And Aliphatic (c07k-5/10a1) Patents (Class 930/DIG785)
  • Kinetic assay for endotoxin using limulus amebocyte lysate and chromogenic substrate
    Patent number: 5310657
    Abstract: A kinetic assay procedure is provided which permits measurement of endotoxin concentration in the range from 0.005 EU/ml to 50 EU/ml. The assay procedure relies on a single reagent substrate composition comprising Limulus amebocyte lysate and a chromogenic substrate. This assay procedure is easily automated and it provides substantial improvement in both range and sensitivity over previously available endotoxin assays.
    Type: Grant
    Filed: July 13, 1992
    Date of Patent: May 10, 1994
    Assignee: Whittaker Bioproducts, Inc.
    Inventor: Ronald N. Berzofsky