Linear Peptides Containing At Least One Abnormal Peptide Link And Derived From 5-100 Amino Acids (c07k-7/02) Patents (Class 930/DIG790)
  • Patent number: 5162497
    Abstract: A bradykinin analog which contains nine or ten amino acid residues and at least one [CH.sub.2 NH] pseudopeptide bond, the analog being useful as an antagonist or agonist of the naturally occuring bradykinin.
    Type: Grant
    Filed: December 9, 1988
    Date of Patent: November 10, 1992
    Assignee: The Administrators of the Tulane Educational Fund
    Inventors: David H. Coy, Jacques-Pierre Moreau, John E. Taylor, Sun H. Kim
  • Patent number: 5140103
    Abstract: A method of determining collagen degradation in vivo, including quantitating the concentration of a peptide in a body fluid, the peptide being a C-terminal type II collagen telopeptide containing a hydroxylysyl pyridinoline cross-link or a type III collagen telopeptide containing a hydroxylysyl pyridinoline cross-link. The method includes immunometric assays, fluorometric assays, and electrochemical titrations for quantitation. The structures of specific peptides having cross-links and kits for quantitating these peptides in a body fluid are described.
    Type: Grant
    Filed: December 1, 1989
    Date of Patent: August 18, 1992
    Assignee: Washington Research Foundation
    Inventor: David R. Eyre