arranged on the swivel arm such that it can be moved and engages in a recess of the cam element. The recess is adapted to the type-specific temperature dependence of the temperature-sensitive device which the cam drive forms a part of. The error curve of the temperature-dependence device can be optimized by appropriate radial and tangential adjustment of the sensing element (stroke and advance), caused by the compensation element and determined by the corresponding design of the recess.Type: GrantFiled: March 2, 2000Date of Patent: April 30, 2002Assignee: G. Kromschröder AktiengesellschaftInventor: Klaus Penning
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Patent number: 6150177Abstract: A device comprising a combination of a mouthpiece (2) with a holder (1), which receives the mouthpiece (2) and has a sampling channel (4) leading to a breath alcohol-measuring device and a temperature sensor (11) arranged in the connection area between the holder (1) and the mouthpiece (2). To make it possible to determine the temperature of the mouthpiece (2) inserted into the holder (1) the mouthpiece (2) is designed for the temperature sensor (11) to be arranged in the sampling channel (4) as a wall section (10) covering the inner wall of the sampling channel (4) in the area of the temperature sensor (11).Type: GrantFiled: August 11, 1998Date of Patent: November 21, 2000Assignee: Drager Sicherheitstechnik GmbHInventor: Burkhard Stock
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Patent number: 6148658Abstract: A system and method are set forth for photoacoustical analysis of isotope and other compounds having telltale absorption wavelengths between 1700-2500 nm. The system and method includes a Co:Mg F.sub.2, optical parametric oscillator (OPO) or diode laser tunable between 1700-2500 nm which is directed into a sample at energies sufficient to generate detectable acoustical emissions. A microphone detects the emissions for processing and analysis. The system and method is adapted to detect stable isotope compounds such as .sup.13 CO.sub.2 as well as other chemical compounds. For non-gaseous compounds, a CO.sub.2 or diode laser is used to photoablate the baseous sample containing the suspected compounds.Type: GrantFiled: March 16, 1998Date of Patent: November 21, 2000Assignee: TRW Inc.Inventor: Mau-Song Chou
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Patent number: 6129680Abstract: Apparatus and a method for monitoring animal exhalation, to provide an indication of the condition of an animal is disclosed. Apparatus for collection and temporary or permanent storage of animal exhalation sample is disclosed, together with apparatus for conditioning a sample prior to analysis. A method of conditioning a sample prior to analysis is also disclosed.Use may be made of the above mentioned apparatus and method in the diagnosis of the condition of an animal. Conditions of interest include metabolic conditions of animals such as dairy cattle; these can be monitored by measuring analytes in the exhaled breath, emanations from the milk or both. Use may also be made of said apparatus and method in the detection of antibodies present in samples of blood, milk and mucus particulates in exhaled breath. It is preferred that the monitoring apparatus is portable.Type: GrantFiled: December 18, 1997Date of Patent: October 10, 2000Assignee: BTG International LimitedInventor: Toby Trevor Fury Mottram
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Patent number: 6130614Abstract: A vehicle trunk detection and release system 10 which detects the presence of an individual within a trunk 14 and which releases the trunk 14, energizes the horn 16, and/or activates the headlights 17 upon such a detection. The system 10 further includes an illuminated touch pad 28 which opens the trunk 14 upon being touched.Type: GrantFiled: November 10, 1999Date of Patent: October 10, 2000Inventors: Ronald H. Miller, Gary S. Strumolo
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Patent number: 6099480Abstract: The present invention relates to apparatus for determining a relevant proportion (a) of a chosen gas, an NO-gas or NO.sub.2 -gas, present in a gas mixture (A), such as in a gas mixture deriving from the expiration air or inspiration air of a living being (1), wherein an adapted sample proportion of the breathing air is passed from an outlet (11) in the immediate vicinity of said being, via a hose (10') or the like, to measuring equipment (13') that includes a measuring chamber (14') that is placed under a subpressure and to which ozone gas is also supplied, wherewith the nitrogen oxide present reacts with the ozone-gas to form NO.sub.2 and light, and wherein the apparatus includes a light measuring unit (13') which is adapted to evaluate the light thus generated and to calculate (18) the amount of predominant gas in the breathing air on the basis of this evaluation. The volume (14b') of the measuring chamber of such apparatus is adapted to include the volume enclosed in the hose (10') used.Type: GrantFiled: May 14, 1999Date of Patent: August 8, 2000Assignee: Aerocrine ABInventor: Lars Erik Gustafsson
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Patent number: 6096558Abstract: A process for calibrating a breath alcohol-measuring instrument (7) with a calibrating gas generator (1) with a liquid container (2) for aqueous ethanol solution and air feed device, which allow air to bubble through the ethanol solution and for passing gas from the atmosphere above the ethanol solution to the breath alcohol-measuring instrument (7).Type: GrantFiled: February 11, 1998Date of Patent: August 1, 2000Assignee: Drager Sicherheitstechnik GmbHInventor: Burkhard Stock
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Patent number: 6076392Abstract: A method and apparatus for real time gas analysis involving determining individual concentrations of fluid constituents in a mixture of known constituents by measuring properties of the mixture and solving a set of equations, which relate the individual gas concentrations to the measured properties of the mixture, for the unknown individual gas concentrations. The individual concentrations of four gasses in a mixture are determined by: passing the mixture through a flowmeter, a capillary, an orifice, and a sonic oscillator; transducing temperature, pressure and acoustic frequency measurements taken from the sensors; determining the density, viscosity, and the specific heat of the mixture; forming three equations which respectively relate these three properties to individual gas concentrations; and solving the three equations and the constitutive equation which requires that the sum of the concentrations equal unity, for the four unknown individual gas concentrations.Type: GrantFiled: June 26, 1998Date of Patent: June 20, 2000Assignee: metaSENSORS, Inc.Inventor: Tadeusz M. Drzewiecki
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Patent number: 6067989Abstract: A breath test for diagnosing the presence of Helicobacter pylori in a subject is described. The method of diagnosing Helicobacter pylori is performed as follows. First, a safe and effective amount of urea, preferably appropriately labelled, is administered to the subject. Second, a plurality of the exhaled breaths of the subject is analyzed to detect the concentration of a cleavage product or products, produced when urease cleaves the substrate. The measured concentrations are then fitted to a curve, and the derivative is then calculated, to indicate the presence or absence of Helicobacter pylori infection in the subject.Type: GrantFiled: February 26, 1997Date of Patent: May 30, 2000Assignee: Oridion Medical, Ltd.Inventor: Daniel E. Katzman
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Patent number: 6050953Abstract: A device and method for measuring critical portions of an individual's forced expiratory efforts. The device includes a series of preset negative pressure sensors attached to a sensor port located in a breathing tube of predetermined dimension. A patient blows through the breathing tube triggering the various sensors depending on the airflow rate. The time each of the sensors are activated is recorded. The recorded information can be used to determine various diagnostic parameters.Type: GrantFiled: May 21, 1998Date of Patent: April 18, 2000Inventors: Warren J. Warwick, Leland G. Hansen
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Patent number: 6038913Abstract: A device for determining the level of nitric oxide in an exhaled airstream belonging to a living organism selected to have its lung function evaluated, where an initial device is arranged to determine the current portion of nitric oxide and/or the distribution of nitric oxide over time during an exhalation phase. During the commencing period of the exhalation phase, the exhaled air is arranged to pass with no or with only a very small resistance or back-pressure to a free space, and during the remaining period, the exhaled air is arranged to pass through the initial device against the action of a suitable resistance or back-pressure. The level of nitric oxide is measured during this remaining period.Type: GrantFiled: March 20, 1998Date of Patent: March 21, 2000Assignee: Aerocrine ABInventors: Lars Erik Gustafsson, Gunnar Magnus Severus Persson, Stefan Per Axel Stromberg
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Patent number: 6033367Abstract: A system for diagnosing or monitoring sucking/swallowing/breathing competence of an impaired neonate or post-operative infant, wherein a processor receives a sensed signal from a breath sensor, and develops an output for intraoral tactile or flow control feedback. In a feeding or monitoring embodiment, the processor applies the signal to control a liquid feeding valve which supplies nutrients through a feeding nipple. In various control regimens, the processor acts as a safety device and operates to restrict or close the valve to reduce flow when slowing or cessation of breath is detected, or acts as a training device to set or pace, or initially to develop basic competence, at an appropriate rate. In further embodiments, the processor also receives a signal from an intraoral suction transducer or muscle pressure gauge, and operates to control flow to a level appropriate to the available sucking activity, or to change the level to maintain a stable and non-slowing breath rate.Type: GrantFiled: August 10, 1998Date of Patent: March 7, 2000Assignee: Children's Medical Center CorporationInventor: Eugene C. Goldfield
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Patent number: 6033368Abstract: Disclosed is a device for determination of the content of higher oxides of nitrogen in exhaled breath condensate which comprises a conduit having an exhalate condensing portion with an inlet and an outlet (the inlet canbe configured to fit with a mechanical respirator or, for direct use by the patient, an inlet assembly providing one-way ingress of ambient atmosphere to the device can be associated with the inlet of the conduit exhalate condensing portion); a coolant jacket coaxially surrounding said exhalate condensing portion; a gas release port; and, in enclosed fluid communication with said conduit exhalate condensing portion outlet, a sample assay assembly comprising (i) a translucent analysis chamber attached to the outlet to receive condensate fluid and having a reagent entry port, (ii) a reagent chamber in enclosed fluid communication with the reagent entry port and (iii) a pliable element connecting the outlet and the analysis chamber and forming a portion of the reagent chamber such that flexion ofType: GrantFiled: March 28, 1996Date of Patent: March 7, 2000Assignee: NitroMed, Inc.Inventors: Benjamin M. Gaston, IV, John F. Hunt
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Patent number: 6026674Abstract: An apparatus and method for determining the concentration of alcohol present in a gaseous mixture wherein an electronic device employing a fuel cell determines the concentration of alcohol present in the gaseous mixture is disclosed. In particular, the device may be used to determine a person's sobriety by determining the alcohol concentration in a breath sample. To determine the alcohol concentration, the device must be able to accurately determine the volume of breath in the breath sample. The device controls the volume of the breath sample by measuring the pressure of the breath flow through the device and, in response to the pressure, electronically controlling a valve diverting a portion of the breath flow into the fuel cell thereby indicating and ensuring that a predefined requisite amount of breath flow has passed thru the fuel cell.Type: GrantFiled: August 20, 1998Date of Patent: February 22, 2000Assignee: Smart Start Inc.Inventor: Robert Scott Gammenthaler
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Patent number: 6001064Abstract: A measuring device for determining the concentration of such gas components from a gas mixture, which includes collision dilation of the absorption lines constituting the absorption spectral bands for measuring objects. The device comprises a non-dispersive concentration measuring sensor (20), which includes: a measuring chamber (6) containing a gas mixture to be analyzed; a radiation source (17) for emitting over a wavelength range which includes an absorption spectral band used in concentration determination; a detector (18) receiving radiation that has passed through the measuring chamber and for producing a first signal (7) therefrom; as well as an optical bandpass filter (16) positioned between the detector and the radiation source. The measuring device further comprises a second measuring sensor (4) for identifying the viscosity or some other viscosity-related feature of a gas mixture to be analyzed and for producing a second signal (9).Type: GrantFiled: September 15, 1997Date of Patent: December 14, 1999Assignee: Instrumentarium OyInventor: Kurt Peter Weckstrom
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Patent number: 5971937Abstract: A method and apparatus for measuring a blood alcohol content value by means of a breath alcohol concentration as well as for securing the reliability of this measured value. The apparatus comprises: sensor elements (1) for obtaining a measured alcohol concentration value from an incoming exhalation air stream; sensor elements (1) for obtaining a measured carbon dioxide concentration value from the same exhalation air stream (9); as well as first output elements (2) for producing, if necessary, a result proportional at least to a blood alcohol content.Type: GrantFiled: June 25, 1996Date of Patent: October 26, 1999Assignee: Instrumentarium OyInventor: Jan Petri Ekstrom
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Patent number: 5964712Abstract: A correction curve (FIG. 19) is prepared by plotting .sup.12 CO.sub.2 concentrations and .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratios which are determined on the basis of a calibration curve and .sup.13 CO.sub.2 and .sup.12 CO.sub.2 absorbances of gaseous samples having the same .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio but known different .sup.12 CO.sub.2 concentrations. A gaseous test sample containing .sup.13 CO.sub.2 and .sup.12 CO.sub.2 as component gases is introduced into a cell, and spectrometrically measured. A .sup.12 CO.sub.2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the .sup.12 CO.sub.2 concentration of the gaseous test sample thus determined. A measured .sup.13 CO.sub.2 /.sup.12 CO.sub.2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the .sup.13 CO.sub.2 /.sup.12 CO.sub.Type: GrantFiled: June 6, 1997Date of Patent: October 12, 1999Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Yasuhiro Kubo, Katsuhiro Morisawa, Yasushi Zasu, Eiji Ikegami, Kazunori Tsutsui, Tamotsu Hamao, Masaaki Mori, Takashi Maruyama
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Patent number: 5962335Abstract: A breath test for determining the rate of metabolism of a drug is described. First, a safe and effective amount of the drug, preferably appropriately labelled and most preferably isotopically-labelled, is administered to a subject. After a suitable time period, the exhaled breath of the subject is analyzed to determine the concentration of a metabolite. The concentration of the metabolite is then used to determine the rate of metabolism of the drug. A breath test kit is also described. Such a breath test kit would include an item or items necessary for performing at least one of the methods of determining the rate of metabolism of a drug in a subject. For example, such a breath test kit could include an isotopically-labelled drug to be administered to the subject.Type: GrantFiled: January 3, 1997Date of Patent: October 5, 1999Assignee: Oridion Medical Ltd.Inventor: Daniel E. Katzman
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Patent number: 5948962Abstract: A codable gas detection system with at least one interchangeable gas sensor (2), which has standardized plug-type connections (5,6) between the gas sensor (2) and the measuring device (1), but is also able to prevent measured values of an unauthorized gas sensor (2) from being processed. Each gas sensor (2) contains a memory (3) with gas sensor-specific data and is connected via a line to the measuring device (1) with a first calculating and evaluating unit (7), to a downstream memory (8) and preferably to an alarm device (10). Via the second plug-type connection (5), the sensor element (4) proper is connected to a contacting unit (9) in the measuring device (1), and the contacting unit (9) is connected to the first calculating and evaluating unit (7), on the one hand, and to a downstream, second calculating and evaluating unit (11) for the measured value evaluation proper, on the other hand.Type: GrantFiled: January 20, 1998Date of Patent: September 7, 1999Assignee: Dragerwerk AGInventor: Hans Matthiessen
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Patent number: 5932877Abstract: An side stream infrared gas analyzer for detecting the concentration of a gaseous component of a substantially gaseous flow stream such as the expired air of a patient under anesthesia. The infrared gas analyzer comprises an infrared energy detector, a sample cell, and an infrared energy source which are designed to be small and to consume relatively little electrical power. The infrared energy detector converts the received incident radiation into at least one electrical signal representative of the received incident radiation and is preferably mounted directly onto a printed circuit board containing signal processing circuitry which processes the electrical detection signals provided by the infrared energy detector. The infrared energy detector also has a first infrared transmissive window on a detection side thereof through which the incident radiation passes for detection.Type: GrantFiled: April 17, 1997Date of Patent: August 3, 1999Assignee: Square One Technology, Inc.Inventors: James R. Braig, Daniel S. Goldberger
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Patent number: 5929319Abstract: This invention consists of breath testing apparatus 10 comprising a breath tube 11, a fuel cell housing 12 incorporating a pump system 12a, a fuel cell 13, a control and computational unit 14, and a display 15. A thermistor 22 is provided to detect the temperature of the housing 12 during measurement and the unit 14 compensates the fuel cell output in accordance with the detected temperature.Type: GrantFiled: December 17, 1997Date of Patent: July 27, 1999Assignee: Lion Laboratories PlcInventors: Paul King, Jason Aspinall
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Patent number: 5849594Abstract: A carbon dioxide sensitive material including a polymer binder, a plasticiser, a lipophilic organic quaternary cation, an indicator dye anion and an aromatic alcohol in such concentration that the material changes color in accordance with the concentration of carbon dioxide.Type: GrantFiled: May 16, 1997Date of Patent: December 15, 1998Assignee: Sealed Air (NZ) LimitedInventors: Simon Neville Balderson, Robert John Whitwood, Andrew Mills, Lela Margaret Monaf
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Patent number: 5834626Abstract: Colorimetric indicators for breath, air, gas, & vapor analyses that can be thrown away after a single use, are easy to use, low cost, small, and simple to manufacture for indicating at least volume passed through the colorimetric indicators and may also be used to indicate concentration of an analyte within breath, air, gas, & vapor passed through the colorimetric indicators. The present invention is directed to colorimetric indicators for breath, air, gas, & vapor analyses. The colorimetric indicators may have a housing with an entrance port, an outlet, a volume indicator, and an analyte indicating reagent. The volume indicator may be a breath volume reagent. Different analytes may be measured, the analyte indicating reagent depending upon the particular analyte being to monitored. The breath volume indicator is colorimetric, and changes color when a predetermined volume of air is passed through the colorimetric indicators for breath, air, gas, & vapor analyses.Type: GrantFiled: November 29, 1996Date of Patent: November 10, 1998Inventors: Emory S. De Castro, Douglas R. Malat
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Patent number: 5802909Abstract: An apparatus and an associated method for monitoring compliance with a disulfiram prescription regime. A self testing device 10 includes a gas sensor 12, a display 13, an indicating light 14, and a start button 15. An air inlet 16 is joined on the body 11 and a breath tube 12 can be located therein. A clock 20 in association with a random day generator 21 and the display 13, and light 14 determine the daily close rate and the measured sample is compared with expected sensor output by determining whether or not the user has complied with the regime.Type: GrantFiled: February 26, 1997Date of Patent: September 8, 1998Inventors: George Charles Faulder, Richard Martin Faulder, Roger Neil Bloor
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Patent number: 5770793Abstract: The invention is directed to a measuring method for determining the concentration of a gas in a measurement sample with the aid of a combined measuring apparatus. The measuring apparatus includes a first infrared optical gas analyzer 1 as well as a second gas analyzer 2, which contains an electrochemical measuring cell 13. The measuring result of the electrochemical measuring cell 13 functions to correct the concentration, which is determined by the infrared optical gas analyzer 1, when the infrared optical reference measurement has already been performed on a measurement sample with this measuring sample not being free of the substance to be detected.Type: GrantFiled: February 20, 1997Date of Patent: June 23, 1998Assignee: Dragerwerk AktiengesellschaftInventor: Burkhard Stock
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Patent number: 5739412Abstract: The combination of the invention includes a mouthpiece 1 and a sample-taking system 8 for analyzing a gas sample. The mouthpiece 1 has a flow resistor 5 in the exhalation direction and a sample-taking connecting element 6 for the gas sample to be analyzed. The sample-taking system 8 has a pump and a through-flow measuring device 13. The pump pumps the sample gas flow from the sample-taking connecting element via a sample line 9 into a measuring chamber 15 of an analyzer 16. The combination is improved in such a manner that calibration is made possible with a calibrating gas flow greatly reduced compared to the flow of gas to be measured. This is achieved in that the sample-taking connecting element 6 is connected to the mouthpiece 1 forward of the flow resistor 5 viewed in the exhalation direction. The sample line 9 includes a flow throttle 11 in through-flow direction and an outlet opening 12 opening to the ambient.Type: GrantFiled: December 4, 1996Date of Patent: April 14, 1998Assignee: Dragerwerk AktiengesellschaftInventors: Burkhard Stock, Jurgen Sohege
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Patent number: 5734090Abstract: A method and apparatus for verifying an expiratory breath flow utilizes the sonic characteristics of a standardized breath as a reference. A breath sample is analyzed for the presence and absence of predetermined audio frequency components generated by the expiratory process. Breach sample validity is based upon a match between both the required and missing components. The length of time that the required components are present can further be used to validate the sample.Type: GrantFiled: March 27, 1996Date of Patent: March 31, 1998Assignee: Alcohol Sensors International, Ltd.Inventors: Ronald Koppel, Edwin Kirchmeier
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Patent number: 5705735Abstract: A system for real time, breath by breath sampling of a patient receiving up to 100 percent oxygen to determine nutritional requirements of the patient through indirect calorimetry includes a pneumotach member for measuring the volume rate of flow of inspired and expired gas flow at the patient/endotracheal tube/ventilator connection. A sample line extends from the pneumotach to a gas analyzer which measures the percent concentration of constituent respiratory gases in the expired gas flow. A flowmeter is coupled to the gas analyzer for determining the volume flow rate of the expiratory gas flow through the sample line. A microprocessor control samples the analog electrical signals from the gas analyzer, the flow meter and the pneumotach in a predetermined sequence, dynamically compensating for variations in gas flow rate.Type: GrantFiled: August 9, 1996Date of Patent: January 6, 1998Assignee: Medical Graphics CorporationInventor: Russell G. Acorn
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Patent number: 5679884Abstract: A resuscitator is provided with an integral carbon dioxide detector for indicating the presence of carbon dioxide in a patient. The carbon dioxide detector is a conventional pH sensitive chromogenic compound that is positioned in the breathing circuit to permit a rapid indication. Additionally, a unique plug is provided for sealing the indicator from the atmosphere while in storage to prevent contamination and degredation of the indicator compound.Type: GrantFiled: August 11, 1995Date of Patent: October 21, 1997Inventor: Gilbert M. Kirk
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Patent number: 5679535Abstract: An apparatus for collecting antigen, including an allergen exemplified by a dust-mite, dispersed in a motile fluid in a given environment that can be inserted in a section of a pipe of a standard vacuum cleaner hose. The apparatus includes a receptacle whose body is formed of nylon, typically with a pore size of from 15 to 60 .mu.m. The receptacle is coated with an antibody that retains the antigen in a contacting relationship. The apparatus is provided with a removable holder, which assists in locating the apparatus in the pipe of the vacuum cleaner. The apparatus can be used directly in an immunoassay for confirming the presence of, or quantifying, the antigen.Type: GrantFiled: December 5, 1994Date of Patent: October 21, 1997Assignee: University Collge DublinInventors: Patrick Joseph Joyce, Edmund Bruce Mitchell, Alan Gaylard Shattock
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Patent number: 5611348Abstract: The invention relates to a portable collection container (5) for a test person, and a method for measuring and analyzing the expiration gas collected into the container (5). The container (5) is made of laminate. In the method, the container when discharged by low pressure suction, is folded into its original folded state.Type: GrantFiled: September 23, 1994Date of Patent: March 18, 1997Assignee: Instrumentarium Corp.Inventor: Pekka Merilainen
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Patent number: 5573005Abstract: A syringe for collecting expiration is switched, to be connected by a three-way electromagnetic valve, between an expiration blowing part and a measuring part, so that expiration, blown from the expiration blowing part, is collected in the syringe while replacing old expiration. A switching valve is closed upon completion of exhalation so that end-tidal air is collected in the syringe. Thereafter the expiration sample is introduced into the measuring part from the syringe so that a constant amount of the expiration sample is collected by the measuring part to be introduced into a column.Type: GrantFiled: October 24, 1994Date of Patent: November 12, 1996Assignee: Kyoto Dai-ichi Kagaku Co. Ltd.Inventors: Hideo Ueda, Mitsuo Hiromoto, Meng Gang, Yutaka Yamasaki
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Patent number: 5533513Abstract: An expiration suction passage communicating with an expiration blowing part provided with a non-airtight mask is connected to a forward end surface of a syringe through a two-way on-off electromagnetic valve, while an expiration transmission passage communicating with a sample outlet is also connected to the forward end surface of the syringe. A two-way on-off electromagnetic valve is provided in the expiration transmission passage, and an O.sub.2 sensor is provided between the electromagnetic valve and the sample outlet as a standard gas sensor. The syringe has a capacity capable of collecting several breaths, and a sucking operation is driven at a speed for collecting several breaths in single suction.Type: GrantFiled: October 24, 1994Date of Patent: July 9, 1996Assignee: Kyoto Dai-Ichi Kagaku Co., Ltd.Inventors: Hideo Ueda, Mitsuo Hiromoto, Meng Gang, Yutaka Yamasaki
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Patent number: 5531225Abstract: There is provided a measuring apparatus for alcohol contained in an exhalation, the measuring apparatus measuring concentration of alcohol with a high accuracy in a short time. An alcohol sensor is provided inside an air passage to measure concentration of alcohol contained in air passing through the air passage. The alcohol sensor has a sensing element for sensing alcohol and a heating element for heating the sensing element. A suction pump is provided to the air passage so as to suction air from an inlet of the air passage. The sensing element is situated inside an air trapping chamber so that the air flowing through the air passage does not directly hit the sensing element.Type: GrantFiled: October 13, 1994Date of Patent: July 2, 1996Assignees: Toyota Jidosha Kabushiki Kaisha, Kabushiki Kaisha Toyota Chuo KenkyushoInventors: Katsumi Nawata, Fumihiro Ushijima, Toshiyuki Taguchi, Hazime Inagaki
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Patent number: 5531096Abstract: A method for gas analysis includes the steps of extracting a gas sample from a gas to be analyzed with respect to one or more of its gas components, measuring the flow of the extracted gas sample, and adding a replacement gas to the gas in the same amount as the extracted sample in order to minimize the impact on the main gas flow of the extraction of the gas sample. The replacement gas can consist of the same gas components constituting the gas sample. A gas analyzer for performing the method is also disclosed.Type: GrantFiled: November 17, 1994Date of Patent: July 2, 1996Assignee: Siemens Elema ABInventor: Rolf Castor
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Patent number: 5517985Abstract: An apparatus (14) for detecting carbon dioxide in exhaled gas is disclosed. The apparatus comprises an indicating element (10) for changing color when exposed to carbon dioxide and a carbon dioxide shield (12) for absorbing a predetermined level of carbon dioxide from the exhaled gas before exposing the indicating element (10) to the exhaled gas.Type: GrantFiled: November 2, 1994Date of Patent: May 21, 1996Inventors: Gilbert M. Kirk, James D. Bickley
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Patent number: 5501231Abstract: A method and system for testing and recording the peak expiratory flow rate (PEFR), forced expiratory volume (FEV. 1) and forced volume capacity (FVC) of a patient, comprises prompting the patient to cause the sensing of the expiratory flow rate, sensing the expiratory flow rate of the patient and generating a signal representative of this biological condition, processing the signal to generate biological data representative of the biological condition, generating time data representative of the time when the biological condition was sensed, storing the biological data and the time data, and retrieving the stored biological data together with the time data.Type: GrantFiled: June 2, 1993Date of Patent: March 26, 1996Inventor: Norman Kaish
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Patent number: 5497651Abstract: A method and a system for analyzing gas samples employ at least two semiconductor sensor sets, used alternately. The sensor output signals are time-differentiated. As a result of these features, the time required for analysis can be reduced considerably, especially with an uninterrupted sequence of analyses to be performed in succession.Type: GrantFiled: September 13, 1994Date of Patent: March 12, 1996Assignee: Martin LehmannInventors: Ulrich Matter, Rene Nunlist, Heinz Burtscher, Michael Mukrowsky
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Patent number: 5495744Abstract: A first sample measuring passage provided between a collection port and a suction pump has a sample gas measurer for measuring expiration components, while a second sample measuring passage which is provided in parallel with the first sample measuring passage has a standard gas measurer for measuring O.sub.2 gas. Assuming that [A] represents a measured value of a target component in an expiration sample and [b.sub.1 ] represents O.sub.2 concentration in the expiration sample, correction is made on the basis of:[M]=f.sub.1 .multidot.(21-[a.sub.1 ]) [A]/(21-[b.sub.1 ])where [M] represents the corrected measured value of the target component, [a.sub.1 ] represents O.sub.2 concentration in end-tidal air which is supplied as a constant such as 15.3, for example, and f.sub.1 represents an experimentally prescribed coefficient such as 1.67, for example.Type: GrantFiled: October 24, 1994Date of Patent: March 5, 1996Assignee: Kyoto Dai-Ichi Kagaku Co., Ltd.Inventors: Hideo Ueda, Mitsuo Hiromoto, Meng Gang, Yutaka Yamasaki
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Patent number: 5479815Abstract: The invention provides a method and apparatus for efficiently measuring and analyzing volatile and relatively non-volatile flavor components released during oral processing of food or other products. The subject exhales a breath sample into one or more temperature-controlled collection chambers, preferably at predetermined time intervals during the oral processing of the product. Each breath sample is then purged from its collection chamber with a non-reactive gas flow into an adsorbent, absorbent or other trap containing an interface that separates and collects the volatile and relatively non-volatile components from the breath sample. The trap is then transferred to a thermal desorber to release the volatile and relatively non-volatile flavor components from the interface surface into a measuring and analysis apparatus.Type: GrantFiled: February 24, 1994Date of Patent: January 2, 1996Assignee: Kraft Foods, Inc.Inventors: James D. White, William R. Croasmun, Jane V. Leland
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Patent number: 5458853Abstract: A dual breath analysis device having a passive first mode of testing and analysing an exhaled breath sample without the use of a mouthpiece, and a second mode of testing and analysing a second breath sample through a mouthpiece apparatus when the first mode of testing indicates a substantially high level of alcohol in the first breath sample.Type: GrantFiled: September 30, 1993Date of Patent: October 17, 1995Assignee: Lion Analytics Pty. Ltd.Inventors: Anthony Porter, Robert Breakspere
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Patent number: 5454375Abstract: A pneumotachograph mask or mouthpiece coupling element may reduce the distortion and muffling of the voice otherwise caused by a mask or mouthpiece when measuring the low-frequency components of a volume-velocity of oral or nasal airflow during speech or singing. This improved performance is accomplished by separating the low-frequency components to be measured from the higher frequency or acoustic components by an acoustic filter. The filter passes much of the acoustic energy through the walls of the mask or mouthpiece at a location or locations close to the face. The lower frequency airflow components are funneled by the mask or mouthpiece coupling element through an airflow-measurement transducer. The acoustic filtering can be implemented by a membrane, or array of membranes, in the wall of a chamber located close to, or formed as part of, the mask or mouthpiece.Type: GrantFiled: October 21, 1993Date of Patent: October 3, 1995Assignee: Glottal EnterprisesInventor: Martin Rothenberg
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Patent number: 5443794Abstract: This invention relates to apparatus for measuring the concentration of a volatile component in a gas and in particular, but not exclusively, to breath alcohol testing apparatus.In such apparatus 10, a pressure transducer 15 is provided to detect the ambient pressure during test. This pressure is used to modify the output of a fuel cell 11.Type: GrantFiled: May 6, 1991Date of Patent: August 22, 1995Assignee: Lion Technology LimitedInventor: Paul M. Williams
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Patent number: 5425374Abstract: A portable type clinical examination device using expiratory air of a patient as a sample and measuring with high accuracy and rapidity concentration of trace amounts of aimed gas components contained in the expiratory air. The clinical examination device feeds an expiratory air sample provided by a patient, fed through an expiratory air sucking portion and separated in a column to a detector which detects trace amounts of aimed gas components contained in the expiratory air sample by ionizing the aimed gas components through application of ultraviolet or radiation, so that output signals from the detector are processed and concentration of the aimed gas components is computed by use of a previously memorized working curve to provide a clinical examination data which is output on a recording device or the like.Type: GrantFiled: June 3, 1993Date of Patent: June 20, 1995Assignees: Hideo UEDA, Kabushiki Kaisha Kyoto Daiichi KagakuInventors: Hideo Ueda, Mitsuo Hiromoto
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Patent number: 5404885Abstract: A noninvasive device and methods for measuring the end-tidal carbon monoxide concentration in a patient's breath, particularly newborn and premature infants. The patient's breath is monitored. An average carbon monoxide concentration is determined based on an average of discrete samples in a given time period. The ratio of the end-tidal portion of the breath flow sample is separately determined, preferably based on monitoring the level of carbon dioxide in the gas sample and identifying the carbon dioxide concentration levels corresponding to the end-tidal portion of the breath sample. The sensed carbon monoxide level is converted to the end-tidal carbon monoxide level by subtracting the ambient carbon monoxide level and dividing the remainder by the ratio of end-tidal breath to breath in the breath sample.Type: GrantFiled: January 21, 1994Date of Patent: April 11, 1995Assignee: Natus Medical, IncorporatedInventors: Neil J. Sheehan, Scott R. Rouw, Robert T. Stone
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Patent number: 5402796Abstract: The arterial CO.sub.2 monitor and closed loop controller for use with a ventilator monitors a patient's breath and determines PaCO.sub.2 based upon a determination of a deadspace ratio, which is the ratio of the alveolar deadspace to alveolar tidal volume. The method generally comprises the steps of continuously monitoring measurable parameters of a patient's breath; obtaining an input value of PaCO.sub.2 from a blood sample of the patient and using the patients breath parameters and the input value to calculate the deadspace ratio; and continuously determining PaCO.sub.2 based on the assumption that the deadspace ratio subsequently remains constant. Decision rules obtained from other measurable data are preferably also used to identify the onset of changes in the deadspace ratio, and a new deadspace ratio is then determined from the patient's breath parameters and further input value of PaCO.sub.2 from the patient's blood sample.Type: GrantFiled: April 21, 1993Date of Patent: April 4, 1995Assignee: University of MelbourneInventors: John S. Packer, John F. Cade, Eng-Boon L. Law
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Patent number: 5400637Abstract: A system and method for checking the calibration of a breath alcohol measuring instrument by the use of alcohol standards all containing substantially identical concentrations of alcohol and the use of a calculator which generates an expected measured value for the standard based on the known alcohol concentration and current atmospheric pressure.Type: GrantFiled: December 21, 1993Date of Patent: March 28, 1995Assignee: Intoximeters, Inc.Inventor: Glenn C. Forrester