Peptides Containing Saccharide Radicals And Having A Fully Defined Sequence Of Amino Acids And Wherein The Peptide Sequence Is Not Part Of A Ring Structure, E.g., Bleomycin, Phleomycin, Muramylpeptides, Etc., (c07k-9/00d, 9/00d2, 9/00d4, 9/00d9) Patents (Class 930/DIG500)
  • Patent number: 5696082
    Abstract: Compounds of general formula (I) wherein X is --CONHOH or --CO.sub.2 H, principally characterised by the presence in substituent R.sub.3 and/or R.sub.4 of a group of formula (II) are inhibitors of matrix metalloproteinases and inhibitors of the production of turnout necrosis factor.
    Type: Grant
    Filed: May 28, 1996
    Date of Patent: December 9, 1997
    Assignee: British Biotech Pharmaceuticals Limited
    Inventors: Michael John Crimmin, Andrew Paul Ayscough, Raymond Paul Beckett