Abstract: A multi-purpose stationery box set including a semi-spherical lower casing, an upper cover pivotally coupled to the semi-circular lower casing, an inner holder set disposed in the lower casing, a bottom block having a drawer and being connected to the lower casing at the bottom thereof. The inner holder is integrally formed therein by an injection molding process to provide a variety of spacings having different sizes and shapes for the convenient arrangement of various stationery accessories in an efficient way with minimized space consumption. By means of the professional design of the stationery box, an attractive outer appearance is provided. Thus, in addition to its multi-purpose usage, it is also very practical and can serve as a decorative ornament.